Kudo Yotaro 工藤洋太郎

… Alternative Names

KUDO Yotaro 工藤洋太郎

Less

Researcher Number	90608358
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 東京大学, 医学部附属病院, 助教 2014 – 2015: 東京大学, 医学部附属病院, 助教 2012 – 2013: 東京大学, 医学部附属病院, 特任臨床医
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator TET1 / 発がん促進性微小環境 / 膜タンパク質 / 慢性肝障害 / 肝細胞がん / 非典型PKC / 肝内胆管 / 非典型Protein Kinase C分子 / アラジール症候群 / 肝内胆管形成不全 … More / 非典型型Protein Kinase C / アラジール症候群（ALGS） / 消化器がん / 有糸分裂異常 / DNA脱メチル化 / がん / ヒドロキシメチル化シトシン / 肝臓学 … More Except Principal Investigator 肝細胞癌 / クロマチン / 薬物療法 / エピゲノム / 代謝 / 胆管癌 / うっ血肝 / FALD / Fontan / 膵癌 / バイオマーカー / 免疫チェックポイント阻害剤 / 分子標的薬 / 肝星細胞 / 肝脂肪化 / 肝線維化 / p62/Sequestosome1 / 代謝産物 / 肝星細胞活性化 / 肝内胆管癌 / HBV　Xタンパク / ユビキチンリガーゼ / ユビキチン化 / IGFBP1 / CHIP / CUL4-DDB1 / ユビキチン・プロテアソーム系 / HBx / HBV / リン脂質 / リン脂質代謝異常 / 非アルコール性脂肪肝炎 / 脂質生合成経路 / リン脂質代謝 / 非アルコール性脂肪性肝疾患 Less

膵癌の生物学的可塑性における三次元クロマチン構造の重要性と標的化
- Principal Investigator
  
  立石敬介
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  St. Marianna University School of Medicine
代謝とエピゲノムを基軸とした肝内胆管発癌機構の解明と新規治療標的の探索
- Principal Investigator
  
  藤原弘明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
レンバチニブによる肝細胞癌の細胞死はICIの相乗効果を引き起こすか
- Principal Investigator
  
  建石良介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
電解質輸送体による肝脂質代謝の制御Principal Investigator
- Principal Investigator
  
  工藤洋太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
肝癌薬物療法における奏功性に関わるケモカインの同定と治療標的としての可能性
- Principal Investigator
  
  山田友春
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Identification of pathogenesis and therapeutic targets in fontan-associated liver disease (FALD)
- Principal Investigator
  
  中塚拓馬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Analysis of chromatin structure for targeting pancreatic cancer
- Principal Investigator
  
  立石敬介
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  St. Marianna University School of Medicine
Unraveling the Pathophysiology of NASH through Changes in LipoQuality
- Principal Investigator
  
  Nakagawa Hayato
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Mie University
Development of novel therapies targeting host factors in Hepatitis B virus replication
- Principal Investigator
  
  Tanaka Yasuo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
肝内胆管癌におけるエピゲノムaddictionの包括的解明
- Principal Investigator
  
  木暮宏史
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Nihon University
  The University of Tokyo
Elucidation of the Molecular Mechanism of Hepatic Stellate Cell Activation Focusing on Cancer-Derived Metabolites
- Principal Investigator
  
  Minami Tatsuya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
非典型PKC分子による肝内胆管形成の分子学的制御機構Principal Investigator
- Principal Investigator
  
  工藤洋太郎
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Contribution of TET1 to a malignant phenotype in digestive cancer cells.Principal Investigator
- Principal Investigator
  
  Kudo Yotaro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Contribution of TET1 to malignant characteristics in digestive cancer cells.Principal Investigator
- Principal Investigator
  
  KUDO Yotaro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2024 2022 2021 2015 2013 2012 Other

All Journal Article Presentation

[Journal Article] Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis2022
- Author(s)
  Kawamura Satoshi、Matsushita Y、Kurosaki S、Tange M、Fujiwara N、Hayata Y、Hayakawa Y、Suzuki N、Hata M、Tsuboi M、Kishikawa T、Kinoshita H、Nakatsuka T、Sato M、Kudo Y、Hoshida Y、Umemura A、Eguchi A、Ikenoue T、Hirata Y、Uesugi M、Tateishi R、Tateishi Keisuke、Fujishiro Mitsuhiro、Koike K、Nakagawa H
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 132 Issue: 11
- DOI
  10.1172/jci151895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08028, KAKENHI-PROJECT-21H02892
[Journal Article] HNF1B‐driven three‐dimensional chromatin structure for molecular classification in pancreatic cancers2022
- Author(s)
  Kato Hiroyuki、Tateishi Keisuke、Iwadate Dosuke、Yamamoto Keisuke、Fujiwara Hiroaki、Nakatsuka Takuma、Kudo Yotaro、Hayakawa Yoku、Ijichi Hideaki、Otsuka Motoyuki、Kishikawa Takahiro、Takahashi Ryota、Miyabayashi Koji、Nakai Yousuke、Hirata Yoshihiro、Toyoda Atsushi、Morishita Shinichi、Fujishiro Mitsuhiro
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1672-1685
- DOI
  10.1111/cas.15690
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19517, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-21H02893, KAKENHI-PROJECT-21K15966, KAKENHI-PROJECT-23K07350, KAKENHI-PROJECT-21K07886, KAKENHI-PROJECT-21K07907, KAKENHI-PROJECT-23K24314
[Journal Article] MNX1-HNF1B Axis Is Indispensable for Intraductal Papillary Mucinous Neoplasm Lineages2022
- Author(s)
  Kato H, Tateishi K, Fujiwara H, Nakatsuka T, Yamamoto K, Kudo Y, Hayakawa Y, Nakagawa H, Tanaka Y, Ijichi H, Otsuka M, Iwadate D, Oyama H, Kanai S, Noguchi K, Suzuki T, Sato T, Hakuta R, Ishigaki K, Saito K, Saito T, Takahara N, Kishikawa T, Hamada T, Takahashi R, Miyabayashi K, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 162 Issue: 4 Pages: 1272-1287
- DOI
  10.1053/j.gastro.2021.12.254
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08362, KAKENHI-PROJECT-19K08435, KAKENHI-PROJECT-19K16533, KAKENHI-PROJECT-20K08353, KAKENHI-PROJECT-21K07886, KAKENHI-PROJECT-21K07935, KAKENHI-PROJECT-20K16154, KAKENHI-PROJECT-21K15368, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21K07906, KAKENHI-PROJECT-22K06976, KAKENHI-PROJECT-20K08324, KAKENHI-PROJECT-21K15966
[Journal Article] Post-treatment cell-free DNA as a predictive biomarker in molecular-targeted therapy of hepatocellular carcinoma2021
- Author(s)
  Nakatsuka T、Nakagawa H、Hayata Y、Wake T、Yamada T、Nishibatake Kinoshita M、Nakagmi R、Sato M、Minami T、Uchino K、Enooku K、Kudo Y、Tanaka Y、Kishikawa T、Otsuka M、Tateishi R、Koike K
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: - Issue: 5 Pages: 01773-4
- DOI
  10.1007/s00535-021-01773-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08352, KAKENHI-PROJECT-18H02789, KAKENHI-PROJECT-18K07900, KAKENHI-PROJECT-21K07906
[Journal Article] Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation2012
- Author(s)
  Kudo Y, Aburatani H, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 103 Issue: 4 Pages: 670
- DOI
  10.1111/j.1349-7006.2012.02213.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-22590717, KAKENHI-PROJECT-23790775, KAKENHI-PROJECT-24790682
[Presentation] Reconsidering Cholangiolocellular Carcinoma from 2 cases presenting with different characteristics.2024
- Author(s)
  Saito A, Gamo A, Tanaka Y, Kojima Y, Yanase M, Inagaki F, Kokudo N, Miyazaki H, Nakano M.
- Organizer
  The Asian Pacific Association for the Study of the Liver (APASL) Annual Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07906
[Presentation] 消化器癌におけるDNA脱メチル化酵素TET1の役割の検討2015
- Author(s)
  工藤洋太郎,立石敬介,永江玄太,山本恵介,中塚拓馬,浅岡良成,田中康雄,池上恒雄,白井聖一,関元昭,米沢理人,油谷浩幸,小池和彦
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26860494
[Presentation] Contribution of TET1 to malignant characteristics in digestive cancer cells2013
- Author(s)
  Yotaro Kudo, Keisuke Tateishi, Tsuneo Ikenoue, Keisuke Yamamoto, Shinzo Yamamoto, Yoshinari Asaoka, Hideaki Ijichi, Genta Nagae, Masato Yonezawa, Motoaki Seki, Kiyokazu Shirai, Haruhiko Yoshida, Hiroyuki Aburatani, Kazuhiko Koike
- Organizer
  Cell Symposia: Cancer Epigenomics
- Place of Presentation
  Sitges, Spain
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] 悪性形質転換におけるDNA脱メチル化反応中間体ヒドロキシメチル化シトシンの検討2013
- Author(s)
  工藤洋太郎、立石敬介、山本恵介、山本信三、浅岡良成、伊地知秀明、池上恒雄、白井聖一、永江玄太、吉田晴彦、油谷浩幸、小池和彦
- Organizer
  第50回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] Contribution of TET1 to malignant characteristics in digestive cancer cells2013
- Author(s)
  Yotaro Kudo, Keisuke Tateishi, Tsuneo Ikenoue, Keisuke Yamamoto, Shinzo Yamamoto, Yoshinari Asaoka, Hideaki Ijichi, Genta Nagae, Masato Yonezawa, Motoaki Seki, Kiyokazu Shirai, Haruhiko Yoshida, Hiroyuki Aburatani, Kazuhiko Koike
- Organizer
  Cell Symposia, Cancer Epigenomics
- Place of Presentation
  Sitges, Spain
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] 悪性形質転換における DNA脱メチル化反応中間体ヒドロキシメチル化シトシンの検討2013
- Author(s)
  工藤洋太郎、立石敬介、山本恵介、山本信三、浅岡良成、伊地知秀明、池上恒雄、白井聖一、永江玄太、吉田晴彦、油谷浩幸、小池和彦
- Organizer
  第50回日本臨床分子医学会学術総会
- Place of Presentation
  東京国際フォーラム, 東京
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] 悪性形質転換におけるヒドロキシメチル化シトシンの低下2012
- Author(s)
  工藤　洋太郎、立石　敬介、山本　恵介、山本　信三、浅岡　良成、伊地知　秀明、永江　玄太、油谷　浩幸、小池　和彦
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] 悪性形質転換におけるヒドロキシメチル化シトシンの低下2012
- Author(s)
  工藤洋太郎、立石敬介、山本恵介、山本信三、浅岡良成、伊地知秀明、永江玄太、油谷浩幸、小池和彦
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  学術総合センター, 東京
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] 消化器がんにおけるヒドロキシメチル化シトシンおよびDNA脱メチル化酵素TETの役割の検討2012
- Author(s)
  工藤　洋太郎、立石　敬介、山本　恵介、山本　信三、浅岡　良成*、伊地知　秀明*、池上　恒雄、永江　玄太、吉田　晴彦、油谷　浩幸、小池　和彦
- Organizer
  第20回浜名湖シンポジウム
- Place of Presentation
  アクトシティ浜松コングレスセンター
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation2012
- Author(s)
  Yotaro Kudo, Keisuke Tateishi, Yoshinari Asaoka, Hideaki Ijichi, Genta Nagae, Hiroyuki Aburatani, Kazuhiko Koike
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ニューオータニイン札幌, 札幌
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.2012
- Author(s)
  Yotaro Kudo, Keisuke Tateishi, Yoshinari Asaoka, Hideaki Ijichi, Genta Nagae, Hiroyuki Aburatani, Kazuhiko Koike
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、さっぽろ芸文館、札幌市教育文化会館
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] 消化器がんにおけるヒドロキシメチル化シトシンおよび DNA脱メチル化酵素 TET1の役割の検討2012
- Author(s)
  工藤洋太郎、立石敬介、山本恵介、山本信三、浅岡良成、伊地知秀明、池上恒雄、白井聖一、永江玄太、吉田晴彦、油谷浩幸、小池和彦
- Organizer
  第20回浜名湖シンポジウム
- Place of Presentation
  アクトシティ浜松コングレスセンター, 浜松
- Data Source
  KAKENHI-PROJECT-24790682
[Presentation] TET1 regulates proper mitotic process in cancer cell.
- Author(s)
  Yotaro Kudo, Keisuke Tateishi, Genta Nagae, Takuma Nakatsuka, Keisuke Yamamoto, Yoshinari Asaoka, Yasuo Tanaka, Tsuneo Ikenoue, Kiyokazu Shirai, Masato Yonezawa, Motoaki Seki, Hiroyuki Aburatani, Kazuhiko Koike
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-09-25 – 2015-09-27
- Data Source
  KAKENHI-PROJECT-26860494
[Presentation] 消化器癌におけるDNA脱メチル化酵素TET1の役割の検討
- Author(s)
  工藤洋太郎, 立石敬介, 永江玄太, 山本恵介, 中塚拓馬, 浅岡良成, 田中康雄, 池上恒雄, 白井聖一, 関元昭, 米沢理人, 油谷浩幸, 小池和彦
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2015-04-23 – 2015-04-25
- Data Source
  KAKENHI-PROJECT-26860494

1. 立石敬介 (20396948)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. Nakagawa Hayato (00555609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 建石良介 (50444089)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 山田友春 (60868024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 中塚拓馬 (50772042)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 山本恵介 (10608532)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 藤原弘明 (00814500)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Tanaka Yasuo (40422290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. Minami Tatsuya (60459401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 木暮宏史 (60568921)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 早河翼 (60777655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 畑昌宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 鈴木伸三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 岸川孝弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 濱田毅

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kudo Yotaro 工藤 洋太郎

KUDO Yotaro 工藤 洋太郎

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

電解質輸送体による肝脂質代謝の制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非典型PKC分子による肝内胆管形成の分子学的制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Contribution of TET1 to a malignant phenotype in digestive cancer cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Contribution of TET1 to malignant characteristics in digestive cancer cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis2022

Kudo Yotaro 工藤洋太郎

KUDO Yotaro 工藤洋太郎