TAKAKU Kazuaki 高久和明

Researcher Number	90313121
Affiliation (based on the past Project Information) *help	2001 – 2002: 京都大学, 医学研究科, 助手 2000: Department of Pharmacology, Kyoto University Graduate School of Medicine, Assistant Professor, 大学院・医学研究科, 助手 1999: 東京大学, 大学院・薬学系研究科, 助手
Review Section/Research Field	Except Principal Investigator Biological Sciences / General pharmacology
Keywords	Except Principal Investigator COX-2 / APC / ノックアウトマウス / LKB1 / トランスジェニックマウス / マイクロアレイ / LKB 1 / Pathology / Cancer / Transgenic mouse … More / Stromal cells / Prostaglandin / EP2 / PGE_2 / cPLA2 / ポリープ / β-catenin / Smad2 / 血管新生 / 肝癌 / 大腸癌 / TGF-βシグナル / 線維芽細胞 / Fhit / Lkb1 / Apc / 病理学 / 癌 / 間質細胞 / プロスタグランジン / parasympathetic nervous system / muscarinic receptor / knockout mice / acetylcholine / 副交感神経 / ムスカリン性受容体 / アセチルコリン / mPGES / LYVE-1 / リンパ管新生 / B16F10 / mTOR / Cdx2 / プロテオミクス / マクロファージ / 染色体不安定性 / Wnt / CDX2 / CCL9 / CCR1 / CXCR3 / ケモカイン / 同所移植 / 浸潤 / 転移 Less

消化器癌の転移機構とその治療の研究
- Principal Investigator
  
  TAKETO Makoto
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Kyoto University
Epithelium-stroma interactions in carcinogenesis
- Principal Investigator
  
  TAKETO Makoto Mark
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  KYOTO UNIVERSITY
Analysis of muscarinic receptor function using knockout mice
- Principal Investigator
  
  MATSUI Minoru
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  The University of Tokyo

All 2002 2000

All Journal Article

[Journal Article] No effects of Smad2 (Madh2) null mutation on malignant progression of intestinal polyps in Apc^<Δ716> knockout mice.2002
- Author(s)
  K.Takaku
- Journal Title
  
  Cancer Research 62巻・16号
  
  Pages: 4558-4561
- Data Source
  KAKENHI-PROJECT-14GS0316
[Journal Article] No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc^<Δ716> knockout mice.2002
- Author(s)
  Takaku, K et al.
- Journal Title
  
  Cancer Research 62(16)
  
  Pages: 4558-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219203
[Journal Article] No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in ApcΔ716 knockout mice.2002
- Author(s)
  Takaku, K.et al.
- Journal Title
  
  Cancer Research 62・16
  
  Pages: 4558-4561
- Data Source
  KAKENHI-PROJECT-12219203
[Journal Article] No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc^<Δ716> knockout mice.2002
- Author(s)
  Takaku K et al.
- Journal Title
  
  Cancer Research 62
  
  Pages: 4558-4561
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219203
[Journal Article] Suppression of intestinal polyposis in Apc^<Δ716> knockout mice by an additional mutation in the cytosolic phospholipase A(2) gene.2000
- Author(s)
  Takaku K et al.
- Journal Title
  
  Journal of Biological Chemistry 275
  
  Pages: 34013-34016
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219203
[Journal Article] Suppression of intestinal polyposis in ApcΔ716 knockout mice by an additional mutation in the cytosolic phospholipase A2 gene.2000
- Author(s)
  Takaku, K.et al.
- Journal Title
  
  Journal of Biological Chemistry 275・44
  
  Pages: 34013-34016
- Data Source
  KAKENHI-PROJECT-12219203
[Journal Article] Suppression of intestinal polyposis in Apc^<Δ716> knockout mice by an additional mutation in the cytosolic phospholipase A (2) gene.2000
- Author(s)
  Takaku, K et al.
- Journal Title
  
  Journal of Biological Chemistry 275(44)
  
  Pages: 34013-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219203

1. TAKETO Makoto (70281714)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. OSHIMA Masanobu (40324610)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. AOKI Masahiro (60362464)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MIYOSHI Hiroyuki (30362479)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KITAMURA Takanori (10378622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 石川智夫 (70322162)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MATSUI Minoru (50282611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SASAKI Nobuya (20302614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAKU Kazuaki 高久 和明

Research Projects

Research Products

Co-Researchers

消化器癌の転移機構とその治療の研究

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Epithelium-stroma interactions in carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of muscarinic receptor function using knockout mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] No effects of Smad2 (Madh2) null mutation on malignant progression of intestinal polyps in Apc^<Δ716> knockout mice.2002

Author(s)

Journal Title

Data Source

[Journal Article] No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc^<Δ716> knockout mice.2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in ApcΔ716 knockout mice.2002

Author(s)

Journal Title

Data Source

[Journal Article] No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc^<Δ716> knockout mice.2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] Suppression of intestinal polyposis in Apc^<Δ716> knockout mice by an additional mutation in the cytosolic phospholipase A(2) gene.2000

Author(s)

Journal Title

Description

Data Source

[Journal Article] Suppression of intestinal polyposis in ApcΔ716 knockout mice by an additional mutation in the cytosolic phospholipase A2 gene.2000

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of intestinal polyposis in Apc^<Δ716> knockout mice by an additional mutation in the cytosolic phospholipase A (2) gene.2000

Author(s)

Journal Title

Description

Data Source

TAKAKU Kazuaki 高久和明