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SHIRAHAMA Haruhisa  白濱 晴久

ORCIDConnect your ORCID iD *help
Researcher Number 00000802
Affiliation (based on the past Project Information) *help 1995 – 1998: 関西学院大学, 理学部, 教授
1987 – 1993: Hokkaido University Fac.of Sci., 理学部, 教授
1986: 北海道大学, 理学部, 助教授
Review Section/Research Field
Principal Investigator
天然物有機化学 / Bioorganic chemistry
Except Principal Investigator
天然物有機化学 / Bioorganic chemistry / 広領域
Keywords
Principal Investigator
アクロメリン酸 / オオワライタケ / ドクササコ / 神経毒 / ジムノピリン / カイノイド / 脱分極活性 / acromelic acid / グルタメート受容体 / キラルHMGA半エステル … More / キラルなβ-ラクトン / HMGA / オリゴイソプレノイド / 神経興奮性アミノ酸 / キノコ / ギムノピリン / アクロメリン酸類縁体 / Lipid peroxilation inhibitor / Suillus greevillei / Gymnopolin / Gymnopilus spectalilis / neuroexcitatory substonces / New synthetic method of kainoids / New kainoid / Clito eybe acromeralga / 光ジールズアルダー反応 / プラストキノン / グルタメ-ト / 神経興奮性アシノ酸 / 過酸化脂質生成阻害活性 / 担子菌 / 過酸化脂質生成阻害 / 過酸化脂質生成阻害物質 / ハナイグチ / 神経興奮性物質 / カイノイドの新合成法 / 新カイノイド / 2-heptenyl-3-methyl-4-quinolinol / 2-nonenyl-3-methyl-4-quinolinol / phenazine-1-carboxylic acid / chlororaphine / hemipyocyanine / ポリオキシ-ゲラニルゲラニルベンゼン / フェナジンー1ーカルボン酸 / 2ー(0ーヒドロキシフェンル)ー4ーホルミルチアゾール / シウルスーグレビレイ / P.エルギノーサ / P.セパシア / 4-ジオキシ-6-ゲラニルゲラニルベンゼン / 1-アセトキシ-2 / 2-ヘプテニル-3-メチル-4-キノリノール / 2-ノネニル-3-メチル-4-キノリノール / フェナジン-1-カルボン酸 / クロラフィン / ヘミピオシアニン / a new method of pyridine synthesis / potentiation of glutamate response / neurotransmittance / α-ピリドンの新合成法 / ピリジン環の新合成法 / アクロメリン酸(B)の合成 / アクロメリン酸(A)の合成の合成 / 新ピリジン合成法アクロメリン酸の全合成 / グルタメート応答増強 / 神経伝達物質 / HMGA beta-lactone / HMGA ester / gymnopilin / depolarizing activity / conformation / poisonous mushroom / kainoid / ヒカゲシビレタケ / トリフロロアセトフェノン / ベンジルラジカル / ラジカルによるC-C結合形成 / ピロリジン環形成反応 / Conformational analysis / Carboxycyclopentylglycine / Carboxycyclopropylglycine / 4-phenyl-3-dehydroproline / Configuration of C_4 side chain in kainoids / Glutamate receptor / Acromelic acid / ピロリジン環の効率的形成 / 光照射下のジールズアルダー反応 / アクロメリン酸B / 立体配座解析 / カルボキシシクロペンチルグリシン / カルボキシシクロプロピルグリシン / 4-フェニル-3-デヒドロプロリン / カイノイドC_4側鎖の立体配座 / Allelopasic substances / Antifeedant / Cell decision inhibitors / Carcinogenic promotors / Cell grouth control factors / Neurotrophic compounds / Isolation of neurotoxins / Neurotoxins / 発癌性物質 / 発癌プロモ-タ- / 神経毒の合成 / 他感作用物質 / 摂食阻害物質 / 卵割阻害活性物質 / 発癌プロモーター / 細胞生長制御物質 / 神経突起伸展作用物質 / 神経毒の単離 / SEM基の除去条件 / 5-エンーl-オールのシャープレス酸化 / チルシフェロール 23-アセタート / チルシフェロール / 全合成 / アクロメリン酸誘導体 / 神経興奮作用 / チルシフェロールの合成 / 環化反応 / 水銀塩 / フムレン / ケタール化 / タキソール / メトキシメチルアミド / ラジカル反応 / 立体選択的ピロリジン環形成 / (5+2)反応 / 立体配置選択性 / HMPAの溶媒効果 / ケチルラジカル / ヨウ化サマリュウム / タキソ-ル / ケチルラジカル環化反応 / ヨウ化サマリウム(II) / ビニグロール / グラヤノトキシン / ジテルペン / アクロメリン酸生合成中間体 / カイノイドの立体化学 / 立体配置制限 / コンホメ-ション認識 / カイネ-ト型受容体 / グルタメ-ト受容体 / ピロリジン‐2,3‐ジカルボン酸 / 神経伝達機能 / 毒物質 / ピロ-ルカルボン酸 / 立体選択的アリ-ル化 / 立体選択的ピロリジン成合法 / 光ジ-ルズアルダ-反応 / 光エノル化 … More
Except Principal Investigator
Intramolecular Stacking / Palytoxin / Polyprenol / Active Substance / Biorhythm / Biogenetic Pathway / Biosynthesis / Glycinoeclepin A / 花色素 / 生合成前駆体合成 / 就眠運動 / 酵素 / 分子内スタッキング / パリトキシン / ポリプレノ-ル / 活性物質 / バイオリズム / 生合成推定経路 / 生合成 / グリシノエクレピンA / Glycolipid / Defensive Substance / Antitumor Compound / DNA Cleavage Mechanism / Carcinogenic Substance / Marine Natural Product / Terpenoid Dialdehyde / 膜透過 / 抗酸化性天然物質 / 抗腫瘍性天然物質 / DNA切断分子機構 / ワラビ発癌物質 / 神経興奮性物質 / 海洋天然物質 / 複合糖質 / DNA切断機構 / 抗腫瘍性物質 / 発癌物質 / 捕食防御物質 / シガテラ毒 / 海産天然物 / テルペノイドジアルデヒド / Fluorescent substrate / Non-RI / Detection of nucleic acid / 蛍光基質 / 非RI / 核酸検出法 / Peptide / Secosteroid / Iridoid / Alkaloid / Terpenoid / Total synthesis / Structural determination / Biologically active substance / 構造決定 / 全合成 / ペプチド / ステロイド / イリドイド / アルカロイド / テルペノイド / 生体作用物質 / Naチャネル / アクロメリン酸 / グルタミン酸阻害 / アセチルコリン受容体 / モルヒネアナログ / 脳ANF / PHIボンベシン / 神経ペプチド / マストパラン Less
  • Research Projects

    (23 results)
  • Co-Researchers

    (41 People)
  •  ヒト細胞に強く作用する化合物の合成Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kwansei Gakuin University
  •  タキソ-ルの全合成Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kwansei Gakuin University
  •  神経系に作用するキノコ毒の不斉合成Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kwansei Gakuin University
  •  Structure Determination, Synthesis and Biological Activity of Neuroactive CompoundsPrincipal Investigator

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Kwansei Gakuin University
  •  生理活性ジテルペン類の高効率的キラル合成Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  COMPREHENSIVE RESEARCH TOWARD THE ELUCIDATION OF BIOLOGICAL ACTIVITIES OF NATURAL ORGANIC COMPOUNDS

    • Principal Investigator
      ISOE Sachihiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      OSAKA CITY UNIVERSITY
  •  担子菌より得られる生体内特異反応物質の構造解析、合成と機能発現Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  DEVELOPMENT OF POTENT ACTIVE COMPOUNDS WORKING ON NEUROTRANSMIT ORGANPrincipal Investigator

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      天然物有機化学
    • Research Institution
      Hokkaido University
  •  神経伝達機能をもつアミノ酸の合成と生体内作用Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  担子菌より得られる生体内特異反応物質の構造解析、合成と機能発現Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  ORGANIC CHEMISTRY OF THE BIOSYSTEM CONTROL SUBSTANCESPrincipal Investigator

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      天然物有機化学
    • Research Institution
      HOKKAIDO UNIVERSITY,(FACULTY OF SCIENCE)
  •  神経伝達機能をもつアミノ酸の合成と生体内作用Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  担子菌より得られる生体内特異反応物質の構造解析、合成と機能発現Principal Investigator

    • Principal Investigator
      白濱 晴久
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  A novel fluorescent method for detection of subpicogram quantities of nucleic acids

    • Principal Investigator
      HORI Hiroshi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      広領域
    • Research Institution
      Hokkaido University
  •  Multilateral Studies on Biologically Active Natural Substances

    • Principal Investigator
      UDA Hisashi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      天然物有機化学
    • Research Institution
      Tohoku University
  •  神経伝達物質の化学的研究

    • Principal Investigator
      中嶋 暉躬
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      The University of Tokyo
  •  Studies on Biosynthetic Mechanisms of Biologically Active Subsatnces and Their Applications

    • Principal Investigator
      MURAI Akio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      天然物有機化学
    • Research Institution
      Hokkaido University
  •  Isolation, Structural Determination and Synthesis of Biologically Active Substances Produced by FungiPrincipal Investigator

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      天然物有機化学
    • Research Institution
      Hokkaido University
  •  新カイノイドの化学合成による伝達物質と受容体との関係解明Principal Investigator

    • Principal Investigator
      白浜 晴久
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Hokkaido University
  •  有機水銀化合物の特性を利用する炭素環および複素環天然物の合成Principal Investigator

    • Principal Investigator
      白浜 晴久
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Hokkaido University
  •  Studies on the inhibitors from plant pathogens produced by soil germsPrincipal Investigator

    • Principal Investigator
      SHIRAHAMA Haruhisa, 白浜 晴久
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      天然物有機化学
    • Research Institution
      Hokkaido University
  •  有機水銀化合物の特性を利用する炭素環および複素環天然物の合成Principal Investigator

    • Principal Investigator
      白浜 晴久
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Hokkaido University
  •  Synthesis of accromelic acids and their derivativesPrincipal Investigator

    • Principal Investigator
      SHIRAHAMA Haruhisa
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      天然物有機化学
    • Research Institution
      Hokkaido University
  • 1.  TOKOROYAMA Takashi (90046938)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  HIRAMA Masahiro (30165203)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  MATSUDA Fuyuhiko (10219446)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  SHINOZAKI Haruhiko (20109945)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YANAGIYA Mitsutoshi (20000846)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  YAMADA Kiyoyuki (90022540)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  KAKISAWA Hiroshi (50015492)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KUSUMOTO Syouichi (30028253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  ISOBE Minoru (00023466)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  YAMAMURA Syosuke (40076708)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TACHIBANA Kazuo (70142081)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  MURAI Akio (20000838)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  SUGA Takayuki (00033811)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  松本 毅 (00000711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  中嶋 暉躬 (50012597)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  宗像 英輔 (60072766)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  山中 宏 (40004551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  矢内原 昇 (80046250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  井村 裕夫 (10025570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  UDA Hisashi (40006292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HORI Hiroshi (40000814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  YOSHIDA Kiyohito (40210687)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YOSHIDA Michihiro (60001765)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  高木 信夫 (20001852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OHFUNE Yasufumi (20142078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  ISOE Sachihiko (90046946)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  楠見 武徳 (70015882)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  越智 雅光 (40036562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  中山 充 (20033821)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  林 雄二 (40046917)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  児玉 三明 (30004378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  上江田 捷博 (10145550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  上村 大輔 (00022731)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  奥村 保明 (20021933)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  加藤 忠弘 (20004319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  加藤 紀元 (00006305)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  SHIZURI Yoshikazu (90135294)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  SANKAWA Ushio (60012613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  OGURA Kyozo (80006303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  丹羽 治樹 (20135297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  高杉 光雄 (70000833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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