ITO Mamoru 伊藤守

Researcher Number	00176364
Other IDs
Affiliation *help	2017 – 2018 : 公益財団法人実験動物中央研究所, 研究部門, 副所長 2016 : 公益財団法人実験動物中央研究所, 研究部門, 研究員 2012 – 2014 : 公益財団法人実験動物中央研究所, その他部局等, 研究員 2011 : (財)実験動物中央研究所, 免疫研究室長 2011 : 公益財団法人実験動物中央研究所, 実験動物研究部, 部長 … More
Review Section/Research Field	Principal Investigator Laboratory animal science / Laboratory animal science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields Except Principal Investigator Laboratory animal science / 寄生虫学(含医用動物学) / Biological Sciences / Hematology / 物質生物化学 / Immunology / 広領域 / 基礎獣医学 / 寄生虫学(含医用動物学）
Keywords	Principal Investigator 実験動物 / 免疫 / ES細胞 / 異種移植 / 免疫不全マウス / 動物モデル / 細胞接着因子 / ヒト化モデル / HIV-1 / China … More Except Principal Investigator Echinococcus / AIDS / 人獣共通感染症 / Zoonosis / テニア科条虫 / エキノコックス / Arthropod-borne Infection / Echinococcus multilocularis / ニューモシスチス・カリニ肺炎 / SCIDマウス / Taenia / RAG1・RAG2 / マウス / Prednisolone / 中央アジア / 系統保存 / 寄生虫 / 免疫不全 / Central Eurasia / ラット / Pneumocystis carinii / positive selection / FLT3 / 日和見感染症 / Trichinella britovi / MAPK / 免疫 / 胸腺細胞 / リーシュマニア症 / Trypanosoma cruzi / Pathogenic protozoa / Schistosoma mansoni / ニューモシスチス・カリニ / スナネズミ / 疾患モデル / Monoclonal Antibody / ファージ・ディスプレー法 / Growth curve / Animal Models for Human Diseases / 南北米産齧歯類 / CD34 / 無脊椎動物媒介性疾患 / エキノコックス症 / Golden hamster / 重症マラリア感受性遺伝子 / ハムスター / 免疫系ヒト化マウス / イヌ / 免疫不全動物 / リンパ節 / Mini-pigs / ヒト癌細胞 / 節足動物媒介性感染症 / antagonistic competition / 分子標的療法 / 薬剤耐性 / タイ国 / 繁殖成績 / トランスジェニックマウス / Heterromydae(ポケットマウス科) / MHC拘束性 / ヒト疾患モデル動物 / taeniid cestode / 虫体ES抗原 / Alternative / 発育比較 / 多包虫 / 中華人民共和国 / MHC class II / 遺伝子再構成 / Schizodeme analysis / Preservation of Strains / ネコ条虫 / American rodents / 補体レセプター1型(CR1) / ロゼット / ribosomal DNA / 熱帯熱マラリア / therapeutic agent / 有鉤嚢虫症 / Tau / 有鉤条虫 / experimental animal model for cysticercosis / 代替動物 / 病態モデル動物 / Trichinella spiralis / Rat / proliferative inhibition / 化学療法薬 / プレドニゾロン / Coproantigen / Dipodomys / 生物防除 / ゴールデンハムスター / Trichimella spiralis / Taenia(テニア属) / 遺伝 / worm-expulsion(虫体排除) / 免疫不全マウス / PCR / ヒト免疫 / 遺伝子診断 / 品質管理 / ヘパラン硫酸 / animal model / 微生物 / 心臓移植 / disease model mice / トランスジエニックマウス / 内臓型リーシュマニア症 / 病原性原虫 / echinococcosis / NK細胞 / ラット系統 / 細胞増殖抑制 / バイオサイエンス / 多包条虫 / ヒト化マウス / TCR / エゾヤチネズミ / Heteromydae(ポケットマウス科) / knock-out mouse / 無鉤条虫 / 重症化 / worm-expulision(虫体排除) / genes related to servere malaria / Mice / ES cells / scid mouse / 有鉤襄虫症 / T cell receptor / Embryos / ハムスタ- / 中央ユーラシア / Mongolian gerbil / アクレアシン / Hamster / トランスジェニック / thymocyte / Perognathus / 内蔵型リーシュマニア症 / faiciparm malaria / 神経細胞死 / alternative(代替動物) / Trypanosoma spp. / ゲノム / 骨髄移植モデル / プリドニゾロン / Strain / CD14 / Transplantation / Molecular Epidemiology / Host specificity / 免疫不全症 / Reproductive performance / Cricetidae / ヒトリンパ球構築 / vole / 疾患モデル系統 / common γchain / transgenic mouse / 熱帯熱マラリア患者 / Irrigation of deserts / ヒト抗体 / NOD mice / カニクイザル / マ-モセット / 胚の凍結保存 / 小型ブタ / Pneumocystis carinii pneumonia / prednisolone(プレドニゾロン) / 皮膚型リーシュマニア症 / gene rearrangement / 疫学 / 糖尿病 / 熱帯マラリア / 生物防除 / マラリア抗原 / irrigation of deserts / Leukemia / T細胞抗原レセプター(TCR) / 消化管粘膜 / Epidemiology / 実験動物モデル / 突然変異 / グルカン / golden hamster(ゴ-ルデンハムスタ-) / ELISA / Molecularly targeted thrapy / アルツハイマー病 / 系統 / 疾患パラメーター / スキッド・マウス / infection kinetic / 生物的防除 / 実験動物 / Leishmaniasis / 抗体 / glucan / Heteromydae / リーシュマニア原虫 / マラリア流行 / Pneumocystis carinii Pneumonia / Immunodiagnosis / aculeacin / Echinococcus(エキノコックス) / 種間競合 / drug resistance / cysticercosis / 変異FLT3 / モニタリング / Embryo Bank / Clethrionomys / 動物実験系 / 免疫診断 / 移植 / T細胞レセプター / IgGクラススイッチ / Opportunistic Infection / human cancer / SCID mouse / NOGマウス / laboratory animal / Taenia saginata / 神経原線維変化 / 代替宿主 / 日和見感染性 / マイクロサテライトマーカー / オオスナネズミ / phage display method / 胸腺 / Taenia solium / germ line転写 / フローサイトメトリー / Worm-expulsion / severe combined immunodeficient (scid)mouse / 実験動物化 / Laboratory Animals / コレステロール / HLA-DRトランスジェニックマウス / エイズモデル動物 / HIV / Alternative host / Neuronal death / immunodeficiency / 砂漠の緑地化 / クローン / 感染動態 / Alzheimer's disease / Trypanosoma grosi / mdx mice / opportunistic infection / ヒト型マウス / immunity / biological control / 免疫系ヒト化NOGマウス / タウ蛋白 / Visceral Leishmaniasis / Thalland / コモンγ鎖 / サル骨髄抑制モデル / モデル動物 / Neurofibrillary tangles / 脳嚢虫症 / 正の選択的分化 / 遺伝子マッピング / 猫条虫 / エンブリオバンク / ヒト免疫系 / 第18染色体 / シスエレメント / 砂漠 / 胚 / Embryo Cryopreservation / dy mice / antibodies / 白血病 / Rats / 分子疫学 / Cricetidae(キヌゲネズミ科) / マラリア抗体 / Great gerbils / Trypanosomagrosi / Cutaneous Leishmaniasis / 筋ジストロフィー / モノクローナル抗体 / negative selection / 宿主特異性 / embryo cloning / マウス重症マラリア / 局所免疫 / ノックアウトマウス / 獲得抵抗性 / mouse severe malaria / マッピング Less

Approaches to standardization of humanized mice by transplanting human hematopoietic stem cells (HSC) and thymus generated from induced pluripotent stem (iPS) cells.Principal InvestigatorOngoing
- Principal Investigator
  
  伊藤守
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Central Institute for Experimental Animals
Development of experimentation systems related to personalized medicine using humanized NOG micePrincipal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Establishment of humanized immune mice and its application for study of human immune system of human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof
- Principal Investigator
  
  SUGAMURA Kazuo
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所)
  Miyagi Cancer Center Research Institute
  Tohoku University
Basic study to establish "humanized animal model" by improvement and modification of severely immunodeficient NOG mousePrincipal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Basic studies on animal model for regenerative medicine using severe immunodeficient mice.Principal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Practical use of cloning technology for NOD and dy disease model mice production
- Principal Investigator
  
  KONO Tomohiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  TOKYO UNIVERSITY OF AGRICULTURE
The studies on the practical application of NOD-sc/d, yc null mice allowing an efficient transplantation of human cells, to human disease modelsPrincipal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Study on their experimetation of gerbils living in China for infectious diseases.Principal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Establishment of a leukemia model mouse by introducing mutated FLT3 gene
- Principal Investigator
  
  NAOE Tomoki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University
Hyperphosphorylation and aggregation of tau protein, and neuronal death
- Principal Investigator
  
  IHARA Yasuo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo
Generation of cloned mice and application on the field of laboratory animal sciencePrincipal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Genomic factors of parasites and human beings on malaria severity
- Principal Investigator
  
  AIKAWA Masamichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Tokai University
Epidemiology and Control of Leishmaniasis in Central Eurasia ; A new epidemic in association with irrigation of deserts
- Principal Investigator
  
  MATSUMOTO Yoshitsugu
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  THE UNIVERSITY OF TOKYO
Development of Chinese Lemming as an Experimental AnimalPrincipal Investigator
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
SEVERE COMBINED IMMUNODEFICIENT (SCID) MICE AS ANIMAL MODELS FOR HUMAN CYSTICERCOSIS AND ECHINOCOCCOSIS (1999)
- Principal Investigator
  
  ITO Akira
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  ASAHIKAWA MEDICAL COLLEGE
Lymphocyte deficient mice as hosts for xenograft of human cells
- Principal Investigator
  
  NAKAMURA Masataka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Tokyo Medical and Dental University
ヒト細胞接着因子導入Tg-SCDIマウスを用いたヒト脳性マラリアモデルの開発Principal Investigator
- Principal Investigator
  
  伊藤守
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Central Institute for Experimental Animals
Molecular mechanism of selective development in thymocytes analysing DP specific molcules
- Principal Investigator
  
  HABU Sonoko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Tokai University
新世界ザルのリンパ球表面抗原に対するモノクローナル抗体の作製とその抗原の機能分析Principal Investigator
- Principal Investigator
  
  伊藤守
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Characterization as experimental animals on mini-pigs in China
- Principal Investigator
  
  TANIOKA Yoshikuni
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Epidemiology and Control of Leishmaniasis in Cetral Eurasia ; A new epidemic in association with irrigation of deserts
- Principal Investigator
  
  MATSUMOTO Yoshitsugu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  The University of Tokyo
ESTABLISHMENT OF ANIMAL MODEL USING SCID MICE FOR ANALYSIS OF DRUG RESISTANCE AGAINST PARSITIC NEECTIONS
- Principal Investigator
  
  KAMIYA Haruo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  HIROSAKI UNIVERSITY
SCIDマウスによるHIV病原性の解析
- Principal Investigator
  
  KOYANAGI Yoshio
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
霊長類によるヒト代替骨髄抑制モデルの開発ならびに造血機能に関する研究
- Principal Investigator
  
  鈴木修三
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
胸腺内分化モデルの確立による自己認識T細胞クローンの選択に関する分子免疫学研究
- Principal Investigator
  
  HABU Sonoko
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokai University
新世界ザルを用いたヒト熱帯熱マラリアモデルの開発Principal Investigator
- Principal Investigator
  
  伊藤守
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Immunological and Genetical Heterogeneity of Pneumocystis carinii
- Principal Investigator
  
  MATSUMOTO Yoshitsugu
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  University of Tokyo
疾患モデル系統における疾患形質パラメーターによる形質モニタリングの確立
- Principal Investigator
  
  KATOH Hideki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Central Institute for Experimental Animals
The standerdization of rat strains for the transplant-immunology and establithment for screening systems of immunosupresive matters
- Principal Investigator
  
  NOMURA Tatsuji
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Gentral Institute for Experimental Animals
Polysaccharide of Pneumocystis carinii cyst wall as a new target for therapy
- Principal Investigator
  
  MATSUMOTO Yoshitsugu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  寄生虫学(含医用動物学）
- Research Institution
  University of Tokyo
ニューモシスティス・カリニ感染に対する防除方法の研究Principal Investigator
- Principal Investigator
  
  伊藤守
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
ESTABLISHMENT AND USE OF ALTERNATIVE DEFINITIVE HOSTS FOR ECHINOCOCCUS
- Principal Investigator
  
  KAMIYA Masao
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  HOKKAIDO UNIVERSITY
Establishment of an Embryo Bank System for Laboratory Animals
- Principal Investigator
  
  NOMURA Tatsuji
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS (CIEA)
Expulsion mechanism of adult-taeniid cestodes induced by mucosal responses of definitive hosts.
- Principal Investigator
  
  KAMIYA Masao
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  基礎獣医学
- Research Institution
  Hokkaido University
Establishment and application of the laboratory colony of Clethrionomys rufocanus bedfordiae susceptible to Echinococcus multilocularis for the antagonistic competion among taeniid species
- Principal Investigator
  
  KAMIYA Masao
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Hokkaido University

[Book] Humanized Mice for HIV Research2015
- Author(s)
  Ito, R. Katano, I. Ito, M.
- Total Pages
  538
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22220007
[Book] Humanized Mice for HIV Research2015
- Author(s)
  Ito, M.
- Total Pages
  538
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-22220007
[Book] LABIO 212014
- Author(s)
  伊藤守
- Total Pages
  2
- Publisher
  公益財団法人日本実験動物協会
- Data Source
  KAKENHI-PROJECT-22220007
[Book] モデル動物利用マニュアルシリーズ「疾患モデルの作製と利用-免疫疾患」2011
- Author(s)
  伊藤守
- Total Pages
  580
- Publisher
  (株)エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22220007
[Book] モデル動物利用マニュアルシリーズ「生体機能モデルと新しいリソース・リサーチツール」2011
- Author(s)
  伊藤守
- Total Pages
  671
- Publisher
  (株)エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22220007
[Book] モデル動物利用マニュアルシリーズ(「生体機能モデルと新しいリソース・リサーチツール」)2011
- Author(s)
  伊藤守
- Total Pages
  671
- Publisher
  (株)エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-22220007
[Journal Article] Predominant Development of Mature and Functional Human NK Cells in a Novel Human IL-2–Producing Transgenic NOG Mouse.2015
- Author(s)
  Katano, I. Takahashi, T. Ito, R. Kamisako, T. Mizusawa, T. Ka, Y. Ogura, T. Suemizu, H. Kawakami, Y. Ito, M.
- Journal Title
  
  J Immunol.
  
  Volume : 194 Pages : 3513-3525
- DOI
  10.4049/jimmunol.1401323
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-26221005, KAKENHI-PROJECT-25430099, KAKENHI-PROJECT-26290034
[Journal Article] Visualization of the human CD4+ T-cell response in humanized HLA-DR4-expressing NOD/Shi-scid/γc(null) (NOG) mice by retrogenic expression of the human TCR gene.2015
- Author(s)
  Takahashi, T. Katano, I. Ito, R. Ito, M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume : 456 Pages : 219-224
- DOI
  10.1016/j.bbrc.2014.11.062
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-25430099, KAKENHI-PROJECT-26290034
[Journal Article] Effective expansion of engrafted human hematopoietic stem cells in bone marrow of mice expressing human Jagged1.2014
- Author(s)
  Negishi, N. Suzuki, D. Ito, R. Irie, N. Matsuo, K. Yahata, T. Nagano, K. Aoki, K. Ohya, K. Hozumi, K. Ando, K. Tamaoki, N. Ito, M. Habu, S.
- Journal Title
  
  Experimental Hematoogy.
  
  Volume : 42 Pages : 487-94
- DOI
  10.1016/j.exphem.2014.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-24590361, KAKENHI-PROJECT-25430099
[Journal Article] APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model.2014
- Author(s)
  Sato, K. Takeuchi, J. S. Misawa, N. Izumi, T. Kobayashi, T. Kimura, Y. Iwami, S. Takaori-Kondo, A. Hu, W. S. Aihara, K. Ito, M. An, D. S. Pathak, V. K. Koyanagi, Y.
- Journal Title
  
  PLOS Pathogens
  
  Volume : 10
- DOI
  10.1371/journal.ppat.1004453
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-24115008, KAKENHI-PROJECT-24390112, KAKENHI-PROJECT-26670168
[Journal Article] NOD-Rag2(null) IL-2Rgamma(null) Mice: An Alternative to NOG Mice for Generation of Humanized Mice2014
- Author(s)
  Katano, I. Ito, R. Kamisako, T. Eto, T. Ogura, T. Kawai, K. Suemizu, H. Takahashi, T. Kawakami, Y. Ito, M.
- Journal Title
  
  Exp Anim
  
  Volume : 63 Pages : 321-30
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007
[Journal Article] Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice.2014
- Author(s)
  Matsushita, H. Yahata, T. Sheng, Y. Nakamura, Y. Muguruma, Y. Matsuzawa, H. Tanaka, M. Hayashi, H. Sato, T. Damdinsuren, A. Onizuka, M. Ito, M. Miyachi, H. Pandolfi, P. P. Ando, K.
- Journal Title
  
  PLOS ONE
  
  Volume : 9
- DOI
  10.1371/journal.pone.0111082
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-24590361, KAKENHI-PROJECT-24591411, KAKENHI-PROJECT-26430094
[Journal Article] Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells.2013
- Author(s)
  Hirose, S., N. Takayama, S. Nakamura, K. Nagasawa, K. Ochi, S. Hirata, S. Yamazaki, T. Yamaguchi, M. Otsu, S. Sano, N. Takahashi, A. Sawaguchi, M. Ito, T. Kato, H. Nakauchi, and K. Eto.
- Journal Title
  
  Stem Cell Reports
  
  Volume : 1 Issue : 6 Pages : 499-508
- Publisher
  Elsevier Inc.
- DOI
  10.1016/j.stemcr.2013.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Establishment of a human allergy model using human IL-3/GM-CSF transgenic NOG mice2013
- Author(s)
  Ito, R., T. Takahashi, I. Katano, K. Kawai, T. Kamisako, T. Ogura, M. Ida-Tanaka, H. Suemizu, S. Nunomura, C. Ra, A. Mori, S. Aiso, and M. Ito.
- Journal Title
  
  Journal of Immunology
  
  Volume : 191 Pages : 2890-2899
- DOI
  10.4049/jimmunol.1203543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-23590561, KAKENHI-PROJECT-25430099
[Journal Article] Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome2013
- Author(s)
  Saida, S., K. Watanabe, A. Sato-Otsubo, K. Terui, K. Yoshida, Y. Okuno, T. Toki, R. Wang, Y. Shiraishi, S. Miyano, I. Kato, T. Morishima, H. Fujino, K. Umeda, H. Hiramatsu, S. Adachi, E. Ito, S. Ogawa, M. Ito, T. Nakahata, and T. Heike.
- Journal Title
  
  Blo
  
  Volume : 121 Pages : 4377-4387
- DOI
  10.1182/blood-2012-12-474387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23890092, KAKENHI-PROJECT-24659496, KAKENHI-PLANNED-22134006
[Journal Article] HIV-1 Vpr Accelerates Viral Replication during Acute Infection by Exploitation of Proliferating CD4(+) T Cells In Vivo.2013
- Author(s)
  Sato K, Misawa N, Iwami S, Satou Y, Matsuoka M, Ishizaka Y, Ito M, Aihara K, An DS, and Koyanagi Y
- Journal Title
  
  PLoS Pathog
  
  Volume : 9
- DOI
  10.1371/journal.ppat.1003812
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22114003, KAKENHI-PROJECT-22220007
[Journal Article] ヒト化マウスの改良と疾患モデルへの応用2012
- Author(s)
  伊藤守
- Journal Title
  
  実験医学
  
  Volume : 30 Pages : 154-159
- Data Source
  KAKENHI-PROJECT-22220007
[Journal Article] Efficient Xenoengraftment in Severe Immunodeficient NOD/Shi-scid IL2rγnull Mice Is Attributed to a Lack of CD11c+B220+CD122+cells2012
- Author(s)
  Ito, R.
- Journal Title
  
  Journal of Immunology
  
  Volume : 189 Pages : 4313-20
- DOI
  10.4049/jimmunol.1200820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458
[Journal Article] Osteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts2012
- Author(s)
  Ito, R.
- Journal Title
  
  Experimental Hematology
  
  Volume : 40 Pages : 953-963
- DOI
  10.1016/j.exphem.2012.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458
[Journal Article] Current advances in humanized mouse models2012
- Author(s)
  Ito, R.
- Journal Title
  
  Cell Mol Immunol
  
  Volume : 9 Pages : 208-14
- DOI
  10.1038/cmi.2012.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PROJECT-22700458
[Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/ γ cnull mouse.2012
- Author(s)
  Suzuki M, Takahashi T, Katano T, Ito R, Ito M, Harigae H, Ishii N, Sugamura K.
- Journal Title
  
  Int. Immunol.
  
  Volume : 24 Pages : 243-252
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Molecular Phylogeny of the Subfamily Gerbillinae(Muridae, Rodentia)with Emphasis on Species Living in the Xinjiang-Uygur Autonomous Region of China and Based on the Mitochondrial Cytochrome b and Cytochrome c Oxidase Subunit II Genes2010
- Author(s)
  Ito, M., W.Jiang, J.J.Sato, Q.Zhen, W.Jiao, K.Goto, H.Sato, K.Ishiwata, Y.Oku, J.J.Chai, H.Kamiya
- Journal Title
  
  Zoolog Sci 27
  
  Pages : 269-278
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Molecular Phylogeny of the Subfamily Gerbillinae(Muridae, Rodentia)with Emphasis on Species Living in the Xinjiang-Uygur Autonomous Region of China and Based on the Mitochondrial Cytochrome b and Cytochrome c Oxidase Subunit II Genes2010
- Author(s)
  Ito,M.
- Journal Title
  
  Zoolog Sci 27
  
  Pages : 269-278
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.2010
- Author(s)
  Saito Y, Ishikawa F, et al
- Journal Title
  
  Nature Biotechnology 28-3
  
  Pages : 275-280
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] ヒト化マウスの現状2010
- Author(s)
  伊藤守
- Journal Title
  
  細胞工学
  
  Volume : 29 Pages : 238-242
- Data Source
  KAKENHI-PROJECT-22220007
[Journal Article] ヒト化マウスの現状と将来展望2010
- Author(s)
  伊藤守
- Journal Title
  
  MDS(Medical Science Digest)
  
  Volume : 37 Pages : 44-45
- Data Source
  KAKENHI-PROJECT-22220007
[Journal Article] ヒト化マウスの現状2010
- Author(s)
  伊藤守
- Journal Title
  
  細胞工学 29
  
  Pages : 238-242
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Regulatory T cells are necessary for implantation and maintenance of early pregnancy but not ate pregnancy in allogeneic mice.2010
- Author(s)
  Shima, T., Sasaki, Y., Itoh, M., Nakashima, A., Ishii, N., Sugamura, K. and Saito, S.
- Journal Title
  
  J. Rep. Immunol.
  
  Volume : 85 Pages : 121-129
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009
- Author(s)
  Ito R., I.Katano, K.Kawai, H.Hirata, T.Ogura, T.Kamisako, T.Eto, M.Ito
- Journal Title
  
  Transplantation 87
  
  Pages : 1654-1658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice2009
- Author(s)
  Ito, R., I. Katano, K. Kawai, H. Hirata, T. Ogura, T. Kamisako, T. Eto, and M. Ito.
- Journal Title
  
  Transplantation 87
  
  Pages : 1654-1658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Selective infection of CD4+ effector memory T lymphocytes leads to preferential depletion of memory T lymphocytes in R5 HIV-1-infected humanized NOD/SCID/IL-2Rgammanull mice.2009
- Author(s)
  Nie C., K.Sato, N.Misawa, H.Kitayama, H.Fujino, H.Hiramatsu, T.Heike, T.Nakahata, Y.Tanaka, M.Ito, Y.Koyanagi
- Journal Title
  
  Virology 394
  
  Pages : 64-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice).2009
- Author(s)
  Watanabe Y, Takahashi T, Ito M, Sugamura K, et al
- Journal Title
  
  Int. Immunol. 21
  
  Pages : 843-858
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009
- Author(s)
  Ito R, Ito M, et al
- Journal Title
  
  Transplantation 87
  
  Pages : 1654-1658
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009
- Author(s)
  Ito R, Katano I, Kawai K, Hirata H, 0gura T, Kamisako T, Eto T, and Ito M.
- Journal Title
  
  Transplantaion
  
  Volume : 87 Pages : 1654-1658
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull(NOG) mice (hu-HSC NOG mice).2009
- Author(s)
  Watanabe Y, Takahashi T, 0kajima A, Shiokawa M, Ishii N, Katano I,Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S and Sugamura K.
- Journal Title
  
  Int. Immunol.
  
  Volume : 21 Pages : 843-858
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] NOGマウスとヒト化マウス2009
- Author(s)
  伊藤守
- Journal Title
  
  ファルマシア 45
  
  Pages : 1077-1081
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull (NOG) mice (hu-HSC NOG mice).2009
- Author(s)
  Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, Sugamura K
- Journal Title
  
  Int Immunol
  
  Volume : 21 Pages : 843-858
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Highly sensitive model for xenogenic GVHD using severe immunodeficient NOG mice.2009
- Author(s)
  Ito R, Katano I, Kawai K, Hirata H, Ogura T, Kamisako T, Eto T, Ito M.
- Journal Title
  
  Transplantation
  
  Volume : 87 Pages : 1654-1658
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.2009
- Author(s)
  Ito M, Kobayashi K, Nakahata T.
- Journal Title
  
  Curr Top Microbiol Immunol
  
  Volume : 324 Pages : 53-76
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Highly sensitive model for xenogenic-GVHD using severe immunodeficient NOG mice2009
- Author(s)
  Ito, R.
- Journal Title
  
  Transplantation 87(印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Interferon-alpha 2b-induced thrombocytopenia is caused by inhibition of platelet production but not proliferation and endomitosis in human megakaryocytes.2008
- Author(s)
  Yamane A., T.Nakamura H.Suzuki M.Ito, Y.Ohnishi, Y.Ikeda, Y.Miyakawa
- Journal Title
  
  Blood 112
  
  Pages : 542-550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] A new humanized mouse model of Epstein-Barr virus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses.2008
- Author(s)
  Yajima M., K.Imadome, A.Nakagawa, S.Watanabe, K.Terashima, H.Nakamura, M.Ito, N.Shimizu, M.Honda, N.Yamamoto, S.Fujiwara
- Journal Title
  
  J Infect Dis 198
  
  Pages : 673-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] NOD/Shi IL2rg<null>(NOG) mice appropriate for humanized mouse models.2008
- Author(s)
  Ito M, Kobayashi K, Nakahata T
- Journal Title
  
  "Humanized mice" , Nomura T, et al.(eds.), Current Topics in Microbiol. and Immunol., Springer-Verlag Berlin Heidelberg
  
  Volume : 324 Pages : 53-76
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Interleukin-4-transgenic hu-PBL-SCID mice: A model for the screening of antiviral drugs and immunotherapeutic agents against X4 HIV-1 viruses.2008
- Author(s)
  Okuma K, Tanaka r, Ogura T, Ito M, Kumakura S, Yanaka M, Nishizawa M, Sugiura W, Yamamoto N, Tanaka Y
- Journal Title
  
  J. Infect. Dis.
  
  Volume : 197 Pages : 134-141
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] The origins of blood: induction of hematopoietic stem cells from different sources.2008
- Author(s)
  Saito Y and Ishikawa F.
- Journal Title
  
  Cell Stem Cell
  
  Volume : 3 Pages : 8-10
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.2008
- Author(s)
  Ito M, Kobayashi K, Nakahata T
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages : 53-76
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Quiescent human hematopoietic stem cells in the bone marrow niches organize the hierarchical structure of hematopoiesis.2008
- Author(s)
  Yahata T., Y.Muguruma, S.Yumino, Y.Sheng, T.Uno, H.Matsuzawa, M.Ito, S.Kato, T.Hotta, K.Ando
- Journal Title
  
  Stem Cells 26
  
  Pages : 3228-3236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Development of human Graafian follicles following transplantation of human ovarian tissue into NOD/SCID/gammacnull mice.2008
- Author(s)
  Terada Y., Y.Terunuma-Sato, T.Kakoi-Yoshimoto, H.Hasegawa, T.Ugajin, Y.Koyanagi, M.Ito, T.Murakami, H.Sasano, N.Yaegashi, K.Okamura
- Journal Title
  
  Am J Reprod Immunol 60
  
  Pages : 534-540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Quiescent human hematopoietic stem cells in the bone marrow niches organize the hierarchical structure of hematopoiesis2008
- Author(s)
  T., Y. Muguruma, S. Yumino, Y. Sheng, T. Uno, H. Matsuzawa, M. Ito, S. Kato, T. Hotta, and K. Ando.
- Journal Title
  
  Stem Cells 26
  
  Pages : 3228-3236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Quiescent human hematopoietic stem cells in the bone marrow niches organize the hierarchical structure of hematopoiesis.2008
- Author(s)
  Yahata, T, Muguruma Y, Yumino S, Sheng Y, Uno T, Matsuzawa H, Ito M, Kato S, Hotta T, and Ando K.
- Journal Title
  
  Stem Cells
  
  Volume : 26 Pages : 3228-3236
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] NOD/Shi-scid IL2rgamma(null)(NOG) mice more appropriate for humanized mouse models.2008
- Author(s)
  Ito M, Kobayashi K and Nakahata T.
- Journal Title
  
  Curr. Top. Microbiol. Immunol.
  
  Volume : 324 Pages : 53-76
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Establishing EGFP congenic mice in a NOD/Shi-scid IL2Rg(null) (NOG) genetic background using a marker-assisted selection protocol (MASP).2008
- Author(s)
  Suemizu H., C.Yagihashi, T.Mizushima, T.Ogura, T.Etoh, K.Kawai, M.Ito
- Journal Title
  
  Exp Anim 57
  
  Pages : 471-477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.2008
- Author(s)
  Ito M., K.Kobayashi, T.Nakahata
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages : 53-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in the NOD-SCTD/IL2rg^<null> mice.2008
- Author(s)
  Ishikawa F, Saito Y, Yoshida S, Harada M, Shultz LD.
- Journal Title
  
  Curr TopMicrobiol Immunol
  
  Volume : 324 Pages : 87-94
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice.2008
- Author(s)
  Suemizu H., M.Hasegawa, K.Kawai, K.Taniguchi, M.Monnai, M.Wakui, M.Suematsu, M.Ito, G.Peltz, M.Nakamura
- Journal Title
  
  Biochem Biophys Res Commun 377
  
  Pages : 248-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Antigen-specific antibody production of human B cells in NOG mice reconstituted with the human immune system.2008
- Author(s)
  Ito R., M.Shiina, Y.Saito, Y.Tokuda, Y.Kametani, S.Habu
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages : 95-107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] 特集:動物とヒトの比較腫瘍学、異種移植系の宿主側の検討2008
- Author(s)
  伊藤守
- Journal Title
  
  アニテックス 19
  
  Pages : 13-19
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Humanized mice for human retrovirus infection.2008
- Author(s)
  Koyanagi Y., Y.Tanaka, M.Ito, N.Yamamoto
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages : 133-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] NOD/Shi-scid IL2rgamma (null) (NOG) micemore appropriate for humanized mouse models2008
- Author(s)
  Ito, M., K. Kobayashi, and T. Nakahata.
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages : 53-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] A new humanized mouse model of Epstein-Barrvirus infection that reproduces persistent infection, lymphoproliferative disorder, and cell-mediated and humoral immune responses2008
- Author(s)
  Yajima, M., K. Imadome, A. Nakagawa, S. Watanabe, K. Terashima, H. Nakamura, M. Ito, N. Shimizu, M. Honda, N. Yamamoto, and S. Fujiwara.
- Journal Title
  
  J Infect Dis 198
  
  Pages : 673-682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice2008
- Author(s)
  Suemizu, H., M. Hasegawa, K. Kawai, K. Taniguchi, M. Monnai, M. Wakui, M. Suematsu, M. Ito, G. Peltz, and M. Nakamura.
- Journal Title
  
  Biochem Biophys Res Commun 377
  
  Pages : 248-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models2008
- Author(s)
  Ito, M.
- Journal Title
  
  Curr Top Microbiol Immunol 324
  
  Pages : 53-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/gammacnull(NOG) mice.2007
- Author(s)
  Suemizu H, Monnai M, 0hnishi Y, Ito M, Tamaoki N, Nakamura M
- Journal Title
  
  Int. J. Oncol.
  
  Volume : 31 Pages : 741-751
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice.2007
- Author(s)
  Ninomiya M, Abe A, Katsumi A, Xu J, Ito M, Arai F, Suda T, Ito M, Kiyoi H, Kinoshita T, Naoe T
- Journal Title
  
  Leukemia
  
  Volume : 21 Pages : 136-142
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.2007
- Author(s)
  Ishikawa F, Niiro H, Iino T, Yoshida S, Saito N, 0nohara S, Miyamoto T, Minagawa H, Fujii SI, Shultz LD, Harada M, Akashi K.
- Journal Title
  
  Blood
  
  Volume : 119 Pages : 3591-3660
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Chemotherapy-resistant human AML stem cells home to and engraft within the bone marrow endsteal region.2007
- Author(s)
  Ishikawa F, Yoshida S, Saito Y, Hijikata A, Kitamura H, Tanaka S, Nakamura R, Tanaka T, Tomiyama H, Saito N, Fukata M, Miyamoto T, Lyons B, 0hshima K, Uchida N, Taniguchi S, 0hara 0, Akashi K, Harada M, Shultz LD.
- Journal Title
  
  Nature Biotechnol
  
  Volume : 25 Pages : 1315-1321
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCTD/gamma(c)null mice through cell fusion.2007
- Author(s)
  Fujino H, Hiramatsu H, Tsuchiya A, Niwa A, Noma H, Shiota M, Umeda K, Yoshimoto M, Ito M, Heike T, Nakahata T
- Journal Title
  
  Faseb J.
  
  Volume : 21 Pages : 3499-3510
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Noninvasive and real-time assessment of reconstructed functional human endortrium in NOD/SCID/{gamma}formula immunodeficient mice.2007
- Author(s)
  Masuda H, Maruyama T, Hiratsu E, Yamane J, Iwanami A, Nagashima T, 0no M, Miyoshi H, 0kano HJ, Ito M, Tamaoki N, Nomura T, 0kano H, Matsuzaki Y, Yoshimura Y
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume : 104 Pages : 1925-1930
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.2007
- Author(s)
  Watanabe S, Terashima K, 0hta S, Horibata S, Yajima M, Shiozawa Y, Dewan MZ, Yu Z, Ito M, Morio T, Shimizu N, Honda M, Yamamoto N
- Journal Title
  
  Blood
  
  Volume : 109 Pages : 212-218
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Humanized NOD/SCTD/IL2R{gamma}null mice transplanted with hematopoietic stem cells under non-myeloablative condition show prolonged lifespans and allow detailed analysis of HIV-1 pathogenesis.2007
- Author(s)
  Watanabe S, 0hta S, Yajima M, Terashima K, Ito M, Mugishima H, Fujiwara S, Shimizu K, Honda M, Shimizu N, Yamamoto N
- Journal Title
  
  J. Virol.
- Data Source
  KAKENHI-PLANNED-19059001
[Journal Article] Identification of a key molecular regulator of liver metastasis in human pancreatic carcinoma using a novel quantitative model of metastasis in NOD/SCID/gammacnull (NOG) mice.2007
- Author(s)
  Suemizu H., M.Monnai, Y.Ohnishi, M.Ito, N.Tamaoki, M.Nakamura
- Journal Title
  
  Int J Oncol 31
  
  Pages : 741-751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion.2007
- Author(s)
  Fujino H., H.Hiramatsu, A.Tsuchiya, A.Niwa, H.Noma, M.Shiota, K.Umeda, M.Yoshimoto, M.Ito, T.Heike, T.Nakahata
- Journal Title
  
  Faseb J 21
  
  Pages : 3499-3510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.2007
- Author(s)
  Watanabe S., K.Terashima, S.Ohta, S.Horibata, M.Yajima, Y.Shiozawa, M.Z.Dewan, Z.Yu, M.Ito, T.Morio, N.Shimizu, M.Honda, N.Yamamoto
- Journal Title
  
  Blood 109
  
  Pages : 212-218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] A novel nonpeptidyl human c-Mpl activator stimulates human megakaryopoiesis and thrombopoiesis.2006
- Author(s)
  Nakamura T., Y.Miyakawa, A.Miyamura, A.Yamane, H.Suzuki, M.Ito, Y.Ohnishi, N.Ishiwata, Y.Ikeda, N.Tsuruzoe
- Journal Title
  
  Blood 107
  
  Pages : 4300-4307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Reconstitution of the functional human hematopoietic microenvironment derived from human mesenchymal stem cells in the murine bone marrow compartment.2006
- Author(s)
  Muguruma Y., T.Yahata, H.Miyatake, T.Sato, T.Uno, J.Itoh, S.Kato, M.Ito, T.Hotta, K.Ando
- Journal Title
  
  Blood 107
  
  Pages : 1878-1887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Development of human-human hybridoma from anti-Her-2 peptide-producing B cells in immunized NOG mouse.2006
- Author(s)
  Kametani Y., M.Shiina, I.Katano, R.Ito, K.Ando, K.Toyama, H.Tsukamoto, T.Matsumura, Y.Saito, D.Ishikawa, T.Taki, M.Ito, K.Imai, Y.Tokuda, S.Kato, N.Tamaoki, S.Habu
- Journal Title
  
  Exp Hematol 34
  
  Pages : 1239-1247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Clonal analysis of thymus-repopulating cells presents direct evidence for self-renewal division of human hematopoietic stem cells.2006
- Author(s)
  Yahata T., S.Yumino, Y.Seng, H.Miyatake, T.Uno, Y.Muguruma, M.Ito, H.Miyoshi, S.Kato, T.Hotta, K.Ando
- Journal Title
  
  Blood 108
  
  Pages : 2446-2454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18100005
[Journal Article] Hodgkin's lymphoma cells are efficiently engrafted and tumor marker CD30 is expressed with constitutive nuclear factor-kappaB activity in unconditioned NOD/SCID/gammac(null)mice2005
- Author(s)
  Dewan, M.Z., M.Watanabe, S.Ahmed, K.Terashima, S.Horiuchi, T.Sata, M.Honda, M.Ito, T.Watanabe, R.Horie, N.Yamamoto
- Journal Title
  
  Cancer Sci 96
  
  Pages : 466-473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Reproduction of menstrual changes in transplanted human endometrial tissue in immunodeficient mice2005
- Author(s)
  Matsuura-Sawada, R., T.Murakami, Y.Ozawa, H.Nabeshima, J.Akahira, Y.Sato, Y.Koyanagi, M.Ito, Y.Terada, K.Okamura
- Journal Title
  
  Hum Reprod 20
  
  Pages : 1477-1484
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Characterization of SSU and LSU rRNA genes of three Trypanosoma(Herpetosoma)grosi isolates maintained in Mongolian jirds2005
- Author(s)
  Sato, H., A.Osanai, H.Kamiya, Y.Obara, W.Jiang, Q.Zhen, J.Chai, Y.Une, M.Ito
- Journal Title
  
  Parasitology 130
  
  Pages : 157-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Independent accumulations of tau and amyloid β-protein in the human entorhinal cortex.2005
- Author(s)
  Katsuno T, Morishima-Kawashima M, Saito Y, Yamanouchi H, Ishiura S, Murayama S, Ihara Y
- Journal Title
  
  Neurology 64
  
  Pages : 687-692
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Visualization of newly deposited tau in neurofibrillary tangles and neuropil threads.2005
- Author(s)
  Miyasaka T, Watanabe A, Saito Y, Murayama S, Mann DMA, Yamazaki M, Ravid R, Morishima-Kawashima M, Nagashima K, Ihara Y
- Journal Title
  
  J Neuropathol Exp Neurol 64
  
  Pages : 665-674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Establishment of a new model of human multiple myeloma using NOD/SCID/gammac(null)(NOG)mice2004
- Author(s)
  Miyakawa, Y., Y.Ohnishi, M.Tomisawa, M.Monnai, K.Kohmura, Y.Ueyama, M.Ito, Y.Ikeda, M.Kizaki, M.Nakamura
- Journal Title
  
  Biochem Biophys Res Commun 313
  
  Pages : 258-262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Competitive repopulation assay of two gene-marked cord blood units in NOD/SCID/gammac(null)mice2004
- Author(s)
  Yahata, T., K.Ando, H.Miyatake, T.Uno, T.Sato, M.Ito, S.Kato, T.Hotta.
- Journal Title
  
  Mol Ther 10
  
  Pages : 882-891
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] T cell-dependent elimination of dividing Trypanosoma grosi from the bloodstream of Mongolian jirds2004
- Author(s)
  Sato, H., K.Ishita, A.Osanai, M.Yagisawa, H.Kamiya, M.Ito
- Journal Title
  
  Parasitology 128
  
  Pages : 295-304
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Epidemiology of Helicobacter infection in wild rodents in the Xinjiang-Uygur autonomous region of China2004
- Author(s)
  Goto, K., W.Jiang, Q.Zheng, Y.Oku, H.Kamiya, T.Itoh, M.Ito
- Journal Title
  
  Curr Microbiol 49
  
  Pages : 221-223
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Prompt tumor formation and maintenance of constitutive NF-kappaB activity of multiple myeloma cells in NOD/SCID/gammacnull mice2004
- Author(s)
  Dewan, M.Z., M.Watanabe, K.Terashima, M.Aoki, T.Sata, M.Honda, M.Ito, S.Yamaoka, T.Watanabe, R.Horie, N.Yamamoto
- Journal Title
  
  Cancer Sci 95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body2004
- Author(s)
  Kambe, N., H.Hiramatsu, M.Shimonaka, H.Fujino, R.Nishikomori, T.Heike, M.Ito, K.Kobayashi, Y.Ueyama, N.Matsuyoshi, Y.Miyachi, T.Nakahata
- Journal Title
  
  Blood 103
  
  Pages : 860-867
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Gem GTPase and tau : morphological changes induced by Gem GTPase in CHO cells are antagonized by tau.2004
- Author(s)
  Oyama F, Kotliarova S, Harada A, Ito M, Miyazaki H, Ueyama Y, Hirokawa N, Nukina N, Ihara Y
- Journal Title
  
  J Biol Chem 279
  
  Pages : 27272-27277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Persistent infection of Mongolian jirds with a non-pathogenic trypanosome, Trypanosoma(Herpetosoma)grosi2003
- Author(s)
  Sato, H., K.Ishita, K.Matsuo, T.Inaba, H.Kamiya, M.Ito
- Journal Title
  
  Parasitology 127
  
  Pages : 357-363
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Fate of neural stem cells grafted into injured inner ears of mice2003
- Author(s)
  Tateya, I., T.Nakagawa, F.Iguchi, T.S., Kim, T.Endo, S.Yamada, R.Kageyama, Y.Naito, J.Ito.
- Journal Title
  
  Neuroreport 14
  
  Pages : 1677-1681
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Rapid tumor formation of human T-cell leukemia virus type 1-infected cell lines in novel NOD-SCID/gammac(null)mice : suppression by an inhibitor against NF-kappaB2003
- Author(s)
  Dewan, M.Z., K.Terashima, M.Taruishi, H.Hasegawa, M.Ito, Y.Tanaka, N.Mori, T.Sata, Y.Koyanagi, M.Maeda, Y.Kubuki, A.Okayama, M.Fujii, N.Yamamoto
- Journal Title
  
  J Virol 77
  
  Pages : 5286-5294
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Complete reconstitution of Human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model2003
- Author(s)
  Hiramatsu, H., R.Nishikomori, T.Heike, M.Ito, K.Kobayashi, K.Katamura, T.Nakahata
- Journal Title
  
  Blood 102
  
  Pages : 873-880
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null)(NOG)mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells2003
- Author(s)
  Matsumura, T., Y.Kametani, K.Ando, Y.Hirano, I.Katano, R.Ito, M.Shiina, H.Tsukamoto, Y.Saito, Y.Tokuda, S.Kato, M.Ito, K.Motoyoshi, S.Habu.
- Journal Title
  
  Exp Hematol 31
  
  Pages : 789-797
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Disruption of imprinting in cloned mouse fetuses from embryonic stem cells2003
- Author(s)
  Ogawa, H., Y.Ono, N.Shimozawa, Y.Sotomaru, Y.Katsuzawa, H.Hiura, M.Ito, T.Kono.
- Journal Title
  
  Reproduction 126
  
  Pages : 549-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Journal Article] Meriones meridianus and Lagurus lagurus as alternative definitive hosts of Echinococcus multilocularis and E.granulosus2002
- Author(s)
  Oku, Y., J.Wei, J.J.Chai, I.Osman, L.F.Liao, M.Asakawa, K.Hagiwara, K.Kobayashi, M.Ito
- Journal Title
  
  Exp Anim 51
  
  Pages : 27-32
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Seroprevalence of Borna disease virus in domestic animals in Xinjiang, China2001
- Author(s)
  Hagiwara, K., M.Asakawa, L.Liao, W.Jiang, S.Yan, J.Chai, Y.Oku, K.Ikuta, M.Ito
- Journal Title
  
  Vet Microbiol 80
  
  Pages : 383-389
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Journal Article] Mutant-presenilin 2-transgenic mice : A large increase in the levels of Aβ42 is presumably associated with the low-density membrane domain that contains decreased levels of glycerophospholipids and sphingomyelin.2000
- Author(s)
  Sawamura N, Morishima-Kawashima M, Waki H, Kobayashi K, Kuramochi T, Ito M, Oyama F, Ando S, Ihara Y
- Journal Title
  
  J Biol Chem 275
  
  Pages : 27901-27908
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210005
[Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse
- Author(s)
  Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K
- Journal Title
  
  Int.Immunol.
  
  Volume : (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059001
[Presentation] Functional NK cells developed from human hematopoietic stem cell in human interleukin-2 transgenic NOG mice.2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  第15回国際免疫学会
- Place of Presentation
  ミラノ・イタリア
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013
- Author(s)
  Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  第15回国際免疫学会
- Place of Presentation
  ミラノ・イタリア
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] IgE-mediated allergic responses in human mast cells in humanized NOG mice expressing human IL-3 and GM-CSF.2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Satoshi Nunomura, Chisei Ra, Akio Mori, Sadakazu Aiso, Mamoru Ito
- Organizer
  第15回国際免疫学会
- Place of Presentation
  ミラノ・イタリア
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Predominant development of mature and functional human NK Cells in a novel human IL-2 producing transgenic NOD-scid,IL-2Rg KO (NOG) mouse.2013
- Author(s)
  Ikumi Katano, Ryoji Ito, Takeshi Takahashi, Mamoru Ito
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Retrogenic expression of human TCR in HLA-DR4 trasngenic NOG mice.2013
- Author(s)
  Takeshi Takahashi, Ikumi Katano, Ryoji Ito, Mamoru Ito
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Severely Immunodeficient Mice Improved in CIEA for Humanized Mouse Models.2013
- Author(s)
  Ito, M.
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Invited
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Human mast cell mediated allergic responses in humanized NOG mouse expressing human IL-3 and GM-CSF.2013
- Author(s)
  Ryoji Ito, Takeshi Takahashi, Ikumi Katano, Kenji Kawai, Mamoru Ito
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Dose Dependent Effects of Human IL-2 on the reconstitution and Function of Human Regulatory T cells in Humanized Mice.2013
- Author(s)
  Li, Y., Katano, I., Dusseaux, M., Pang, Y., Court, N. Rogge, L., Ito, M., Strick-Marchand, H. and Di Santo, J.
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Assessment of the Pathogenic Potential of Simian Retrovirus Type 4 in Humanized Mice.2013
- Author(s)
  Kobayashi, T., Sato, K., Misawa, N., Yoshikawa, R., Takeuchi, J., Kanemura, Y., Fukuhara, M., Okamoto, M., Miyazawa, T., Yasunaga, J., Matsuoka, M., Aihara, K., An, D.S., Ito, M. and Koyanagi, Y.
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Characterization of human Eosinophil in HSC-transferred NOG-human IL-5 transgenic mice2013
- Author(s)
  片野いくみ, 伊藤亮治, 高橋武司, 伊藤守
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Antibody-Secreting B Cells are Directly Developed from Transitional B cells of Humanized NOG Mice.2013
- Author(s)
  Kametani, Y., Mori, S., Shimada, S., Oshima, S., Aokawa, J., Okada, Y., Goto, Y., Tsuda, B., Yahata, T., Ito, R., Katano, I., Suemizu, H., Ito, M., Habu, S. and Ando, K.
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Restriction and Diversification of HIV-1 Mediated by APOBEC3-Induced G-to-A Mutation in Humanized Mouse Model. 4th International Workshop of Humanized Mice.2013
- Author(s)
  Sato, K., Takeuchi, J., Misawa, N., Izumi, T., Kobayashi, T., Kimuram Y., Iwami, S., Takaori-Kondo, A., Hu, W-S., Aihara, K., Ito, M., An, D.S., Pathakm, V. and Koyanagi, Y.
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Leukemic Modeling in Humanized Mice. 4th International Workshop of Humanized Mice.2013
- Author(s)
  Kato, I., Morita, M., Nishinaka, Y., Hashimoto, Y., Amano, N., Watanabe, A., Saida, S., Niwa, A., Saito, M., Umeda, K., Hiramatsu, H., Watanabe, K-I., Ito, M., Adachi, S., Heike, T. and Nakahata, T.
- Organizer
  第4回国際ヒト化マウスワークショップ
- Place of Presentation
  ソウル
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスを用いたヒトアレルギーモデルの開発2013
- Author(s)
  伊藤亮治
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  茨城・筑波国際会議場
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Retrogenic expression of human TCR in HLA-DR4 transgenic NOG mice2013
- Author(s)
  高橋武司, 片野いくみ, 伊藤亮治, 伊藤守
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Pathology of cutaneous xeno-GVHD in human CD4 T cell transplanted NOG mice.2013
- Author(s)
  伊藤亮治, 片野いくみ, 高橋武司, 伊藤守
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  千葉・幕張メッセ
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Development of humanized mice model2012
- Author(s)
  Mamoru Ito
- Organizer
  1st Samsung Humanized Mice Workshop
- Place of Presentation
  Soul
- Invited
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Immunodeficient mice and humanized mouse models2012
- Author(s)
  Mamoru Ito
- Organizer
  The 2012 Spring conference of the Korea Association of Immunologist
- Place of Presentation
  Soul
- Invited
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスにおけるヒトミエロイド系細胞の分化亢進2012
- Author(s)
  伊藤亮治
- Organizer
  第59回日本実験動物学会総会
- Place of Presentation
  別府
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒトIL-3/GM-CSFトランスジェニックNOGマウスを用いたヒトアレルギーモデルの確立2012
- Author(s)
  伊藤亮治
- Organizer
  第62回日本アレルギー学会秋季学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Functional maturation of human myeloid cells in NOG transgenic humanized mouse strain expressing human IL-3 and GM-CSF2012
- Author(s)
  Ito R.
- Organizer
  第41回日本免疫学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒト化マウスーその限界と今後の展望2011
- Author(s)
  伊藤守
- Organizer
  第58回実験動物学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Development of NOG mouse based immunodeficient mice in CIEA2011
- Author(s)
  Ito, M.
- Organizer
  3^<rd> International Workshop of Humanized Mice
- Place of Presentation
  Pittsburgh, USA
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] 異種移植研究への応用に期待がかかるヒト化動物モデルの開発2011
- Author(s)
  伊藤守
- Organizer
  第14回日本異種移植研究会
- Place of Presentation
  広島
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] A novel humanized mouse model : improvement of human myelopoiesisin IL-3/GM-CSF transgenic NOG mice reconstituted with human hematopoietic stem cells2011
- Author(s)
  伊藤亮治
- Organizer
  第40回日本免疫学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] NOGマウスを用いたxeno-GVHD抑制機構の解明2010
- Author(s)
  伊藤亮治
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] The analysis of the functions of human T cells in humanized NOD/shi-scid/gamma c^<null> (NOG)-HLA transgenic mice.2010
- Author(s)
  Takahashi T, Suzuki M, Katano I, Ito R, Ishii N, Ito M, Sugamura K.
- Organizer
  国際免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-19059001
[Presentation] Xeno-GVHD occurred in NOG mice after transfer of CD4 and CD8 T cells human PBMC.2010
- Author(s)
  Ito, R
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Super immunodeficient NOG mice for generating humanized mice.2010
- Author(s)
  Ito, M.
- Organizer
  KALAS International Symposium
- Place of Presentation
  Busan, Korea
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Interferon-gamma produced by IKDC has a crucial role in suppression of xeno-GVHD in NOG mice.2010
- Author(s)
  Ito, R
- Organizer
  11th International Symposium on Dendritic Cells
- Place of Presentation
  Lugano, Switzerland
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Mouse models as "humanized mice"2009
- Author(s)
  Ito M.
- Organizer
  2^<nd> IWHM
- Place of Presentation
  Holland
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] High sensitivity to xeno-GVHD in severely immunodeficient NOG mice attributable to dysfunction of dendritic cells.2009
- Author(s)
  Ito R, Ito M, et al
- Organizer
  第2回ヒト化マウス国際ワークショップ
- Place of Presentation
  オランダ
- Data Source
  KAKENHI-PLANNED-19059001
[Presentation] The analysis of the functions of human B and T cells in humanized NOD/shi/γcnull (NOG) mice (hu-HSC NOG mice).2009
- Author(s)
  Takahashi T, Ito M, Sugamura K, et al
- Organizer
  第2回ヒト化マウス国際ワークショップ
- Place of Presentation
  オランダ
- Data Source
  KAKENHI-PLANNED-19059001
[Presentation] 「ヒト血液幹細胞移植マウスのウイルス病原性解析への利用」シンポジウム「ヒト化動物の現状と今後」2009
- Author(s)
  小柳義夫、佐藤佳、伊藤守
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] High sensitivity to xeno-GVHD in severely immunodeficient NOG mice attributable to dysfunction of dendritic cells2009
- Author(s)
  Ito R
- Organizer
  2^<nd> IWHM
- Place of Presentation
  Holland
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] Mouse models as "humanized mice"2009
- Author(s)
  Ito M.
- Organizer
  2^<nd> IWHM
- Place of Presentation
  Holland
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] IFNg producing killer dendritic cells have a suppressive effect on Xeno-GVHD in NOG mice2009
- Author(s)
  Ito, R.
- Organizer
  第39日本免疫学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] The analysis of the functions of human B and T cells in humanized NOD/shi/γcnull (NOG) mice (hu-HSC NOG mice)2009
- Author(s)
  Takahashi T, Watanabe Y, Okajima A, Katano I, Ito R, Ito M, Ishii N, Tsuchiya S, Sugamura K
- Organizer
  2nd international workshop on humanized mice
- Place of Presentation
  オランダ・アムステルダム
- Data Source
  KAKENHI-PLANNED-19059001
[Presentation] Mouse models as "humanized mice"2009
- Author(s)
  Ito M.
- Organizer
  2^<nd> International workshop of humanized mice
- Place of Presentation
  Holland
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] Dendritic cells have a suppressive effect on xeno-GVHD in novel immunodeficient NOG mice2008
- Author(s)
  伊藤亮治
- Organizer
  第10回国際樹状細胞シンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] NOGマウスにおける樹状細胞の機能低下は高度Xeno-GVHD発症の要因となる2008
- Author(s)
  伊藤亮治
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] ヒトDelta-like 1トランスジェニックNOGマウスに発症する骨硬化はヒト造血系の再構築を抑制する2008
- Author(s)
  伊藤亮治
- Organizer
  第26回骨代謝学会
- Place of Presentation
  大坂
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] Dendritic cells have a suppressive effect on xeno-GVHD in novel immunodeficient NOG mice2008
- Author(s)
  伊藤亮治、片野いくみ、小倉智幸、川井健司、伊藤守
- Organizer
  第10回国際樹状細胞シンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] C-kit変異をもつ重度免疫不全NOG-Wvマウスはヒト細胞の高い生着性を示す2008
- Author(s)
  片野いくみ、伊藤亮治、川井健司、伊藤守
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] ヒト Delta-like 1トランスジェニックNOGマウスに発症する骨硬化はヒト造血系の再構築を抑制する2008
- Author(s)
  伊藤亮治
- Organizer
  第26回骨代謝学会
- Place of Presentation
  大坂
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] Dendritic cells have a suppressive effect on xeno-GVHD in novel immunodeficient NOG mice2008
- Author(s)
  伊藤亮治
- Organizer
  第10回国際樹状細胞シンポジウム
- Place of Presentation
  神戸
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] NOGマウスにおける樹状細胞の機能低下は高度 Xeno-GVHD発症の要因となる2008
- Author(s)
  伊藤亮治
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] 重度免疫不全NOGマウスを用いた高GVHD感受性モデル2008
- Author(s)
  伊藤亮治
- Organizer
  日本実験動物科学技術2008
- Place of Presentation
  仙台
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-18100005
[Presentation] Development of NOD/SCID/gcnull(NOG)mice and their application on in vivo medicine2004
- Author(s)
  Mamoru Ito
- Organizer
  The 37^<th> Annual Meeting of the Japanese Association of Germfree Life and Gnotobiology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Presentation] Charateristics of NOG mice and their application to degenerative medicine2004
- Author(s)
  Mamoru Ito
- Organizer
  Keio University, COE synpodium
- Place of Presentation
  Tokyo
- Year and Date
  2004-03-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Presentation] NOGマウスの特性と再生治療研究への応用2004
- Author(s)
  伊藤守
- Organizer
  慶應大学COE再生公開シンポジウム
- Place of Presentation
  東京
- Year and Date
  2004-03-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Presentation] 複合免疫不全NOD/SCIFD/gcnull(NOG)マウスの開発とそのIn vivo実験医学への応用2004
- Author(s)
  伊藤守
- Organizer
  第37回日本無菌生物ノトバイオロジー学会
- Place of Presentation
  横浜
- Year and Date
  2004-01-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15300147
[Presentation] epidemiology of Hilicobacter Infection in Wild Rodents in the Xinjinag-Uygur Autonomous region of China2003
- Author(s)
  Kazuo Goto, W.Jiang, Q.Zheng, Y.Oku, H.Kamiya, T.Itch, M.Ito
- Organizer
  XVIth International workshop gastrointestinal pathology and Helicobacter
- Place of Presentation
  European Helicobacter study group
- Year and Date
  2003-09-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13575039
[Presentation] 重度免疫不全NOGヘアレスマウスの計画生産および特性データ
- Author(s)
  何裕遥、小倉智幸、水澤卓馬、上迫努、高橋利一、伊東一昭、堤秀樹、江藤智生、伊藤守、日置恭司
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] TK-NOGマウスの計画生産および特性データ
- Author(s)
  富山香代、小倉智幸、何裕遥、上迫努、高橋利一、伊藤守、日置恭司、末水洋志
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒトIL=5遺伝子導入型NOGマウスのヒト好酸球分化能の解析
- Author(s)
  片野いくみ、高橋武司、伊藤亮治、上迫努、何裕遥、小倉智幸、高橋利一、末水洋志、河上裕、伊藤守
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] APOBEC3F potently promotes HIV-1 diversification and evolution in humanized mouse model.
- Author(s)
  Sato, K., Shibata, J., Izumi, T., Misawa, N., Kobayashi, T., Kimura, Y., Ito, M., Pathak, V. K., Koyanagi, Y.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Retroviruses
- Place of Presentation
  New York, USA
- Year and Date
  2014-05-19 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] BRGヌードマウスの計画生産および特性データ
- Author(s)
  水澤卓馬、小倉智幸、何裕遥、上迫努、高橋利一、江藤智生、伊藤守、日置恭司
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] Analysis of the human immunological system reconstructed in the hIL4-Tg NOG mouse.
- Author(s)
  Kikuchi Y., Miyamoto A., Tsuda B., Katano I., Tokuda Y., Ito M., Kametani Y.
- Organizer
  第43回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] NOGマウス環境下で分化するtransitional B細胞の抗体産生細胞の解析
- Author(s)
  小島美香、森修弥、嶋田新、大島志乃、伊藤守、鈴木隆二、安藤潔、亀谷美恵
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-22220007
[Presentation] ヒト免疫系再構築マウスTransitional B細胞の抗体産生能解析
- Author(s)
  4.小島美香、森修弥、大島志乃、伊藤守、安藤潔、亀谷美恵
- Organizer
  第61回日本実験動物学会総会
- Place of Presentation
  札幌
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-22220007

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# of Collaborated Projects : 1results

# of Collaborated Products : 2results
87. 岡澤均 (50261996)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
88. KATANO Ikumi

# of Collaborated Projects : 1results

# of Collaborated Products : 18results
89. TAMAKI Tohru

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
90. YOKOIYAMA Shigeyuki

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
91. BAO Siimin

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
92. ISHII Hajime

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
93. 赤松健一

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
94. TANG Linーhua

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
95. QU JingーQi

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
96. GUAN LiーRen

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
97. HASAN S.Z.Ak

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
98. M.ALI Ozcel

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
99. CHANG Kwang

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
100. WANG Xiaoyan

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
101. ウイホンキエン

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
102. OTSU Makoto

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
103. ITO ETSURO

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
104. TOKI Tsutomu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
105. SATO Aiko

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
106. NAKAYAMA-MUGURUMA YUKARI

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
107. 河上裕

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
108. 中内啓光

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
109. 江藤浩之

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
110. 松下弘道

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
111. 松岡雅雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
112. 外丸佑介

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

ITO Mamoru 伊藤 守

Research Projects

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Approaches to standardization of humanized mice by transplanting human hematopoietic stem cells (HSC) and thymus generated from induced pluripotent stem (iPS) cells.Principal InvestigatorOngoing

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Development of experimentation systems related to personalized medicine using humanized NOG micePrincipal Investigator

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Basic study to establish "humanized animal model" by improvement and modification of severely immunodeficient NOG mousePrincipal Investigator

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Basic studies on animal model for regenerative medicine using severe immunodeficient mice.Principal Investigator

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The studies on the practical application of NOD-sc/d, yc null mice allowing an efficient transplantation of human cells, to human disease modelsPrincipal Investigator

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Study on their experimetation of gerbils living in China for infectious diseases.Principal Investigator

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Generation of cloned mice and application on the field of laboratory animal sciencePrincipal Investigator

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Development of Chinese Lemming as an Experimental AnimalPrincipal Investigator

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ITO Mamoru 伊藤守