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Haginoya Kazuhiro  萩野谷 和裕

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… Alternative Names

HAGINOYA Kazuhiro  萩野谷 和裕

萩野 和裕  ハギノ カズヒロ

萩野谷 和裕  ハギノヤ カズヒロ

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Researcher Number 00208414
Other IDs
Affiliation (based on the past Project Information) *help 2016 – 2019: 東北大学, 医学系研究科, 非常勤講師
2002 – 2004: Department of Pediatrics, Associate Professor, 大学院・医学系研究科, 助教授
2000 – 2003: Tohoku University, Department of Pediatrics Lecturer, 大学院・医学系研究科, 講師
1997 – 1999: 東北大学, 医学部・附属病院, 講師
1998: 東北大学, 医学部附属病院, 講師 … More
1995: 東北大学, 医学部, 助手
1993: 東北大学, 医学部・附属病院, 助手
1988: 東北大学, 医 学部附属病院, 助手
1988: 東北大学, 医学部付属病院, 助手
1988: Tohoku Univ. Hospital, Department of Pediatrics, Instructor, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Pediatrics / Pediatrics
Except Principal Investigator
Pediatrics / Radiation science
Keywords
Principal Investigator
MELAS / てんかん / 小頭症 / 臨床 / 脳神経疾患 / 遺伝学 / 遺伝性痙性対麻痺 / てんかん性脳症 / 痙性対麻痺 / 全エキソーム解析 … More / MRI / 満期産 / 遺伝子 / 脳性麻痺 / anti-cardiolipin antibody / West syndrome / Eplepsy / 免疫細織化学 / western blottin / 抗カルジオリピン杭体 / 点頭てんかん / 抗カルジオリピン抗体 / A3243G / heteroplasmy / mitochondrial DNA / mitochondrial disease / 低酸素 / 高酸素 / 培養線維芽細胞 / 変異率 / ヘテロプラスミー / A3243G変異 / ヘテルプラスミー / ミトコンドリアDNA / ミトコンドリア病 / 免疫組織化学 / 接着因子 / パッチクランプ法 / 大脳皮質形成異常 / スライスパッチクランプ / 大脳皮質形成障害 / カイニン酸 / 電撃痙攣 / ジストロフィン … More
Except Principal Investigator
P300 / SEF / MEG / ヒスタミンH3受容体 / cytochrome c oxidase deficiency / mitochondrial DNA / 培養線維芽細胞 / ミトコンドリアDNA / immunoblotting / NADH-ubiquinone oxidoreductase deficiency / mitochondrial myopathy / 組織特異性 / Digitonin 処理 / 免疫組織化学 / NADH-coQ reductase欠損症 / cytochrome C oxidase 欠損症 / ミトコンドリアサイトパチー / ミトコンドリア電子伝達系酸素欠損症 / 細胞毎のモザイク / CCO活性電顕 / 免疫ブロット / 複合体I欠損症 / 複合体IV欠損症 / ミトコンドリア電子伝達酵素欠損症 / Stimulation of Japanese words / 語音識別 / 聴覚誘発の【P_(300)】 / 音声刺激 / 単語認識反応速度 / 日本語音声刺激 / MRI-ASL perfusion imaging / brain tumor / moyamoya disease / FAIR(Fluid attenuated inversion recovery)法 / 非侵襲的脳血流画像 / MRI-ASL法 / MRI-ASL法灌流画像 / 脳腫瘍 / モヤモヤ病 / patch clamp / antihistaminic agents / temperature change / abnormal channel / voltage-gated / potassium channel / sodium channel / Febrile seizure / チャネル以上 / K^+チャネル / Na^+チャネル / NA+チャネル / 抗ヒスタミン薬 / 温度変化 / パッチクランプ / チャネル異常 / 電位依存性 / K+チャネル / Na+チャネル / 熱性けいれん / waking reaction / histamine H3 receptor antagonist / intrinsic histamine / convulsion / histamine H3 receptor / histamine H1 receptor / central histamine / thioperamide / ペンチレンテトラゾール / キンドリング / 覚醒反応 / H3受容体阻害薬 / 内因性ヒスタミン / けいれん / ヒスタミンH1受容体 / 中枢ヒスタミン / detection of epileptic activity / cortical dysplasia / neuronal plasticity / bandheterotopia / 大脳半球巨大嚢胞 / てんかん波検出 / 皮質形成異常 / 脳の代償機能 / H3-receptor / methylhistamine / PTZ kindling / H1受容体ノックアウトマウス / メチルヒスタミン / PTZキンドリング / SURF1 genes / pyruvate dehydrogenase deficiency / ATPase 6 / Leigh's disease / 高酸素 / 低酸素 / 変異率 / ミトコンドリア病 / ピルビン酸脱水素欠損症 / SURF1 / チトクロームオキシダーゼ欠損症 / ピルビン酸脱水素酵素欠損症 / ATPase6 / Leigh脳症 / theophylline induced seizures / PTZ kindling model / electroshock model / age dependent epilepsy / テオフィリン / 幼弱動物実験 / 易けいれん性 / 難治てんかん / テオフィリン誘発けいれん / ペンチレンテトラゾールキンドリングモデル / 電撃けいれん / 年齢依存性てんかん / 電顕細胞化学 / ミトコンドリア / チトクロームC酸化酵素欠損症 / アデノウィルスベクター / 遺伝子治療 / フェニルケトン尿症 Less
  • Research Projects

    (17 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (20 People)
  •  Genetic background of unexplained full-term cerebral palsyPrincipal Investigator

    • Principal Investigator
      Haginoya Kazuhiro
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Neurophysiological and molecular approach for evaluating mechanism of pathogenesis of febrile seizure

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Anticardolipin antibody and childhood epiepsyPrincipal Investigator

    • Principal Investigator
      HAGINOYA Kazuhiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  MRI-ASL perfusion imaging -evaluation in pediatric brain and moyamoya disease-

    • Principal Investigator
      TAKAHASHI Shoki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Research for development of new antiepileptic drug with wake-promoting effect

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Therapeutic research for mitochondrial diseasePrincipal Investigator

    • Principal Investigator
      HAGINOYA Kazuhiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  ヒト大脳皮質異形成のてんかん源性獲得に関する組織学的、生理学的研究Principal Investigator

    • Principal Investigator
      萩野谷 和裕
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Development of a new antiepileptic agent without hypnotic effects

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Study of neuronal plasticity in children by biomagnetism

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  摘出組織を用いた大脳皮質形成障害のてんかん源性の解明Principal Investigator

    • Principal Investigator
      萩野 和裕
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Study on pathogenesis of Leigh's encephalomyelopathy

    • Principal Investigator
      MIYABAYASHI S
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Neurophamacological basic research for intractable epilepsy in childhood

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  フェニルケトン尿症モデルマウスにおける遺伝子治療の基礎的研究

    • Principal Investigator
      松原 洋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  ジストロフィンの脳内生理機能の解明Principal Investigator

    • Principal Investigator
      萩野谷 和裕
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  電顕組織科学の形態計測的手法によるチトクロームCオキシターゼ欠損の多 様性の解明

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Analysis of protein of electron-transfer enzymes in mitochondrial cytopathy

    • Principal Investigator
      MIYABAYASHI Shigeaki
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Development of a Stimulator for Elicitation of Auditory Evoked Potentials by Japanese Words.

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY

All 2019 2018

All Journal Article Presentation

  • [Journal Article] Reply to: A genomic cause of cerebral palsy should not change the clinical classification.2018

    • Author(s)
      Takezawa Y, Kikuchi A, Haginoya K, Kure S.
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 5 Issue: 8 Pages: 1012-1012

    • DOI

      10.1002/acn3.585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09983
  • [Journal Article] Genomic analysis identifies masqueraders of full-term cerebral palsy2018

    • Author(s)
      Yusuke Takezawa, Atsuo Kikuchi, Kazuhiro Haginoya, Takehiko Inui, Noriko Togashi, Mai Anzai, Sato Suzuki-Muromoto, Takuya Miyabayashi, Wakaba Endo, Yukimune Okubo, Yasuko Kobayashi, Akira Onuma, Shigeo Kure, Yoko Aoki, Keiko Nakayama, Ryo Funayama, Matsuyuki Shirota, Saeko Yamamura-Suzuki
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 5 Issue: 5 Pages: 538-551

    • DOI

      10.1002/acn3.551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09983
  • [Presentation] Clinical and Genetic Analysis of 91 Patients with Childhood Onset Spastic Paraplegia2019

    • Author(s)
      Hginoya K, Takezawa Y, Kikuchi A, Haginoya K
    • Organizer
      American Academy of Cerebral Palsy and Developmental Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09983
  • [Presentation] 小児期発症頚性対麻痺91例の臨床的・遺伝学的解析2019

    • Author(s)
      萩野谷和裕、竹澤祐介、菊池敦生、呉繁夫
    • Organizer
      第61回小児神経学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09983
  • 1.  IINUMA Kazuie (80004927)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  YOKOYAMA Hiroyuki (40271952)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MUNAKATA Mitsutoshi (30312573)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  MIYABAYASHI S (20174203)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  大浦 敏博 (10176828)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MASUDA Yoshinobu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OGAWA E (60233409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NAKASATO Nobukazu (80207753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KURE Shigeo (10205221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TAKAHASHI Shoki (80148874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HIGANO Shuichi (20173148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAMURA Hajime (20333817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SHIRANE Reizo (30206297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MUGIKURA Shunji (20375017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NAGAFUCHI Masaaki (60004107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  松原 洋一 (00209602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  菊池 敦生 (30447156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 18.  YARITA Masaru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小島 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  黒羽根 郁夫
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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