Yamawaki Yosuke 山脇洋輔

… Alternative Names

YAMAWAKI YOSUKE 山脇洋輔

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Researcher Number	90584061
Other IDs	https://orcid.org/0000-0002-7247-8295
Affiliation (Current)	2025: 第一薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 第一薬科大学, 薬学部, 准教授 2019 – 2023: 第一薬科大学, 薬学部, 講師 2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 助教 2017: 広島大学, 大学院医歯薬保健学研究科(歯), 助教 2014 – 2016: 広島大学, 医歯薬保健学研究院(歯), 助教 … More 2015: 広島大学, 医歯薬保健学研究院, 助教 2015: 広島大学, 大学院医歯薬保健学研究院, 助教 2013: 広島国際大学, 薬学部, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Psychiatric science / Pathobiological dentistry/Dental radiology Except Principal Investigator Basic Section 58050:Fundamental of nursing-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 59040:Nutrition science and health science-related / Psychiatric science / Pathobiological dentistry/Dental radiology / Functional basic dentistry
Keywords	Principal Investigator 炎症 / ミクログリア / ストレス脆弱性 / うつ病 / 炎症性サイトカイン / グリア / 精神疾患 / 肥満 / レプチン / 神経炎症 … More / 拘束ストレス / 肥満病態 / 免疫 / 歯性感染 / 中枢機能障害 / 神経細胞 / 歯周病 / 抗うつ薬 / NF-κB / PgLPS / 歯周病モデル / サイトカイン / 摂食行動 / グリア細胞 / 中枢炎症 / PRIP / うつ病様行動 / HDAC阻害薬 / エピジェネティクス … More Except Principal Investigator 機械学習 / 潰瘍性大腸炎 / 亜硫酸由来ラジカル / 共同創造 / 薬理学教育 / 精神看護 / コンコーダンス / 共同意思決定 / 困難 / ニード / 当事者 / 協働 / 看護師 / 薬剤師 / アクティブ・ラーニング / 症例シナリオ / 薬物療法 / 看護基礎教育 / 食行動 / 中脳腹側被蓋野 / レプチン / ドパミン / 脳内食報酬系 / 高脂肪食 / 肥満 / 脳神経疾患 / 前頭前野 / リアルタイムfMRI / うつ病 / Depression / 浸潤・転移 / シグナル伝達 / イノシトールリン脂質結合性タンパク質 / 細胞周期 / 癌転移 / 癌細胞浸潤 / 乳がん細胞株 / 肺がん細胞株 / イノシトールリン脂質結合性タンパク質 / がん細胞浸潤・転移 / 細胞運動 / AKT / PI(3,4,5)P3 / PI3K / PRIP / リン脂質代謝 / 細胞増殖 / 細胞浸潤 / 癌 / ベージュ細胞 / 寒冷刺激 / 脂肪分化 / 褐色脂肪細胞 / 白色脂肪細胞 / 脂肪代謝 / エネルギー代謝 / 脱分化 / 分化 / 脂肪細胞 Less

肥満病態下におけるミクログリア機能障害によるストレス脆弱性形成機構の解明Principal Investigator
- Principal Investigator
  
  山脇洋輔
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
亜硫酸由来ラジカル産生の制御に基づく潰瘍性大腸炎創薬基盤の創成
- Principal Investigator
  
  安川圭司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kurume University
看護基礎教育における薬物療法アクティブ・ラーニングプログラムの開発
- Principal Investigator
  
  吉武毅人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
精神看護における薬理学教育プログラムの開発～当事者と薬剤師・看護師の共同創造～
- Principal Investigator
  
  宮崎初
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58050:Fundamental of nursing-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Research for elucidating mechanism of stress vulnerability mediated by adipokine-evoked microglial activation in the obesityPrincipal Investigator
- Principal Investigator
  
  山脇洋輔
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
脳内報酬系レプチン－ドパミン連関を介した肥満における過食形成機序
- Principal Investigator
  
  小山進
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Research for elucidating mechanisms of stress vulnerability as basis of brain dysfunction caused by periodontal diseasePrincipal Investigator
- Principal Investigator
  
  Yamawaki Yosuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
  Hiroshima University
Study on PRIP roles in cancer cell proliferation and migration
- Principal Investigator
  
  Kanematsu Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Hiroshima University
Mechanisms of stress response relating to medication for depressive disorder focused on microgliaPrincipal Investigator
- Principal Investigator
  
  Yamawaki Yosuke
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hiroshima University
Basic research on elucidation of neurocircuit pathology of depression and its remodeling mechanism
- Principal Investigator
  
  Yamawaki Shigeto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Psychiatric science
- Research Institution
  Hiroshima University
Studies on molecular mechanisms in differentiation and dedifferentiation of adipocytes.
- Principal Investigator
  
  Kanematsu Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Research of microglial epigenetics as a mechanism of constructing stress vulnerabilityPrincipal Investigator
- Principal Investigator
  
  YAMAWAKI YOSUKE
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Hiroshima University
  Hiroshima International University

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain2024
- Author(s)
  Kana Oue, Yosuke Yamawaki, Kazuhisa Ouhara, Eiji Imado, Tetsuya Tamura, Mitsuru Doi, Yoshitaka Shimizu, Mitsuhiro Yoshida, Noriyoshi Mizuno, Norimitsu Morioka, Takashi Kanematsu, Masahiro Irifune, Yukio Ago
- Journal Title
  
  Journal of Oral Microbiology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K11588
[Journal Article] 薬剤師と精神科看護師との連携・協働の現状と課題～薬剤師の視点に焦点を当てて～2024
- Author(s)
  宮﨑初、栗原はるか、中本亮、山脇洋輔、安藤満代
- Journal Title
  
  第一薬科大学研究年報
  
  Volume: 40 Pages: 6177-6177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10775
[Journal Article] 医療領域における多職種連携－看護師と薬剤師に着目してー2024
- Author(s)
  安藤満代、宮﨑初、栗原はるか、山脇洋輔、中本亮
- Journal Title
  
  西九州大学こども学部紀要
  
  Volume: 15 Pages: 4852-4852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10775
[Journal Article] 高脂肪食負荷肥満誘発における脳内食報酬系ドパミン神経のレプチンとドパミンの相互作用2023
- Author(s)
  小山　進, 山脇　洋輔, 安川　圭司.
- Journal Title
  
  心身医学
  
  Volume: 64巻1号 Pages: 53-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11595
[Journal Article] Peripheral Immune Activation in Mice Elicits Unfolded Protein Responses Independent on MyD88 Pathway in the Liver but not the Hypothalamus and Hippocampus2022
- Author(s)
  Yosuke Yamawaki, Hitomi Kimura, Susumu Nagata, Koichiro Ozawa, Toru Hosoi
- Journal Title
  
  Frontier in Physiology
  
  Volume: 13 Pages: 854538-854538
- DOI
  10.3389/fphys.2022.854538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K11588
[Journal Article] Imipramine prevents Porphyromonas gingivalis lipopolysaccharide-induced microglial neurotoxicity2022
- Author(s)
  Yamawaki Yosuke、So Hiroki、Oue Kana、Asano Satoshi、Furusho Hisako、Miyauchi Mutsumi、Tanimoto Kotaro、Kanematsu Takashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 634 Pages: 92-99
- DOI
  10.1016/j.bbrc.2022.09.109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-21K11588, KAKENHI-PROJECT-20K09905
[Journal Article] Antidepressant effect of the translocator protein antagonist ONO-2952 on mouse behaviors under chronic social defeat stress2020
- Author(s)
  Nozaki Kanako、Ito Hikaru、Ohgidani Masahiro、Yamawaki Yosuke、Sahin Ezgi Hatice、Kitajima Takashi、Katsumata Seishi、Yamawaki Shigeto、Kato Takahiro A.、Aizawa Hidenori
- Journal Title
  
  Neuropharmacology
  
  Volume: 162 Pages: 107835-107835
- DOI
  10.1016/j.neuropharm.2019.107835
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-18H04042
[Journal Article] Anti-inflammatory Effects of miRNA-146a Induced in Adipose and Periodontal Tissues2020
- Author(s)
  Taiki Sanada, Tomomi Sano, Yusuke Sotomaru, Rehab Alshargabi, Yosuke Yamawaki, Akiko Yamashita, Hiroaki Matsunaga, Misaki Iwashita, Takanori Shinjo, Takashi Kanematsu, Tomoichiro Asano, Fusanori Nishimura
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: Jul Pages: 100757-100757
- DOI
  10.1016/j.bbrep.2020.100757
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19H01056
[Journal Article] Importance of the Habenula for Avoidance Learning Including Contextual Cues in the Human Brain: A Preliminary fMRI Study2020
- Author(s)
  Yoshino A, Okamoto Y, Sumiya Y, Okada G,Takamura M, Ichikawa N, Nakano T, Shibasaki C, Aizawa H, Yamawaki Y, Kawakami K, Yokoyama S, Yoshimoto J, Yamawaki S
- Journal Title
  
  Frontiers in Human Neuroscience
  
  Volume: 14 Pages: 165-165
- DOI
  10.3389/fnhum.2020.00165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K07561, KAKENHI-PROJECT-19K08021
[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019
- Author(s)
  Takashi Kanematsu, Kana Ouea, Toshiya Okumura, Kae Haradaa, Yosuke Yamawaki, Satoshi Asano, Akiko Mizokami, Masahiro Irifune, and Masato Hirata
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11503
[Journal Article] Phospholipase C-related catalytically inactive protein regulates lipopolysaccharide-induced hypothalamic inflammation-mediated anorexia in mice2019
- Author(s)
  Yamawaki Yosuke、Shirawachi Satomi、Mizokami Akiko、Nozaki Kanako、Ito Hikaru、Asano Satoshi、Oue Kana、Aizawa Hidenori、Yamawaki Shigeto、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Neurochemistry International
  
  Volume: 131 Pages: 104563-104563
- DOI
  10.1016/j.neuint.2019.104563
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06504, KAKENHI-PROJECT-18K09521, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-19K17112, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PROJECT-17K17254
[Journal Article] Immobilization stress induces XBP1 splicing in the mouse brain.2019
- Author(s)
  Hosoi T, Kimura H, Yamawaki Y, Mori K, Ozawa K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 508 Issue: 2 Pages: 516-520
- DOI
  10.1016/j.bbrc.2018.11.167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18KT0072, KAKENHI-PROJECT-16K08271, KAKENHI-PROJECT-18K06549
[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure2019
- Author(s)
  Kanematsu T, Oue K, Okumura T, Harada K, Yamawaki Y, Asano S, Mizokami A, Irifune M, Hirata M
- Journal Title
  
  J Oral Biosci
  
  Volume: 61(2) Issue: 2 Pages: 65-72
- DOI
  10.1016/j.job.2019.04.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K17254
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Phospholipase C-related catalytically inactive protein regulates cytokinesis by protecting phosphatidylinositol 4,5-bisphosphate from metabolism in the cleavage furrow2019
- Author(s)
  Asano, S., Ikura, Y., Nishimoto, M., Yamawaki, Y., Hamao, K., Kamijo, K., Hirata, M. and Kanematsu, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 12729-12729
- DOI
  10.1038/s41598-019-49156-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670
[Journal Article] Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice2018
- Author(s)
  Yamawaki Y, Yoshioka N, Nozaki K, Ito H, Oda K, Harada K, Shirawachi S, Asano S, Aizawa H, Yamawaki S, Kanematsu T, Akagi H
- Journal Title
  
  Brain research
  
  Volume: 1;1680 Pages: 13-38
- DOI
  10.1016/j.brainres.2017.12.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19459, KAKENHI-PLANNED-26112010, KAKENHI-PROJECT-16H07001, KAKENHI-PROJECT-17K11644
[Journal Article] Data on the effect of maternal separation coupled with social isolation in a forced swim test and gene expression of glial fibrillary acid protein in the prefrontal cortex of rats2018
- Author(s)
  Yamawaki Y, Nishida M, Harada K. Akagi H
- Journal Title
  
  Data in Brief
  
  Volume: 18 Pages: 496-500
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11670
[Journal Article] 総説うつ病における手綱核の役割-これまでのヒト脳に関する知見を中心に2018
- Author(s)
  Yoshino A, Aizawa H, Takamura M, Ichikawa N, Shibasaki C, Yamawaki Y, Sasaoka T, Okamoto Y, Yamawaki S.
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 70 Issue: 9 Pages: 1017-1023
- DOI
  10.11477/mf.1416201121
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2018-09-01
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11670
[Journal Article] Differential effects of chronic stress in young-adult and old female mice: cognitive-behavioral manifestations and neurobiological correlates.2017
- Author(s)
  Lotan A, Lifschytz T, Wolf G, Keller S, Ben-Ari H, Tatarsky P, Pillar N, Oved K, Sharabany J, Merzel TK, Matsumoto T, Yamawaki Y, Mernick B, Avidan E, Yamawaki S, Weller A, Shomron N, Lerer B.
- Journal Title
  
  Molecular Psychiatry
  
  Volume: - Issue: 2 Pages: 158-175
- DOI
  10.1007/s10905-018-9665-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11670
[Journal Article] Regional brain functions in the resting state indicative of potential differences between depression and chronic pain2017
- Author(s)
  Yoshino Atsuo、Okamoto Yasumasa、Doi Mitsuru、Otsuru Naofumi、Okada Go、Takamura Masahiro、Ichikawa Naho、Yokoyama Satoshi、Yamashita Hidehisa、Yamawaki Shigeto
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 3003-3003
- DOI
  10.1038/s41598-017-03522-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02552
[Journal Article] Effects of behavioral activation on the neural basis of other perspective self referential processing in subthreshold depression: An fMRI study.2017
- Author(s)
  Shiota, S., Okamoto, Y., Okada, G., Takagaki, K., Takamura, M., Mori, A., Yokoyama, S., Nishiyama, Y., Jinnin, R., Hashimoto, R., & Yamawaki, S.
- Journal Title
  
  Psychological Medicine
  
  Volume: 47 Issue: 5 Pages: 877-888
- DOI
  10.1017/s0033291716002956
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-16H06396, KAKENHI-PLANNED-16H06399, KAKENHI-PROJECT-15J04535, KAKENHI-PROJECT-15J04679, KAKENHI-PROJECT-26461748, KAKENHI-PROJECT-15H02552
[Journal Article] Cognitive behavioral therapy changes functional connectivity between medial prefrontal and anterior cingulate cortices.2017
- Author(s)
  Yoshimura S, Okamoto Y, Matsunaga M, Onoda K, Okada G, Kunisato Y, Yoshino A, Ueda K, Suzuki SI, Yamawaki S.
- Journal Title
  
  J Affect Disord
  
  Volume: 208 Pages: 610-614
- DOI
  10.1016/j.jad.2016.10.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461748, KAKENHI-PROJECT-25780413, KAKENHI-PROJECT-26870375, KAKENHI-PROJECT-15H02552
[Journal Article] Differential effects of chronic stress in young-adult and old female mice: cognitive-behavioral manifestations and neurobiological correlates2017
- Author(s)
  Lotan A、Lifschytz T、Wolf G、Keller S、Ben-Ari H、Tatarsky P、Pillar N、Oved K、Sharabany J、Merzel T K、Matsumoto T、Yamawaki Y、Mernick B、Avidan E、Yamawaki S、Weller A、Shomron N、Lerer B
- Journal Title
  
  Molecular Psychiatry
  
  Volume: - Issue: 6 Pages: 1432-1445
- DOI
  10.1038/mp.2017.237
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02552
[Journal Article] Increased amygdala reactivity following early life stress: a potential resilience enhancer role.2017
- Author(s)
  Yamamoto T, Toki S, Siegle GJ, Takamura M, Takaishi Y, Yoshimura S, Okada G, Matsumoto T, Nakao T, Muranaka H, Kaseda Y, Murakami T, Okamoto Y, Yamawaki S
- Journal Title
  
  BMC psychiatry
  
  Volume: 17 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12888-017-1201-x
- NAID
  120006814094
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H07011, KAKENHI-PROJECT-26460731, KAKENHI-PROJECT-25780413, KAKENHI-PROJECT-15H02552
[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice display increased induction of uncoupling protein 1 in adipose tissues following chronic cold exposure.2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 印刷中 Issue: 2 Pages: 108-112
- DOI
  10.1016/j.job.2017.04.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20421
[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice.2017
- Author(s)
  Hayashiuchi M, Kitayama T, Morita K, Yamawaki Y, Oue K, Yoshinaka T, Asano S, Harada K, Kang Y, Hirata M, Irifune M, Okada M, Kanematsu T.
- Journal Title
  
  Journal of Anesthesia
  
  Volume: in press Issue: 4 Pages: 531-538
- DOI
  10.1007/s00540-017-2350-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K11313
[Journal Article] Identifying melancholic depression biomarker using whole-brain functional connectivity2017
- Author(s)
  Ichikawa N, Lisi G, Yahata N, Okada G, Takamura M, Yamada M, Suhara T, Hashimoto R, Yamada T, Yoshihara Y, Takahashi H, Kasai K, Kato N, Yamawaki S, Kawato M, Morimoto J, Okamoto Y
- Journal Title
  
  ArXiv
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02552
[Journal Article] Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling2017
- Author(s)
  Asano Satoshi、Taniguchi Yuri、Yamawaki Yosuke、Gao Jing、Harada Kae、Takeuchi Hiroshi、Hirata Masato、Kanematsu Takashi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 5408-5408
- DOI
  10.1038/s41598-017-05908-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11479, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11649, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-15K11039
[Journal Article] Patients with major depressive disorder exhibit reduced reward size coding in the striatum2017
- Author(s)
  Takamura Masahiro、Okamoto Yasumasa、Okada Go、Toki Shigeru、Yamamoto Tetsuya、Ichikawa Naho、Mori Asako、Minagawa Hideaki、Takaishi Yoshiyuki、Fujii Yasutaka、Kaichi Yoko、Akiyama Yuji、Awai Kazuo、Yamawaki Shigeto
- Journal Title
  
  Progress in Neuro-Psychopharmacology and Biological Psychiatry
  
  Volume: 79 Pages: 317-323
- DOI
  10.1016/j.pnpbp.2017.07.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02552, KAKENHI-PROJECT-16H07011
[Journal Article] Disrupted Brain Activation and Deactivation Pattern during Semantic Verbal Fluency Task in Patients with Major Depression.2017
- Author(s)
  Takamura M, Okamoto Y, Okada G, Toki S, Yamamoto T, Yamamoto O, Jitsuiki H, Yokota N, Tamura T, Kurata A, Kaichi Y, Akiyama Y, Awai K, Yamawaki S
- Journal Title
  
  Neuropsychobiology
  
  Volume: 74 Issue: 2 Pages: 69-77
- DOI
  10.1159/000453399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07011, KAKENHI-PROJECT-15H02552
[Journal Article] Phospholipase C-related catalytically inactive protein can regulate obesity, a state of peripheral inflammation.2017
- Author(s)
  Yamawaki Y, Oue K, Shirawachi S, Asano S, Harada K, Kanematsu T.
- Journal Title
  
  Japanese Dental Science Review
  
  Volume: 53（1） Issue: 1 Pages: 18-24
- DOI
  10.1016/j.jdsr.2016.06.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254
[Journal Article] Immobilization stress-induced anorexia is mediated independent of MyD88.2016
- Author(s)
  Hosoi T, Yamawaki Y, Kimura H, Ozawa K
- Journal Title
  
  Neuroreport
  
  Volume: 27 Issue: 13 Pages: 947-7
- DOI
  10.1097/wnr.0000000000000641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19731
[Journal Article] The potential use of histone deacetylase inhibitors in the treatment of depression2015
- Author(s)
  Fuchikami M, Morinobu S, et al.
- Journal Title
  
  Progress in Neuro-Psychopharmacology & Biological Psychiatry
  
  Volume: 62 Pages: 00059-7
- DOI
  10.1016/j.pnpbp.2015.03.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25116518, KAKENHI-PROJECT-25861036, KAKENHI-PROJECT-15K09810, KAKENHI-PROJECT-15K19731
[Journal Article] Phospholipase C-related catalytically inactive protein is a new modulator of thermogenesis promoted by β-adrenergic receptors in brown adipocytes2015
- Author(s)
  Kana Oue, Jun Zhang, Kae Harada-Hada, Satoshi Asano, Yosuke Yamawaki, Masaki Hayashiuchi, Hisako Furusho, Takashi Takata, Masahiro Irifune, Masato Hirata, Takashi Kanematsu
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Issue: 8 Pages: 4185-96
- DOI
  10.1074/jbc.m115.705723
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20437
[Journal Article] Possible involvement of rumination in gray matter abnormalities in persistent symptoms of major depression: An exploratory magnetic resonance imaging voxel-based morphometry study.2014
- Author(s)
  Machino, A., Kunisato, Y., Matsumoto, T., Yoshimura, S., Ueda, K., Yamawaki, Y., ... & Yamawaki, S.
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 168 Pages: 229-235
- DOI
  10.1016/j.jad.2014.06.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25780413, KAKENHI-PROJECT-25780428, KAKENHI-PROJECT-25861036
[Presentation] イミプラミンは炎症状態下においてAKT-GSK3β経路を介した MEF2Dタンパク上昇によってインターロイキン-10の発現を増強させる2023
- Author(s)
  山脇　洋輔
- Organizer
  日本薬学会　第143年会
- Data Source
  KAKENHI-PROJECT-21K11588
[Presentation] Tricyclic antidepressant imipramine inhibits lipopolysaccaride derived Porphyromonas gingivaris activated microglia induced neural impairment2023
- Author(s)
  Yosuke Yamawaki, Takashi Kanematsu
- Organizer
  第53回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K11588
[Presentation] 高脂肪食投与による易肥満マウスにおいては、脳内食報酬系ドパミン神経の興奮が高まる.2022
- Author(s)
  小山　進, 山脇　洋輔, 安川　圭司.
- Organizer
  第63回日本心身医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K11595
[Presentation] Possible involvement of AKT-GSK3β signal-up-regulated MEF2D protein in imipramine-enhanced the expression of astrocytic interleukin-10 under inflammatory state2019
- Author(s)
  Yamawaki Y., Shirawachi S., Takaishi M., Yamawaki S., Kanematsu T.
- Organizer
  AsCNP2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] 医療ビックデータ時代における精神疾患の革新的診断・治療法の開発2018
- Author(s)
  山脇成人
- Organizer
  日本製薬工業協会　医療健康分野のビックデータ活用研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] 精神医療に求められるエビデンス：脳科学に基づく新たな診療・治療法の開発～うつ病を例として2018
- Author(s)
  山脇成人
- Organizer
  ヘルスデーターサイエンス研究所セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] Phospholipase C-related catalytically inactive protein regulates fat metabolism and energy expenditure2018
- Author(s)
  Takashi Kanematsu, Kana Oue, Yosuke Yamawaki, Satoshi Asano
- Organizer
  Obesity-2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Phospholipase C-related catalytically inactive protein regulates phosphatidylinositol metabolism and modulates cancer cell migration2018
- Author(s)
  Takashi Kanematsu, Satoshi Asano, Yosuke Yamawaki, Satoru Kusaka
- Organizer
  8th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] 炎症誘発性摂餌抑制行動における新規分子の解析2018
- Author(s)
  山脇　洋輔, 兼松　隆
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] A new molecular mechanism that regulates energy expenditure by regulating the function of white and brown adipocytes2018
- Author(s)
  Takashi Kanematsu, Kana Oue, Shuzo Sakata, Yosuke Yamawaki, Satoshi Asano
- Organizer
  The 60th Annual Meetings of Japanese Association for Oral Biology
- Invited
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] グリア細胞間相互作用におけるイミプラミンの抗炎症効果の検討2018
- Author(s)
  山脇洋輔、高石宗佳、山脇成人、兼松隆
- Organizer
  第28回日本臨床精神神経薬理学会・第48回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] Imipramine enhances the expression of astrocytic interleukin-10 under inflammatory state2018
- Author(s)
  Yosuke Yamawaki, Satomi Shirawachi, Munechika Takaishi, Shigeto Yamawaki, Takashi Kanematsu
- Organizer
  8th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] 歯周病原細菌由来リポ多糖（PgLPS）が惹起する脳内炎症の解析2018
- Author(s)
  曽浩紀，山脇洋輔，谷本幸太郎，兼松隆
- Organizer
  第102回広島大学歯学会例会
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] Depressive rumination reduced by realtime fMRI neurofeedback of the posterior cingulate cortex (PCC) activity2017
- Author(s)
  Ichikawa, N., Takamura, M., Okada, G., Yokoyama, S., Shibasaki, C., Yoshino, A., Matsumoto, Y., Araki, J., Koura, T., Sumiya, Y., Okamoto, Y. & Yamawaki, S
- Organizer
  Real-time Functional Imaging and Neurofeedback Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] こころの科学としての精神医学：その現状と展望2017
- Author(s)
  山脇成人
- Organizer
  第6回日本精神科医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] Lipopolysaccharideが誘発する摂食抑制行動におけるPLC-related catalytically inactive proteinの役割2017
- Author(s)
  白輪地　聡美, 山脇　洋輔, 兼松　隆
- Organizer
  第59回　歯科基礎医学会学術大会,
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] Deactivation of DMN nodes during DLPFC fMRI neurofeedback2017
- Author(s)
  Takamura, M, Okamoto, Y, Ichikawa, N, Okada, G, Yoshino, A, Shibasaki, C, Yamawaki, S.
- Organizer
  Real-time Functional Imaging and Neurofeedback Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] 精神・神経疾患の診断・治療法開発に向けた取り組みと現状の課題～うつ病を例として～2017
- Author(s)
  山脇成人
- Organizer
  文部科学省　科学技術・学術政策研究所講演会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] Anti-inflammatory effects of antidepressant in glial cells2017
- Author(s)
  山脇洋輔、白輪地聡美、高石宗佳、山脇成人、兼松　隆
- Organizer
  第50回　広島大学歯学会
- Data Source
  KAKENHI-PROJECT-17K11670
[Presentation] 5cmルールでのrTMSの施行は適切か?　Resting fMRIの知見から2017
- Author(s)
  横山仁史, 岡本泰昌, 岡田剛, 高村真広, 市川奈穂, 柴崎千代, 吉野敦雄, 山脇成人
- Organizer
  第14回日本うつ病学会総会・第17回日本認知療法・認知行動療法学会
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] A classifier of melancholic depression with whole-brain resting-state connectivity2017
- Author(s)
  Ichikawa, N., Lisi, G., Yahata, N., Okada, G., Takamura, M., Hashimoto, R., Yamada, T., Yamada, M., Suhara, T., Moriguchi, S., Mimura, M., Yoshihara, Y., Takahashi, H., Kasai, K., Kato, N., Yamawaki, S., Seymour, B., Kawato, M., Morimoto, J. & Okamoto, Y
- Organizer
  Real-time Functional Imaging and Neurofeedback Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] こころの脳科学イノベーション　うつ病医療からモノづくりまで2017
- Author(s)
  山脇成人, 岡本泰昌, 岡田剛, 吉野敦雄, 淵上学, 岡田怜, 山下英尚, 町野彰彦, 志々田一宏, 小早川誠, 神人蘭
- Organizer
  第113回日本精神神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] 脳とこころの科学から見た「うつ」と「希望」2017
- Author(s)
  山脇成人
- Organizer
  第28回日本緑内障学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] 脳科学を応用したネガティブ感性（うつ病）とポジティブ感性（ワクワク感）の可視化技術開発2017
- Author(s)
  山脇成人
- Organizer
  技術情報協会セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] 精神医学の新たな社会貢献～脳とこころの化学の産学官連携～2017
- Author(s)
  山脇成人
- Organizer
  第113回日本精神神経学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02552
[Presentation] PRIPによる脳内炎症が誘発する摂食抑制行動の調節2016
- Author(s)
  山脇洋輔, 白輪地聡美、兼松隆
- Organizer
  第58回歯科基礎医学会学術大会
- Place of Presentation
  北海道
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-15K19731
[Presentation] Phospholipase C-related catalytically inactive protein is involved in the neuroinflammation-induced anorexia2016
- Author(s)
  Yosuke Yamawaki, Satomi Shirawachi, Takashi Kanematsu
- Organizer
  30th International College of Neuropsychopharmacology (CINP) World Congress
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Phospholipase C-related catalytically inactive protein is involved in the neuroinflammation-induced anorexia2016
- Author(s)
  Yosuke Yamawaki, Satomi Shirawachi, Takashi Kanematsu
- Organizer
  CINP 2016
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19731
[Presentation] Phospholipase C-related catalytically inactive protein (Prip)欠損マウスにおけるLPS誘導性脳内炎症による摂食抑制行動の解析2016
- Author(s)
  山脇洋輔，白輪地聡美，兼松隆
- Organizer
  第４回口腔神経科学研究会
- Place of Presentation
  大阪市
- Data Source
  KAKENHI-PROJECT-16K11503
[Presentation] Sodium butyrate ameliorates inflammation-induced depression-like behavior via inhibition of microglial activation2015
- Author(s)
  Yosuke Yamawaki, Norika Yoshioka,　Misako Nishida, Ayaka Murai, Takashi Kanematsu, Hiroyuki Akagi
- Organizer
  CINP Dublin Thematic Meeting
- Place of Presentation
  Dublin / Ireland
- Year and Date
  2015-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19731
[Presentation] Gene expression analysis in microglia related in antidepressant-like effect of sodium butyrate2015
- Author(s)
  山脇洋輔, 兼松隆
- Organizer
  第57回　歯科基礎医学会
- Place of Presentation
  新潟
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K19731
[Presentation] ミクログリア抑制効果に基づくHDAC阻害薬の抗うつ効果の検討
- Author(s)
  山脇洋輔、吉岡伯華、西田美沙子、村井彩佳、吉野貴成、赤木宏行
- Organizer
  日本薬学会　第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25861036
[Presentation] 酪酸ナトリウムによる炎症誘発性うつ病様行動の改善効果
- Author(s)
  山脇洋輔, 吉岡伯華, 西田美沙子, 村井彩佳, 大植香菜, 林内優樹, 兼松隆, 赤木宏行
- Organizer
  第88回　日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25861036
[Presentation] Sodium butyrate ameliorates inflammation-induced depression-like behavior via inhibition of microglial activation
- Author(s)
  Yosuke Yamawaki, Norika Yoshioka, Misako Nishida, Ayaka Murai, Takashi Kanematsu, Hiroyuki Akagi
- Organizer
  CINP2015
- Place of Presentation
  ダブリン/英国
- Year and Date
  2015-06-03 – 2015-06-05
- Data Source
  KAKENHI-PROJECT-25861036

1. Kanematsu Takashi (10264053)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. ASANO SATOSHI (30570535)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 小山進 (60461505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
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# of Collaborated Projects: 2 results

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5. HARADA KAE (60432663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Yamawaki Shigeto (40230601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
7. Okamoto Yasumasa (70314763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. Okada Go (10457286)

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# of Collaborated Products: 8 results
9. Hashimoto Koichi (00303272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. Morioka Norimitsu (20346505)

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26. 宮崎初 (80612952)

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31. OUE KANA

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33. HASHIMOTO Ryuichiro

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34. Siegle Greg J.

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35. TAKAMURA Masahiro

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36. IRIFUNE Masahiro

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37. NAKATSU Yusuke

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38. 吉村晋平

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39. 伊藤日加瑠

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
40. 佐野朋美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
41. 山本哲也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
42. 森信繁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 高靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 平田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamawaki Yosuke 山脇 洋輔

YAMAWAKI YOSUKE 山脇 洋輔

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肥満病態下におけるミクログリア機能障害によるストレス脆弱性形成機構の解明Principal Investigator

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亜硫酸由来ラジカル産生の制御に基づく潰瘍性大腸炎創薬基盤の創成

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看護基礎教育における薬物療法アクティブ・ラーニングプログラムの開発

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精神看護における薬理学教育プログラムの開発～当事者と薬剤師・看護師の共同創造～

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Research for elucidating mechanism of stress vulnerability mediated by adipokine-evoked microglial activation in the obesityPrincipal Investigator

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脳内報酬系レプチン－ドパミン連関を介した肥満における過食形成機序

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Research for elucidating mechanisms of stress vulnerability as basis of brain dysfunction caused by periodontal diseasePrincipal Investigator

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Study on PRIP roles in cancer cell proliferation and migration

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Mechanisms of stress response relating to medication for depressive disorder focused on microgliaPrincipal Investigator

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Basic research on elucidation of neurocircuit pathology of depression and its remodeling mechanism

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Studies on molecular mechanisms in differentiation and dedifferentiation of adipocytes.

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Research of microglial epigenetics as a mechanism of constructing stress vulnerabilityPrincipal Investigator

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[Journal Article] Oral administration of Porphyromonas gingivalis to mice with diet-induced obesity impairs cognitive function associated with microglial activation in the brain2024

Author(s)

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Yamawaki Yosuke 山脇洋輔

YAMAWAKI YOSUKE 山脇洋輔