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fujimoto manabu  藤本 学

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… Alternative Names

FUJIMOTO Manabu  藤本 学

藤本 学  フジモト マナブ

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Researcher Number 90272591
Other IDs
External Links
Affiliation (Current) 2022: 大阪大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 大阪大学, 医学系研究科, 教授
2013 – 2018: 筑波大学, 医学医療系, 教授
2008 – 2012: Kanazawa University, 医学系, 准教授
2007: Kanazawa University, Graduate Shcool of Meclical Science, Associate Professor
2005 – 2006: Kanazawa University, School of Medicine, Associate Professor, 医学系研究科, 助教授 … More
2004: 東京大学, 医学部附属病院, 助手
2002: 国立国際医療センター, 研究所, 室長
2001: 国立国際医療センター, 研究所・細胞組織再生医学研究部, 室長
2000: 東京大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Dermatology / Biological Sciences / Basic Section 53050:Dermatology-related / Dermatology
Except Principal Investigator
Dermatology / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords
Principal Investigator
B細胞 / 免疫 / 皮膚免疫 / 自己免疫 / 膠原病 / 自己免疫疾患 / 皮膚疾患 / 細胞 / 皮膚 / 強皮症 … More / CD22 / CD19 / シグナル伝達 / Tight-skinマウス / 全身性強皮症 / CD40 / PI-3キナーゼ / Btk / タイトスキンマウス / モデル動物 / Bリンパ球 / 抗原受容体 / CD83 / 抗原提示 / MHC class II / アレルギー / 転写因子 / 転移因子 / 線維化 / 悪性腫瘍 / 皮膚生理学 / SKIN BIOLOGY / AUTOIMMUNITY / 免疫学 / T細胞 / 疾患モデル … More
Except Principal Investigator
TGF-β / CTGF / collagen / 線維化 / c-myc / コラーゲン / fibrosis / b-FGF / 繊維化 / 中和抗体 / 線維芽細胞 / モノクロナール抗体 / 皮膚生理学 / monoclonal antibody / 次世代シークエンス / 遺伝統計学 / バイオインフォマティクス Less
  • Research Projects

    (16 results)
  • Research Products

    (70 results)
  • Co-Researchers

    (21 People)
  •  Elucidation of immune and allergic disease dynamics by integrative sequencing analysis

    • Principal Investigator
      岡田 随象
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      The University of Tokyo
  •  自己抗体により規定される「4つの皮膚筋炎」病型の病態解明と特異的治療法の開発Principal Investigator

    • Principal Investigator
      藤本 学
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Osaka University
  •  Molecular mechanisms by which the immune response to dermatomyositis-specific self-antigens forms the pathology of dermatomyositisPrincipal Investigator

    • Principal Investigator
      FUJIMOTO MANABU
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Osaka University
      University of Tsukuba
  •  B cell and autoantibody in the pathogenesis of dermatomyositisPrincipal Investigator

    • Principal Investigator
      Fujimoto Manabu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Tsukuba
  •  Development of therapy for skin diseases by utilizing regulatory B cellsPrincipal Investigator

    • Principal Investigator
      Fujimoto Manabu
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      University of Tsukuba
  •  Identification of new regulatory B cell subsets suppressing fibrosisPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Manabu
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      University of Tsukuba
      Kanazawa University
  •  Molecular mechanisms of regulatory B cell inhibition on skin immunological diseasesPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Manabu
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      University of Tsukuba
      Kanazawa University
  •  Identification of marker molecules specific for regulatory B cellsPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Manabu
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  制御性B細胞の機能解析と自己免疫疾患の抑制機構Principal Investigator

    • Principal Investigator
      藤本 学
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kanazawa University
  •  Molecular mechanisms of regulatory B cells in immuno-dermatological diseasesPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Manabu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  Developmentoftherapies for autoimmune diseases by targeting B cellsignalingPrincipal Investigator

    • Principal Investigator
      FUJIMOTO Manabu
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  The inhibition by anti-CTGF antibody produced by the DNA immunization method in the cytokine induced skin fibrosis model mice

    • Principal Investigator
      TAKEHARA Kazuhiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
  •  免疫担当細胞におけるCD83の機能と皮膚疾患との関連Principal Investigator

    • Principal Investigator
      藤本 学
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Kanazawa University
      The University of Tokyo
  •  The investigation of the mechanisms of upregulated collagen production of cytokine-induced skin fibrosis model.

    • Principal Investigator
      TAKEHARA Kazuhiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      KANAZAWA UNIVERSITY
  •  CD19によるB細胞活性化シグナルの制御メカニズムPrincipal Investigator

    • Principal Investigator
      藤本 学
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  自己免疫疾患におけるB細胞のシグナル伝達異常Principal Investigator

    • Principal Investigator
      藤本 学
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Dermatology
    • Research Institution
      Research Institute, International Medical Center of Japan
      The University of Tokyo

All 2021 2019 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

  • [Book] 制御性B細胞とは, What's New in皮膚科学2012-20132012

    • Author(s)
      藤本学
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-23659544
  • [Journal Article] Immune response to dermatomyositis-specific autoantigen, transcriptional intermediary factor 1γ can result in experimental myositis.2021

    • Author(s)
      Okiyama N, Ichimura Y, Shobo M, Tanaka R, Kubota N, Saito A, Ishitsuka Y, Watanabe R, Fujisawa Y, Nakamura Y, Murakami A, Kayama H, Takeda K, Fujimoto M
    • Journal Title

      Ann Rheum Dis.

      Volume: N.A.

    • DOI

      10.1136/annrheumdis-2020-218661

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02829, KAKENHI-PROJECT-18K08263
  • [Journal Article] Distinct Histopathologic Patterns of Finger Eruptions in Dermatomyositis Based on Myositis-Specific Autoantibody Profiles.2019

    • Author(s)
      Okiyama Naoko、Yamaguchi Yukie、Kodera Masanari、Hamaguchi Yasuhito、Yokozeki Hiroo、Ishiguro Naoko、Fujimoto Manabu
    • Journal Title

      JAMA Dermatol

      Volume: 155 Pages: 1080-1080

    • DOI

      10.1001/jamadermatol.2019.1668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08263, KAKENHI-PROJECT-18H02829
  • [Journal Article] Blockade of p38 Mitogen-Activated Protein Kinase Inhibits Murine Sclerodermatous Chronic Graft-versus-Host Disease2017

    • Author(s)
      Matsushita T, Date M, Kano M, Mizumaki K, Tennichi M, Kobayashi T, Hamaguchi Y, Hasegawa M, Fujimoto M, Takehara K.
    • Journal Title

      American Journal of Pathology

      Volume: 187 Pages: 841-850

    • DOI

      10.1016/j.ajpath.2016.12.016

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04885, KAKENHI-PROJECT-26461680
  • [Journal Article] Recent advances in dermatomyositis-specific autoantibodies.2016

    • Author(s)
      Fujimoto M, Watanabe R, Ishitsuka Y, Okiyama N.
    • Journal Title

      Curr Opin Rheumatol

      Volume: 28 Pages: 636-644

    • DOI

      10.1097/bor.0000000000000329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04885, KAKENHI-PROJECT-16H06663, KAKENHI-PROJECT-15K09757
  • [Journal Article] Therapeutic Strategy for Targeting Aggressive Malignant Gliomas by Disrupting Their Energy Balance.2016

    • Author(s)
      MatsushitaT, Huu DL, Hamaguchi Y, Hasegawa M, Naka K, Hirao A, Muramatsu M, Takehara K, Fujimoto M.
    • Journal Title

      J Allergy Clin Immunol.

      Volume: 印刷中 Pages: 1170-1182

    • DOI

      10.1016/j.jaci.2015.12.1319

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PUBLICLY-15H01509, KAKENHI-PROJECT-15H02361, KAKENHI-PROJECT-15H04885, KAKENHI-PROJECT-26290038
  • [Journal Article] Enzyme-linked immunosorbent assays for detection of anti-transcriptional intermediary factor-1 gamma and anti-Mi-2 autoantibodies in dermatomyositis.2016

    • Author(s)
      Fujimoto M, Murakami A, Kurei S, Okiyama N, Kawakami A, Mishima M, Sato S, Seishima M, Suda T, Mimori T, Takehara K, Kuwana M.
    • Journal Title

      J Dermatol Sci

      Volume: 84 Pages: 272-281

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04885
  • [Journal Article] Decreased levels of regulatory B cells in patients with systemic sclerosis: association with autoantibody production and disease activity.2016

    • Author(s)
      Matsushita T, Hamaguchi Y, Hasegawa M, Takehara K, Fujimoto M.
    • Journal Title

      Rheumatology

      Volume: 55 Pages: 263-267

    • DOI

      10.1093/rheumatology/kev331

    • NAID

      120005764209

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461680, KAKENHI-PROJECT-25461686, KAKENHI-PROJECT-15H04885
  • [Journal Article] B cells promote tumor immunity against B16F10 melanoma.2014

    • Author(s)
      Kobayashi T, Hamaguchi Y, Hasegawa M, Fujimoto M, Takehara K, Matsushita T.
    • Journal Title

      Am J Pathol

      Volume: 184 Pages: 3120-3129

    • DOI

      10.1016/j.ajpath.2014.07.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25461686, KAKENHI-PROJECT-26670521
  • [Journal Article] Blockade of Syk Ameliorates the development of murine sclerodermatous chronic graft-versus-host disease2014

    • Author(s)
      Le Huu D, Kimura H, Date M, Hamaguchi Y, Hasegawa M, Hau KT, Fujimoto M, Takehara K, Matsushita T.
    • Journal Title

      J Dermatol Sci

      Volume: in press Pages: 214-21

    • DOI

      10.1016/j.jdermsci.2014.02.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659523
  • [Journal Article] Autoantibodies to RuvBL1 and RuvBL2: a novel systemic sclerosis-related antibody associated with diffuse cutaneous and skeletal muscle involvement2014

    • Author(s)
      Kaji K, Fertig N, Medsger TA Jr, Satoh T, Hoshino K, Hamaguchi Y, Hasegawa M, Lucas M, Schnure A, Ogawa F, Sato S, Takehara K, Fujimoto M, Kuwana M.
    • Journal Title

      Arthritis Care Res (Hoboken)

      Volume: 66 Pages: 575-584

    • DOI

      10.1002/acr.22163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-26461471
  • [Journal Article] Donor-derived regulatory B cells are important for suppression of murine sclerodermatous chronic graft-versus-host disease.2013

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, T akehara K, T edder TF, Fujimoto M
    • Journal Title

      Blood.

      Volume: 121 Pages: 3274-83

    • DOI

      10.1182/blood-2012-11-465658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-23791260, KAKENHI-PROJECT-24659523
  • [Journal Article] Circulating gamma/delta T cells in systemic sclerosis exhibit activated phenotype and enhance gene expression of proalpha2(I) collagen of fibroblasts2013

    • Author(s)
      Ueda-Hayakawa I, Hasegawa M, Hamaguchi Y, Takehara K, Fujimoto M.
    • Journal Title

      J Dermatol Sci

      Volume: 69 Pages: 54-60

    • DOI

      10.1016/j.jdermsci.2012.10.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659523
  • [Journal Article] FTY720 ameliorates murine sclerodermatous chronic graft-versus-host disease by promoting expansion of splenic regulatory cells and inhibiting immune cell infiltration into skin2013

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, Takehara K, Fujimoto M
    • Journal Title

      Arthritis Rheum.

      Volume: in press Pages: 1624-35

    • DOI

      10.1002/art.37933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-24659523, KAKENHI-PROJECT-25461686
  • [Journal Article] Chemokine receptors CCR2 and CX3CR1 regulate skin fibrosis in the mouse model of cytokine-induced systemic sclerosis2013

    • Author(s)
      Arai M, Ikawa Y, Chujo S, Hamaguchi Y, Ishida W, Shirasaki F, Hasegawa M, Mukaida N, Fujimoto M, Takehara K.
    • Journal Title

      J Dermatol Sci

      Volume: 69 Pages: 250-8

    • DOI

      10.1016/j.jdermsci.2012.10.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659523
  • [Journal Article] BLNK expression contributes to controlling allergic and autoimmune diseases by mediating IL-10 production in regulatory B cells.2013

    • Author(s)
      Jin G, Hamaguchi Y, Matsushita T, Hasegawa M, Huu DL, Ishiura N, Naka K, Hirao A, Takehara K, Fujimoto M
    • Journal Title

      J Allergy Clin Immunol.

      Volume: 131 Pages: 1674-1682

    • DOI

      10.1016/j.jaci.2013.01.044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-23791260
  • [Journal Article] Potential roles of interleukin-17A in the development of skin fibrosis in mice2012

    • Author(s)
      Okamoto Y, Hasegawa M, Matsushita T, Hamaguchi Y, Huu DL, Iwakura Y, Fujimoto M, T akehara K
    • Journal Title

      Arthritis Rheum.

      Volume: 64 Pages: 3726-35

    • DOI

      10.1002/art.34643

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-23591640, KAKENHI-PROJECT-24220011
  • [Journal Article] 制御性B細胞と接触過敏反応日本皮膚アレルギー学会2012

    • Author(s)
      藤本学
    • Journal Title

      接触皮膚炎学会雑誌

      Volume: 6 Pages: 55-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659544
  • [Journal Article] Basophils and mast cells play critical roles for leukocyte recruitment in IgE-mediated cutaneous reverse passive Arthus reaction2012

    • Author(s)
      Jin G, Matsushita T, Hamaguchi Y, Le H uu D, Ishii T, Hasegawa M, Obata K Kar asuyama H, Takehara K, Fujimoto M
    • Journal Title

      J.Dermato.Sci.

      Volume: 67 (3) Pages: 181-189

    • DOI

      10.1016/j.jdermsci.2012.06.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J05115, KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-24390093
  • [Journal Article] IL-6 blockade attenuates the development of murine sclerodermatous chronic graft-versus-host disease.2012

    • Author(s)
      Le Huu D, Matsushita T, Jin G, Hamaguchi Y, Hasegawa M, T akehara K, Fujimoto M
    • Journal Title

      J Invest Dermato

      Volume: 132 Pages: 2752-2761

    • DOI

      10.1038/jid.2012.226

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390281, KAKENHI-PROJECT-24659523
  • [Journal Article] 制御性B細胞と自己免疫疾患2011

    • Author(s)
      藤本学、松下貴史
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 56 Pages: 338-345

    • NAID

      40019017871

    • Data Source
      KAKENHI-PROJECT-23659544
  • [Journal Article] Regulatory B cells (B10 cells) have a suppressive role in murine lupus : CD19 and B10 cell deficiency exacerbates systemic autoimmunity.2010

    • Author(s)
      Watanabe R, Ishiura N, Nakashima H, Kuwano Y, Okochi H, Tamaki K, Sato S, Tedder TF, Fujimoto M.
    • Journal Title

      J Immunol 184

      Pages: 4801-4809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Regulatory B cells (B10 cells) have a suppressive role in murine lupus : CD19 and B10 cell deficiency exacerbates systemic autoimmunity2010

    • Author(s)
      Watanabe R, Ishiura N, Nakashima H, Kuwano Y, Okochi H, Tamaki K, Sato S, Tedder TF, Fujimoto M.
    • Journal Title

      Journal of Immunology (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Autoantibody-mediated regulation of B cell responses by functional anti-CD22 autoantibodies in patients with systemic sclerosis.2010

    • Author(s)
      Odaka M, Hasegawa M, Hamaguchi Y, Ishiura N, Kumada S, Matsushita T, Komura K, Sato S, Takehara K, Fujimoto M.
    • Journal Title

      Clin Exp Immunol. 159

      Pages: 176-184

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Inducible costimulator ligand (ICOSL) regulates bleomycin-induced lung and skin fibrosis independent of ICOS-ICOSL pathway.2010

    • Author(s)
      Tanaka C, Fujimoto M, Hamaguchi Y, Sato S, Takehara K, Hasegawa M.
    • Journal Title

      Arthritis Rheum 62

      Pages: 1723-1732

    • NAID

      10029469768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Regulatory B cells in skin and connective tissue diseases2010

    • Author(s)
      Fujimoto M.
    • Journal Title

      Journal of Dermatological Science

      Volume: 60 Pages: 1-7

    • NAID

      10027473489

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22021017
  • [Journal Article] Differential phosphorylation of functional tyrosines in CD19 modulates B lymphocyte activation.2010

    • Author(s)
      Ishiura N, Nakashima H, Watanabe R, Kuwano Y, Adachi T, Takahashi Y, Tsubata T, Okochi H, Tamaki K, Tedder TF, Fujimoto M.
    • Journal Title

      Eur J Immunol 40

      Pages: 1192-1204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions.2010

    • Author(s)
      Nakashima H, Hamaguchi Y, Watanabe R, Ishiura N, Kuwano Y, Okochi H, Takahashi Y, Tamaki K, Sato S, Tedder TF, Fujimoto M.
    • Journal Title

      J Immunol 184

      Pages: 4637-4645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Protective and pathogenic roles for B cells during systemic autoimmunity in NZB/W F1 mice.2010

    • Author(s)
      Haas KM, Watanabe R, Matsushita T, Nakashima H, Ishiura N, Okochi H, Fujimoto M, Tedder TF.
    • Journal Title

      J Immunol. 184

      Pages: 4789-4800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Establishment of experimental eosinophilic vasculitis by IgE-mediated cutaneous reverse passive Arthus reaction.2009

    • Author(s)
      Ishii T, Fujita T, Matsushita T, Yanaba K, Hasegawa M, Nakashima H, Ogawa F, Shimizu K, Takehara K, Tedder TF, Sato S, Fujimoto M.
    • Journal Title

      Am J Pathol. 174

      Pages: 2225-2233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mice models of systemic sclerosis.2009

    • Author(s)
      Hasegawa M, Matsushita Y, Horikawa M, Higashi K, Tomigahara Y, Kaneko H, Shirasaki F, Fujimoto M, Takehara K, Sato S.
    • Journal Title

      Arthritis Rheum 60

      Pages: 3465-3475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] RhoH plays critical roles in FcεRI-dependent signal transduction in mast cells.2009

    • Author(s)
      Oda H, Fujimoto M, Patrick MS, Chida D, Sato Y, Azuma Y, Aoki H, Abe T, Suzuki H, Shirai M.
    • Journal Title

      J Immunol. 182

      Pages: 957-962

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] P-selectin glycoprotein ligand-1 contributes to wound healing predominantly as a P-selectin ligand and partly as an E-selectin ligand.2009

    • Author(s)
      Tomita H, Iwata Y, Ogawa F, Komura K, Shimizu K, Yoshizaki A, Hara T, Muroi E, Yanaba K, Bae S, Takenaka M, Hasegawa M, Fujimoto M, Sato S.
    • Journal Title

      J Invest Dermatol 129

      Pages: 2059-2067

    • NAID

      120006984034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] CD19, a response regulator of B lymphocytes, regulates wound healing through hyaluronan-induced TLR4 signaling.2009

    • Author(s)
      Iwata Y, Yoshizaki A, Komura K, Shimizu K, Ogawa F, Hara T, Muroi E, Bae S, Takenaka M, Yukami T, Hasegawa M, Fujimoto M, Tomita Y, Tedder TF, Sato S.
    • Journal Title

      Am J Pathol. 175

      Pages: 649-660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] CD19 regulates skin and lung fibrosis via Toll-like receptor signaling in a model of bleomycin-induced scleroderma.2008

    • Author(s)
      Yoshizaki A, Iwata Y, Komura K, Ogawa F, Hara T, Muroi E, Takenaka M, Shimizu K, Hasegawa M, Fujimoto M, Tedder TF, Sato S.
    • Journal Title

      Am J Pathol 172

      Pages: 1650-1663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] A regulatory B cell subset with a unique CD1d^<high>CD5^+ phenotype controls T cell-dependent inflammatory responses.2008

    • Author(s)
      Yanaba K, Bouaziz J-D, Hass KM, Poe JC, Fujimoto M, Tedder TF.
    • Journal Title

      Immunity 28

      Pages: 639-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Blockade of CD40-CD40 ligand interactions attenuates skin fibrosis and autoimmunity in the tight-skin mouse.2008

    • Author(s)
      Komura K, Fujimoto M, Yanaba K, Matsushita T, Matsushita Y, Horikawa M, Ogawa F, Shimizu K, Hasegawa M, Takehara K, Sato S.
    • Journal Title

      Ann Rheum Dis 67

      Pages: 867-872

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] A regulatory B cell subset with a unique CD1dhighCD5+ phenotype controls T cell-dependent inflammatory responses2008

    • Author(s)
      Yanaba K, Bouaziz J-D, Hass KM, Poe JC, Fujimoto M, Tedder TF
    • Journal Title

      Immunity 28

      Pages: 639-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Regulatory B cells inhibit EAE initiation while other B cells promote disease progression.2008

    • Author(s)
      Matsushita T, Yanaba K, Bouaziz J-D, Fujimoto M, Tedder TF.
    • Journal Title

      J Clin Invest 118

      Pages: 3420-3430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Blockade of CD40-CD40 ligand interactions attenuates skin fibrosis and autoimmunity in the tight-skin mouse2008

    • Author(s)
      Komura K, Fujimoto M, Yanaba K, Matsushita T, Matsushita Y, Horikawa M, Ogawa F, Shimizu K, Hasegawa M, Takehara K, Sato S
    • Journal Title

      Ann Rheum Dis 67

      Pages: 867-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591339
  • [Journal Article] Neutralizing monoclonal antibody to human connective tissue growth facfor ameliorates transforming growth factor-β-induced mouse fibrosis2008

    • Author(s)
      Ikawa Y, POH-SING NG, Endo K, Kondo M, Chujo S, Ishida W, Shirasaki F, Fujimoto M, Takehara K
    • Journal Title

      J Cellular Physiol掲載(発行)確定 14(in press)

      Pages: 680-687

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Journal Article] Phase-Dependent Roles of E-selectin during Chronic Contact Hypelsensitivity Responses.2007

    • Author(s)
      Fujita T, Fujimoto M, et. al.
    • Journal Title

      Am J Pathol 170

      Pages: 1649-1658

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] CD19 expression in B cells is important for suppression of contact hypersensitivity.2007

    • Author(s)
      Watanabe R, Fujimoto M, et. al.
    • Journal Title

      Am J Pathol 171

      Pages: 560-570

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Serum chemokine profile in patients with bullous pemphigioid.2007

    • Author(s)
      Nakashima H, Fujimoto M, et. al.
    • Journal Title

      British Journal of Dermatology 156

      Pages: 454-459

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] CD19 expression in B cells is important for suppression of contact hypersensitivity2007

    • Author(s)
      Watanabe, R., Fujimoto, M., et. al.
    • Journal Title

      Am J Pathol 171

      Pages: 560-570

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] BAFF agonist attenロates the development of skin fibrosis in Thight-skin mice.2007

    • Author(s)
      Matsushita T, Fujimoto M, et. al.
    • Journal Title

      J Invest Dermatol 127

      Pages: 2772-2780

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Serum chemokine profile in patients with bullous pemphigioid2007

    • Author(s)
      Nakashima, H., Fujimoto, M., et. al.
    • Journal Title

      British Journal of Dermatology 156

      Pages: 454-459

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Phase-Dependent Roles of E-selectin during Chlonic Contact Hypelsensitivity Responses2007

    • Author(s)
      Fujita T, Fujimoto M, et. al.
    • Journal Title

      Am J Pathol 170

      Pages: 1649-1658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Identification of a novel autoantibody reactive with 155-and140-kDa nuclear proteins in patients with dermatomyositis : an association with malignancy2007

    • Author(s)
      Kaji, K., Fujimoto, M., et. al.
    • Journal Title

      Rheumatology 46

      Pages: 25-28

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Identification of a novel autoantibody reactive with 155-and 140-kDa nuclear proteins in patients with dermatomysitis : an association with malignancy.2007

    • Author(s)
      Kaji K., fujimoto M, et al.
    • Journal Title

      Rheumatology 46

      Pages: 25-28

    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Phase-Dependent Roles of E-selectin during Chronic Contact Hypersensitivity Responses2007

    • Author(s)
      Fujita, T., Fujimoto, M., et. al.
    • Journal Title

      Am J Pathol 170

      Pages: 1649-1658

    • NAID

      120001138017

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] BAFF antagonist attenuates the development of skin fibrosis om Tight-skin mice.2007

    • Author(s)
      Matsushita T, Fujimoto M, et. al.
    • Journal Title

      J Invest Dermatol 127

      Pages: 2772-2780

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Serum chemokine profile in patients with bullous pemphigioid.2007

    • Author(s)
      Nakashima H., Fujimoto M, et al.
    • Journal Title

      British Journal of Dermatology 156

      Pages: 454-459

    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] BAFF antagonist attenuates the development of skin fibrosis in Tight-skin mice2007

    • Author(s)
      Matsushita, T., Fujimoto, M., et. al.
    • Journal Title

      J Invest Dermatol 127

      Pages: 2772-2780

    • NAID

      120005756483

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] CD19 expression in B cells is important for suppression of contact hypersensitivity2007

    • Author(s)
      Watanabe R, Fujimoto M, et. al.
    • Journal Title

      Am J Pathol 171

      Pages: 560-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Identification of anovel autoantibody reactive with 155-and 140-kDa nuclear proteins in patients with dermatomyositis: an association with malignancy.2007

    • Author(s)
      Kaji K, Fujimoto M, et. al.
    • Journal Title

      Rheumatology 46

      Pages: 25-28

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] B cell antigen receptor and CD40 differentially regulate CD22 tyrosine phosphorylation.2006

    • Author(s)
      Fujimoto M, Kuwano Y, Watanabe R, Asashima N ほか
    • Journal Title

      Journal of Immunology 176・2

      Pages: 873-879

    • Data Source
      KAKENHI-PROJECT-16790623
  • [Journal Article] E-and P-synergistically inhibit bleomycin-Induced pulmonary fibrosis.2006

    • Author(s)
      Horikawa M., Fujimoto M, et al.
    • Journal Title

      American Journal of Pathology 169

      Pages: 740-749

    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] E-and P-selectins synergistically inhibit bleomycin-Induced pulmonary fibrosis.2006

    • Author(s)
      Horikawa M, Fujimoto M, et. al.
    • Journal Title

      American Journal of Pathology 169

      Pages: 740-749

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Serum levels of B cell activator of the TNF family (BAFF) are increased in bullous pemphigoid but not in pemphigus vulgaris2006

    • Author(s)
      Asashima, N., Fujimoto, M., et. al.
    • Journal Title

      British Journal of Dermatology 155

      Pages: 330-336

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] E-and P-selectins synergistically inhibit bleomycin-Induced pulmonary fibrosis2006

    • Author(s)
      Horikawa, M., Fujimoto, M., et. al.
    • Journal Title

      American Journal of Pathology 169

      Pages: 740-749

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Serum levels of B cell activator of the TNF family(BAFF) are increased in bullous pemphigoid but not in pemphigus vulgaris.2006

    • Author(s)
      Asashima N, Fujimoto M, et al.
    • Journal Title

      British Journal of Dermatology 155

      Pages: 330-336

    • Data Source
      KAKENHI-PROJECT-18591239
  • [Journal Article] Neutralizing monoclonal antibody to human connective tissue growth factor ameliorates transforming growth factor B-induced mouse fibrosis

    • Author(s)
      Ikawa, Y., POH-SING, NG, Endo, K., Kondo, M., Chujo, S., WATARU, Shirasaki, F., Fujimoto, M., Takehara, K
    • Journal Title

      Journal of Cellular Physiology (in print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Journal Article] Neutralizing monoclonal antibody to human connective tissue growth facfor ameliorates transforming growth factor-β-induced mouse fibrosis

    • Author(s)
      Ikawa Y, POH-SING NG, Endo K, Kondo M, Chujo S, Ishida W, Shirasaki F, Fujimoto M, Takehara K
    • Journal Title

      Journal of Cellular Physiology (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Presentation] Regulatory B cells in skin disease2013

    • Author(s)
      Fujimoto M
    • Organizer
      International Meeting of Investigative Dermatology
    • Place of Presentation
      Edinburgh, UK
    • Year and Date
      2013-05-10
    • Data Source
      KAKENHI-PROJECT-23390281
  • [Presentation] TGF-βで誘導されるモデルマウスの線維化が抗CTGF抗体で抑制された2007

    • Author(s)
      伊川友香, 松下幸世, 近藤美幾 藤本晃英, 長川 稔, 竹原和彦, 刀祢裕美, 和田泰三, 谷内江昭宏
    • Organizer
      第1回日本CCNファミリ-研究会
    • Place of Presentation
      岡山市
    • Year and Date
      2007-10-27
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Presentation] Neutralizing antibody to human connective tissue growth factor ameliorates transforming growth factor-β induced mouse fibrosis model2007

    • Author(s)
      Ikawa Y, Kondo M, Chujo S, Shirasaki F, Fujimoto M, Ng Poh-Sing, Takehara K
    • Organizer
      Professor E. Carwaile LeRoy Memorial International Workshop on Scleroderma
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-05-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Presentation] Neutralizing antibody to human connective tissue growth factor ameliorates transforming growth factor induced mouse fibrosis model2007

    • Author(s)
      Ikawa, Y., Ng, Poh-Sing, Miyazaki, M., Chujo, S., Ishida, W., Shirasaki, F., Fujimoto, M., Takehara, K
    • Organizer
      Japan CCN family Society
    • Place of Presentation
      Okayama
    • Year and Date
      2007-10-07
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Presentation] TGF一βで誘導されるモデルマウスの線維化が抗CTGF抗体で抑制された2007

    • Author(s)
      伊川友香, 松下幸世, 近藤美幾, 藤本晃英, 長谷川稔, 竹原和彦, 刀祢裕美, 和田泰三, 谷内江昭宏
    • Organizer
      第1回日本CCNファミリー研究会
    • Place of Presentation
      岡山市
    • Year and Date
      2007-10-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591240
  • [Presentation] Neutralizing antibody to human connective tissue growth factor ameliorates transforming growth factor-β induced mouse fibrosis model2007

    • Author(s)
      Ikawa Y, Kondo M, Chujo S, Shirasaki F, Fujimoto M, NgPoh-Sing, Takehara K
    • Organizer
      Professor E.Carwaile LeRoy Memorial International Workshop on Scleroderma
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-05-20
    • Data Source
      KAKENHI-PROJECT-18591240
  • 1.  TAKEHARA Kazuhiko (50142253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 2.  SHIRASAKI Fumiaki (10313644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  CHUJO Sonoko (20401911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  佐藤 伸一 (20215792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  岡田 随象 (70727411)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  田中 良哉 (30248562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  駒形 嘉紀 (60281995)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  奥野 龍禎 (00464248)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  熊坂 夏彦 (80525527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  王 青波 (00916033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  竹島 雄介 (70893288)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OKIYAMA Naoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 13.  MATSUSHITA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 14.  Tadokoro Yuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  Kobayashi Masahiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  Ueno Masaya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  石塚 洋典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  長谷川 稔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 19.  平尾 敦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  仲 一仁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  桑名 正隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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