KOGA Hironori 古賀浩徳

Researcher Number	90268855
Other IDs
External Links
Affiliation (Current)	2025: 久留米大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 久留米大学, 医学部, 教授 2014: 久留米大学, 医学部, 准教授 2011 – 2013: 久留米大学, 医学部, 講師 2004 – 2006: Kurume University, Assistant Professor, 医学部, 講師 1997 – 2003: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology / Basic Section 48030:Pharmacology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Metabolomics / Tumor therapeutics
Keywords	Principal Investigator p27 / TCF-4 / Wnt / Wntシグナル / T-cell factor-4 / G1 arrest / Bcl-xL / MRP2 / Skp2 / p21 … More / PPARγ / apoptosis / VEGF / COX-2 / Hes1 / isoform / 免疫回避機構 / 非古典的Wntシグナル経路 / Wnt5a / Splicing variant / TCF7L2 / variant / Variant / Splice variant / Isoform / Sphere / HES1 / CLAUDIN-2 / 肝細胞癌 / Claudin-2 / PPARgamma / SOD / cell cycle / PPAR γ / angiogenesis / 増殖抑制 / PGE2 / NS398 / NSAID / pRb / 細胞周期 / 血管新生 / Notch / 癌幹細胞 / リン酸化 / HIF / TCF / 低酸素 / 肝臓学 / PBC / DNA断片化 / ウルソデオキシコール酸 / Bcl-2 / アポトーシス / 原発性胆汁性肝硬変 … More Except Principal Investigator ATP7B / 肝細胞 / 肝細胞癌 / PYY_<3-36> / NASH / insulin receptor substrate / ChREBP / Wilson disease / ウイルソン病 / 銅 / 脂肪肝 / IL-1 / COX2 / in situ hybridization / 肝再生 / VEGF / 血管新生抑制 / 混合型肝癌 / claudin / 核酸アプタマー / Germ free / サイトカイン / ケモカイン / リンパ球 / 血管新生阻害剤 / 腫瘍免疫 / シンバイオティックス / 抗腫瘍効果 / 免疫チェックポイント阻害剤 / 腸内細菌叢 / 細胞療法 / 肝硬変 / iPS細胞 / ペプチドハイドロゲル / Oxidative stress / Fatty liver / 酸化ストレス / HepG2 cell / diabetes mellitus / insulin receptor / gene mutation / insulin secretion / INS-1 cell / luciferase reporter assay / InsZ / 遺伝子導入 / インスリンプロモータ領域 / siRNA / 細胞内局在変化 / Nuclear localization signal / INS-1細胞 / 2型糖尿病 / 2 / insulin receptor substrate 1 / リン酸化 / HepG2細胞 / 糖尿病 / インスリン受容体 / 遺伝子変異 / インスリン分泌 / INS-1 / Inclusion body / Mallory body / Cooper / プロテアソーム / ユビキチン / 中間径フィラメント / プロテアソームゴルジ装置 / aggresome / マロリー体 / 中間系線維 / 細胞内凝集体 / Mallory体 / hepatocytes / copper / bile / 胆汁 / ウィルソン病 / HEPATITIS C VIRUS / LIPOMICS / DEDIFFERENTIATION / PPAR α ACTIVATOR / HEPATOMA CELL / HEPATIC STELLATE CELL / フィノフィブレート / PPARγ / 肝細胞脂肪変性 / 肝発癌 / transgenic mouse / HCV-Core蛋白 / フェノフィブレート / PPARα / C型肝炎ウイルス / Lipomics / 脱分化 / PPARα activator / 肝癌細胞 / 肝星細胞 / sinusoidal endothelial cell / Hepatocyte / Liver regeneration / 劇症肝炎 / 激症肝炎 / 血管内皮増殖因子 / 免疫組織化学 / 類洞内皮細胞 / 血管内皮細胞 / マイクロＲＮＡ / 血管新生 / マイクロRNA / 血管新生抑制療法 / 内皮細胞 / 遺伝子診断・治療 / ドラッグデリバリー / 分子標的 / がん / 脳腫瘍 / 胆管がん / 膵がん / 腫瘍 / ペプチド Less

Development of aptamers targeting cell adhesion factors characteristically highly expressed in "combined hepatocellular-cholangiocarcinoma" and evaluation of their anti-tumour effects
- Principal Investigator
  
  本田健
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kurume University
Elucidation of Wnt5a-mediated immune evasion mechanisms in hepatocellular carcinoma and their application to combined immunotherapyPrincipal Investigator
- Principal Investigator
  
  古賀浩徳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
Exploring Liver Cancer-Specific Wnt Signaling Abnormalities by High-precision Analysis of TCF-4 Isoform ExpressionsPrincipal Investigator
- Principal Investigator
  
  Koga Hironori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kurume University
The investigation of factors influencing on therapeutic effect of anti-PD-1 antibody therapy for hepatocellular carcinoma by comprehensive analysis of intestinal flora
- Principal Investigator
  
  Torimura Takuji
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kurume University
Regulation of Features of Liver Cancer Stem-like Cells through the TCF-4/CLAUDIN-2/HES1 AxisPrincipal Investigator
- Principal Investigator
  
  Koga Hironori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Fundamental research for the development of an efficient hepatic regenerative cell therapy using self-assembling peptide hydrogel
- Principal Investigator
  
  Nakamura Toru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Molecular switch for WNT5A/B expression through TCF-4 isoforms in human liver cancer cellsPrincipal Investigator
- Principal Investigator
  
  Koga Hironori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Development of tumor targeting technology in combination of tumor-homing peptide and nanoparticles
- Principal Investigator
  
  Kondo Eisaku
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Niigata University
  愛知県がんセンター(研究所)
Development of new antiangiogenic therapy specific for tumor tissue of hepatocellular carcinoma with microRNA
- Principal Investigator
  
  Torimura Takuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Human T-Cell factor-4 isoform promotes tumorigenicity in a hypoxia-dependent mannerPrincipal Investigator
- Principal Investigator
  
  KOGA Hironori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Research for usefulness of intestinal peptide, PYY_<3-36> for therapeutic agents of fatty liver and NASH
- Principal Investigator
  
  UENO Takato
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
Chemotherapeutic Effect of Cell-cycle Modulation in Skp2-targeting Strategy for Liver CancerPrincipal Investigator
- Principal Investigator
  
  KOGA Hironori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
BIOLOGICAL ROLES OF NEW TRANSCRIPTION FACTOR FOR GLUCOSE METABOLISM(ChREBP) IN PANCREATIC ISLET CELLS
- Principal Investigator
  
  KAWAGUCHI Takumi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  KURUME UNIVERSITY SCHOOL OF MEDICINE
Biological significance of the expression of a Wilson disease mutant protein
- Principal Investigator
  
  HARADA Masaru
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
ROLE OF PPARα HUMAN HEPATIC STELLATE CELL AND HEPATOMA CELL
- Principal Investigator
  
  UENO Takato
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KURUME UNIVERSITY
Intracellular localization of Wilson disease protein(ATP7B), a copper-transporting ATPase.
- Principal Investigator
  
  HARADA Masaru
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University school of Medicine
Induction of apoptosis and inhibition of angiogenesis by COX-2 inhibitors in hepatocellular carcinomasPrincipal Investigator
- Principal Investigator
  
  KOGA Hironori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University School of Medicine
ウルソデオキシコール酸は原発性胆汁性肝硬変症肝のアポトーシスを制御しうるかPrincipal Investigator
- Principal Investigator
  
  古賀浩徳
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Kurume University
VEGF can be a vulnerable candidate as a therapeutic agents for severe and fulminant hepatitis?
- Principal Investigator
  
  SAKISAKA Shotaro
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Fukuoka University
  Kurume University

[Journal Article] Tumor-derived insulin-like growth factor-binding protein-1 contributes to resistance of hepatocellular carcinoma to tyrosine kinase inhibitors. Cancer Communications.2023
- Author(s)
  Suzuki H, Iwamoto H, Seki T, Nakamura T, Masuda A, Sakaue T, Tanaka T, Imamura Y, Niizeki T, Nakano M, Shimose S, Shirono T, Noda Y, Kamachi N, Sakai M, Morita K, Nakayama M, Yoshizumi T, Kuromatsu R, Yano H, Cao Y, Koga H, Torimura T.
- Journal Title
  
  Cancer Communications.
  
  Volume: 43 Issue: 4 Pages: 415-434
- DOI
  10.1002/cac2.12411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] The Beneficial Impact of MAFLD on Lenvatinib Treatment in Patients with Non-viral Hepatocellular Carcinoma.2023
- Author(s)
  Shimose S, Hiraoka A, Casadei-Gardini A, Tsutsumi T, Nakano D, Iwamoto H, Tada F, Rimini M, Tanaka M, Torimura T, Suga H, Ohama H, Burgio V, Niizeki T, Moriyama E, Suzuki H, Shirono T, Noda Y, Kamachi N, Nakano M, Kuromatsu R, Koga H, Kawaguchi T.
- Journal Title
  
  Hepatology Research.
  
  Volume: 53 Issue: 2 Pages: 104-115
- DOI
  10.1111/hepr.13843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Efficacy of Lenvatinib Combined with Transcatheter Intra-Arterial Therapies for Patients with Advanced-Stage of Hepatocellular Carcinoma: A Propensity Score Matching.2023
- Author(s)
  Shimose S, Iwamoto H, Niizeki T, Tanaka M, Shirono T, Moriyama E, Noda Y, Nakano M, Suga H, Kuromatsu R, Torimura T, Koga H, Kawaguchi T.
- Journal Title
  
  International journal of molecular sciences.
  
  Volume: 24 Issue: 18 Pages: 13715-13715
- DOI
  10.3390/ijms241813715
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Anti-PD-L1 antibodies promote cellular proliferation by activating the PD-L1-AXL signal relay in liver cancer cells2023
- Author(s)
  Tanaka T, Koga H, Suzuki H, Iwamoto H, Sakaue T, Masuda A, Nakamura T, Akiba J, Yano H, Torimura T, Kawaguchi T.
- Journal Title
  
  Hepatol Int.
  
  Volume: 8 Issue: 3 Pages: 984-997
- DOI
  10.1007/s12072-023-10572-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Clinical practice guidelines and real-life practice in hepatocellular carcinoma: A Japanese perspective2023
- Author(s)
  Koga Hironori、Iwamoto Hideki、Suzuki Hiroyuki、Shimose Shigeo、Nakano Masahito、Kawaguchi Takumi
- Journal Title
  
  Clinical and Molecular Hepatology
  
  Volume: 29 Issue: 2 Pages: 242-251
- DOI
  10.3350/cmh.2023.0102
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08345
[Journal Article] Kurume Med J.2023
- Author(s)
  Goto Y, Niizeki T, Fukutomi S, Shirono T, Shimose S, Iwamoto H, Kojima S, Kanno H, Uchino Y, Sasaki S, Shirahama N, Muroya D, Nomura Y, Akashi M, Nakayama G, Hirakawa Y, Sato T, Yoshitomi M, Sakai H, Hisaka T, Kakuma T, Koga H, Torimura T, Akagi Y, Okuda K.
- Journal Title
  
  Kurume Med J.
  
  Volume: 68 Pages: 239-245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Durable complete response is achieved by balloon-occluded transcatheter arterial chemoembolization for hepatocellular carcinoma.2022
- Author(s)
  Shirono T, Iwamoto H, Niizeki T, Shimose S, Kajiwara A, Suzuki H, Kamachi N, Noda Y, Okamura S, Nakano M, Kuromatsu R, Murotani K, Koga H, Torimura T.
- Journal Title
  
  Hepatology Communications.
  
  Volume: 6 Issue: 9 Pages: 2594-2604
- DOI
  10.1002/hep4.2016
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] The Clinical Impact of Hepatic Arterial Infusion Chemotherapy New-FP for Hepatocellular Carcinoma with Preserved Liver Function.2022
- Author(s)
  Iwamoto H, Niizeki T, Nagamatsu H, Ueshima K, Tani J, Kuzuya T, Kasai K, Kooka Y, Hiraoka A, Sugimoto R, Yonezawa T, Tanaka S, Deguchi A, Shimose S, Shirono T, Sakai M, Suzuki H, Moriyama E, Koga H, Torimura T, Kawaguchi T, New Fp Study Group, Kurume Liver Cancer Study Group of Japan.
- Journal Title
  
  Cancers.
  
  Volume: 14 Issue: 19 Pages: 4873-4873
- DOI
  10.3390/cancers14194873
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Deterioration of liver function and aging disturb sequential systemic therapy for unresectable hepatocellular carcinoma.2022
- Author(s)
  Shimose S, Hiraoka A, Tanaka M, Iwamoto H, Tanaka T, Noguchi K, Aino H, Yamaguchi T, Itano S, Suga H, Niizeki T, Moriyama E, Shirono T, Noda Y, Kamachi N, Okamura S, Nakano M, Kawaguchi T, Kuromatsu R, Koga H, Torimura T.
- Journal Title
  
  Scientific Reports.
  
  Volume: 12 Issue: 1 Pages: 17018-17018
- DOI
  10.1038/s41598-022-21528-2
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Beyond management to conquer life-threatening tumor thrombosis in hepatocellular carcinoma2022
- Author(s)
  Koga Hironori
- Journal Title
  
  Hepatobiliary Surgery and Nutrition
  
  Volume: 11 Issue: 5 Pages: 773-774
- DOI
  10.21037/hbsn-22-365
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08345
[Journal Article] Initial Experience of Atezolizumab Plus Bevacizumab for Unresectable Hepatocellular Carcinoma in Real-World Clinical Practice2021
- Author(s)
  Iwamoto H, Shimose S, Noda Y, Shirono T, Niizeki T, Nakano M, Okamura S, Kamachi N, Suzuki H, Sakai M, Kajiwara A, Itano S, Tanaka M, Yamaguchi T, Kuromatsu R, Koga H, Torimura T andon behalf of The Kurume Liver Cancer Study Group of Japan
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 11 Pages: 2786-2786
- DOI
  10.3390/cancers13112786
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Clinical Importance of Regimens in Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma with Macrovascular Invasion2021
- Author(s)
  Niizeki T, Iwamoto H, Shirono T, Shimose S, Nakano M, Okamura S, Noda Y, Kamachi N, Hiroyuki S, Sakai M, Kuromatsu R, Koga H and Torimura T
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 17 Pages: 4550-4550
- DOI
  10.3390/cancers13174450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] "First-line sorafenib sequential therapy and liver disease etiology for unresectable hepatocellular carcinoma using inverse probability weighting: A multicenter retrospective study "2021
- Author(s)
  Shimose S, Hiraoka A, Nakano M, Iwamoto H, Tanaka M, Tanaka T, Noguchi K, Aino H, Ogata K, Kajiwara M, Itano S, Yokokura Y, Yamaguchi T, Kawano H, Matsukuma N, Suga H, Niizeki T, Shirono T, Noda Y, Kamachi N, Okamura S, Kawaguchi T, Koga H, Torimura T
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 23 Pages: 8530-8541
- DOI
  10.1002/cam4.4367
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Immunological inflammatory biomarkers as prognostic predictors for advanced hepatocellular carcinoma2021
- Author(s)
  Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H, Torimura T, Kurume Liver Cancer Study Group of Japan
- Journal Title
  
  ESMO Open
  
  Volume: 6 Issue: 1 Pages: 100020-100020
- DOI
  10.1016/j.esmoop.2020.100020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Alternating Lenvatinib and Trans-Arterial Therapy Prolongs Overall Survival in Patients with Inter-Mediate Stage HepatoCellular Carcinoma: A Propensity Score Matching Study2021
- Author(s)
  Shimose S, Iwamoto H, Tanaka M, Niizeki T, Shirono T, Noda Y, Kamachi N, Okamura S, Nakano M, Suga H, Yamaguchi T, Kawaguchi T, Kuromatsu R, Noguchi K, Koga H, Torimura T
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 1 Pages: 160-160
- DOI
  10.3390/cancers13010160
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Survival Benefit of Hepatic Arterial Infusion Chemotherapy over Sorafenib in the Treatment of Locally Progressed Hepatocellular Carcinoma2021
- Author(s)
  Iwamoto H, Niizeki T, Nagamatsu H, Shimose S, Shirono T, Nakano M, Okamura S, Noda Y, Kamachi N, Sakai M, Suzuki H, Kuromatsu R, Kawaguchi A, Koga H, Torimura T,et al.
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 4 Pages: 646-646
- DOI
  10.3390/cancers13040646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Primary Treatment with Molecular-Targeted Agents for Hepatocellular Carcinoma: A Propensity Score-matching Analysis.2020
- Author(s)
  14Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H, Torimura T.
- Journal Title
  
  Hepatology Communications.
  
  Volume: 4 Issue: 8 Pages: 1218-1228
- DOI
  10.1002/hep4.1535
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Weekends-Off Lenvatinib for Unresectable Hepatocellular Carcinoma Improves Therapeutic Response and Tolerability Toward Adverse Events2020
- Author(s)
  Iwamoto Hideki、Suzuki Hiroyuki、Shimose Shigeo、Niizeki Takashi、Nakano Masahito、Shirono Tomotake、Okamura Shusuke、Noda Yu、Kamachi Naoki、Nakamura Toru、Masuda Atsutaka、Sakaue Takahiko、Tanaka Toshimitsu、Nakano Dan、Sakai Miwa、Yamaguchi Taizo、Kuromatsu Ryoko、Koga Hironori、Torimura Takuji
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 4 Pages: 1010-1010
- DOI
  10.3390/cancers12041010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Indication of Suitable Transarterial Chemoembolization and Multikinase Inhibitors for Intermediate Stage Hepatocellular Carcinoma2020
- Author(s)
  Shimose S, Kawaguchi T, Iwamoto H, Niizeki T, Shirono T, Tanaka M, Koga H, Torimura T.
- Journal Title
  
  Oncol Lett.
  
  Volume: 19 Pages: 2667-2676
- DOI
  10.3892/ol.2020.11399
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Controlling Nutritional Status (CONUT) Score Is Associated With Overall Survival in Patients With Unresectable Hepatocellular Carcinoma Treated With Lenvatinib: A Multicenter Cohort Study2020
- Author(s)
  Shimose S, Kawaguchi T, Iwamoto H, Tanaka M, Miyazaki K, Ono M, Niizeki T, Shirono T, Okamura S, Nakano M, Suga H, Yamaguchi T, Yokokura Y, Noguchi K, Koga H, Torimura T.
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 4 Pages: 1076-1089
- DOI
  10.3390/nu12041076
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Direct-acting antiviral agents do not increase the incidence of hepatocellular carcinoma development: a prospective, multicenter study2019
- Author(s)
  Ide T, Koga H, Nakano M, Hashimoto S, Yatsuhashi H, Higuchi N, Nakamuta M, Oeda S, Eguchi Y, Shakado S, Sakisaka S, Yoshimaru Y, Sasaki Y, Honma Y, Harada M, Seike M, Maeshiro T, Miuma S, Nakao K, Mawatari S, Ido A, Nagata K, Matsumoto S, Takami Y, Sohda T, Kakuma T, Torimura T
- Journal Title
  
  Hepatol Int.
  
  Volume: 印刷中 Issue: 3 Pages: 293-301
- DOI
  10.1007/s12072-019-09939-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07988, KAKENHI-PROJECT-18K07945, KAKENHI-PROJECT-19K07788, KAKENHI-PROJECT-18H02798
[Journal Article] Prognostic Impact of Transcatheter Arterial Chemoembolization (TACE) Combined With Radiofrequency Ablation in Patients With Unresectable Hepatocellular Carcinoma: Comparison With TACE Alone Using Decision-Tree Analysis After Propensity Score Matching2019
- Author(s)
  Shimose S, Tanaka M, Iwamoto H, Niizeki T, Shirono T, Aino H, Noda Y, Kamachi N, Okamura S, Nakano M, Kuromatsu R, Kawaguchi T, Kawaguchi A, Koga H, Yokokura Y, Torimura T.
- Journal Title
  
  Hepatol Res.
  
  Volume: 49 Issue: 8 Pages: 919-928
- DOI
  10.1111/hepr.13348
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Journal Article] Predictors of hepatocellular carcinoma recurrence associated with the use of direct-acting antiviral agent therapy for hepatitis C virus after curative treatment: A prospective multicenter cohort study.2019
- Author(s)
  Nakano M, Koga H, Ide T, Kuromatsu R, Hashimoto S, Yatsuhashi H, Seike M, Higuchi N, Nakamuta M, Shakado S, Sakisaka S, Miuma S, Nakao K, Yoshimaru Y, Sasaki Y, Oeda S, Eguchi Y, Honma Y, Harada M, Nagata K, Mawatari S, Ido A, Maeshiro T, Matsumoto S, Takami Y, Sohda T, Torimura T
- Journal Title
  
  Cancer Med.
  
  Volume: 印刷中 Issue: 5 Pages: 2646-2653
- DOI
  10.1002/cam4.2061
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07988, KAKENHI-PROJECT-18K07945, KAKENHI-PROJECT-19K07788, KAKENHI-PROJECT-18H02798
[Journal Article] Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1.2017
- Author(s)
  Ikezono Y, Koga H, Akiba J, Abe M, Yoshida T, Wada F, Nakamura T, Iwamoto H, Masuda A, Sakaue T, Yano H, Tsuruta O, Torimura T.
- Journal Title
  
  Molecular Cancer Research
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461025
[Journal Article] Ex vivo expansion of circulating CD34+ cells enhances the regenerative effect on rat liver cirrhosis2016
- Author(s)
  Toru Nakamura, Hironori Koga, Hideki Iwamoto, Victor Tsutsumi, Yasuko Imamura, Masako Naitou, Atsutaka Masuda, Yu Ikezono, Mitsuhiko Abe, Fumitaka Wada, Takahiko Sakaue, Takato Ueno, Masaaki Ii, Cantas Alev, Atsuhiko Kawamoto, Takayuki Asahara, Takuji Torimura
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 3 Pages: 1-13
- DOI
  10.1038/mtm.2016.25
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09030, KAKENHI-PROJECT-26461025
[Journal Article] Wheat-bran autolytic peptides containing a branched-chain amino acid attenuate non-alcoholic steatohepatitis via the suppression of oxidative stress and the upregulation of AMPK/ACC in high-fat diet-fed mice.2016
- Author(s)
  Kawaguchi T, Ueno T, Nogata Y, Hayakawa M, Koga H, Torimura T
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 39 Issue: 2 Pages: 407-414
- DOI
  10.3892/ijmm.2016.2831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461025
[Journal Article] Hepatic arterial infusion chemoembolization therapy for advanced hepatocellular carcinoma: multicenter phase II study.2016
- Author(s)
  Nagamatsu H, Sumie S, Niizeki T, Tajiri N, Iwamoto H, Aino H, Nakano M, Shimose S, Satani M, Okamura S, Kuromatsu R, Matsugaki S, Kurogi J, Kajiwara M, Koga H, Torimura T.
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 77 Issue: 2 Pages: 243-250
- DOI
  10.1007/s00280-015-2892-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461025
[Journal Article] Pancreatic DCLK1 marks quiescent but oncogenic progenitors: a possible link to neuroendocrine tumors.2016
- Author(s)
  Koga H, Ikezono Y, Torimura T.
- Journal Title
  
  Stem Cell Investigation
  
  Volume: 3 Pages: 37-37
- DOI
  10.21037/sci.2016.08.03
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461025
[Journal Article] Antiangiogenic and Antitumor Activities of Aflibercept, a Soluble VEGF Receptor-1 and -2, in a Mouse Model of Hepatocellular Carcinoma.2016
- Author(s)
  Torimura T, Iwamoto H, Nakamura T, Abe M, Ikezono Y, Wada F, Sakaue T, Masuda H, Hashimoto O, Koga H, Ueno T, Yano H.
- Journal Title
  
  Neoplasia
  
  Volume: 18 Issue: 7 Pages: 413-424
- DOI
  10.1016/j.neo.2016.05.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-16K09385
[Journal Article] Alternative treatments in advanced hepatocellular carcinoma patients with progressive disease after sorafenib treatment: a prospective multicenter cohort study.2016
- Author(s)
  Nakano M, Tanaka M, Kuromatsu R, Nagamatsu H, Satani M, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Koga H, Torimura T; Kurume Liver Cancer Study Group Of Japan.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 39 Pages: 64400-64409
- DOI
  10.18632/oncotarget.10794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-16K09385
[Journal Article] Inhibition of hypoxia-inducible factor via upregulation of von Hippel-Lindau protein induces "angiogenic switch off" in a hepatoma mouse model.2015
- Author(s)
  Iwamoto H, Nakamura T, Koga H, Izaguirre-Carbonell J, Kamisuki S, Sugawara F, Abe M, Iwabata K, Ikezono Y, Sakaue T, Masuda A, Yano H, Ohta K, Nakano M, Shimose S, Shirono T, Torimura T.
- Journal Title
  
  Molecular Therapy Oncolytics
  
  Volume: 2 Pages: 15020-15020
- DOI
  10.1038/mto.2015.20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-15K07419, KAKENHI-PROJECT-25461018
[Journal Article] Sorafenib for the treatment of advanced hepatocellular carcinoma with extrahepatic metastasis: a prospective multicenter cohort study.2015
- Author(s)
  Nakano M, Tanaka M, Kuromatsu R, Nagamatsu H, Tajiri N, Satani M, Niizeki T, Aino H, Okamura S, Iwamoto H, Shimose S, Shirono T, Koga H, Torimura T; Kurume Liver Cancer Study Group of Japan.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 12 Pages: 1836-1843
- DOI
  10.1002/cam4.548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-25461018
[Journal Article] Effects of fucoidan on proliferation, AMP-activated protein kinase, and downstream metabolism- and cell cycle-associated molecules in poorly differentiated human hepatoma HLF cells.2015
- Author(s)
  Kawaguchi T, Hayakawa M, Koga H, Torimura T.
- Journal Title
  
  International Journal of Oncology
  
  Volume: 46 Issue: 5 Pages: 2216-2222
- DOI
  10.3892/ijo.2015.2928
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-25461018
[Journal Article] High expression of the putative cancer stem cell marker, DCLK1, in rectal neuroendocrine tumors.2015
- Author(s)
  Ikezono YU, Koga H, Abe M, Akiba J, Kawahara A, Yoshida T, Nakamura T, Iwamoto H, Yano H, Kage M, Sata M, Tsuruta O, Torimura T.
- Journal Title
  
  Oncology Letters
  
  Volume: 10 Issue: 4 Pages: 2015-2020
- DOI
  10.3892/ol.2015.3513
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461025, KAKENHI-PROJECT-15K19355
[Journal Article] CD34+ cell therapy is safe and effective in slowing the decline of hepatic reserve function in patients with decompensated liver cirrhosis2014
- Author(s)
  Nakamura T, Torimura T, Iwamoto H, Kurogi J, Inoue H, Hori Y, Sumie S, Fukushima N, Sakata M, Koga H, et al.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: (in press) Issue: 10 Pages: 1830-1838
- DOI
  10.1111/jgh.12622
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999, KAKENHI-PROJECT-26461025
[Journal Article] Probiotics promote rapid-turnover protein production by restoring gut flora in patients with alcoholic liver cirrhosis.2013
- Author(s)
  Koga H, Tamiya Y, Mitsuyama K, et al.（1番目）
- Journal Title
  
  Hepatol Int
  
  Volume: 7 Issue: 2 Pages: 767-774
- DOI
  10.1007/s12072-012-9408-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] Upregulation of T-cell factor-4 isoform-responsive target genes in hepatocellular carcinoma.2013
- Author(s)
  Tomimaru Y, Koga H, Yano H, et al.（2番目）
- Journal Title
  
  Liver Int
  
  Volume: 33 Issue: 7 Pages: 1100-1112
- DOI
  10.1111/liv.12188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] Metronomic chemotherapy: possible clinical application in advanced hepatocellular carcinoma2013
- Author(s)
  Torimura T, Iwamoto H, Nakamura T, Koga H, Ueno T, Kerbel RS, Sata M
- Journal Title
  
  Transl Oncol
  
  Volume: 6 Pages: 511-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461018
[Journal Article] The SxxSS motif of T-cell factor-4 isoforms modulates Wnt/β-catenin signal activation in hepatocellular carcinoma cells.2013
- Author(s)
  Tomimaru Y, Koga H, Shin TH, et al.（3番目）
- Journal Title
  
  Cancer Lett
  
  Volume: 336 Issue: 2 Pages: 359-369
- DOI
  10.1016/j.canlet.2013.03.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] 低酸素環境におけるβ-catenin-TCF-4相互作用と肝癌の悪性化2013
- Author(s)
  古賀浩徳,Kim Miran,中村徹,ほか
- Journal Title
  
  消化器内科
  
  Volume: 57 Pages: 485-490
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] Metronomic chemotherapy : possible clinical application in advanced hepatocellular carcinoma2013
- Author(s)
  Torimura T, Iwamoto H, Nakamura T, Koga H, Ueno T, Kerbel RS, Sata M.
- Journal Title
  
  Transl Oncol
  
  Volume: 6 Pages: 511-519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] T-cell factor (TCF)-4アイソフォームによる低酸素耐性と腫瘍形成能制御2013
- Author(s)
  古賀浩徳,ほか
- Journal Title
  
  消化器内科
  
  Volume: 56 Pages: 331-339
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] 妊娠中に発症し胎児に腹水を認めた自己免疫性肝炎の1例2013
- Author(s)
  伏見崇,古賀浩徳,上妻友隆,ほか
- Journal Title
  
  肝臓
  
  Volume: 54 Pages: 780-786
- NAID
  130003384488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells.2012
- Author(s)
  Koga H
- Journal Title
  
  Int J Oncol
  
  Volume: 40 Pages: 679-685
- DOI
  10.3892/ijo.2011.1237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling.2012
- Author(s)
  Koga H
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 6 Pages: e39981-e39981
- DOI
  10.1371/journal.pone.0039981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590999
[Journal Article] Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells : an implication for the anti-tumor potential of flavonoids2006
- Author(s)
  Karuppaiyah Selvendiran, Hironori Koga, et al.
- Journal Title
  
  Cancer Research 66・9
  
  Pages: 4826-4834
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590652
[Journal Article] Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells : an implication for the anti-tumor potential of flavonoids2006
- Author(s)
  Karuppaiyah Selvendiran, Hironori Koga, et al.
- Journal Title
  
  Cancer Research 66
  
  Pages: 4826-4834
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590652
[Journal Article] Degradation of tyrosine7O5-phosphorylated signal transducer and activator of transcription 3 contributes to the potent anti-tumor effect of luteolin in human hepatoma cells2005
- Author(s)
  Hironori Koga, et al.
- Journal Title
  
  Hepatology Vol.42 SUPPL
- Data Source
  KAKENHI-PROJECT-16590652
[Journal Article] Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 32004
- Author(s)
  Takumi Kawaguchi, Takafumi Yoshida, Masaru Harada, Takao Hisamoto, Yumiko Nagao, Tatsuya Ide, Eitaro Taniguchi, Hiroto Kumemura, Shinichiro Harada, Michiko Maeyama, Shinji Baba, Hironori Koga, Ryukichi Kumashiro, Takato Ueno, Hisanobu Ogata, Akihiko Yoshi
- Journal Title
  
  Am J Pathol 165
  
  Pages: 1499-1508
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590650
[Journal Article] Overexpression of peroxisome proliferators-activated receptor γ and its ligand-mediated activation restore mislocalization of p27kip1 in human hepato2004
- Author(s)
  Hironori Koga
- Journal Title
  
  Hepatology 40巻・4号(Suppl.)
- Data Source
  KAKENHI-PROJECT-16590652
[Journal Article] PPARγ依存的MAPKの活性化とp27核内蓄積2004
- Author(s)
  古賀浩徳
- Journal Title
  
  Cancer Science 95巻・Suppl.
  
  Pages: 428-428
- Data Source
  KAKENHI-PROJECT-16590652
[Presentation] T-cell factor-4 variants regulate PD-L1 expression in liver cancer cells2023
- Author(s)
  Hironori Koga, Yasuko Imamura, Toshimitsu Tanaka, Hideki Iwamoto, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Hiroyuki Suzuki, Hirohisa Yano, Takumi Kawaguchi
- Organizer
  AACR Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08345
[Presentation] アテゾリズマブ・ベバシズマブ併用療法開始早期の単球増加不良は治療効果不良を予測しうる2022
- Author(s)
  鈴木浩之、岩本英希、下瀬茂男、新関　敬、中野聖士、城野智毅、野田　悠、蒲池直紀、山口泰三、中村　徹、増田篤高、田中俊光、黒松亮子、古賀浩徳、鳥村拓司.
- Organizer
  第58回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] . 肝動注化学療法の適応～New FP 療法の CR 予測因子からの考察～.2022
- Author(s)
  新関　敬、古賀浩徳、鳥村拓司
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌のレンバチニブ薬剤耐性における癌線維芽細胞の HGF-cMET シグナルの重要性2022
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第108回日本消化器病学会総会.
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 抗PD-L1抗体による肝癌細胞増殖機構の解明.2022
- Author(s)
  田中俊光、古賀浩徳、鈴木浩之、岩本英希、阪上尊彦、増田篤高、中村徹、秋葉　純、矢野博久、鳥村拓司.
- Organizer
  第108回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Circulating IGFBP-1 provides molecular targeted agent-resistance in hepatocellular carcinoma2021
- Author(s)
  Suzuki H, Iwamoto H, Nakamura T, Masuda A, Sakaue T, Tanaka T, Niizeki T, Okamura S, Shimose S, Shirono T, Noda Y, Kamachi N, Kuromatsu R, Koga H, Torimura T
- Organizer
  JSH International Liver Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 進行肝細胞癌に対するアテゾリズマブ,ベバシズマブ併用療法の安全性と有効性の評価-多施設共同研究-2021
- Author(s)
  下瀬茂男、岩本英希、新関　敬、城野智毅、野田　悠、岡村修祐、古賀浩徳、鳥村拓司
- Organizer
  29th JDDW（第25回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 高齢者進行肝細胞癌に対するアテゾリズマブ及びベバシズマブ併用療法の使用経験2021
- Author(s)
  城野智毅、新関　敬、岩本英希、下瀬茂男、野田　悠、岡村修祐、古賀浩徳、鳥村拓司
- Organizer
  29th JDDW（第25回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] "INITIAL EXPERIENCE OF ATEZOLIZUMAB PLUS BEVACIZUMAB FOR UNRESECTABLE HEPATOCELLULAR CARCINOMA IN REAL-WORLD CLINICAL PRACTICE"2021
- Author(s)
  Iwamoto H, Shimose S, Takashi N, Noda Y, Shirono T, Nakano M, Okamura S, Kamachi N, Suzuki H, Kuromatsu R, Koga H and Torimura T
- Organizer
  The Liver Meeting Digital Experience 2021（The 72th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌に対する肝動注化学療法 New FP 療法とソラフェニブの治療成績の多施設後ろ向き比較研究2021
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Primary Treatment with Molecular-targeted Agents for Hepatocellular carcinoma: A Propensity Score-matching Analysis2021
- Author(s)
  Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H, Torimura T
- Organizer
  JSH International Liver Conference 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Wntシグナル中枢転写因子TCF-4バリアントの消化器系細胞における発現様式2021
- Author(s)
  古賀浩徳，中村徹，岩本英希，増田篤高，阪上尊彦，田中俊光，鈴木浩之，矢野博久，鳥村拓司
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08345
[Presentation] BCLC B 肝細胞癌におけるレンバチニブ療法の post-progression survival 及び post treatmentの検討2021
- Author(s)
  下瀬茂男、新関　敬、岩本英希、城野智毅、蒲池直紀、野田　悠、岡村修祐、中野聖士、黒松亮子、古賀浩徳、鳥村拓司
- Organizer
  第57回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] TACE不応肝細胞癌に対するレンバチニブ療法とrepeated TACEの有効性の比較　傾向スコアを用いて.2020
- Author(s)
  下瀬茂男、新関　敬、岩本英希、城野智毅、岡村修祐、中野聖士、高田晃男、田中正俊、古賀浩徳、鳥村拓司.
- Organizer
  28th JDDW（第24回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 造影CTにおける造影効果を含めた腫瘍因子からみたレンバチニブの治療効果について.2020
- Author(s)
  岡村修祐、下瀬茂男、新関　敬、蒲池直紀、野田　悠、城野智毅、岩本英希、中野聖士、黒松亮子、古賀浩徳、鳥村拓司.
- Organizer
  28th JDDW（第24回日本肝臓学会大会）
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Precise evaluation of TCF-4 isoform expressions in tumors derived from digestive organs2020
- Author(s)
  Hironori Koga, Tomoya Sudo, Yoshito Akagi, Hideki Iwamoto, Takahiko Sakaue, Toshimitsu Tanaka, Jun Akiba, Hirohisa Yano, Takuji Torimura
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08345
[Presentation] Wntシグナル中枢転写因子TCF-4バリアントの癌細胞における高精度発現解析2020
- Author(s)
  古賀浩徳，阪上尊彦，増田篤高，中村徹，矢野博久，鳥村拓司
- Organizer
  第52回日本臨床分子形態学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08345
[Presentation] 肝細胞癌（HCC）に対するBalloon-Occluded Transarterial Chemoembolization（B-TACE）とCoventional TACE（C-TACE）のTE4.2020
- Author(s)
  城野智毅、新関　敬、岩本英希、下瀬茂男、蒲池直紀、野田　悠、岡村修祐、中野聖士、黒松亮子、古賀浩徳、鳥村拓司.
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] 肝細胞癌に対する血管新生阻害剤の正常臓器血管への影響と癌血管特異的遺伝子の探索2020
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Involvement of WNT Signaling in Two-faced Actions of Claudin-2 in Liver Cancer Cells2019
- Author(s)
  Koga H, Imamura Y, Nakamura T, Iwamoto H, Sakaue T, Masuda A, Tanaka T, Nakano D, Suzuki H, Yano H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Involvement of Wnt Signaling in Two-faced Actions of Claudin-2 in Liver Cancer Cells2019
- Author(s)
  Hironori Koga, Yasuko Imamura, Toru Nakamura, Hideki Iwamoto, Takahiko Sakaue, Atsutaka Masuda, Toshimitsu Tanaka, Dan Nakano, Hiroyuki Suzuki, Hirohisa Yano, Takuji Torimura
- Organizer
  AASLD 2019 “The Liver Meeting”
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] Two-faced effects of Claudin-2 on Wnt signaling in liver cancer cells2019
- Author(s)
  Hironori Koga, Hideki Iwamoto, Takahiko Sakaue, Takuji Torimura
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] Prognostic Indication of Transarterial Chemoembolization and Multikinase Inhibitors in Patients with Intermediate Stage Hepatocellular Carcinoma2019
- Author(s)
  Shimose S, Kawaguchi T, Iwamoto H, Niizeki T, Shirono T, Tanaka M, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] A Comparative Study of Necrosis-inducing Effect on Hepatocellular Carcinoma: Balloon-Occluded VS. Conventional Transcatheter Arterial2019
- Author(s)
  Shirono T, Iwamoto H, Niizeki T, Shimose S, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Real World Evidence of Lenvatinib in Adavanced Hepatocellular Carcinoma: A Multicenter Cohort Study2019
- Author(s)
  Nakano M, Kuromatsu R, Niizeki T, Okamura S, Iwamoto H, Shimose S, Shirono T, Noda Y, Kamachi N, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] Lenvatinib Alters Tumor Immune Microenvironment from ‘COLD’ TO ‘HOT’ in Hepatocellular Carcinoma2019
- Author(s)
  Suzuki H, Iwamoto H, Tanaka T, Sakaue T, Masuda A, Nakamura T, Koga H and Torimura T
- Organizer
  The 70th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07788
[Presentation] The Wnt target CLAUDIN-2 regulates tumorigenesis and stemness in human liver cancer cells2018
- Author(s)
  Hironori Koga, Fumitaka Wada, Mitsuhiko Abe, Hideki Iwamoto, Toru Nakamura, Takahiko Sakaue, Atsutaka Masuda, Toshimitsu Tanaka, Hirohisa Yano and Takuji Torimura
- Organizer
  The 109th Annual Meeting of the American Association for Cancer Research (AACR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] Claudin-2 Activates LKB1-AMPK Signals, Thereby Inducing Cell-Cycle Arrest and Autophagy in Liver Cancer Cells2018
- Author(s)
  Hironori Koga, Yasuko Imamura, Fumitaka Wada, Mitsuhiko Abe, Hideki Iwamoto, Toru Nakamura, Takahiko Sakaue, Atsutaka Masuda, Toshimitsu Tanaka, Hirohisa Yano, Takuji Torimura
- Organizer
  The 69th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] Claudin-2 activates LKB1-AMPK signals, thereby inducing cellcycle arrest and autophagy in liver cancer cells2018
- Author(s)
  Hironori Koga, Fumitaka Wada, Takahiko Sakaue, Hideki Iwamoto,Mitsuhiko Abe, Takuji Torimura
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] The Wnt Target Gene CLAUDIN-2 Regulates Tumorigenesis of Combined Hepatocellular-Cholangiocarcinoma Cells2017
- Author(s)
  Hironori Koga, Yasuko Imamura, Fumitaka Wada, Yu Ikezono, Mitsuhiko Abe, Hideki Iwamoto, Toru Nakamura, Takahiko Sakaue, Atsutaka Masuda, Toshimitsu Tanaka, Hirohisa Yano, Takuji Torimura
- Organizer
  The Liver Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] HES1 critically regulates sphere-forming ability and tumorigenesis in WNT signal-engineered liver cancer cells2017
- Author(s)
  Hironori Koga, Toru Nakamura, Fumitaka Wada, Hideki Iwamoto, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Mitsuhiko Abe, Jun Akiba, Hirohisa Yano, Takuji Torimura
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09445
[Presentation] 肝硬変に対する末梢血CD34陽性細胞を用いた新たな治療法の開発2017
- Author(s)
  中村徹、古賀浩徳、増田篤高、岩本英希、和田史孝、安倍満彦、鳥村拓司
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-15K09030
[Presentation] 自家末梢血CD34陽性細胞を用いた肝再生治療開発の臨床研究2017
- Author(s)
  中村徹、古賀浩徳、鳥村拓司
- Organizer
  第25回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-15K09030
[Presentation] Long term outcome of autologous G-CSF mobilized PB-CD34+ cell therapy in patients with decompensated liver cirrhosis2016
- Author(s)
  Toru Nakamura, Hironori Koga, Hideki Iwamoto, Atsutaka Masuda, Yu Ikezono, Fumitaka Wada, Takahiko Sakaue, Toshimitsu Tanaka, Mitsuhiko Abe, Takato Ueno, Takuji Torimura
- Organizer
  67th AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES
- Place of Presentation
  ボストン
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09030
[Presentation] 培養CD34+細胞を用いた肝硬変に対する肝再生治療2016
- Author(s)
  中村徹、古賀浩徳、増田篤高、岩本英希、池園友、和田史孝、阪上尊彦、上野隆登、鳥村拓司
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K09030
[Presentation] Regulation of Hes1 expression by the Wnt transcription factor T-cell factor-42016
- Author(s)
  Koga H, Imamura Y, Ikezono Y, Wada F, Nakamura T, Iwamoto H, Masuda A, Sakaue T, Yano H, Torimura T.
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  ニューオーリンズ
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] 培養CD34+細胞を用いた免疫不全ラット肝硬変モデルに対する細胞療法の肝線維化改善促進の機序解明2016
- Author(s)
  中村徹、古賀浩徳、増田篤高、岩本英希、池園友、和田史孝、阪上尊彦、田中俊光、上野隆登、鳥村拓司
- Organizer
  第48回日本臨床分子形態学会総会
- Place of Presentation
  熊本
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15K09030
[Presentation] 幹細胞未分化状態維持因子Hes1はNotchおよびWntからのdual regulationを受ける2016
- Author(s)
  古賀浩徳，矢野博久，鳥村拓司
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] 培養CD34+細胞を用いた細胞移植療法による肝線維化改善促進の機序解明2016
- Author(s)
  中村徹、古賀浩徳、増田篤高、岩本英希、池園友、和田史孝、阪上尊彦、上野隆登、鳥村拓司
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  幕張
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K09030
[Presentation] TCF-4 isoform upregulates CLAUDIN-2, thereby activating NOTCH signaling in human liver cancer cells2016
- Author(s)
  Koga H, Wada F, Akiba J, Ikezono Y, Iwamoto H, Nakamura T, Masuda A, Sakaue T, Yano H, Torimura T.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] Wnt下流分子Claudin-2による肝癌Notchシグナルの制御2016
- Author(s)
  古賀浩徳，矢野博久，鳥村拓司
- Organizer
  第29回日本バイオセラピィ学会学術集会総会
- Place of Presentation
  久留米
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] TCF-4の構造的差異による肝癌細胞stemness形質の制御2015
- Author(s)
  古賀浩徳、Jack R. Wands、鳥村拓司
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] The SxxSS motif of T-cell Factor-4 isoforms regulatesWnt5a expression and EMT in human liver cancer cells2015
- Author(s)
  Koga H, Nakamura T, Abe M, Ikezono Yu, Wada F, Iwamoto H, Sakaue T, Yano H, Torimura T
- Organizer
  APPLE 2015
- Place of Presentation
  大阪市
- Year and Date
  2015-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] Expression of HES1, a Notch regulator of biliary features, is regulated by T-cell factor-4 isoforms2015
- Author(s)
  Koga H, Yano H, Torimura T
- Organizer
  第23回J DDW
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25461018
[Presentation] The SxxSS motif of T-cell factor-4 isoforms regulates Wnt5a expression and EMT in human liver caner cells2015
- Author(s)
  Koga H, Nakamura T, Abe M, Ikezono Y, Wada F, Torimura T et al.
- Organizer
  第106回アメリカ癌学会
- Place of Presentation
  フィラデルフィア
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461018
[Presentation] T-cell Factor-4 isoforms participate in EMT through Wnt5a induction in human liver cancer cells2015
- Author(s)
  Koga H, Nakamura T, Abe M, Ikezono Yu, Wada F, Iwamoto H, Sakaue T, Yano H, Torimura T
- Organizer
  UEGW 2015
- Place of Presentation
  バルセロナ
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] Expression of HES1, a Notch regulator of biliary features, is regulated by T-cell factor-4 isoforms2015
- Author(s)
  Koga H, Yano H, Torimura T
- Organizer
  JDDW 2015
- Place of Presentation
  東京都（品川）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] The SxxSS motif of T-cell Factor-4 isoforms regulates Wnt5a expression and EMT in human liver cancer cells2015
- Author(s)
  Koga H, Nakamura T, Abe M, Ikezono Y, Wada F, Yano H, Torimura T.
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  フィラデルフィア
- Year and Date
  2015-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] 肝癌における血管新生の重要性2015
- Author(s)
  岩本英希、古賀浩徳、鳥村拓司
- Organizer
  第47回日本臨床分子形態学会総会･学術集会
- Place of Presentation
  長崎
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-25461018
[Presentation] The Wnt signal transcription factor TCF-4 directly regulates Bcl-xL expression in human hepatocellular carcinoma cells2014
- Author(s)
  Hironori Koga, Miran Kim, Anna Nakamura, Hirohisa Yano, Mitsuhiko Abe, Yu Ikezono, Toru Nakamura, Takuji Torimura, Jack R. Wands, and Michio Sata
- Organizer
  AACR 2014
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] Wntシグナル転写因子TCF-4 isoformによる細胞機能調節機構2014
- Author(s)
  古賀浩徳、中村徹、安倍満彦、池園友、和田史孝、矢野博久、鳥村拓司
- Organizer
  第46回日本臨床分子形態学会総会・学術集会（シンポジウム2）
- Place of Presentation
  TKP市ヶ谷カンファレンスセンター，東京
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] The Wnt signal transcription factor TCF-4 directly regulates Bcl-xL expression in human hepatocellular carcinoma cells2014
- Author(s)
  Hironori Koga
- Organizer
  AACR 2014
- Place of Presentation
  San Diego
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] The SxxSS motif of TCF-4 isoforms regulates non-canonical Wnt signaling in liver cancer cells2014
- Author(s)
  Hironori Koga, Miran Kim, Toru Nakamura, Mitsuhiko Abe, Yu Ikezono, Fumitaka Wada, Osamu Hashimoto, Hirohisa Yano, Jack R. Wands, Takuji Torimura
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜，神奈川県横浜市
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26461025
[Presentation] Wntシグナル転写因子TCF-4によるBcl-xL発現の転写レベル調節機構2013
- Author(s)
  古賀浩徳
- Organizer
  日本臨床分子形態学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] NAFLD患者におけるsmall-dense LDLコレステロール解析の意義2013
- Author(s)
  古賀浩徳
- Organizer
  第40回日本肝臓学会西部会
- Place of Presentation
  岐阜市
- Year and Date
  2013-12-06
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] TCF-4 directly regulates Bcl-xL expression in liver cancer cells2013
- Author(s)
  Hironori Koga
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2013-10-04
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] NAFLD患者におけるリポ蛋白粒子サイズの検討2013
- Author(s)
  古賀浩徳
- Organizer
  JDDW 2013
- Place of Presentation
  東京
- Year and Date
  2013-10-10
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] T-cell factor-4 isoforms directly regulate Bcl-xL expression in human hepatocellular carcinoma cells2013
- Author(s)
  Hironori Koga
- Organizer
  ASLD The Liver Meeting 2013
- Place of Presentation
  Washington D.C.
- Year and Date
  2013-11-05
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] NAFLD患者におけるsmall-dense LDLコレステロール解析の意義2013
- Author(s)
  古賀浩徳
- Organizer
  第40回日本肝臓学会西部会
- Place of Presentation
  岐阜市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナルと肝癌2013
- Author(s)
  古賀浩徳
- Organizer
  第49回肝形態科学研究会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] T-cell Factor-4 isoforms directly regulate Bcl-xL expression in human hepatocellular carcinoma (HCC) cells2013
- Author(s)
  Koga H
- Organizer
  AASLD The Liver Meeting 2013
- Place of Presentation
  Washington D.C.
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナル転写因子TCF-4によるBcl-xL発現の転写レベル調節機構2013
- Author(s)
  古賀浩徳
- Organizer
  第45回日本臨床分子形態学会総会・学術集会
- Place of Presentation
  福岡市
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Drug resistance as a function of human T-cell Factor-4 isoform expression in hepatocellular carcinoma cells2013
- Author(s)
  Hironori Koga
- Organizer
  AACR 2013
- Place of Presentation
  Washington D.C.
- Year and Date
  2013-04-07
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] アルコール性肝硬変に対するプロバイオティクスの効果2013
- Author(s)
  古賀浩徳
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2013-06-06
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナル転写因子TCF-4のアイソフォームにおける構造機能相関2013
- Author(s)
  古賀浩徳
- Organizer
  第15回　Liver Forum in Kyoto
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナル転写因子TCF-4のアイソフォームにおける構造機能相関2013
- Author(s)
  古賀浩徳
- Organizer
  第15回Liver Forum in Kyoto
- Place of Presentation
  京都市
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] NAFLD患者における脂質粒子サイズの検討2013
- Author(s)
  古賀浩徳
- Organizer
  第101回日本消化器病学会九州支部例会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] NAFLD患者における脂質粒子サイズの検討2013
- Author(s)
  古賀浩徳
- Organizer
  第101回日本消化器病学会九州支部例会
- Place of Presentation
  北九州市
- Year and Date
  2013-06-21
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Probiotics promote rapid-turnover protein production by restoring gut flora in patients with alcoholic liver cirrhosis2013
- Author(s)
  Hironori Koga
- Organizer
  APASL 2013
- Place of Presentation
  Singapore
- Year and Date
  2013-06-09
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] アルコール性肝硬変に対するプロバイオティクスの効果2013
- Author(s)
  古賀浩徳
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Probiotics promote rapid-turnover protein production by restoring gut flora in patients with alcoholic liver cirrhosis2013
- Author(s)
  Koga H
- Organizer
  APASL
- Place of Presentation
  Singapore
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] TCF-4 directly regulates Bcl-xL expression in liver cancer cells.2013
- Author(s)
  Koga H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナルと肝癌2013
- Author(s)
  古賀浩徳
- Organizer
  第49回肝形態科学研究会
- Place of Presentation
  東京
- Year and Date
  2013-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Drug resistance as a function of human T-cell Factor-4 isoform expression in hepatocellular carcinoma cells2012
- Author(s)
  Hironori Koga
- Organizer
  AASLD The Liver Meeting 2012
- Place of Presentation
  Boston
- Year and Date
  2012-11-11
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Thiazolidinediones augment anticancer effects of gemcitabine on human pancreatic cancer cells through PPARγactivation2012
- Author(s)
  Hironori Koga
- Organizer
  AACR 2012
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] T-cell Factor-4 isoforms regulate drug resistance involving upregulation of Bmi-1 in hepatocellular carcinoma cells2012
- Author(s)
  Koga H
- Organizer
  第71回　日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] TCF-4アイソフォームは抗癌剤耐性形質を制御する2012
- Author(s)
  古賀浩徳
- Organizer
  第20回浜名湖シンポジウム
- Place of Presentation
  浜松市
- Year and Date
  2012-12-23
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナルと低酸素ニッチの接点:T-cell factor-4 isoformは特異的モチーフ依存性にHIF-α分解を制御する2012
- Author(s)
  古賀浩徳
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] TCF-4アイソフォームは抗癌剤耐性形質を制御する2012
- Author(s)
  古賀浩徳
- Organizer
  第20回　浜名湖シンポジウム
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] T-cell Factor-4 isoforms regulate drug resistance involving upregulation of Bmi-1 in hepatocellularcarcinoma cells2012
- Author(s)
  Hironori Koga
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナルと低酸素ニッチの接点：T-cell factor-4 isoformは特異的モチーフ依存性にHIF-α分解を制御する2012
- Author(s)
  古賀浩徳
- Organizer
  第48回　日本肝臓学会総会
- Place of Presentation
  金沢市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] 低酸素環境におけるβ-catenin-TCF-4相互作用と肝癌の悪性化2012
- Author(s)
  古賀浩徳
- Organizer
  JDDW 2012
- Place of Presentation
  神戸市
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナル転写因子T-cell factor-4は抗癌剤耐性を制御する2012
- Author(s)
  古賀浩徳
- Organizer
  第44回　日本臨床分子形態学会総会・学術集会
- Place of Presentation
  高知市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] 低酸素環境における β-catenin-TCF-4相互作用と肝癌の悪性化2012
- Author(s)
  古賀浩徳
- Organizer
  JDDW 2012
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Wntシグナル転写因子T-cell factor-4は抗癌剤耐性を制御する2012
- Author(s)
  古賀浩徳
- Organizer
  第44回日本臨床分子形態学会総会・学術集会
- Place of Presentation
  高知市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Loss of SxxSS motif in TCF-4 Isoform Confers Tumorigenic Potential to Hepatocellular Carcinoma Upregulating HIF-2α2011
- Author(s)
  Hironori Koga, Orkhontuya Tsedensodnom, Evan J. Walker, Han Chu Lee, Kang Mo Kim, Hirohisa Yano, Jack R. Wands, and Miran Kim
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] ヒトT-cell factor-4アイソフォームによる低酸素耐性:低分化癌発育のメカニズム2011
- Author(s)
  古賀浩徳、Jack R. Wands、Miran Kim
- Organizer
  第43回日本臨床分子形態学会総会・学術集会
- Place of Presentation
  高槻市
- Year and Date
  2011-09-09
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] Loss of SxxSS motif in TCF-4 Isoform Confers Tumorigenic Potential to Hepatocellular Carcinoma Upregulating HIF-2α2011
- Author(s)
  Hironori Koga, Orkhontuya Tsedensodnom, Evan J. Walker, Han Chu Lee, Kang Mo Kim, Hirohisa Yano, Jack R. Wands, Miran Kim
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] ヒト肝癌細胞由来T-cell factor-4 isoformによる低酸素耐性と腫瘍形成能制御2011
- Author(s)
  古賀浩徳、Jack R. Wands、Miran Kim
- Organizer
  JDDW 2011
- Place of Presentation
  福岡市
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] ヒトT-cell factor-4アイソフォームによる低酸素耐性：低分化癌発育のメカニズム2011
- Author(s)
  古賀浩徳、Jack R. Wands、 Miran Kim
- Organizer
  第43回日本臨床分子形態学会総会・学術集会
- Place of Presentation
  高槻市
- Data Source
  KAKENHI-PROJECT-23590999
[Presentation] 肝癌での腫瘍血管形成における骨髄細胞の関与に関する検討
- Author(s)
  鳥村拓司、上野隆登、中村　徹、古賀浩徳、安倍満彦、池園　友、増田　裕、矢野博久、佐田通夫
- Organizer
  第45回日本臨床分子形態学会総会・学術集会
- Place of Presentation
  アクロス福岡
- Data Source
  KAKENHI-PROJECT-25461018
[Presentation] A novel synthetic sulfoglycolipid sulfoqunovosylacyl-propanediol (SQAP) switches off tumor angiogenic potential of hepatocellular carcinoma through the upregulation of von hippel-lindau protein
- Author(s)
  Iwamoto H, Torimura T, Ohta K, Koga H, Nakamura T, Abe M, Masuda H, Yano H, Sata M
- Organizer
  The 48th Annual Meeting of the European Association for the Study of the Liver (EASL)
- Place of Presentation
  RAI Convention Centre（Amsterdam, The Netherlands）
- Data Source
  KAKENHI-PROJECT-25461018
[Presentation] 腫瘍von Hippel-Lindau蛋白を標的とした新規血管新生阻害剤SQAPの肝細胞癌に対する効果の基礎的検討
- Author(s)
  岩本英希、中村徹、安倍満彦、池園友、和田史孝、黒松亮子、田尻能祥、矢野博久、古賀浩徳、鳥村拓司
- Organizer
  第51回日本肝臓学会
- Place of Presentation
  熊本
- Year and Date
  2015-05-21 – 2015-05-22
- Data Source
  KAKENHI-PROJECT-25461018

1. Torimura Takuji (60197986)

# of Collaborated Projects: 5 results

# of Collaborated Products: 46 results
2. HARADA Masaru (00241175)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. NAKAMURA Toru (30341332)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
4. Takigawa Nagio (60325107)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SAKISAKA Shotaro (90158923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. UENO Takato (70176618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. HASHIMOTO Osamu (50289427)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KAWAGUCHI Takumi (00320177)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 岩本英希 (40529541)

# of Collaborated Projects: 2 results

# of Collaborated Products: 38 results
10. Kondo Eisaku (30252951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. OOISHI Masahito (80289412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SAKATA Ryuichiro (70258424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANIGUCHI Eitaro (50341318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 木村利奈 (60299518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 池園友 (10461419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. 増田篤高 (40647872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
17. 光山慶一 (20200066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 本田健 (30457311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 坂口達也 (00757031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 東元祐一郎 (40352124)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOGA Hironori 古賀 浩徳

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Elucidation of Wnt5a-mediated immune evasion mechanisms in hepatocellular carcinoma and their application to combined immunotherapyPrincipal Investigator

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Exploring Liver Cancer-Specific Wnt Signaling Abnormalities by High-precision Analysis of TCF-4 Isoform ExpressionsPrincipal Investigator

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Regulation of Features of Liver Cancer Stem-like Cells through the TCF-4/CLAUDIN-2/HES1 AxisPrincipal Investigator

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Molecular switch for WNT5A/B expression through TCF-4 isoforms in human liver cancer cellsPrincipal Investigator

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Human T-Cell factor-4 isoform promotes tumorigenicity in a hypoxia-dependent mannerPrincipal Investigator

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Chemotherapeutic Effect of Cell-cycle Modulation in Skp2-targeting Strategy for Liver CancerPrincipal Investigator

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KOGA Hironori 古賀浩徳