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KONNO Tasuke  今野 多助

ORCIDConnect your ORCID iD *help
Researcher Number 00004846
Affiliation (based on the past Project Information) *help 1998: Institute of Development, Aging and Cancer, Department of Pediatric Oncology Toh, 加齢医学研究所・発達病態研究分野, 前教授
1993 – 1997: 東北大学, 加齢医学研究所, 教授
1996: 東北大学, 加齢医学研究所, 助手
1987 – 1992: Research Institute for Tuberculosis and Cancer, Tohoku University, 抗酸菌病研究所, 教授
1989: 東北大学, 抗酸菌病研所, 教授
1988: 東北大学, 抗酸菌病 研究所, 教授
1986: 東北大, 抗酸菌病研究所, 教授
Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Pediatrics / 内科学一般 / Immunology
Keywords
Principal Investigator
LFA-1 / 骨髄移植 / HLA不適合 / monoclonal antibody / HLA-mismatch / graft rejection / bone marrow transplantation / モノクローナル抗体 / CD_<18> / CD_<11>a … More / HLA不一致 / 単クロ-ン抗体 / 移植片拒絶 / LFAー1 / NK activity / flow cytometry / I cell-depleted immunodeficiency / histoincompability / HLA-haplotype / Bone marrow transplantation / 白血病 / リンパ球膜分化抗原 / HLA / 寛容 / NK活性 / T細胞除去 / フローサイトメトリー / 免疫不全症 / 組織適合成 / HLAハプロタイプ / enzyme-linked immunosrobent assay / mouse monoclonal antibody / LFA-1 antibody / anti-CD11a / GVHD / HLA-nonidentical dorno / allogeneic BMT / T細胞 / リンパ球芽球化反応 / 酵素免疫法(ELISA) / 骨髓移植 / 同権骨髄移植 / ELISA法 / マウスモノクロ-ナル抗体 / 抗LFAー1抗体 / 移植片対宿主病 / HLA不適合ドナ- / 同種骨髄移植 / CD34陽性細胞 / T-ALL / GATA転写因子 / 小児白血病 … More
Except Principal Investigator
IgD / WASP / アポトーシス / レトロウイルスベクター / p47-phox / gp91-phox / ABL / BCR / シグナル伝達 / XSCID / HEMATOPOIETIC STEM CELLS / 造血幹細胞 / GM-CSF / Precursor B cell line / congenital agammaglobulinemia / 表面マーカー / プレBリンパ芽球様細胞株 / EBウイルス / K+入鎖産生細胞クローン / K+λ産生細胞クローン / 細胞クローニング / モノクローナル抗体 / B細胞関連抗原 / Bリンパ芽球様細胞株 / 先天性無ガンマグロブリン血症 / retrovirus vector / NK cell / gammac chain / acute GVHD / interleukin-15 / X連鎖重症複合免疫不全症 / リーダー配列 / NK細胞 / γc鎖 / 急性移植片対宿主病 / インターロイキン15 / Signal Transduction / Integrins / Adhesion molecule / Cell line / Neuroblastoma / インターフェロンα / インテグリン / 細胞接着分子 / 細胞株 / 神経芽細胞腫 / mouse anti-WASP monoclonal antibody / carrier detection / gene diagnosis / Wiskott-Aldrich syndrome / Wiskott-aldrich症候群 / マウス抗WASP単クローン抗体 / 保因者診断 / 遺伝子診断 / Wiskott-Aldrich症候群 / phagocyte / beta-actin / eosinophil / superoxide / neutrophil / Chronic granulomatous disease / 遺伝性疾患 / 細胞内アクチン異常症 / 白血球粘着不全症 / CGD / 高IgE症候群 / β-アクチン / シトクロム / 食細胞 / βアクチン / 好酸球 / 活性酸素 / 好中球 / 慢性肉芽腫症 / GENE TRANSFECTION / ELECTROPORATION / IL-2 RECEPTOR gamma CHAIN / C-KIT / c-Kit / abl / bcr / 白血病細胞株 / 免疫磁気ビーズ / CD34 / IL-2セレプターγ鎖 / 遺伝子導入 / エレクトロポレーション / IL-2レセプターγ鎖 / c-kit / knockout mice / tyrosine kinase / T cell differntiation and growth / cytokine / IL-2 receptor / interleukin 2 (IL-2) / JAK1,3 / γ鎖 / IL-2 / γ鎖ノックアウトマウス / サイイトカイン / インターロイキン2 (IL-2) / ノックアウトマウス / チロシンキナーゼ / T細胞分化増殖 / サイトカイン / IL-2受容体 / インターロイキン2(IL-2) / SOLUBLE FACTOR / FEEDER CELL DEPENDENCY / IMMATURE MYELOYD LEUKEMIA CELL LINE / GMーCSF / 末熟骨髄性白血病細胞株 / 液性因子 / 支持細胞依存性 / 未熟骨髄性白血病細胞株 / B cell growth factor / kappa-lambda double producer / IgD producer / Epstein-Barr virus / Clonal transformation / X linked agammaglobulinemia / K-λダブルプロデュ-サ- / 未熟B細胞株 / エプスタイン-・バ-ウィルス / 無ガンマグロブリン血症 / エプスタイン・バ-ウィルス / B細胞増殖因子 / κーλ鎖2重産生株 / IgD産生細胞株 / エプスタイル・バン ウイルス / クロ-ナル・トランスフォ-メ-ション / 伴性無ガンマグロブリン血症 / ワクチン / 抗 イディオ-イディオタイプ抗体 / 抗イディオタイプ抗体 / 単クローン抗体 / 赤血球凝集素 / ロタウィルス / ケミルミネセンス / Fcレセプタ- / CD18 / CD11 / 粘着蛋白質 / 白血球 Less
  • Research Projects

    (15 results)
  • Co-Researchers

    (24 People)
  •  Development of a tumor vaccine using a membrane attached form of interleukin-15Principal Investigator

    • Principal Investigator
      MINEGISHI Masayoshi, 今野 多助
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Analysis of molecular mechanism of inherited phagocyte disorders.

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  Function of the gene of Wiskott-Aldrich syndrome

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Regulatory Factors for Growth or Apoptosis of Neuroblastoma Cells and Its Therapeutic Application

    • Principal Investigator
      MINEGISHI Masayoshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Study of mechanism of X-licombined immunodeficiency caused by mutations of the IL-2 receptor gamma chain

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Tohoku University
  •  PURIFICATION OF HEMATOPOIETIC STEM CELLS BY A CD117 MONOCLONAL ANTIBODY,MTK1, IN ORDER TO TRANSFECT HUMAN GENES-A PRELIMINARY STUDY

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      INSTITUTE FOR DEVELOPMENT,AGING AND CANCER (IDAC) Tohoku University
  •  小児白血病細胞におけるGATA転写因子郡の発現に関する研究Principal Investigator

    • Principal Investigator
      今野 多助
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  ESTABLISHMENT AND CHARACTERIZATION OF AN IMMATURE MYELOID CELL LINE, M-MOK, GROWN IN THE PRESENCE OF FIBROBLAST-FEEDER CELLS

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      RESEARCH INSTITUTE FOR TUBERCULOSIS AND CANCER, TOHOKU UNIVERSITY (RITC,TU)
  •  In vivo infusion of anti-CD11a/LFA-1 antibody for prevention and treatment of severe GVHD in HLA-nonidentical bone marrow transplantation : Its serum concentrations and biological effects.Principal Investigator

    • Principal Investigator
      KONNO Tasuke
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  CD11/CD18欠損白血球の1gGFcレセプタ-の発現異常とその病態との関連

    • Principal Investigator
      SATO Tetsuo
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Abnormal Immunoglobulin in a Patient with X-Linked Agammaglobulinemia

    • Principal Investigator
      TSUCHIYA shigeru
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  抗イデイオタイプ抗体を用いたヒトロタウィルス感染成立機序の解析

    • Principal Investigator
      佐藤 徹雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Anti-human LFA-1 monoclonal antibodies for prevention of graft failure in HLA-mismatched bone marrow transplantation.Principal Investigator

    • Principal Investigator
      KONNO Tasuke
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Etiology of congenital agammaglobulinemia: Growth defect of precursor B lymphoblastoid cell lines and immunoglobulin gene rearrangements.

    • Principal Investigator
      TSUCHIYA Shigeru
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Studies on Immunologic Reconstitution after HLA-haplotype Mismatched parental Marrow TransplantationPrincipal Investigator

    • Principal Investigator
      KONNO Tasuke
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  • 1.  MASAYOSHI Minegishi (20211592)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  TSUCHIYA shigeru (30124605)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 3.  SATO Tetsuo (90170761)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  MASAHIKO Terasawa (80192201)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  FUJIE Hiromi (60282000)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MINEGISHI Naoko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  KASAI Noriyuki (60001947)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ASAO Hironobu (80250744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  OHASHI Yoshiyuki (60250825)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KANEGASAKI Shiro (10012767)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NUNOI Hiroyuki (50218260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KOMIYAMA Jun (50020798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KITAGAWA Seiichi (50133278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SENDO Fujiro (80091833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KOBAYASHI Kunihiko (60091451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  大保 和之 (70250751)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  竹重 公一朗 (10037450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小林 陽之助 (50034062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  洲崎 健 (90134048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  土屋 滋 (90142934)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KUMAKI Satoru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  YAMAGUTI Yosiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  TERASAWA Masahiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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