RI Syouten 李勝天

Researcher Number	90325093
Affiliation (based on the past Project Information) *help	2004: 株式会社三菱化学生命科学研究所, 研究部門, 特別研究員 2003: Okayama University Graduate Schools, Graduate School of Medicine and Dentistry, Assistant Professor 2001 – 2003: Okayama University, Graduate School of Medicine and Dentistry, Assistant, 大学院・医歯学総合研究科, 助手 2000: Medical School, OKAYAMA UNIVERSITY, Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator General physiology Except Principal Investigator Ophthalmology / General physiology / Environmental physiology (including Physical medicine and Nutritional physiology) / Neuroscience in general / Cerebral neurosurgery / 神経・脳内生理学 / Biological Sciences
Keywords	Principal Investigator 代謝型グルタミン酸受容体 / 長期抑圧現象 / リアノジン受容体 / IP3受容体 / カルシウムストア / 長期抑圧現象(LTD) / 代謝型グルタミン酸受容体(mGluR) / カルシニューリン Except Principal Investigator FK506 / Ca^<2+> … More / Neuronal cell death / Calcineurin / 神経細胞死 / カルシニューリン / 長期増強 / Elongation Factor 2 / Protein therapy / Glutamate / Calpastatin / Calpain / カルパイン / グルタミン酸 / 膀胱肥大 / シクロスポリン / FK506結合蛋白質 / 免疫抑制剤 / カルシウムチャネル / PKI / Aキナーゼ / TAT / In vivo Protein Transduction / 蛋白質セラピー / optic nerve / knockout mice / hyaluronan / proteoglycan / Hapln2 / Bral1 / ノックアウトマウス / ヒアルロン酸 / 視神経 / リンクプロテイン / プロテオグリカン / ランビエ絞輪 / Kainate / タンパク質セラピー法 / カイニン酸 / カルパスタチン / Translation / calmodulin-dependent protein kinase / PVN / SON / oxytocin / vasopressin / Ca+2カルモデュリン依存性キナーゼIII / Ca2+ / 翻訳制御 / カルモデュリンキナーゼIII / 視索上核 / 室傍核 / オキシトシン / バソプレシン / Nitric oxide / Late phase long-term potentiation / Long term potentiation / 一酸化窒素 / 超長期増強 / Apoptosis / アポトーシス / カルバスタチン / Invivo Protein Transduction / 蛋白質セラピー法 / Urinary bladder hypertrophy / Cyclosporin / FKBP / Immunosuppressant / Ca channel / NMDA / シクロフィリン / ホスファターゼ Less

プレシナプスのカルシニューリンによるシナプス可塑性の制御機構の解明Principal Investigator
- Principal Investigator
  
  李勝天
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Mitsubishi Kagaku Institute of Life Sciences
  Okayama University
Imaging and functional regulation of microenvironment in subcellular organelle
- Principal Investigator
  
  MATSUI Hideki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  OKAYAMA UNIVERSITY
Molecular biological and electrophyrsiological studies of extranodal matrices on the saltatory conduction of the optic nerve
- Principal Investigator
  
  OOHASHI Toshitaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  OKAYAMA UNIVERSITY
Translational regulation of vasopressin synthesis
- Principal Investigator
  
  MORIWAKI Akiyoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  CHUGOKUGAKUEN UNIVERSITY
  Okayama University
蛋白質セラピー法による興奮性ニューロン死の防止と新しい脳保護薬創出の試み
- Principal Investigator
  
  MATSUI Hideki
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Okayama University
Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration
- Principal Investigator
  
  MATSUI Hideki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  OKAYAMA UNIVERSITY
THE MECHANlSM OF LAIE-PHASE LTP INDUCTION
- Principal Investigator
  
  MORIWAKI Akiyoshi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  OKAYAMA UNIVERSITY
The mechanism of Ca2+ ion inflow regulated by KF506 binding proteins (FKBP) and Calcineurin.
- Principal Investigator
  
  MATSUI Hideki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  神経・脳内生理学
- Research Institution
  OKAYAMA UNIVERSITY

All 2004 2003 2002 Other

All Journal Article

[Journal Article] Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration2004
- Author(s)
  Wu HY, Tomizawa K, Oda Y, Wei FY, Lu YF, Matsushita M, Li ST, Moriwaki A, Matsui H
- Journal Title
  
  J Biol Chem 279,6
  
  Pages: 4929-4940
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] A new cell-permeable peptide allows successful allogeneic islet transplantation in mice.2004
- Author(s)
  Noguchi H, Matsushita M, Okitsu T, Moriwaki A, Tomizawa K, Kang S, Li ST, Kobayashi N, Matsumoto S, Tanaka K, Tanaka N, Matsui H.
- Journal Title
  
  Nat Med. Mar;10(3)
  
  Pages: 305-309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] HIV-1 tat inhibits long-term potentiation and attenuates spatial learning.2004
- Author(s)
  Li, S-T., Matsushita, M., Moriwaki, A., Tomizawa, K., Matsui, H.
- Journal Title
  
  Ann.Neurol. 55
  
  Pages: 362-371
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390064
[Journal Article] HIV-1 Tat Inhibits Long-Term Potentiation and Attenuates Spatial Learning2004
- Author(s)
  Li ST, et al.
- Journal Title
  
  Annals of Neurology 55,3
  
  Pages: 362-371
- Data Source
  KAKENHI-PROJECT-15790117
[Journal Article] Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.2004
- Author(s)
  Wu HY, Tomizawa K, Oda Y, Wei FY, Lu YF, Matsushita M, Li ST, Moriwaki A, Matsui H.
- Journal Title
  
  J Biol Chem. Feb 6;279(6)
  
  Pages: 4929-4940
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Lp3/Hapln3, a novel link protein which colocalizes with versican and is coordinately upregulated by platelet-derived growth factor in arterial smooth muscle cells2004
- Author(s)
  Ogawa H, Oohashi T, Sata S, Bekku Y, Hirohata S, Nakamura K, Yonezawa T, Kusachi S, Shiratori Y, Ninomiya Y
- Journal Title
  
  Matrix Biol. 23
  
  Pages: 287-298
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591857
[Journal Article] HIV-1 Tat inhibits long-term potentiation and attenuates spatial learning.2004
- Author(s)
  Li ST, Matsushita M, Moriwaki A, Saheki Y, Lu YF, Tomizawa K, Wu HY, Terada H, Matsui H.
- Journal Title
  
  Ann Neurol. Mar;55(3)
  
  Pages: 362-371
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] HIV-1 tat inhibits long-term potentiation and attenuates spatial learning.2004
- Author(s)
  Li, S.-T., Matsushita, M., Tomizawa, K., Matsui, H.
- Journal Title
  
  Ann.Neurol 55
  
  Pages: 362-371
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390064
[Journal Article] Oxytocin improves long-lasting spatial memory during motherhood through MAP kinase cascade.2003
- Author(s)
  Tomizawa K, Iga N, Lu YF, Moriwaki A, Matsushita M, Li ST, Miyamoto O, Itano T, Matsui H.
- Journal Title
  
  Nat Neurosci. Apr;6(4)
  
  Pages: 384-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Oxytocin improves long-lasting spatial memory during motherhood through MAP kinase cascade.2003
- Author(s)
  Tomizawa K, Iga N, Lu YF, Moriwaki A, Matsushita M, Li ST, Miyamoto O, Itano T, Matsui H
- Journal Title
  
  Nat Neurosci. 6,4
  
  Pages: 384-390
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity.2002
- Author(s)
  Tomizawa K, Ohta J, Matsushita M, Moriwaki A, Li ST, Takei K, Matsui H.
- Journal Title
  
  J Neurosci. Apr 1;22(7)
  
  Pages: 2590-2597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Cdk5/p35 regulates neurotransmitter release through phosphorylation and downregulation of P/Q-type voltage-dependent calcium channel activity2002
- Author(s)
  Tomizawa K, Ohta J, Matsushita M, Moriwaki A, Li ST, Takei K, Matsui H
- Journal Title
  
  J Neurosci 22,7
  
  Pages: 2590-2597
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells.2002
- Author(s)
  Takenobu T, Tomizawa K, Matsushita M, Li ST, Moriwaki A, Lu YF, Matsui H
- Journal Title
  
  Mol Cancer Ther 1,12
  
  Pages: 1043-1049
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Development of p53 protein transduction therapy using membrane-permeable peptides and the application to oral cancer cells.2002
- Author(s)
  Takenobu T, Tomizawa K, Matsushita M, Li ST, Moriwaki A, Lu YF, Matsui H.
- Journal Title
  
  Mol Cancer Ther. Oct;1(12)
  
  Pages: 1043-1049
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Calcineurin plays different roles in group II metabotropic glutamate receptor- and NMDA receptor-dependent long-term depression.2002
- Author(s)
  Li ST, Kato K, Tomizawa K, Matsushita M, Moriwaki A, Matsui H, Mikoshiba K
- Journal Title
  
  J Neurosci. 15,22
  
  Pages: 5034-5041
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] Calcineurin plays different roles in group II metabotropic glutamate receptor-and NMDA receptor-dependent long-term depression2002
- Author(s)
  Li ST, Kato K, Tomizawa K, Matsushita M, Moriwaki A, Matsui H, Mikoshiba K.
- Journal Title
  
  J Neurosci. Jun 15;22(12)
  
  Pages: 5034-5041
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570059
[Journal Article] A new cell-permeable peptide allows successful allogeneic islet transplantation in mice.
- Author(s)
  Noguchi H, Matsushita M, Okitsu T, Moriwaki A, Tomizawa K, Kang S, Li ST, Kobayashi N, Matsumoto S, Tanaka K, Tanaka N, Matsui H
- Journal Title
  
  Nat Med 10,3
  
  Pages: 305-309
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570059

1. TOMIZAWA Kazuhito (40274287)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
2. MATSUI Hideki (30157234)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
3. MORIWAKI Akiyoshi (10144742)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
4. MATSUSHITA Masayuki (30273965)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
5. OMOTO Takashi (60032900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OOHASHI Toshitaka (50194262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. NINOMIYA Yoshifumi (70126241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 近藤英作 (30252951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 陸雲飛 (60243458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

RI Syouten 李 勝天

Research Projects

Research Products

Co-Researchers

プレシナプスのカルシニューリンによるシナプス可塑性の制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Imaging and functional regulation of microenvironment in subcellular organelle

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological and electrophyrsiological studies of extranodal matrices on the saltatory conduction of the optic nerve

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Translational regulation of vasopressin synthesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

蛋白質セラピー法による興奮性ニューロン死の防止と新しい脳保護薬創出の試み

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of Calpain-mediated Cleavage of Calcineurin in Excitotoxic Neurodegeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE MECHANlSM OF LAIE-PHASE LTP INDUCTION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of Ca2+ ion inflow regulated by KF506 binding proteins (FKBP) and Calcineurin.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] A new cell-permeable peptide allows successful allogeneic islet transplantation in mice.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] HIV-1 tat inhibits long-term potentiation and attenuates spatial learning.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] HIV-1 Tat Inhibits Long-Term Potentiation and Attenuates Spatial Learning2004

Author(s)

Journal Title

Data Source

[Journal Article] Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Lp3/Hapln3, a novel link protein which colocalizes with versican and is coordinately upregulated by platelet-derived growth factor in arterial smooth muscle cells2004

Author(s)

Journal Title

Description

RI Syouten 李勝天