MIYASAKA Tomohiro 宮坂知宏

… Alternative Names

宮坂知宏ミヤサカトモヒロ

Less

Researcher Number	90342857
Other IDs
Affiliation (Current)	2025: 日本大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 日本大学, 薬学部, 教授 2021 – 2022: 同志社大学, 生命医科学部, 准教授 2016 – 2019: 同志社大学, 生命医科学部, 准教授 2015: 同志社大学, 公私立大学の部局等, 准教授 2014: 同志社大学, 生命医科学部, 准教授 … More 2008 – 2011: Doshisha University, 生命医科学部, 助教 2007: Doshisha University, 生命医科学部・設置準備室, 助教 2006: 東京大学, 大学院医学系研究科, 助手 2003 – 2005: 東京大学, 大学院・医学系研究科, 助手 2004: University of Tokyo, Graduate School of Medicine, Instructor, 大学院医学系研究科, 助手 2001 – 2002: 理化学研究所, アルツハイマー病研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology / Basic Section 51020:Cognitive and brain science-related / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology Except Principal Investigator Biological Sciences / Basic Section 61010:Perceptual information processing-related / Medium-sized Section 61:Human informatics and related fields / Pharmacology in pharmacy / Biological Sciences
Keywords	Principal Investigator タウ / アルツハイマー病 / 線虫 / 認知症 / 微小管 / タウオパチー / 神経細胞死 / チューブリン / RNAi / アルツハイマー … More / 神経変性疾患 / MAPs / 育児行動 / 聴覚障害 / tau / オキシトシン / 育児 / 微小管結合タンパク質 / MAP2 / 創薬 / クルクミン / 神経変性 / Gene Chip / NFT / FIDP-17 / Neurofibrillary Tangle / FTDP-17 / Gene chip / PHF / 原子間力顕微鏡 / Bouin / リン酸化 / 凝集 / 神経原線維変化 … More Except Principal Investigator アルツハイマー病 / タウ / 難聴 / 人工内耳 / JNK / Neurofibrillary tangles / Tau / Alzheimer's disease / 神経原線維変化 / 神経細胞死 / 老化 / Aβ / 感音性難聴 / 神経刺激 / 赤外レーザー / らせん神経節細胞 / レーザー刺激 / 補聴器 / 赤外光レーザー刺激 / 赤外光レーザー / ブレインマシーンインターフェイス / 光刺激 / 脳・神経 / 薬理学 / 薬学 / アルツハイマー型認知症 / Presenilin / Aging / GSK-3 / 行動異常 / マウスモデル / FTDP17 / GSK-3β / FTDP-17 / 痴呆 / 細胞骨格 / プレセニリン / β-アミロイド / 神経原線維 / 神経変性 / Neuronal death / タウ蛋白 / 樹状突起 / 過活動 / 局在 / 脳神経疾患 / 神経科学 / リン酸化 / 凝集 / 脳機能 / 認知症 / タウタンパク質 / ノックインマウス / タウ遺伝子 / 神経原繊維変化 / 細胞・組織 Less

Optical control of auditory pathway for next generation auditory prosthesis
- Principal Investigator
  
  小林耕太
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 61:Human informatics and related fields
- Research Institution
  Doshisha University
微小管結合タンパク質の機能損失が個体間コミュニケーションに与える影響Principal Investigator
- Principal Investigator
  
  宮坂知宏
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Nihon University
  Doshisha University
近赤外レーザーを用いた次世代人工内耳の開発と評価
- Principal Investigator
  
  小林耕太
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 61010:Perceptual information processing-related
- Research Institution
  Doshisha University
Development of novel therapeutic agents for Alzheimer's disease based on analysis of neuroprotective signals and regulation of tau phosphorylation
- Principal Investigator
  
  Takada-Takatori Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Mechanism of tau protein aging and neurodegeneration
- Principal Investigator
  
  Takashima Akihiko
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gakushuin University
  National Center for Geriatrics and Gerontology
Development of anti-tauopathy drugs using C. elegans.Principal Investigator
- Principal Investigator
  
  MIYASAKA Tomohiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Doshisha University
Imbalanced expression of tau and tubulin is an essential step for pathogenesis of tauopathy.Principal Investigator
- Principal Investigator
  
  MIYASAKA Tomohiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Doshisha University
線虫モデルを用いたタウオパチー神経変性機構の解明と治療法の探索Principal Investigator
- Principal Investigator
  
  宮坂知宏
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Doshisha University
  The University of Tokyo
変異型タウ遺伝子導入によるヒト痴呆疾患モデルマウスの作製と解析
- Principal Investigator
  
  佐藤隆史
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
線虫モデルを用いたタウオパチー神経変性機構の解明Principal Investigator
- Principal Investigator
  
  宮坂知宏
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  The University of Tokyo
アルツハイマー病脳における異常タウと神経細胞死の解明Principal Investigator
- Principal Investigator
  
  宮坂知宏
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  The University of Tokyo
  The Institute of Physical and Chemical Research
Mechanism of NFT formation
- Principal Investigator
  
  TAKASHIMA Akihiko
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  RIKEN
Hyperphosphorylation and aggregation of tau protein, and neuronal death
- Principal Investigator
  
  IHARA Yasuo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo

[Journal Article] Mass Spectrometry Imaging in Alzheimer's Disease2023
- Author(s)
  Ikegawa Masaya、Kakuda Nobuto、Miyasaka Tomohiro、Toyama Yumiko、Nirasawa Takashi、Minta Karolina、Hanrieder Jorg
- Journal Title
  
  Brain Connectivity
  
  Volume: - Issue: 6 Pages: 319-333
- DOI
  10.1089/brain.2022.0057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24207
[Journal Article] The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives2023
- Author(s)
  Yoshimura Rikuya、Miyasaka Tomohiro、Funamoto Satoru、Saito Takashi、Saido Takaomi C.、Ikegawa Masaya、Kakuda Nobuto
- Journal Title
  
  Brain and Behavior
  
  Volume: 13 Issue: 4 Pages: 1-4
- DOI
  10.1002/brb3.2953
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06466, KAKENHI-PROJECT-23K24207
[Journal Article] Quantitative Microtubule Fractionation Technique to Separate Stable Microtubules, Labile Microtubules, and Free Tubulin in Mouse Tissues2023
- Author(s)
  Hagita-Tatsumoto Ayaka、Miyasaka Tomohiro
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: - Issue: 201
- DOI
  10.3791/63358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24207
[Journal Article] Identification of Tau protein as a novel marker for maturation and pathological changes of oligodendrocytes2022
- Author(s)
  Torii Tomohiro、Miyamoto Yuki、Nakata Rinaho、Higashi Yuto、Shinmyo Yohei、Kawasaki Hiroshi、Miyasaka Tomohiro、Misonou Hiroaki
- Journal Title
  
  Glia
  
  Volume: 71 Issue: 4 Pages: 1002-1017
- DOI
  10.1002/glia.24322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-20H05056, KAKENHI-PROJECT-23K24207, KAKENHI-PROJECT-21K19306, KAKENHI-PROJECT-20H03338
[Journal Article] Microtubule assembly by tau impairs endocytosis and neurotransmission via dynamin sequestration in Alzheimer's disease synapse model2022
- Author(s)
  Hori, T., Eguchi, K., Wang, H.Y., Miyasaka, T., Guillaud, L., Taoufiq, Z., Mahapatra, S., Yamada, H., Takei, K., Takahashi, T.
- Journal Title
  
  Elife
  
  Volume: 11 Pages: 1-20
- DOI
  10.7554/elife.73542
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03225, KAKENHI-PROJECT-21K06445, KAKENHI-PROJECT-21K19484, KAKENHI-PROJECT-21K07554, KAKENHI-PROJECT-20K08591, KAKENHI-PROJECT-23K24207
[Journal Article] The organization of microtubules and Tau in oligodendrocytes: Tau pathology in damaged oligodendrocytes2022
- Author(s)
  Torii Tomohiro、Miyasaka Tomohiro、Misonou Hiroaki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10
- DOI
  10.3389/fcell.2022.950682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24207
[Journal Article] Quantum-dot-labeled synuclein seed assay identifies drugs modulating the experimental prion-like transmission2022
- Author(s)
  Imamura Yukio、Okuzumi Ayami、Yoshinaga Saki、Hiyama Akiko、Furukawa Yoshiaki、Miyasaka Tomohiro、Hattori Nobutaka、Nukina Nobuyuki
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 1-15
- DOI
  10.1038/s42003-022-03590-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21587, KAKENHI-PROJECT-22K19389, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-19K16928, KAKENHI-PLANNED-19H05765, KAKENHI-PROJECT-23K24207
[Journal Article] Visualization of Amyloid beta Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry2019
- Author(s)
  Ikegawa Masaya、Nirasawa Takashi、Kakuda Nobuto、Miyasaka Tomohiro、Kuzuhara Yuki、Murayama Shigeo、Ihara Yasuo
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 145 Issue: 145
- DOI
  10.3791/57645
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-19K09242
[Journal Article] Distribution of endogenous normal tau in the mouse brain2018
- Author(s)
  Kubo Atsuko、Misonou Hiroaki、Matsuyama Makoto、Nomori Akane、Wada-Kakuda Satoko、Takashima Akihiko、Kawata Mitsuhiro、Murayama Shigeo、Ihara Yasuo、Miyasaka Tomohiro
- Journal Title
  
  Journal of Comparative Neurology
  
  Volume: 527 Issue: 5 Pages: 985-998
- DOI
  10.1002/cne.24577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-18H05414
[Journal Article] Imbalanced Expression of Tau and Tubulin Induces Neuronal Dysfunction in C. elegans Models of Tauopathy.2018
- Author(s)
  Miyasaka T, Shinzaki Y, Yoshimura S, Yoshina S, Kage-Nakadai E, Mitani S, Ihara Y.
- Journal Title
  
  Front Neurosci.
  
  Volume: 12 Pages: 415-415
- DOI
  10.3389/fnins.2018.00415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10998, KAKENHI-PROJECT-17K18135, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16H05123
[Journal Article] Distribution of oxidized DJ-1 in Parkinson’s disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin2018
- Author(s)
  Mita Yuichiro、Kataoka Yuto、Saito Yoshiro、Kashi Takuma、Hayashi Kojiro、Iwasaki Asa、Imanishi Takanori、Miyasaka Tomohiro、Noguchi Noriko
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 12056-12056
- DOI
  10.1038/s41598-018-30561-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16K18707, KAKENHI-PROJECT-17H03821
[Journal Article] Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.2018
- Author(s)
  Tuerde, D., Kimura, T., Miyasaka, T., Furusawa, K., Shimozawa, A., Hasegawa, M., Ando, A., Hisanaga, S.
- Journal Title
  
  J. Biol, Chem.
  
  Volume: 293 Issue: 5 Pages: 1781-1793
- DOI
  10.1074/jbc.m117.798918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07060, KAKENHI-PROJECT-17K07113, KAKENHI-PLANNED-26117004, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-17J06398
[Journal Article] Distinct deposition of amyloid-β species in brains with Alzheimer's disease pathology visualized with MALDI imaging mass spectrometry.2017
- Author(s)
  Kakuda N, Miyasaka T, Iwasaki N, Nirasawa T, Wada-Kakuda S, Takahashi-Fujigasaki J, Murayama S, Ihara Y, Ikegawa M.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 5 Issue: 1 Pages: 73-73
- DOI
  10.1186/s40478-017-0477-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16H06277
[Journal Article] The role of the carboxyl-terminal sequence of tau and MAP2 in the pathogenesis of dementia.2016
- Author(s)
  Xie C, Miyasaka T.
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 9 Pages: 158-158
- DOI
  10.3389/fnmol.2016.00158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004
[Journal Article] Imaging Mass Spectrometry for the Research of Alzheimer’s Disease2016
- Author(s)
  Ikegawa M, Miyasaka T, Kakuda N, Ihara Y
- Journal Title
  
  Journal of the Mass Spectrometry Society of Japan
  
  Volume: 64 Issue: 1 Pages: 17-20
- DOI
  10.5702/massspec.S16-04
- NAID
  130005125536
- ISSN
  1340-8097, 1880-4225, 1884-3271
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117004
[Journal Article] Drug discovery focused on the pathological mechanisms of tauopathy.2016
- Author(s)
  Miyasaka T.
- Journal Title
  
  Proceeding of the Annual Meeting of the Japanese Research Group on Senile Dementia
  
  Volume: 21 Pages: 1-5
- Open Access
- Data Source
  KAKENHI-PLANNED-26117004
[Journal Article] Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau.2015
- Author(s)
  Xie C, Soeda Y, Shinzaki Y, In Y, Tomoo K, Ihara Y, Miyasaka T.
- Journal Title
  
  J Neurochem
  
  Volume: 135 Issue: 1 Pages: 19-26
- DOI
  10.1111/jnc.13228
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26117004
[Journal Article] Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.2015
- Author(s)
  Soeda Y, Yoshikawa M, Almeida OF, Sumioka A, Maeda S, Osada H, Kondoh Y, Saito A, Miyasaka T, Kimura T, Suzuki M, Koyama H, Yoshiike Y, Sugimoto H, Ihara Y, Takashima A
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 10216-10216
- DOI
  10.1038/ncomms10216
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350976, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-25242070, KAKENHI-PROJECT-25460147
[Journal Article] Microtubule destruction induces tau liberation and its subsequent phosphorylation2010
- Author(s)
  Miyasaka T, Sato S, Tatebayashi Y, Takashima A
- Journal Title
  
  FEBS Letters
  
  Volume: 584 Pages: 3227-3232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650074
[Journal Article] Microtubule destruction induces tau liberation and its subsequent phosphorylation.2010
- Author(s)
  T.Miyasaka
- Journal Title
  
  FEBS Letters
  
  Volume: 584 Pages: 3227-3232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650074
[Journal Article] Anesthesia-induced hyperphosphorylation detaches 3-repeat tau from microtubules without affecting their stability in vivo: Tau hyperphosphorylation and microtubules stability in vivo.2008
- Author(s)
  Planel E, Krishnamurthy P, Miyasaka T, Liu L, Herman M, Kumar A, Bretteville A, Figueroa HY, Yu WH, Whittington RA, Davies P, Takashima A, Nixon RA, Duff KE.
- Journal Title
  
  J Neurosci vol.28
  
  Pages: 12798-12807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700324
[Journal Article] Visualization of newly deposited tau in Neurofibrillary tangles and neuropil threads.2005
- Author(s)
  Tomohiro Miyasaka et al.
- Journal Title
  
  Journal of Neuropathology and Experimental Neurology 64・8
  
  Pages: 665-674
- Data Source
  KAKENHI-PROJECT-16700303
[Journal Article] Progressive neurodegeneration in C. elegans model of tauopathy.2005
- Author(s)
  Miyasaka T, et al.
- Journal Title
  
  Neurobiol Dis 20
  
  Pages: 372-383
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Progressive neurodegeneration in C.elegans model of tauopathy.2005
- Author(s)
  Miyasaka T, Ding Z, Gengyo-Ando K, Oue M, Yamaguchi H, Mitani S, Ihara Y
- Journal Title
  
  Neurobiol Dis 20
  
  Pages: 372-383
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Progressive neurodegeneration in C.elegans model of tauopathy2005
- Author(s)
  Miyasaka et al.
- Journal Title
  
  Neurobiology of Disease (in press)
- Data Source
  KAKENHI-PROJECT-16700303
[Journal Article] Progressive neurodegeneration in C.elegans model of tauopathy2005
- Author(s)
  Miyasaka et al.
- Journal Title
  
  Neurobiol Dis (印刷中)
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads.2005
- Author(s)
  Miyasaka T, Watanabe A, Saito Y, Murayama S, Mann DMA, Yamazaki M, Ravid R, Morishima-Kawashima M, Nagashima K, Ihara Y
- Journal Title
  
  J Neuropathol Exp Neurol 64
  
  Pages: 665-674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads.2005
- Author(s)
  Miyasaka T, et al.
- Journal Title
  
  J Neuropathol Exp Neurol 64
  
  Pages: 665-674
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Progressive neurodegeneration in C. elegans model of tauopathy2005
- Author(s)
  Tomohiro Miyasaka et al.
- Journal Title
  
  Neurobiology of Disease 20・2
  
  Pages: 372-383
- Data Source
  KAKENHI-PROJECT-16700303
[Journal Article] Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation : mechanism and implications for Alzheimer's disease.2004
- Author(s)
  Planel E, Miyasaka T, Launey T, Chui D-H, Tanemura K, Sato S, Murayama O, Ishiguro K, Tatebayashi Y, Takashima A.
- Journal Title
  
  J.Neurosci 24
  
  Pages: 2401-2411
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210147
[Journal Article] Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau2002
- Author(s)
  Tatebayashi, Y.Miyasaka, T, Chui, D-H, Akagi, T., Mishima, K., Iwasaki, K., Fujiwara, M., Tanemura, K., Murayama, M., Ishiguro, K., Planel, E., Sato, S., Hashikawa, T., Takashima, A.
- Journal Title
  
  Proc Natl Acad Sci U S A. 99
  
  Pages: 13896-13901
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210147
[Journal Article] Aberrant tau phosphorylation by GSK-3β and JNK-3 induces oligomeric tau fibrils in COS-7 cells2002
- Author(s)
  Sato, S, Tatebayashi, Y., Akagi, T., Chui, D-H, Murayama, M., Miyasaka, T., Planel, E., Tanemura, K., Sun, X, Hashikawa, T., Yoshioka, K., Ishiguro, K., Takashima, A.
- Journal Title
  
  JBC 277
  
  Pages: 42060-42065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13210147
[Journal Article] Selective deposition of mutant tau in the FTDP-17 brain affected by the P301L mutation.2001
- Author(s)
  Miyasaka T, Morishima-Kawashima M, Ravid R, Kamphorst W, Nagashima, K, Ihara Y
- Journal Title
  
  J Neuropathol Exp Neurol 60
  
  Pages: 872-884
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Selective deposition of mutant tau in the FTDP-17 brain affected by the P301L mutation.2001
- Author(s)
  Miyasaka T, et al.
- Journal Title
  
  J Neuropathol Exp Neurol 60
  
  Pages: 872-884
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Molecular analysis of mutant and wild-type tau deposited in the brain affected by FTDP-17 R406W mutation.2001
- Author(s)
  Miyasaka T, Morishima-Kawashima M, Ravid R, Heutink P, van Swieten JC, Nagashima K, Ihara Y
- Journal Title
  
  Am J Pathol 158
  
  Pages: 373-379
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Molecular analysis of mutant and wild-type tau deposited in the brain affected by FTDP-17 R406W mutation.2001
- Author(s)
  Miyasaka T, et al.
- Journal Title
  
  Am J Pathol 158
  
  Pages: 373-379
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Patent] 2,4-ジアミノフェノール誘導体、及び、タウ及び／又はアミロイドβの凝集阻害剤2017
- Inventor(s)
  宮坂知宏、杉本八郎、井上善一他4名
- Industrial Property Rights Holder
  同志社大学
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-08
- Overseas
- Data Source
  KAKENHI-PLANNED-26117004
[Patent] 灌流用注射針2016
- Inventor(s)
  宮坂知宏、久保厚子
- Industrial Property Rights Holder
  同志社大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-08-22
- Overseas
- Data Source
  KAKENHI-PLANNED-26117004
[Patent] イメージング質量分析の前処理方法2016
- Inventor(s)
  池川雅哉、宮坂知宏、角田伸人、韮沢崇
- Industrial Property Rights Holder
  同志社大学、ブルカー・ダルトニクス株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-231372
- Filing Date
  2016-11-29
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] 生理的条件下における遊離型タウ結合因子の同定2023
- Author(s)
  辰本彩香、渡邉淳、宮坂知宏
- Organizer
  第６６回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] タウの生理的なプロテオスタシスの破綻が認知症発症のカギとなる2023
- Author(s)
  Tomohiro Miyasaka
- Organizer
  第６６回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] 概日リズムとアルツハイマー病2023
- Author(s)
  久保厚子、長野護、宮坂知宏、重吉康史
- Organizer
  第４６回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] 新規難聴原因遺伝子 MAP2 の生理機能：オペラント条件づけを用いた MAP2 ノックアウトマウスの兆アック特性計測2023
- Author(s)
  福沢恵美、新家一樹、伊藤優樹、宮坂知宏、原田彰宏、小林耕太
- Organizer
  第４６回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] 軸索局在をもたらす Tau 発現の臨界期解析2023
- Author(s)
  上田遼之、山本亮良、大石康二、元山純、宮坂知宏
- Organizer
  第６６回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] マウス脳におけるタウの局所濃度決定方法の確立2023
- Author(s)
  前田希、堀琴和、大江洋平、宮坂知宏
- Organizer
  第６６回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] Does loss of MAP2 function affect sound perception? Measureing auditory characteristics using operant conditioning2023
- Author(s)
  Emi FUkuzawa, Kazuki Shin'ya, Misaki Takaoka, Yuki Ito, Tomohiro Miyasaka, Nobut Kakuda, Akihiro Harada, Khota Kobayashi
- Organizer
  IBAC2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] The novel gene responsible for non-syndromic sensorineural hearing loss: measurement of auditory characteristics of MAP2 knockout mice using operant conditioning2023
- Author(s)
  Emi Fukuzawa, Kazuki Shin'ya, Yuki Ito, Tomohiro Miyasaka, Nobuto Kakuda, Akihiro Harada, Kohta I Kobayashi
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-23K21682
[Presentation] Does loss of MAP2 function affect sound perception? - Measuring auditory characteristics using operant conditioning2023
- Author(s)
  Emi Fukuzawa ，Kazuki Shin’ya, Misaki Takaoka, Yuki Ito, Tomohiro Miyasaka, Nobuto Kakuda, Akihiro Harada, Kohta I Kobayasi
- Organizer
  XXVIII International Bioacoustics Congress
- Data Source
  KAKENHI-PROJECT-23K21682
[Presentation] 赤外光レーザー人工内耳の実現可能性：経鼓膜レーザー刺激が誘発する知覚の評価2022
- Author(s)
  上中望生, 玉井湧太, 岡本彩, 細川慶人, 伊藤優樹, 宮坂知宏, 兎田幸司, 飛龍志津子, 小林耕太
- Organizer
  第99回日本生理学会大会@オンライン
- Data Source
  KAKENHI-PROJECT-23K21682
[Presentation] タウ/MAP2二重欠損マウスが呈する育児行動障害に対するオキシトシンの効果2022
- Author(s)
  宮坂知宏, 謝策, 矢口花紗音, 植田結稀, 佐久間浩平, 堀部麻子, 原田彰宏
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] 経鼓膜レーザー刺激が誘発する聴知覚の評価2022
- Author(s)
  上中望生, 岡本彩, 細川慶人, 伊藤優樹, 宮坂知宏, 兎田幸司, 飛龍志津子, 小林耕太, 玉井湧太
- Organizer
  第12回東京若手心理学者の会
- Data Source
  KAKENHI-PROJECT-23K21682
[Presentation] MAP2の消失が聴覚末梢系の情報伝達に与える影響2022
- Author(s)
  田中一樹, 宮坂知宏, 原田彰宏, 小林耕太
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-23K24207
[Presentation] アルツハイマー病治療薬による過剰タウリン酸化抑制作用2019
- Author(s)
  髙島　小波，髙鳥　悠記，高良　香葉子，野々口　茉奈，庄野　七海子，泉　安彦，赤池　昭紀，宮坂　知宏，久米　利明，土田　勝晴
- Organizer
  第69回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08323
[Presentation] 低温負荷による脳内タウの過剰リン酸化に対するドネペジルの作用2019
- Author(s)
  高良　香葉子、髙鳥　悠記、髙島　小波、中西　涼介、泉　安彦、赤池　昭紀、宮坂　知宏、久米　利明、土田　勝晴
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08323
[Presentation] Donepezil decreases tau hyperphosphorylation induced by hypothermia in vivo and in vitro2019
- Author(s)
  Ryosuke Nakanishi, Yuki Takada-Takatori, Kayoko Takara, Konami Takashima, Katsuharu Tsuchida, Yasuhiko Izumi, Akinori Akaike, Tomohiro Miyasaka, Toshiaki Kume
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08323
[Presentation] In vitro disease modeling of the FTDP-17 TAU R406W mutation using patient-derived iPSCs.2018
- Author(s)
  Nakamura M, Watanabe H, Shiozawa S, Maeda S, Hisanaga SI, Sahara N, Kimura T, Miyasaka T, Takashima A, Ikeuchi T, Okano H
- Organizer
  Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] タウisoformの成体神経新生における役割2018
- Author(s)
  石垣診祐、岩出展行、藤岡祐介、遠藤邦幸、河合香里、石橋みなか、勝野雅央、渡辺宏久、宮坂知宏、祖父江元
- Organizer
  第13回　臨床ストレス応答学会大会
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Tubulin degeneration induces tau abnormalities2018
- Author(s)
  Fujiwara H, Watanabe S, Iwata M, Nobuhara M, Wada-Kakuda S, Misonou H, Miyasaka T
- Organizer
  Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] tbcEノックダウンによるチューブリン変性を介したタウ異常性の獲得2018
- Author(s)
  藤原ひとみ、渡辺祥司、岩田実里、上田翔洋、和田聡子、延原美香、御園生裕明、宮坂知宏
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Tubulin degeneration causes tau abnormalities2018
- Author(s)
  藤原ひとみ，渡辺祥司，岩田実里，上田翔洋，延原美香，和田聡子，御園生裕明，宮坂知宏
- Organizer
  第61回日本神経化学会
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] The study of axonal localization mechanisms of tau in neuron2018
- Author(s)
  Iwata M, Watanabe S,Miyasaka T, Misonou H
- Organizer
  Neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.2017
- Author(s)
  Tuerde D, Kimura T, Miyasaka T, Furusawa K, Shimozawa A, Hasegawa M, Ando K, Hisanaga S.
- Organizer
  The International Society of Neurochemistry (ISN) and the European Society for Neurochemistry (ESN)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Isoform-independent and -dependent phosphorylation of microtubule-associated protein tau in mouse brain during postnatal development.2017
- Author(s)
  Tuerde D, Kimura T, Miyasaka T, Furusawa K, Shimozawa A, Hasegawa M, Ando K, Hisanaga S.
- Organizer
  Cell symposium: Big question in Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] 脳発生に伴うタウ関連タンパク質の発現変化2016
- Author(s)
  上田翔洋、角田聡子、久保厚子、宮坂知宏
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Phosphorylation and Isoform Expression of Microtubule-Associated Protein Tau are Regulated Independently during Brain Development.2016
- Author(s)
  Tuerde D, Kimura T, Miyasaka T, Asada A, Saito1 T, Ando, K, Hisanaga S.
- Organizer
  Asian-Pacific Society for Neurochemistry
- Place of Presentation
  クアラルンプール、マレーシア
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] 神経細胞におけるアルツハイマー病原因蛋白質タウの軸索局在の分子機序2016
- Author(s)
  岩田美里、渡邊祥司、宮坂知宏、朴洪宣、御園生裕明
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] 神経細胞におけるタウ蛋白質の軸索局在化機構の解明2016
- Author(s)
  岩田美里、渡邊祥司、宮坂知宏、朴洪宣、御園生裕明
- Organizer
  第35回日本認知症学会学術集会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Distribution of endogenous and exogenous tau in the mouse brain2015
- Author(s)
  Atsuko Kubo, Hiroaki Misonou, Makoto Matsuyama, Akihiko Takashima, Yasuo Ihara, Tomohiro Miyasaka
- Organizer
  The 12th International Conference on Alzheimer's and Parkinson's Diseases
- Place of Presentation
  Nice, France
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] 正常脳におけるタウの神経細胞内局在2014
- Author(s)
  久保厚子、御園生裕明、松田響子、松山誠、河田光博、初田裕幸、村山繁雄、井原康夫、宮坂知宏
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-30
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] tau-Tg マウス脳における内在性および外来性タウの神経細胞内局在2014
- Author(s)
  久保厚子、御園生裕明、松山誠、高島明彦、井原康夫、宮坂知宏
- Organizer
  第33回日本認知症学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-12-01
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] マウス脳における内在性および外来性 tau の局在2014
- Author(s)
  久保厚子、御園生裕明、松山誠、高島明彦、井原康夫、宮坂知宏
- Organizer
  第37回日本神経科学大会 Neuroscience 2014
- Place of Presentation
  横浜市
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PLANNED-26117004
[Presentation] Imbalanced expression of tau and tubulin may be a determinant of the tauopathy cascade2010
- Author(s)
  Miyasaka T, Shinzaki Y, Yoshimura S, Yoshina S, Kage-Nakadai E, Mitani S, Ihara Y
- Organizer
  40th Annual meeting, Society for Neuroscience
- Place of Presentation
  SanDiego
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22650074
[Presentation] Imbalanced expression of tau and tubulin may be a determinant of the tauopathy cascade.2010
- Author(s)
  T.Miyasaka
- Organizer
  40th Annual meeting, Society for Neuroscience
- Place of Presentation
  San Diego, Convention center
- Year and Date
  2010-11-15
- Data Source
  KAKENHI-PROJECT-22650074
[Presentation] Curcumin improves tau-mediated neuronal dysfunction in nematode.2010
- Author(s)
  T.Miyasaka
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease (ICAD) 2010
- Place of Presentation
  Honolulu, Convention center
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-22650074
[Presentation] Curcumin improves tau-mediated neuronal dysfunction in nematode2010
- Author(s)
  Miyasaka T, Yoshimura S, Saka A, Shinzaki Y, Yoshina S, Kage-Nakadai E, Mitani S, and Ihara Y
- Organizer
  Alzheimer's Association International Conference on Alzheimer's Disease(ICAD)
- Place of Presentation
  Hawaii
- Year and Date
  2010-07-14
- Data Source
  KAKENHI-PROJECT-22650074
[Presentation] Imbalanced expression of tau and tubulin may be a key step to tauopathy2008
- Author(s)
  Miyasaka T and Ihara Y
- Organizer
  The 15th Takeda Science Foundation Symrosium on Bioscience "Cell Death : what have we learned and what will we learn?"
- Place of Presentation
  東京
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20700324
[Presentation] Imbalanced expression of tau and tubulin may be a key step to tauopathy.2008
- Author(s)
  Miyasaka T, Ihara Y.
- Organizer
  The 15th Takeda Science Foundation Symposium on Bioscience "Cell Death: what have we learned and what will we learn?"
- Place of Presentation
  東京
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20700324
[Presentation] C.elegans model of tauopathy.2007
- Author(s)
  宮坂知宏
- Organizer
  第50回日本神経化学会
- Place of Presentation
  横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-18700349
[Presentation] Proteomic Imaging of amyloids in Brains from Amyloid Precursor Protein (APP) Transgenic Mice in comparison with Human Alzheimer Disease.
- Author(s)
  Masaya Ikegawa, Tomohiro Miyasaka, Noriyuki Iwasaki, Takashi Nirasawa, Hiroyuki Sumikura, Shigeo Murayama, Yasuo Ihara.
- Organizer
  63rd ASMS Conference on Mass Spectrometry and Allied Topics.
- Place of Presentation
  St. Louis, USA
- Year and Date
  2015-05-31 – 2015-06-04
- Data Source
  KAKENHI-PLANNED-26117004

1. 小林耕太 (40512736)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. Takashima Akihiko (00154774)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 飛龍志津子 (70449510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 玉井湧太 (70906627)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 古山貴文 (20802268)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. IHARA Yasuo (60114386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. MORISHIMA Maho (50204722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. FUNAMOTO Satoru (10345043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. ITO Mamoru (00176364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. FUJITA Shinobu (30092323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAHARA Naruhiko (40261185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ISHIZUKA Koko (80373265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Takada-Takatori Yuki (90411090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 佐藤隆史 (70344934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 原田彰宏 (40251441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 久永眞市 (20181092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. 石垣診祐 (40378170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 池川雅哉 (60381943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 元永耕三 (20345044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 山崎恒夫 (80200658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 小山文隆 (40194641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 岡澤均 (50261996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 楯林義孝 (80342814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 種村健太郎 (20332322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
25. 孫小燕 (50312278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 佐藤慎二 (10322702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 久米利明 (10303843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
28. 兎田幸司 (60794948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. Soeda Yoshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. Sumioka Akio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Misonou Hiroaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
32. Taguchi Akiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 崔得華

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. エマヌエルプラネル

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. CHUI De-Hua

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
36. PLANEL Emmanuel

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
37. 催徳華

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. プラネルエマヌエル

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. NAKADAI Eriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. IMAMURA Yukio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 河崎洋志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 竹居孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 山田浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 近藤恭光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 貫名信行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 奥住文美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYASAKA Tomohiro 宮坂 知宏

宮坂 知宏 ミヤサカ トモヒロ

Research Projects

Research Products

Co-Researchers

Optical control of auditory pathway for next generation auditory prosthesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

微小管結合タンパク質の機能損失が個体間コミュニケーションに与える影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

近赤外レーザーを用いた次世代人工内耳の開発と評価

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutic agents for Alzheimer's disease based on analysis of neuroprotective signals and regulation of tau phosphorylation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of tau protein aging and neurodegeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anti-tauopathy drugs using C. elegans.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Imbalanced expression of tau and tubulin is an essential step for pathogenesis of tauopathy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

線虫モデルを用いたタウオパチー神経変性機構の解明と治療法の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

変異型タウ遺伝子導入によるヒト痴呆疾患モデルマウスの作製と解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

線虫モデルを用いたタウオパチー神経変性機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルツハイマー病脳における異常タウと神経細胞死の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of NFT formation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hyperphosphorylation and aggregation of tau protein, and neuronal death

Principal Investigator

Project Period (FY)

MIYASAKA Tomohiro 宮坂知宏

宮坂知宏ミヤサカトモヒロ