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HAGINOYA Kazuhiro  萩野谷 和裕

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… Alternative Names

萩野 和裕  ハギノ カズヒロ

萩野谷 和裕  ハギノヤ カズヒロ

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Researcher Number 00208414
Affiliation (based on the past Project Information) *help 2016 – 2018: 東北大学, 医学系研究科, 非常勤講師
2002 – 2004: Department of Pediatrics, Associate Professor, 大学院・医学系研究科, 助教授
2000 – 2003: Tohoku University, Department of Pediatrics Lecturer, 大学院・医学系研究科, 講師
1997 – 1999: 東北大学, 医学部・附属病院, 講師
1998: 東北大学, 医学部附属病院, 講師 … More
1995: 東北大学, 医学部, 助手
1993: 東北大学, 医学部・附属病院, 助手
1988: 東北大学, 医 学部附属病院, 助手
1988: 東北大学, 医学部付属病院, 助手
1988: Tohoku Univ. Hospital, Department of Pediatrics, Instructor, 医学部附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Pediatrics / Pediatrics
Except Principal Investigator
Pediatrics / Radiation science
Keywords
Principal Investigator
てんかん / MELAS / ジストロフィン / 電撃痙攣 / カイニン酸 / 大脳皮質形成障害 / スライスパッチクランプ / 大脳皮質形成異常 / パッチクランプ法 / 接着因子 … More / 免疫組織化学 / ミトコンドリア病 / ミトコンドリアDNA / ヘテルプラスミー / A3243G変異 / ヘテロプラスミー / 変異率 / 培養線維芽細胞 / 高酸素 / 低酸素 / mitochondrial disease / mitochondrial DNA / heteroplasmy / A3243G / 抗カルジオリピン抗体 / 点頭てんかん / 抗カルジオリピン杭体 / western blottin / 免疫細織化学 / Eplepsy / West syndrome / anti-cardiolipin antibody / 脳性麻痺 / 遺伝子 / 満期産 / てんかん性脳症 / 遺伝性痙性対麻痺 / 遺伝学 / 脳神経疾患 / 臨床 / 小頭症 … More
Except Principal Investigator
ミトコンドリアDNA / 培養線維芽細胞 / mitochondrial DNA / cytochrome c oxidase deficiency / ヒスタミンH3受容体 / MEG / SEF / P300 / フェニルケトン尿症 / 遺伝子治療 / アデノウィルスベクター / チトクロームC酸化酵素欠損症 / ミトコンドリア / 電顕細胞化学 / 年齢依存性てんかん / 電撃けいれん / ペンチレンテトラゾールキンドリングモデル / テオフィリン誘発けいれん / 難治てんかん / 易けいれん性 / 幼弱動物実験 / テオフィリン / age dependent epilepsy / electroshock model / PTZ kindling model / theophylline induced seizures / Leigh脳症 / ATPase6 / ピルビン酸脱水素酵素欠損症 / チトクロームオキシダーゼ欠損症 / SURF1 / ピルビン酸脱水素欠損症 / ミトコンドリア病 / 変異率 / 低酸素 / 高酸素 / Leigh's disease / ATPase 6 / pyruvate dehydrogenase deficiency / SURF1 genes / PTZキンドリング / メチルヒスタミン / H1受容体ノックアウトマウス / PTZ kindling / methylhistamine / H3-receptor / 脳の代償機能 / 皮質形成異常 / てんかん波検出 / 大脳半球巨大嚢胞 / bandheterotopia / neuronal plasticity / cortical dysplasia / detection of epileptic activity / 中枢ヒスタミン / ヒスタミンH1受容体 / けいれん / 内因性ヒスタミン / H3受容体阻害薬 / 覚醒反応 / キンドリング / ペンチレンテトラゾール / thioperamide / central histamine / histamine H1 receptor / histamine H3 receptor / convulsion / intrinsic histamine / histamine H3 receptor antagonist / waking reaction / 熱性けいれん / Na+チャネル / K+チャネル / 電位依存性 / チャネル異常 / パッチクランプ / 温度変化 / 抗ヒスタミン薬 / NA+チャネル / Na^+チャネル / K^+チャネル / チャネル以上 / Febrile seizure / sodium channel / potassium channel / voltage-gated / abnormal channel / temperature change / antihistaminic agents / patch clamp / モヤモヤ病 / 脳腫瘍 / MRI-ASL法灌流画像 / MRI-ASL法 / 非侵襲的脳血流画像 / FAIR(Fluid attenuated inversion recovery)法 / moyamoya disease / brain tumor / MRI-ASL perfusion imaging / 日本語音声刺激 / 単語認識反応速度 / 音声刺激 / 聴覚誘発の【P_(300)】 / 語音識別 / Stimulation of Japanese words / ミトコンドリア電子伝達酵素欠損症 / 複合体IV欠損症 / 複合体I欠損症 / 免疫ブロット / CCO活性電顕 / 細胞毎のモザイク / ミトコンドリア電子伝達系酸素欠損症 / ミトコンドリアサイトパチー / cytochrome C oxidase 欠損症 / NADH-coQ reductase欠損症 / 免疫組織化学 / Digitonin 処理 / 組織特異性 / mitochondrial myopathy / NADH-ubiquinone oxidoreductase deficiency / immunoblotting Less
  • Research Projects

    (17 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (20 People)
  •  脳性麻痺1200例から見出した脳MRI正常群の原因遺伝子の同定Principal InvestigatorOngoing

    • Principal Investigator
      萩野谷 和裕
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Neurophysiological and molecular approach for evaluating mechanism of pathogenesis of febrile seizure

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Anticardolipin antibody and childhood epiepsyPrincipal Investigator

    • Principal Investigator
      HAGINOYA Kazuhiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  MRI-ASL perfusion imaging -evaluation in pediatric brain and moyamoya disease-

    • Principal Investigator
      TAKAHASHI Shoki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Tohoku University
  •  Research for development of new antiepileptic drug with wake-promoting effect

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Therapeutic research for mitochondrial diseasePrincipal Investigator

    • Principal Investigator
      HAGINOYA Kazuhiro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  ヒト大脳皮質異形成のてんかん源性獲得に関する組織学的、生理学的研究Principal Investigator

    • Principal Investigator
      萩野谷 和裕
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Development of a new antiepileptic agent without hypnotic effects

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Study of neuronal plasticity in children by biomagnetism

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  摘出組織を用いた大脳皮質形成障害のてんかん源性の解明Principal Investigator

    • Principal Investigator
      萩野 和裕
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Study on pathogenesis of Leigh's encephalomyelopathy

    • Principal Investigator
      MIYABAYASHI S
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  Neurophamacological basic research for intractable epilepsy in childhood

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  フェニルケトン尿症モデルマウスにおける遺伝子治療の基礎的研究

    • Principal Investigator
      松原 洋一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  ジストロフィンの脳内生理機能の解明Principal Investigator

    • Principal Investigator
      萩野谷 和裕
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  電顕組織科学の形態計測的手法によるチトクロームCオキシターゼ欠損の多 様性の解明

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Tohoku University
  •  Analysis of protein of electron-transfer enzymes in mitochondrial cytopathy

    • Principal Investigator
      MIYABAYASHI Shigeaki
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
      Tohoku University
  •  Development of a Stimulator for Elicitation of Auditory Evoked Potentials by Japanese Words.

    • Principal Investigator
      IINUMA Kazuie
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY

All 2018

All Journal Article

  • [Journal Article] Genomic analysis identifies masqueraders of full-term cerebral palsy2018

    • Author(s)
      Yusuke Takezawa, Atsuo Kikuchi, Kazuhiro Haginoya, Takehiko Inui, Noriko Togashi, Mai Anzai, Sato Suzuki-Muromoto, Takuya Miyabayashi, Wakaba Endo, Yukimune Okubo, Yasuko Kobayashi, Akira Onuma, Shigeo Kure, Yoko Aoki, Keiko Nakayama, Ryo Funayama, Matsuyuki Shirota, Saeko Yamamura-Suzuki
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 5 Pages: 538-551

    • DOI

      10.1002/acn3.551

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09983
  • [Journal Article] Reply to: A genomic cause of cerebral palsy should not change the clinical classification.2018

    • Author(s)
      Takezawa Y, Kikuchi A, Haginoya K, Kure S.
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 5 Pages: 1012-1012

    • DOI

      10.1002/acn3.585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09983
  • 1.  IINUMA Kazuie (80004927)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  YOKOYAMA Hiroyuki (40271952)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  MUNAKATA Mitsutoshi (30312573)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  MIYABAYASHI S (20174203)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  大浦 敏博 (10176828)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  MASUDA Yoshinobu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OGAWA E (60233409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  NAKASATO Nobukazu (80207753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KURE Shigeo (10205221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TAKAHASHI Shoki (80148874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  HIGANO Shuichi (20173148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAMURA Hajime (20333817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SHIRANE Reizo (30206297)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MUGIKURA Shunji (20375017)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NAGAFUCHI Masaaki (60004107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  松原 洋一 (00209602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  菊池 敦生 (30447156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  YARITA Masaru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小島 明
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  黒羽根 郁夫
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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