Matsuzaki Katsumi 松崎勝巳

… Alternative Names

MATSUZAKI Katsumi 松崎勝巳

松崎勝己マツザキカツミ

松崎勝巳マツザキカツミ

松ざき勝巳マツザキカツミ

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Researcher Number	00201773
Other IDs
Affiliation (Current)	2025: 京都大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 京都大学, 薬学研究科, 教授 2012 – 2015: 京都大学, 薬学研究科(研究院), 教授 2008 – 2012: 京都大学, 薬学研究科, 教授 2011: 京都大学, 大学院・薬学研究科, 教授 2003 – 2006: 京都大学, 薬学研究科, 教授 … More 2000 – 2002: 京都大学, 生命科学研究科, 助教授 2001: 京都大学, 生命科学, 助教授 2000 – 2001: 京都大学, 大学院・生命科学研究科, 助教授 1998: 京都大学, 薬学研究科, 助教授 1997: 京都大学, 大学院・薬学研究科, 助教授 1996: 京都大学, 薬学部, 助手 1990 – 1991: 京都大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Biological Sciences / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy / Pharmaceutical Sciences and related fields / 医薬分子機能学 / Living organism molecular science / Science and Engineering Except Principal Investigator Biological Sciences / Physical pharmacy / Physical pharmacy
Keywords	Principal Investigator 膜タンパク質 / 可溶化剤 / アルツハイマー病 / 抗菌性ペプチド / 蛍光イメージング / 細胞毒性 / ガングリオシド / 脂質ラフト / アミロイドβ蛋白 / マガイニン2 … More / マガイニン / 高分解能NMR / オリゴマー化 / GPCR / β-シート / 膜透過性 / 超分子 / 相乗効果 / PGLa / 膜透過 / ペプチド / 膜タンパク質可溶化 / アミロイドβ / ＮＭＲ / CELL PENETRATING PEPTIDE / AMPHIPATHIC HELIX / MAGAININ 2 / PEPTIDE-LIPID SUPRAMOLECULAR COMPLEX PORE / ELECTROSTATIC REPULSION / TRANSLOCATION / BUFORIN 2 / ANTIMICROBIAL PEPTIDE / ドラックデリバリー / 細胞内移行 / ベクター / 薬物キャリアー / 細胞膜透過 / 曲率 / 濃度依存性 / シス-トランス互変異性 / プロリン / 細胞透過ペプチド / 両親媒性ヘリックス / ペプチド-脂質超分子複合体ポア / 静電反発 / ブフォリン2 / 無細胞合成 / 脂質ナノディスク / 蛋白質 / 膜蛋白質 / イメージング / クロスリンク / グルタミン酸受容体 / β2アドレナリン受容体 / コンフォメーション変化 / 蛍光励起エネルギー移動 / βアドレナリン受容体 / タキプレシンI / ポリエチレングリコール / リポ多糖 / エンドトキシンショック / 膜透過ペプチド / アルキル化 / 細胞内ループ / 線維構造 / 凝集阻害 / コレステロール / 凝集体 / シャペロン / アミロイド線維 / 脂質膜 / α-ヘリックス / 分子認識 / 生体防御ペプチド / 溶血性 / 膜 / 静電的相互作用 / グラム陰性菌 / 抗菌剤 / フリッププロップ / マストパラン / 超分子複合体 / 脂質 … More Except Principal Investigator 一分子蛍光エネルギー移動 / モデル膜貫通ヘリックス / 一分子計測 / 膜貫通ヘリックス / 一分子FRET / モデル膜貫通へリックス / 膜タンパク質フォールディング / hereditary variant / microdomain / synapse / apolipoprotein F. / ganglioside / amyloid β-protein / Alzheimer's disease / コレステロール / GM1ガングリオシド / 老人斑 / アミロイドβ蛋白 / 遺伝的変異型 / 遺伝子変異型 / マイクロドメイン / シナプス / アポリポ蛋白E / ガングリオシド / アミロイド蛋白 / アルツハイマー病 / Orientation / Conformation / Membrane permeability / Lipid membrane / Tachyplesin / Magainin / Trichopolyn / Hypelcin / タチプレシン / 配向 / コンホメ-ション / 膜透過性 / 脂質膜 / タキプレシン / マガイニン / トリコポリン / ヒペルシン / リン酸化 / プロテインキナーゼ / COS細胞 / galactosylsphingosine / Globoid cells / krabbe病 / ISP-1 / 酵母 / 多核細胞 / glactosylsphimgosine / Globoid cell / Krabbe病 / アセチル化 / 初期エンドソーム / リソソーム / Rom2 / PI4,5P2 / MSS4 / スフィンゴ脂質 / 細胞質分裂 / 細胞内小器官 / 多核 / サイコシン Less

新規リン脂質誘導体可溶化剤を用いた革新的膜タンパク質研究プラットホームの構築Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
In-cell分光法によるアミロイドβ産生制御機構・構造変化の解明と創薬Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
High resolution NMR structure determination of membrane proteins using novel phospholipid analogsPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Development of a small-sized labeling method for membrane proteins and its application for heterooligomer analysisPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
Novel Phospholipid Analogs for NMR Structural Determination of Membrane ProteinsPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pharmaceutical Sciences and related fields
- Research Institution
  Kyoto University
Development of a novel fluorescent labeling method for detecting heterooligomers of membrane proteins on living cellsPrincipal Investigator
- Principal Investigator
  
  Katsumi Matsuzaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of phospholipid analogs for stable solubilization of membrane proteins and application for high resolution NMR analysisPrincipal Investigator
- Principal Investigator
  
  Matsuzaki Katsumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Association dynamics of transemrbane helices detected by single-molecle FRET
- Principal Investigator
  
  Yano Yoshiaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Application of novel labeling method for membrane proteins to aggregational analysis and its sophisticationPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Katsumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Development of novel nano discs for structural analysis of membrane proteinsPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Katsumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Visualization and analysis of receptor oligomerization in living cells by using novel fluorescence labeling methodPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Katsumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
抗菌性ペプチドをベースとした世界初のエンドトキシンショック治療薬の開発Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
GM1結合型アミロイドβ蛋白の構造解析Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
膜透過型細胞内ループを用いたGPCRのGタンパク質活性化機構解明Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
アミロイドβ蛋白の凝集開始初期過程の高感度解析Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
脂質ラフトにおける膜活性型アミロイドβ蛋白の形成と防御Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ラフト様脂質環境におけるアミロイドβ蛋白の凝集機構の解明と凝集体の特性解析Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
ELUCIDATION OF THE MECHANISM OF EFFECTIVE MEMBRANE PERMEATION OF BUFORIN 2 AND ITS APPLICATION TO VECTOR FOR INTRACELLULAR DRUG DELIVERYPrincipal Investigator
- Principal Investigator
  
  MATSUZAKI Katsumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
膜環境下で形成される異種生体防御ペプチド間の希少高活性超分子Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
細胞質分裂に関与するスフィンゴ脂質シグナリング
- Principal Investigator
  
  小堤保則
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
An investigation into molecular mechanism underlying Aβ assembly
- Principal Investigator
  
  YANAGISAWA Katsuhiko
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Longevity Sciences
脂質膜中での生体防御ペプチド間のヘテロ分子認識に基づく高活性超分子形成Principal Investigator
- Principal Investigator
  
  松崎勝巳 (松ざき勝巳)
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
ペプチド-脂質超分子複合体ポアによるペプチド・イオン・脂質の共役膜輸送Principal Investigator
- Principal Investigator
  
  松崎勝己
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
生体防御ペプチドをリ-ドとした選択毒性の高い抗菌性ペプチドの創製Principal Investigator
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Interactions of antibiotic peptides with lipid membranes
- Principal Investigator
  
  MIYAJIMA Koichiro
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University

[Book] ナノバイオ技術と最新創薬応用研究「新規蛍光標識法を用いた創薬ターゲット膜受容体のイメージング解析」2012
- Author(s)
  松崎勝巳、矢野義明、他58名
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21390007
[Book] ナノバイオ技術と最新創薬応用研究「新規蛍光標識法を用いた創薬ターゲット膜受容体のイメージング解析」2012
- Author(s)
  松崎勝巳、矢野義明, ほか
- Total Pages
  288
- Publisher
  メディカルドゥ
- Data Source
  KAKENHI-PROJECT-21390007
[Book] 薬学分析化学の最前線2009
- Author(s)
  松崎勝巳、矢野義明、他120名
- Publisher
  じほう
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Live-cell imaging of membrane proteins by a coiled-coil labeling method: Principles and applications2019
- Author(s)
  Yoshiaki Yano and Katsumi Matsuzaki
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1862 Issue: 5 Pages: 1011-1017
- DOI
  10.1016/j.bbamem.2019.02.009
- NAID
  120006591375
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02561
[Journal Article] Oligomerization-function relationship of EGFR on living cells detected by the coiled-coil labeling and FRET microscopy2015
- Author(s)
  Yamashita H., Yano Y., Kawano K., Matsuzaki K.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1848 Issue: 6 Pages: 1359-1366
- DOI
  10.1016/j.bbamem.2015.03.004
- NAID
  120005621952
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390009
[Journal Article] Cholesterol-induced lipophobic interaction between transmembrane helices using ensemble and single-molecule fluorescence resonance energy transfer2015
- Author(s)
  Yano Y, Kondo K, Kitani R, Yamamoto A, Matsuzaki K
- Journal Title
  
  Biochemistry
  
  Volume: 54 Issue: 6 Pages: 1371-1379
- DOI
  10.1021/bi501528e
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460034
[Journal Article] A dimer is the minimal proton-conducting unit of the influenza a virus M2 channel2014
- Author(s)
  Kawano K., Yano Y., Matsuzaki K.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 426 Issue: 14 Pages: 2679-2691
- DOI
  10.1016/j.jmb.2014.05.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390009
[Journal Article] Stoichiometric analysis of oligomerization of membrane proteins on living cells using coiled-coil labeling and spectral imaging2013
- Author(s)
  Kawano K, Omae K, Matsuzaki S, Matsuzaki K
- Journal Title
  
  Anal. Chem.
  
  Volume: 85 Issue: 6 Pages: 3454-3461
- DOI
  10.1021/ac400177a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390009
[Journal Article] Coiled-coil tag-probe labeling method for live-cell imaging of membrane receptors2012
- Author(s)
  Yoshiaki Yano, Kenichi Kawano, Kaoru Omae, and Katsumi Matsuzaki
- Journal Title
  
  Methods Enzymol
  
  Volume: 504 Pages: 355-370
- DOI
  10.1016/b978-0-12-391857-4.00018-5
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] 新規蛍光ラベル法による膜受容体の内在化の可視化2010
- Author(s)
  松崎勝巳, 矢野義明
- Journal Title
  
  生化学
  
  Volume: 82 Pages: 494-497
- NAID
  10026899941
- URL
  http://www.jbsoc.or.jp/event/magazine/index.html
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Design of a soluble transmembrane helix for measurements of water-membrane partitioning2010
- Author(s)
  Yoshiaki Yano, Norie Shimai, Katsumi Matsuzaki
- Journal Title
  
  J.Phys.Chem.B. 114
  
  Pages: 1925-1931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Control of cell selectivity of antimicrobial peptides2009
- Author(s)
  K.Matsuzaki
- Journal Title
  
  Biochim.Biophys.Acta 1788
  
  Pages: 1687-1692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659005
[Journal Article] Tag-probe fluorescent labeling methods for live-cell imaging of membrane proteins2009
- Author(s)
  Yoshiaki Yano, Katsumi Matsuzaki
- Journal Title
  
  Biochim.Biophys.Acta 1788
  
  Pages: 2124-2131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Ganglioside-induced formation of amyloid fibrils by hIAPP in lipid rafts2009
- Author(s)
  Masaki Wakabayashi, Katsumi Matsuzaki
- Journal Title
  
  FEBS Lett. 583
  
  Pages: 2854-2858
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article]2009
- Author(s)
  松崎勝巳, 矢野義明
- Journal Title
  
  薬学分析化学の最前線(じほう)
  
  Pages: 170-171
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Tag-probe fluorescent labeling methods for live-cell imaging of membrane proteins Biochim2009
- Author(s)
  Yoshiaki Yano and Katsumi Matsuzaki
- Journal Title
  
  Biophys. Acta
  
  Volume: 1788 Issue: 10 Pages: 2124-2131
- DOI
  10.1016/j.bbamem.2009.07.017
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Peptide-lipid huge toroidal pore : a new antimicrobial mechanism mediated by a lactococcal bacteriocin, lacticin Q2009
- Author(s)
  Fuminori Yoneyama, Yuichi Imura, Kanako Ohno, Takeshi Zendo, Jiro Nakayama, Katsumi Matsuzaki, Kenji Sonomoto
- Journal Title
  
  Antimicrob.Agents Chemother 53
  
  Pages: 3211-3217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390007
[Journal Article] Magainin 2 in Action : Distinct Modes of Membrane Permeabilization in Living Bacterial and Mammalian Cell2008
- Author(s)
  Y. Imura, N. Choda & K. Matsuzaki
- Journal Title
  
  Biophys. J.
  
  Volume: 95 Pages: 5757-5765
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659005
[Journal Article] Action mechanism of tachyplesin I and effects of PEGylation2007
- Author(s)
  Y.Imura, M.Nishida, Y.Ogawa, Y.Takakura, K.Matsuzaki
- Journal Title
  
  Biochim.Biophys.Acta 1768
  
  Pages: 1160-1169
- Data Source
  KAKENHI-PROJECT-17651125
[Journal Article] Cross-seeding of wild-type and hereditary variant-type amyloid beta-proteins in the presence of gangliosides2005
- Author(s)
  N.Yamamoto, K.Matsuzaki, K.Yanagisawa
- Journal Title
  
  J.Neurochem. 95・4
  
  Pages: 1167-1176
- Data Source
  KAKENHI-PROJECT-17025022
[Journal Article] Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein, an endogenous seed for Alzheimer amyloid.2001
- Author(s)
  Kakio A, (Yanagisawa K, Matsuzaki K) et al.
- Journal Title
  
  J Biol Chem 276
  
  Pages: 24985-24990
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Journal Article] Cholesterol-dependent formation of GM1 ganglioside-bound amyloid β-protein an endogenous seed for Alzheimer amyloid.2001
- Author(s)
  Kakio A, (Yanagisawa K, Matsuzaki K) et al.
- Journal Title
  
  J Biol Chem 276
  
  Pages: 24985-24990
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12210022
[Patent] 新規なステロイド化合物2020
- Inventor(s)
  松崎　勝巳、矢野　義明、高木　麻衣、山岡　庸介、高須　清誠
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-039999
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K22493
[Presentation] リン脂質誘導体カクテルによる膜タンパク質の小サイズでの安定な可溶化2024
- Author(s)
  松崎勝巳; 高木麻衣; 秦綾美; 長谷綾菜; 横山あずさ; 林田幸一; 星遥華; 山崎大資; 大山侃志; 河野健一; 黒田悠介; 山岡庸介; 星野大; 矢野義明; 高須清誠日本薬学会第144年会
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18184
[Presentation] 新規リン脂質誘導体による可溶化GPCRのリガンド結合能評価2024
- Author(s)
  星遥華; 河野健一; 藤原敬宏; 黒田悠介; 山岡庸介; 高須清誠; 松崎勝巳
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K18184
[Presentation] 神経細胞膜を介したアミロイドβタンパク質の凝集・毒性発現機構2024
- Author(s)
  松崎勝巳
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K21355
[Presentation] 神経細胞膜上における Aβ40 と 42 共存下での線維形成機構2023
- Author(s)
  川口真由; 河野健一; 松崎勝巳
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21355
[Presentation] GPCRのヘテロ会合体検出のための新規コイルドコイル型ラベルペアの開発2021
- Author(s)
  高野淳、矢野義明、松崎勝巳
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-18H02561
[Presentation] 生細胞膜中で形成されるアミロイドβタンパク質の構造解析2021
- Author(s)
  角友登、河野健一、矢野義明、星野大、松崎勝巳
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21355
[Presentation] アスパラギン間相互作用に基づく新規コイルドコイルラベル法の開発2019
- Author(s)
  高野淳、矢野義明、松崎勝巳
- Organizer
  第17 回次世代を担う若手のためのフィジカルファーマフォーラム
- Data Source
  KAKENHI-PROJECT-18H02561
[Presentation] Development of a novel coiled-coil labeling method for heterooligomer detection2019
- Author(s)
  Jun Takano, Yoshiaki Yano, Katsumi Matsuzaki
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-18H02561
[Presentation] 二回膜貫通へリックス間相互作用の一分子蛍光測定に用いるモデルペプチドの合成2016
- Author(s)
  渡邊由宇太、近藤小太郎、矢野義明、松崎勝巳
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-25460034
[Presentation] 新規小分子ラベル法とin-cell FRETを用いた膜タンパク質の会合状態の定量的解析2014
- Author(s)
  河野健一、矢野義明、大前薫、松崎紗矢香、松崎勝巳
- Organizer
  第64回日本薬学会近畿支部大会
- Place of Presentation
  京都薬科大学（京都府）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] Dimer is a Minimal Functional Unit for Influenza A Virus M2 Channel on Biomembrane2014
- Author(s)
  Kenich Kawano, Yoshiaki Yano and Katsumi Matsuzaki
- Organizer
  Biophysical society 58th Annual meeting
- Place of Presentation
  Moscone Center, San Francisco, CA（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] 抗インフルエンザウイルス薬アマンタジン耐性M2 S31N変異株の生体膜中における会合状態2014
- Author(s)
  河野健一、矢野義明、松崎勝巳
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館（熊本県）
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] 膜タンパク質変成作用の少ない可溶化剤の開発2013
- Author(s)
  林田幸一、茂木雄三、山岡庸介、高須清誠、矢野義明、松崎勝巳
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-24659016
[Presentation] Dimer is a minimal functional unit for influenza A virus M2 channel on biomembrane2013
- Author(s)
  Kenich Kawano, Yoshiaki Yano and Katsumi Matsuzaki
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府）
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] コイルドコイル蛍光ラベル法を用いた生細胞での上皮成長因子受容体多量体形成の検出2013
- Author(s)
  山下博隆、河野健一、矢野義明、松崎勝巳
- Organizer
  第35回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学大学院薬学研究科（東京都）
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] 生細胞膜タンパク質の会合・内在化の可視化解析ツール : コイルドコイルラベル法2013
- Author(s)
  矢野義明、河野健一、大前薫、竹田有希、松崎紗矢香、松崎勝巳
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] コイルドコイル蛍光ラベル法を用いた生細胞での上皮成長因子受容体多量体形成の検出2013
- Author(s)
  山下博隆、河野健一、矢野義明、松崎勝巳
- Organizer
  第11回次世代を担う若手のためのフィジカル・ファーマフォーラム(PPF)2013
- Place of Presentation
  清水テルサ（静岡県）
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] Single-molecule detection of association-dissociation dynamics of transmembrane helices induced by cholesterol2013
- Author(s)
  Yoshiaki Yano, Kotaro Kondo, Ryota Kitani and Katsumim Matsuzaki
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク（大阪府）
- Data Source
  KAKENHI-PROJECT-25460034
[Presentation] 膜タンパク質変性作用の少ない可溶化剤の開発2013
- Author(s)
  林田幸一、茂木雄三、山岡庸介、高須清誠、矢野義明、松崎勝巳
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-24659016
[Presentation] Stoichiometric analysis of oligomerization of membrane proteins on living cell surface2012
- Author(s)
  Kawano K, Omae K, Matsuzaki S, Yano Y, Matsuzaki K
- Organizer
  The 7th Seoul-Kyoto-Osaka joint symposium on pharmaceutical sciences for young scientists
- Place of Presentation
  京都大学薬学部(京都府)
- Year and Date
  2012-05-23
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] Detection of oligomerization and internalization of membrane receptors in living cells by novel coiled-coil fluorescence labeling method2011
- Author(s)
  Yano Y, Kawano K, Omae K, Matsuzaki K
- Organizer
  AIMECS11
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] Internalization and oligomerization of membrane receptors in living cells as detected by novel coiled-coil fluorescence labeling methods2011
- Author(s)
  Katsumi Matsuzaki, Kaoru Omae, Yoshiaki Yano
- Organizer
  International Peptide Symposium
- Place of Presentation
  Kyoto International Conference Center(京都府)
- Year and Date
  2011-12-06
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] Behaviors of receptors as analyzed by novel fluorescence labeling method for membrane proteins2011
- Author(s)
  松崎勝巳
- Organizer
  第49回日本生物物理学会シンポジウム
- Place of Presentation
  兵庫県立大学(兵庫県)(招待講演)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] Family A GPCRの受容体活性に会合体形成は本当に必要か2011
- Author(s)
  河野健一、大前薫、矢野義明、松崎勝巳
- Organizer
  第9回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  ホテル箱根アカデミー(神奈川県)
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] Behaviors of receptors as analyzed by novel fluorescence labeling method for membrane proteins2011
- Author(s)
  松崎勝巳
- Organizer
  第49回日本生物物理学会シンポジウム
- Place of Presentation
  兵庫県立大学(兵庫県)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] 新規蛍光標識法による膜受容体の可視化解析とリガンドスクリーニング2010
- Author(s)
  松崎勝巳
- Organizer
  第28回物性物理化学研究会
- Place of Presentation
  京都大学(京都府)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] 新規小分子蛍光ラベル法による生細胞でのGPCRオリゴマーの検出2010
- Author(s)
  大前薫, 矢野義明, 松崎勝巳
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] Oligomerization of membrane receptors2010
- Author(s)
  Yoshiaki Yano, Kaoru Omae, and Katsumi Matsuzaki
- Organizer
  FRET analysis using coiled-coil tag-probe labeling and spectral imaging Biophysical Society 54th annual meeting Aan Francisco
- Place of Presentation
  USA
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] Internalization and oligomerization of membrane receptors in living cells as detected by novel coiled-coil fluorescence labeling methods2010
- Author(s)
  Katsumi Matsuzaki, Kaoru Omae, Yoshiaki Yano
- Organizer
  5^<th> International Peptide Symposium
- Place of Presentation
  Kyoto International Conference Center(京都府)
- Year and Date
  2010-12-06
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] コイルドコイル蛍光ラベル法:次世代の膜受容体可視化ツール2010
- Author(s)
  矢野義明、大前薫、竹田有希、松崎勝巳
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山国際会議場(富山県)
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] 新規小分子蛍光ラベル法による生細胞でのGPCRオリゴマーの検出2010
- Author(s)
  大前薫、矢野義明、松崎勝巳
- Organizer
  日本薬学会第130年会岡山大学
- Place of Presentation
  岡山県
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] OLIGOMERIZATION OF MEMBRANE RECEPTORS : FRET ANAL YSIS USING COILED-COIL TAG-PROBE LABELING AND SPECTRAL IMAGING2010
- Author(s)
  Yoshiaki Yano, Kaoru Omae, Katsumi Matsuzaki
- Organizer
  Biophysical Society 54th Annual Meeting
- Place of Presentation
  San Francisco (Moscone Cantor), USA
- Year and Date
  2010-02-21
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] プロリンの導入及び塩基性アミノ酸が抗菌性ペプチドの作用標的に及ぼす影響2009
- Author(s)
  長田尚樹、井村雄一、松崎勝巳
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20659005
[Presentation] Detection of internalization and oligomerization of membrane receptors using coiled-coil fluorescence labeling method2009
- Author(s)
  Yoshiaki Yano, Kaoru Omae, and Katsumi Matsuzaki
- Organizer
  第46回ペプチド討論会
- Place of Presentation
  北九州国際会議場(福岡県)
- Year and Date
  2009-11-04
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] 受容体内在化を検出する簡便なリガンドスクリーニング法の開発2009
- Author(s)
  矢野義明, 松崎勝巳
- Organizer
  日本ケミカルバイオロジー学会第4回年会
- Place of Presentation
  神戸
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-21390007
[Presentation] プロリンの導入及び荷電数の増加による抗菌性ペプチドの作用標的の制御2008
- Author(s)
  長田尚樹、井村雄一、松崎勝巳
- Organizer
  第45回ベプチド討論会
- Place of Presentation
  東京
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20659005
[Presentation] Single-molecule FRET detection of GXXXG-mediated transmembrane helical interactions
- Author(s)
  Yoshiaki Yano, Kotaro Kondo, and Katsumi Matsuzaki
- Organizer
  Biophysical society 59th annual meeting
- Place of Presentation
  Baltimore, ML, USA
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-25460034
[Presentation] 一分子FRET測定法を用いた，膜貫通ヘリックス間相互作用へのGXXXGモチーフの寄与の解明
- Author(s)
  近藤小太郎、矢野義明、松崎勝巳
- Organizer
  第５２回日本生物物理学会
- Place of Presentation
  札幌コンベンションセンター（北海道）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460034
[Presentation] 一分子蛍光測定法を用いた，膜貫通ヘリックス間相互作用へのGXXXGモチーフの寄与の解析
- Author(s)
  近藤小太郎、矢野義明、松崎勝巳
- Organizer
  第１２回次世代を担う若手のためのフィジカル・ファーマフォーラム
- Place of Presentation
  箱根高原ホテル（神奈川県）
- Year and Date
  2014-07-14 – 2014-07-15
- Data Source
  KAKENHI-PROJECT-25460034
[Presentation] コイルドコイル標識法とin-cell蛍光測定法による生細胞膜上での膜タンパク質の会合計測
- Author(s)
  松崎勝巳
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫県）
- Year and Date
  2015-03-26 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] 生細胞におけるアミロイド前駆体タンパク質の会合状態解
- Author(s)
  上山和輝、矢野義明、松崎勝巳
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390009
[Presentation] 共有結合型コイルドコイルラベル法の確立とグリコフォリンAの会合状態の解明
- Author(s)
  古川奈美、矢野義明、小野智史、松崎勝巳
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸サンボーホール（兵庫県）
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24390009

1. YANO Yoshiaki (60402799)

# of Collaborated Projects: 8 results

# of Collaborated Products: 44 results
2. HOSHINO Masaru (70304053)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
3. 河野健一 (70732874)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. HANDA Teturou (00025719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MIYAJIMA Koichiro (30025689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUJII Nobutaka (60109014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YANAGISAWA Katsuhiko (10230260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 小堤保則 (70205425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 竹松弘 (80324680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岡昌吾 (60233300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山銅ゆかり (70359785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 若松馨 (40222426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 星野忠次 (90257220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Matsuzaki Katsumi 松崎 勝巳

MATSUZAKI Katsumi 松崎 勝巳

松崎 勝己 マツザキ カツミ

松崎 勝巳 マツザキ カツミ

松ざき 勝巳 マツザキ カツミ

Research Projects

Research Products

Co-Researchers

新規リン脂質誘導体可溶化剤を用いた革新的膜タンパク質研究プラットホームの構築Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

In-cell分光法によるアミロイドβ産生制御機構・構造変化の解明と創薬Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

High resolution NMR structure determination of membrane proteins using novel phospholipid analogsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a small-sized labeling method for membrane proteins and its application for heterooligomer analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel Phospholipid Analogs for NMR Structural Determination of Membrane ProteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of a novel fluorescent labeling method for detecting heterooligomers of membrane proteins on living cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of phospholipid analogs for stable solubilization of membrane proteins and application for high resolution NMR analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association dynamics of transemrbane helices detected by single-molecle FRET

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of novel labeling method for membrane proteins to aggregational analysis and its sophisticationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel nano discs for structural analysis of membrane proteinsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Visualization and analysis of receptor oligomerization in living cells by using novel fluorescence labeling methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

抗菌性ペプチドをベースとした世界初のエンドトキシンショック治療薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Matsuzaki Katsumi 松崎勝巳

MATSUZAKI Katsumi 松崎勝巳

松崎勝己マツザキカツミ

松崎勝巳マツザキカツミ

松ざき勝巳マツザキカツミ