Ura Hiroki 浦大樹

… Alternative Names

浦大樹ウラヒロキ

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Researcher Number	90624958
Other IDs	https://orcid.org/0000-0002-7600-3481
Affiliation (Current)	2024: 金沢医科大学, 総合医学研究所, 講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢医科大学, 総合医学研究所, 講師 2012: 独立行政法人理化学研究所, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Basic Section 42040:Laboratory animal science-related / Developmental biology Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords	Principal Investigator 発生 / エピジェネティックバリアー / DNAメチル化 / 幹細胞 / 細胞分化 / エピジェネティクス Except Principal Investigator 患者由来iPS細胞 / CoLAS / スプライシング / 遺伝子検査 … More / 生理活性物質 / 自発的運動 / 神経修復 / 脳損傷 / 老化 / 虐待 / 育児放棄 / 脳 / マウス / 小胞体ストレス / バイオマーカー / ハプロ不全 / ヒト末梢血由来iPS細胞 / モザイク変異 / 遺伝子型・表現型相関 / 結節性硬化症 Less

Functional analysis of endoplasmic reticulum stress disorders in the brain with a view to therapeutic interventions for inappropriate parenting
- Principal Investigator
  
  田中貴士
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kumamoto Health Science University
老化した脳で失われた神経修復能の回復を促す治療標的の探索
- Principal Investigator
  
  田中貴士
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Kumamoto Health Science University
The role of DNA methylation in epigenetic barrier between naive and primed statePrincipal Investigator
- Principal Investigator
  
  浦大樹
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kanazawa Medical University
患者血液由来全長cDNAを用いた新規オンデマンド遺伝子検査法の確立とその評価
- Principal Investigator
  
  研澄仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanazawa Medical University
結節性硬化症の超早期治療介入のための神経・精神症状重症度予測バイオマーカーの同定
- Principal Investigator
  
  新井田要
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kanazawa Medical University
細胞競合を介したマウス胚性幹細胞の細胞不均一性メカニズムの解明Principal Investigator
- Principal Investigator
  
  浦大樹
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  The Institute of Physical and Chemical Research

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Establishment of a human induced pluripotent stem cell line, KMUGMCi010-A, from a patient with X-linked Ohdo syndrome bearing missense mutation in the MED12 gene2024
- Author(s)
  Ura Hiroki、Togi Sumihito、Hatanaka Hisayo、Niida Yo
- Journal Title
  
  Stem Cell Research
  
  Volume: 77 Pages: 103388-103388
- DOI
  10.1016/j.scr.2024.103388
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07277
[Journal Article] Establishment of a human induced pluripotent stem cell line, KMUGMCi007-A, from a patient with prolidase deficiency (PD) bearing homozygous in-frame mutation in the PEPD gene2023
- Author(s)
  Ura Hiroki、Togi Sumihito、Ozaki Mamoru、Hatanaka Hisayo、Niida Yo
- Journal Title
  
  Stem Cell Research
  
  Volume: 69 Pages: 103075-103075
- DOI
  10.1016/j.scr.2023.103075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05607
[Journal Article] Recessive dystrophic epidermolysis bullosa caused by a novel COL7A1 variant with isodisomy2023
- Author(s)
  Niida Yo、Kobayashi Azusa、Togi Sumihito、Ura Hiroki
- Journal Title
  
  Human Genome Variation
  
  Volume: 10 Issue: 1
- DOI
  10.1038/s41439-023-00257-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05607
[Journal Article] Clinical Trial on the Safety and Tolerability of Personalized Cancer Vaccines Using Human Platelet Lysate-Induced Antigen-Presenting Cells2023
- Author(s)
  Koya Terutsugu、Yoshida Kenichi、Togi Misa、Niida Yo、Togi Sumihito、Ura Hiroki、Mizuta Shuichi、Kato Tomohisa、Yamada Sohsuke、Shibata Takeo、Liu Yi-Chang、Yuan Shyng-Shiou、Wu Deng-Chyang、Kobayashi Hirohito、Utsugisawa Taiju、Kanno Hitoshi、Shimodaira Shigetaka
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 14 Pages: 3627-3627
- DOI
  10.3390/cancers15143627
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05607, KAKENHI-PROJECT-23K06727
[Journal Article] SNP Array Screening and Long Range PCR-Based Targeted Next Generation Sequencing for Autosomal Recessive Disease with Consanguinity: Insight from a Case of Xeroderma Pigmentosum Group C2023
- Author(s)
  Nomura Fumie、Shimizu Akira、Togi Sumihito、Ura Hiroki、Niida Yo
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 11 Pages: 2079-2079
- DOI
  10.3390/genes14112079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05607, KAKENHI-PROJECT-23K07277
[Journal Article] An optimized cocktail of small molecule inhibitors promotes the maturation of dendritic cells in GM-CSF mouse bone marrow culture2023
- Author(s)
  Matsuba Shintaro、Ura Hiroki、Saito Fumiji、Ogasawara Chie、Shimodaira Shigetaka、Niida Yo、Onai Nobuyuki
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1264609-1264609
- DOI
  10.3389/fimmu.2023.1264609
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05607, KAKENHI-PROJECT-23K24117
[Journal Article] A Case of Von Hippel-Lindau Disease With Recurrence of Paraganglioma and No Other Associated Symptoms: The Importance of Genetic Testing and Establishing Follow-Up Policies2023
- Author(s)
  Okada Naoki、Shioya Akihiro、Togi Sumihito、Ura Hiroki、Niida Yo
- Journal Title
  
  Cureus
  
  Volume: － Pages: 50484-50484
- DOI
  10.7759/cureus.50484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05607, KAKENHI-PROJECT-23K07277
[Journal Article] Establishment of human induced pluripotent stem cell lines, KMUGMCi006, from a patient with Tuberous sclerosis complex (TSC) bearing mosaic nonsense mutations in the Tuberous sclerosis complex 2 (TSC2) gene2023
- Author(s)
  Ura Hiroki、Togi Sumihito、Ozaki Mamoru、Hatanaka Hisayo、Niida Yo
- Journal Title
  
  Stem Cell Research
  
  Volume: 70 Pages: 103129-103129
- DOI
  10.1016/j.scr.2023.103129
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07854, KAKENHI-PROJECT-23K05607, KAKENHI-PROJECT-23K07277
[Journal Article] Target-capture full-length double-stranded cDNA long-read sequencing through Nanopore revealed novel intron retention in patient with tuberous sclerosis complex2023
- Author(s)
  Ura Hiroki、Togi Sumihito、Niida Yo
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 14 Pages: 1256064-1256064
- DOI
  10.3389/fgene.2023.1256064
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07854, KAKENHI-PROJECT-23K05607, KAKENHI-PROJECT-23K07277
[Journal Article] Streamlining Genetic Diagnosis With Long-Range Polymerase Chain Reaction (PCR)-Based Next-Generation Sequencing for Type I and Type II Collagenopathies2023
- Author(s)
  Niida Yo、Togi Sumihito、Ura Hiroki
- Journal Title
  
  Cureus
  
  Volume: 15 Pages: 50482-50482
- DOI
  10.7759/cureus.50482
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07277
[Journal Article] <scp>Schimmelpenning‐Feuerstein‐Mims</scp> syndrome induced by <i>HRAS</i>?<scp>Gly12Ser</scp> somatic mosaic mutation: Case report and literature review2023
- Author(s)
  Ono Hiroto、Yamaguchi Reimon、Arai Minako、Togi Sumihito、Ura Hiroki、Niida Yo、Shimizu Akira
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 50 Issue: 9 Pages: 1213-1215
- DOI
  10.1111/1346-8138.16822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05607
[Journal Article] Genotype and Phenotype Landscape of 283 Japanese Patients with Tuberous Sclerosis Complex2022
- Author(s)
  Togi Sumihito、Ura Hiroki、Hatanaka Hisayo、Niida Yo
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 19 Pages: 11175-11175
- DOI
  10.3390/ijms231911175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07854
[Presentation] Genotype and phenotype landscape of 283 Japanese patients with tuberous sclerosis complex2023
- Author(s)
  Niida Y, Togi S, Ura H.
- Organizer
  Human Genetics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07854

1. 研澄仁 (40709391)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 田中貴士 (30734694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 新井田要 (40293344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 堀修 (60303947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 岩脇隆夫 (50342754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 竹屋元裕 (90155052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 古山貴文 (20802268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中聡 (10321944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 上野将紀 (40435631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ura Hiroki 浦 大樹

浦 大樹 ウラ ヒロキ

Research Projects

Research Products

Co-Researchers

Functional analysis of endoplasmic reticulum stress disorders in the brain with a view to therapeutic interventions for inappropriate parenting

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

老化した脳で失われた神経修復能の回復を促す治療標的の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of DNA methylation in epigenetic barrier between naive and primed statePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

患者血液由来全長cDNAを用いた新規オンデマンド遺伝子検査法の確立とその評価

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

結節性硬化症の超早期治療介入のための神経・精神症状重症度予測バイオマーカーの同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞競合を介したマウス胚性幹細胞の細胞不均一性メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of a human induced pluripotent stem cell line, KMUGMCi010-A, from a patient with X-linked Ohdo syndrome bearing missense mutation in the MED12 gene2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of a human induced pluripotent stem cell line, KMUGMCi007-A, from a patient with prolidase deficiency (PD) bearing homozygous in-frame mutation in the PEPD gene2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recessive dystrophic epidermolysis bullosa caused by a novel COL7A1 variant with isodisomy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical Trial on the Safety and Tolerability of Personalized Cancer Vaccines Using Human Platelet Lysate-Induced Antigen-Presenting Cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SNP Array Screening and Long Range PCR-Based Targeted Next Generation Sequencing for Autosomal Recessive Disease with Consanguinity: Insight from a Case of Xeroderma Pigmentosum Group C2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An optimized cocktail of small molecule inhibitors promotes the maturation of dendritic cells in GM-CSF mouse bone marrow culture2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Case of Von Hippel-Lindau Disease With Recurrence of Paraganglioma and No Other Associated Symptoms: The Importance of Genetic Testing and Establishing Follow-Up Policies2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Establishment of human induced pluripotent stem cell lines, KMUGMCi006, from a patient with Tuberous sclerosis complex (TSC) bearing mosaic nonsense mutations in the Tuberous sclerosis complex 2 (TSC2) gene2023

Author(s)

Journal Title

DOI

Ura Hiroki 浦大樹

浦大樹ウラヒロキ