Kikuchi Masataka 菊地正隆

Researcher Number	90722538
Other IDs
Affiliation (Current)	2025: 新潟大学, 脳研究所, 特任准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 新潟大学, 脳研究所, 特任准教授 2022 – 2023: 東京大学, 大学院新領域創成科学研究科, 特任准教授 2020 – 2021: 大阪大学, 医学系研究科, 特任准教授(常勤) 2018 – 2019: 大阪大学, 医学系研究科, 特任講師(常勤) 2016 – 2017: 大阪大学, 医学系研究科, 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 43060:System genome science-related / System genome science Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 51030:Pathophysiologic neuroscience-related / System genome science
Keywords	Principal Investigator アルツハイマー病 / ポリジェニックスコア / 疾患サブタイプ / サブタイピング / サブタイプ / ドラッグリポジショニング / 脳神経疾患 / 生体生命情報学 / マルチオミックス / 遺伝子ネットワーク / データベース … More Except Principal Investigator … More アルツハイマー病 / APOE２ / 長寿 / APOE2 / アミロイドβ / 認知症 / 解析アプリ / 連鎖不平衡 / ゲノム解析技術 / シーケンサ / データベース / 解析ソフトウェア / ヒト疾患関連変異 / マイクロアレイ / 次世代シーケンサ / ゲノム解析 Less

Pathway and Cell Type Specific Polygenic Risk Scoring for Alzheimer's DiseasePrincipal Investigator
- Principal Investigator
  
  菊地正隆
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Niigata University
アルツハイマー病保護因子APOE２多型の作用機序の解明と治療薬開発への応用
- Principal Investigator
  
  篠原充
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Center for Geriatrics and Gerontology
Development of a novel drug repositioning method considering Alzheimer's disease subtypesPrincipal Investigator
- Principal Investigator
  
  Kikuchi Masataka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  The University of Tokyo
  Osaka University
Study of two-step amyloid-beta accumulation in human brains
- Principal Investigator
  
  Shinohara Mitsuru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  National Center for Geriatrics and Gerontology
Multi-omics database for Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Kikuchi Masataka
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  System genome science
- Research Institution
  Osaka University
Development of an integrated data-processing environment for disease-related genome analysis
- Principal Investigator
  
  NAKAYA Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  System genome science
- Research Institution
  Osaka University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] The clinical application of optimized AT(N) classification in Alzheimer’s clinical syndrome (ACS) and non-ACS conditions2023
- Author(s)
  Kasuga Kensaku、Tsukie Tamao、Kikuchi Masataka、Tokutake Takayoshi、Washiyama Kazuo、Shimizu Soichiro、Yoshizawa Hiroshi、Kuroha Yasuko、Yajima Ryuji、Mori Hiroshi、Arakawa Yasuaki、Onda Kiyoshi、Miyashita Akinori、Onodera Osamu、Iwatsubo Takeshi、Ikeuchi Takeshi
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 127 Pages: 23-32
- DOI
  10.1016/j.neurobiolaging.2023.03.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-23K18262, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-21H03537
[Journal Article] Retinoic Acid Deficiency Underlies the Etiology of Midfacial Defects2022
- Author(s)
  Wu Y.、Kurosaka H.、Wang Q.、Inubushi T.、Nakatsugawa K.、Kikuchi M.、Ohara H.、Tsujimoto T.、Natsuyama S.、Shida Y.、Sandell L.L.、Trainor P.A.、Yamashiro T.
- Journal Title
  
  Journal of Dental Research
  
  Volume: In press Issue: 6 Pages: 686-694
- DOI
  10.1177/00220345211062049
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21K10159
[Journal Article] Genetics of Alzheimer’s disease: an East Asian perspective2022
- Author(s)
  Miyashita Akinori、Kikuchi Masataka、Hara Norikazu、Ikeuchi Takeshi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 115-124
- DOI
  10.1038/s10038-022-01050-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07271, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21H03537
[Journal Article] Construction of prediction models for growth traits of soybean cultivars based on phenotyping in diverse genotype and environment combinations2022
- Author(s)
  Manggabarani Andi Madihah、Hashiguchi Takuyu、Hashiguchi Masatsugu、Hayashi Atsushi、Kikuchi Masataka、Mustamin Yusdar、Bamba Masaru、Kodama Kunihiro、Tanabata Takanari、Isobe Sachiko、Tanaka Hidenori、Akashi Ryo、Nakaya Akihiro、Sato Shusei
- Journal Title
  
  DNA Research
  
  Volume: 29 Issue: 4
- DOI
  10.1093/dnares/dsac024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15778
[Journal Article] Different AT(N) profiles and clinical progression classified by two different N markers using total tau and neurofilament light chain in cerebrospinal fluid2022
- Author(s)
  Kasuga Kensaku、Kikuchi Masataka、Tsukie Tamao、Suzuki Kazushi、Ihara Ryoko、Iwata Atsushi、Hara Norikazu、Miyashita Akinori、Kuwano Ryozo、Iwatsubo Takeshi、Ikeuchi Takeshi、collaboration author: Masaki Ikeda
- Journal Title
  
  BMJ Neurology Open
  
  Volume: 4 Issue: 2 Pages: e000321-e000321
- DOI
  10.1136/bmjno-2022-000321
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-22K07511, KAKENHI-PROJECT-22K07549, KAKENHI-PROJECT-22H04961, KAKENHI-PROJECT-21H02844, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21H03537
[Journal Article] Identification of mild cognitive impairment subtypes predicting conversion to Alzheimer’s disease using multimodal data2022
- Author(s)
  Kikuchi M, Kobayashi K, Itoh S, Kasuga K, Miyashita A, Ikeuchi T, Yumoto E, Kosaka Y, Fushimi Y, Takeda T, Manabe S, Hattori S; Alzheimer's Disease Neuroimaging Initiative; Nakaya A, Kamijo K, Matsumura Y
- Journal Title
  
  Computational and Structural Biotechnology Journal
  
  Volume: 20 Pages: 5296-5308
- DOI
  10.1016/j.csbj.2022.08.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-20K07196, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-21H03537
[Journal Article] Genome-wide copy number variation analysis of hepatitis B infection in a Japanese population2021
- Author(s)
  Kikuchi M, Kobayashi K, Nishida N, Sawai H, Sugiyama M, Mizokami M, Tokunaga K, Nakaya A
- Journal Title
  
  Human Genome Variation
  
  Volume: 8 Issue: 1 Pages: 22-22
- DOI
  10.1038/s41439-021-00154-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-21K07997, KAKENHI-PROJECT-20K15778
[Journal Article] 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans2021
- Author(s)
  Van der Meer D, Kikuchi M (70 in 143 authors), Boen R.
- Journal Title
  
  Translational Psychiatry
  
  Volume: 11 Issue: 1 Pages: 182-182
- DOI
  10.1038/s41398-021-01213-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18KT0022, KAKENHI-PUBLICLY-20H04860
[Journal Article] Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the ENIGMA working groups on CNVs2021
- Author(s)
  Sonderby I, ... , for the ENIGMA-CNV Working Group (Kikuchi M (16 in 31 authors)) and ENIGMA 22q11.2 Deletion Syndrome Working Group.
- Journal Title
  
  Human Brain Mapping
  
  Volume: NA Issue: 1 Pages: 300-328
- DOI
  10.1002/hbm.25354
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611
[Journal Article] Methylation Analysis in Monozygotic Twins With Treatment-Resistant Schizophrenia and Discordant Responses to Clozapine.2021
- Author(s)
  Kikuchi M, Nakazawa T, Kinoshita M, Yamamori H, Yasuda Y, Fujimoto M, Hashimoto R, Numata S
- Journal Title
  
  Frontiers in Psychiatry
  
  Volume: 12 Pages: 734606-734606
- DOI
  10.3389/fpsyt.2021.734606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-20K07945, KAKENHI-PROJECT-20K15778
[Journal Article] Synergistic role of retinoic acid signaling and Gata3 during primitive choanae formation2021
- Author(s)
  Kurosaka Hiroshi、Mushiake Jin、Saha Mithun、Wu Yanran、Wang Qi、Kikuchi Masataka、Nakaya Akihiro、Yamamoto Sayuri、Inubushi Toshihiro、Koga Satoshi、Sandell Lisa L、Trainor Paul A、Yamashiro Takashi
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 30 Issue: 24 Pages: 2383-2392
- DOI
  10.1093/hmg/ddab205
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-20K15778
[Journal Article] Upregulated expression of a subset of genes in APP;ob/ob mice: Evidence of an interaction between diabetes‐linked obesity and Alzheimer’s disease2021
- Author(s)
  Shinohara Mitsuru、Kikuchi Masataka、Onishi‐Takeya Miyuki、Tashiro Yoshitaka、Suzuki Kaoru、Noda Yasuhiro、Takeda Shuko、Mukouzono Masahiro、Nagano Seiichi、Fukumori Akio、Morishita Ryuichi、Nakaya Akihiro、Sato Naoyuki
- Journal Title
  
  FASEB BioAdvances
  
  Volume: - Issue: 5 Pages: 323-333
- DOI
  10.1096/fba.2020-00151
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-18H02725, KAKENHI-PROJECT-20K15778
[Journal Article] Artificial intelligence-based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer’s disease2021
- Author(s)
  Tsuji, S., Hase, T., Yachie-Kinoshita, A., Nishino, T., Ghosh, S., Kikuchi, M., Shimokawa, K., Aburatani, H., Kitano, H. & Tanaka, H.
- Journal Title
  
  Alzheimer's Research & Therapy
  
  Volume: 13, 92 Issue: 1
- DOI
  10.1186/s13195-021-00826-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06107, KAKENHI-PROJECT-20K15778
[Journal Article] Polygenic Architecture of Human Neuroanatomical Diversity2020
- Author(s)
  Biton Anne, Kikuchi Masataka (13 of 25 authors), Toro Roberto
- Journal Title
  
  Cerebral Cortex
  
  Volume: 30 Issue: 4 Pages: 2307-2320
- DOI
  10.1093/cercor/bhz241
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15049, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-19H05467, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18KT0022
[Journal Article] The genetic architecture of the human cerebral cortex2020
- Author(s)
  Grasby L Katrina, Kikuchi Masataka (79 of 348 authors), Medland E Sarah
- Journal Title
  
  Science
  
  Volume: 367
- DOI
  10.1101/399402
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15049
[Journal Article] Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition2020
- Author(s)
  Writing Committee for the ENIGMA-CNV Working Group、van der Meer Dennis、S?nderby Ida E.、Kaufmann Tobias、Walters G. Bragi、...、Fukunaga Masaki、....、Hashimoto Ryota、...、Dale Anders M.、Djurovic Srdjan、Agartz Ingrid、Westlye Lars T.、Stefansson Hreinn、Stefansson K、Thompson Paul M.、Andreassen Ole A.
- Journal Title
  
  JAMA Psychiatry
  
  Volume: 77 Issue: 4 Pages: 420-420
- DOI
  10.1001/jamapsychiatry.2019.3779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03305, KAKENHI-PROJECT-17K15049, KAKENHI-PROJECT-20K15778, KAKENHI-PROJECT-20H03611, KAKENHI-PROJECT-18KT0022
[Journal Article] Disruption of a RAC1-centred network is associated with Alzheimer's disease pathology and causes age-dependent neurodegeneration.2020
- Author(s)
  Masataka Kikuchi, Michiko Sekiya, Norikazu Hara, Akinori Miyashita, Ryozo Kuwano, Takeshi Ikeuchi, Koichi M Iijima, Akihiro Nakaya
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 29 Issue: 5 Pages: 817-833
- DOI
  10.1093/hmg/ddz320
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07517, KAKENHI-PROJECT-17K15049
[Journal Article] Perturbed development of cranial neural crest cells in association with reduced sonic hedgehog signaling underlies the pathogenesis of retinoic-acid-induced cleft palate2019
- Author(s)
  Wang Qi、Kurosaka Hiroshi、Kikuchi Masataka、Nakaya Akihiro、Trainor Paul A.、Yamashiro Takashi
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 12 Issue: 10 Pages: 040279-040279
- DOI
  10.1242/dmm.040279
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03858, KAKENHI-PROJECT-17K15049
[Journal Article] 特集認知症と遺伝アルツハイマー病リスク因子としてのアポリポ蛋白E42019
- Author(s)
  菊地正隆、中谷明弘
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 71 Issue: 10 Pages: 1053-1060
- DOI
  10.11477/mf.1416201404
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2019-10-01
- Data Source
  KAKENHI-PROJECT-17K15049
[Journal Article] Enhancer variants associated with Alzheimer’s disease affect gene expression via chromatin looping2019
- Author(s)
  Kikuchi Masataka、Hara Norikazu、Hasegawa Mai、Miyashita Akinori、Kuwano Ryozo、Ikeuchi Takeshi、Nakaya Akihiro
- Journal Title
  
  BMC Medical Genomics
  
  Volume: 12 Issue: 1 Pages: 128-128
- DOI
  10.1186/s12920-019-0574-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15049
[Journal Article] Genome-wide Association Analysis of Eye Movement Dysfunction in Schizophrenia.2018
- Author(s)
  Kikuchi M, Miura K, Morita K, Yamamori H, Fujimoto M, Ikeda M, Yasuda Y, Nakaya A, uHashimoto R.
- Journal Title
  
  Sci Rep
  
  Volume: 8(1) Issue: 1 Pages: 12347-12347
- DOI
  10.1038/s41598-018-30646-9
- NAID
  120006549303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0022, KAKENHI-PROJECT-17K10300, KAKENHI-PROJECT-17K15049, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-16K07222
[Journal Article] Enhancer variants associated with Alzheimer's disease affect gene expression via chromatin looping2018
- Author(s)
  Kikuchi M, Hara N, Hasegawa M, Miyashita A, Kuwano R, Ikeuchi T, and Nakaya A
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/426312
- Open Access
- Data Source
  KAKENHI-PROJECT-16K07222
[Journal Article] Effect of Clozapine on DNA Methylation in Peripheral Leukocytes from Patients with Treatment-Resistant Schizophrenia.2017
- Author(s)
  Kinoshita M, Numata S, Tajima A, Yamamori H, Yasuda Y, Fujimoto M, Watanabe S, Umehara H, Shimodera S, Nakazawa T, Kikuchi M, Nakaya A, Hashimoto H, Imoto I, Hashimoto R, Ohmori T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 18 Issue: 3 Pages: 632-632
- DOI
  10.3390/ijms18030632
- NAID
  120006535029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01286, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26461719, KAKENHI-PROJECT-15K14963, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K19725, KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-15K09809
[Journal Article] Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine.2017
- Author(s)
  Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R.
- Journal Title
  
  Schizophr Res.
  
  Volume: 181 Pages: 75-82
- DOI
  10.1016/j.schres.2016.10.012
- NAID
  120007037467
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01286, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-15H04645, KAKENHI-PROJECT-16H05375, KAKENHI-PROJECT-15K14963, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-15K19725, KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-16K08269, KAKENHI-PROJECT-16K15125, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-15K09865
[Journal Article] バイオインフォマティクスを活用したアルツハイマー病病態解析2017
- Author(s)
  菊地正隆、中谷明弘
- Journal Title
  
  分子精神医学
  
  Volume: 17 Pages: 71-77
- Data Source
  KAKENHI-PROJECT-17K15049
[Journal Article] アルツハイマー病の遺伝学的リスク2017
- Author(s)
  宮下哲典、原範和、春日健作、菊地正隆、中谷明弘、池内健
- Journal Title
  
  老年精神医学
  
  Volume: 28 Pages: 754-764
- Data Source
  KAKENHI-PROJECT-17K15049
[Journal Article] Identification of core gene networks and hub genes associated with progression of nonalcoholic fatty liver disease by RNA sequencing2017
- Author(s)
  Hotta K, Kikuchi M, Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Kessoku T, Kobayashi K, Yoneda, M, Imajo K, Tomeno W, Nakaya A, Suzuki Y, Saito S, and Nakajima A
- Journal Title
  
  Hepatology Research
  
  Volume: 印刷中 Issue: 13 Pages: 1445-1448
- DOI
  10.1111/hepr.12877
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-16K09781
[Journal Article] 増大特集あしたのアルツハイマー病治療アルツハイマー病のバイオインフォマティクス解析2017
- Author(s)
  菊地正隆、中谷明弘
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 69 Issue: 7 Pages: 835-842
- DOI
  10.11477/mf.1416200828
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2017-07-01
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] Identification of mild cognitive impairment subtypes predicting conversion to Alzheimer’s disease using a heterogeneous mixture learning2022
- Author(s)
  菊地正隆
- Organizer
  International Symposium on Artificial Life and Robotics（AROB）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] Polygenic risk effect of Alzheimer’s disease in the Japanese population2022
- Author(s)
  Masataka Kikuchi
- Organizer
  4th Japan-UK Neuroscience Symposium 2022
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] シングルセルオミックスデータを用いたアルツハイマー病の層別化解析2022
- Author(s)
  菊地正隆
- Organizer
  第 95 回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] マルチモーダルデータとゲノミクスに基づいた認知症サブタイピング解析2022
- Author(s)
  菊地正隆
- Organizer
  第11回生命医薬情報学連合大会
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] AI技術を活用した認知症の発症リスク予測とその不均一性の理解2021
- Author(s)
  菊地正隆
- Organizer
  第94回生化学会大会シンポジウム
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] 認知症ポリジェニック解析による病態の層別化2021
- Author(s)
  菊地正隆
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] 異種混合学習を用いたアルツハイマー病発症予測解析2020
- Author(s)
  菊地正隆，小林香織，湯本英二，伏見泰人，武田理宏，真鍋史朗，松村泰志，上條憲一，中谷明弘
- Organizer
  第24回日本医療情報学会春季学術大会
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] Polygenic analysis of Alzheimer’s disease in a Japanese population2020
- Author(s)
  Masataka Kikuchi
- Organizer
  Asian Forum on Alzheimer's Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] 軽度認知障害のデータドリブンなサブタイピングおよびアルツハイマー病発症予測2020
- Author(s)
  菊地正隆、小林香織、春日健作、宮下哲典、池内健、湯本英二、伏見泰人、武田理宏、真鍋史朗、上條憲一、松村泰志
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] Polygenic analysis of Alzheimer’s disease in a Japanese population2020
- Author(s)
  Masataka Kikuchi, Akinori Miyashita, Norikazu Hara, Daichi Shigemizu, Kouichi Ozaki, Shumpei Niida, Takechi Ikeuchi, Akihiro Nakaya
- Organizer
  The Alzheimer's Association International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] An application of heterogeneous mixture learning for mild cognitive impairment subtyping2020
- Author(s)
  Masataka Kikuchi, Kaori Kobayashi, Kensaku Kasuga, Akinori Miyashita, Takeshi Ikeuchi, Eiji Yumoto, Yasuto Fushimi, Toshihiro Takeda, Shirou Manabe, for the Alzheimer’s Disease Neuroimaging Initiative, Kenichi Kamijo, Yasushi Matsumura
- Organizer
  11th Biennial Conference of the Asia-Pacific Association for Medical Informatics (APAMI 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] アルツハイマー病マルチオミックスデータを用いたシステム生物学的研究2020
- Author(s)
  菊地正隆
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K15778
[Presentation] 日本人におけるAPOEのコモン・レアバリアント解析2019
- Author(s)
  宮下哲典,原範和,春日健作,LIU Lixin,樋口陽,ZHU Bin,月江珠緒,石黒敬信,村上涼太,菊地正隆,中谷明弘,尾崎浩一,新飯田俊平,赤澤宏平,桑野良三,桑野良三,岩坪威,岩坪威,池内健
- Organizer
  日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] 日本人集団におけるアルツハイマー病ポリジェニック解析2019
- Author(s)
  菊地正隆,宮下哲典,原範和,重水大智,尾崎浩一,新飯田俊平,池内健,中谷明弘
- Organizer
  日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] ヒト死後脳におけるAPP・APOEの遺伝子発現解析2019
- Author(s)
  LIU Lixin,宮下哲典,村上涼太,ZHU Bin,原範和,菊地正隆,月江珠緒,樋口陽,春日健作,中谷明弘,赤津裕康,柿田明美,村山繁雄,池内健
- Organizer
  日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] Polygenic analyses of Alzheimer's disease in Japanese population2019
- Author(s)
  Masataka Kikuchi, Akinori Miyashita, Takechi Ikeuchi, Akihiro Nakaya
- Organizer
  Alzheimer's Association International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] Polygenic analysis of Alzheimer’s disease in a Japanese population2019
- Author(s)
  Masataka Kikuchi, Akinori Miyashita, Norikazu Hara, Daichi Shigemizu, Kouichi Ozaki, Shumpei Niida, Takechi Ikeuchi, Akihiro Nakaya
- Organizer
  The 13th International Workshop on Advanced Genomics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] アルツハイマー病の原因遺伝子と感受性遺伝子:我々の取り組みと国内外の最新情報2018
- Author(s)
  宮下哲典, 原範和, 菊地正隆, 月江珠緒, 春日健作, 中谷明弘, 池内健
- Organizer
  日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] 染色体高次構造を介したアルツハイマー病リスクバリアントの影響2018
- Author(s)
  菊地正隆, 原範和, 長谷川舞衣, 宮下哲典, 桑野良三, 池内健, 中谷明弘
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07222
[Presentation] APOE遺伝型はAPPの遺伝子発現量に影響を及ぼすか?:ヒト死後脳における検証2018
- Author(s)
  村上涼太, 朱斌, 原範和, 菊地正隆, 月江珠緒, 春日健作, 宮下哲典, 中谷明弘, 赤津裕康, 柿田明美, 村山繁雄, 池内健
- Organizer
  日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] ポリジェニックハザードスコアを用いたアルツハイマー病発症年齢解析2018
- Author(s)
  菊地正隆, 宮下哲典, 池内健, 中谷明弘
- Organizer
  第37回認知症学会
- Data Source
  KAKENHI-PROJECT-16K07222
[Presentation] Enhancer variants associated with Alzheimer's disease affect gene expression via chromatin looping2018
- Author(s)
  Masataka Kikuchi
- Organizer
  The Asian Forum on Alzheimer’s and Dementia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] ポリジェニックハザードスコアを用いたアルツハイマー病発症年齢解析2018
- Author(s)
  菊地正隆, 宮下哲典, 池内健, 中谷明弘
- Organizer
  日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15049
[Presentation] The prediction method of deleterious variants for Alzheimer's disease using chromatin higher-order structure2017
- Author(s)
  Kikuchi M, Hara N, Hasegawa M, Miyashita A, Kuwano R, Ikeuchi T, and Nakaya A
- Organizer
  The 7th BRI International Symposium 2017
- Place of Presentation
  Brain Research Institute, Niigata University
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-16K07222
[Presentation] エクソーム解析基盤を用いた日本人変異解析における解析手法の検証と可視化2017
- Author(s)
  小林香織, 今井敦子, 山崎悟, 菊地正隆, 足尾勉, 上條憲一, 松村泰志, 中谷明弘
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07222
[Presentation] 日本人集団におけるB型肝炎の全ゲノムコピー数多型解析2017
- Author(s)
  菊地正隆, 小林香織, 澤井裕美, 西田奈央, 杉山真也, 溝上雅史, 徳永勝士, 中谷明弘
- Organizer
  日本人類遺伝学会第62回大会
- Data Source
  KAKENHI-PROJECT-16K07222
[Presentation] アルツハイマー病感受性領域が近接する染色体領域の同定2016
- Author(s)
  菊地正隆, 原範和, 長谷川舞衣, 宮下哲典, 桑野良三, 池内健, 中谷明弘
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07222
[Presentation] Identification of chromosomal regions interacting with susceptibility loci for Alzheimer’s disease2016
- Author(s)
  Kikuchi M, Hara N, Hasegawa M, Miyashita A, Kuwano R, Ikeuchi T, and Nakaya A
- Organizer
  Alzheimer's Association International Conference (AAIC) 2016
- Place of Presentation
  Toronto, Canada
- Year and Date
  2016-07-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07222

1. Shinohara Mitsuru (60800521)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 齊藤祐子 (60344066)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAKAYA Akihiro (60301149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
4. 岡崎敦子 (70761691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 赤津裕康 (00399734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 村山繁雄 (50183653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大塚礼 (00532243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 笹栗弘貴 (10783053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西田裕紀子 (60393170)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐藤亜希子 (80800979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小木曽昇 (40638350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 原範和 (00775918)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 池内健 (20372469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KOBAYASHI kaori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. NAKAZAWA Takanobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. INUBUSHI Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. IKEDA Yoshio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. MICHIKO Sekiya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 山城隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 黒坂寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. 橋本亮太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 宮下哲典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 今井敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 辻真吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 池田将樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 福永雅喜

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kikuchi Masataka 菊地 正隆

Research Projects

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Co-Researchers

Pathway and Cell Type Specific Polygenic Risk Scoring for Alzheimer's DiseasePrincipal Investigator

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アルツハイマー病保護因子APOE２多型の作用機序の解明と治療薬開発への応用

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Development of a novel drug repositioning method considering Alzheimer's disease subtypesPrincipal Investigator

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Study of two-step amyloid-beta accumulation in human brains

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Multi-omics database for Alzheimer's diseasePrincipal Investigator

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Development of an integrated data-processing environment for disease-related genome analysis

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[Journal Article] The clinical application of optimized AT(N) classification in Alzheimer’s clinical syndrome (ACS) and non-ACS conditions2023

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[Journal Article] Retinoic Acid Deficiency Underlies the Etiology of Midfacial Defects2022

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[Journal Article] Genetics of Alzheimer’s disease: an East Asian perspective2022

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[Journal Article] Construction of prediction models for growth traits of soybean cultivars based on phenotyping in diverse genotype and environment combinations2022

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[Journal Article] Different AT(N) profiles and clinical progression classified by two different N markers using total tau and neurofilament light chain in cerebrospinal fluid2022

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[Journal Article] Identification of mild cognitive impairment subtypes predicting conversion to Alzheimer’s disease using multimodal data2022

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[Journal Article] Genome-wide copy number variation analysis of hepatitis B infection in a Japanese population2021

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[Journal Article] 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans2021

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Kikuchi Masataka 菊地正隆

[Journal Article] 特集認知症と遺伝アルツハイマー病リスク因子としてのアポリポ蛋白E42019