Matsuzaki Takashi 松崎高志

… Alternative Names

松崎高志マツザキタカシ

MATSUZAKI Takashi 松崎高志

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Researcher Number	90456939
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 特任教授(常勤)
Affiliation (based on the past Project Information) *help	2023: 大阪大学, 大学院医学系研究科, 特任准教授(常勤) 2018: 大阪大学, 医学系研究科, 特任講師(常勤) 2017: 香川大学, 医学部, 研究員 2016 – 2017: 大阪大学, 医学系研究科, 特任助教 2015: 大阪大学, 医学(系)研究科(研究院), 特任助教 … More 2011: 大阪大学, 医学研究科, 特任研究員 2011: 大阪大学, 医学系研究科, 特任助教 2010: Osaka University, 産業科学研究所, 特任助教(常勤) 2009: Osaka University, 産業科学研究所, 助教 Less
Review Section/Research Field	Principal Investigator General internal medicine and related fields / Biomedical engineering/Biomaterial science and engineering / Biomedical engineering/Biological material science Except Principal Investigator Basic Section 55030:Cardiovascular surgery-related / Cardiovascular medicine / Circulatory organs internal medicine / Biomedical engineering/Biological material science
Keywords	Principal Investigator drug delivery system / ナノリポソーム / 循環器内科学 / ガドリニウム / 劇症型心筋炎 / リポソーム / Gd / nAChR選択的アゴニスト / 診断と治療 / DDS … More / 心筋炎 / 遺伝子デリバリー / ADC / 抗体核酸複合体 / 心不全 / siRNA / 遺伝子治療 / 抗体薬物複合体 / 感染機構 / 膜融合ペプチド / HBV / ナノメディスン / ナノバイオロジー … More Except Principal Investigator ドラッグデリバリー / 体内動態 / 投与方法 / 心不全治療 / Lipid Nanoparticle / 虚血再灌流障害 / 治療法開発 / 心不全 / mRNA / 脂質ナノ粒子 / バイオテクノロジー / HB-EGF / 循環器・高血圧 / 不安定プラーク / 薬物送達 / HB-EGF抗体結合ベクター / HB-EGF抗体 / リポソーム / 治療 / 診断 / 劇症型心筋炎 / 劇症型心筋症 / 分子心臓病態学 / ペルオキシソーム / 細胞生物学 / タンパク質送達システム Less

心不全治療における核酸内包脂質ナノ粒子製剤の至適投与デバイス開発のための基礎研究
- Principal Investigator
  
  笹井雅夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Osaka University
Theranostic Development for myocarditis.Principal Investigator
- Principal Investigator
  
  Matsuzaki Takashi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  General internal medicine and related fields
- Research Institution
  Osaka University
Development of a novel antibody gene complex for the gene therapy of heart failure.Principal Investigator
- Principal Investigator
  
  MATSUZAKI Takashi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Osaka University
Development of antibody-drug conjugate to diagnose and treat vulnerable plaque
- Principal Investigator
  
  MINAMINO TETSUO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kagawa University
  Osaka University
Development of image diagnosis and treatment for fluminant myocarditis
- Principal Investigator
  
  MINAMINO Tetsuo
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka University
Development of a novel protein delivery system using peroxisomes
- Principal Investigator
  
  TANIZAWA Katsuyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka University
Analysis of the infection mechanism of human hepatitis B virus using bio-nanocapsule.Principal Investigator
- Principal Investigator
  
  MATSUZAKI Takashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka University

All 2018 2017 2016 2015 2012 2011 2010

All Journal Article Presentation Patent

[Journal Article] Anti-HB-EGF Antibody-Mediated Delivery of siRNA to Atherosclerotic Lesions in Mice2018
- Author(s)
  Shota Tsuchida, Takashi Matsuzaki, Masaki Yamato, Keiji Okuda, Hai Ying Fu, Ryo Araki, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, Hiroyuki Hao, Seiji Takashima, Masafumi Kitakaze, Yasushi Sakata, Eisuke Mekada, Tetsuo Minamino
- Journal Title
  
  Int. Heart J.
  
  Volume: 59 Issue: 6 Pages: 1425-1431
- DOI
  10.1536/ihj.17-644
- NAID
  130007522227
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2018-11-30
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19659, KAKENHI-PROJECT-18K19547
[Journal Article] RNA Aptamer Binds Heparin-Binding Epidermal Growth Factor-Like Growth Factor with High Affinity and Specificity and Neutralizes Its Activity2017
- Author(s)
  Masaki Yamato, Takashi Matsuzaki, Ryo Araki, Shota Tsuchida, Keiji Okuda, Hai Ying Fu, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, Hiroomi Torii, Kentaro Noi, Hirotsugu Ogi, Ryo Iwamoto, Eisuke Mekada, Seiji Takashima, Yasushi Sakata,
- Journal Title
  
  International Journal of Gerontology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12542
[Journal Article] Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats.2017
- Author(s)
  Okuda K, Fu HY, Matsuzaki T, Araki R, Tsuchida S, Thanikachalam PV, Fukuta T, Asai T, Yamato M, Sanada S, Asanuma H, Asano Y, Asakura M, Hanawa H, Hao H, Oku N, Takashima S, Kitakaze M, Sakata Y, Minamino T.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 8 Pages: e0160944-e0160944
- DOI
  10.1371/journal.pone.0160944
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04820, KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-14J10730, KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-16K08201, KAKENHI-PROJECT-15K12542
[Journal Article] Development of a novel one-step production system for injectable liposomes under GMP2017
- Author(s)
  Araki Ryo、Matsuzaki Takashi、Nakamura Ayumi、Nakatani Daisaku、Sanada Shoji、Fu Hai Ying、Okuda Keiji、Yamato Masaki、Tsuchida Shota、Sakata Yasushi、Minamino Tetsuo
- Journal Title
  
  Pharm Dev Technol.
  
  Volume: 10 Issue: 6 Pages: 1-6
- DOI
  10.1080/10837450.2017.1290106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04821, KAKENHI-PROJECT-15K12542
[Journal Article] A Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac Dysfunction.2016
- Author(s)
  Fu HY, Sanada S, Matsuzaki T, Liao Y, Okuda K, Yamato M, Tsuchida S, Araki R, Asano Y, Asanuma H, Asakura M, French BA, Sakata Y, Kitakaze M, Minamino T.
- Journal Title
  
  Circ Res.
  
  Volume: 118 Issue: 5 Pages: 798-809
- DOI
  10.1161/circresaha.115.307604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461134, KAKENHI-PROJECT-15K12542, KAKENHI-PROJECT-15H04821
[Journal Article] Nanocapsules Incorporating IgG Fc-binding Domain Derived from Staphylococcus aureus Protein-A for Displaying IgGs on Immunosensor Chips2011
- Author(s)
  M.Iijima, H.Kadoya, T.Matsuzaki, S.Hatahira, S.Hiramatsu, G.Jung, A.Martin, J.Quinn, J.Jung, S.-Y.Jeong, E.K.Choi, T.Arakawa, F.Hinako, M.Kusunoki, N.Yoshimoto, T.Niimi, K.Tanizawa, S.Kuroda
- Journal Title
  
  Biomaterials
  
  Volume: 32 Issue: 6 Pages: 1455-1464
- DOI
  10.1016/j.biomaterials.2010.10.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650111, KAKENHI-PROJECT-23710143
[Journal Article] Fluorophore-labeled nanocapsules displaying IgG Fc-binding domains for the simultaneous detection of multiple antigens2011
- Author(s)
  M.Iijima, T.Matsuzaki, N.Yoshimoto, T.Niimi, K.Tanizawa, S.Kuroda
- Journal Title
  
  Biomaterials
  
  Volume: 32 Issue: 34 Pages: 9011-9020
- DOI
  10.1016/j.biomaterials.2011.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650111, KAKENHI-PROJECT-23710143
[Patent] 炎症性疾患治療用医薬組成物2012
- Inventor(s)
  南野哲男、小室一成、松崎高志、奥直人、浅井知浩、富海英
- Industrial Property Rights Holder
  国立大学法人大阪大学、静岡県効率大学法人
- Industrial Property Number
  2012-117077
- Filing Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-23659416
[Presentation] ドラッグデリバリーシステムを用いた急性心筋梗塞治療薬の開発2016
- Author(s)
  南野哲男、松崎高志、中谷大作、荒木亮
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2016-05-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] ＤＤＳを用いた急性心筋梗塞治療薬の開発2016
- Author(s)
  南野哲男、松崎高志、中谷大作、荒木亮
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ（静岡県コンベンションアーツセンター）
- Year and Date
  2016-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] HB-EGF抗体を用いた動脈硬化巣への核酸デリバリーシステムの開発2016
- Author(s)
  松崎高志、土田翔太、富海英、奥田啓二、山戸昌樹、荒木亮、南野哲男
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ（静岡県コンベンションアーツセンター）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] 細胞内侵入抗体を用いた抗体RNA複合体の開発と循環器疾患への応用2016
- Author(s)
  松崎高志、土田翔太、南野哲男
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] リポソーム化免疫抑制剤による心筋炎治療2016
- Author(s)
  奥田啓二、松崎高志、富海英、土田翔太、荒木亮、山戸昌樹、福田達也、浅井智浩、奥直人、南野哲男
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  グランシップ（静岡県コンベンションアーツセンター）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] HB-EGF抗体を用いた不全心特異的核酸デリバリーシステムの開発2015
- Author(s)
  土田翔太、富海英、奥田敬二、山戸昌樹、荒木亮、真田昌繭、松崎高志、南野哲男
- Organizer
  第31回日本DDS学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] 急性心筋梗塞治療薬としてのリポソーム製剤の開発とアカデミア創薬2015
- Author(s)
  松崎高志、荒木亮、南野哲夫
- Organizer
  第31回日本DDS学会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2015-07-03
- Invited
- Data Source
  KAKENHI-PROJECT-15K12542
[Presentation] ヒトB型肝炎ウイルス表面抗原Lタンパク質における新規膜融合モチーフの同定と生化学的解析2010
- Author(s)
  土田翔太、松崎高志、谷澤克行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21700466
[Presentation] ヒトB型肝炎ウイルス帳面抗原Lタンパク質における新規膜融合モチーフの同定と生化学的解析2010
- Author(s)
  土田翔太、松崎高志、谷澤克行
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(口頭発表,ポスター)
- Data Source
  KAKENHI-PROJECT-21700466

1. 富海英 (70754646)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. MINAMINO Tetsuo (30379234)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. TANIZAWA Katsuyuki (20133134)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. SANADA Shoji (70593797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 眞鍋史乃 (60300901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 浅井知浩 (00381731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 村上和司 (60575207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 野間貴久 (20363202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 羽尾裕之 (40393243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 相楽郁恵 (40808474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 笹井雅夫 (70598680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 川村匡 (70583011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ASAKURA Masanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. TAKASHIMA Seiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. ASANO Yoshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 北風政史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 浅沼博司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsuzaki Takashi 松崎 高志

松崎 高志 マツザキ タカシ

MATSUZAKI Takashi 松崎 高志

Research Projects

Research Products

Co-Researchers

心不全治療における核酸内包脂質ナノ粒子製剤の至適投与デバイス開発のための基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Theranostic Development for myocarditis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel antibody gene complex for the gene therapy of heart failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of antibody-drug conjugate to diagnose and treat vulnerable plaque

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of image diagnosis and treatment for fluminant myocarditis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel protein delivery system using peroxisomes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the infection mechanism of human hepatitis B virus using bio-nanocapsule.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Anti-HB-EGF Antibody-Mediated Delivery of siRNA to Atherosclerotic Lesions in Mice2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] RNA Aptamer Binds Heparin-Binding Epidermal Growth Factor-Like Growth Factor with High Affinity and Specificity and Neutralizes Its Activity2017

Author(s)

Journal Title

Data Source

[Journal Article] Targeted Therapy for Acute Autoimmune Myocarditis with Nano-Sized Liposomal FK506 in Rats.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a novel one-step production system for injectable liposomes under GMP2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac Dysfunction.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanocapsules Incorporating IgG Fc-binding Domain Derived from Staphylococcus aureus Protein-A for Displaying IgGs on Immunosensor Chips2011

Author(s)

Journal Title

DOI

Matsuzaki Takashi 松崎高志

松崎高志マツザキタカシ

MATSUZAKI Takashi 松崎高志