TANAKA TETSUHIRO 田中哲洋

… Alternative Names

TANAKA Tetsuhiro 田中哲洋

Less

Researcher Number	90508079
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東北大学, 医学系研究科, 教授 2019 – 2023: 東京大学, 医学部附属病院, 准教授 2014 – 2018: 東京大学, 医学部附属病院, 講師 2014: 東京大学, 医学部附属病院, 病院講師 2012 – 2013: 東京大学, 医学部附属病院, 助教 … More 2009 – 2011: The University of Tokyo, 保健・健康推進本部, 助教 2009 – 2011: 東京大学, 保健健康推進本部, 助教 2008: The University of Tokyo, 医学部付属病院, 医員 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Basic Section 52010:General internal medicine-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 59040:Nutrition science and health science-related / Neo-Gerontology
Keywords	Principal Investigator 慢性腎臓病 / 低酸素 / HIF / プロリン水酸化酵素 / 低酸素誘導因子2 / 虚血再灌流障害 / AKI-CKD移行 / 低酸素誘導因子 / 糖尿病性腎臓病 / 肥満関連腎症 … More / PHD阻害薬 / 進行性腎疾患 / HIF-3 / 糖化修飾 / 心腎連関 … More Except Principal Investigator 慢性腎臓病 / 低酸素 / 小胞体ストレス / アポトーシス / 蛋白尿 / エネルギー代謝 / エピゲノム / HIF / 糸球体足細胞 / 腎不全 / CKD / ミトコンドリア / 脂質代謝 / オルガネラ間相互作用 / 尿細管炎症 / 一次繊毛 / オルガネラストレス / 尿細管細胞 / ATF6 / 線維化 / 低酸素応答 / 尿細管上皮細胞 / SASP / 細胞周期停止 / D-セリン / D-アミノ酸 / 近位尿細管上皮細胞 / 腎臓老化 / 細胞骨格 / エピジェネティクス / ヒストン修飾 / エピジェネティックス / 腎臓学 / 糖尿病生腎臓病 / 単一細胞解析 / ヒト初代培養細胞 / 糖尿病性腎臓病 / 細胞内代謝 / 認知機能障害 / サルコペニア / 高齢化社会 / 代謝 / 尿細管線炎症・維化 / 尿細管線維化 / 一次繊毛構成蛋白 / シスプラチン腎症 / 尿細管障害 / 尿細管細胞一次繊毛 / 尿細管炎症・線維化 / IRF88 / 糖尿病関連腎臓病 / オルガネラコンタクトサイト / 小胞体 / 一次繊毛 IRF88 / ヒストン / 尿細管間質 / 腎線維化 / 尿細管間質線維化 / 脂質毒性 / 急性腎不全 / cGAS-STING経路 / ミトコンドリアDNA / IFT88 / オルガネラクロストーク / 尿細管細胞代謝 / 尿細管脂質代謝 / ミトコンドリアストレス / 蛋白質恒常性 / 腎臓病態生理 / 尿細管間質障害 / 尿細管老化 / 尿細管 / podocyte / 医工連携 / organ on chip / マイクロデバイス / マクロファージ / 2-デオキシグルコース / 代謝リプログラミング / NF-κB / 尿細管間質傷害 / Mint3 / 解糖系 / 炎症 / metabolism / kidney / kidney fibrosis / Mitochondrial function / Fatty acid oxidation / Endoplasmic reticulum / UPR / Energy metabolism / Chronic kidney disease / エピジェネティック / ＨＩＦ / 酸化ストレス / microRNA 205 / microRNA / 尿毒素 / 糸球体腎炎 / アセチル化蛋白 / アクチン重合 / 糸球体濾過量 / アクチン細胞骨格 / cortactin / アセチル化 / SIRT1 / ポドサイト / 糖尿病性腎症 / 翻訳後修飾 / TGF-β1 / 高グルコース / オートファジー / 腎細胞癌 / 虚血再灌流モデル / グルコース / 分子シャペロン / 虚血 Less

尿毒素による細胞内代謝失調を標的とした高齢者の慢性腎臓病合併症の治療開発
- Principal Investigator
  
  佐藤恵美子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Tohoku University
Elucidation of renoprotective effects by pharmacological intervention into oxygen metabolism, using living renal cells from urine of diabetic kidney disease patients
- Principal Investigator
  
  鈴木教郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Tohoku University
Molecular mechanisms of kidney protection by hypoxia-inducible factor 2Principal Investigator
- Principal Investigator
  
  田中哲洋
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
Novel tubular homeostatic mechanism mediated by primary cilia
- Principal Investigator
  
  Inagi Reiko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
ヒストン修飾阻害薬GSKJ4による腎尿細管間質線維化の病態解明
- Principal Investigator
  
  三村維真理
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
Repair and regeneration of proximal tubular cells by inhibiting proxyl hydroxylasesPrincipal Investigator
- Principal Investigator
  
  Tanaka Tetsuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
  The University of Tokyo
Molecular mechanism of organelle crosstalk on organ homeostasis in aging and disease
- Principal Investigator
  
  Inagi Reiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  The University of Tokyo
Elucidation of metabolic reprogramming in the kidney and development of novel therapeutic approaches utilizing HIF against kidney disease
- Principal Investigator
  
  Nangaku Masaomi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  The University of Tokyo
Therapeutic intervention of CKD targeting cellular oxygen sensorsPrincipal Investigator
- Principal Investigator
  
  Tanaka Tetsuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Development of novel therapeutic approaches targeting ATF6-mediated metabolic alteration
- Principal Investigator
  
  饒梓明
- Project Period (FY)
  2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Development of Novel Therapy for Renal Diseases Targeting Macrophage Metabolic Reprogramming
- Principal Investigator
  
  Kawakami Takahisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kyorin University
  The University of Tokyo
Establishment of innovative culture system, kidney-on-chip, utilizing microdevice
- Principal Investigator
  
  Nangaku Masaomi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Pathophysiological role of D-amino acid on proteostasis in the kidney
- Principal Investigator
  
  Reiko Inagi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Mechanisms of maintenance of podocyte cytoskeletal structure against metabolic stress associated with diabetes and Development of novel therapeutic strategies
- Principal Investigator
  
  WADA Takehiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokai University
Epigenetic regulation of endoplasmic reticulum stress signal in aging of kidney
- Principal Investigator
  
  Inagi Reiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neo-Gerontology
- Research Institution
  The University of Tokyo
Metabolic Reprogramming and Hypoxic Memory in Kidney Disease
- Principal Investigator
  
  Nangaku Masaomi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Regulation of hypoxia inducible genes in chronic kidney diseasePrincipal Investigator
- Principal Investigator
  
  TANAKA Tetsuhiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Elucidation of the pathogenesis of kidney disease via epigenetic responses against hypoxia
- Principal Investigator
  
  NANGAKU Masaomi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Elucidation of the mechanisms of podocyte homeostasis and development of new therapeutic strategies against diabetic kidney disease
- Principal Investigator
  
  WADA Takehiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
a role of HIF-3 in adjusting cellular hypoxia response and its implications in progressive renal diseasePrincipal Investigator
- Principal Investigator
  
  TANAKA TETSUHIRO
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Elucidation of the pathophysiology of chronic kidney disease by comprehensive analysis of the hypoxia-responsive transcriptional network
- Principal Investigator
  
  NANGAKU Masaomi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Elucidation of the mechanisms underlying podocyte injury through endoplasmic reticulum stress and Development of novel therapeutic strategies for glomerular diseases
- Principal Investigator
  
  WADA Takehiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
A role of dysregulated glycosylation of hypoxia-inducible factors in the pathogenesis of cardio-renal syndromePrincipal Investigator
- Principal Investigator
  
  TANAKA Tetsuhiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

[Book] 腎機能低下時の薬剤ポケットマニュアル2015
- Author(s)
  南学正臣（編集）、和田健彦、加藤秀樹、田中哲洋他
- Total Pages
  380
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K09247
[Journal Article] Crosstalk between oxygen signaling and iron metabolism in renal interstitial fibroblasts2024
- Author(s)
  Suzuki Norio、Iwamura Yuma、Kato Koichiro、Ishioka Hirotaka、Konta Yusuke、Sato Koji、Uchida Nao、Koida Noa、Sekine Hiroki、Tanaka Tetsuhiro、Kumagai Naonori、Nakai Taku
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 74 Issue: 3 Pages: 179-184
- DOI
  10.3164/jcbn.24-8
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19396, KAKENHI-PROJECT-23K14450, KAKENHI-PROJECT-23KK0137, KAKENHI-PROJECT-23K07666, KAKENHI-PROJECT-20K17272, KAKENHI-PROJECT-23K21372
[Journal Article] Investigating the cut-off values of captopril challenge test for primary aldosteronism using the novel chemiluminescent enzyme immunoassay method: a retrospective cohort study.2024
- Author(s)
  Tezuka Y, Omata K, Ono Y, Kambara K, Kamada H, Oguro S, Yamazaki Y, Gomez-Sanchez CE, Ito A, Sasano H, Takase K, Tanaka T, Katagiri H, Satoh F.
- Journal Title
  
  Hypertens Res.
  
  Volume: Online ahead of print Issue: 5 Pages: 1362-1371
- DOI
  10.1038/s41440-024-01594-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07713
[Journal Article] Population characteristics and diagnosis rate of chronic kidney disease by eGFR and proteinuria in Japanese clinical practice: an observational database study.2024
- Author(s)
  Tanaka T, Maruyama S, Chishima N, Akiyama H, Shimamoto K, Inokuchi S, Yokota K, Ozaki A.
- Journal Title
  
  Sci Rep.
  
  Volume: 14 Issue: 1 Pages: 5172-5172
- DOI
  10.1038/s41598-024-55827-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07713
[Journal Article] Hypoxia‐inducible lncRNA MIR210HG promotes HIF1α expression by inhibiting miR‐93‐5p in renal tubular cells2023
- Author(s)
  Saigusa Hanako、Mimura Imari、Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 16 Pages: 4040-4056
- DOI
  10.1111/febs.16794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
[Journal Article] Urinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease2023
- Author(s)
  Oshita Toma、Watanabe Shun、Toyohara Takafumi、Kujirai Ryota、Kikuchi Koichi、Suzuki Takehiro、Suzuki Chitose、Matsumoto Yotaro、Wada Jun、Tomioka Yoshihisa、Tanaka Tetsuhiro、Abe Takaaki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 12508-12508
- DOI
  10.1038/s41598-023-39657-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06737, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-21K08270
[Journal Article] Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia2023
- Author(s)
  Yamazaki Tomotaka、Mimura Imari、Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Physiological Reports
  
  Volume: 11 Issue: 17
- DOI
  10.14814/phy2.15810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
[Journal Article] Usefulness of gallium-67 scintigraphy for evaluating the histopathological activity in interstitial nephritis.2023
- Author(s)
  Matsumura M, Okada A, Yokoyama H, Sekiguchi M, Shimizu A, Tanaka T, Nangaku M, Takano H.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 27 Issue: 3 Pages: 251-261
- DOI
  10.1007/s10157-022-02302-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Transvenous Radiofrequency Catheter Ablation for an Aldosterone-Producing Tumor of the Left Adrenal Gland: A First in Human Case Report.2023
- Author(s)
  Oguro S, Ota H, Yanagaki S, Kawabata M, Kamada H, Omata K, Tezuka Y, Ono Y, Morimoto R, Satoh F, Toyama H, Tanimoto K, Konno D, Yamauchi M, Niwa Y, Miyamoto H, Mori K, Tanaka T, Ishihata H, Takase K.
- Journal Title
  
  Cardiovasc Intervent Radiol.
  
  Volume: 46 Issue: 12 Pages: 1666-1673
- DOI
  10.1007/s00270-023-03584-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07713
[Journal Article] Phospholipase D4 as a signature of toll-like receptor 7 or 9 signaling is expressed on blastic T-bet+B cells in systemic lupus erythematosus.2023
- Author(s)
  Yasaka K, Yamazaki T, Sato H, Shirai T, Cho M, Ishida K, Ito K, Tanaka T, Ogasawara K, Harigae H, Ishii T, Fujii H.
- Journal Title
  
  Arthritis Res Ther.
  
  Volume: 25 Issue: 1 Pages: 200-200
- DOI
  10.1186/s13075-023-03186-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-21K08452, KAKENHI-PROJECT-21K08469
[Journal Article] Chromatin remodeling factor, INO80, inhibits PMAIP1 in renal tubular cells via exchange of histone variant H2A.Z. for H2A2023
- Author(s)
  Miura Rika、Mimura Imari、Saigusa Hanako、Yamazaki Tomotaka、Tanemoto Fumiaki、Kurata Yu、Sato Dai、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 13235-13235
- DOI
  10.1038/s41598-023-40540-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15223, KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-23K07713, KAKENHI-PROJECT-23K27615
[Journal Article] Enhanced podocyte differentiation and changing drug toxicity sensitivity through pressure-controlled mechanical filtration stress on a glomerulus-on-a-chip2023
- Author(s)
  Doi Kotaro、Kimura Hiroshi、Kim Soo Hyeon、Kaneda Shohei、Wada Takehiko、Tanaka Tetsuhiro、Shimizu Akira、Sano Takanori、Chikamori Masamichi、Shinohara Marie、Matsunaga Yukiko T.、Nangaku Masaomi、Fujii Teruo
- Journal Title
  
  Lab on a Chip
  
  Volume: 23 Issue: 3 Pages: 437-450
- DOI
  10.1039/d2lc00941b
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08321, KAKENHI-PROJECT-18H01849, KAKENHI-PROJECT-20K08626
[Journal Article] Future perspectives of anemia management in chronic kidney disease using hypoxia-inducible factor-prolyl hydroxylase inhibitors.2022
- Author(s)
  Sugahara M, Tanaka T, Nangaku M.
- Journal Title
  
  Pharmacol Ther.
  
  Volume: 239 Pages: 108272-108282
- DOI
  10.1016/j.pharmthera.2022.108272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-19K17731
[Journal Article] Effect of M2-like macrophages of the injured-kidney cortex on kidney cancer progression2022
- Author(s)
  Taisuke Ishii, Imari Mimura, Koji Nagaoka, Akihiro Naito, Takehito Sugasawa, Ryohei Kuroda, Daisuke Yamada, Yasuharu Kanki, Haruki Kume, Tetsuo Ushiku, Kazuhiro Kakimi, Tetsuhiro Tanaka, Masaomi Nangaku
- Journal Title
  
  Cell Death Discovery
  
  Volume: 5 Issue: 1 Pages: 480-480
- DOI
  10.1038/s41420-022-01255-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-20H03432, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-20K09161
[Journal Article] What’s New in the Molecular Mechanisms of Diabetic Kidney Disease: Recent Advances2022
- Author(s)
  Watanabe Kimio、Sato Emiko、Mishima Eikan、Miyazaki Mariko、Tanaka Tetsuhiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 1 Pages: 570-570
- DOI
  10.3390/ijms24010570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0363, KAKENHI-PROJECT-20K08626
[Journal Article] Is HIF activation Janus faced? The therapeutic effects of the HIF-2α inhibitor2022
- Author(s)
  Ishii Taisuke、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Kidney International
  
  Volume: ahead of print Issue: 5 Pages: 866-869
- DOI
  10.1016/j.kint.2022.01.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Exploring molecular targets in diabetic kidney disease2022
- Author(s)
  Maruno Sayako、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Kidney Research and Clinical Practice
  
  Volume: ahead of print Issue: Suppl 2 Pages: S33-S45
- DOI
  10.23876/j.krcp.21.251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Bone marrow stromal cell antigen-1 (CD157) regulated by sphingosine kinase 2 mediates kidney fibrosis2022
- Author(s)
  Inoue T, Nakamura Y, Tanaka S, Kohro T, Li LX, Huang L, Yao J, Kawamura S, Inoue R, Nishi H, Fukaya D, Uni R, Hasegawa S, Inagi R, Umene R, Wu CH, Ye H, Bajwa A, Rosin DL, Ishihara K, Nangaku M, Wada Y, Okusa MD
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 9 Pages: 993698-993698
- DOI
  10.3389/fmed.2022.993698
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08222, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-20KK0174, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-23K24350
[Journal Article] Activation of α7 nicotinic acetylcholine receptors attenuates monocyte endothelial adhesion through FUT7 inhibition2022
- Author(s)
  Wu Chia-Hsien、Inoue Tsuyoshi、Nakamura Yasuna、Uni Rie、Hasegawa Sho、Maekawa Hiroshi、Sugahara Mai、Wada Youichiro、Tanaka Tetsuhiro、Nangaku Masaomi、Inagi Reiko
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 590 Pages: 89-96
- DOI
  10.1016/j.bbrc.2021.12.094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17242, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439, KAKENHI-PROJECT-21K16159, KAKENHI-PROJECT-21K20874, KAKENHI-PROJECT-22K16107
[Journal Article] A novel method for successful induction of interdigitating process formation in conditionally immortalized podocytes from mice, rats, and humans2021
- Author(s)
  Doi Kotaro、Kimura Hiroshi、Wada Takehiko、Tanaka Tetsuhiro、Hiromura Keiju、Saleem Moin A.、Inagi Reiko、Nangaku Masaomi、Fujii Teruo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 570 Pages: 47-52
- DOI
  10.1016/j.bbrc.2021.07.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H01849, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439
[Journal Article] Update on diagnosis, pathophysiology, and management of diabetic kidney disease2021
- Author(s)
  Sugahara Mai、Pak Wai Lun Will、Tanaka Tetsuhiro、Tang Sydney C. W.、Nangaku Masaomi
- Journal Title
  
  Nephrology
  
  Volume: 26 Issue: 6 Pages: 491-500
- DOI
  10.1111/nep.13860
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17731, KAKENHI-PROJECT-20K08626
[Journal Article] An evaluation of roxadustat for the treatment of anemia associated with chronic kidney disease2021
- Author(s)
  Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Expert Opinion on Pharmacotherapy
  
  Volume: 23 Issue: 1 Pages: 19-28
- DOI
  10.1080/14656566.2021.1993821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Profile of Daprodustat in the Treatment of Renal Anemia Due to Chronic Kidney Disease2021
- Author(s)
  Ishii T, Tanaka T, Nangaku M
- Journal Title
  
  Ther Clin Risk Manag
  
  Volume: 17 Pages: 155-163
- DOI
  10.2147/tcrm.s293879
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] TRPM2 Plays a Minor Role in AKI and Kidney Fibrosis2021
- Author(s)
  Kurata Yu、Tanaka Tetsuhiro、Cernecka Hana、Eitner Frank、Nangaku Masaomi
- Journal Title
  
  Kidney360
  
  Volume: 3 Issue: 1 Pages: 153-157
- DOI
  10.34067/kid.0005492021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] A distinctive distribution of hypoxia-inducible factor-1α in cultured renal tubular cells with hypoperfusion simulated by coverslip placement2021
- Author(s)
  Honda T, Hirakawa Y, Mizukami K, Yoshihara T, Tanaka T, Tobita S, Nangaku M
- Journal Title
  
  Physiol Rep
  
  Volume: 9 Issue: 1
- DOI
  10.14814/phy2.14689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H03509, KAKENHI-PROJECT-19K22947, KAKENHI-PROJECT-19K17697
[Journal Article] Metabolic Changes and Oxidative Stress in Diabetic Kidney Disease2021
- Author(s)
  Sakashita Midori、Tanaka Tetsuhiro、Inagi Reiko
- Journal Title
  
  Antioxidants
  
  Volume: 10 Issue: 7 Pages: 1143-1143
- DOI
  10.3390/antiox10071143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439
[Journal Article] β2-adrenergic receptor agonist counteracts skeletal muscle atrophy and oxidative stress in uremic mice2021
- Author(s)
  Takaaki Higashihara、Hiroshi Nishi、Koji Takemura、Hiroshi Watanabe、Toru Maruyama、Reiko Inagi、Tetsuhiro Tanaka、Masaomi Nangaku
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 9130-9130
- DOI
  10.1038/s41598-021-88438-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08232, KAKENHI-PROJECT-21H02824, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21K19439
[Journal Article] Treatment of Diabetic Kidney Disease: Current and Future2021
- Author(s)
  Tomotaka Yamazaki, Imari Mimura, Tetsuhiro Tanaka, Masaomi Nangaku
- Journal Title
  
  Diabetes Metab J
  
  Volume: 1 Issue: 1 Pages: 11-26
- DOI
  10.4093/dmj.2020.0217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08604, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-21J10424
[Journal Article] Adaptive Response as a Potential Key Link Between SGLT2 Inhibition and Renoprotection2021
- Author(s)
  Sasako Takayoshi、Tanaka Tetsuhiro、Yamauchi Toshimasa
- Journal Title
  
  Kidney International Reports
  
  Volume: 6 Issue: 8 Pages: 2022-2024
- DOI
  10.1016/j.ekir.2021.05.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Multiple consequences of HIF activation in CKD2020
- Author(s)
  Tanaka T
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 155 Issue: 1 Pages: 30-34
- DOI
  10.1254/fpj.19113
- NAID
  130007778964
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Modulating the immune system to delay the clinical onset of type 1 diabetes.2020
- Author(s)
  Sugahara M, Tanaka T, Nangaku M.
- Journal Title
  
  Kidney Int.
  
  Volume: 97 Issue: 2 Pages: 248-250
- DOI
  10.1016/j.kint.2019.10.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Nuclear factor erythroid 2-related factor 2 as a treatment target of kidney diseases2020
- Author(s)
  Ito Marie、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Current Opinion in Nephrology and Hypertension
  
  Volume: 29 Issue: 1 Pages: 128-135
- DOI
  10.1097/mnh.0000000000000556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626
[Journal Article] Prolyl hydroxylase inhibition protects the kidneys from ischemia via upregulation of glycogen storage.2020
- Author(s)
  Ito M, Tanaka T, Ishii T, Wakashima T, Fukui K, Nangaku M.
- Journal Title
  
  Kidney Int.
  
  Volume: 97 Issue: 4 Pages: 687-701
- DOI
  10.1016/j.kint.2019.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02824
[Journal Article] JTZ-951, an HIF prolyl hydroxylase inhibitor, suppresses renal interstitial fibroblast transformation and expression of fibrosis-related factors.2020
- Author(s)
  Wakashima T, Tanaka T, Fukui K, Komoda Y, Shinozaki Y, Kobayashi H, Matsuo A, Nangaku M.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 318 Issue: 1 Pages: F14-F24
- DOI
  10.1152/ajprenal.00323.2019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18H02824
[Journal Article] Effects of a prolyl hydroxylase inhibitor on kidney and cardiovascular complications in a rat model of chronic kidney disease.2020
- Author(s)
  Uchida L, Tanaka T, Saito H, Sugahara M, Wakashima T, Fukui K, Nangaku M.
- Journal Title
  
  Am J Physiol Renal Physiol.
  
  Volume: 318 Issue: 2 Pages: F388-F401
- DOI
  10.1152/ajprenal.00419.2019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02824
[Journal Article] Conditions, pathogenesis, and progression of diabetic kidney disease and early decliner in Japan2020
- Author(s)
  Yoshida Y, Kashiwabara K, Hirakawa Y, Tanaka T, Noso S, Ikegami H, Ohsugi M, Ueki K, Mita T, Watada H, Koya D, Mise K, Wada J, Shimizu M, Wada T, Ito Y, Narita I, Kashihara N, Nangaku M, Matsuyama Y
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 8 Issue: 1 Pages: 1-8
- DOI
  10.1136/bmjdrc-2019-000902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08530, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K09852, KAKENHI-PROJECT-20K08626
[Journal Article] Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice2020
- Author(s)
  Mai Sugahara、Shinji Tanaka、Tetsuhiro Tanaka、Hisako Saito、Yu Ishimoto、Takeshi Wakashima、Masatoshi Ueda、Kenji Fukui、Akira Shimizu、Reiko Inagi、Toshimasa Yamauchi、Takashi Kadowaki、Masaomi Nangaku
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 31 Issue: 3 Pages: 560-577
- DOI
  10.1681/asn.2019060582
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17731, KAKENHI-PROJECT-18H04053, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
[Journal Article] The role of hypoxia in the pathogenesis of lupus nephritis2020
- Author(s)
  Kurata Y, Tanaka T, Nangaku M
- Journal Title
  
  Kidney Int
  
  Volume: 98 Issue: 4 Pages: 821-823
- DOI
  10.1016/j.kint.2020.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] New insights into tubular cell recovery after ischemic acute kidney injury2020
- Author(s)
  Sakashita M, Tanaka T, Nangaku M
- Journal Title
  
  Kidney Int
  
  Volume: 97 Issue: 5 Pages: 845-846
- DOI
  10.1016/j.kint.2020.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626
[Journal Article] Hypoxia-inducible factor prolyl hydroxylase inhibitor in the treatment of anemia in chronic kidney disease2020
- Author(s)
  Kurata Y, Tanaka T, Nangaku M
- Journal Title
  
  Curr Opin Nephrol Hypertens
  
  Volume: 29 Issue: 4 Pages: 414-422
- DOI
  10.1097/mnh.0000000000000617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08626, KAKENHI-PROJECT-18H02824
[Journal Article] Regulatory roles of hypoxia-inducible, noncoding RNAs on mitochondrial dynamics during AKI2019
- Author(s)
  Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Kidney International
  
  Volume: 95 Issue: 2 Pages: 252-253
- DOI
  10.1016/j.kint.2018.12.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Hypoxia-Inducible Factor-Prolyl Hydroxylase Domain Inhibitors to Treat Anemia in Chronic Kidney Disease2019
- Author(s)
  Sakashita Midori、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Contributions to Nephrology
  
  Volume: 198 Pages: 112-123
- DOI
  10.1159/000496531
- ISBN
  9783318064230, 9783318064247
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
[Journal Article] JTZ-951 (enarodustat), a hypoxia-inducibe factor prolyl hydroxylase inhibitor, stabilizes HIF-α protein and induces erythropoiesis without effects on the function of vascular endothelial growth factor2019
- Author(s)
  Fukui Kenji、Shinozaki Yuichi、Kobayashi Hatsue、Deai Katsuya、Yoshiuchi Hiromi、Matsui Takuya、Matsuo Akira、Matsushita Mutsuyoshi、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 859 Pages: 172532-172532
- DOI
  10.1016/j.ejphar.2019.172532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
[Journal Article] Mitochondrial damage causes inflammation via cGAS-STING signaling in acute kidney injury2019
- Author(s)
  Hiroshi Maekawa, Tsuyoshi Inoue, haruki Ouchi, Tzu-Ming Jao, Reiko Inoue, Hiroshi Nishi, Rie Fujii, Fumiyoshi Ishidate, Tetsuhiro Tanaka, Yosuke Tanaka, Nobutaka Hirokawa, Masaomi Nangaku, Reiko Inagi
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 5 Pages: 1261-1273
- DOI
  10.1016/j.celrep.2019.09.050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08232, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-19K21297
[Journal Article] Non-canonical cholinergic anti-inflammatory pathway-mediated activation of peritoneal macrophages induces Hes1 and blocks ischemia/ reperfusion injury in the kidney.2019
- Author(s)
  Inoue T,Abe C, Kohro T, Tanaka S, Huang L, Yao J, Zheng S, Ye H, Inagi R, Stornetta RL, Rosin DL, Nangaku M, Wada Y, Okusa MD
- Journal Title
  
  Kidney International
  
  Volume: 95(3) Issue: 3 Pages: 563-576
- DOI
  10.1016/j.kint.2018.09.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19K21297, KAKENHI-ORGANIZER-15H05935
[Journal Article] Comprehensive three-dimensional analysis (CUBIC-kidney) visualizes abnormal renal sympathetic nerves after ischemia/reperfusion injury.2019
- Author(s)
  Hasegawa S, Susaki EA, Tanaka T, Komaba H, Wada T, Fukagawa M, Ueda HR, Nangaku M
- Journal Title
  
  Kidney international
  
  Volume: AOP Issue: 1 Pages: 129-138
- DOI
  10.1016/j.kint.2019.02.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05650, KAKENHI-PROJECT-18K08254, KAKENHI-PLANNED-17H06328, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19H03413, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18K19419
[Journal Article] Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet2019
- Author(s)
  Saito Hisako、Tanaka Tetsuhiro、Sugahara Mai、Tanaka Shinji、Fukui Kenji、Wakashima Takeshi、Nangaku Masaomi
- Journal Title
  
  Laboratory Investigation
  
  Volume: 99 Issue: 8 Pages: 1217-1232
- DOI
  10.1038/s41374-019-0239-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
[Journal Article] Regional variance in patterns of prescriptions for chronic kidney disease in Japan2019
- Author(s)
  Inoue Reiko、Nishi Hiroshi、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 印刷中 Issue: 6 Pages: 859-864
- DOI
  10.1007/s10157-019-01720-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18K08232
[Journal Article] The oral hypoxia-inducible factor prolyl hydroxylase inhibitor enarodustat counteracts alterations in renal energy metabolism in the early stages of diabetic kidney disease2019
- Author(s)
  Hasegawa Sho、Tanaka Tetsuhiro、Saito Tomoyuki、Fukui Kenji、Wakashima Takeshi、Susaki Etsuo A.、Ueda Hiroki R.、Nangaku Masaomi
- Journal Title
  
  Kidney International
  
  Volume: in press Issue: 5 Pages: 934-950
- DOI
  10.1016/j.kint.2019.12.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19J11928, KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-20K08626, KAKENHI-PLANNED-17H06328, KAKENHI-PROJECT-19H03413
[Journal Article] Recent advances in renal regeneration2019
- Author(s)
  Hasegawa Sho、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  F1000Research
  
  Volume: 8 Pages: 216-216
- DOI
  10.12688/f1000research.17127.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Prolyl hydroxylase domain inhibitors: a new era in the management of renal anemia2019
- Author(s)
  Kurata Yu、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Annals of Translational Medicine
  
  Volume: 7 Issue: S8 Pages: S334-S334
- DOI
  10.21037/atm.2019.09.118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17K09688
[Journal Article] ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis2019
- Author(s)
  Jao Tzu-Ming、Nangaku Masaomi、Wu Chia-Hsien、Sugahara Mai、Saito Hisako、Maekawa Hiroshi、Ishimoto Yu、Aoe Mari、Inoue Tsuyoshi、Tanaka Tetsuhiro、Staels Bart、Mori Kazutoshi、Inagi Reiko
- Journal Title
  
  Kidney International
  
  Volume: 95 Issue: 3 Pages: 577-589
- DOI
  10.1016/j.kint.2018.09.023
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-19K21297, KAKENHI-PROJECT-17H01432
[Journal Article] HIF Activation Against CVD in CKD: Novel Treatment Opportunities2018
- Author(s)
  Tanaka Tetsuhiro、Eckardt Kai-Uwe
- Journal Title
  
  Seminars in Nephrology
  
  Volume: 38 Issue: 3 Pages: 267-276
- DOI
  10.1016/j.semnephrol.2018.02.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Hypoxia-inducible factor stabilizers for treating anemia of chronic kidney disease2018
- Author(s)
  Hasegawa Sho、Tanaka Tetsuhiro、Nangaku Masaomi
- Journal Title
  
  Current Opinion in Nephrology and Hypertension
  
  Volume: 27 Issue: 5 Pages: 331-338
- DOI
  10.1097/mnh.0000000000000431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824
[Journal Article] Palmitate deranges erythropoietin production via ATF4 activation of unfolded protein response2018
- Author(s)
  Thitinun Anusornvongchai, Masaomi Nangaku, Tzu-Ming Jao, Chia-Hsien Wu, Yu Ishimoto, Hiroshi Maekawa, Tetsuhiro Tanaka, Akira Shimizu, Masayuki Yamamoto, Norio Suzuki, Ryoji Sassa, and Reiko Inagi
- Journal Title
  
  Kidney Int.
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15KT0088
[Journal Article] Genome-wide analysis revealed that DZNep reduces tubulointerstitial fibrosis via down-regulation of pro-fibrotic genes.2018
- Author(s)
  Mimura I, Hirakawa Y, Kanki Y, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M.
- Journal Title
  
  Sci Rep.
  
  Volume: 28 Issue: 1 Pages: 3779-3779
- DOI
  10.1038/s41598-018-22180-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-16K15438, KAKENHI-PROJECT-16K19477, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-15KK0251, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-16H06279
[Journal Article] Physiological and pathophysiological role of reactive oxygen species and reactive nitrogen species in the kidney2018
- Author(s)
  Ishimoto Yu、Tanaka Tetsuhiro、Yoshida Yoko、Inagi Reiko
- Journal Title
  
  Clinical and Experimental Pharmacology and Physiology
  
  Volume: 45 Issue: 11 Pages: 1097-1105
- DOI
  10.1111/1440-1681.13018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-18H02727
[Journal Article] Persistent expression of neutrophil gelatinase-associated lipocalin and M2 macrophage markers and chronic fibrosis after acute kidney injury2018
- Author(s)
  Saito Hisako、Tanaka Tetsuhiro、Tanaka Shinji、Higashijima Yoshiki、Yamaguchi Junna、Sugahara Mai、Ito Marie、Uchida Lisa、Hasegawa Sho、Wakashima Takeshi、Fukui Kenji、Nangaku Masaomi
- Journal Title
  
  Physiological Reports
  
  Volume: 6 Issue: 10 Pages: e13707-e13707
- DOI
  10.14814/phy2.13707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K15991, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17J07088
[Journal Article] Palmitate deranges erythropoietin production via ATF4 activation of unfolded protein response2018
- Author(s)
  Thitinun Anusornvongchai, Masaomi Nangaku, Tzu-Ming Jao, Chia-Hsien Wu, Yu Ishimoto, Hiroshi Maekawa, Tetsuhiro Tanaka, Akira Shimizu, Masayuki Yamamoto, Norio Suzuki, Ryoji Sassa, and Reiko Inagi
- Journal Title
  
  Kidney Int.
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15465
[Journal Article] Sodium glucose cotransporter 2 inhibition normalizes glucose metabolism and suppresses oxidative stress in the kidneys of diabetic mice2018
- Author(s)
  Tanaka Shinji、Sugiura Yuki、Saito Hisako、Sugahara Mai、Higashijima Yoshiki、Yamaguchi Junna、Inagi Reiko、Suematsu Makoto、Nangaku Masaomi、Tanaka Tetsuhiro
- Journal Title
  
  Kidney International
  
  Volume: 94 Issue: 5 Pages: 912-925
- DOI
  10.1016/j.kint.2018.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K15991, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-17J07088
[Journal Article] Intravital phosphorescence lifetime imaging of the renal cortex accurately measures renal hypoxia.2018
- Author(s)
  Hirakawa Y, Mizukami K, Yoshihara T, Takahashi I, Khulan P, Honda T, Mimura I, Tanaka T, Tobita S, Nangaku M.
- Journal Title
  
  Kidney Int.
  
  Volume: 印刷中 Issue: 6 Pages: 1483-1489
- DOI
  10.1016/j.kint.2018.01.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K16070, KAKENHI-PROJECT-16K19477, KAKENHI-PLANNED-26111003, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-17H02078, KAKENHI-PROJECT-18H02824, KAKENHI-PROJECT-18H03509
[Journal Article] Guidelines for clinical evaluation of chronic kidney disease2018
- Author(s)
  Kanda Eiichiro、Research Working Group for Establishing Guidelines for Clinical Evaluation of Chronic Kidney Disease、Kashihara Naoki、Matsushita Kunihiro、Usui Tomoko、Okada Hirokazu、Iseki Kunitoshi、Mikami Kenichi、Tanaka Tetsuhiro、Wada Takashi、Watada Hirotaka、Ueki Kohjiro、Nangaku Masaomi
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 22 Issue: 6 Pages: 1446-1475
- DOI
  10.1007/s10157-018-1615-x
- NAID
  120006557512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response2018
- Author(s)
  Anusornvongchai Thitinun、Nangaku Masaomi、Jao Tzu-Ming、Wu Chia-Hsien、Ishimoto Yu、Maekawa Hiroshi、Tanaka Tetsuhiro、Shimizu Akira、Yamamoto Masayuki、Suzuki Norio、Sassa Ryoji、Inagi Reiko
- Journal Title
  
  Kidney International
  
  Volume: 94 Issue: 3 Pages: 536-550
- DOI
  10.1016/j.kint.2018.03.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K19680, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
[Journal Article] The Anticipated Renoprotective Effects of Sodium-glucose Cotransporter 2 Inhibitors2018
- Author(s)
  Ito M, Tanaka T.
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 15 Pages: 2105-2114
- DOI
  10.2169/internalmedicine.9842-17
- NAID
  130007429844
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-08-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Safety and effectiveness of long-term use of darbepoetin alfa in non-dialysis patients with chronic kidney disease: a post-marketing surveillance study in Japan2018
- Author(s)
  Tanaka Tetsuhiro、Nangaku Masaomi、Imai Enyu、Tsubakihara Yoshiharu、Kamai Masatoshi、Wada Michihito、Asada Shinji、Akizawa Tadao
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 23 Issue: 2 Pages: 231-243
- DOI
  10.1007/s10157-018-1632-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] Echinomycin inhibits adipogenesis in 3T3-L1 cells in a HIF-independent manner.2017
- Author(s)
  Yamaguchi J, Tanaka T, Saito H, Nomura S, Aburatani H, Waki H, Kadowaki T, Nangaku M.
- Journal Title
  
  Sci Rep.
  
  Volume: 26 Issue: 1 Pages: 6516-6516
- DOI
  10.1038/s41598-017-06761-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835
[Journal Article] Vascular adhesion protein-1 enhances neutrophil infiltration by generation of hydrogen peroxide in renal ischemia/reperfusion injury.2017
- Author(s)
  Tanaka S, Tanaka T, Kawakami T, Takano H, Sugahara M, Saito H, Higashijima Y, Yamaguchi J, Inagi R, Nangaku M.
- Journal Title
  
  Kidney Int
  
  Volume: 印刷中 Issue: 1 Pages: 154-164
- DOI
  10.1016/j.kint.2017.01.014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465, KAKENHI-PROJECT-17K15991, KAKENHI-PROJECT-17J07088, KAKENHI-PROJECT-15K09247
[Journal Article] Effect of AST-120 in Chronic Kidney Disease Treatment: Still a Controversy?2017
- Author(s)
  Yamaguchi J, Tanaka T, Inagi R.
- Journal Title
  
  Nephron
  
  Volume: １３５ Issue: 3 Pages: 201-206
- DOI
  10.1159/000453673
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
[Journal Article] Renal Hypoxia in CKD; Pathophysiology and Detecting Methods.2017
- Author(s)
  Hirakawa Y, Tanaka T, Nangaku M.
- Journal Title
  
  Front Physiol
  
  Volume: 8 Pages: 99-99
- DOI
  10.3389/fphys.2017.00099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-17K16070, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K09247
[Journal Article] Renal Hypoxia in CKD; Pathophysiology and Detecting Methods2017
- Author(s)
  Hirakawa Y, Tanaka T, Nangaku M
- Journal Title
  
  Front Physiol
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09247
[Journal Article] Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease.2017
- Author(s)
  Sugahara M, Tanaka T, Nangaku M.
- Journal Title
  
  Kidney Int.
  
  Volume: 92 Issue: 2 Pages: 306-312
- DOI
  10.1016/j.kint.2017.02.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-15K09247
[Journal Article] Epigenetic Changes in the Acute Kidney Injury-to-Chronic Kidney Disease Transition.2017
- Author(s)
  Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
- Journal Title
  
  Nephron.
  
  Volume: 137 Issue: 4 Pages: 256-259
- DOI
  10.1159/000476078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-16K15465
[Journal Article] Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease.2017
- Author(s)
  Hirakawa Y, Tanaka T, Nangaku M.
- Journal Title
  
  J Diabetes Investig.
  
  Volume: - Issue: 3 Pages: 261-271
- DOI
  10.1111/jdi.12624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461215, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15K09247
[Journal Article] Vascular adhesion protein-1 enhances neutrophil infiltration by generation of hydrogen peroxide in renal ischemia/reperfusion injury2017
- Author(s)
  Tanaka S, Tanaka T, Kawakami T, Takano H, Sugahara M, Saito H, Higashijima Y, Yamaguchi J, Inagi R, Nangaku M
- Journal Title
  
  Kidney Int
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09247
[Journal Article] PHD in the FOXD1 lineage cells links hypoxia to inappropriate nephrogenesis.2017
- Author(s)
  Tanaka T.
- Journal Title
  
  Kidney Int.
  
  Volume: 92 Issue: 6 Pages: 1314-1316
- DOI
  10.1016/j.kint.2017.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09688
[Journal Article] A mechanistic link between renal ischemia and fibrosis.2017
- Author(s)
  Tanaka T.
- Journal Title
  
  Med Mol Morphol
  
  Volume: ５０ Issue: 1 Pages: 1-8
- DOI
  10.1007/s00795-016-0146-3
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] Novel lnc RNA regulated by HIF-1 inhibits apoptotic cell death in the renal tubular epithelial cells under hypoxia.2017
- Author(s)
  Mimura I, Hirakawa Y, Kanki Y, Kushida N, Nakaki R, Suzuki Y, Tanaka T, Aburatani H, Nangaku M.
- Journal Title
  
  Physiol Rep.
  
  Volume: 5 Issue: 8 Pages: e13203-e13203
- DOI
  10.14814/phy2.13203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-16K15438, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-17H03614, KAKENHI-PROJECT-15KK0251
[Journal Article] Expanding roles of the hypoxia-response network in chronic kidney2016
- Author(s)
  Tanaka T.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: Feb 9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] New insights into molecular mechanisms of epigenetic regulation in kidney disease.2016
- Author(s)
  Mimura I, Tanaka T, Nangaku M.
- Journal Title
  
  Clin Exp Pharmacol Physiol
  
  Volume: 43 Issue: 12 Pages: 1159-1167
- DOI
  10.1111/1440-1681.12663
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04835, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247
[Journal Article] Upregulation of α3β1-Integrin in Podocytes in Early-Stage Diabetic Nephropathy.2016
- Author(s)
  Sawada K, Toyoda M, Kaneyama N, Shiraiwa S, Moriya H, Miyatake H, Tanaka E, Yamamoto N, Miyauchi M, Kimura M, Wada T, Fukagawa M.
- Journal Title
  
  J Diabetes Res
  
  Volume: 2016 Pages: 9265074-9265074
- DOI
  10.1155/2016/9265074
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09247
[Journal Article] Expanding roles of the hypoxia-response network in chronic kidney disease.2016
- Author(s)
  Tanaka T
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: ２０ Pages: 835-844
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] The authors reply2015
- Author(s)
  Higashijima Y, Tanaka T, Nangaku M.
- Journal Title
  
  Kidney Int.
  
  Volume: 87 Issue: 3 Pages: 661-661
- DOI
  10.1038/ki.2014.410
- Data Source
  KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-14J03553
[Journal Article] Therapeutic approaches targeting fibrosis and hypoxia in the kidney2015
- Author(s)
  Tanaka T, Nangaku M.
- Journal Title
  
  Nihon Jinzo Gakkai Shi.
  
  Volume: 57 Pages: 1215-1224
- NAID
  40020642451
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] How to Supplement Iron in Patients with Renal Anemia.2015
- Author(s)
  Tanaka S, Tanaka T.
- Journal Title
  
  Nephron.
  
  Volume: 131 Issue: 2 Pages: 138-144
- DOI
  10.1159/000440773
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?2015
- Author(s)
  Nangaku M, Inagi R, Mimura I, Tanaka T
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] Anti-inflammatory role of DPP-4 inhibitors in a non-diabetic model of glomerular injury2015
- Author(s)
  Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: ahead of print Issue: 8 Pages: F878-F887
- DOI
  10.1152/ajprenal.00590.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J03553, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15H04835
[Journal Article] Epigenetic Changes Induced by Hypoxia-Inducible Factor: a Long Way Still To Go as a Target for Therapy?2015
- Author(s)
  Nangaku M, Inagi R, Mimura I, Tanaka T
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 26 Issue: 7 Pages: 1478-80
- DOI
  10.1681/asn.2014121161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15KT0088, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-25461207
[Journal Article] How the Target Hemoglobin of Renal Anemia Should Be2015
- Author(s)
  Mimura I, Tanaka T, Nangaku M
- Journal Title
  
  Nephron
  
  Volume: 131 Issue: 3 Pages: 202-9
- DOI
  10.1159/000440849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-26860627
[Journal Article] Anti-inflammatory role of DPP-4 inhibitors in a nondiabetic model of glomerular injury.2015
- Author(s)
  Higashijima Y, Tanaka T, Yamaguchi J, Tanaka S, Nangaku M.
- Journal Title
  
  American Journal of Physiology Renal Physiology
  
  Volume: 308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591189
[Journal Article] Recent advances in understanding of chronic kidney disease2015
- Author(s)
  Yamaguchi J, Tanaka T, Nangaku M
- Journal Title
  
  F1000Res
  
  Volume: 4 Pages: 1212-1212
- DOI
  10.12688/f1000research.6970.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-26461215
[Journal Article] Role of Uremic Toxins in Erythropoiesis-Stimulating Agent Resistance in Chronic Kidney Disease and Dialysis Patients.2015
- Author(s)
  Nangaku M, Mimura I, Yamaguchi J, Higashijima Y, Wada T, Tanaka T.
- Journal Title
  
  Journal of Renal Nutrition
  
  Volume: 25 Issue: 2 Pages: 160-163
- DOI
  10.1053/j.jrn.2014.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-14J03553, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-26860627, KAKENHI-PROJECT-15K09247
[Journal Article] Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ2015
- Author(s)
  Yamaguchi J, Tanaka T, Eto N, Nangaku M.
- Journal Title
  
  Kidney International
  
  Volume: 印刷中 Issue: 2 Pages: 262-75
- DOI
  10.1038/ki.2015.21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591189, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-26461215, KAKENHI-PROJECT-15K09247, KAKENHI-PROJECT-15H04835
[Journal Article] Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein δ..2015
- Author(s)
  Yamaguchi J, Tanaka T, Eto N, Nangaku M.
- Journal Title
  
  Kidney Int
  
  Volume: x
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390213
[Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes.2014
- Author(s)
  Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M.
- Journal Title
  
  Kidney Int
  
  Volume: Suppl 4 Pages: 107-112
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390213
[Journal Article] Role of hypoxia in progressive chronic kidney disease and implications for therapy2014
- Author(s)
  Shoji K, Tanaka T, Nangaku M
- Journal Title
  
  Curr Opin Nephrol Hypertens
  
  Volume: 23(2) Pages: 161-8
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] ANO1: an additional key player in cyst growth.2014
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Kidney International
  
  Volume: 85 Issue: 5 Pages: 1007-9
- DOI
  10.1038/ki.2013.436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215
[Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes.2014
- Author(s)
  Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M.
- Journal Title
  
  Kidney International Supplement
  
  Volume: 4 Pages: 107-112
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591189
[Journal Article] Role of hypoxia in progressive chronic kidney disease and implications for therapy.2014
- Author(s)
  Shoji K, Tanaka T, Nangaku M.
- Journal Title
  
  Curr Opin Nephrol Hypertens
  
  Volume: 23 Issue: 2 Pages: 161-8
- DOI
  10.1097/01.mnh.0000441049.98664.6c
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-25893045
[Journal Article] The potential for renoprotection with incretin-based drugs2014
- Author(s)
  Tanaka T, Higashijima Y, Wada T, Nangaku M
- Journal Title
  
  Kidney Int
  
  Volume: 86 Issue: 4 Pages: 701-711
- DOI
  10.1038/ki.2014.236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J03553, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-26461215
[Journal Article] Hypoxia and fibrosis in chronic kidney disease: crossing at pericytes2014
- Author(s)
  Kawakami T, Mimura I, Shoji K, Tanaka T, Nangaku M
- Journal Title
  
  Kidney Int Suppl
  
  Volume: 1 Pages: 107-112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461215
[Journal Article] Hypoxia as a key player in the AKI-to-CKD transition.2014
- Author(s)
  Tanaka S, Tanaka T, Nangaku M.
- Journal Title
  
  Am J Phyisol Renal Physiol
  
  Volume: 307 Issue: 11 Pages: F1187-F1195
- DOI
  10.1152/ajprenal.00425.2014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24591189, KAKENHI-ORGANIZER-26111001, KAKENHI-PROJECT-26461215
[Journal Article] Cross-enhancement of ANGPTL4 transcription by HIF1 alpha and PPAR beta/delta is the result of the conformational proximity of two response elements.2014
- Author(s)
  Inoue T, Kohro T, Tanaka T, Kanki Y, Li G, Poh HM, Mimura I, Kobayashi M, Taguchi A, Maejima T, Suehiro JI, Sugiyama A, Kaneki K, Aruga H, Dong S, Stevens JF, Yamamoto S, Tsutsumi S, Fujita T, Ruan X, Aburatani H, Nangaku M, Ruan Y, Kodama T, Wada Y.
- Journal Title
  
  Genome Biology
  
  Volume: 15 Issue: 4
- DOI
  10.1186/gb-2014-15-4-r63
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-24390213, KAKENHI-PUBLICLY-25118505, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25125707, KAKENHI-PROJECT-25670035, KAKENHI-PROJECT-25670619, KAKENHI-PROJECT-26250041, KAKENHI-PROJECT-26430121, KAKENHI-PROJECT-26670397, KAKENHI-PROJECT-26710013, KAKENHI-PROJECT-26860627
[Journal Article] Angiogenesis and hypoxia.2013
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Nature Rev Nephrol
  
  Volume: 9 Issue: 4 Pages: 211-22
- DOI
  10.1038/nrneph.2013.35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390213
[Journal Article] Angiogenesis and hypoxia in the kidney2013
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Nat Rev Nephrol
  
  Volume: 9(4) Pages: 211-22
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Structure-based drug design for hypoxia-inducible factor prolyl-hydroxylase inhibitors and its therapeutic potential for the treatment of erythropoiesis-stimulating agent-resistant anemia: raising expectations for exploratory clinical trials2013
- Author(s)
  Higashijima Y, Tanaka T, Nangaku M
- Journal Title
  
  Expert Opin Drug Discov
  
  Volume: 8 Issue: 8 Pages: 965-976
- DOI
  10.1517/17460441.2013.796358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Novel therapeutic strategy with hypoxia-inducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis2013
- Author(s)
  Mimura I, Tanaka T, Nangaku M
- Journal Title
  
  Semin Nephrol
  
  Volume: 33(4) Pages: 375-82
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Endoplasmic reticulum stress signal impairs erythropoietin production : a role for ATF42013
- Author(s)
  Chiang CK, Nangaku M, Tanaka T, Iwawaki T, Inagi R
- Journal Title
  
  Am J Physiol Cell Physiol.
  
  Volume: 304(4)
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Endoplasmic reticulum stress signal impairs erythropoietin production:a role for ATF4.2013
- Author(s)
  Chiang CK, Nangaku M, Tanaka T, IwawakiT, Inagi R.
- Journal Title
  
  Am J Physiol Cell Physiol.
  
  Volume: 304(4) Issue: 4 Pages: C342-C353
- DOI
  10.1152/ajpcell.00153.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590880, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-25461207, KAKENHI-PUBLICLY-24113702
[Journal Article] Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia2013
- Author(s)
  Tanaka T, Yamaguchi J, Higashijima Y, Nangaku M
- Journal Title
  
  FASEB J
  
  Volume: 27 Issue: 10 Pages: 4059-4075
- DOI
  10.1096/fj.13-231837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24390213
[Journal Article] Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates cytokinesis, and its expression correlates with the prognosis of renal cell carcinoma2013
- Author(s)
  Shoji K, Murayama T, Mimura I, Wada T, Kume H, Goto A, Ohse T, Tanaka T, Inagi R, van der Hoorn FA, Manabe I, Homma Y, Fukayama M, Sakurai T, Hasegawa T, Aburatani H, Kodama T, Nangaku M
- Journal Title
  
  Am J Pathol.
  
  Volume: 182(6) Pages: 2191-203
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Sperm-associated antigen 4, a novel hypoxia-inducible factor 1 target, regulates eytokinesis, and its expression correlates with the prognosis of renal cell earcinoma.2013
- Author(s)
  Shoji K, Mimura I, Murayama T, Wada T, Kume H, Goto A, Ohse T, Tanaka T, Inagi R, van der Hoorn FA, Manabe I, Homma Y, Fukayama M, Sakurai T, Hasegawa T, Aburatani H, Kodama T, Nangaku M.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 182 Issue: 6 Pages: 2191-2203
- DOI
  10.1016/j.ajpath.2013.02.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-22590307, KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24390213, KAKENHI-PROJECT-24590330, KAKENHI-PROJECT-24591189, KAKENHI-PROJECT-25290051, KAKENHI-PROJECT-25460431, KAKENHI-PROJECT-25461207
[Journal Article] Structure-based drug design for hypoxia-inducible factor prolyl-hydroxylase inhibitors and its therapeutic potential for the treatment of erythropoiesis-stimulating agent-resistant anemia : raising expectations for exploratory clinical trials2013
- Author(s)
  Higashijima Y, Tanaka T, Nangaku M
- Journal Title
  
  Expert Opin Drug Discov
  
  Volume: 8(8) Pages: 965-76
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia2013
- Author(s)
  Tanaka T, Yamaguchi J, Higashijima Y, Nangaku M
- Journal Title
  
  FASEB J.
  
  Volume: 27(10) Pages: 4059-75
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Novel therapeutic strategy with hypoxia-inducible factors via reversible epigenetic regulation mechanisms in progressive tubulointerstitial fibrosis.2013
- Author(s)
  Mimura I, Tanaka T, Nangaku M.
- Journal Title
  
  Seminars in Nephrology
  
  Volume: 33 Issue: 4 Pages: 375-382
- DOI
  10.1016/j.semnephrol.2013.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J08634, KAKENHI-PROJECT-24390213
[Journal Article] Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents2012
- Author(s)
  Tanaka T
- Journal Title
  
  Exp Cell Res
  
  Volume: 318 Issue: 9 Pages: 1068-1073
- DOI
  10.1016/j.yexcr.2012.02.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Dysregulated oxygen metabolism of the kidney by uremic toxins2012
- Author(s)
  Chiang CK, Tanaka T, Nangaku M
- Journal Title
  
  J Ren Nutr
  
  Volume: 22 Pages: 77-80
- URL
  http://www.sciencedirect.com/science/article/pii/S1051227611002184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents2012
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Exp Cell Res
  
  Volume: 318 Pages: 1068-73
- URL
  http://dx.doi.org/10.1016/j.yexcr.2012.02.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591020
[Journal Article] Dysregulated oxygen metabolism of the kidney by uremic toxins : review2012
- Author(s)
  Chiang CK, Tanaka T
- Journal Title
  
  J Ren Nutr
  
  Volume: 22 Pages: 77-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells.2012
- Author(s)
  Muratsu-Ikeda S, Nangaku M, Ikeda Y,Tanaka T, Wada T, Inagi R.
- Journal Title
  
  PLoS One.
  
  Volume: 7(7) Issue: 7 Pages: e41462-e41462
- DOI
  10.1371/journal.pone.0041462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590880, KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24591189
[Journal Article] Dysregulated oxygen metabolism of the kidney by uremic toxins : review2012
- Author(s)
  Chiang CK, Tanaka T, Nangaku M
- Journal Title
  
  J Ren Nutr
  
  Volume: 22(1) Pages: 77-80
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Downregulation of miR-205 modulates cell susceptibility to oxidative and endoplasmic reticulum stresses in renal tubular cells2012
- Author(s)
  Muratsu-Ikeda S, Nangaku M, Ikeda Y, Tanaka T, Wada T, Inagi R
- Journal Title
  
  PLoS One
  
  Volume: 7(7)
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host2012
- Author(s)
  Tanaka T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 42 Pages: 34866-34882
- DOI
  10.1074/jbc.m112.374587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781, KAKENHI-PROJECT-24390213
[Journal Article] Anthracycline inhibits recruitment of hypoxia-inducible transcription factors and suppresses tumor cell migration and cardiac angiogenic response in the host2012
- Author(s)
  Tanaka T, Yamaguchi J, Shoji K, Nangaku M
- Journal Title
  
  J Biol Chem.
  
  Volume: 287(42) Pages: 34866-82
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents2012
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Exp Cell Res
  
  Volume: 318(9) Pages: 1068-73
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner2011
- Author(s)
  Chiang CK, Tanaka T
- Journal Title
  
  Lab Invest
  
  Volume: 91 Pages: 1564-1571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Pathogenesis of tubular interstitial nephritis2011
- Author(s)
  Tanaka T
- Journal Title
  
  Contrib.Nephrol
  
  Volume: 169 Pages: 297-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Epigenetic regulation for hypoxic response via HIF and histone demethylase2011
- Author(s)
  Mimura I, Tanaka T, Wada Y, Kodama T, Nangaku M.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115 Pages: 453-8
- URL
  http://dx.doi.org/10.1254/jphs.10R19FM
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591020
[Journal Article] Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner2011
- Author(s)
  Chiang CK, Tanaka T, Inagi R, Fujita T, Nangaku M
- Journal Title
  
  Lab Invest
  
  Volume: 91(11) Pages: 1564-71
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] The role of incretins in salt-sensitive hypertension : the potential use of dipeptidyl peptidase-IV inhibitors2011
- Author(s)
  Tanaka T
- Journal Title
  
  Curr Opin Nephrol Hypertens
  
  Volume: 20 Pages: 476-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] The role of incretins in salt-sensitive hypertension : the potential use of dipeptidyl peptidase-IV inhibitors2011
- Author(s)
  Tanaka T, Nangaku M, Nishiyama A
- Journal Title
  
  Curr Opin Nephrol Hypertens
  
  Volume: 20(5) Pages: 476-81
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery : epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes2011
- Author(s)
  Mimura I, Tanaka T, Wada Y, Kodama T, Nangaku M
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 115(4) Pages: 453-8
- NAID
  10029893172
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Pathogenesis of tubular interstitial nephritis2011
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Contrib Nephrol.
  
  Volume: 169 Pages: 297-310
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Epigenetic regulation for hypoxic response via HIF and histone demethylase2011
- Author(s)
  Mimura I, Tanaka T, Wada Y, Kodama T, Nangaku M.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115 Pages: 453-8
- URL
  https://www.jstage.jst.go.jp/article/jphs/advpub/0/advpub_10R19FM/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in a HIF-dependent manner2011
- Author(s)
  Chiang CK, Tanaka T, Inagi R, Fujita T, Nangaku M
- Journal Title
  
  Lab Invest
  
  Volume: 91 Issue: 11 Pages: 1564-71
- DOI
  10.1038/labinvest.2011.114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260, KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
[Journal Article] Forewarned is forearmed : arm with HIF activation2010
- Author(s)
  Nangaku M, Tanaka T
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 25(5) Pages: 1385-7
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] Cytoglobin, a novelglobin, plays an anti-fibrotic role in the kidney2010
- Author(s)
  Mimura I, Nangaku M, Nishi H, Inagi R, Tanaka T, Fujita T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299 Issue: 5 Pages: F1120-F1133
- DOI
  10.1152/ajprenal.00145.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
[Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2010
- Author(s)
  Kawakami T, Inagi R, Wada T, Tanaka T, Fujita T, Nangaku M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299 Issue: 3 Pages: F568-F576
- DOI
  10.1152/ajprenal.00659.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591020, KAKENHI-PROJECT-22590880
[Journal Article] Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress2010
- Author(s)
  Palm F, Nangaku M, Fasching A, Tanaka T, Nordquist L, Hansell P, Kawakami T, Nishijima F, Fujita T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease2010
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Curr Opin Nephrol Hypretens
  
  Volume: 19 Issue: 1 Pages: 43-50
- DOI
  10.1097/mnh.0b013e3283328eed
- Data Source
  KAKENHI-PROJECT-21591020
[Journal Article] Uremia induces abnormal oxygen consumption in tubules and aggravates chronic hypoxia of the kidney via oxidative stress2010
- Author(s)
  Palm F, Nangaku M, Fasching A, Tanaka T, Nordquist L, Hansell P, Kawakami T, Nishijima F, Fujita T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(2)
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] The role of hypoxia, increased oxygen consumption and HIF-1alpha in progression of chronic kidney disease2010
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Current Opinion in Nephrology and Hypertension 19(1)
  
  Pages: 43-50
- Data Source
  KAKENHI-PROJECT-20890053
[Journal Article] Cytoglobin, a novel globin, plays an antifibrotic role in the kidney2010
- Author(s)
  Mimura I, Nangaku M, Nishi H, Inagi R, Tanaka T, Fujita T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(5)
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] The role of hypoxia, increased oxygen consumption and HIF-lalpha in progression of chronic kidney disease2010
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Current Opinion in Nephrology and Hypertension 19
  
  Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890053
[Journal Article] Cytoglobin, a novel globin, plays an anti-fibrotic role in the kidney2010
- Author(s)
  Mimura I, Nangaku M, Nishi H, Inagi R, Tanaka T, Fujita T
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease2010
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  Curr Opin Nephrol Hypretens
  
  Volume: 19 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2010
- Author(s)
  Kawakami T, Inagi R, Wada T, Tanaka T, Fujita T, Nangaku M
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299(3)
- Data Source
  KAKENHI-PROJECT-22790781
[Journal Article] The role of hypoxia, increased oxygen consumption, and hypoxia-inducible factor-1 alpha in progression of chronic kidney disease.2010
- Author(s)
  Tanaka, Nangaku
- Journal Title
  
  Curr Op Nephrol Hypertens
  
  Volume: 19 Pages: 43-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Indoxyl sulfate inhibits proliferation of human proximal tubular cells via endoplasmic reticulum stress2010
- Author(s)
  Kawakami T, Inagi R, Wada T, Tanaka T, Fujita T, Nangaku M.
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Metallothionein is upregulated by hypoxia and stabilizes hypoxia-inducible factor in the kidney2009
- Author(s)
  Kojima I, Tanaka T, Inagi R, Nishi H, Aburatani H, Kato H, Miyata T, Fujita T, Nangaku M
- Journal Title
  
  Kidney Int
  
  Volume: 75 Issue: 3 Pages: 268-77
- DOI
  10.1038/ki.2008.488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591020
[Journal Article] Metallothionein is up-regulated by hypoxia and stabilizes HIF in the kidney2009
- Author(s)
  Kojima I, Tanaka T, Inagi R, Nishi H, Aburatani H, Kato H, Miyata T, Fujita T, Nangaku M
- Journal Title
  
  Kidney Int
  
  Volume: 75 Pages: 268-277
- URL
  http://dx.doi.org/10.1038/ki.2008.488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Prolyl hydroxylase inhibitors to active HIF as a novel therapeutic approach against CKD2009
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 109 Pages: 24-31
- URL
  http://joi.jlc.jst.go.jp/JST.JSTAGE/jphs/08R09FM?from=PubMed
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Journal Article] Prolyl hydroxylase inhibitors to active HIF as a novel therapeutic approachagainst CKD.2009
- Author(s)
  Tanaka T, Nangaku M
- Journal Title
  
  J Pharmacol Sci 109
  
  Pages: 24-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] 腎性貧血2023
- Author(s)
  田中哲洋
- Organizer
  第66回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] 本邦実臨床におけるKDIGO分類毎の臨床転帰に関する後ろ向きコホート研究REAL CKD研究2023
- Author(s)
  田中哲洋
- Organizer
  糖尿病性腎症研究会2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] 集学的なCKD診療のプラクティスポイント2023
- Author(s)
  田中哲洋
- Organizer
  第231回日本内科学会東北地方会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] CKDにおける治療薬最新知見：バルドキソロンメチル・セロンセルチブによる腎症進展抑制も含めて2023
- Author(s)
  田中哲洋
- Organizer
  日本動脈硬化学会・学術集会2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] HIF-PH阻害薬2023
- Author(s)
  田中哲洋
- Organizer
  日本抗加齢医学会2023
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] 低酸素からみる慢性腎臓病の病態と治療2023
- Author(s)
  田中哲洋
- Organizer
  日本内分泌学会第41回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] DKD治療としてのバルドキソロンメチルへの期待2023
- Author(s)
  田中哲洋
- Organizer
  第66回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] Oxygen metabolism in diabetic kidney disease.2023
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  60 th ERA congress.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07713
[Presentation] 低酸素障害としてのCKDの病態2022
- Author(s)
  田中哲洋
- Organizer
  第175回日本循環器学会東北地方会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] Hypoxia ＋ HIF-1α2022
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  Australian and New Zealand Society of Nephrology Annual Scientific Meeting 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] Clinical indication of HIF-PHD inhibitors - who and when?2022
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  Nephrology & Transplantation Update Course, Australian and New Zealand Society of Nephrology Annual Scientific Meeting 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 保存期CKDにおけるESA, HIF-PH阻害薬の選択2022
- Author(s)
  田中哲洋
- Organizer
  第52回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF signaling in CKD2022
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  第86回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PHI使用に関するエビデンスと適正な使用2022
- Author(s)
  田中哲洋
- Organizer
  第67回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PH阻害薬が腎疾患関連にもたらす影響の基礎的検討2022
- Author(s)
  田中哲洋
- Organizer
  第46回日本鉄バイオサイエンス学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] CKD診療における最近の話題2022
- Author(s)
  田中哲洋
- Organizer
  日本内科学会東北支部主催　第226回東北地方会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 血流調節からみる慢性腎臓病の病態2022
- Author(s)
  田中哲洋
- Organizer
  CVMW2022　心血管代謝週間
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PH阻害薬をどう使うか2022
- Author(s)
  田中哲洋
- Organizer
  第67回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] ESA/HIF-PH阻害薬の切替、ナイーブ患者では2021
- Author(s)
  田中哲洋
- Organizer
  第66回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 近位尿細管におけるHIF-PH 阻害は虚血再灌流障害後の腎障害を軽減する2021
- Author(s)
  坂下碧、菅原真衣、田中哲洋、南学正臣
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 腎性貧血治療薬エナロデュスタットの作用機序および有効性の検討2021
- Author(s)
  田中哲洋, 福井健人，照屋慶太，藤岡正樹，南学正臣
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] ヒストン修飾阻害薬Dznepは、TIMP2遺伝子領域のH3K4me3を減らすことで発現を減少させ、腎線維化を抑制する2021
- Author(s)
  山崎智貴、三村維真理、田中哲洋、南学正臣
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] H3K27脱メチル化酵素阻害薬GSKJ4の腎繊維化に与える影響2021
- Author(s)
  佐藤大、三村維真理、田中哲洋、南学正臣
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K08604
[Presentation] 腎硬化症における腎虚血の重要性：基礎の面から2021
- Author(s)
  田中哲洋
- Organizer
  第64回日本腎臓学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] p300/CBP関連因子（PCAF）はHIF-1活性を多段階的に制御する2021
- Author(s)
  倉田遊、田中哲洋、南学正臣
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PH阻害薬2021
- Author(s)
  田中哲洋
- Organizer
  第51回日本腎臓学会西部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] Overview of Anemia of CKD2021
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  ASN Kidney Week 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 腎性貧血に対するHIF-PH阻害薬 vs ESA2021
- Author(s)
  田中哲洋
- Organizer
  第51回日本腎臓学会東部学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 代謝を標的とした腎疾患の治療戦略2021
- Author(s)
  田中哲洋
- Organizer
  第118回日本内科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PH阻害薬エナロデュスタットの肝臓からのエリスロポエチン（EPO）産生への影響の検討2021
- Author(s)
  田中哲洋，福井健人，藤岡正樹，水戸部祐子，南学正臣
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 身近になった腎性貧血治療2021
- Author(s)
  田中哲洋
- Organizer
  日本内科学会関東支部主催第65回生涯教育講演会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PH阻害薬エナロデュスタットのがん原性及び腫瘍体積への影響の検討2021
- Author(s)
  田中哲洋，剣持佑介，福井健人，井上崚，藤岡正樹，南学正臣
- Organizer
  第64回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF-PHD阻害薬の腎臓への影響について2020
- Author(s)
  田中哲洋
- Organizer
  第63回日本腎臓学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF治療の現況と課題2020
- Author(s)
  田中哲洋
- Organizer
  第65回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 低酸素障害としての糖尿病性腎臓病2020
- Author(s)
  田中哲洋
- Organizer
  第35回日本糖尿病合併症学会・第26回日本糖尿病眼学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] 低酸素生物学とHIF2020
- Author(s)
  田中哲洋
- Organizer
  第65回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF活性化薬を用いた慢性腎臓病治療2020
- Author(s)
  田中哲洋
- Organizer
  第20回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08626
[Presentation] HIF STABILIZERS FOR THE TREATMENT OF RENAL ANEMIA2019
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  World Congress of Nephrology 2019
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] エリスロポエチン産生誘導と腎性貧血治療の新展開2019
- Author(s)
  田中哲洋
- Organizer
  脳心血管抗加齢研究会2019
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Treating Dyslipidemias & Hyperuricemia in kidney disease2019
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  PAKISTAN SOCIETY OF NEPHROLOGY CONFERENCE 2019
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] CKDと酸素代謝異常2019
- Author(s)
  田中哲洋、南学正臣
- Organizer
  第92回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Multiple consequences of HIF activation in CKD2019
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  第92回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] HIF-PHD阻害薬2019
- Author(s)
  田中哲洋
- Organizer
  第64回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] PHD阻害薬の臨床試験2019
- Author(s)
  田中哲洋
- Organizer
  第62回日本腎臓学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] 臓器透明化と酸素モニタリングを糸口とする虚血性腎障害の病態解明2019
- Author(s)
  田中哲洋
- Organizer
  第62回日本腎臓学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Determination of oxygen tension in normal and fibrotic kidney using phosphorescence lifetime imaging microscope.2018
- Author(s)
  Yosuke Hirakawa, Kiichi Mizukami, Tomoko Honda, Toshitada Yoshihara, Imari Mimura, Tetsuhiro Tanaka, Seiji Tobita, Masaomi Nangaku
- Organizer
  2018年度日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Hes1, a Newly Identified Downstream Mediator of α7nAChR on Macrophages in the Cholinergic Anti-Inflammatory Pathway, Plays a Protective Role in AKI2018
- Author(s)
  Inoue T, Abe C, Tanaka S, Rosin DL, Nangaku M, Wada Y, Okusa MD.
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02824
[Presentation] Inhibition of prolyl hydroxylase domain might suppress macrophage infiltration and cardiac fibrosis in the chronic kidney disease rat model with cardiomyopathy2018
- Author(s)
  Lisa Uchida, Tetsuhiro Tanaka, Hisako Saito, Kenji Fukui, Takeshi Wakashima, Masaomi Nanagaku
- Organizer
  ERA-EDTA meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] ATF6α and PPARα Cross-Talk Provides New Insights into Lipotoxicity-Induced Tubulointerstitial Fibrosis2018
- Author(s)
  Jao T-M, Inoue T, Sugahara M, Maekawa H, Ishimoto Y, Tanaka T, Nangaku M, Inagi R.
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02824
[Presentation] PHD inhibition reduces reactive oxidative stress in in vitro ischemia model2018
- Author(s)
  Marie Ito, Tetsuhiro Tanaka, Masaomi Nangaku
- Organizer
  ASN Kidney Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Pathophysiological impact of elasticity, estimated by atomic force microscopy, on podocyte function.2018
- Author(s)
  Ishimoto Y, Nangaku M, Tanaka S, Okabe S, Inagi R.
- Organizer
  ISN-Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] PHD Inhibition Reduces Reactive Oxidative Stress in In Vitro Ischemia Model2018
- Author(s)
  Ito M, Tanaka T, Wakashima T, Nangaku M, Fukui K.
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02824
[Presentation] Clinical Trials of PHD inhibitors2018
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  第63回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Epigenetic changes induced by HIF- hypoxic memory -2018
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  NephrologyMeet2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Multiple, Systemic Effects of PHD Inhibitors Signify an Anti-Fibrotic and Anti-Inflammatory Impact on Cardiovascular Complications in the Remnant Kidney2018
- Author(s)
  Lisa Uchida, Tetsuhiro Tanaka, Hisako Saito, Mai Sugahara, Kenji Fukui, Takeshi Wakashima, Masaomi Nangaku
- Organizer
  ASN Kidney Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Pathophysiological impact of elasticity, estimated by atomic force microscopy, on podocyte function.2018
- Author(s)
  Ishimoto Y, Nangaku M, Tanaka S, Okabe S, Inagi R.
- Organizer
  ISN-Frontiers Meetings 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Multiple, Systemic Effects of PHD Inhibitors Signify an Anti-Fibrotic and Anti-Inflammatory Impact on Cardiovascular Complications in the Remnant Kidney2018
- Author(s)
  Uchida L, Tanaka T, Saito H, Sugahara M, Fukui K, Wakashima T, Nangaku M.
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02824
[Presentation] Whole-Kidney Three-Dimensional Imaging Reveals the Progression of Renal Sympathetic Denervation after Ischemia-Reperfusion Injury2018
- Author(s)
  Hasegawa S, Fukagawa M, Ueda HR, Nangaku M, Tanaka T, Susaki EA, Komaba H, Wada T, Saito H, Sugahara M, Uchida L, Ito M.
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02824
[Presentation] A role of hypoxia-signaling in diabetic kidney disease2018
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  NephrologyMeet2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] DETERMINATION OF OXYGEN TENSION IN TUBULAR EPITHELIAL CELLS USING PHOSPHORESCENCE LIFETIME IMAGING MICROSCOPY.2018
- Author(s)
  Yosuke Hirakawa, Kiichi Mizukami, Toshitada Yoshihara, Tomoko Honda, Imari Mimura, Tetsuhiro Tanaka, Seiji Tobita, Masaomi Nangaku.
- Organizer
  ERA-EDTA meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] The effect of HIF stabilizers on anemia, CKD and metabolic disorders2018
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  2018年度日本腎臓学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] Gene expression profiles of glomeruli from BTBR ob/ob mice treated with propel hydroxyls inhibitor suggest involvement of extracellular matrix modulators in pathogenesis of diabetic kidney disease2017
- Author(s)
  Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease.2017
- Author(s)
  Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M.
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Inhibition of Prolyl Hydroxylase Domain (PHD) Reduces Glomerular Macrophage Infiltration and Improves Albuminuria in Mice with a High Fat Diet2017
- Author(s)
  Saito H, Tanaka T, Sugahara M, Fukui K, Wakashima T, Nangaku M.
- Organizer
  The 51st Annual Meeting of the American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] Inhibition of propel hydroxyls domain (PHD) reduces glomerular macrophage infiltration and improves albuminuria in mice with a high fat diet.2017
- Author(s)
  Saito H, Tanaka T, Sugahara M, Fukui K, Wakashima T, Nangaku M
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease.2017
- Author(s)
  Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M.
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] Epigenetic change induced by HIF: hypoxic memory.2017
- Author(s)
  Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
- Organizer
  Uppsala Kidney Oxygen Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] ATF6 Knockout Mice Revealed That ER Stress Links Lipotoxicity and Kidney Fibrosis.2017
- Author(s)
  Jao TM, Nangaku M, Wu CH, Sugahara M, Saito S, Ishimoto Y, Maekawa H, Aoe M, Tanaka T, Inagi R.
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Inhibition of prolyl hydroxylase domain (PHD) reduces glomerular macrophage infiltration and improves albuminuria in mice with high fat diet2017
- Author(s)
  Hisako Saito, Tetsuhiro Tanaka, Mai Sugahara, Kenji Fukui, Takeshi Wakashima, Masaomi Nangaku
- Organizer
  ASN Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] ATF6 Knockout Mice Revealed That ER Stress Links Lipotoxicity and Kidney Fibrosis.2017
- Author(s)
  Jao TM, Nangaku M, Wu CH, Sugahara M, Saito S, Ishimoto Y, Maekawa H, Aoe M, Tanaka T, Inagi R.
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] 低酸素のイメージング2017
- Author(s)
  田中哲洋
- Organizer
  2017年度日本腎臓学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] PHD阻害薬は2型糖尿病マウスのアルブミン尿を減少させ、糖と脂質代謝を改善する.2017
- Author(s)
  菅原真衣、田中真司、齊藤久さこ、福井健人、石本　遊、稲城玲子、南学正臣、田中哲洋.
- Organizer
  第６０回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/ob Mice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease2017
- Author(s)
  Sugahara M, Tanaka T, Tanaka S, Fukui K, Shimizu A, Ishimoto Y, Inagi R, Nangaku M.
- Organizer
  The 51st Annual Meeting of the American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] ATF6 knockout mice revealed that ER stress links lipotoxicity and kidney fibrosis.2017
- Author(s)
  Jao TM, Wu CH, Sugahara M, Saito H, Ishimoto Y, Okada A, Maekawa H, Aoe M, Tanaka T, Nangaku M, Inagi R
- Organizer
  Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] Epigenetic change induced by HIF: hypoxic memory.2017
- Author(s)
  Nangaku M, Hirakawa Y, Mimura I, Inagi R, Tanaka T.
- Organizer
  Uppsala Kidney Oxygen Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] Gene Expression Profiles of Glomeruli from BTBR ob/obMice Treated with Prolyl Hydroxylase Inhibitor Suggest Involvement of Extracellular Matrix Modulators in Pathogenesis of Diabetic Kidney Disease2017
- Author(s)
  Mai Sugahara, Shinji Tanaka, Tetsuhiro Tanaka, Kenji Fukui, Akira Shimizu, Yu Ishimoto, Reiko Inagi, Masaomi Nangaku
- Organizer
  ASN Kidney Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] 酸素代謝異常からみた糖尿病性腎臓病2017
- Author(s)
  田中哲洋
- Organizer
  第54回日本臨床分子医学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09688
[Presentation] PHD阻害薬は2型糖尿病マウスのアルブミン尿を減少させ、糖と脂質代謝を改善する.2017
- Author(s)
  菅原真衣、田中真司、齊藤久さこ、福井健人、石本　遊、稲城玲子、南学正臣、田中哲洋.
- Organizer
  第６０回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Novel Therapeutic Modality of Kidney Diseases and Its Complication by PHD Inhibition2016
- Author(s)
  Tanaka Tetsuhiro
- Organizer
  ASN Kidney Week 2016
- Place of Presentation
  Chicago, IL, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] Prolyl hydroxylase inhibitor decreases albuminuria and improves glucose and lipid metabolism in a mouse model of type 2 diabetes2016
- Author(s)
  Tanaka S, Tanaka T, Sugahara M, Saito H, Inagi R, Nangaku M.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] Sodium-Glucose Cotransporter 2 Inhibition Partly Phenocopies Calorie Restriction in Kidneys of a Type 2 Diabetes Mouse Model2016
- Author(s)
  Shinji Tanaka, Tetsuhiro Tanaka, Mai Sugahara, Hisako Saito, Masaomi Nangaku
- Organizer
  Kidney Week 2016
- Place of Presentation
  McCormick Place（米国・シカゴ）
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] VAP-1酵素活性の阻害は、好中球浸潤の抑制を介して腎虚血再灌流障害を軽減する2016
- Author(s)
  田中真司、田中哲洋、稲城玲子、南学正臣
- Organizer
  第59回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K15465
[Presentation] Vascular Adhesion Protein-1 Promotes Neutrophil Infiltration via Hydrogen Peroxide Generation in Renal Ischemia-Reperfusion Injury2016
- Author(s)
  Shinji Tanaka, Tetsuhiro Tanaka, Mai Sugahara, Hisako Saito, Reiko Inagi, Masaomi Nangaku
- Organizer
  Kidney Week 2016
- Place of Presentation
  McCormick Place（米国・シカゴ）
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] VAP-1酵素活性の阻害は、好中球浸潤の抑制を介して腎虚血再灌流障害を軽減する2016
- Author(s)
  田中真司、田中哲洋、稲城玲子、南学正臣
- Organizer
  第59回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Prolyl hydroxylase inhibitor decreases albuminuria and improves glucose and lipid metabolism in a mouse model of type 2 diabetes2016
- Author(s)
  Tanaka S, Tanaka T, Sugahara M, Saito H, Inagi R, Nangaku M.
- Organizer
  Kidney Week 2016
- Place of Presentation
  Chicago
- Year and Date
  2016-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Prolyl Hydroxylase Inhibitor Decreases Albuminuria and Improves Glucose and Lipid Metabolism in a Mouse Model of Type 2 Diabetes2016
- Author(s)
  Shinji Tanaka, Tetsuhiro Tanaka, Mai Sugahara, Hisako Saito, Kenji Fukui, Yu Ishimoto, MD, Reiko Inagi, Masaomi Nangaku
- Organizer
  Kidney Week 2016
- Place of Presentation
  McCormick Place（米国・シカゴ）
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] りん光寿命測定を用いた腎臓尿細管細胞内分圧の測定2015
- Author(s)
  平川陽亮、吉原利忠、神谷真子、三村維真理、田中真司、田中哲洋、浦野泰照、飛田成史、南学正臣
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-04
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] HIFと貧血と鉄代謝(hepcidin)2015
- Author(s)
  田中哲洋
- Organizer
  第60回日本透析医学会学術集会・総会．
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] GLP-1 Receptor Agonists and DPP-4 Inhibitors and Amelioration of Kidney Injury2015
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  ASN Kidney Week 2015
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-05
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] Inhibition of Vascular Adhesion Protein-1 Suppresses Neutrophil Infiltration and Preserves Renal Function in the Rat Model of Renal Ischemia–Reperfusion Injury.2015
- Author(s)
  Shinji Tanaka, Tetsuhiro Tanaka, Reiko Inagi, Masaomi Nangaku.
- Organizer
  The 49th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] Inhibition of collagen cross-linking by lysyl oxidase prevents hypertrophy and protects from diabetic nephropathy.2015
- Author(s)
  Tetsuhiro Tanaka, Shinji Tanaka, Hisako Saito, Junna Yamaguchi, Yoshiki Higashijima, Masaomi Nangaku.
- Organizer
  ERA-EDTA 52nd meeting
- Place of Presentation
  London, UK
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] Sodium-glucose cotransporter 2 inhibition ameliorates glomerular hyperfiltration without affecting renal/glomerular hypertrophy in a mouse model of type 2 diabetes.2015
- Author(s)
  Tanaka S, Tanaka T, Inagi R, Nangaku M.
- Organizer
  Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
- Place of Presentation
  ウエスティン都ホテル京都（京都府京都市）
- Year and Date
  2015-10-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] Palmitate suppresses EPO production via ER stress in renal EPO producing cells.2015
- Author(s)
  Anusomvongchai T, Tanaka S, Hirakawa Y, Suzuki n, Yamamoto M, Nangaku M, Inagi R.
- Organizer
  Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
- Place of Presentation
  ウエスティン都ホテル京都（京都府京都市）
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] Inhibition of Vascular Adhesion Protein-1 Suppresses Neutrophil Infiltration and Preserves Renal Function in the Rat Model of Renal Ischemia–Reperfusion Injury2015
- Author(s)
  Shinji Tanaka, Tetsuhiro Tanaka, Reiko Inagi, Masaomi Nangaku,
- Organizer
  Kidney Week 2015
- Place of Presentation
  San Diego Convention Center, San Diego, CA, USA
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09247
[Presentation] Inhibition of Vascular Adhesion Protein-1 Suppresses Neutrophil Infiltration and Preserves Renal Function in the Rat Model of Renal Ischemia–Reperfusion Injury2015
- Author(s)
  Tanaka S et al,
- Organizer
  Kidney Week 2015
- Place of Presentation
  San Diego, USA
- Year and Date
  2015-11-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0088
[Presentation] Emerging, potential therapeutic strategies in diabetic kidney disease2015
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  The 11th Annual convention and scientific seminar of Kidney Foundation
- Place of Presentation
  Dhaka, Bangladesh
- Year and Date
  2015-12-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] Expanding roles of tubulointerstitial hypoxia and its regulation in kidney2015
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  the 1 st international seminar on the construction and management of renal diseases
- Place of Presentation
  Hangzhou, China
- Year and Date
  2015-09-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] A search for circulating permeability factors in focal segmental glomerulosclerosis2015
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  The 11th Annual convention and scientific seminar of Kidney Foundation
- Place of Presentation
  Dhaka, Bangladesh
- Year and Date
  2015-12-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] Estimation of intracellular oxygen concentration in diabetic kidney by phosphorescence lifetime measurement.2015
- Author(s)
  Hirakawa Y, Mimura I, Yoshihara T, Kamiya M, Tanaka S, Tanaka T, Inagi R, Urano Y, Tobita S, Nangaku M.
- Organizer
  Keystone Symposia: Diabetes: New insights into molecular mechanisms and therapeutic strategies.
- Place of Presentation
  ウエスティン都ホテル京都（京都府京都市）
- Year and Date
  2015-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04835
[Presentation] A NON-TRANSCRIPTIONAL ROLE OF HYPOXIA-INDUCIBLE FACTOR (HIF)-1 IN DEFENSE AGAINST DNA DOUBLE STRAND INJURY.2014
- Author(s)
  Tetsuhiro Tanaka, Yoshiki Higashijima, Shinji Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  The 51st European Renal Association/European Dialysis and Transplantation Association
- Place of Presentation
  Amsterdam, the Netherlands
- Year and Date
  2014-06-02
- Data Source
  KAKENHI-PROJECT-24390213
[Presentation] INDOXYL SULFATE SUPPRESSES TRANSACTIVATION OF HYPOXIA-INDUCIBLE FACTOR 1 AND DYSREGULATES HYPOXIA RESPONSE IN RATS WITH CHRONIC KIDNEY DISEASE AND EXPERIMENTAL HEART FAILURE2013
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  ERA-EDTA 50th meeting 2013
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] HYPOXIA-INDUCIBLE FACTOR (HIF) 3 IS UPREGULATED BY HYPOXIA AND COUNTERACTS THE EPITHELIAL-MESENCHYMAL TRANSDIFFERENTIATION PROGRAM2013
- Author(s)
  Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  2013 World Congress of Nephrology
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] HYPOXIA-INDUCIBLE FACTOR (HIF) 3 IS UPREGULATED BY HYPOXIA AND COUNTERACTS THE EPITHELIAL-MESENCHYMAL TRANSDIFFERENTIATION PROGRAM2013
- Author(s)
  Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  ISN World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] An antifibrotic role of hypoxia-inducible factor 3 in renal tubular cells2013
- Author(s)
  Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] 低酸素転写因子による腎線維化抑制機構の解析2013
- Author(s)
  田中哲洋, 正路久美, 山口純奈, 南学正臣
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia.2013
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Yoshiki Higashijima, Masaomi Nangaku
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Indoxyl sulfate signals for rapid mRNA stabilization of Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2 (CITED2) and suppresses the expression of hypoxia-inducible genes in experimental CKD and uremia2013
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Yoshiki Higashijima, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] INDOXYL SULFATE UPREGULATES CBP/p300-INTERACTING TRANSACTIVATOR 2 (CITED2) AND IMPAIRS THE INDUCTION OF HYPOXIA-INDUCIBLE GENES IN EXPERIMENTAL CKD AND HEART FAILURE MODELS2013
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  ISN World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] インドキシル硫酸はCITED2の発現誘導を介してCKDおよび心不全の低酸素遺伝子転写を減弱させる2013
- Author(s)
  田中哲洋, 山口純奈, 南学正臣
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] INDOXYL SULFATE UPREGULATES CBP/p300-INTERACTING TRANSACTIVATOR 2 (CITED2) AND IMPAIRS THE INDUCTION OF HYPOXIA-INDUCIBLE GENES IN EXPERIMENTAL CKD AND HEART FAILURE MODELS2013
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  2013 World Congress of Nephrology
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] 新規HIF-1ターゲット分子SPAG4は細胞質分裂を調節し、腎細胞癌の進行に重要な役割を果たす2013
- Author(s)
  正路久美, 村山尚, 三村維真理, 和田健彦, 久米春喜, 後藤明輝, 大瀬貴元, 田中哲洋, 稲城玲子, 油谷浩幸, 児玉龍彦, 南学正臣
- Organizer
  日本臨床分子医学会学術総会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] INDOXYL SULFATE SUPPRESSES TRANSACTIVATION OF HYPOXIA-INDUCIBLE FACTOR 1 AND DYSREGULATES HYPOXIA RESPONSE IN RATS WITH CHRONIC KIDNEY DISEASE AND EXPERIMENTAL HEART FAILURE2013
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  the 50th ERA-EDTA Congress
- Place of Presentation
  Istanbul, Turkey
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] An antifibrotic role of hypoxia-inducible factor 3 in renal tubular cells2013
- Author(s)
  Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  ASN Kidney Week 2013
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] 尿細管におけるHypoxia-inducible factor(HIF)-3αの低酸素発現調節機構の解析2012
- Author(s)
  田中哲洋, 正路久美, 山口純奈, 南学正臣
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Identification and Characterization of a Novel HIF-1 Target that Regulates Cytokinesis as a Defensive Mechanism against Polyploidy2012
- Author(s)
  Kumi Shoji, Imari Mimura, Takashi Murayama, Takehiko Wada, Tetsuhiro Tanaka, Takamoto Ohse, Reiko Inagi, Hiroyuki Aburatani, Tatsuhiko Kodama, Masaomi Nangaku
- Organizer
  American Society of Nephrology Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] インドキシル硫酸はMAPキナーゼ活性を介してCited2発現を亢進させ, 尿細管の低酸素応答を減弱させる2012
- Author(s)
  田中哲洋, 山口純奈, 南学正臣
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Hypoxia-inducible factor (HIF)-3α is a HIF-1 target gene and counteracts migration of proximal tubular cells in hypoxia2012
- Author(s)
  Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] 尿細管におけるHypoxia-inducible factor(HIF)-3αの低酸素発現調節機構の解析2012
- Author(s)
  田中哲洋
- Organizer
  第55回日本腎臓学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] 新規HIF-1ターゲット分子SPAG4は尿細管の細胞質分裂を調節する2012
- Author(s)
  正路久美, 村山尚, 三村維真理, 和田健彦, 久米春喜, 後藤明輝, 大瀬貴元, 田中哲洋, 稲城玲子, 油谷浩幸, 児玉龍彦, 南学正臣, 藤田敏郎
- Organizer
  第５５回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] 小胞体ストレスシグナル(unfolded protein response)による低酸素応答性エリスロポエチン産生機構の破綻2012
- Author(s)
  Chiang Chih-Kang, 南学正臣, 田中哲洋, 和田健彦, 大瀬貴元, 藤田敏郎, 稲城玲子
- Organizer
  第５５回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] Anthracycline inhibits recruitment of hypoxia-inducible transcription factors, blunts the induction of lysyl oxidase and suppresses migration of renal cell carcinoma2012
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Kumi Shoji, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Downregulation of miR-205 Modulates Cell Susceptibility to Oxidative and Endoplasmic Reticulum Stresses in Renal Tubular Cells2012
- Author(s)
  Shiyo Muratsu, Masaomi Nangaku, Yoichiro Ikeda, Tetsuhiro Tanaka, Takehiko Wada, Reiko Inagi
- Organizer
  American Society of Nephrology Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] Anthracycline Inhibits Recruitment of Hypoxia-Inducible Transcription Factors, Blunts the Induction of Lysyl Oxidase and Suppresses Migration of Renal Cell Carcinoma.2012
- Author(s)
  Tanaka T, et al.
- Organizer
  The 45^<th> Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  California, USA
- Data Source
  KAKENHI-PROJECT-24390213
[Presentation] microRNAによるprolyl hydroxylase domain 1(PHD1)の転写後制御を介した腎尿細管細胞のストレス応答調節機構2012
- Author(s)
  村津四葉, 南学正臣, 田中哲洋, 池田洋一郎, 和田健彦, 大瀬貴元, 藤田敏郎, 稲城玲子
- Organizer
  第５５回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] Indoxyl sulfate induces Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2), via the mitogen-activated protein kinase cascade and impairs hypoxia response of tubular epithelial cells2012
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Hypoxia-inducible factor (HIF)-3α is a HIF-1 target gene and counteracts migration of proximal tubular cells in hypoxia.2012
- Author(s)
  Tetsuhiro Tanaka
- Organizer
  ASN kidney week 2012
- Place of Presentation
  米国・サンディエゴ
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Identification of a Novel Hypoxia-Inducible Factor 1 (HIF-1) Regulator, CCAAT/Enhancer-Binding Protein Delta (CEBPD) in Kidney Disease2012
- Author(s)
  Junna Yamaguchi, Tetsuhiro Tanaka, Nobuaki Eto, Takamoto Ohse, Takehiko Wada, MD, Reiko Inagi, Masaomi Nangaku
- Organizer
  American Society of Nephrology Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] アントラサイクリン系抗癌剤は低酸素転写因子HIFの抑制を介して尿細管上皮由来細胞の浸潤能を低下させる2012
- Author(s)
  田中哲洋, 南学正臣
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Identification & Characterization of a Novel Oncogenic HIF-1 Target Involved in Renal Cell Carcinoma2011
- Author(s)
  Shoji K, Mimura I, Ohse T, Murayama T, Inagi R, Wada T, Tanaka T, Kume H, Goto A, Fujita T, Aburatani H, Kodama T, Nangaku M
- Organizer
  The 44^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Derangement of Oxygen Sensing for Erythropoietin(EPO) Production by Unfolded Protein Response2011
- Author(s)
  Inagi R, Chiang CK, Tanaka T, Fujita T, Nangaku M
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] Indoxyl sulfate, a representative uremic toxin, suppresses erythropoietin production in HIF-dependent manner2011
- Author(s)
  Chiang CK, Inagi R, Tanaka T, Fujita T, Nangaku M
- Organizer
  7^<th> International Congress on Uremia Research and Toxicity
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Indoxyl Sulfate Induces Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-Terminal Domain, 2, and Impairs Hypoxia Response in Proximal Tubular Cells2011
- Author(s)
  Tanaka T, Fujita T, Nangaku M
- Organizer
  The 44^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Indoxyl sulfate impairs hypoxia response in cultured proximal tubular cells2011
- Author(s)
  Tetsuhiro Tanaka, Toshiro Fujita, Masaomi Nangaku
- Organizer
  7th International Congress on Uremia Research and Toxicity 2011
- Place of Presentation
  Nagoya, Japan
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Indoxyl sulfate impairs hypoxia response in cultured proximal tubular cells2011
- Author(s)
  Tanaka T, Fujita T, Nangaku M
- Organizer
  7^<th> International Congress on Uremia Research and Toxicity
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Identification & Characterization of a Novel OncogenicHIF-1 Target Involved in Renal Cell Carcinoma2011
- Author(s)
  Shoji K, Mimura I, Ohse T, Murayama T, Inagi R, Wada T, Tanaka T, Kume H, GotoA, Fujita T, Aburatani H, Kodama T, Nangaku M
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] Indoxyl sulfate impairs hypoxia response in cultured proximal tubular cells2011
- Author(s)
  Tanaka, et al.
- Organizer
  7^<th> International Congress on Uremia Research and Toxicity
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Indoxyl Sulfate Induces Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-Terminal Domain, 2, and Impairs Hypoxia Response in Proximal Tubular Cells2011
- Author(s)
  Tanaka, et al.
- Organizer
  The 44^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, U.S.A.
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] 酸化ストレスおよび小胞体(ER)ストレス応答における腎尿細管細胞のmicroRNA発現変動2011
- Author(s)
  村津四葉、南学正臣、田中哲洋、Chih-KangChiang、和田健彦、藤田敏郎、稲城玲子
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] 尿毒素インドキシル硫酸が尿細管低酸素応答に及ぼす影響2011
- Author(s)
  田中哲洋, 南学正臣, 藤田敏郎
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Indoxyl sulfate induces Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, and impairs hypoxia response in proximal tubular cells2011
- Author(s)
  Tetsuhiro Tanaka, Toshiro Fujita, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2011
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Derangement of Oxygen Sensing for Erythropoietin(EPO) Production by Unfolded Protein Response(UPR)2011
- Author(s)
  Inagi R, Chiang CK, Tanaka T, Fujita T, Nangaku M
- Organizer
  The 44^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, U. S. A
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Elucidation of the Anti-Fibrotic Mechanism of a Novel HIF-Regulated Globin, Cytoglobin, with Molecular Genetics2010
- Author(s)
  Mimura I, Nishi H, Tanaka T, Inagi R, Fujita T, Nangaku M
- Organizer
  The 43^<rd> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U. S. A
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] アントラサイクリン系抗癌剤が尿細管低酸素応答に及ぼす影響2010
- Author(s)
  田中哲洋, 南学正臣, 藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] MicroRNA Profiles of Tubular Cells under Hypoxia-Reoxygenation and Endoplasmic Reticulum Stress2010
- Author(s)
  Muratsu S, Nangaku M, Tanaka T, Chiang CK, Wada T, Fujita T, Inagi R
- Organizer
  The 43^<rd> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U. S. A
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Endoplasmic Reticulum Stress Disturbs Erythropoietin Gene Expression in a HIF-Dependent Manner2010
- Author(s)
  Chiang CK, Nangaku M, Tanaka T, Fujita T, Inagi R
- Organizer
  The 43^<rd> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U. S. A
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Impact of Anthracyclines on Hypoxia Response in Tubular Epithelial Cells2010
- Author(s)
  Tanaka T, Fujita T, Nangaku M
- Organizer
  The 43^<rd> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U. S. A
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] MicroRNA Profiles of Tubular Cells under Hypoxia-Reoxygenation and Endoplasmic Reticulum Stress2010
- Author(s)
  Muratsu S, Nangaku M, Tanaka T, Chiang CK, Wada T, Fujita T, Inagi R
- Organizer
  The 43rd Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U. S. A.
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] Impact of anthracyclines on hypoxia response in tubular epithelial cells2010
- Author(s)
  Tetsuhiro Tanaka, Toshiro Fujita, Masaomi Nangaku
- Organizer
  American Society of Nephrology Renal Week 2010
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] 尿毒素インドキシル硫酸は近位尿細管の酸素消費を亢進させ,慢性低酸素をもたらす2010
- Author(s)
  田中哲洋, 南学正臣, 川上貴久, 西島冬彦, 坂内堅二, Fredrik Palm, 藤田敏郎
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790781
[Presentation] Endoplasmic Reticulum Stress Disturbs Erythropoietin Gene Expression ina HIF-Dependent Manner.2010
- Author(s)
  Chiang CK, Nangaku M, Tanaka T, Fujita T, Inagi R
- Organizer
  The 43rd Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U. S. A
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] Impact of Anthracyclines on Hypoxia Response in Tubular Epithelial Cells.2010
- Author(s)
  Tanaka, et al.
- Organizer
  The 43rd Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, U.S.A.
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats2009
- Author(s)
  Kumagai T, Nangaku M, Kojima I, Nishi H, Tanaka T, Miyata T, Fujita T, Inagi R
- Organizer
  World Congress of Nephrology
- Place of Presentation
  Milan, Italy
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Hypoxia-induced endoplasmic reticulum stress is ameliorated by glyoxalase I via reduction of intraWorld Congress of Nephrologycellular oxidative stress2009
- Author(s)
  Inagi R, Nishi H, Tanaka T, Miyata T, Fujita T, Nangaku M
- Organizer
  World Congress of Nephrology
- Place of Presentation
  Milan, Italy
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-21390260
[Presentation] Hypoxia-induced endoplasmic reticulum stress is amelioratedby glyoxalase I via reduction of intracellular oxidative stress2009
- Author(s)
  Inagi R, Nishi H, Tanaka T, Miyata T, Fujita T, Nangaku M
- Organizer
  World Congress of Nephrology
- Place of Presentation
  Italy
- Year and Date
  2009-05-25
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats2009
- Author(s)
  Kumagai T, Nangaku M, Kojima I, Nishi H, Tanaka T, Miyata T, Fujita T, Inagi R
- Organizer
  World Congress of Nephrology
- Place of Presentation
  Italy
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21591020
[Presentation] ラットThy-1腎炎モデルにおけるDPP-4阻害薬の腎保護効果に関する検討
- Author(s)
  東島佳毅、田中哲洋、山口純奈、田中真司、南学正臣
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-06-05 – 2015-06-07
- Data Source
  KAKENHI-PROJECT-24591189
[Presentation] 慢性腎臓病において低酸素が酸化ストレス障害に拮抗する新規分子機構
- Author(s)
  田中哲洋、田中真司、山口純奈、東島佳毅、南学正臣
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] Indoxyl Sulfate Signals for Rapid mRNA Stabilization of Cbp/p300-Interacting Transactivator with Glu/Asp-Rich Carboxy-Terminal Domain 2 (CITED2) and Suppresses the Expression of Hypoxia-Inducible Genes in Experimental CKD and Uremia.
- Author(s)
  Tetsuhiro Tanaka, Junna Yamaguchi, Yoshiki Higashijima, Masaomi Nangaku.
- Organizer
  The 46th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-24390213
[Presentation] An Antifibrotic Role of Hypoxia-Inducible Factor 3 in Renal Tubular Cells.
- Author(s)
  Tetsuhiro Tanaka, Kumi Shoji, Junna Yamaguchi, Masaomi Nangaku.
- Organizer
  The 46th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-24390213
[Presentation] A non-transcriptional role of hypoxia-inducible factor (hif)-1 in defense against dna double strand injury
- Author(s)
  Tetsuhiro Tanaka, Yoshiki Higashijima, Shinji Tanaka, Junna Yamaguchi, Masaomi Nangaku
- Organizer
  ERA-EDTA 51st meeting
- Place of Presentation
  Amsterdam
- Year and Date
  2014-05-31 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] 新規腎性貧血治療薬としてのPHD阻害薬
- Author(s)
  田中哲洋
- Organizer
  第57回日本腎臓学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Invited
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] 慢性腎臓病における低酸素応答ネットワークの解明
- Author(s)
  田中哲洋
- Organizer
  第57回日本腎臓学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-07-04 – 2014-07-06
- Invited
- Data Source
  KAKENHI-PROJECT-26461215
[Presentation] The Mechanism of ANGPTL4 Induction, a Mediator of Nephrotic Syndrome, through Its Chromatin Conformational Change.
- Author(s)
  Tsuyoshi Inoue, Imari Mimura, Takahide Kohro, Toshiya Tanaka, Hiroyuki Aburatani, Tatsuhiko Kodama, Youichiro Wada, Masaomi Nangaku
- Organizer
  The 46th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-24390213
[Presentation] Induction of CCAAT/Enhancer-Binding Protein Delta (CEBPD) Links Inflammation and Hypoxia to Injury by Regulating Hypoxia-Inducible Factor 1 (HIF-1).
- Author(s)
  Junna Yamaguchi, Tetsuhiro Tanaka, Nobuaki Eto, Masaomi Nangaku.
- Organizer
  The 46th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-24390213

1. NANGAKU Masaomi (90311620)

# of Collaborated Projects: 17 results

# of Collaborated Products: 147 results
2. INAGI Reiko (50232509)

# of Collaborated Projects: 16 results

# of Collaborated Products: 70 results
3. WADA Takehiko (90447409)

# of Collaborated Projects: 7 results

# of Collaborated Products: 22 results
4. Kawakami Takahisa (10722093)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
5. OHSE Takamoto (10568447)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. 加藤秀樹 (90625237)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
7. 三村維真理 (00727084)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
8. 西裕志 (90784174)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
9. KODAMA Tatsuhiko (90170266)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. ABURATANI Hiroyuki (10202657)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. 正路久美 (00439423)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 平川陽亮 (10780736)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 饒梓明 (30772446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 藤井輝夫 (30251474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 吉田瑶子 (90649443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 井上剛 (30821665)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 池田洋一郎 (10407398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 長谷川頌 (30892658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 木村啓志 (40533625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 平林祐介 (80447391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 佐藤恵美子 (20466543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 吉田舞 (20778469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 山越聖子 (50868099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 宮崎真理子 (60594695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 元池育子 (70347178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 三枝大輔 (90545237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 鈴木教郎 (20447254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 関根弘樹 (50506285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 佐藤浩司 (60888650)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 中井琢 (90971193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Shinohara Akinari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. Nasu Kahori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. DOI Kotaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. CHIKAMORI Masatomo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. ISHIMOTO Yu

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
36. OKADA Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. MATSUMOTO Yotaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. UEDA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. NOSO Shinsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 倉田遊

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
41. 菅原真衣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 洲崎悦生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 三島英換

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 池上博司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TANAKA TETSUHIRO 田中 哲洋

TANAKA Tetsuhiro 田中 哲洋

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of kidney protection by hypoxia-inducible factor 2Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Repair and regeneration of proximal tubular cells by inhibiting proxyl hydroxylasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic intervention of CKD targeting cellular oxygen sensorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

TANAKA TETSUHIRO 田中哲洋

TANAKA Tetsuhiro 田中哲洋