Ohashi Nami 大橋南美

… Alternative Names

大橋南美オオハシナミ

Less

Researcher Number	90707051
Other IDs
Affiliation (Current)	2025: 昭和薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2017: 東京医科歯科大学, 生体材料工学研究所, 助教 2015: 東京医科歯科大学, 生体材料工学研究所, 助教
Review Section/Research Field	Except Principal Investigator Drug development chemistry
Keywords	Except Principal Investigator 2価結合型GPCRリガンド / 高次構造模倣型 / 二量体 / 2価型 / 二次構造 / 中分子創薬 / 医薬品開発 / ヒト免疫不全ウイルス / GPCR / CXCR4 … More / ステープルペプチド / がん / HIV / 環状ペプチド / ペプチドミメティック / 中分子 Less

Development of mid-size drugs based on peptidomimetic
- Principal Investigator
  
  TAMAMURA Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Tokyo Medical and Dental University

All 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Mid-Size Drugs Based on Peptides and Peptidomimetics: A New Drug Category2018
- Author(s)
  Tamamura H, Kobayakawa T, Ohashi N
- Total Pages
  100
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-15H04652
[Book] Peptide-derived mid-sized anti-HIV agents. Amino Acids, Peptides and Proteins2017
- Author(s)
  Ohashi N, Tamamura H
- Total Pages
  30
- Publisher
  The Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-15H04652
[Journal Article] Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-lactones as PKC Ligands2017
- Author(s)
  Nami Ohashi, Ryosuke Kobayashi, Wataru Nomura, Takuya Kobayakawa, Agnes Czikora, Brienna Herold, Nancy E. Lewin, Peter M. Blumberg, Hirokazu Tamamura
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 28 Issue: 8 Pages: 2135-2144
- DOI
  10.1021/acs.bioconjchem.7b00299
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01931, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-16J08904, KAKENHI-PROJECT-16K15139
[Journal Article] A minimally cytotoxic CD4 mimic as an HIV entry inhibitor2016
- Author(s)
  Takaaki Mizuguchi, Shigeyoshi Harada, Tomoyuki Miura, Nami Ohashi, Tetsuo Narumi, Hiromi Mori, Yu Irahara, Yuko Yamada, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 26 Issue: 2 Pages: 397-400
- DOI
  10.1016/j.bmcl.2015.11.103
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26105721, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-15H04870, KAKENHI-PROJECT-26670053, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16H04682, KAKENHI-PROJECT-15K08125, KAKENHI-PROJECT-16K01931
[Journal Article] Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.2016
- Author(s)
  Nami Ohashi1, Shigeyoshi Harada, Takaaki Mizuguchi1, Yu Irahara1, Yuko Yamada, Misato Kotani, Wataru Nomura, Shuzo Matsushita, Kazuhisa Yoshimura, Hirokazu Tamamura.
- Journal Title
  
  Chem Med Chem
  
  Volume: 19 Issue: 8 Pages: 940-946
- DOI
  10.1002/cmdc.201500590
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08125, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-15H04870, KAKENHI-PROJECT-26670053, KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K15139
[Journal Article] Trivalent Lignds for CXCR4 Bearing Polyproline Linkers Show Specific Recognition for Cells with Increased CXCR4 Expression.2015
- Author(s)
  Wataru Nomura, Taisuke Koseki, Nami Ohashi, Takaaki Mizuguchi & Hirokazu Tamamura
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 13 Issue: 32 Pages: 8734-8739
- DOI
  10.1039/c5ob00891c
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-26670053
[Journal Article] Anti-HIV Screening for Cell-Penetrating Peptides Using Chloroquine and Identification of Anti-HIV Peptides Derived from Matrix Proteins.2015
- Author(s)
  Takaaki Mizuguchi, Nami Ohashi, Wataru Nomura, Mao Komoriya, Chie Hashimoto, Naoki Yamamoto, Tsutomu Murakami & Hirokazu Tamamura
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 15 Pages: 4423-4427
- DOI
  10.1016/j.bmc.2015.06.020
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-26670053
[Journal Article] An In-cell Fluorogenic Tag-probe System for Protein Dynamics Imaging Enabled by Cell-Penetrating Peptides.2015
- Author(s)
  Wataru Nomura, Nami Ohashi, Atsumi Mori & Hirokazu Tamamura
- Journal Title
  
  Bioconjugate Chem.
  
  Volume: 26 Issue: 6 Pages: 1080-1085
- DOI
  10.1021/acs.bioconjchem.5b00131
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-26670053
[Presentation] CD4 Mimics for Enhancement of Activity of HIV Neutralizing Antibodies2017
- Author(s)
  Ohashi N, Harada S, Irahara Y, Ishida Y, Konno K, Kobayakawa T, Nomura W, Matsushita S, Yoshimura K, Tamamura H
- Organizer
  The 11th AFMC International Medicinal Chemistry Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04652

1. TAMAMURA Hirokazu (80217182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 野村渉 (80463909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 水口貴章 (30732557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. YOSHIMURA Kazuhisa

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MURAKAMI Tsutomu

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. NARUMI Tetsuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. HARADA Shigeyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohashi Nami 大橋 南美

大橋 南美 オオハシ ナミ

Research Projects

Research Products

Co-Researchers

Development of mid-size drugs based on peptidomimetic

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Mid-Size Drugs Based on Peptides and Peptidomimetics: A New Drug Category2018

Author(s)

Total Pages

Publisher

Data Source

[Book] Peptide-derived mid-sized anti-HIV agents. Amino Acids, Peptides and Proteins2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-lactones as PKC Ligands2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A minimally cytotoxic CD4 mimic as an HIV entry inhibitor2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trivalent Lignds for CXCR4 Bearing Polyproline Linkers Show Specific Recognition for Cells with Increased CXCR4 Expression.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-HIV Screening for Cell-Penetrating Peptides Using Chloroquine and Identification of Anti-HIV Peptides Derived from Matrix Proteins.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An In-cell Fluorogenic Tag-probe System for Protein Dynamics Imaging Enabled by Cell-Penetrating Peptides.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] CD4 Mimics for Enhancement of Activity of HIV Neutralizing Antibodies2017

Author(s)

Organizer

Data Source

Ohashi Nami 大橋南美

大橋南美オオハシナミ