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Kumano Keiki  熊野 恵城

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… Alternative Names

熊野 恵城  クマノ ケイキ

KUMANO Keiki  熊野 恵城

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Researcher Number 90396721
Other IDs
Affiliation (Current) 2025: 武蔵野大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2023: 武蔵野大学, 薬学部, 教授
2022: 国際医療福祉大学, 薬学部, 教授
2013 – 2019: 関西医科大学, 医学部, 准教授
2010 – 2012: The University of Tokyo, 医学部附属病院, 講師
2009: 東京大学, 医学部附属病院, 助教 … More
2008 – 2009: The University of Tokyo, 医学部附属病院, 特任講師
2008: 東京大学, 医学部・附属病院, 持任講師
2007 – 2008: The University of Tokyo, HOSPITAL, ASSOCIATED PROFESSOR
2007: 東京大学, 医学部附属病院, 助教
2006: 東京大学, 医学部附属病院, 助手
2006: The University of Tokyo, Faculty of Medicine, Project Research Associate, 医学部附属病院, 特任助手
2006: 東京大学, 医学部附属病院, 特任助教
2006: 東京大学, 医学部附属病院, 特任助教授
2005: The University of Tokyo, Faculty of Medicine, Research Associate, 医学部附属病院, 研究拠点形成特任研究員
2005: 東京大学, 医学部附属病院, 研究拠点形成特任研究員(特任助手) Less
Review Section/Research Field
Principal Investigator
Hematology / Respiratory organ internal medicine / Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Hematology / Biological Sciences
Keywords
Principal Investigator
Notch / 幹細胞 / Bmi1 / 系譜追跡 / 肺がん / ニッチ / 白血病幹細胞 / 前がん病変 / クローン性増殖 / 食道がん … More / がん幹細胞 / BASC / Kras / niche / Hematopoietic stem ce / 血液内科 / 造血幹細胞 / iPS cells / iPS細胞 … More
Except Principal Investigator
造血器腫瘍 / 白血病 / 癌 / 遺伝子 / CNAG / LOH / マイクロアレイ / UPD / 癌抑制遺伝子 / 悪性リンパ腫 / SNPアレイ / Blimp-1 / 細胞周期 / 遺伝子変異 / Notch / シグナル伝達 / Blimp1 / アレル不均衡 / MDS / ゲノム解析 / cell cycle / tumor suppressor / LEUKEMIA / MICROARRAY / ALLELIC IMBALANCES / GENETICS / CANCER / 遺伝学 / development, differentiation / translational research / cells, tissues / transplantation, regeneration medicine / 再生医学 / 発生・分化 / トランスレーショナルリサーチ / 細胞・組織 / 移植・再生医療 / Allele-specific analysis / SNP array / Copy number analysis / Leukemia / Affymetrix / モデルマウス / アレル特異的解析 / コピー数解析 / BCL11B / CD28 / CD2 / HTLV-1 / ATL / リシーケンス / ゲノム異常 / 遺伝子診断 / 分子標的 / ゲノミクス / Hes / 遺伝子異常 / 細胞環境 / 血管新生 / 造血幹細胞移植学 / 臨床 / 内科 / ゲノムコピー数 / T細胞性急性リンパ性白血病 / 免疫学 / 感染症 / アレルギー・ぜんそく / 造血システム / 高密度オリゴヌクレオチドアレイ / ゲノムコピー数異常 / ゲノム / チロシンキナーゼ / c-Cb1 / CMML / 6q23 / 11qUPD / A20 / ホジキンリンパ腫 Less
  • Research Projects

    (17 results)
  • Research Products

    (99 results)
  • Co-Researchers

    (17 People)
  •  The analysis of molecular pathogenesis of esophageal cancer from precancerous lesions showing clonal proliferationPrincipal Investigator

    • Principal Investigator
      熊野 恵城
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Musashino University
      International University of Health and Welfare
  •  Establishment of new target therapy depending on the origin of lung cancer stem cellPrincipal Investigator

    • Principal Investigator
      KUMANO Keiki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kansai Medical University
  •  Establishment of new target therapy depending on the origin of lung cancer stem cellPrincipal Investigator

    • Principal Investigator
      KUMANO Keiki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kansai Medical University
  •  The analysis of leukemia stem cell using iPS cell technologyPrincipal Investigator

    • Principal Investigator
      KUMANO keiki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Kansai Medical University
      The University of Tokyo
  •  Identification of gene targets for molecular diagnosis and therapeutics in hematopoietic malignancies based on advanced genomics

    • Principal Investigator
      OGAWA Seishi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Analysis of regulatory mechanism of hematopoiesis and exploration of the pathogenesis of hematopoietic neoplasms through comprehensive genetic analysis

    • Principal Investigator
      OGAWA Seishi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  The role of Notch signaling in the leukemia stem cells.Principal Investigator

    • Principal Investigator
      KUMANO Keiki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  造血器腫瘍における癌関連遺伝子の解析

    • Principal Investigator
      半下石 明
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Role of cell environmental signaling in the establishment of hematopoietic malignancies

    • Principal Investigator
      CHIBA Shigeru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  Notchシグナル亢進による腫瘍化機構の解明

    • Principal Investigator
      千葉 滋
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  ハイドロキシアパタイトマイクロキャリアーを利用した造血幹細胞増幅法と移植法の開発

    • Principal Investigator
      千葉 滋
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  GENMOME-WIDEANALYSIS OF GENETIC BASIS OF HEMATOLOGICAL MALIGNANCIES

    • Principal Investigator
      OGAWA SEISHI
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Functional analyses of the new tumor suppressor candidate gene in hematological malignancies

    • Principal Investigator
      HANGAISHI Akira
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  The role of Notch signaling in the regulation of hematopoietic stem cells in the nichePrincipal Investigator

    • Principal Investigator
      KUMANO Keiki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Notchシグナル阻害によるマスト細胞制御・新たな自己免疫疾患治療法開発に向けて

    • Principal Investigator
      CHIBA Shigeru
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Hematopoietic stem cell regulation by the Notch signaling-including hematopoietic stem cell induction from human embryonic stem cells-

    • Principal Investigator
      CHIBA Shigeru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Exploring leukemogenic mechanism using genomic analysis and mouse genetics.

    • Principal Investigator
      OGAWA Seishi
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo

All 2024 2022 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2006 2005 Other

All Journal Article Presentation Book Other

  • [Book] みんなに役立つ造血幹細胞移植の基礎と臨床2008

    • Author(s)
      熊野恵城、千葉滋
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Book] Annual Review 血液20082008

    • Author(s)
      熊野恵城、黒川峰夫
    • Total Pages
      9
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Book] Annual Review血液2008

    • Author(s)
      熊野恵城、黒川峰夫
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate.2018

    • Author(s)
      1.Taoka K, Arai S, Kataoka K, Hosoi M, Miyauchi M, Yamazaki S, Honda A, Aixinjueluo W, Kobayashi T, Kumano K, Yoshimi A, Otsu M, Niwa A, Nakahata T, Nakauchi H, Kurokawa M.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 15855-15867

    • DOI

      10.1038/s41598-018-34193-1

    • NAID

      120006534582

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09631, KAKENHI-PROJECT-18K16111, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-18H04052
  • [Journal Article] ADAM8 Is an Antigen of Tyrosine Kinase Inhibitor-Resistant Chronic Myeloid Leukemia Cells Identified by Patient-Derived Induced Pluripotent Stem Cells2018

    • Author(s)
      Miyauchi Masashi、Koya Junji、Arai Shunya、Yamazaki Sho、Honda Akira、Kataoka Keisuke、Yoshimi Akihide、Taoka Kazuki、Kumano Keiki、Kurokawa Mineo
    • Journal Title

      Stem Cell Reports

      Volume: 10 Issue: 3 Pages: 1115-1130

    • DOI

      10.1016/j.stemcr.2018.01.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01196, KAKENHI-PROJECT-16K19568, KAKENHI-PROJECT-17K09631
  • [Journal Article] Intestinal stem cells contribute to the maturation of the neonatal small intestine and colon independently of digestive activity.2017

    • Author(s)
      Yanai H, Atsumi N, Tanaka T, Nakamura N, Komai Y, Omachi T, Tanaka K, Ishigaki K, Saiga K, Ohsugi H, Tokuyama Y, Imahashi Y, Ohe S, Hisha H, Yoshida N, Kumano K, Kon M, Ueno H.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 9891-9901

    • DOI

      10.1038/s41598-017-09927-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09631, KAKENHI-PROJECT-15H02364
  • [Journal Article] Intestinal cancer stem cells marked by Bmi1 or Lgr5 expression contribute to tumor propagation via clonal expansion.2017

    • Author(s)
      Hirotsugu Yanai, Naho Atsumi, Toshihiro Tanaka, Naohiro Nakamura, Yoshihiro Komai, Taichi Omachi, Kiyomichi Tanaka, Kazuhiko Ishigaki, Kazuho Saiga, Haruyuki Ohsugi, Yoko Tokuyama, Yuki Imahashi, Shuichi Ohe, Hiroko Hisha, Naoko Yoshida, Keiki Kumano, Masanori Kon and Ueno H.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 41838-41847

    • DOI

      10.1038/srep41838

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02364, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-15K14531, KAKENHI-PROJECT-17K09631
  • [Journal Article] Bmi1-positive cells in the lingual epithelium could serve as cancer stem cells in tongue cancer2016

    • Author(s)
      T Tanaka, N Atsumi, N Nakamura, H Yanai, Y Komai, T Omachi, K Tanaka, K Ishigaki, K Saiga, H Ohsugi, Y Tokuyama, Y Imahashi, H Hisha, N Yoshida, K Kumano, K Okazaki, and Ueno H
    • Journal Title

      Scientific Reports

      Volume: 6 Issue: 1 Pages: 39386-39391

    • DOI

      10.1038/srep39386

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02364, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-15K14531
  • [Journal Article] Targeted gene correction of RUNX1 in induced pluripotent stem cells derived from familial platelet disorder with propensity to myeloid malignancy restores normal megakaryopoiesis.2015

    • Author(s)
      2.Iizuka H, Kagoya Y, Kataoka K, Yoshimi A, Miyauchi M, Taoka K, Kumano K, Yamamoto T, Hotta A, Arai S, Kurokawa M.
    • Journal Title

      Exp Hematol.

      Volume: 43 Issue: 10 Pages: 849-857

    • DOI

      10.1016/j.exphem.2015.05.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461170, KAKENHI-PUBLICLY-15H01481
  • [Journal Article] Maintenance of sweat glands by stem cells located in the acral epithelium.2015

    • Author(s)
      1.Ohe S, Tanaka T, Yanai H, Komai Y, Omachi T, Kanno S, Tanaka K, Ishigaki K, Saiga K, Nakamura N, Ohsugi H, Tokuyama Y, Atsumi N, Hisha H, Yoshida N, Kumano K, Yamazaki F, Okamoto H, Ueno H.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 466 Issue: 3 Pages: 333-338

    • DOI

      10.1016/j.bbrc.2015.09.022

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-15K14531
  • [Journal Article] Intracellular signals of lung cancer cells as possible therapeutic targets.2015

    • Author(s)
      Tanaka K, Kumano K, Ueno H
    • Journal Title

      Cancer Science

      Volume: 未定 Issue: 5 Pages: 489-496

    • DOI

      10.1111/cas.12643

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-15K14531, KAKENHI-PROJECT-15H02364
  • [Journal Article] Bmi1 expression in long-term germ stem cells.2014

    • Author(s)
      Komai Y, Tanaka T, Tokuyama Y, Yanai H, Ohe S, Omachi T, Atsumi N, Yoshida N, Kumano K, Hisha H, Matsuda T, Ueno H.
    • Journal Title

      Scientific Reports

      Volume: 4 Issue: 1 Pages: 6175-6186

    • DOI

      10.1038/srep06175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26461170
  • [Journal Article] Generation of induced pluripotent stem cells derived from primary and secondary myelofibrosis patient samples2014

    • Author(s)
      Hosoi M, Kumano K, Taoka K, Arai S, Kataoka K, Ueda K, Kamikubo Y, Takayama N, Otsu M, Eto K, Nakauchi H, Kurokawa M
    • Journal Title

      Exp Hematol

      Volume: (in press) Issue: 9 Pages: 816-25

    • DOI

      10.1016/j.exphem.2014.03.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25461420, KAKENHI-PROJECT-26461170
  • [Journal Article] The IL-2/CD25 Axis Maintains Distinct Subsets of Chronic M yeloid Leukemia-initiating Cells.2014

    • Author(s)
      Kobayashi CI, Takubo K, Kobayashi H, Nakamura-Ishizu A, Honda H, Kataoka K, Kumano K, Akiyama H, Sudo T, Kurokawa M, Suda T.
    • Journal Title

      Blood

      Volume: 123 Issue: 16 Pages: 2540-2549

    • DOI

      10.1182/blood-2013-07-517847

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11J04561, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689049, KAKENHI-PUBLICLY-25118724, KAKENHI-PROJECT-25640065, KAKENHI-PROJECT-26221309, KAKENHI-PROJECT-26461170
  • [Journal Article] Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.2014

    • Author(s)
      Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M.
    • Journal Title

      J Clin Invest.

      Volume: 124 Issue: 2 Pages: 528-542

    • DOI

      10.1172/jci68101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-26860474
  • [Journal Article] The shortest isoform of C/EBPβ, Liver inhibitory protein (LIP) , collaborates with Evi1 to induce AML in a mouse BMT model2013

    • Author(s)
      Okochi, N., Yoshimi, A., Sato, T., Ikeda, T., Kumano, K., Taoka, K., Sato, Y., Shinohara, A., Tsuruta, A., Masuda, A., Yokota, H., Yatomi, Y., Takahashi, K., Kitaura, J., Kitamura, T. and Kurokawa, M
    • Journal Title

      Blood

      Volume: 121 Issue: 20 Pages: 4142-4155

    • DOI

      10.1182/blood-2011-07-368654

    • NAID

      10031196292

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24790961, KAKENHI-PROJECT-24790964, KAKENHI-PUBLICLY-23130503
  • [Journal Article] The significance of free light chain measurements in the diagnosis of myelomatous pleural effusion.2013

    • Author(s)
      Tsukamoto A, Yoshiki Y, Yamazaki S, Kumano K, Nakamura F, Kurokawa M.
    • Journal Title

      Ann Hematol.

      Volume: 93 Issue: 3 Pages: 507-508

    • DOI

      10.1007/s00277-013-1818-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Journal Article] Generation of iPS cells from normal and malignant hematopoietic cells.2013

    • Author(s)
      Kumano K, Arai S, Kurokawa M.
    • Journal Title

      Int J Hematol.

      Volume: 98 Issue: 2 Pages: 145-182

    • DOI

      10.1007/s12185-013-1385-x

    • NAID

      10031194728

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-25670445
  • [Journal Article] Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation.2012

    • Author(s)
      Yoshimi M, Goyama S, Kawazu M, Nakagawa M, Ichikawa M, Imai Y, Kumano K, Asai T, Mulloy JC, Kraft AS, Takahashi T, Shirafuji N, Kurokawa M.
    • Journal Title

      Eur J Immunol.

      Volume: 42 Issue: 4 Pages: 1044-1050

    • DOI

      10.1002/eji.201040746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24659457, KAKENHI-PUBLICLY-23130503
  • [Journal Article] Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia2012

    • Author(s)
      Keiki Kumano
    • Journal Title

      BLOOD

      Volume: 119 Issue: 26 Pages: 6234-6242

    • DOI

      10.1182/blood-2011-07-367441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591026, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23790775, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24659489, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23112504, KAKENHI-PUBLICLY-23130503
  • [Journal Article] ヒトCML検体からのiPS細胞の作製と解析2012

    • Author(s)
      熊野恵城、黒川峰夫
    • Journal Title

      血液内科

      Volume: 65 Pages: 710-716

    • NAID

      40019515733

    • Data Source
      KAKENHI-PROJECT-23591369
  • [Journal Article] Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine2011

    • Author(s)
      Sakata-Yanagimoto M, Sakai T, Miyake Y, Saito T, Maruyama H, Morishita Y, Nakagami-Yamaguchi E, Kumano K, Yagita H, Fukayama M, Ogawa S, Kurokawa M, Yasutomo K, Chiba S
    • Journal Title

      Blood

      Volume: 117 Issue: 1 Pages: 128-134

    • DOI

      10.1182/blood-2010-07-289611

    • NAID

      120007137632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-22500760, KAKENHI-PROJECT-23591369
  • [Journal Article] Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity2011

    • Author(s)
      Keisuke Kataoka
    • Journal Title

      The Journal of Experimental Medicine

      Volume: 208 Issue: 12 Pages: 2403-2416

    • DOI

      10.1084/jem.20110447

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J04996, KAKENHI-PROJECT-19679004, KAKENHI-PROJECT-20229008, KAKENHI-PUBLICLY-23130503, KAKENHI-PROJECT-23591369
  • [Journal Article] Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through downregulation of p19ARF2011

    • Author(s)
      黒川峰夫, 他
    • Journal Title

      Blood

      Volume: 118 Issue: 9 Pages: 2541-2550

    • DOI

      10.1182/blood-2010-10-315440

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19679004, KAKENHI-PROJECT-22790901, KAKENHI-PUBLICLY-23130503, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23591409
  • [Journal Article] Outcome of medium-dose VP-16/CY/TBI superior to CY/TBI as a conditioning regimen for allogeneic stem cell transplantation in adult patients with acute lymphoblastic leukemia2011

    • Author(s)
      Shigematsu A, et al
    • Journal Title

      International Journal of Hematology

      Volume: 94(5) Issue: 5 Pages: 463-471

    • DOI

      10.1007/s12185-011-0944-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591239, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23791077
  • [Journal Article] AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors2011

    • Author(s)
      Masahiro Nakagawa
    • Journal Title

      Blood

      Volume: 118 Issue: 25 Pages: 6626-6637

    • DOI

      10.1182/blood-2010-12-326710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J04996, KAKENHI-PROJECT-19679004, KAKENHI-PROJECT-22790901, KAKENHI-PUBLICLY-23130503, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23591409
  • [Journal Article] The effect of iron overload and chelation on erythroid differentiation2011

    • Author(s)
      Taoka K, Kumano K, Nakamura F, Hosoi M, Goyama S, Imai Y, Hangaishi A, Kurokawa M
    • Journal Title

      International Journal of Hematology

      Volume: 95 Issue: 2 Pages: 149-159

    • DOI

      10.1007/s12185-011-0988-3

    • NAID

      10030267276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19679004, KAKENHI-PROJECT-22790902, KAKENHI-PROJECT-23591369
  • [Journal Article] 造血細胞のリプログラミングの現状と血液疾患治療への応用2010

    • Author(s)
      熊野恵城
    • Journal Title

      血液・腫瘍科 60

      Pages: 460-464

    • NAID

      40019064565

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] 造血細胞のリプログラミングの現状と血液疾患治療への応用2010

    • Author(s)
      熊野恵城
    • Journal Title

      血液・腫瘍科

      Volume: 60 Pages: 460-464

    • NAID

      40019064565

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.2010

    • Author(s)
      Nakahara F, Sakata-Yanagimoto M, Komeno Y, Kato N, Uchida T, Haraguchi K, Kumano K, Harada Y, Harada H, Kitaura J, Ogawa S, Kurokawa M, Kitamura T, Chiba S.
    • Journal Title

      Blood. 115

      Pages: 2872-2881

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] The role of Runx1/AML1 and Evi-1 in the regulation of he matopoietic stem cells.2010

    • Author(s)
      Kumano Keiki, Mineo Kurokawa
    • Journal Title

      J Cell Physiol.

      Volume: 222 Pages: 282-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] The role of Runx1/AML1 and Evi-1 in the regulation of hematopoietic stem cells.2010

    • Author(s)
      Kumano K, Kurokawa M.
    • Journal Title

      J Cell Physiol. 222

      Pages: 282-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Hesl immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.2010

    • Author(s)
      Nakahara F, Sakata-Yanagimoto M, Komeno Y, Kato N, Uchida T, Haraguchi K, Kumano K, Harada Y, Harada H, Kitaura J, Ogawa S, Kurokawa M, Kitamura T, Chiba S.
    • Journal Title

      Blood 115

      Pages: 2872-2881

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.2010

    • Author(s)
      Nakahara F, Sakata-Yanagimoto M, Komeno Y, Kato N, Uchida T, Haraguchi K, Kumano K, Harada Y, Harada H, Kitaura J, Ogawa S, Kurokawa M, Kitamura T, Chiba S.
    • Journal Title

      Blood.

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.2009

    • Author(s)
      Haraguchi K, Suzuki T, Koyama N, Kumano K, Nakahara F, Matsumoto A, Yokoyama Y, Sakata-Yanagimoto M, Masuda S, Takahashi T, Kamijo A, Takahashi K, Takanashi M, Okuyama Y, Yasutomo K, Sakano S, Yagita H, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      J Immunol. 182

      Pages: 6168-6178

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL-15.2009

    • Author(s)
      Haraguchi K, Suzuki T, Koyama N, Kumano K, Nakahara F, Matsumoto A, Yokoyama Y, Sakata-Yanagimoto M, Masuda S, Takahashi T, Kamijo A, Takahashi K, Takanashi M, Okuyama Y, Yasutomo K, Sakano S, Yagita H, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      J Immunol. 182

      Pages: 6168-6178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] Derivation of functional mature neutrophils from human embryonic stem cells.2009

    • Author(s)
      Yokoyama Y, Suzuki T, Sakata-Yanagimoto M, Kumano K, Higashi K, Takato T, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Blood. 113

      Pages: 6584-6592

    • NAID

      120007131544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] 造血ニッチと幹細胞制御2009

    • Author(s)
      熊野恵城,黒川峰夫
    • Journal Title

      血液フロンティア 19

      Pages: 446-451

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] 幹細胞の基礎研究:造血幹細胞2009

    • Author(s)
      熊野恵城,黒川峰夫
    • Journal Title

      医学のあゆみ 229

      Pages: 698-702

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] 造血幹細胞2009

    • Author(s)
      熊野恵城、黒川峰夫
    • Journal Title

      医学のあゆみ 229

      Pages: 698-702

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model.2009

    • Author(s)
      Masuda S, Kumano K, Suzuki T, Tomita T, Iwatsubo T, Natsugari H, Tojo A, Shibutani M, Mitsumori K, Hanazono Y, Ogawa S, Kurokawa M, Chiba S.
    • Journal Title

      Cancer Sci. 100

      Pages: 2444-2450

    • NAID

      10027198807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Derivation of functional mature neutrophils from human embryonic stem cells.2009

    • Author(s)
      Yokoyama Y, Suzuki T, Sakata-Yanagimoto M, Kumano K, Higashi K, Takato T, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Blood. 113

      Pages: 6584-6592

    • NAID

      120007131544

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
    • Journal Title

      Nature. 460

      Pages: 904-908

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] 造血幹細胞2009

    • Author(s)
      熊野恵城,黒川峰夫
    • Journal Title

      医学のあゆみ 229

      Pages: 698-702

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] The role of Runxl/AML1 and Evi-1 in the regulation of Hemato poietic Stem Cells2009

    • Author(s)
      Keiki Kumano, Mineo Kurokawa
    • Journal Title

      J.Cell.Physiol. 222

      Pages: 282-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.2009

    • Author(s)
      Lee SY, Kumano K, Nakazaki K, Sanada M, Matsumoto A, Yamamoto G, Nannya Y, Suzuki R, Ota S, Ota Y, Izutsu K, Sakata-Yanagimoto M, Hangaishi A, Yagita H, Fukayama M, Seto M, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Cancer Sci. 100

      Pages: 920-926

    • NAID

      10025145854

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] 白血病幹細胞を標的とした新規治療法2009

    • Author(s)
      熊野恵城, 黒川峰夫
    • Journal Title

      Biotherapy 23

      Pages: 371-378

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.2009

    • Author(s)
      Lee SY, Kumano K, Nakazaki K, Sanada M, Matsumoto A, Yamamoto G, Nannya Y, Suzuki R, Ota S, Ota Y, Izutsu K, Sakata-Yanagimoto M, Hangaishi A, Yagita H, Fukayama M, Seto M, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Cancer Sci. 100

      Pages: 920-926

    • NAID

      10025145854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.
    • Journal Title

      Nature. 460

      Pages: 904-908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Derivation of functional mature neutrophils from human embryonic stem cells.2009

    • Author(s)
      Yokoyama Y, Suzuki T, Sakata-Yanagimoto M, Kumano K, Higashi K, Takato T, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Blood. 113

      Pages: 6584-92

    • NAID

      120007131544

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009

    • Author(s)
      Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.
    • Journal Title

      Nature. 460

      Pages: 904-908

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] Gain-of-function mutations and copy number increases of Notch2 in diffuse large B-cell lymphoma.2009

    • Author(s)
      Lee SY, Kumano K, Nakazaki K, Sanada M, Matsumoto A, Yamamoto G, Nannya Y, Suzuki R, Ota S, Ota Y, Izutsu K, Sakata-Yanagimoto M, Hangaishi A, Yagita H, Fukayama M, Seto M, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Cancer Sci. 100

      Pages: 920-6

    • NAID

      10025145854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] 白血病幹細胞を標的とした新規治療法2009

    • Author(s)
      熊野恵城,黒川峰夫
    • Journal Title

      Biotherapy 23

      Pages: 371-378

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Notch activation induces the generation of functional NK cells from human cord blood CD34-positive cells devoid of IL 15.2009

    • Author(s)
      Haraguchi K, Suzuki T, Koyama N, Kumano K, Nakahara F, Matsumoto A, Yokoyama Y, Sakata-Yanagimoto M, Masuda S, Takahashi T, Kamijo A, Takahashi K, Takanashi M, Okuyama Y, Yasutomo K, Sakano S, Yagita H, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      J Immunol. 182

      Pages: 6168-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      Kumano K, Masuda S, Sata M, et. al.
    • Journal Title

      Pigment Cell and Melanoma Research 21

      Pages: 70-78

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] Both Notchl and Notch2 contribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      熊野 恵城、他
    • Journal Title

      Pigment Cell and Melanoma Research 21

      Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390258
  • [Journal Article] 造血器腫瘍におけるがん幹細胞研究の進展:AML幹細胞研究の進展2008

    • Author(s)
      熊野恵城、黒川峰夫
    • Journal Title

      血液・腫瘍科 56

      Pages: 694-700

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      Kumano K, Masuda S, Sata M eta al.
    • Journal Title

      Pigment Cell Melanoma Research 21

      Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate.2008

    • Author(s)
      Sakata-Yanagimoto M, Nakagami-Yamaguchi E, Saito T, Kumano K, Yasutomo K, Ogawa S, Kurokawa M, Chiba S.
    • Journal Title

      Proc Natl Acad Sci USA. 105

      Pages: 7839-7844

    • NAID

      120007138253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      Kumano K, Masuda S, Sata M, Saito T, Lee SY, Sakata-Yanagimoto M, Tomita T, Iwatsubo T, Natsugari H, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Pigment Cell Research

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Journal Article] 白血病幹細胞を標的とした新規治療法の開発2008

    • Author(s)
      熊野恵城、黒川峰夫
    • Journal Title

      医学のあゆみ 227

      Pages: 83-86

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate.2008

    • Author(s)
      Sakata-Yanagimoto M, Nakagami-Yamaguchi E, Saito T, Kumano K, Yasutomo K, Ogawa S, Kurokawa M, Chiba S.
    • Journal Title

      Proc Natl Acad Sci U S A. 105

      Pages: 7839-7844

    • NAID

      120007138253

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] Both Notchl and Notch2 contribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      Kumano K, Masuda S, Sata M, Saito To, Lee SY, Sakata-Yanagimoto M, Tomita T, Iwatsubo T, Natsugari H, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Pigment Cell Melanoma Res. 21

      Pages: 70-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate.2008

    • Author(s)
      Sakata-Yanagimoto M, Nakagami-Yamaguchi E, Saito T, Kumano K, Yasutomo K, Ogawa S, Kurokawa M, Chiba S.
    • Journal Title

      Proc Natl Acad Sci U S A. 105

      Pages: 7839-44

    • NAID

      120007138253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate2008

    • Author(s)
      Sakata-Yanagimoto M, Nakagami- Yamaguchi E, Saito T, Kumano K, Yasutomo K, Ogawa S, Kurokawa M, Chiba S.
    • Journal Title

      Proc Natl Acad Sci USA 105(22)

      Pages: 7839-7844

    • NAID

      120007138253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390258
  • [Journal Article] TEL-AML1関連小児白血病発症過程で、がん化過程を開始する細胞とがんを伝播する細胞2008

    • Author(s)
      熊野恵城、黒川峰夫
    • Journal Title

      分子細胞治療 7

      Pages: 470-471

    • Data Source
      KAKENHI-PROJECT-20591111
  • [Journal Article] Both Notch1 and Notch2 conbribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      熊野 恵城, 他
    • Journal Title

      Pigment Cell and Melanoma Research 21

      Pages: 70-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013012
  • [Journal Article] Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis.2008

    • Author(s)
      Kumano K, Masuda S, Sata M, Saito T, Lee SY, Sakata-Yanagimoto M, Tomita T, Iwatsubo T, Natsugari H, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Pigment Cell Research.

    • Data Source
      KAKENHI-PROJECT-17013022
  • [Journal Article] Both Notch1 and Notch2 contribute to the regulation of melanocyte homeostasis2008

    • Author(s)
      Kumano K, Masuda S, Sata M, et. al.
    • Journal Title

      Pigment Cell and Melanoma Research 21

      Pages: 70-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] Highly efficient ex vivo expansion of human hematopoietic stem cells using Deltal-Fc chimeric protein.2006

    • Author(s)
      Suzuki T, Yokoyama Y, Kumano K, Takanashi M, Kozuma S, Takato T, Nakahata T, Nishikawa M, Sakano S, Kurokawa M, Ogawa S, Chiba S.
    • Journal Title

      Stem Cells 24

      Pages: 2456-2465

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390274
  • [Journal Article] Highly efficient ex vivo expansion of human hematopoietic stem cells using Delta1-Fc chimeric protein.2006

    • Author(s)
      Suzuki T, Yokoyama Y, Kumano K, et. al.
    • Journal Title

      Stem Cells. 24

      Pages: 2456-2465

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] Notchシグナルと造血器腫瘍2006

    • Author(s)
      熊野 恵城
    • Journal Title

      血液・腫瘍科 52

      Pages: 639-639

    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] AML1/Runx1 rescues Notchl-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.2006

    • Author(s)
      Nakagawa M, Ichikawa M, Kumano K, Goyama S, Kawazu M, Asai T, Ogawa S, Kurokawa M, Chiba S.
    • Journal Title

      Blood 108

      Pages: 3329-3334

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390274
  • [Journal Article] Highly efficient ex vivo expansion of human hematopoietic stem cells using Deltal-Fc chimeric protein2006

    • Author(s)
      Suzuki T, Yokoyama Y, Kumano K, et. al.
    • Journal Title

      Stem Cells 24

      Pages: 2456-2465

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis.2006

    • Author(s)
      Nakagawa M, Ichikawa M, Kumano K, et. al.
    • Journal Title

      Blood. 108

      Pages: 3329-3334

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] AML1/Runx1 rescues Notch 1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis2006

    • Author(s)
      Nakagawa M, Ichikawa M, Kumano K, et. al.
    • Journal Title

      Blood 108

      Pages: 3329-3334

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Journal Article] Mutations of the Notch1 gene in T -cell acute lymphoblastic leukemia : analysis in adults and children.2005

    • Author(s)
      Lee SY, Kumano K, Masuda S, Hangaishi A, Takita J, Nakazaki K, Kurokawa M, Hayashi Y, Ogawa S, Chiba S.
    • Journal Title

      Leukemia 19

      Pages: 1841-1843

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390272
  • [Journal Article] Mutations of the Notchl gene in T-cell acute lymphoblastic leukemia : analysis in adults and children.2005

    • Author(s)
      Lee SY, Kumano K, Masuda S, Hangaishi A, Takita J, Nakazaki K, Kurokawa M, Hayashi Y, Ogawa S, Chiba S.
    • Journal Title

      Leukemia 19

      Pages: 1841-1843

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390274
  • [Journal Article] Hematopoietic stem cells expanded by fibroblast growth factor-1 are excellent targets for retrovirus-mediated gene delivery.2005

    • Author(s)
      Crcareva A, Saito T, Kunisato A, Kumano K, Suzuki T, Sakata-Yanagimoto M, Kawazu M, Stojanovic A, Kurokawa M, Ogawa S. Chiba S.
    • Journal Title

      Exp Hematol 33

      Pages: 1459-1469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390274
  • [Journal Article] Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine.

    • Author(s)
      Sakata-Yanagimoto M, Sakai T, Miyake Y, Saito T, Maruyama M, Morishita Y, Nakagami-Yamaguchi E, Kumano K, Yagita Y, Fukayama M, Ogawa S, Kurokawa M, Yasutomo K, Chiba S.
    • Journal Title

      Blood In press

    • NAID

      120007137632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390266
  • [Presentation] Newly identified WDFY4 is one of the promoting molecules for TLR7-induced lethal inflammation.2024

    • Author(s)
      Yusuke Murakami, Ryutaro Fukui, Kiyoshi Yamaguchi, Reika Tanaka, Tomoya Narita, Yoichi Furukawa, Kensuke Miyake, Keiki Kumano.
    • Organizer
      第52回 日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07968
  • [Presentation] マウスモデルの確立による肺がんの起源細胞と発症メカニズムの同定2022

    • Author(s)
      熊野恵城、小嶋凜太郎、浅野秀樹、 尾形浩志
    • Organizer
      第12回国際医療福祉大学学会学術大会
    • Data Source
      KAKENHI-PROJECT-22K07968
  • [Presentation] Generation of induced pluripotent stem cells from primary hematological malignancies2012

    • Author(s)
      Keiki Kumano, Shunya Arai, Masataka Hosoi, Kazuki Taoka, Koki Ueda, Kumi Nakazaki, Yasuhiko Kamikubo, Mineo Kurokawa
    • Organizer
      International Society for Stem cell Research (ISSCR) annual meeting
    • Place of Presentation
      Yokohama
    • Year and Date
      2012-06-12
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] Generation of induced pluripotent stem cells from primary hematological malignancies.2012

    • Author(s)
      Keiki Kumano, Shunya Arai, Masataka Hosoi, Kazuki Taoka, Koki Ueda, Kumi Nakazaki, Yasuhiko Kamikubo, Mineo Kurokawa.
    • Organizer
      International Society for Stem cell Research (ISSCR) annual meeting
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] Generation of induced pluripotent stem cells from primary hematological malignancies and search for the novel targeted therapy2011

    • Author(s)
      Keiki Kumano, Shunya Arai, Masataka Hosoi, Kazuki Taoka, Koki Ueda, Kumi Nakazaki, Yasuhiko Kamikubo, Mineo Kurokawa
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-04
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] Generation of induced pluripotent stem cells from primary hematological malignancies and search for the novel targeted therapy2011

    • Author(s)
      Keiki Kumano, Shunya Arai, Masataka Hosoi, Kazuki Taoka, Koki Ueda, Kumi Nakazaki, Yasuhiko Kamikubo, Mineo Kurokawa
    • Organizer
      The 9^<th> Stem Cell Research Symposium
    • Place of Presentation
      Tokyo
    • Year and Date
      2011-05-13
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] iPS細胞による白血病の病態解析2011

    • Author(s)
      熊野恵城、黒川峰夫
    • Organizer
      第15回日本がん分子標的治療学会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-23
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] Generation of induced pluripotent stem cells from primary hematological malignancies2011

    • Author(s)
      Keiki Kumano, Shunya Arai, Masataka Hosoi, Kazuki Taoka, Koki Ueda, Kumi Nakazaki, Yasuhiko Kamikubo, Mineo Kurokawa
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-15
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] Generation of induced pluripotent stem cells from primary hematological malignancies and search for the novel targeted therapy.2011

    • Author(s)
      Keiki Kumano, Shunya Arai, Masataka Hosoi, Kazuki Taoka, Koki Ueda, Kumi Nakazaki, Yasuhiko Kamikubo, and Mineo Kurokawa.
    • Organizer
      The 9th Stem Cell Research Symposium
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-23591369
  • [Presentation] Generation of Induced Pluripotent Stem Cells From Primary Chronic Myelogenous Leukemia Patient Sample.2010

    • Author(s)
      Keiki Kumano, Shunya Arai, Koki Ueda, et al.
    • Organizer
      52^<nd> ASH Annual Meeting
    • Place of Presentation
      Orland, Florida, USA.
    • Year and Date
      2010-12-04
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Presentation] Generation of Induced Pluripotent Stem Cells From Primary Chronic Mvelogenous Leukemia Patient Sample.2010

    • Author(s)
      Keiki Kumano, Shunya Arai, Koki Ueda, et al.
    • Organizer
      52^<nd> ASH Annual Meeting.
    • Place of Presentation
      Orland, Florida, USA.
    • Year and Date
      2010-12-04
    • Data Source
      KAKENHI-PROJECT-20591111
  • [Presentation] Kumano K, Masuda S, Sata M, et. al., Both Notch1 and Notch2 contribute to the regulation of melanocyte stem cells2006

    • Author(s)
      Kumano K, Masuda S, Sata M, et. al.
    • Organizer
      27th Annual meeting of Japanese Society of inflammation and regenerative medicine
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Presentation] Both Notch1 and Notch2 contribute to the regulation of melanocyte stem cells2006

    • Author(s)
      Kumano K, Masuda S, Sata M, et. al.
    • Organizer
      4th stem cell symposium
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Presentation] Kumano K, Masuda S, Sata M, et. al., Both Notch1 and Notch2 contribute to the regulation of melanocyte stem cells2006

    • Author(s)
      Kumano K, Masuda S, Sata M, et. al.
    • Organizer
      4th International Society for Stem Cell Research : 2006 Annual Meeting
    • Place of Presentation
      Toronto, Canada
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Presentation] Notch1およびNotch2による色素幹細胞の制御2006

    • Author(s)
      熊野恵城、増田茂夫, ら
    • Organizer
      第27回 日本炎症・再生医学会
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Presentation] Both Notch1 and Notch2 contribute to the regulation of melanocyte stem cells.2006

    • Author(s)
      Kumano K, Masuda S, Sata M, et. al.
    • Organizer
      4th International Society for Stem Cell Research: 2006 Annual Meeting
    • Place of Presentation
      Toronto, Canada
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Presentation] Notch1およびNotch2による色素幹細胞の制御2006

    • Author(s)
      熊野恵城、増田茂夫, ら
    • Organizer
      第4回幹細胞シンポジウム
    • Place of Presentation
      東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18591044
  • [Presentation] SNP chip analysis of myelodysplastic syndromes disclosed High Frequency of uniparental disomy and a novel dominant mutation as the target of 11qUPD

    • Author(s)
      Sanada M, Lee-Y., Shih L, Suzuki T, Yamamoto G, Nannya Y, Yanagimoto-Sakata M, Kato M, Kumano K, Kawamata N, Mori H, Kurokawa M, Chiba S, Omine M, Koeffler PH, S Ogawa
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390279
  • []

  • 1.  SUZUKI Takahiro (40345210)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 7 results
  • 2.  CHIBA Shigeru (60212049)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 6 results
  • 3.  HANGAISHI Akira (20344450)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 4.  OGAWA Seishi (60292900)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 17 results
  • 5.  YAMAMOTO Go (70396753)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 6.  SAKATA Mamiko (80451805)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  IZUTSU Koji (30361471)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  ASAI Takashi (10376436)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KAMIKUBO Yasuhiko (60548527)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 10.  NAKAGAWA Masahiro (10431850)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  増田 茂夫 (10396749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  北村 俊雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  北浦 次郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  安友 康二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  黒川 峰夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 16.  上野 愽夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  厚海 奈穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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