Ishibashi Kei 石橋啓

… Alternative Names

ISHIBASHI Kei 石橋啓

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Researcher Number	90347211
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2020 – 2023: 福島県立医科大学, 医学部, 博士研究員 2013 – 2019: 福島県立医科大学, 医学部, 准教授 2015: 福島県立医科大学, 医学部泌尿器科学講座, 准教授 2010 – 2012: 福島県立医科大学, 医学部, 講師 2010: 福島県立医科大学, 医学部, 助教 2004 – 2005: 福島県立医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Urology / Basic Section 56030:Urology-related Except Principal Investigator Urology / Basic Section 56030:Urology-related
Keywords	Principal Investigator 腎癌 / サイトカイン / SOCS3 / TRAIL / IL-6 / PD-L1 / glycoprotein H / antigenemia / acute rejection / cytomegalovirus … More / renal transplantation / 糖タンパクB / 糖タンパクH / アンチゲネミア / 急性拒絶反応 / サイトメガロウイルス / 腎移植 / 分子標的薬 / miRNA / インターフェロン / 腫瘍学 … More Except Principal Investigator 下部尿路機能障害 / 酸化ストレス / 過活動膀胱 / 慢性膀胱虚血 / 膀胱 / 細胞増殖 / 前立腺肥大症 / オートファジー / 自己免疫反応 / 微生物 / 細菌 / 補体 / 自己免疫疾患 / 動脈硬化 / NOＳアンカップリング / NOSアンカップリング / BH4 / 慢性虚血 / 尿中細菌叢 / 下部尿路症状 / マイクロバイオーム / Ｋチャネル / β3受容体 / cyclic AMP / β３受容体 / 弛緩 / Kチャネル / サイトメガロウイルス / 腎移植 / 慢性骨盤内虚血 / 陰茎 / 勃起障害 / 慢性骨盤虚血 / 閉塞膀胱 / 高脂肪食 / 膀胱部分閉塞 / 脂肪 / 膀胱機能 / 慢性炎症 / 脂肪組織 / 機能障害 / ケモカイン / モデル動物 / 創薬 / IGFBP3 / TGF-β / 繊維芽細胞 / 網羅的遺伝子解析 / 増殖因子 / サイトカイン / 筋線維芽細胞 / ゲノム薬理学 / オーダーメード医療 / 一塩基遺伝子多型 / 国際特許申請 / 国際学会での発表 / 学会賞の受賞 / 特許申請 / 国際学会での成果報告 / 学会賞 / 特許取得 / 腎癌予後不良38遺伝子 / 38遺伝子セット / 腎癌の網羅的遺伝子発現解析 / 腎癌の予後予測 / 骨盤臓器脱 / β2受容体 / 骨盤底筋 / 遺伝子多型 / 女性骨盤底 / ss2 受容体 Less

Endothelial nitric oxide synthase uncoupling cause lower urinary tract dysfunction associated with pelvic arterial occlusion
- Principal Investigator
  
  Akaihata Hidenori
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fukushima Medical University
腎癌による免疫代謝改変の制御を利用した新たな治療戦略に向けた基礎的研究Principal Investigator
- Principal Investigator
  
  石橋啓
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fukushima Medical University
Mechanisms of Inflammasome Regulation by Autoimmune Responses and Microbial Infection in Benign Prostatic Hyperplasia
- Principal Investigator
  
  Kojima Yoshiyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fukushima Medical University
尿中マイクロバイオーム解析による下部尿路症状の病態解明と治療ターゲットの探索
- Principal Investigator
  
  相川健
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Fukushima Medical University
PD-L1 and TRAIL expression in renal cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Ishibashi Kei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Search for therapeutic targets from novel prognostic-related genes based on comprehensive gene expression analysis of kidney cancer
- Principal Investigator
  
  Yanagida Tomohiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Basic research to realize personalized medicine based on pharmacogenomics and drug discovery in benign prostatic hyperplasia
- Principal Investigator
  
  Kojima Yoshiyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
The effect of perivesical fat on bladder dysfunction and the application to new treatment strategy
- Principal Investigator
  
  Aikawa Ken
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Development of novel treatment for ED and LUTS induced by chronic pelvic ischemia
- Principal Investigator
  
  Haga Nobuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
サイトメガロウイルスDNA多型による腎移植後の急性拒絶反応機序の解明
- Principal Investigator
  
  鶴谷善昭
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Blockade of IL-6 signal increases the susceptibility of renal cell carcinoma to interferonPrincipal Investigator
- Principal Investigator
  
  Ishibashi Kei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
clarification of human bladder smooth muscle and application to new treatment of lower urinary tract dysfunction
- Principal Investigator
  
  Ogawa Soichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Expression and role of miRNA in renal cell carcinoma which resists to immunotherapyPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Kei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Association between single nucleotide polymorphism of beta2-Adrenergic receptor gene and pelvic floor muscle function in POP and/or SUI patients
- Principal Investigator
  
  SHISHIDO Keiichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University
Immunopathological analysis of influence of cytomegalovirus to acute rejection after renal transplantationPrincipal Investigator
- Principal Investigator
  
  ISHIBASHI Kei
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Fukushima Medical University

All 2019 2018 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Complement activation by autoantigen recognition in the growth process of benign prostatic hyperplasia2019
- Author(s)
  Hata Junya、Machida Takeshi、Matsuoka Kanako、Hoshi Seiji、Akaihata Hidenori、Hiraki Hiroyuki、Suzuki Toshiyuki、Ogawa Soichiro、Kataoka Masao、Haga Nobuhiro、Ishibashi Kei、Homma Yoshimi、Sekine Hideharu、Kojima Yoshiyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 00-00
- DOI
  10.1038/s41598-019-57001-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07610, KAKENHI-PROJECT-19K09733, KAKENHI-PROJECT-17K16802
[Journal Article] Suppression of SOCS3 enhances TRAIL-induced cell growth inhibition through the upregulation of DR4 expression in renal cell carcinoma cells.2018
- Author(s)
  Yabe M, Ishibashi K, Onagi A, Tanji R, Honda-Takinami R, Koguchi T, Matsuoka K, Hoshi S, Hata J, Kataoka M, Ogawa S, Hiraki H, Haga N, Kojima Y.
- Journal Title
  
  Oncotarget.
  
  Volume: Aug 3;9(60) Pages: 31697-31708
- Data Source
  KAKENHI-PROJECT-16K11018
[Journal Article] Molecular classification of benign prostatic hyperplasia: A gene expression profiling study in a rat model.2016
- Author(s)
  Hata Junya, Satoh Yuichi, Akaihata Hidenori, Hiraki Hiroyuki, Ogawa Soichiro, Haga Nobuhiro, Ishibashi Kei, Aikawa Ken, Kojima Yoshiyuki.
- Journal Title
  
  International Journal of Urology.
  
  Volume: 23. 7. Issue: 7 Pages: 599-612
- DOI
  10.1111/iju.13106
- Data Source
  KAKENHI-PROJECT-26462448
[Journal Article] Pelvic arterial occlusive disease affects the Rho-A/Rho-kinase pathway in bladder smooth muscle.2015
- Author(s)
  Akaihata H, Nomiya M, Hata J, Yabe M, Takahashi N, Haga N, Kushida N, Ishibashi K, Aikawa K, Yamaguchi O, Kojima Y.
- Journal Title
  
  The Journal of Urology
  
  Volume: 194 Issue: 2 Pages: 706-713
- DOI
  10.1016/j.juro.2014.09.102
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462448
[Journal Article] Equally contributed Humanised antihuman IL-6R antibody with interferon inhibits renal cell carcinoma cell growth in vitro and in vivo through suppressed SOCS3 expression2012
- Author(s)
  Oguro T, Ishibashi K, Sugino T, Hashimoto K, Tomita S, Takahashi N, Yanagida T, Haga N, Aikawa K, Suzutani T, Yamaguchi O, Kojima Y
- Journal Title
  
  European J Cancer
  
  Volume: 26
- Data Source
  KAKENHI-PROJECT-22591773
[Journal Article] Suppression of SOCS3 increases susceptibility of renal cell carcinoma to INF-α2011
- Author(s)
  S.Tomita, K.Ishibashi, et. al.
- Journal Title
  
  Cancer Science
  
  Volume: Jan;102(1) Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591773
[Journal Article] Equally contributed Suppression of SOCS3 increases susceptibility of renal cell carcinoma to INF-α2011
- Author(s)
  Tomita S, Ishibashi K , Hashimoto K, Sugino T, Yanagida T, Kushida N, Shishido K, Aikawa K, Sato Y, Suzutani T, Yamaguchi O
- Journal Title
  
  Cancer Sci
  
  Volume: 102(1) Pages: 57-63
- Data Source
  KAKENHI-PROJECT-22591773
[Presentation] TKI induces angiogenesis and GLUT1 expression through IL-6 secretion on renal cell carcinoma cells2016
- Author(s)
  Kei Ishibashi
- Organizer
  第104回日本泌尿器科学会総会
- Place of Presentation
  宮城県
- Year and Date
  2016-04-23
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] 腎癌におけるIFN,分子標的薬投与によるNFkB,HSF1を介したIL-6の発現2016
- Author(s)
  石橋　啓
- Organizer
  第25回泌尿器科分子・細胞研究会
- Place of Presentation
  大阪
- Year and Date
  2016-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] 前立腺筋線維芽細胞の経時的変化からみた前立腺肥大症発症のメカニズムの解明.2016
- Author(s)
  秦淳也, 松岡香菜子, 胡口智之, 佐藤雄一, 赤井畑秀則, 小川総一郎, 片岡政雄, 羽賀宣博, 櫛田信博, 栁田知彦, 石橋啓, 相川健, 小島祥敬.
- Organizer
  第23回日本排尿機能学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-26462448
[Presentation] TKI induces GLUT1 expression through IL-6 secretion on renal cell carcinoma cells2016
- Author(s)
  Kei Ishibashi
- Organizer
  米国泌尿器科学会2016
- Place of Presentation
  米国サンディエゴ
- Year and Date
  2016-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] FDG-PETとナノ粒子造影剤を用いた腎癌におけるIL-6シグナル制御を利用したTKI投与後の血液再潅流抑制効果.2015
- Author(s)
  石橋　啓
- Organizer
  第103回日本泌尿器科学会総会
- Place of Presentation
  金沢
- Year and Date
  2015-04-18
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] IL-6 receptor antibody enhances the effect of TKI against renal cell carcinoma.2015
- Author(s)
  Kei Ishibashi
- Organizer
  米国泌尿器科学会2016
- Place of Presentation
  米国ニューオーリンズ
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] 腎癌におけるTKIとIL-6受容体抗体併用効果-動物用FDG-PETによる評価-.2015
- Author(s)
  石橋　啓
- Organizer
  第46回腎癌研究会
- Place of Presentation
  東京
- Year and Date
  2015-07-19
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] IL-6 and SOCS3 regulates cell proliferation in renal cell carcinoma cells AUA2013
- Author(s)
  Kei Ishibashi, Toshiki Oguro; Shin Kumagai; Masao Kataoka; Hidenori Akaihata; Ken Aikawa; Yoshiyuki Kojima
- Place of Presentation
  SanDiego USA.
- Year and Date
  2013-04-08
- Data Source
  KAKENHI-PROJECT-22591773
[Presentation] Combination therapy with humanized antihuman IL-6R antibody and interferon-α successfully prevents the growth of 786-O renal cell carcinoma cells2013
- Author(s)
  Kei Ishibashi, Toshiki Oguro; Shin Kumagai; Norio Takahashi; Nobuhiro Haga; Masanori Nomiya; Tomohiko Yanagida; Ken Aikawa Yoshiyuki Kojima
- Place of Presentation
  SanDiego USA
- Data Source
  KAKENHI-PROJECT-22591773
[Presentation] IL-6 and SOCS3 regulates cell proliferation in renal cell carcinoma cells2013
- Author(s)
  Ishibashi K
- Organizer
  AUA
- Place of Presentation
  SanDIego, USA
- Data Source
  KAKENHI-PROJECT-22591773
[Presentation] Combination therapy with humanized IL-6R antibody and interferon-α prevents the growth of renal cell carcinoma cells.2013
- Author(s)
  石橋　啓
- Organizer
  日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] ＩＬ-6-SOCS3の腎癌増殖に及ぼす影響について2013
- Author(s)
  石橋　啓
- Organizer
  第102回日本泌尿器科学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] IL-6 and SOCS3 regulates cell proliferation in renal cell carcinoma cells2013
- Author(s)
  Ishibashi K
- Organizer
  American Urological Association Annual Meeting 2013
- Place of Presentation
  SanDiego
- Data Source
  KAKENHI-PROJECT-25462492
[Presentation] Kojima TOCILIZUMAB CAN ENHANCE THE ANTI-TUMOR EFFECT OF IFN-a IN RENAL CELL CARCINOMA2012
- Author(s)
  T. Oguro, K. Ishibashi, T. Sugino, S. Kumagai, N. Takahashi, N. Haga, T. Yanagida, K. Aikawa, O. Yamaguchi, Y.
- Organizer
  37th ESMO Congress
- Place of Presentation
  Vienna
- Data Source
  KAKENHI-PROJECT-22591773
[Presentation] 前立腺肥大症モデルラットを用いた遺伝子ネットワーク解析ー前立腺肥大症特異発現遺伝子の同定と発症機序解明及び治療開発への展開
- Author(s)
  秦淳也、矢部通弘、佐藤雄一、赤井畑秀則、小川総一郎、片岡政雄、熊谷伸、熊谷研、羽賀宣博、櫛田信博、栁田知彦、石橋啓、相川健、小島祥敬
- Organizer
  第21回日本排尿機能学会
- Place of Presentation
  岡山
- Year and Date
  2014-09-17 – 2014-09-20
- Data Source
  KAKENHI-PROJECT-26462448

1. KOJIMA Yoshiyuki (60305539)

# of Collaborated Projects: 11 results

# of Collaborated Products: 5 results
2. AIKAWA Ken (80295419)

# of Collaborated Projects: 9 results

# of Collaborated Products: 4 results
3. YANAGIDA Tomohiko (20363765)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
4. HAGA Nobuhiro (50586617)

# of Collaborated Projects: 8 results

# of Collaborated Products: 5 results
5. HATA Junya (00769606)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
6. AKAIHATA Hidenori (70644178)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
7. TAKAHASHI Norio (50622312)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. OGAWA Soichiro (50554200)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
9. 櫛田信博 (30381396)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
10. SHISHIDO Keiichi (30285035)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. NOMIYA Masanori (00398348)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KATAOKA Masao (90554204)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. YABE Michihiro (30745782)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
14. SUZUTANI Tatsuo (40196895)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. SATO Yuichi (00706848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. TOMA Hiroshi (90075549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 鶴谷善昭 (80644179)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 徳本直彦 (30246540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 関根英治 (40363759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 町田豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishibashi Kei 石橋 啓

ISHIBASHI Kei 石橋 啓

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腎癌による免疫代謝改変の制御を利用した新たな治療戦略に向けた基礎的研究Principal Investigator

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PD-L1 and TRAIL expression in renal cell carcinomaPrincipal Investigator

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Blockade of IL-6 signal increases the susceptibility of renal cell carcinoma to interferonPrincipal Investigator

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Expression and role of miRNA in renal cell carcinoma which resists to immunotherapyPrincipal Investigator

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Immunopathological analysis of influence of cytomegalovirus to acute rejection after renal transplantationPrincipal Investigator

Ishibashi Kei 石橋啓

ISHIBASHI Kei 石橋啓

[Presentation] FDG-PETとナノ粒子造影剤を用いた腎癌におけるIL-6シグナル制御を利用したTKI投与後の血液再潅流抑制効果.2015