OHMINE Ken 大嶺謙

… Alternative Names

大嶺謙オオミネケン

OHMINA Ken 大嶺謙

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Researcher Number	90316521
Other IDs
External Links
Affiliation (Current)	2025: 自治医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2017: 自治医科大学, 医学部, 准教授 2012 – 2015: 自治医科大学, 医学部, 講師 2010: 自治医科大学, 医学部, 講師 2000 – 2005: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / Tumor therapeutics / Hematology Except Principal Investigator Hematology / Hematology / Tumor therapeutics
Keywords	Principal Investigator RhoA / imatinib / ABL / BCR / glutatione / Heme / SR / KCL22 / Drug resistance / CML … More / UCN-01 / Faenesyltransferase阻害薬 / Nrf2 / グルタチオン / ヘム / KCL22SR / 薬剤耐性 / 慢性骨髄性白血病 / 細胞老化 / 細胞疲弊化 / 非ホジキンリンパ腫 / CD19抗原 / 遺伝子改変T細胞療法 / HIF-1 / H_2O_2 / L-NMMA / GATA / 転写因子 / エリスロポエチン … More Except Principal Investigator K562 / R115777 / imatinib / β-globin / RR / Tipifarnib / Drug resistance / KU812 / SR / KCL22 / RAS / 薬剤耐性 / 慢性骨髄性白血病 / 造血器腫瘍 / キメラ抗原受容体 / 免疫療法 / 遺伝子治療 / RCAN1 / Farnesyltransferase inhibitor / Heme / Imatinib / Chronic myeloid leukemia / ABL / BCR / drug resistance / CML / farnesyltransferase inhibitor / heme / K532 / fanesyltransferase inhibitor / Chronic Myelogeneous leukemia / γ-GCS / Nrf2 / ascorbic acid / STI571 / Farnesyltransferase阻害剤 / T細胞療法 / 成人T細胞白血病 / T細胞 / 免疫遺伝子療法 / 血液腫瘍学 / Tリンパ球 / 細胞療法 / U266 / 多発性骨髄腫 / NF-AT / 32D / NFAT / calcineurin / HL60 / 急性骨髄性白血病 / 癌遺伝子 / レトロウイルス / RELB / レトロウイルスライブラリー / T細胞性リンパ腫 Less

Safety and persistence of genetically modified T-cells in patients with non-Hodgkin lymphomaPrincipal Investigator
- Principal Investigator
  
  OHMINE KEN
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Jichi Medical University
Development of immunogene therapy using T-cells expressing a chimeric antigen receptor for adult T-cell leukemia
- Principal Investigator
  
  Tsukahara Tomonori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Jichi Medical University
Development of gene therapy for refractory non-Hodgkin lymphoma using T-cells expressing a chimeric antigen receptor
- Principal Investigator
  
  OZAWA keiya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Clarification of RCAN1-mediated deregulation of cellular functionsin leukemia cells
- Principal Investigator
  
  NAGAI Tadashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Identification of oncogenes in T cell lymphoma by retrovirus expression screening
- Principal Investigator
  
  FUJIWARA Shinichiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
Novel mechanisms of drug resistance in leukemia and the new molecular target therapeutic strategies.Principal Investigator
- Principal Investigator
  
  OHMINE Ken
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL SCHOOL
Analysis of the mechanisms of drug resistance in leukemia cells
- Principal Investigator
  
  NAGAI Tadashi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
Investigations of mechanisms of drug-resistance in leukemia cells
- Principal Investigator
  
  NAGAI Tadashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical School
転写調節によるエリスロポエチン遺伝子発現制御機構Principal Investigator
- Principal Investigator
  
  大嶺謙
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] A leukemic double-hit follicular lymphoma associated with a complex variant translocation, t(8;14;18)(q24;q32;q21), involving BCL2, MYC, and IGH2018
- Author(s)
  Minakata Daisuke、Sato Kazuya、Ashizawa Masahiro、Hatano Kaoru、Oh Iekuni、Fujiwara Shin-ichiro、Ohmine Ken、Kawata Hirotoshi、Muroi Kazuo、Miura Ikuo、Kanda Yoshinobu、et al
- Journal Title
  
  Cancer Genetics
  
  Volume: 220 Pages: 44-48
- DOI
  10.1016/j.cancergen.2017.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] キメラ抗原受容体T細胞療法2018
- Author(s)
  永山　隆史、大嶺　謙
- Journal Title
  
  最新医学
  
  Volume: 73 Pages: 83-91
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Comprehensive Analysis of the Activation and Proliferation Kinetics and Effector Functions of Human Lymphocytes, and Antigen Presentation Capacity of Antigen-Presenting Cells in Xenogeneic Graft-Versus-Host Disease2018
- Author(s)
  Kawasaki Yasufumi、Sato Kazuya、Hayakawa Hiroko、Takayama Norihito、Nakano Hirofumi、Ito Ryoji、Mashima Kiyomi、Oh Iekuni、Minakata Daisuke、Yamasaki Ryoko、Morita Kaoru、Ashizawa Masahiro、Yamamoto Chihiro、Hatano Kaoru、Fujiwara Shin-ichiro、Ohmine Ken、Muroi Kazuo、Kanda Yoshinobu
- Journal Title
  
  Biology of Blood and Marrow Transplantation
  
  Volume: 印刷中 Issue: 8 Pages: 1563-1574
- DOI
  10.1016/j.bbmt.2018.04.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430168, KAKENHI-PROJECT-18K08369, KAKENHI-PROJECT-17H03571, KAKENHI-PROJECT-16K07103
[Journal Article] Clinical outcomes of myeloid/lymphoid neoplasms with fibroblast growth factor receptor-1 (FGFR1) rearrangement2018
- Author(s)
  Umino Kento、Fujiwara Shin-ichiro、Ikeda Takashi、Toda Yumiko、Ito Shoko、Mashima Kiyomi、Minakata Daisuke、Nakano Hirofumi、Yamasaki Ryoko、Kawasaki Yasufumi、Sugimoto Miyuki、Yamamoto Chihiro、Ashizawa Masahiro、Hatano Kaoru、Sato Kazuya、Oh Iekuni、Ohmine Ken、Muroi Kazuo、Kanda Yoshinobu
- Journal Title
  
  Hematology
  
  Volume: 印刷中 Issue: 8 Pages: 470-477
- DOI
  10.1080/10245332.2018.1446279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Prognostic value of the soluble interleukin-2 receptor level after patients with follicular lymphoma achieve a response to R-CHOP.2017
- Author(s)
  Umino K, Fujiwara SI, Ikeda T, Toda Y, Ito S, Mashima K, Minakata D, Nakano H, Yamasaki R, Kawasaki Y, Sugimoto M, Yamamoto C, Ashizawa M, Hatano K, Sato K, Oh I, Ohmine K, Muroi K, Kanda Y.
- Journal Title
  
  Hematology.
  
  Volume: 17 Issue: 9 Pages: 1-6
- DOI
  10.1080/10245332.2017.1312204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19556, KAKENHI-PROJECT-26430168
[Journal Article] B細胞性造血器腫瘍（白血病・悪性リンパ腫）に対するCD19特異的CAR-T療法の臨床開発2017
- Author(s)
  大嶺　謙、皆方大祐
- Journal Title
  
  血液フロンティア
  
  Volume: 27 Pages: 961-968
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Development of acute myeloid leukemia in patients with untreated chronic lymphocytic leukemia.2017
- Author(s)
  Ito S, Fujiwara SI, Mashima K, Umino K, Minakata D, Nakano H, Yamasaki R, Kawasaki Y, Sugimoto M, Ashizawa M, Yamamoto C, Hatano K, Okazuka K, Sato K, Oh I, Ohmine K, Suzuki T, Muroi K, Kanda Y.
- Journal Title
  
  Ann Hematol.
  
  Volume: 96 Issue: 5 Pages: 719-724
- DOI
  10.1007/s00277-017-2933-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19556, KAKENHI-PROJECT-26430168
[Journal Article] Relationship between white blood cell count elevation and clinical response after G-CSF priming chemotherapy for acute myeloid leukemia2017
- Author(s)
  Minakata Daisuke、Fujiwara Shin-ichiro、Ikeda Takashi、Toda Yumiko、Ito Shoko、Mashima Kiyomi、Umino Kento、Nakano Hirofumi、Yamasaki Ryoko、Morita Kaoru、Kawasaki Yasufumi、Sugimoto Miyuki、Yamamoto Chihiro、Ashizawa Masahiro、Hatano Kaoru、Sato Kazuya、Oh Iekuni、Ohmine Ken、Muroi Kazuo、Kanda Yoshinobu
- Journal Title
  
  International Journal of Hematology
  
  Volume: 106 Issue: 3 Pages: 411-417
- DOI
  10.1007/s12185-017-2251-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Nilotinib vs. imatinib in Japanese patients with newly diagnosed chronic myeloid leukemia in chronic phase: long-term follow-up of the Japanese subgroup of the randomized ENESTnd trial2017
- Author(s)
  Nakamae H, Fukuda T, Nakaseko C, Kanda Y, Ohmine K, Ono T, Matsumura I,Matsuda A, Aoki M, Ito K, Shibayama H.
- Journal Title
  
  Int J Hematol.
  
  Volume: 107 Issue: 3 Pages: 327-336
- DOI
  10.1007/s12185-017-2353-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09461, KAKENHI-PROJECT-26430168, KAKENHI-PROJECT-18K08375
[Journal Article] CD25 as an adverse prognostic factor in elderly patients with acute myeloid leukemia.2017
- Author(s)
  Fujiwara SI, Muroi K, Yamamoto C, Hatano K, Okazuka K, Sato K, Oh I, Ohmine K, Suzuki T, Ozawa K.
- Journal Title
  
  Hematology
  
  Volume: 18 Issue: 6 Pages: 1-7
- DOI
  10.1080/10245332.2016.1276240
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19556, KAKENHI-PROJECT-26430168
[Journal Article] ALLに対するCD19を標的としたCAR-T療法2017
- Author(s)
  皆方大祐、大嶺　謙
- Journal Title
  
  血液内科
  
  Volume: 75 Pages: 330-337
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] キメラ抗原受容体発現Tリンパ球(CAR-T)を用いた養子免疫遺伝子療法2017
- Author(s)
  海野健斗、大嶺　謙
- Journal Title
  
  血液疾患最新の治療2017-2019
  
  Volume: - Pages: 51-58
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] High-Dose Methotrexate and Cytarabine-Based Multi-Agent Chemotherapy (Modified Bonn Protocol) for Systemic Lymphoma with CNS Involvement.2017
- Author(s)
  Umino K, Fujiwara SI, Sato K, Minakata D, Nakano H, Yamasaki R, Kawasaki Y, Sugimoto M, Yamamoto C, Hatano K, Okazuka K, Oh I, Ohmine K, Suzuki T, Muroi K, Kanda Y.
- Journal Title
  
  Acta Haematol.
  
  Volume: 137 Issue: 2 Pages: 93-99
- DOI
  10.1159/000454890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19556, KAKENHI-PROJECT-26430168
[Journal Article] Successful treatment of follicular lymphoma with second-generation tyrosine kinase inhibitors administered for coexisting chronic myeloid leukemia2017
- Author(s)
  Fujiwara Shin-ichiro、Shirato Yuya、Minakata Daisuke、Nakano Hirofumi、Morita Kaoru、Yamasaki Ryoko、Kawasaki Yasufumi、Sugimoto Miyuki、Ashizawa Masahiro、Yamamoto Chihiro、Hatano Kaoru、Sato Kazuya、Oh Iekuni、Ohmine Ken、Muroi Kazuo、Kanda Yoshinobu、et al
- Journal Title
  
  International Journal of Hematology
  
  Volume: 107 Issue: 6 Pages: 712-715
- DOI
  10.1007/s12185-017-2378-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Retrospective evaluation of the MEAM regimen as a conditioning regimen before autologous peripheral blood stem cell transplantation for lymphoma in two centers with different dosing schedules of melphalan.2016
- Author(s)
  Sugimoto M, Ito S, Mashima K, Umino K, Minakata D, Nakano H, Yamasaki R, Kawasaki Y, Ashizawa M, Yamamoto C, Fujiwara SI, Okazuka K, Hatano K, Sato K, Oh I, Ohmine K, Suzuki T, Muroi K, Kako S, Kanda Y.
- Journal Title
  
  Ann Hematol.
  
  Volume: 95 Issue: 9 Pages: 1513-9
- DOI
  10.1007/s00277-016-2740-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-26430168
[Journal Article] リンパ腫に対するキメラ抗原受容体(CAR)を用いた遺伝子改変T細胞療法2016
- Author(s)
  大嶺　謙
- Journal Title
  
  内科
  
  Volume: 117 Pages: 1369-1373
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] CAR-T療法～難治性骨髄腫に対するキメラ抗原受容体発現Tリンパ球を用いた養子免疫遺伝子療法～2016
- Author(s)
  大嶺　謙
- Journal Title
  
  多発性骨髄腫 Updating
  
  Volume: 9 Pages: 124-135
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Dose-reduced combination of mitoxantrone, etoposide, and cytarabine (miniMEC) for relapsed and refractory acute leukemia.2016
- Author(s)
  Yamamoto, C., Ito, S., Mashima, K., Umino, K., Minakata, D., Yamasaki, R., Kawasaki, Y., Sugimoto, M., Nakano, H., Ashizawa, M., Okazuka, K., Hatano, K., Sato, K., Oh, I., Fujiwara S, Ohmine, K., Suzuki, T., Muroi, K., Kanda, Y.
- Journal Title
  
  Leuk. Lymphoma.
  
  Volume: 57 Issue: 11 Pages: 2541-2547
- DOI
  10.3109/10428194.2016.1153087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] The prognostic significance of rapid peripheral blood blast clearance during the initial course of induction chemotherapy in young patients with de novo acute myeloid leukemia.2016
- Author(s)
  Nakano H, Fujiwara SI, Ito S, Mashima K, Umino K, Minakata D, Yamasaki R, Kawasaki Y, Sugimoto M, Ashizawa M, Yamamoto C, Hatano K, Okazuka K, Sato K, Oh I, Ohmine K, Suzuki T, Muroi K, Kanda Y
- Journal Title
  
  Hematol Oncol.
  
  Volume: in press Issue: 3 Pages: 1-1
- DOI
  10.1002/hon.2277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-26430168, KAKENHI-PROJECT-15K19556
[Journal Article] A low-dose cytarabine, aclarubicin and granulocyte colony-stimulating factor priming regimen versus a daunorubicin plus cytarabine regimen as induction therapy for older patients with acute myeloid leukemia: A propensity score analysis.2016
- Author(s)
  Minakata D, Fujiwara SI, Ito S, Mashima K, Umino K, Nakano H, Kawasaki Y, Sugimoto M, Yamasaki R, Yamamoto C, Ashizawa M, Hatano K, Okazuka K, Sato K, Oh I, Ohmine K, Suzuki T, Muroi K, Kanda Y
- Journal Title
  
  Leuk Res.
  
  Volume: 42 Pages: 82-87
- DOI
  10.1016/j.leukres.2015.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-26430168, KAKENHI-PROJECT-15K19556
[Journal Article] ALLに対するCAR療法2016
- Author(s)
  海野健斗、大嶺　謙
- Journal Title
  
  最新医学
  
  Volume: 71 Pages: 50-56
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Efficacy of combination therapy with anti-thymocyte globulin and cyclosporine A as a first-line treatment in adult patients with aplastic anemia: a comparison of rabbit and horse formulations.2016
- Author(s)
  Suzuki T, Kobayashi H, Kawasaki Y, Okazuka K, Hatano K, Fujiwara S, Oh I, Ohmine K, Kanda Y.
- Journal Title
  
  Int J Hematol
  
  Volume: 104 Issue: 4 Pages: 446-53
- DOI
  10.1007/s12185-016-2046-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-26430168
[Journal Article] Dose-reduced combination of mitoxantrone, etoposide, and cytarabine (miniMEC) for relapsed and refractory acute leukemia.2016
- Author(s)
  Yamamoto C, Ito S, Mashima K, Umino K, Minakata D, Yamasaki R, Kawasaki Y, Sugimoto M, Nakano H, Ashizawa M, Okazuka K, Hatano K, Sato K, Oh I, Fujiwara SI, Ohmine K, Suzuki T, Muroi K, Kanda Y.
- Journal Title
  
  Leuk Lymphoma.
  
  Volume: 25 Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] CD19特異的CAR発現T細胞を用いた造血器腫瘍の治療2015
- Author(s)
  海野健斗、大嶺　謙
- Journal Title
  
  血液内科
  
  Volume: 71 Pages: 493-499
- NAID
  40020643080
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] パノビノスタット2015
- Author(s)
  大嶺謙
- Journal Title
  
  最新医学別冊診断と治療のABC 血液領域の分子標的治療薬
  
  Volume: 102 Pages: 187-196
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] CD19特異的キメラ抗原受容体を発現させたTリンパ球を用いる癌遺伝子治療2015
- Author(s)
  岡塚貴世志、大嶺　謙
- Journal Title
  
  血液フロンティア
  
  Volume: 25 Pages: 71-77
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] 難治性B細胞性造血器腫瘍に対するCD19特異的キメラ抗原受容体(CAR)遺伝子治療は今後の細胞免疫療法の行方を占うか？2015
- Author(s)
  大嶺　謙
- Journal Title
  
  内科
  
  Volume: 116 Pages: 1-1
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] Distribution of serum erythropoietin levels in Japanese patients with myelodysplastic syndromes.2015
- Author(s)
  Suzuki T, Oh I, Ohmine K, Meguro A, Mori M, Fujiwara S, Yamamoto C, Nagai T, Ozawa K.
- Journal Title
  
  Int J Hematol.
  
  Volume: 101 Issue: 1 Pages: 32-36
- DOI
  10.1007/s12185-014-1699-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-15K09489, KAKENHI-PROJECT-25461459
[Journal Article] The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies2015
- Author(s)
  Tsukahara, T., Iwase, N., Kawakami, K., Iwasaki, M., Yamamoto, C., Ohmine, K., Uchibori, R., Teruya, T., Ido, H., Saga, Y., Urabe, M., Mizukami, H., Kume, A., Nakamura, M., Brentjens, R., and Ozawa, K.
- Journal Title
  
  Gene Therapy
  
  Volume: 22 Issue: 2 Pages: 209-215
- DOI
  10.1038/gt.2014.104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23241063, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-26430168
[Journal Article] Central retinal vein occlusion caused by hyperviscosity syndrome in a young patient with Sjögren's syndrome and MALT lymphoma.2015
- Author(s)
  Yoshida A, Watanabe M, Ohmine K, Kawashima H.
- Journal Title
  
  Int Ophthalmol.
  
  Volume: 35 Issue: 3 Pages: 429-32
- DOI
  10.1007/s10792-015-0056-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-26430168
[Journal Article] Effect of Intra-Medullar and Intra-Venous Infusions of Mesenchymal Stem Cells on Cell Engraftment by In-Vivo Cell Tracking and Osteoinductivity in Rabbit Long Bones: A Pilot Study.2014
- Author(s)
  Ishihara A, Ohmine K, Weisbrode SE, Bertone AL.
- Journal Title
  
  Orthop Muscular Syst.
  
  Volume: 3 Issue: 03 Pages: 1-5
- DOI
  10.4172/2161-0533.1000172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-26430168
[Journal Article] L-21 is not necessary for anti-lymphoma effects of T cells expressing second-generation CD19-specific chimeric antigen receptors in a xenograft mouse model.2014
- Author(s)
  Yamamoto C , Tsukahara T, Ohmine K, Teruya T, Ido H, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Journal Title
  
  Jichi Medical University Journal
  
  Volume: 36 Pages: 23-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25430155
[Journal Article] Intrathecal administration of high-titer cytomegalovirus immunoglobulin for cytomegalovirus meningitis.2014
- Author(s)
  Fujiwara S, Muroi K, Tatara R, Ohmine K, Matsuyama T, Mori M, Nagai T, Ozawa K.
- Journal Title
  
  Case Rep Hematol.
  
  Volume: 2014 Pages: 1-3
- DOI
  10.1155/2014/272458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-26430168
[Journal Article] Cancer gene therapy using mesenchymal stem cells.2014
- Author(s)
  Uchibori R, Tsukahara T, Ohmine K, Ozawa K.
- Journal Title
  
  Int J Hematol.
  
  Volume: 99 Issue: 4 Pages: 377-82
- DOI
  10.1007/s12185-014-1537-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25430155, KAKENHI-PROJECT-26430168
[Journal Article] Mechanisms of resistance to azacitidine in human leukemia cell lines.2014
- Author(s)
  Sripayap P, Nagai T, Uesawa M, Kobayashi H, Tsukahara T, Ohmine K, Muroi K, Ozawa K.
- Journal Title
  
  Exp Hematol.
  
  Volume: 42 Issue: 4 Pages: 294-306
- DOI
  10.1016/j.exphem.2013.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-25461435, KAKENHI-PROJECT-26430168
[Journal Article] 身近な話題・世界の話題　急性リンパ球性白血病に対するCD19特異的キメラ抗原受容体を用いた遺伝子治療(解説)2014
- Author(s)
  大嶺謙
- Journal Title
  
  血液フロンティア
  
  Volume: 24 Pages: 608-614
- Data Source
  KAKENHI-PROJECT-26430168
[Journal Article] CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models2013
- Author(s)
  Tsukahara T, Ohmine K, Yamamoto C, Uchibori R, Ido H, Teruya T, Urabe M, Mizukami H, Kume A, Nakamura M, Mineno J, Takesako K, Riviere I, Sadelain M, Brentjens R, Ozawa K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 438 Issue: 1 Pages: 84-89
- DOI
  10.1016/j.bbrc.2013.07.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591548, KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-24700995, KAKENHI-PROJECT-25430155
[Journal Article] Rituximab-induced interstitial pneumonia dueto CD8-positive T-cell infiltration2012
- Author(s)
  Sato, K., Nagai, T., Izumi, T., Ohmine, K.,Ozaki, K., Muroi, K., and Ozawa, K.
- Journal Title
  
  ActaHaematologica
  
  Volume: 128 Issue: 2 Pages: 107-109
- DOI
  10.1159/000338259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591048
[Journal Article] Vincristine potentiates the anti-proliferativeeffect of an aurora kinase inhibitor, VE-465,in myeloid leukemia cells.2011
- Author(s)
  Yoshida, K., Nagai, T., Ohmine, K., Uesawa,M., Sripayap, P., Ishida, Y., and Ozawa, K.
- Journal Title
  
  Biochem.Pharmcol.
  
  Volume: 82 Pages: 1884-1890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591048
[Journal Article] Incidental carcinomasdetected by PET/CT scans in patients withmalignant lymphoma.2010
- Author(s)
  Sato, K., Ozaki, K., Matsuyama, T., Ohmine,K., Suzuki, T., Mori, M., Nagai, T., Muroi,K., and Ozawa, K.:
- Journal Title
  
  Int J Hematol
  
  Volume: 92 Issue: 4 Pages: 647-650
- DOI
  10.1007/s12185-010-0702-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591048
[Journal Article] Combination of tipifarnib and rapamycinsynergistically inhibits the growth ofleukemia cells and overcomes resistance totipifarnib via alteration of cellular signalingpathways.2010
- Author(s)
  Nagai, T., Ohmine, K., Fujiwara, S., Uesawa,M., Sakurai, C., and Ozawa, K.
- Journal Title
  
  Leukemia Res.
  
  Volume: 34 Pages: 1057-1063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591048
[Presentation] キメラ抗原受容体導入T細胞を用いた B細胞性造血器腫瘍に対する免疫細胞療法の臨床開発2018
- Author(s)
  大嶺　謙
- Organizer
  第17回日本再生医療学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CAR-T療法の実際と問題点2018
- Author(s)
  大嶺　謙
- Organizer
  バイオロジクスフォーラム第15回学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Clinical development of CAR-T Therapy for Multiple Myeloma2017
- Author(s)
  Ken Ohmine, Ryosuke Uchibori, Keiya Ozawa
- Organizer
  第73回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Clinical development of adoptive immunotherapy with Chimeric Antigen Receptor-modified T-cells in patients with Multiple Myeloma2017
- Author(s)
  Ken Ohmine
- Organizer
  1st Annual AMN Summit
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Clinical development of CD19-CAR therapy in patients with B-cell malignancy2016
- Author(s)
  大嶺　謙
- Organizer
  第22回日本遺伝子細胞治療学会学術集会
- Place of Presentation
  虎ノ門ヒルズフォーラム(東京都港区)
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Phase Ⅰ/Ⅱ trial of CD19 Chimeric Antigen Receptor T-cell therapy in patients with relapsed and refractory Non-Hodgkin lymphoma.2016
- Author(s)
  Ohmine, K.
- Organizer
  第7回JSH国際シンポジウム
- Place of Presentation
  淡路夢舞台国際会議場(兵庫県淡路市)
- Year and Date
  2016-05-13
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] 再発・難治性非ホジキンリンパ腫に対するCD19特異的キメラ抗原受容体(CAR)療法2016
- Author(s)
  大嶺　謙
- Organizer
  第20回日本がん免疫学会総会
- Place of Presentation
  大阪国際交流センター(大阪府大阪市)
- Year and Date
  2016-07-27
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Clinical development of adoptive immunotherapy with CD19-specific chimeric antigen receptor-modified T-cells in patients with B-cell malignancy2016
- Author(s)
  Ohmine, K.
- Organizer
  The 29th Annual and International Meeting of Japanese Association for Animal Cell Technology
- Place of Presentation
  神戸国際会議場(兵庫県神戸市)
- Year and Date
  2016-11-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Factor XIII deficiency deteriorates bleeding symptom in a patient with anti-factor XI inhibitor.2016
- Author(s)
  大嶺謙、窓岩清治、畑野かおる、尾崎司、惣宇利正善、一瀬白帝、大森司、坂田洋一、村田満、神田善伸
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] 産学協同によるCAR-T療法の開発2016
- Author(s)
  大嶺　謙
- Organizer
  第38回日本造血細胞移植学会総会
- Place of Presentation
  名古屋
- Year and Date
  2016-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CD19特異的キメラ抗原受容体(CAR)療法の臨床試験.2016
- Author(s)
  大嶺　謙
- Organizer
  第64回日本輸血・細胞治療学会総会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2016-04-28
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CAR-Tを用いたがん免疫遺伝子細胞療法の展開と併用療法への視点2015
- Author(s)
  大嶺　謙
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  松山
- Year and Date
  2015-06-12
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CD19 特異的CAR発現Tリンパ球を用いた悪性リンパ腫に対する遺伝子治療2015
- Author(s)
  大嶺　謙
- Organizer
  第55回日本リンパ網内系学会総会
- Place of Presentation
  岡山
- Year and Date
  2015-07-10
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CD19特異的キメラ抗原受容体(CAR)発現T細胞を用いた養子免疫療法の臨床開発2015
- Author(s)
  大嶺　謙
- Organizer
  第7回血液疾患免疫療法研究会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25430155
[Presentation] Adoptive immunotherapy with CD19-specific chimeric antigen receptor-modified T Cells2015
- Author(s)
  大嶺　謙
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-09
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CD19特異的キメラ抗原受容体(CAR)発現T細胞を用いた養子免疫療法の臨床開発2015
- Author(s)
  大嶺　謙
- Organizer
  第7回血液疾患免疫療法研究会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] The NFAT response elements in the IL-2 gene promoter permit visualization and quantification of activation status in CAR-expressing PBMCs.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Activation signals from CAR permit NFAT-controlled inducible expression of transgenes in PBMCs.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tol2 transposon-based gene transfer of CD19-specific chimeric antigen receptors into human T-cells.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Teruya T, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R, Kawakami K and Ozawa K.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Activation signals from chimeric antigen receptors permit NFAT-controlled inducible expression of transgene in PBMCs.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Analysis of function and response specificity of a switch promoter driven by activation signals from a CD19-targeted chimeric antigen receptor.2014
- Author(s)
  Uchibori R, Takeshi T, Tsukahara T, Ohmine K, Riviere I, Brentjens RJ, Sadelain M, Mineno J, Takesako K, Ozawa K.
- Organizer
  The 5th Meeting of Asian Cellular Therapy Organization.
- Place of Presentation
  大阪
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] 細胞療法の現状と将来キメラ抗原受容体発現Tリンパ球を用いたB細胞性腫瘍に対する遺伝子治療2014
- Author(s)
  大嶺謙
- Organizer
  第62回日本輸血・細胞治療学会総会
- Place of Presentation
  奈良
- Year and Date
  2014-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] フィラデルフィア染色体陽性急性白血病に対するPSL併用Dasatinib療法の効果と安全性に関する報告2014
- Author(s)
  翁家国, 多々良礼音, 藤原慎一郎, 大嶺謙, 鈴木隆浩, 永井正, 室井一男, 小澤敬也
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] B細胞リンパ腫に合併した腫瘍随伴性天疱瘡と考えた1例2014
- Author(s)
  坂口優, 宮本有希子, 佐藤篤子, 藤田有理香, 小宮根真弓, 村田哲, 大槻マミ太郎, 佐藤一也, 大嶺謙, 小澤敬也
- Organizer
  第113回日本皮膚科学会総会
- Place of Presentation
  京都
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tol2 transposon-mediated gene transfer of CD19-CAR to primary human T-cells for the treatment of B-cell malignancies.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Takeshi T, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R J, Kawakami K, Ozawa K.
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-25430155
[Presentation] フィラデルフィア染色体陽性急性白血病に対するPSL併用Dasatinib療法の効果と安全性に関する報告2014
- Author(s)
  翁家国, 多々良礼音, 藤原慎一郎, 大嶺謙, 鈴木隆浩, 永井正, 室井一男, 小澤敬也
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Generation of T-cells expressing a CD19-specific CAR by the Tol2 transposon system.2014
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] 細胞療法の現状と将来キメラ抗原受容体発現Tリンパ球を用いたB細胞性腫瘍に対する遺伝子治療2014
- Author(s)
  大嶺　謙
- Organizer
  第62回日本輸血・細胞治療学会総会
- Place of Presentation
  奈良
- Year and Date
  2014-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Generation of T-cells expressing a CD19-specific CAR by the Tol2 transposon system.2014
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tol2 transposon-based gene transfer of CD19-specific chimeric antigen receptors into human T-cells.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Teruya T, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R, Kawakami K and Ozawa K.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-25430155
[Presentation] CD19特異的キメラ抗原受容体発現Tリンパ球を用いた難治性B細胞性悪性リンパ腫に対する遺伝子治療2014
- Author(s)
  大嶺　謙
- Organizer
  IMSUT-CGCTキックオフ・シンポジウム2014
- Place of Presentation
  東京
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Development of switch promoters that is activated to induce exogenous gene expression upon the recognition of CD19 by chimeric antigen receptors.2014
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  17th Annual Meeting of the American Society of Gene & Cell Therapy.
- Place of Presentation
  Washington, D.C.
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tol2 transposon-mediated gene transfer of CD19-CAR to primary human T-cells for the treatment of B-cell malignancies.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Takeshi T, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R J, Kawakami K, Ozawa K.
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] キメラ抗原受容体からの抗原刺激特異的な遺伝子発現誘導系の開発.2014
- Author(s)
  内堀亮介, 二宮空暢, 照屋武志, 塚原智典, 大嶺謙, 峰野純一, 竹迫一任, 小澤敬也.
- Organizer
  第6回血液疾患免疫療法研究会
- Place of Presentation
  京都
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] B細胞リンパ腫に合併した腫瘍随伴性天疱瘡と考えた1例2014
- Author(s)
  坂口優, 宮本有希子, 佐藤篤子, 藤田有理香, 小宮根真弓, 村田哲, 大槻マミ太郎, 佐藤一也, 大嶺謙, 小澤敬也
- Organizer
  第113回日本皮膚科学会総会
- Place of Presentation
  京都
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Tol2 transposon-mediated gene transfer of CD19-CAR to primary human T-cells for the treatment of B-cell malignancies.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Takeshi T, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R J, Kawakami K, Ozawa K.
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  東京
- Year and Date
  2014-08-08
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] CD19特異的キメラ抗原受容体発現Tリンパ球を用いた難治性B細胞性悪性リンパ腫に対する遺伝子治療2014
- Author(s)
  大嶺謙
- Organizer
  IMSUT-CGCTキックオフ・シンポジウム2014
- Place of Presentation
  東京
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Generation of T-cells expressing a CD19-specific CAR by the Tol2 transposon system.2014
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-25430155
[Presentation] Tol2 transposon-based gene transfer of CD19-specific chimeric antigen receptors into human T-cells.2014
- Author(s)
  Tsukahara T, Iwase N, Yamamoto C, Ohmine K, Uchibori R, Teruya T, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Brentjens R, Kawakami K and Ozawa K.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-02
- Data Source
  KAKENHI-PROJECT-26430168
[Presentation] Crucial role of RCAN1 in leukemia progression.2010
- Author(s)
  Shin-ichiro Fujiwara, Tadashi Nagai, Satoru Kikuchi, Mitsuyo Uesawa, Chihiro Sakurai, Ken Ohmine, Jiro Kikuchi, Yusuke Furukawa, Keiya Ozawa.
- Organizer
  69^<th> Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Osaka
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790921
[Presentation] Ectopic Expression and Role of RCAN1 in Myeloid Leukemia Cells.2009
- Author(s)
  Shin-ichiro Fujiwara, Tadashi Nagai, Satoru Kikuchi, Mitsuyo Uesawa, Chihiro Sakurai, Ken Ohmine, Jiro Kikuchi, Yusuke Furukawa, Keiya Ozawa.
- Organizer
  American Society of Hematology Annual Meeting
- Place of Presentation
  New Orleans.
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-21790921
[Presentation] Development of switch promoters driven by activation signals from the chimeric antigen receptors.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ohmine K, Urabe M, Mizukami H, Kume A, Mineno J, Ozawa K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tumor targeting and anti-tumor activity mediated by T-lymphocytes with an anti-CD19 CAR in human B-cell lymphoma models.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  第18日本遺伝子治療学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-25430155
[Presentation] Tumor targeting using T-lymphocytes with an anti-CD19 chimeric antigen receptor for B cell lymphoma.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25430155
[Presentation] Anti-tumor activity of CD19-specific chimeric antigen receptor-modified T-cells for B cell lymphoma.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tumor targeting using T-lymphocytes with an anti-CD19 chimeric antigen receptor for B cell lymphoma.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] DEVELOPMENT OF SIN RETROVIRAL VECTORS EQUIPPED WITH SWITCH PROMOTERS DRIVEN BY ACTIVATION SIGNALS FROM THE CHIMERIC ANTIGEN RECEPTORS.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Development of switch promoters that would respond to activation signals from the chimeric antigen receptors.
- Author(s)
  Uchibori R, Ninomiya S, Tsukahara T, Ido H, Teruya T, Ohmine K, Urabe M, Mizukami H, Kume A, Riviere I, Sadelain M, Brentjens RJ, Mineno J, Ozawa K.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Tumor targeting and anti-tumor activity mediated by T-lymphocytes with an anti-CD19 CAR in human B-cell lymphoma models.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Riviere I, Sadelain M, Brentjens R, Ozawa K.
- Organizer
  第18回日本遺伝子治療学会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-24390247
[Presentation] Anti-tumor activity of CD19-specific chimeric antigen receptor-modified T-cells for B cell lymphoma.
- Author(s)
  Tsukahara T, Ohmine K, Uchibori R, Ido H, Urabe M, Mizukami H, Kume A, Nakamura M, Ozawa K.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25430155

1. NAGAI Tadashi (40237483)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
2. TSUKAHARA Tomonori (10362120)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
3. FUJIWARA Shinichiro (20438667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. OZAWA keiya (30137707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
5. UCHIBORI Ryousuke (20458285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
6. MORISHITA Kazuhiro (80260321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KIKUCHI Satoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. UESAWA Mitsuyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. YAMAMOTO Chihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 室井一男

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 鈴木隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. 松村到

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 久米晃啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 川上浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHMINE Ken 大嶺 謙

大嶺 謙 オオミネ ケン

OHMINA Ken 大嶺 謙

Research Projects

Research Products

Co-Researchers

Safety and persistence of genetically modified T-cells in patients with non-Hodgkin lymphomaPrincipal Investigator

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Development of immunogene therapy using T-cells expressing a chimeric antigen receptor for adult T-cell leukemia

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Development of gene therapy for refractory non-Hodgkin lymphoma using T-cells expressing a chimeric antigen receptor

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Clarification of RCAN1-mediated deregulation of cellular functionsin leukemia cells

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Identification of oncogenes in T cell lymphoma by retrovirus expression screening

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Novel mechanisms of drug resistance in leukemia and the new molecular target therapeutic strategies.Principal Investigator

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Analysis of the mechanisms of drug resistance in leukemia cells

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Investigations of mechanisms of drug-resistance in leukemia cells

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転写調節によるエリスロポエチン遺伝子発現制御機構Principal Investigator

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[Journal Article] A leukemic double-hit follicular lymphoma associated with a complex variant translocation, t(8;14;18)(q24;q32;q21), involving BCL2, MYC, and IGH2018

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[Journal Article] キメラ抗原受容体T細胞療法2018

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[Journal Article] Comprehensive Analysis of the Activation and Proliferation Kinetics and Effector Functions of Human Lymphocytes, and Antigen Presentation Capacity of Antigen-Presenting Cells in Xenogeneic Graft-Versus-Host Disease2018

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[Journal Article] Clinical outcomes of myeloid/lymphoid neoplasms with fibroblast growth factor receptor-1 (FGFR1) rearrangement2018

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[Journal Article] Prognostic value of the soluble interleukin-2 receptor level after patients with follicular lymphoma achieve a response to R-CHOP.2017

OHMINE Ken 大嶺謙

大嶺謙オオミネケン

OHMINA Ken 大嶺謙