SHIMAMURA Mariko 島村眞里子

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… Alternative Names

島村眞理子シマムラマリコ

島村真里子シマムラマリコ

SHIMAMURA Marko 島村眞里子

嶋村真里子シマムラマリコ

島村真理子シマムラマリコ

島村眞里子シマムラマリコ

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Researcher Number	00124462
Affiliation (based on the past Project Information) *help	2008: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2007: 東京都臨床医学総合研究所, 主任研究員 2005: THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE, RESEARCHER, 東京都臨床医学総合研究所, 主任研究員 2004: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2001 – 2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 … More 1999: TOKYO METROPOLITAN ORGANIZATION OF MEDICAL RESEARCH, TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE / DEPARTMENT OF MOLECULAR BIOLOGY / RESEARCH SCIENTIST, 東京都臨床医学総合研究所, 研究員 1999: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 1998: 財団法人東京都臨床医学総合研究所, 化学療法研究部門, 研究員 1997: (財)東京都臨床医学総合研究所, 化学療法研究部門, 研究員 1993 – 1996: 財団法人東京都臨床医学総合研究所, 化学療法研究部門, 研究員 1995: (財)東京都臨床医学総合研究所, 化学療法研究部門, 研究員 1993: THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL CANCER THERAPEUTICS, SCIENTIST, 化学療法研究部, 研究員 1992: (財)東京都臨床医学総合研究所, 化学療法研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / Applied pharmacology Except Principal Investigator 応用薬理学・医療系薬学 / Experimental pathology / 医薬分子機能学
Keywords	Principal Investigator CAM / 血管内皮細胞 / 血管新生 / 血管新生阻害 / bradykinin / 鶏卵漿尿膜 / spinorphin / endothelial cells / angiogenesis / DAS … More / KIN-841 / 酵素阻害物質 / METASTASIS / TRANSCRIPTION INHIBITOR / ENDOTHELIAL CELLS / ANGIOGENESIS INHIBITION / CYCLOOXYGENASE-2 / ANGIOGENESIS / HUMULONE / dorsal air sac / cycloxygenase2 / 腫瘍細胞 / 抗腫瘍作用 / cyclooxygenase 2 / 転移 / 転写阻害 / 鶏卵漿尿膜法 / シクロオキシゲナーゼ-2 / humulone / enzyme inhibitor / enkephalin / analgesia / ブラジキニン / 抗炎症作用 / cnkcphalin / 鎮痛作用 / angiogenic factor / inhibitor / hypoxia / 固形癌 / 阻害物質 / 血管新生因子 / 低酸素 / CAM METHOD / ANGIOGENIC INHIBITOR / ENZYME INHIBITOR / TYPE IV COLLAGENASE / CAM法 / 血管新生阻害作用 / IV型コラゲナーゼ … More Except Principal Investigator FGF / bFGF / Angiogenesis / 硫酸化多糖 / 血管内皮細胞 / 血管新生阻害 / 血管新生 / endothelial cells / chorioallantoic membrane / Herapan sulfate / Acidic polysaccharides / 低分子化 / 硫酸基 / Bfgf / Migration / Angiogenic inhibitor / Tubu formation / Marine algae / Sulfated polysaccharides / Vascular endothelial cells / 遊走 / 血管新生阻害物質 / 管腔形成 / 海藻 / 血管新生阻害作用 / インターロイン27 / IL-27 / インターロイキン27 / 抗腫瘍作用 / 免疫学 / 癌 / エポキシド基 / がん / 血管新生病 / リゾキシン / 微生物代謝産物 / Enkephalin分解酵素阻害物質 / 脊髄 / Spinorphin Less

Analysis of antitumor effect by antiangiogenic activity of interleukin-27
- Principal Investigator
  
  SHIMIZU Motomu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
HUMULONE, A POTENT COX-2 INHIBITOR FROM BEER HOP, INHIBITS ANGIOGENESISPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Mariko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE
ANGIOGENIC INHIBITION OF SPINORPHIN , A POTENT ANALGESIC AND ANTIINFLAMMATORY SUBSTANCEPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Marko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION OF MEDICAL SCIENCE
POTENT INHIBITION OF ANGIOGENESIS BY HYPOXIA-DEPENDENT NOVEL NITROIMIDAZOLEPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Mariko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION OF MEDICAL SCIENCE
A PRODUCTIVE TRIAL OF ANTI-ANGIGENIC AGENTS BASED ON A ELUCIDATION OF A MECHANISM OF bFGF AS A FIRST TRIGGER ON ANGIOGENIC PATHWAY
- Principal Investigator
  
  ASHINO Hiromi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH
微生物代謝産物リゾキシンによる血管新生阻害の機構解析とその応用
- Principal Investigator
  
  及川勉
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
A study on the regulation of angiogenesis by novel substance derived from marine algae
- Principal Investigator
  
  ASHINO Hiromi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  The Tokyo Metropolitan Institute of Medical Science
新しい疼痛制御物質・Spinorphinの作用機構の解明とその応用
- Principal Investigator
  
  HAZATO Tadahiko
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Type IV collagenase inhibitor as an angiogenic inhibitorPrincipal Investigator
- Principal Investigator
  
  SHIMAMURA Mariko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  THE TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE

All 2007 2005 2004

All Journal Article Presentation Book

[Book] がん予防食品開発の新展開・予防医学におけるバイオマーカーの評価システム2005
- Author(s)
  島村眞里子他
- Publisher
  ラクトフェリン・多機能性天然由来物質によるがん予防
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Book] がん予防食品開発の新展開 -予防医学におけるバイオマーカーの評価システム-2005
- Author(s)
  島村眞里子, 他
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] IL-27の血管新生抑制作用2007
- Author(s)
  清水本武, 島村眞里子, 善本隆之
- Journal Title
  
  臨床免疫 47
  
  Pages: 298-302
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] IL-27の血管新生抑制作用2007
- Author(s)
  清水本武, 島村眞理子, 善本隆之
- Journal Title
  
  臨床免疫 47
  
  Pages: 298-302
- Data Source
  KAKENHI-PROJECT-19590418
[Journal Article] Antitumor effect of a novel IL6/IL12 family cytokine IL-27.2005
- Author(s)
  Yoshimoto, T., Hisada, M., Shimizu, M., Shimamura, M., Mizuguchi, J.
- Journal Title
  
  Rinshomeneki 43
  
  Pages: 123-128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Two-dimensional electrophoretic analysis of disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis.2005
- Author(s)
  Shimamura, N.et al.
- Journal Title
  
  J.Electrophoresis (In press)
- NAID
  10015570338
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Levels of spinorphin in cerebrospinal fluid derived from patients with pain increase with decreasing dipeptidyl peptidase III.2005
- Author(s)
  Yamamoto, Y., Sato, H., Fukasaku, S., Hiramatsu, K., Tai, S., Shimamura M., Hazato, T.
- Journal Title
  
  Pain Research 20
  
  Pages: 27-34
- NAID
  10015444541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Levels of spinorphin in carebrospinal fluid derived from patients with pain increase with decreasing dipeptidyl peptidase III.2005
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  Pain Research 20
  
  Pages: 27-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] 新しいIL-6/IL-12ファミリーサイトカインIL-27の抗腫瘍効果2005
- Author(s)
  島村眞里子, 他
- Journal Title
  
  臨床免疫 43
  
  Pages: 123-128
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Two-dimensional electrophoretic analysis of disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis.2005
- Author(s)
  Yamamoto, Y., Akita, Y., Tai, S., Fukasaku, S., Yamaguchi, T., Oshizawa, T., Yamaoka, K., Shimamura, M., Hazato, T.
- Journal Title
  
  J.Electrophoresis 49
  
  Pages: 23-27
- NAID
  10015570338
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Levels of spinorphin in cerebrospinal fluid derived from patients with pain increase with decreasing dipeptidyl peptidase III2005
- Author(s)
  Shimamura, N.et al.
- Journal Title
  
  Pain Research (In press)
- NAID
  10015444541
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Cancer prevention and anti-metastatic effect by oral administration of bovine lactoferrin.2005
- Author(s)
  Iigo, M., Shimamura, M., Hirano, S., Nabeshima, K., Ohkubo, S., Tamura Y., Tsuda, H.
- Journal Title
  
  Carcinogenesis & Modification of Carcinogenesis
  
  Pages: 229-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] ウシラクトフェリン免疫能増強および血管新生阻害作用による発がん抑制と臨床応用.2005
- Author(s)
  島村眞里子, 他
- Journal Title
  
  Milk Science 54
  
  Pages: 273-274
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] がん予防-多機能生理活性物質ラクトフェリンからメッセージ-.2005
- Author(s)
  島村眞里子, 他
- Journal Title
  
  Milk Science 53
  
  Pages: 225-229
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Levels of spinorphin in cerebrospinal fluid derived from patients with pain increase with decreasing dipeptidyl peptidase III.2005
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  Pain Research 20
  
  Pages: 27-34
- NAID
  10015444541
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Two-dimensional electrophoretic analysis of disease-associated proteins in human cerebrospinal fluid from patients with rheumatoid arthritis.2005
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  J.Electrophoresis 49
  
  Pages: 23-27
- NAID
  10015570338
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Cancer prevention and anti-metastatic effect by oral administration of bovine lactoferrin.2005
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  Carcinogenesis and Modification of Carcinogenesis 1
  
  Pages: 229-242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Bovine lactoferrin inhibits tumor-induced angiogenesis.2004
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  Intl. J. Cancer 111
  
  Pages: 111-116
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Angiogenesis inhibitor TX-1898 : syntheses of the enantiomers of sterically diverse haloacetylcarbamoyl-2-nitroimidazole hypoxic cell radiosensitizers.2004
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  Bioorg. Med. Chem. 12
  
  Pages: 4917-4927
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Orally administered bovine lactoferrin induces caspase-1 and inter-leukin-18 in the mouse intestinal mucosa2004
- Author(s)
  Shimamura, M.et al.
- Journal Title
  
  Cytokine 25
  
  Pages: 36-44
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Design of hypoxia targeting protein tyrosine kinase inhibitor using an innovative pharmacophore 2-methylene-4-cyclopentene-1,3-dione2004
- Author(s)
  Shimamura, et al.
- Journal Title
  
  Biochim. Biophys. Acta-protein and proteomics- 1697
  
  Pages: 29-38
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Design of hypoxia targeting protein tyrosine kinase inhibitor using an innovative pharmacophore 2-methylene-4-cyclopentene-1,3-dione.2004
- Author(s)
  Hori, H., Nagasawa, H., Uto, Y., Ohkura, K., Kirk, K.L, Uehara, Y., Shimamura, M.
- Journal Title
  
  Biochim.Biophys.Acta -protein and proteomics-. 1697
  
  Pages: 29-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Orally administered bovine lactoferrin induces caspase-1 and interleukin-18 in the mouse intestinal mucosa : A possible explanation for inhibition of carcinogenesis and metastasis.2004
- Author(s)
  Iigo, M., Shimamura, M., Matsuda, E., Fujita, K., Nomoto, H., Satoh, J., Kojima, K., Moore, M., Tsuda, H.
- Journal Title
  
  Cytokine 25
  
  Pages: 36-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Orlly administered bovine lactoferrin induces caspase-1 and interleukin-18 in the mouse intestinal mucosa : A possible explanation for inhbition of carcinogenesis and metastasis.2004
- Author(s)
  Shimamura, M., et al.
- Journal Title
  
  Cytokines 25
  
  Pages: 36-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Cancer prevention by lactoferrin is accompanied by inhibition of angiogenesis.2004
- Author(s)
  Iigo, M., Shimamura, M., Nabeshima, K., Wakabayashi, H., Ohkubo, S., Tamura, Y., Tsuda, H.
- Journal Title
  
  Milk Science 53
  
  Pages: 273-274
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Design of hypoxia targeting protein tyrosine kinase inhibitor using an 2innovative pharmacophore 2-methylene-4-cyclopentene-1,3-dione2004
- Author(s)
  Shimamura, M.et al.
- Journal Title
  
  Biochim.Biophys.Acta -protein and proteomics- 1697
  
  Pages: 29-38
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Bovine lactoferrin inhibits tomor-induced angiogenesis2004
- Author(s)
  Shimamura, M.et al.
- Journal Title
  
  Intl.J.Cancer 111
  
  Pages: 111-116
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Cancer prevention -A message from multifunctional natural compounds-.2004
- Author(s)
  Tsuda, H., Ohshima, H., Fukamachi, K., Iigo, M., Takasuka, N., Matsuda, E., Sekine, K., ohkubo, S., Kohzu, T., Shimamura, M.
- Journal Title
  
  Milk Science 53
  
  Pages: 225-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Bovine lactoferrin inhibits tumor-induced angiogenesis.2004
- Author(s)
  Shimamura, M., Yamamoto, Y., Ashino, H., Oikawa, T., Hazato, T., Tsuda, H., Iigo, M.
- Journal Title
  
  Int.J.Cancer 111
  
  Pages: 111-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Angiogenesis inhibitor TX-1898: syntheses of the enantiomers of sterically diverse haloacetylcdarbamoyl-2-nitroimidazole hypoxic cell radiosensitizers2004
- Author(s)
  Shimamura, M.et al.
- Journal Title
  
  Bioorg Med Chem 12
  
  Pages: 4917-4927
- Data Source
  KAKENHI-PROJECT-16590445
[Journal Article] Angiogenesis inhibitor TX-1898 : syntheses of the enantiomers of sterically diverse haloacetylcarbamoyl-2-nitro imidazole hypoxic cell radiosensitizers.2004
- Author(s)
  Jin CZ, Nagasawa H, Shimamura M, Uto Y, Inayama S, Takeuchi Y, Kirk KL, Hori H.
- Journal Title
  
  Bioorg Med Chem. 12
  
  Pages: 4917-4927
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590445
[Presentation] L-carnosine, an endogenous bioactive dipeptide inhibits angiogenesis and tumor metastasis.2007
- Author(s)
  Shimamura, M., Ashino, H., Shimizu, M., Yamamoto, Y., Minamikawa-Tachino, R., Takahashi, S.
- Organizer
  The 66^<th> Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19590418

1. ASHINO Hiromi (40222608)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. HAZATO Tadahiko (60109949)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SHIMIZU Motomu (10124463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. YOSHIMOTO Takayuki (80202406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. AOYAGI Takaaki (10159303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HORI Hitoshi (90119008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TOBE Hiroyasu (30300643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 茅稽二 (20124969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 及川勉 (40120141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岩崎成夫 (00013326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIMAMURA Mariko 島村 眞里子

島村 眞理子 シマムラ マリコ

島村 真里子 シマムラ マリコ

SHIMAMURA Marko 島村 眞里子

嶋村 真里子 シマムラ マリコ

島村 真理子 シマムラ マリコ

島村 眞里子 シマムラ マリコ

Research Projects

Research Products

Co-Researchers

Analysis of antitumor effect by antiangiogenic activity of interleukin-27

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HUMULONE, A POTENT COX-2 INHIBITOR FROM BEER HOP, INHIBITS ANGIOGENESISPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ANGIOGENIC INHIBITION OF SPINORPHIN , A POTENT ANALGESIC AND ANTIINFLAMMATORY SUBSTANCEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

POTENT INHIBITION OF ANGIOGENESIS BY HYPOXIA-DEPENDENT NOVEL NITROIMIDAZOLEPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A PRODUCTIVE TRIAL OF ANTI-ANGIGENIC AGENTS BASED ON A ELUCIDATION OF A MECHANISM OF bFGF AS A FIRST TRIGGER ON ANGIOGENIC PATHWAY

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

微生物代謝産物リゾキシンによる血管新生阻害の機構解析とその応用

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on the regulation of angiogenesis by novel substance derived from marine algae

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新しい疼痛制御物質・Spinorphinの作用機構の解明とその応用

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Type IV collagenase inhibitor as an angiogenic inhibitorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] がん予防食品開発の新展開・予防医学におけるバイオマーカーの評価システム2005

Author(s)

Publisher

Description

Data Source

[Book] がん予防食品開発の新展開 -予防医学におけるバイオマーカーの評価システム-2005

Author(s)

Publisher

Data Source

[Journal Article] IL-27の血管新生抑制作用2007

Author(s)

Journal Title

Data Source

[Journal Article] IL-27の血管新生抑制作用2007

Author(s)

Journal Title

Data Source

SHIMAMURA Mariko 島村眞里子

島村眞理子シマムラマリコ

島村真里子シマムラマリコ

SHIMAMURA Marko 島村眞里子

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