Tanizawa Yukio 谷澤幸生

… Alternative Names

TANIZAWA Yukio 谷澤幸生

谷沢幸生タニザワユキオ

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Researcher Number	00217142
Other IDs
Affiliation (Current)	2025: 山口大学, その他部局等, 学長
Affiliation (based on the past Project Information) *help	2017 – 2021: 山口大学, 大学院医学系研究科, 教授 2019: 山口大学, 医学(系)研究科(研究院), 教授 2012 – 2016: 山口大学, 医学(系)研究科(研究院), 教授 2015: 山口大学, 大学院医学系研究科, 教授 2005 – 2011: Yamaguchi University, School of Midicine, Professor, 大学院・医学系研究科, 教授 … More 2006: 山口大学, 大学院医学系研究科, 教授 2004: Yamaguchi University, Graduate School of Medicine, Professor, 医学部附属病院, 教授 2002 – 2004: 山口大学, 大学院・医学研究科, 教授 1998 – 2001: 山口大学, 医学部・附属病院, 講師 1998: 山口大学, 医学部附属病院, 講師 1995 – 1996: YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE ASSISTSNT PROFESSOR, 医学部・附属病院, 助手 1995: 山口大学, 医学部附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Metabolomics / Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Pathological medical chemistry / Biological Sciences / 内分泌・代謝学 Except Principal Investigator 内分泌・代謝学 / Metabolomics / Laboratory medicine / Biological Sciences / Metabolomics
Keywords	Principal Investigator 糖尿病 / インスリン分泌 / Wolfram症候群 / インスリン / 小胞体ストレス / 視神経萎縮 / diabetes mellitus / 膵β細胞 / Wolfram syndrome / β細胞 … More / 概日リズム / 時計遺伝子 / サーカディアンリズム / DBP / E4BP4 / 糖代謝 / 体内時計 / インスリン抵抗性 / ランゲルハンス氏島 / endoplasmic reticulum stress / insulin secretion / Diabetes Mellitus / Wolfram Syndrome / insulin / optic atrophy / 遺伝子 / 難聴 / HNF-1α / 小胞体 / ウォルフラム症候群 / pioglitazone / 脱分化 / 概日周期 / 代謝調節 / マクロファージ / 糖新生 / 肝糖代謝 / 肝臓 / Pioglitazone / Insulin / pancreatic β-cells / Endoplasmic reticulum stress / ノックアウトマウス / wolfram症候群 / β-cell / obesity / 肥満 / hypoglycemia / glutamate dehydrogenase / 低血糖症 / グルタミン酸脱水素酵素 / differentiation / pancreatic β-cell / ES cell / 分化 / ES細胞 / Optic Atrophy / ER stress / Mutation / Endoplasmic Reticulum / in situ hybridization / ERストレス / 遺伝子変異 / persistent hyperinsulinemic hypoglycemia of infancy / endoplasmic reticulum / PAX-4 / MODY / 転写因子 / Wolframの症候群 / 新生児低血糖症 / Pax4 / ストレス / アポトーシス / 分泌顆粒 / エクソサイトーシス / インスリン作用 / 小胞輸送 / SNARE関連蛋白 / グルコーストランスポーター / 糖輸送 / 遺伝素因 / スルホニル尿素受容体 / ATP感受性Kチャンネル / インスリン非依存型糖尿病 … More Except Principal Investigator インスリン / 糖尿病 / 膵β細胞 / インスリン分泌 / 糖輸送 / 小胞体ストレス / WFS1 / Wolfram syndrome / ウオルフラム症候群 / PI3キナーゼ / diabetes mellitus / GLUT4 / Diabetes / endoplasmic reticulum / Insulin / PDK1 / Grp1 / Akt / insulin / glucose transport / 糖輸送担体 / 細胞内ソーティング / キメラ蛋白 / 促通拡散輸送 / Wfs1 / 膵β細胞不全 / Wolfram症候群 / 脱分化 / 血液疾患 / パネル血清 / EBLM / 疾患別症例データベース / 内分泌疾患 / 疾患基準範囲 / 検査診断 / ケースレジストリ / 国際調査研究 / 事実に基づく臨床検査医学 / 臨床検査疫学 / 多変量解析 / 血液悪性疾患 / 検査診断学 / 多施設共同調査 / 検査診断支援 / 症例データベース / 基準値データベース / 検査疫学Web検索システム / 国際多施設共同調査 / 標準化 / 基準範囲 / 血液悪性腫瘍 / 膠原病 / 事実に基づく検査診断 / ELISA / C-peptide / constitutive secretion / islet beta cell / モデルマウス / インスリンプロモーター / 人工レポーター分子 / ELISA法 / C-ペプチド / 構成的分泌 / 膵β細胞量 / cell cycle / Endoplasmic reticulum stress / pancreatic B cell / Insulin secretion / glutamate / PPARa / GLUD1 / GDH / GPLD1 / ウェルナー症候群 / SNP / 細胞周期 / knock-out mice / pancreatic β cell / 視神経萎縮 / ER(endoplasmic reticulum) / アポトーシス / ノックアウトマウス / 小胞体 / PH domain / PI3 kinase / Glucose transport / ARNO / P13キナーゼ / PHドメイン / persistent hyperinsulinemic hypoglycemia of infancy / sulfonylurea receptor / PI3-kinase / adenovirus vector / ウイルスベクター / アデノウイルス / グリセロリン酸シャトル / GKラット / 遺伝子治療 / hepatocyte nuclear factor / 遺伝子導入 / 新生児低血糖症 / スルフォニル尿素受容体 / アデノウイルスベクター / sorting / chimeric protein / Caco-2 cells / GLUT5 / GLUT1 / glucose itasnporter / MDCK細胞 / Caco-2細胞 / 細胞内ソーテイング / キメラタンパク / dot blot hybridization / gene mutation / mitochondrial gene / insulin secretion / グルコキナーゼ / ミトコンドリア / 遺伝子異常 / Kチャネル / グリセロールリン酸シャトル / ミトコンドリア遺伝子 / fructose transport / molecular engineering / glucose transporter / フルクトース輸送 / 遺伝子工学 / グルコース輸送 / PKC / atypical PKC / DOC2b / Glut4 / sib-pair解析 / cdx-3 / IPF-1 / 転写因子 / 遺伝 / インスリン非依存型糖尿病 Less

From Cellular Stress to beta-cell failure and insulin resistance: Investigation of new mechanismsPrincipal Investigator
- Principal Investigator
  
  Tanizawa Yukio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Yamaguchi University
Development of a web-system for promotion of EBLM by building a clinical case bank with harmonized recording of lab data.
- Principal Investigator
  
  ICHIHARA Kiyoshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Yamaguchi University
The elucidation of the mechanisms underlying beta cell dedifferentiation and plasticity in diabetes
- Principal Investigator
  
  TANABE Katsuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
Peripheral Circadian Dysregulation and Metabolic DisordersPrincipal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
DOC2b regulates GLUT4 vesicle fusion mediated aPKC activation.
- Principal Investigator
  
  FUKUDA Naofumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
Investigation of the mechanism of beta-cell failure in diabetes using Wolfram Syndrome as a modelPrincipal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamaguchi University
Investigation of the mechanism of pancreatic beta-cell death underlying progressive nature of type 2 diabetes mellitus, aiming at the development of treatment strategy for the disease condition.Principal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamaguchi University
GLUT4小胞のインスリン・カルシウム依存性膜融合を促進する新規蛋白の同定と解析Principal Investigator
- Principal Investigator
  
  谷澤幸生
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
Investigation of insulin resistance-induced endoplasmic reticulum stress in the pancreatic β-cell and development of diabetes mellitusPrincipal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamaguchi University
ゲノム資源を用いた糖尿病発症遺伝素因としてのERストレス関連分子の探求Principal Investigator
- Principal Investigator
  
  谷澤幸生
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamaguchi University
Molecular Pathophysiology of Wolfram Syndrome and Endoplasmic Reticulum Stress-associated Pancreatic β-cell Failure.Principal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamaguchi University
The Development of the Model Mice Having the System that Easily Measuring their Pancreatic Islet Beta Cell Mass
- Principal Investigator
  
  MATSUBARA Atsushi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  YAMAGUCHI UNIVERSITY
Investigation of the roles of WFS1 and glutamate dehydorogenase on the pancreatic β-cell function and regulation of insulin secretionPrincipal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
Elucidation of diabetes-related genes
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Generation of Wolfram syndrome mice, aiming at development of new therapeutics for diabetes through preserving pancreatic beta cells
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Metabolomics
- Research Institution
  Tohoku University
  Yamaguchi University
In vitro induction of pancreatic β-cell development from mouse embryonic stem cellsPrincipal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
Elucidation of molecular pathophysiology and development of the methods for molecular diagnosis of the disease associated with WFS1 gene mutations.Principal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamaguchi University
Intracellular sorting of glucose transporter and insulin action
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  内分泌・代謝学
- Research Institution
  Yamaguchi University
Regulation of Pacreatic β-cell Function by Transcription Factors.Principal Investigator
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
treatment using adenovirus vector
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Yamaguchi University
スルホニル尿素受容体の機能およびインスリン非依存型糖尿病における役割の解析Principal Investigator
- Principal Investigator
  
  谷澤幸生
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Yamaguchi University
促通拡散ヘキソーストランスポータアイソフォームの構造・機能相関
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamaguchi University
II型糖尿病の発症機構におけるインスリン遺伝子転写因子の役割
- Principal Investigator
  
  加来浩平
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Yamaguchi University
Sorting mechanismof glucose transporters in mammalian cells.
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Yamaguchi University School of Medicine
MOLECULAR ANALYSIS OF STRUCTURE-FUNCTION RELATIONSHIP OF GLUCOSE TRANSPORTER AND INSULIN ACTION
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  YAMAGUCHI UNIVERSITY
Genes involved in insulin secretion and improvement of detection method for gene mutations in diabetic patients
- Principal Investigator
  
  OKA Yoshitomo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  Yamaguchi University School of Medicine

[Book] 内分泌・糖尿病・代謝内科2017
- Author(s)
  椎木幾久子、田部勝也、谷澤幸生
- Total Pages
  174
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16K09752
[Book] 月刊　糖尿病2017
- Author(s)
  椎木幾久子、田部勝也、谷澤幸生
- Total Pages
  9
- Publisher
  医学出版
- ISBN
  9784287820971
- Data Source
  KAKENHI-PROJECT-16K09752
[Book] 月刊　糖尿病2017
- Author(s)
  田部勝也、松永仁恵、椎木幾久子、谷澤幸生
- Total Pages
  9
- Publisher
  医学出版
- ISBN
  9784287820988
- Data Source
  KAKENHI-PROJECT-16K09752
[Book] 糖尿病UP DATE賢島セミナー2016　2型糖尿病への効果的なインスリン治療とは　病状・病態に応じたシームレスな管理・治療2017
- Author(s)
  谷澤幸生（堀田饒、清野裕、門脇孝、羽田勝計、中村二郎　編）
- Total Pages
  248
- Publisher
  メディカル・ジャーナル社
- ISBN
  9784908437090
- Data Source
  KAKENHI-PROJECT-15H04849
[Book] 難治性内分泌代謝疾患Update　ウォルフラム（Wolfram）症候群2015
- Author(s)
  谷澤幸生、松永仁恵
- Total Pages
  175
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15H04849
[Book] その他の糖尿病の見分け方　糖尿病学の進歩（日本糖尿病学会編）　第46集2012
- Author(s)
  谷澤幸生
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-23390080
[Book] 糖尿病の遺伝子診断・治療と生命倫理糖尿病ナビゲータ第2版(編集門脇孝)2010
- Author(s)
  谷澤幸生
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20390093
[Book] グルコキナーゼ遺伝子異常糖尿病ナビゲータ第2版(編集門脇孝)2010
- Author(s)
  太田康晴、谷澤幸生
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20390093
[Book] 糖尿病ナビゲータ(編集門脇孝)(糖尿病の遺伝子診断・治療と生命倫理)第2版2010
- Author(s)
  谷澤幸生(分担)
- Total Pages
  473
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20390093
[Book] 糖尿病学基礎と臨床(門脇孝他編集)(分担執筆)2007
- Author(s)
  谷澤幸生, 他
- Total Pages
  1373
- Publisher
  西村書店
- Data Source
  KAKENHI-PROJECT-18390103
[Book] 遺伝性症候群に伴う糖尿病最新糖尿病学-基礎と臨床-(垂井清一郎・門脇孝・花房俊昭編集) 214-225, 20062006
- Author(s)
  谷澤幸生
- Total Pages
  781
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-18390103
[Book] 糖尿病の最新医療 Wolfram症候群(堀田饒他編)2005
- Author(s)
  谷澤幸生(分担執筆)
- Total Pages
  390
- Publisher
  先端医療技術研究所
- Data Source
  KAKENHI-PROJECT-16390096
[Book] 糖尿病の最新医療(先端医療シリーズ32)2005
- Author(s)
  谷澤幸生, 他
- Total Pages
  390
- Publisher
  先端医療技術研究所
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390096
[Book] 糖尿病の最新医療(先端医療シリーズ32)2005
- Author(s)
  谷澤幸生他
- Total Pages
  390
- Publisher
  先端医療技術研究所
- Data Source
  KAKENHI-PROJECT-16390096
[Book] 糖尿病の最新医療(Wolfram症候群、分担執筆)(堀田饒他編)2005
- Author(s)
  谷澤幸生(分担執筆)
- Total Pages
  390
- Publisher
  先端医療技術研究所
- Data Source
  KAKENHI-PROJECT-16012244
[Journal Article] Metabolic state switches between morning and evening in association with circadian clock in non‐diabetic humans2022
- Author(s)
  Fujimoto Ruriko、Ohta Ysuharu、Masuda Konosuke、Taguchi Akihiko、Akiyama Masaru、Yamamoto Kaoru、Nakabayashi Hiroko、Nagao Yuko、Matsumura Takuro、Hiroshige Syunsuke、Kajimura Yasuko、Akashi Makoto、Tanizawa Yukio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 9 Pages: 1496-1505
- DOI
  10.1111/jdi.13810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-19H03710, KAKENHI-PROJECT-22K08626
[Journal Article] Deficiency of WFS1 leads to the impairment of AVP secretion under dehydration in male mice.2021
- Author(s)
  Kurimoto J, Takagi H, Miyata T, Hodai Y, Kawaguchi Y, Hagiwara D, Suga H, Kobayashi T, Sugiyama M, Onoue T, Ito Y, Iwama S, Banno R, Tanabe K, Tanizawa Y, Arima H.
- Journal Title
  
  Pituitary
  
  Volume: in press Issue: 4 Pages: 582-588
- DOI
  10.1007/s11102-021-01135-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08887, KAKENHI-PROJECT-19H03710
[Journal Article] A patient with sudden hearing loss induced by propylthiouracil2021
- Author(s)
  Tanabe Katsuya、Nishimura Shogo、Sugahara Kazuma、Yamashita Hiroshi、Tanizawa Yukio
- Journal Title
  
  Heliyon
  
  Volume: 7 Issue: 2 Pages: e06196-e06196
- DOI
  10.1016/j.heliyon.2021.e06196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09321, KAKENHI-PROJECT-20K08887, KAKENHI-PROJECT-20K09733, KAKENHI-PROJECT-19H03710
[Journal Article] Liver-specific dysregulation of clock-controlled output signal impairs energy metabolism in liver and muscle2021
- Author(s)
  Matsumura T, Ohta Y, Taguchi A, Hiroshige S, Kajimura Y, Fukuda N, Yamamoto K, Nakabayashi H, Fujimoto R, Yanai A, Shinoda K, Watanabe K, Mizukami Y, Kanki K, Shiota G, Tanizawa Y.
- Journal Title
  
  Biochem Biophys Res Commun .
  
  Volume: 534 Pages: 415-421
- DOI
  10.1016/j.bbrc.2020.11.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08517, KAKENHI-PROJECT-19K02318, KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-18K16255, KAKENHI-PROJECT-20K22781, KAKENHI-PROJECT-19H03710, KAKENHI-PROJECT-18K11128, KAKENHI-PROJECT-21K08644
[Journal Article] Long-term safety and efficacy of alogliptin, a DPP-4 inhibitor, in patients with type 2 diabetes: a 3-year prospective, controlled, observational study (J-BRAND Registry)2021
- Author(s)
  Ueki K, Tanizawa Y, Nakamura J, Yamada Y, Inagaki N, Watada H, Shimomura I, Nishimura R, Miyoshi H, Abiko A, Katagiri H, Hayashi M, Shimada A, Naruse K, Fujimoto S, Fujiwara M, Shikata K, Okada Y, Araki E, Yamazaki T, Kadowaki T; J-BRAND Registry Group.
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 9 Issue: 1 Pages: e001787-e001787
- DOI
  10.1136/bmjdrc-2020-001787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-19K10121, KAKENHI-PROJECT-19H03710, KAKENHI-PROJECT-21K08533, KAKENHI-PROJECT-17K09698
[Journal Article] Importance of Intestinal Environment and Cellular Plasticity of Islets in the Development of Postpancreatectomy Diabetes.2021
- Author(s)
  Fukuda T, Bouchi R, Takeuchi T, Amo-Shiinoki K, Kudo A, Tanaka S, Tanabe M, Akashi T, Hirayama K, Odamaki T, Igarashi M, Kimura I, Tanabe K, Tanizawa Y, Yamada T, Ogawa Y
- Journal Title
  
  Diabetes Care
  
  Volume: 44(4) Issue: 4 Pages: 1002-1011
- DOI
  10.2337/dc20-0864
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08887, KAKENHI-PROJECT-20K21627, KAKENHI-PROJECT-19H01054, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-18K08516, KAKENHI-PROJECT-19K09041, KAKENHI-PROJECT-19H03710, KAKENHI-PROJECT-21K08581
[Journal Article] Soluble Interleukin-2 Receptor Index Predicts Outcomes After Cord Blood Transplantation2021
- Author(s)
  Kajimura Y, Nakamura Y, Tanaka Y, Tanaka M, Yamamoto K, Matsuguma M, Tokunaga Y, Yujiri T, Tanizawa Y.
- Journal Title
  
  Transplant Proc .
  
  Volume: 53 Issue: 1 Pages: 379-385
- DOI
  10.1016/j.transproceed.2020.03.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22781, KAKENHI-PROJECT-18K08358, KAKENHI-PROJECT-19H03710
[Journal Article] Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes.2021
- Author(s)
  Amo-Shiinoki K, Tanabe K, Hoshii Y, Matsui H, Harano R, Fukuda T, Takeuchi T, Bouchi R, Takagi T, Hatanaka M, Takeda K, Okuya S, Nishimura W, Kudo A, Tanaka S, Tanabe M, Akashi T, Yamada T, Ogawa Y, Ikeda E, Nagano H, Tanizawa Y.
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 1 Pages: 143791-143791
- DOI
  10.1172/jci.insight.143791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09843, KAKENHI-PROJECT-19K07506, KAKENHI-PROJECT-19K09041, KAKENHI-PROJECT-20K08887, KAKENHI-PROJECT-20K08915, KAKENHI-PROJECT-20K21627, KAKENHI-PROJECT-19H01055, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-18K08516, KAKENHI-PROJECT-19H03710
[Journal Article] Adrenomedullin has a cytoprotective role against endoplasmic reticulum stress for pancreatic β‐cells in autocrine and paracrine manners2020
- Author(s)
  Suetomi Risa、Ohta Yasuharu、Akiyama Masaru、Matsumura Takuro、Taguchi Akihiko、Yamamoto Kaoru、Kamatani Takashi、Tanizawa Yukio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 4 Pages: 823-833
- DOI
  10.1111/jdi.13218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08517, KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-19H03710
[Journal Article] 【インスリン分泌機構とその異常】時計遺伝子とインスリン分泌異常について2020
- Author(s)
  田口昭彦, 谷澤幸生
- Journal Title
  
  月刊糖尿病
  
  Volume: 12(7) Pages: 40-46
- Data Source
  KAKENHI-PROJECT-19H03710
[Journal Article] 【全容が解き明かされつつある糖尿病遺伝素因】ウォルフラム症候群について2020
- Author(s)
  椎木幾久子, 田部勝也, 谷澤幸生
- Journal Title
  
  月刊糖尿病
  
  Volume: 12(6) Pages: 47-54
- Data Source
  KAKENHI-PROJECT-19H03710
[Journal Article] 時計遺伝子と糖代謝2020
- Author(s)
  田口昭彦, 太田康晴, 谷澤幸生
- Journal Title
  
  日本体質医学会雑誌
  
  Volume: 82(2) Pages: 73-82
- NAID
  40022281033
- Data Source
  KAKENHI-PROJECT-19H03710
[Journal Article] Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial2018
- Author(s)
  Araki Eiichi、Yamashita Shizuya、Arai Hidenori、Yokote Koutaro、Satoh Jo、Inoguchi Toyoshi、Nakamura Jiro、Maegawa Hiroshi、Yoshioka Narihito、Tanizawa Yukio、Watada Hirotaka、Suganami Hideki、Ishibashi Shun
- Journal Title
  
  Diabetes Care
  
  Volume: 41 Issue: 3 Pages: 538-546
- DOI
  10.2337/dc17-1589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-17H02100, KAKENHI-PROJECT-18K08482, KAKENHI-PROJECT-17H04201, KAKENHI-PROJECT-17K19643
[Journal Article] インスリン抵抗性研究の最前線ー肝におけるインスリン抵抗性ー2018
- Author(s)
  太田康晴、谷澤幸生
- Journal Title
  
  最新医学
  
  Volume: 73 Pages: 24-29
- Data Source
  KAKENHI-PROJECT-15H04849
[Journal Article] Remission of hyperglycemia after withdrawal of oral antidiabetic drugs in Japanese patients with early-stage type 2 diabetes2018
- Author(s)
  Hirukawa Hidenori、Hashiramoto Mitsuru、Tanizawa Yukio、Kaku Kohei、Pioglitazone and Sulfonylurea Remission from Type 2 Diabetes Mellitus and Anti-Atherosclerosis in Japan (PREVENT-J) study group
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in press Issue: 5 Pages: 1119-1127
- DOI
  10.1111/jdi.12813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04849
[Journal Article] Activation of GLP-1 receptor signaling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.2018
- Author(s)
  Kondo M, Tanabe K, Amo-Shiinoki K, Hatanaka M, Morii T, Takahashi H, Seino S, Yamada Y, Tanizawa Y
- Journal Title
  
  Diabetologia
  
  Volume: 61 Issue: 10 Pages: 2189-2201
- DOI
  10.1007/s00125-018-4679-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08516, KAKENHI-PROJECT-18H02864, KAKENHI-PROJECT-16K09749, KAKENHI-PROJECT-16K09752
[Journal Article] Molecular clock as a regulator of β-cell function2018
- Author(s)
  Taguchi Akihiko、Ohta Yasuharu、Tanizawa Yukio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 9 Issue: 3 Pages: 453-456
- DOI
  10.1111/jdi.12835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-18K08517
[Journal Article] Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function.2017
- Author(s)
  Ohta Y., Taguchi A., Matsumura T., Nakabayashi H., Akiyama M., Yamamoto K., Fujimoto R., Suetomi R., Yanai A., Shinoda K., Tanizawa Y.
- Journal Title
  
  EBioMedicine
  
  Volume: 18 Pages: 146-156
- DOI
  10.1016/j.ebiom.2017.03.040
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-26460489, KAKENHI-PROJECT-16H05118
[Journal Article] Wolfram症候群の臨床像と遺伝的特徴2017
- Author(s)
  田部勝也、松永仁恵、椎木幾久子、谷澤幸生
- Journal Title
  
  月刊糖尿病
  
  Volume: 9 Pages: 45-53
- Data Source
  KAKENHI-PROJECT-15H04849
[Journal Article] Causes of death in Japanese patients with diabetes based on the results of a survey of 45,708 cases during 2001-2010: Report of the Committee on Causes of Death in Diabetes Mellitus2017
- Author(s)
  Nakamura Jiro、Kamiya Hideki、Haneda Masakazu、Inagaki Nobuya、Tanizawa Yukio、Araki Eiichi、Ueki Kohjiro、Nakayama Takeo
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 8 Issue: 3 Pages: 397-410
- DOI
  10.1111/jdi.12645
- NAID
  40021217934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-15K09394
[Journal Article] Wolfram症候群2017
- Author(s)
  椎木幾久子、田部勝也、谷澤幸生
- Journal Title
  
  月刊糖尿病
  
  Volume: 9 Pages: 36-44
- Data Source
  KAKENHI-PROJECT-15H04849
[Journal Article] Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation2017
- Author(s)
  Hatanaka Masayuki、Anderson-Baucum Emily、Lakhter Alexander、Kono Tatsuyoshi、Maier Bernhard、Tersey Sarah A.、Tanizawa Yukio、Evans-Molina Carmella、Mirmira Raghavendra G.、Sims Emily K.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 3758-3758
- DOI
  10.1038/s41598-017-03869-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-15K09390
[Journal Article] Interorgan Crosstalk Contributing to β-Cell Dysfunction.2017
- Author(s)
  Tanabe K., Amo-Shiinoki K., Hatanaka M., Tanizawa Y.
- Journal Title
  
  J Diabetes Res.
  
  Volume: 2017 Pages: 1-8
- DOI
  10.1155/2017/3605178
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-16K09752, KAKENHI-PROJECT-15K21198, KAKENHI-PROJECT-15K09390
[Journal Article] Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial2017
- Author(s)
  Ueki K, Sasako T, Okazaki Y, Kato M, Okahata S, Katsuyama H, Haraguchi M, Morita A, Ohashi K, Hara K, Morise A, Izumi K, Ishizuka N, Ohashi Y, Noda M, Kadowaki T
- Journal Title
  
  Lancet Diabetes Endocrinol
  
  Volume: 5 Issue: 12 Pages: 951-964
- DOI
  10.1016/s2213-8587(17)30327-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-15H04849
[Journal Article] 少遺伝子型 (oligogenic) 糖尿病の解析 (2) Wolfram症候群と糖尿病2016
- Author(s)
  田部勝也、谷澤幸生
- Journal Title
  
  Diabetes Frontier
  
  Volume: 27 Pages: 466-471
- Data Source
  KAKENHI-PROJECT-15H04849
[Journal Article] Altered expression of circadian clock genes during peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor.2015
- Author(s)
  Sugiyama A, Yujiri T, Tanaka M, Tanaka Y, Nakamura Y, Tanizawa Y.
- Journal Title
  
  Chronobiology International
  
  Volume: 32 Issue: 7 Pages: 934-941
- DOI
  10.3109/07420528.2015.1053910
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461421, KAKENHI-PROJECT-15H04849
[Journal Article] Impairment of Visual Function and Retinal ER Stress Activation in Wfs1-Deficient Mice2014
- Author(s)
  Bonnet Wersinger D., Benkafadar N., Jagodzinska J., Hamel C., Tanizawa Y., Lenaers G., Delettre C
- Journal Title
  
  PLoS One
  
  Volume: 9(5) Issue: 5 Pages: e97222-e97222
- DOI
  10.1371/journal.pone.0097222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1β gene expression in pancreatic islet β-cells2013
- Author(s)
  Nakabayashi H, Ohta Y, Yamamoto M, Susuki Y, Taguchi A, Tanabe K, Kondo M, Hatanaka M, Nagao Y, Tanizawa Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 434 Issue: 2 Pages: 370-5
- DOI
  10.1016/j.bbrc.2013.03.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590984, KAKENHI-PROJECT-23390080, KAKENHI-PROJECT-25461357
[Journal Article] Wolfram症候群における膵β細胞の量的、質的異常2013
- Author(s)
  田部勝也、秋山　優、幡中雅行、近藤　学、松永仁恵、谷澤幸生
- Journal Title
  
  Diabetes Frontier
  
  Volume: 24 Pages: 519-526
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] A sibling case of Wolfram syndrome with a novel mutation Y652X in WFS12013
- Author(s)
  Iwasaki N., Fukawa K., Matsuo M., Urano M., Watanabe M., Ono Y., Tanabe K., Tanizawa Y., Ogata M., Ide R., Takizawa M., Nagata S., Osawa M., Uchigata Y., Saito K.
- Journal Title
  
  Diabetology International
  
  Volume: 5 Issue: 2 Pages: 148-153
- DOI
  10.1007/s13340-013-0145-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080, KAKENHI-PROJECT-25461357
[Journal Article] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1 β gene expression in pancreatic islet β -cells2013
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M.,Hatanaka M., Nagao Y., Tanizawa Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 434(2) Pages: 370-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] Wolfram症候群2013
- Author(s)
  谷澤幸生
- Journal Title
  
  医学のあゆみ
  
  Volume: 244 Pages: 1035-1039
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] ウォルフラム症候群2012
- Author(s)
  谷澤幸生
- Journal Title
  
  内科
  
  Volume: 109 Pages: 1316-1318
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] Glucose and Fatty Acids Synergize to Promote B-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation2011
- Author(s)
  Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Méneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA
- Journal Title
  
  PLoS ONE
  
  Volume: 6(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] Activation of the unfolded protein response in primary acute myeloid leukemia cells2011
- Author(s)
  Tanimura A., Yujiri T., Tanaka Y., Tanaka M., Mitani N., Nakamura Y., Ariyoshi K., Tanizawa Y
- Journal Title
  
  Int J Hematol
  
  Volume: 94(3) Pages: 300-2
- NAID
  10029694452
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic β-cells.2011
- Author(s)
  Hatanaka M, Tanabe K, Yanai A, Ohta Y, Kondo M, Akiyama M, Shinoda K, Oka Y, Tanizawa Y
- Journal Title
  
  Hum Mol Genet. 20
  
  Pages: 1274-1284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Wolfram症候群月刊糖尿病2011
- Author(s)
  松永仁恵、谷澤幸生
- Journal Title
  
  3:4
  
  Pages: 50-57
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic β-cells2011
- Author(s)
  Hatanaka M, Tanabe K, Yanai A, Ohta Y, Kondo M, Akiyama M, Shinoda K, Oka Y, Tanizawa Y
- Journal Title
  
  Hum Mol Genet
  
  Volume: 20(7) Pages: 1274-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080
[Journal Article] Glucose and Fatty Acids Synergize to Promote β-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation.2011
- Author(s)
  Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Meneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA.
- Journal Title
  
  PLoS ONE 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] 加齢がインスリン分泌に与える影響2011
- Author(s)
  太田康晴、谷澤幸生
- Journal Title
  
  最新医学 66
  
  Pages: 22-27
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] WFS1遺伝子と糖尿病2010
- Author(s)
  谷澤幸生
- Journal Title
  
  医学のあゆみ 232
  
  Pages: 1209-1210
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] 膵β細胞死2010
- Author(s)
  太田康晴、谷澤幸生
- Journal Title
  
  臨床検査 54
  
  Pages: 1040-1047
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Alteration of adipokines during peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor.2009
- Author(s)
  Tanaka Y, Yujiri T, Tanaka M, Mitani N, Tanimura A, Tanizawa Y
- Journal Title
  
  J Clin Apher. 24
  
  Pages: 205-208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Wolfram syndrome 1 (Wfs1) mRNA expression in the normal mouse brain during postnatal development.2009
- Author(s)
  Kawano J, Fujinaga R, Yamamoto-Hanada K, Oka Y, Tanizawa Y, Shinoda K.
- Journal Title
  
  Neurosci Res. 64
  
  Pages: 213-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] DOC2b is a SNARE regulator of glucose-stimulated delayed insulin secretion.2009
- Author(s)
  Miyazaki M, Emoto M, Fukuda N, Hatanaka M, Taguchi A, Miyamoto S, Tanizawa Y
- Journal Title
  
  Biochem Biophys Res Commun. 384
  
  Pages: 461-465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] DOC2B : a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes.2009
- Author(s)
  Fukuda N, Emoto M, Nakamori Y, Taguchi A, Miyamoto S, Uraki S, Oka Y, Tanizawa Y
- Journal Title
  
  Diabetes. 58
  
  Pages: 377-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells.2009
- Author(s)
  Tanimura A, Yujiri T, Tanaka Y, Hatanaka M, Mitani N, Nakamura Y, Mori K, Tanizawa Y
- Journal Title
  
  Leuk Res 33
  
  Pages: 924-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Increased insulin demand promotes while pioglitazone prevents pancreatic beta cell apoptosis in Wfs1 knockout mice.2009
- Author(s)
  Akiyama M, Hatanaka M, Ohta Y, Ueda K, Yanai A, Uehara Y, Tanabe K, Tsuru M, Miyazaki M, Saeki S, Saito T, Shinoda K, Oka Y, Tanizawa Y
- Journal Title
  
  Diabetologia. 52
  
  Pages: 653-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system.2008
- Author(s)
  Kawano J, Tanizawa Y Shinoda K.
- Journal Title
  
  J Comp Neurol. 510
  
  Pages: 1-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Identification of Glypican3 as a novel GLUT4-binding protein.2008
- Author(s)
  Taguchi A, Emoto M, Okuya S, Fukuda N, Nakamori Y, Miyazaki M, Miyamoto S, Tanabe K, Aburatani H, Oka Y, Tanizawa Y
- Journal Title
  
  Biochem Biophys Res Commun. 369
  
  Pages: 1204-1208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390093
[Journal Article] Wolfram syndrome 1 (Wfs1) gene expression in the normal mouse visual system.2008
- Author(s)
  Kawano J, Tanizawa Y, Shinoda K.
- Journal Title
  
  I Comp Neurol. 510(1)
  
  Pages: 1-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390103
[Journal Article] Estrogen Receptor alpha Regulates Insulin Sensitivity through IRS-1 Tyrosine Phosphorylation in Mature 3T3-L1 Adipocytes.2006
- Author(s)
  Muraki K, Okuya S, Tanizawa Y
- Journal Title
  
  Endocrine J. 53(6)
  
  Pages: 841-851
- NAID
  130004443276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390103
[Journal Article] Wolfram Syndrome2005
- Author(s)
  Tanizawa Y
- Journal Title
  
  New Frontier of Diabetes
  
  Pages: 390-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390096
[Journal Article] Disruption of the WFS1 gene in mice causes progressive beta-cell loss and impaired stimulus-secretion coupling in insulin secretion.2004
- Author(s)
  Ishihara H, Takeda S, Tamura A, Takahashi R, Yamaguchi S, Takei D, Yamada T, Inoue H, Soga H, Katagiri H, Tanizawa Y, Oka Y.
- Journal Title
  
  Hum Mol Genet. 13
  
  Pages: 1159-1170
- Data Source
  KAKENHI-PROJECT-13204062
[Journal Article] Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation.2004
- Author(s)
  Anno T, Uehara S, Katagiri H, Ohta Y, Ueda K, Mizuguchi H, Moriyama Y, Oka Y, Tanizawa Y.
- Journal Title
  
  Am J Physiol. 286
- Data Source
  KAKENHI-PROJECT-13204062
[Journal Article] Genetic variations at urotensin II and urotensin II receptor genes and risk of type 2 diabetes mellitus in Japanese.2004
- Author(s)
  Suzuki S, Zong Wenyi, Hirai M, Hinokio Y, Suzuki C, Yamada T, Yoshizumi S, Suzuki M, Tanizawa Y, Matsunami A, Oka Y.
- Journal Title
  
  Peptides 25
  
  Pages: 1803-1808
- Data Source
  KAKENHI-PROJECT-13204062
[Presentation] ペマフィブラートが2型糖尿病患者の左室拡張能に与える効果の検討2022
- Author(s)
  太田康晴，田口昭彦，秋山優，山本薫，中林容子，廣重俊典，畠中諒子，和田靖明，山本健，矢野雅文，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Txnip preserves brown fat innate thermogenic activity2022
- Author(s)
  MENG ZOU，田部勝也，椎木幾久子，田口昭彦，河野大輔，北村忠弘，奥屋茂，増谷弘，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] スダチチンによるインスリン分泌促進機構の解明2022
- Author(s)
  畠中諒子，田口昭彦，増田香之介，尾野孝夫，對馬千沙都，二階堂隆人，高岡彰子，太田康晴，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] シンポジウム（S2）機能的な膵β 細胞維持に向けた膵島研究の最前線　糖尿病における膵島細胞の可塑性と脱分化2022
- Author(s)
  椎木幾久子，田部勝也，幡中雅行，奥屋茂，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] シンポジウム（S19）臨床・基礎におけるグルカゴン研究の進歩　グルカゴン需要増大に対するα 細胞の挙動と細胞量調節機構2022
- Author(s)
  田部勝也，椎木幾久子，谷澤幸生，奥屋茂
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 糖尿病におけるβ 細胞不全の分子メカニズムに関する研究：From A Rare Disease to the Common Pathway2022
- Author(s)
  谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 非糖尿病者における糖代謝の概日リズムに基づいた時計遺伝子モニタリングの有用性の検討2021
- Author(s)
  藤本留理子，太田康晴，松村卓郎，田口昭彦，山本薫，廣重俊典，秋山優，竹田孔明，明石真，谷澤幸生
- Organizer
  第２０回日本先進糖尿病治療研究会　第１８回１型糖尿病研究会（合同開催）
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 八味地黄丸は熱産生を亢進し，抗肥満作用を有する2021
- Author(s)
  香川正太，田部勝也，廣村信，古賀貴之，椎木幾久子，鈴木早織，水津菜月，大嶺貴亮，濱地桜子，奥屋茂，木村郁子，谷澤幸生，長島史裕
- Organizer
  第６４回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 糖尿病基礎研究最前線　「時計遺伝子による代謝制御はどこまで糖尿病に関わっているのか」を探求する2021
- Author(s)
  太田康晴，田口昭彦，松村卓郎，藤本留理子，中林容子，廣重俊典，梶邑泰子，山本薫，神吉けい太，汐田剛史，明石真，谷澤幸生
- Organizer
  第６４回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] シンポジウム膵β細胞の発生，分化と量の調節機構　糖尿病における膵島細胞の可塑性と脱分化2021
- Author(s)
  田部勝也，椎木幾久子，幡中雅行，谷澤幸生
- Organizer
  第６４回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 出力系時計遺伝子DBPの欠損は骨格筋のインスリン感受性を亢進させる2021
- Author(s)
  廣重俊典，太田康晴，田口昭彦，山本薫，松村卓郎，梶邑泰子，藤本留理子，谷澤幸生
- Organizer
  第６４回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 出力系時計遺伝子Dbpを欠損したマウスでは骨格筋のインスリン感受性の亢進を認める2021
- Author(s)
  廣重俊典，太田康晴，田口昭彦，山本薫，松村卓郎，梶邑泰子，谷澤幸生
- Organizer
  第７１回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] ヒトにおける糖代謝の概日リズムと時計遺伝子との関連性の検討2020
- Author(s)
  松村卓郎，太田康晴，藤本留理子，田口昭彦，山本薫，廣重俊典，竹田孔明，明石真，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 時計遺伝子E4BP4によるマクロファージの炎症制御機構の解明2020
- Author(s)
  梶邑泰子, 田口昭彦, 山本薫, 太田康晴, 谷澤幸生
- Organizer
  第70回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] β-cell dedifferentiation is involved in progression of thpe 2 diabetes (T2D)2020
- Author(s)
  Shiinoki-Amo K, Tanabe K, Hatanaka M, Okuya S, Fukuda T, Takeuchi T, Bouchi R, Yamada Y, Ogawa Y, Tanizawa Y
- Organizer
  American Diabetes Association 80th Scientific Sessions. (Virtual Meeting)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 膵β細胞脱分化は2型糖尿病の病態進展に関連する2020
- Author(s)
  田部勝也，椎木幾久子，幡中雅行，谷澤幸生
- Organizer
  第93回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 体内時計による代謝制御と糖尿病2020
- Author(s)
  太田康晴，田口昭彦，松村卓郎，藤本留理子，秋山優，福田尚文，山本薫，神吉けい太，汐田剛史，水上洋一，篠田晃，柳井章江，明石真，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 非糖尿病者における糖代謝の概日リズムとそのメカニズムの検討2020
- Author(s)
  藤本留理子，太田康晴，松村卓郎，田口昭彦，山本薫，廣重俊典，秋山優，竹田孔明，明石真，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Importance of Intestinal Environment and Cellular Plasticity of Beta Cells in the Development of Post-Pancreatectomy Diabetes.2020
- Author(s)
  Bouchi R, Fukuda T, Takeuch T, Shiinoki-Amo K, Tanabe K, Tanizawa Y, Yamada T, Ogawa Y
- Organizer
  American Diabetes Association 80th Scientific Sessions. (Virtual Meeting)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 健常者における糖代謝の概日リズムとそのメカニズムの検討2020
- Author(s)
  藤本留理子, 太田康晴, 松村卓郎, 田口昭彦, 山本薫, 廣重俊典, 秋山優, 竹田孔明, 明石真, 谷澤幸生
- Organizer
  第93回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 膵β細胞脱分化は2型糖尿病の病態進展に関連する2020
- Author(s)
  椎木幾久子，田部勝也，幡中雅行，奥屋茂，福田達也，竹内崇人，坊内良太郎，山田哲也，小川佳宏，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 出力系時計遺伝子E4BP4の肝特異的過剰発現は骨格筋でのインスリン感受性を低下させる2020
- Author(s)
  太田康晴，松村卓郎，田口昭彦，福田尚文，山本薫，柳井章江，秋山優，藤本留理子，神吉けい太，汐田剛史，水上洋一，篠田晃，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 糖尿病の病態解明と治療の進歩UPDATE2020
- Author(s)
  谷澤幸生
- Organizer
  第70回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 体内時計と代謝制御機構2019
- Author(s)
  太田康晴、田口昭彦、松村卓郎、福田尚文、山本薫、柳井章江、秋山優、藤本留理子、神吉けい太、汐田剛史、水上洋一、篠田晃、谷澤幸生
- Organizer
  第69回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] インスリンシグナル伝達病と希少・難治疾患における糖尿病 Wolfram 症候群 UP TO DATE2019
- Author(s)
  谷澤幸生、田部勝也、椎木幾久子、松永仁恵
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 時計遺伝子 E4BP4, DBPと膵β細胞機能との関連2019
- Author(s)
  田口昭彦、太田康晴、松村卓郎、梶邑泰子、山本薫、中林容子、藤本留理子、秋山優、末冨吏佐、柳井章江、篠田晃、谷澤幸生
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Metabolic dysregulation by cellular stress is implicated in the dedifferentiation and dysfunction of pancreatic beta cells.2019
- Author(s)
  Tanizawa Y, Tanabe K, Amo-Shinoki K.
- Organizer
  55th Annual Meeting of European Association for the Study of Diabetes (EASD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Activation of GLP-1 receptor signalling prevents beta cell dedifferentiation in a mouse model of Wolfram syndrome through modulating Txnip expression.2019
- Author(s)
  Tanabe K, Amo-Shinoki K, Kondo M, Hatanaka M, Masatani M, Tanizawa Y.
- Organizer
  79th American Diabetes Association Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 糖尿病克服への体質医学の挑戦-β細胞不全をめぐって-2019
- Author(s)
  谷澤幸生
- Organizer
  第69回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Wolfram症候群をモデルとした細胞内ストレスによる膵β細胞可塑性制御の解明2019
- Author(s)
  椎木幾久子、田部勝也、西村渉、幡中雅行、佐藤吉彦、駒津光久、増谷弘、谷澤幸生
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 健康成人の糖代謝の概日リズムとそのメカニズムの解明2019
- Author(s)
  藤本留理子、太田康晴、松村卓郎、田口昭彦、山本　薫、廣重俊典、秋山優、竹田孔明、明石真、谷澤幸生
- Organizer
  日本糖尿病学会中国四国地方会第57回総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 膵β細胞脱分化は糖尿病患者の膵β細胞不全に関連する2019
- Author(s)
  椎木幾久子、田部勝也、佐藤吉彦、駒津光久、谷澤幸生
- Organizer
  第69回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] New messengers in β-cell function：Physiology and pathophysiology　WFS1 and β-cell function2019
- Author(s)
  谷澤幸生、太田康晴、田部勝也、田口昭彦、椎木幾久子、秋山優、幡中雅行
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Islet cell plasticity and its significance in diabetes Pancreatic β cell plasticity as a mechanism of β cell failure caused by Wfs1 deficiency2019
- Author(s)
  田部勝也、椎木幾久子、幡中雅行、西村渉、増谷弘、谷澤幸生
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 筋・脂肪・肝のインスリン作用　出力系時計遺伝子 DBP, E4BP4を介した肝臓における脂質代謝制御機構2019
- Author(s)
  太田康晴、松村卓郎、田口昭彦、福田尚文、山本薫、柳井章江、秋山優、藤本留理子、神吉けい太、汐田剛史、水上洋一、篠田晃、谷澤幸生
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Wolfram症候群をモデルとした細胞内ストレスによる膵β細胞可塑性制御の解明2018
- Author(s)
  椎木幾久子，田部勝也，幡中雅行，西村渉，佐藤吉彦，駒津光久，増谷弘，谷澤幸生
- Organizer
  第61回日本糖尿病学会年次学術集会、東京
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] Metabolic Insufficiency Caused By Cellular Stresses Is Implicated in Beta-Cell Dedifferentiation in the Mouse Model of Wolfram Syndrome2018
- Author(s)
  Kikuko Amo-Shiinoki, Katsuya Tanabe, Masayuki Hatanaka, Hiroshi Masutani, Yukio Tanizawa
- Organizer
  78th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Circadian Dysregulation によるインスリン分泌不全と肝インスリン抵抗性2018
- Author(s)
  太田康晴，田口昭彦，松村卓郎，福田尚文，山本薫，柳井章江，秋山優，藤本留理子，神吉けい太，汐田剛史，水上洋一，篠田晃，谷澤幸生
- Organizer
  第61回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Metabolic insufficiency caused by cellular stresses is implicated to β cell dedifferentiation in the mouse model of Wolfram Syndrome2018
- Author(s)
  Amo-Shiinoki K, Tanabe K, Hatanaka M, Tanizawa Y
- Organizer
  第78回米国糖尿病学会、オーランド
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] 小胞体ストレスに対する膵β細胞保護におけるアドレノメデュリンの役割2018
- Author(s)
  秋山優、末富吏佐、太田康晴、松村卓郎、中林容子、近藤学、幡中雅行、田部勝也、谷澤幸生
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 肝における出力系時計遺伝子DBP/E4BP4によるエネルギー代謝調節2018
- Author(s)
  松村卓郎，太田康晴，田口昭彦，福田尚文，柳井章江，水上洋一，秋山優，末冨吏佐，山本薫，藤本留理子，神吉けい太，汐田剛史，篠田晃，谷澤幸生
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Metabolic insufficiency caused by cellular stresses is implicated to β cell dedifferentiation in the mouse model of Wolfram Syndrome2018
- Author(s)
  Amo-Shiinoki K, Tanabe K, Hatanaka M, Tanizawa Y
- Organizer
  第54回欧州糖尿病学会、ベルリン
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] Wolfram症候群をモデルとした細胞内ストレスによる膵β細胞可塑性制御の解明2018
- Author(s)
  椎木幾久子，田部勝也，幡中雅行，西村渉，佐藤吉彦，駒津光久，増谷弘，谷澤幸生
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 小胞体ストレス応答蛋白Wolfram Syndrome 1（WFS1）の肝インスリン抵抗性への役割2018
- Author(s)
  橋本麻美子，高俊弘，澤田正二郎，石垣泰，鈴木亨，近藤敬一，宇野健司，今井淳太，山田哲也，石原寿光，谷澤幸生，片桐秀樹
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] ヒトの糖尿病においてβ細胞脱分化はβ細胞不全に関連する2017
- Author(s)
  椎木幾久子、田部勝也、幡中雅行、近藤　学、西村　渉、木村徳宏、星井嘉信、池田栄二、水上浩哉、八木橋操六、佐藤吉彦、駒津光久、谷澤幸生
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Genetic Deficiency of TXNIP Prevents Diabetes Progression in the Mouse Model of Wolfram Syndrome.2017
- Author(s)
  Shinoki K., Tanabe K., Hatanaka M., Harano R., Masutani H., Tanizawa Y.
- Organizer
  77th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Wolfram症候群において膵β細胞脱分化は糖尿病の成因として重要である2017
- Author(s)
  田部勝也、椎木幾久子、幡中雅行、谷澤幸生
- Organizer
  第90回日本内分泌学会学術総会（京都）
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] Wolfram症候群のモデルマウスでは膵β細胞脱分化を来す2017
- Author(s)
  田部勝也、椎木幾久子、幡中雅行、谷澤幸生
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Circadian Dysregulation と肝インスリン抵抗性2017
- Author(s)
  太田康晴、松村卓郎、田口昭彦、福田尚文、秋山　優、藤本留理子、神吉けい太、汐田剛史、谷澤幸生
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 時計遺伝子DBP, E4BP4の機能異常と肝インスリン抵抗性2017
- Author(s)
  松村卓郎、太田康晴、田口昭彦、谷澤幸生、福田尚文、藤本留理子、山本　薫、神吉けい太、汐田剛史
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] DBPシグナルを介した時計遺伝子によるインスリン分泌調節機構2017
- Author(s)
  太田康晴、田口昭彦、松村卓郎、中林容子、秋山　優、藤本留理子、末冨吏佐、山本　薫、谷澤幸生
- Organizer
  第90回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 時計遺伝子DBP、E4BP4の異常は肝インスリン抵抗性を惹起する2017
- Author(s)
  松村卓郎、太田康晴、田口昭彦、山本　薫、福田尚文、藤本留理子、秋山優、神吉けい太、汐田剛史、谷澤幸生
- Organizer
  第29回分子糖尿病学シンポジウム
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Genetic deficiency of thioredoxin interacting protein (Txnip) prevents diabetes progression in the mouse model of Wolfram syndrome2017
- Author(s)
  Kikuko Amo-Shiinoki, Katsuya Tanabe, Masayuki Hatanaka, Yukio Tanizawa
- Organizer
  第77回米国糖尿病学会（San Diego, USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] 大規模臨床研究 J-BRABD Registry:第4回中間報告2017
- Author(s)
  山田祐一郎、中村二郎、植木浩二郎、谷澤幸生、綿田裕孝、下村伊一郎、西村理明、山崎　力、門脇　孝
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Wolfram症候群においてβ細胞脱分化は糖尿病の成因として重要である2017
- Author(s)
  田部勝也、椎木幾久子、幡中雅行、谷澤幸生
- Organizer
  第32回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] ER and oxidative stresses induce and Txnip knock-out prevents β-cell dedifferentiation and failure in Wolfram syndrome2017
- Author(s)
  Yukio Tanizawa, Kikuko Amo-Shiinoki, Katsuya Tanabe, Masayuki Hatanaka, Risa Harano, Hiroshi Masutani
- Organizer
  International Diabetes Federation Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Wolfram症候群のモデルマウスでは膵β細胞脱分化を来す2017
- Author(s)
  田部勝也、椎木幾久子、幡中雅行、谷澤幸生
- Organizer
  第９０回日本内分泌学会学術集会
- Place of Presentation
  京都市（京都市勧業館みやこめっせ）
- Year and Date
  2017-04-20
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 過食肥満動物Agoutiマウスは高脂肪食負荷により非アルコール性脂肪肝炎(NASH)を発症する2017
- Author(s)
  香川正太、田部勝也、長島史裕、谷澤幸生
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] DBP signal has pivotal role in the circadian regulation of liver metabolism2017
- Author(s)
  Matsumura T, Ohta Y, Taguchi A, Fukuda N, Akiyama M, Fujimoto R, Tanizawa Y
- Organizer
  International Diabetes Federation Congress 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] DBPシグナルを介した時計遺伝子によるインスリン分泌調節機構2017
- Author(s)
  太田康晴、田口昭彦、松村卓郎、中林容子、秋山優、藤本留理子、末冨吏沙、山本薫、谷澤幸生
- Organizer
  第９０回日本内分泌学会学術集会
- Place of Presentation
  京都市（京都市勧業館みやこめっせ）
- Year and Date
  2017-04-20
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] ヒトの糖尿病においてβ細胞脱分化はβ細胞不全に関連する2017
- Author(s)
  椎木幾久子、田部勝也、幡中雅行、近藤学、西村渉、木村徳宏、星井嘉信、池田栄二、水上浩哉、八木橋操六、佐藤吉彦、駒津光久、谷澤幸生
- Organizer
  第60回日本糖尿病学会学術総会（名古屋）
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] β cell dedifferentiation plays a central role in β cell failure in a model of Wolfram syndrome2016
- Author(s)
  Katsuya Tanabe, Kikuko Shiinoki, Masayuki Hatanaka, Yukio Tanizawa
- Organizer
  第59回日本糖尿病学会年次学術総会
- Place of Presentation
  京都国際会議場（京都府、京都市）
- Year and Date
  2016-05-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] 膵β細胞におけるＤＢＰシグナルはfirst meal摂取時の鋭敏なインスリン分泌にとって重要である2016
- Author(s)
  松村卓郎、太田康晴、田口昭彦、中林容子、秋山　優、末冨吏佐、山本　薫。谷澤幸生
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  京都市（国立京都国際会館）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] β cell dedifferentiation plays a central role in β cell failure in a model of Wolfram syndrom2016
- Author(s)
  田部勝也、椎木幾久子、幡中雅行、谷澤幸生
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  京都市（国立京都国際会館）
- Year and Date
  2016-05-19
- Invited
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 膵島炎症に対するn-3ＰＵＦＡの抑制効果とその発現機構の解明2016
- Author(s)
  椎木幾久子、田部勝也、谷澤幸生
- Organizer
  第19回日本病態栄養学会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 肝細胞特異的Ｅ4ＢＰ4過剰発現マウスを用いた時計遺伝子を介する糖代謝調節機構の解明2016
- Author(s)
  松村卓郎、太田康晴、田口昭彦、福田尚文、秋山　優、末冨吏佐、山本　薫、谷澤幸生、神吉けい太、汐田剛史
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京都（東京ファッションタウン）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Wfs1-Defiency Causes Beta-Cell Dedifferentiation Associated with Enhanced ER Stress and Oxidative Stress, Independently of Hyperglycemia.2016
- Author(s)
  Shinoki K., Tanabe K., Hatanaka M., Tanizawa Y.
- Organizer
  7th AASD Scientific Meeting and Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-11-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] β cell dedifferentiation plays a central role in β cell failure in a model of Wolfram syndrome2016
- Author(s)
  Kikuko Shiinoki, Katsuya Tanabe, Masayuki Hatanaka, Yukio Tanizawa
- Organizer
  第76回米国糖尿病学会
- Place of Presentation
  New Orleans (USA)
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09752
[Presentation] Beta-cell Dedifferentiation Plays a Central Role in Beta-Cell Failure in a Model of Wolfram Syndrome.2016
- Author(s)
  Shinoki K., Tanabe K., Hatanaka M., Kondo M., Tanizawa Y.
- Organizer
  76th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Hong Kong, China
- Year and Date
  2016-06-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Clock gene dysreguration induced by chronic endoplasmic reticulum stress disrupts　β-cell function.2016
- Author(s)
  Ohta Y., Tanizawa Y.
- Organizer
  The 11TH IDF-WPR Congress ＆ 8TH AASD Scientific Meeting.
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] SNARE調節因子DOC2bによる個体糖代謝調節2015
- Author(s)
  野見山隆太、江本政広、福田尚文、松井久未子、坂根亜由子、三好　淳、佐々木卓也、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  グランプラス　セント・バレンタイン、下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Wfs1-deficiency causes beta-cell dedifferentiation associated with enhanced ER stress and oxidative stress, independently of hyperglycemia.2015
- Author(s)
  Kikuko Amo-Shinoki, Katsuya Tanabe, Masayuki Hatanaka, Yukio Tanizawa
- Organizer
  7th AASD Scientific Meeting and Annual Scientific Meeting of the Hong Kong Society of Endocrinology, Metabolism and Reproduction
- Place of Presentation
  Hong Kong Convention and Exhibition Centre, Hong Kong, Special Administrative Region of the People’s Republic of China
- Year and Date
  2015-11-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] DBPシグナルはグルコース応答性のインスリン分泌とりわけfirst meal摂取時のインスリン分泌にとって重要である2015
- Author(s)
  松村卓郎、太田康晴、田口昭彦、中林容子、秋山　優、末冨吏佐、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  シーモールホール、下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] WFS1欠損膵島における膵β細胞脱分化機構の解析2015
- Author(s)
  椎木幾久子、田部勝也、幡中雅行、永尾優子、太田康晴、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  グランプラス　セント・バレンタイン、下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Wfs1 Deficiency Causes Beta-Cell Dedifferentiation Associated with Enhanced ER Stress and Oxidative Stress, Independently of Hyperglycemia.2015
- Author(s)
  Shinoki K., Tanabe K., Hatanaka M., Ohta Y., Tanizawa Y.
- Organizer
  75th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Boston Convention and Exhibition Center, Boston, MA, USA.
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] SNARE調節因子DOC2bによる個体糖代謝調節2015
- Author(s)
  野見山隆太、江本政広、福田尚文、松井久未子、坂根亜由子、三好　淳、佐々木卓也、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  グランプラス　セント・バレンタイン(山口県下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461356
[Presentation] Wfs1欠損マウスにおける膵β細胞脱分化とその意義の解明2015
- Author(s)
  椎木幾久子、田部勝也、幡中雅行、香川正太、秋山優、谷澤幸生
- Organizer
  第27回分子糖尿病シンポジウム
- Place of Presentation
  丸ビルホール&コンファレンススクエア（東京都）
- Year and Date
  2015-12-05
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] DBP/E4BP4 plays a pivotal role in circadian regulation of β-cell function.2015
- Author(s)
  Ohta Y., Taguchi A., Akiyama M., Nakabayashi H., Suetomi R., Yanai A., Shinoda K., Tanizawa Y.
- Organizer
  16th Servier-IGIS(International Group on Insulin Secretion) symposium
- Place of Presentation
  The Royal Riviera Hotel, St. Jean Cap Ferrat, France
- Year and Date
  2015-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Adrenomedullin Has a Cytoprotective Role in Pancreatic β-Cells Against ER Stress.2015
- Author(s)
  Akiyama M., Suetomi R., Ohta Y., Nakabayashi H., Kondo M., Tanabe K., Tanizawa Y.
- Organizer
  75th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Boston Convention and Exhibition Center, Boston, MA, USA.
- Year and Date
  2015-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] Gsk-3による小胞体ストレス応答制御と膵β細胞アポトーシス誘導における意義とその解明2015
- Author(s)
  永尾優子、田部勝也、椎木幾久子、幡中雅行、太田康晴、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  シーモールホール、下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 膵ラ氏島におけるアドレノメデュリンは小胞体ストレスに対して自己防御的な作用をもつ2015
- Author(s)
  末冨吏佐、秋山　優、太田康晴、中林容子、近藤　学、田部勝也、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  グランプラス　セント・バレンタイン、下関市
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 患者から学ぶ膵β細胞研究－physician scientistのゆめ－2015
- Author(s)
  谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  海峡メッセ下関、下関市
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-15H04849
[Presentation] 時計遺伝子DBP/E4BP4 による膵 β 細胞機能調節2014
- Author(s)
  田口昭彦,太田康晴,山本将義,薄陽祐,中林容子,谷澤幸生
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵 β 細胞特異的E4BP4 過剰発現マウスを用いた時計遺伝子を介する新たなインスリン分泌調節機構の解明2014
- Author(s)
  太田康晴,田口昭彦,中林容子,秋山優,末冨吏佐,谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵β 細胞でのアドデノメデュリンシグナルは小胞体ストレスに対して保護作用を示す2014
- Author(s)
  末冨吏佐,秋山優,太田康晴,中林容子,近藤学,幡中雅行,谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  第 57 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Role of GSK3 in the development of β-cell failure2014
- Author(s)
  Tanabe K., Nagao Y., Shiinoki-Amo K., Ma Permutt, Tanizawa Y
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] GLUT4 調節因子DOC2b は aPKC により調節され個体糖恒常性を維持する2014
- Author(s)
  野見山隆太,江本政広,福田尚文,松井久未子,坂根亜由子,三好淳,佐々木卓也,谷澤幸生
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 全エキゾーム解析による Wolfram 症候群の新たな原因遺伝子同定の試み2014
- Author(s)
  田口昭彦,田部勝也,松永仁恵,太田康晴,細道一善,井ノ上逸朗,谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵島炎症にたいする n-3PUFA の抑制効果とその発現機構の解明2014
- Author(s)
  椎木幾久子,田部勝也,永尾優子,秋山優,太田康晴,谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Rac1 and its novel effecter regulate insulin stimulated glucose transport2013
- Author(s)
  Emoto M., Fukuda N., Nomiyama R., Yamada K., Tanizawa Y
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル、熊本市
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] SNARE調節因子Doc2bの糖恒常性維持における役割2013
- Author(s)
  野見山隆太江本政広　福田尚文　松井久未子　谷澤幸生　坂根亜由子　佐々木卓也三好淳
- Organizer
  第63回日本体質医学会総会
- Place of Presentation
  久留米市（久留米大学筑水会館）
- Data Source
  KAKENHI-PROJECT-25461356
[Presentation] SCF^<βTrC> and GSK3-mediated degr -adation of ATF4 is a pro-apoptotic mechanism in pancreatic beta cell under ER stress2013
- Author(s)
  Tanabe K., Nagao Y., Tanizawa Y
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  メルパルク熊本
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Molecular pathophysiology of beta-cell failure in diabetes mellitus.2013
- Author(s)
  Tanizawa Y
- Organizer
  The 26th Spring Congress of Korean Diabetes Association / The 1st Korea-Japan Diabetes Forum
- Place of Presentation
  ICC Jeju, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-Controlled Output Gene Dbp is a Regulator of Arnt/Hif-1β Gene Expression in Pancreatic Islet β-Cells.2013
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y., Tanizawa Y.
- Organizer
  73th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Chicago, IL, USA.
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1β gene expression in pancreatic islet β-cells2013
- Author(s)
  Ohta Y., Nakabayashi H., Tanabe K., Tanizawa Y
- Organizer
  Keystone Symposia Molecular Clockworks and the Regulation of Cardio-Metabolic Function
- Place of Presentation
  Snowbird Resort - Snowbird, Utah USA
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] GLUT4 vesicle fusion regulator DOC2b is required for systemic glucose homeostasis.2013
- Author(s)
  野見山隆太江本政広　福田尚文　松井久未子　谷澤幸生　坂根亜由子　佐々木卓也三好淳
- Organizer
  International Diabetes Federation 2013
- Place of Presentation
  オーストラリア（メルボルン）
- Data Source
  KAKENHI-PROJECT-25461356
[Presentation] SNARE関連蛋白質Doc2bの糖代謝への役割2013
- Author(s)
  野見山隆太江本政広　福田尚文　松井久未子　谷澤幸生　坂根亜由子　佐々木卓也三好淳
- Organizer
  第56回糖尿病学会年次学術集会
- Place of Presentation
  熊本市（ホテル日航熊本）
- Data Source
  KAKENHI-PROJECT-25461356
[Presentation] Clock-controlled output gene Dbp is a regulator of Arnt/Hif- 1β gene expression in pancreatic islet β-cells2013
- Author(s)
  Tanizawa Y., Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y.
- Organizer
  EASD ISLET STUDY GROUP ANNUAL MEETING 2013 (Beta-cell Regeneration and Genome Regulation)
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Both quantitative and qualitative abnormalities of beta-cells in patients with Wolfram syndrome.2013
- Author(s)
  Tanizawa Y
- Organizer
  Beta Cell Workshop 2013
- Place of Presentation
  Kyoto International Conference Center, Kyoto.
- Invited
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Gsk-3 modulates ER stress-induced apoptosis by regulating ATF4 protein stability in pancreatic β-cell.2013
- Author(s)
  Nagao Y., Tanabe K., Hatanaka M., Nakabayashi H., Ohta Y.,Emoto M., Tanizawa Y.
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル、熊本市
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] SNARE関連蛋白質ＤＯＣ2bの糖代謝への役割2013
- Author(s)
  野見山隆太、江本政広、福田尚文、松井久未子、坂根亜由子、三好　淳、佐々木卓也、谷澤幸生
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市民会館、熊本市
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] SCFβTγCP and GSK3-mediated degradation of ATF4 is a pro-apoptotic mechanism in pancreatic beta cell under ER stress.2013
- Author(s)
  Tanabe K., Nagao Y., Tanizawa Y.
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  メルパルク熊本、熊本市
- Invited
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Both quantitative and qualitative abnormalities of beta-cells in patients with Wolfram syndrome.2013
- Author(s)
  Yukio Tanizawa
- Organizer
  Beta Cell Workshop 2013 Kyoto
- Place of Presentation
  国立京都国際会館　（京都）
- Invited
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] SNARE 関連蛋白質DOC2b の糖代謝への役割2013
- Author(s)
  野見山隆太,江本政広,福田尚文,松井久未子,坂根亜由子,三好淳,佐々木卓也,谷澤幸生
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本市民会館
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-Controlled Output Gene Dbp is a Regulator of Arnt/Hif-1β Gene Expression in Pancreatic Islet β-Cells2013
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y., Tanizawa Y
- Organizer
  73th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] DOC2b regulates glucose homeostasis through insulin mediated aPKC activation and GLUT4 vesicle fusion.2013
- Author(s)
  野見山隆太江本政広　福田尚文　松井久未子　谷澤幸生　坂根亜由子　佐々木卓也三好淳
- Organizer
  2013年ICDM＆第5回AASD
- Place of Presentation
  韓国（ソウル）
- Data Source
  KAKENHI-PROJECT-25461356
[Presentation] Rac1 and its novel effector regulate insulin stimulated glucose transport2013
- Author(s)
  Emoto M., Fukuda N., Nomiyama R., Yamada K., Tanizawa Y
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] aPKCはSNARE調節因子DOC2bの機能発現に必要である2013
- Author(s)
  野見山隆太江本政広　福田尚文　松井久未子　谷澤幸生
- Organizer
  第51回日本糖尿病学会中国四国地方会
- Place of Presentation
  岡山市（岡山コンベンションセンター）
- Data Source
  KAKENHI-PROJECT-25461356
[Presentation] Gsk-3 modulates ER stress-induced apoptosis by regulating ATF4 protein stability in pancreatic β-cell2013
- Author(s)
  Nagao Y., Tanabe K., Hatanaka M., Nakabayashi H., Ohta Y., Emoto M., Tanizawa Y
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Molecular pathophysiol -ogy of beta-cell failure in diabetes mellitus2013
- Author(s)
  Tanizawa Y
- Organizer
  The 26th Spring Congress of Korean Diabetes Association / The 1st Korea-Japan Diabetes Forum
- Place of Presentation
  ICC Jeju, Korea
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Molecular pathophysiology of beta-cell failure in diabetes mellitus.2013
- Author(s)
  Yukio Tanizawa
- Organizer
  The 26th Spring Congress of Korean Diabetes Association / The 1st Korea-Japan Diabetes Forum
- Place of Presentation
  Jeju, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1β; gene expression in pancreatic islet β-cells.2013
- Author(s)
  Ohta Y., Nakabayashi H., Tanabe K., Tanizawa Y.
- Organizer
  Keystone Symposia Molecular Clockworks and the Regulation of Cardio-Metabolic Function
- Place of Presentation
  Snowbird, Utah USA
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Both quantitative and qualitative abnormalities of beta-cells in patients with Wolfram syndrome2013
- Author(s)
  Tanizawa Y
- Organizer
  Beta Cell Workshop 2013 Kyoto (Abstract 3P)
- Place of Presentation
  Kyoto International Conference Center, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵β細胞において時計遺伝子DBPとE4BP4はARNTの発現を抑制する2013
- Author(s)
  中林容子、太田康晴、山本将義、薄　陽祐、谷澤幸生
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル、熊本市
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵 β 細胞において時計遺伝子 DBP と E4BP4 は ARNT の発現を抑制する2013
- Author(s)
  中林容子,太田康晴,山本将義,薄陽祐,谷澤幸生
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵β細胞特異的E4BP4過剰発現マウスを用いたDBP及びE4BP4の膵β細胞機能における役割の解明2013
- Author(s)
  太田康晴、中林容子、近藤　学、谷澤幸生
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル、熊本市
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1βgene expression in pancreatic islet β-cells.2013
- Author(s)
  Tanizawa Y., Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y.
- Organizer
  EASD ISLET STUDY GROUP ANNUAL MEETING 2013
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵 β 細胞特異的 E4BP4 過剰発現マウスを用いた DBP 及び E4BP4 の膵 β細胞機能における役割の解明2013
- Author(s)
  太田康晴,中林容子,近藤学,谷澤幸生
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本ホテルキャッスル
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] t-SNARE であるSNAP29 は GULT4 小胞のインスリン感受性コンパートメントを形成し維持する2012
- Author(s)
  松井久未子,江本政広,福田尚文,野見山隆太,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] セリン・スレオニンキナーゼGSK-3 は ATF4 を抑制的に調節する2012
- Author(s)
  永尾優子,田部勝也,幡中雅行,中林容子,近藤学,太田康晴,江本政広,谷澤幸生
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Role of Gsk-3β βin the Development of β-Cell Failure2012
- Author(s)
  Tanabe K., Tanizawa Y
- Organizer
  The 4th Scientific Meeting of the Asian Association for the Study of Diabetes, 9th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  Kyoto International Conference Center, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 糖尿病におけるβ細胞不全の分子機構2012
- Author(s)
  谷澤幸生
- Organizer
  第６２回日本体質医学会総会
- Place of Presentation
  大阪国際会議場（大阪）
- Invited
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] シンポジウム7小胞体ストレスと内分泌代謝疾患 : Glycogen synthase kinase-3(Gsk-3)2012
- Author(s)
  田部勝也,谷澤幸生
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 断面調査に基づく Wolfram 症候群の実態解明2012
- Author(s)
  松永仁恵,田部勝也,太田康晴,奥屋茂,和田安彦,中尾雄三,山田祐一郎,雨宮伸,杉原茂孝,岡芳知,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] GSK-3 enhances ER stress-induces apoptosis by regulation of ATF4 protein stability in pancreatic β-cells2012
- Author(s)
  田部勝也,永尾優子,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] GSK3-SCF^<βTrCP> Modulates ER Stress-Induced Apoptosis by Targeting ATF4 for Ubiquitination and Degradation in Pancreatic β-Cell2012
- Author(s)
  Nagao Y., Tanabe K., Hatanaka M., Emoto M., Tanizawa Y.
- Organizer
  The 4 th Scientific Meeting of the Asian Association for the Study of Diabetes, 9 th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  Kyoto International Conference Center, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Adrenomedullin is Induced by ER Stress and Protects β-Cells as Endogenous Antiapoptotic Substance in Islets2012
- Author(s)
  Ohta Y., Nakabayashi H., Kondo M., Hatanaka M., Tanabe K., Tanizawa Y.
- Organizer
  The 4th Scientific Meeting of the Asian Association for the Study of Diabetes, 9th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  Kyoto International Conference Center, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 糖尿病における β 細胞不全の分子機構2012
- Author(s)
  谷澤幸生
- Organizer
  第62回日本体質医学会総会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] A SNARE Protein p34 Regulates the Intracellular Sequestration of GLUT4 Vesicles in Adipocytes2012
- Author(s)
  Matsui K., Emoto M., Fukuda N., Nomiyama R., Tanizawa Y
- Organizer
  72th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Philadelphia, Pennsyl -vania, USA
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] SNARE関連蛋白 DOC2b による糖代謝調節2012
- Author(s)
  野見山隆太,江本政広,福田尚文,松井久未子,佐々木卓也,谷澤幸生
- Organizer
  第24回分子糖尿病学シンポジウム
- Place of Presentation
  品川インターシティ
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] シンポジウム7小胞体ストレスと内分泌代謝疾患:Glycogen synthase kinase-3 (Gsk-3)2012
- Author(s)
  田部勝也、谷澤幸生
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋国際会議場名古屋市(招待講演)
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] WFS1 遺伝子と糖尿病2012
- Author(s)
  太田康晴,田部勝也,松永仁恵,近藤学,中林容子,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] WFS1 Protein Regulates Insulin Granule Exocytosis via Maintenance of Intragranular Acidification and Modulation of the SNARE Proteins2012
- Author(s)
  Kondo M., Hatanaka M., Tanabe K, Ohta Y., Tanizawa Y
- Organizer
  72th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Philadelphia, Pennsyl -vania, USA
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] SNARE 関連蛋白DOC2b による糖代謝調節2012
- Author(s)
  福田尚文,江本政広,野見山隆太,松井久未子,坂根亜由子,三好淳,佐々木卓也,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 小胞体ストレス応答調節におけるセリン・スレオニンキナーゼ GSK-3の役割2012
- Author(s)
  永尾優子,田部勝也,幡中雅行,中林容子,近藤学,太田康晴,江本政広,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] W fs 1 欠損マウスにおけるインスリン分泌動態の解析2012
- Author(s)
  近藤学,幡中雅行,田部勝也,太田康晴,谷澤幸生,岡芳知
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵 β 細胞において時計遺伝子 E4bp4 と Dbp は Arnt の発現を制御する2012
- Author(s)
  中林容子,太田康晴,山本将義,薄陽祐,田部勝也,近藤学,幡中雅行,永尾陽子,谷澤幸生
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  第 55 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Coock-Controlled Output Gene Dbp is a Regulator of Arnt/Hif-1βGene Expression in Pancreatic Islet β-Cells2012
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Tanabe K., Kondo M., Hatanaka M., Nagao Y., Tanizawa Y.
- Organizer
  The 4th Scientific Meeting of the Asian Association for the Study of Diabetes, 9th International Diabetes Federation Western Pacific Region Congress
- Place of Presentation
  Kyoto International Conference Center, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] セリン・スレオニンキナーゼ GSK-3 はATF4 を抑制的に調節する2011
- Author(s)
  中林容子,田部勝也,太田康晴,幡中雅行,近藤学,江本政広,谷澤幸生
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Charac -terization of visual impairment in a Wfs1 mouse model of Wolfram syndrome2011
- Author(s)
  Hamel CP., Cribaillet CD., Lenaers G., Tanizawa Y., Wersinger DB
- Organizer
  ARVO Annual Meeting
- Place of Presentation
  Fort Lauderdale
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] The cross sectional analysis on genetic and clinical features of Japanese patient with Wolfram syndrome2011
- Author(s)
  Matsunaga K., Tanabe K., Ohta Y., Okuya S., Tanizawa Y
- Organizer
  The 3th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Pioglitazone induces islet adreno -medullin expression and attenuates beta-cell ER stress2011
- Author(s)
  Ohta Y., Kondo M., Hatanaka M., Tanabe K., Yamamoto M., Nakabayashi H., Tanizawa Y
- Organizer
  The 3th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] ピオグリタゾンによる膵ラ氏島でのアドレノメデュリンの発現誘導と膵 β細胞保護作用に関する検討2011
- Author(s)
  田部勝也,中林容子,山本将義,谷澤幸生
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Roles of Wolfram Syndrome 1 Gene Product (WFS1) on Beta Cell Function and its Adaptation to increased Insulin Demand2011
- Author(s)
  Tanabe K.,Tanizawa Y
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] GLUT4小胞は CLIP170 を介して微小管からアクチンへ移動する2011
- Author(s)
  江本政広,松井久未子,河村由紀江,福田尚文,山田恭子,谷澤幸生
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Genetic and acquired factors determining natural history of type 2 diabetes mellitus2011
- Author(s)
  Tanizawa Y
- Organizer
  The 3th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Syntaxin 6 結合蛋 p34 は脂肪細胞におけるインスリン依存性糖輸送を制御する2011
- Author(s)
  松井久未子,福田尚文,江本政広,谷澤幸生
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Wolfram 症候群の実態調査2011
- Author(s)
  松永仁恵,田部勝也,太田康晴,奥屋茂,和田安彦,山田祐一郎,雨宮伸,杉原茂孝,岡芳知,谷澤幸生
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Genetic and acquired factors determining natural history of type 2 diabetes mellitus2011
- Author(s)
  Tanizawa Y, 他
- Organizer
  The 3rd Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Beijing, China(招待講演)
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] The Cross Sectional Analysis on Genetic and Clinical Features of Japanese Patients2011
- Author(s)
  Matsunaga K., Tanabe K., Ohta Y., Okuya S., Tanizawa Y
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  Urayasu, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Pioglitazone Prevents ER Stress-induced Beta-cell Death via Adrenomedullin Expression2011
- Author(s)
  Ohta Y., Nakabayashi H., Tanabe K., Kondo M., Tanizawa Y
- Organizer
  The 16th Japan-Korea Symposium on Diabetes Mellitus
- Place of Presentation
  Urayasu, Japan
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Wolfram症候群の実態調査2010
- Author(s)
  田部勝也、太田康晴、奥屋茂、和田安彦、山田祐一郎、岡芳知、谷澤幸生
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] GLP-1アナログExendin-4はWfs1欠損マウスの耐糖能を改善する2010
- Author(s)
  近藤学、太田康晴、幡中雅行、田部勝也、谷澤幸生
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Beta cell failure in type 2 diabetes.2010
- Author(s)
  Tanizawa Y
- Organizer
  Asian Diabetes Forum in Tokushima 2010
- Place of Presentation
  Tokushima, Japan(Tokushima University Hospital)
- Year and Date
  2010-08-11
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] 糖尿病における細胞障害メカニズム:Wolfram症候群におけるβ細胞障害-ER stress and beyond-2010
- Author(s)
  谷澤幸生
- Organizer
  第25回日本糖尿病合併症学会
- Place of Presentation
  大津市びわ湖ホール
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] ピオグリタゾンによる膵ラ氏島でのアドレノメデュリンの発現誘導と膵β細胞保護作用2010
- Author(s)
  太田康晴、近藤学、幡中雅行、田部勝也、山本将義、中林容子、谷澤幸生
- Organizer
  第22回分子糖尿病学シンポジウム
- Place of Presentation
  東京都東京コンファレンスセンター
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] 糖尿病における細胞障害メカニズム:Wolfram症候群におけるβ細胞障害-ER stress and beyond-2010
- Author(s)
  谷澤幸生
- Organizer
  第25回日本糖尿病合併症学会
- Place of Presentation
  大津市(びわ湖ホール)
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Wolfram syndrome 1 gene (wfs1) product localizes to insulin granule in mouse pancreatic beta cells.2010
- Author(s)
  Hatanaka M., Tanabe K., Ohta Y., Yanai A., Akiyama M., Kondo M., Shinoda K., Oka Y., Tanizawa Y.
- Organizer
  The 2^<nd> Scientific Meeting of the Asian Association for the Stuey of Diabetes, (Abstract 60p)
- Place of Presentation
  岡山市岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] ピオグリタゾンのもつ膵β細胞の保護作用における膵ラ氏島でのアドレノメデュリンの発現意義2010
- Author(s)
  太田康晴、近藤学、幡中雅行、田部勝也、中林容子、谷澤幸生
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Long-term administration of exendin-4 improves glucose tolerance in Wfs1-deficient mice.2010
- Author(s)
  Kondo M, Ohta Y, Hatanaka M, Tanabe T, Tanizawa Y
- Organizer
  The 11^<th> Symposium on Molecular Diabetology in Asia
- Place of Presentation
  Splendor Kaohsiung Hotel, Kaohsiung Taipei, TAIWAN.
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Glycogen ynthase Kinase 3 Promotes ATF4 Protein Degradation inPancreatic Beta Cell During ER Stress.2010
- Author(s)
  Nakabayashi H., Tanabe K., Oka Y., Hatanaka M., Kondo M., Emoto M., Tanizawa Y.
- Organizer
  8^<th> International Diabetes Federation Western Pacific Region Congress (Abstract 159P)
- Place of Presentation
  Nurimaru APEC House, Busan, Korea.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Beta cell failure in type 2 diabetes.2010
- Author(s)
  谷澤幸生
- Organizer
  Asian Diabetes Forum in Tokushima 2010
- Place of Presentation
  徳島市徳島大学病院
- Year and Date
  2010-08-11
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] The roles of glycogen synthase kinase-3 β in the regulation of β-cell mass in insulin resistant diabetes models2010
- Author(s)
  田部勝也、MA Permutt、谷澤幸生
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Chronic Administration of Exendin-4 Improves Glucose Tolerance and Insulin Secretion.2010
- Author(s)
  Kondo M., Ohta Y., Hatanaka M., Tanabe K., Tanizawa Y.
- Organizer
  8^<th> International Diabetes Federation Western Pacific Region Congress (Abstract 173P)
- Place of Presentation
  Nurimaru APEC House, Busan, Korea.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] 膵β細胞量調節におけるセリン・スレオニンキナーゼGSK-3βの役割2010
- Author(s)
  田部勝也、幡中雅行、太田康晴、谷澤幸生
- Organizer
  日本糖尿病学会中国四国地方会第48回総会
- Place of Presentation
  松山市愛媛県県民文化会館
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Wolfram Syndrome 1 Gene (wfs1) Product Localizes to Secretory Granule and Contributes to Maintenance of Granular Acidification in Pancreatic Beta Cells.2010
- Author(s)
  Hatanaka M., Tanabe K., Ohta Y., Yanai A., Akiyama M., Kondo M., Shinoda K., Oka Y.,Tanizawa Y.
- Organizer
  70th Annual Meeting and Scientific Sessions of the American Diabetes Association (Abstract A76P)
- Place of Presentation
  Orange Country Convention Center, Orlando, FL, USA.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] WFS1蛋白はインスリン分泌顆粒に局在し、顆粒内酸性化能維持に重要である2009
- Author(s)
  幡中雅行、田部勝也、太田康晴、柳井章江、秋山優、近藤学、篠田晃、岡芳知、谷澤幸生
- Organizer
  第21回分子糖尿病学シンポジウム
- Place of Presentation
  和歌山市和歌山東急イン
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] WFS1蛋白はインスリン分泌顆粒に局在する2009
- Author(s)
  幡中雅行、太田康晴、柳井章江、田部勝也、秋山優、近藤学、篠田晃、谷澤幸生
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋市群馬県民会館
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] WFS1蛋白はインスリン分泌顆粒に局在する2009
- Author(s)
  幡中雅行、太田康晴、柳井章江、田部勝也、秋山優、近藤学、鶴政俊、篠田晃、谷澤幸生
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪大阪国際会議場
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] GSK-3βは膵β細胞においてインスリン情報伝達を抑制的に制御する2009
- Author(s)
  部勝也、幡中雅行、近藤学、太田康晴、Mashall Alan Permutt 谷澤幸生
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪大阪国際会議場
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] GSK-3βの欠損は、IRS2欠損マウスにおける糖尿病を改善させる2009
- Author(s)
  田部勝也、マーシャル・アランパーマット、谷澤幸生
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋市群馬県民会館
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Wolfram Syndrome 1 Gene (wfs1) Product Localizes to Secretory Granule and Determines Acidification of Granule in Pancreatic Beta Cells.2009
- Author(s)
  Hatanaka M, Tanabe K, Ohta Y, Yanai A, Akiyama M, Kondo M, Shinoda, K Oka Y, Tanizawa Y
- Organizer
  The 15^h Korea-Japan Symposium onDiabetes Mellitus, (Abstract 167p)
- Place of Presentation
  International Convention Center Jeju, Jeju, Korea.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Increased Insulin Demand Causes While Pioglitazone Prevents Pancreatic β-Cell Apoptosis in Wfs1 Knock-out Mice.2008
- Author(s)
  Akiyama M, Ueda K, Hatanaka M, Uehara Y, Yanai A, Tsuru M, Ohta Y, Miyazaki M, Saeki S, Saito T, Shinoda K, Oka Y, Tanizawa Y
- Organizer
  Keystone Symposia on Molecular and Cellular Biology, Islet Beta Cell Biology
- Place of Presentation
  Snowbird Resort, Snowbird, UT, USA
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] インスリンによる糖取り込み促進機構とインスリン抵抗性が加速するβ細胞死2008
- Author(s)
  谷澤幸生
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Wolfram Syndrome : Mechanism of Genetically Programmed β -cell Death.2008
- Author(s)
  Tanizawa Y
- Organizer
  The 10^<th> Symposium on Molecular Diabetology in Asia, and The 1^<st> Sun Yat-Sen Diabetes Forum
- Place of Presentation
  Guangzhou, CHINA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390103
[Presentation] Genetic Deficiency of Glycogen Synthase Kinase-3beta Corrects Diabetes in Irs2 knockout mice by preserving beta cell mass.2008
- Author(s)
  Tanabe K, Cras-Meneur C, White MF, Bernal-Mizrachi E, Woodgett JR, Permutt MA, Tanizawa Y
- Organizer
  The 1^<st> Insulin Resistance in Metabolic Disease Forum
- Place of Presentation
  大阪市ホテル阪急インターナショナル
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Increased Insulin Demand Causes While Pioglitazone Prevents Pancreatic B-Cell Apoptosis in Wfsl Knockout Mice.2008
- Author(s)
  Yukio Tanizawa, et. al.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology, Islet Beta Cell Biology
- Place of Presentation
  Snowbird,UT,USA
- Data Source
  KAKENHI-PROJECT-18390103
[Presentation] Wolfram Syndrome : Mechanism of Genetically Programmed β-cell Death.2008
- Author(s)
  谷澤幸生
- Organizer
  The 10^<th> Symposium on Molecular Diabetology in Asia, The 1^<st> Sun Yat-Sen Diabetes Forum (Abstract 36p) Educational Lecture
- Place of Presentation
  HJGRAND HOTEL, Guangzhou, CHINA.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Wolfram Syndrome : Mechanism of Genetically Programmedβ-cell Death.2008
- Author(s)
  Tanizawa Y
- Organizer
  The 10^<th> Symposium on Molecular Diabetology in Asia
- Place of Presentation
  Guangzhou, CHINA.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] 膵ラ氏島において、ETS転写因子であるPet-1はNeurogenin-Nkx転写カスケードの下流に位置し、インスリンプロモーターに結合する2008
- Author(s)
  太田康晴、Yasuhiro Kosaka, Nicole Neubauer, Rosa Gasa, Evan Deneris, Michael German, 谷澤幸生
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] GSK-3βの欠損は、IRS2欠損マウスにおける糖尿病を改善させる2008
- Author(s)
  田部勝也、James R.Woodgett、M.Alan Permutt、谷澤幸生
- Organizer
  第20回分子糖尿病学シンポジウム
- Place of Presentation
  東京東京カンファレンスセンター品川
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] Increased Insulin Demand Causes While Pioglitazone Prevents Pancreatic β-Cell Apoptosis in Wfs1 Knock-out Mice.2008
- Author(s)
  Tanizawa Y, et al.
- Organizer
  Keystone Symposia on Molecular and Cellular Biology, Islet Beta Cell Biology
- Place of Presentation
  Snowbird, UT, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390103
[Presentation] Genetic Deficiency of Glycogen Synthase Kinase-3beta Corrects Diabetes in Irs2 Knockout Mice by Preserving Beta Cell Mass.2008
- Author(s)
  Tanabe K, Cras-Meneur C, White MF, Bernal-Mizrachi E, Woodgett JP, Permutt MA, Tanizawa Y
- Organizer
  Asia Islet Biology & Incretin Symposium (AIBIS)
- Place of Presentation
  International Multi-Conference, Incheon, Korea.
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] インスリン分泌機構におけるDOC 2bの役割2008
- Author(s)
  宮崎睦子、江本政広、福田尚文、田口昭彦、宮本幸子、松原淳、奥屋茂、谷澤幸生
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-20390093
[Presentation] インスリン需要増大時の膵β細胞小胞体ストレスと細胞死-wfs1欠損マウスをモデルとした検討-2007
- Author(s)
  谷澤幸生, 他
- Organizer
  第50回日本糖尿病学会年次学術集会
- Place of Presentation
  仙台市
- Year and Date
  2007-05-24
- Data Source
  KAKENHI-PROJECT-18390103
[Presentation] Distribution of wolframin, the Wfs1(Wolfram syndrome 1) gene product, in the normal mouse visual system.2006
- Author(s)
  Kawano J, Tanizawa Y, Shinoda K
- Organizer
  The 16th International Neuro-ophthalmology Society Meeting
- Place of Presentation
  Tokyo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390103
[Presentation] Myosin Motor Myolc and Its Receptor NEMO/IKK- γ Promote TNF-α Induced Insulin Resistance Via Phosphorylation of IRS-1 at Serine^<307>.2006
- Author(s)
  Nakamori Y, Emoto M, Fukuda N, Taguchi A, Okuya S, Tanizawa Y
- Organizer
  66th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Washington DC, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390103
[Presentation] GLUT4調節因子 DOC2bはaPKCにより調節され個体糖恒常性を維持する
- Author(s)
  野見山隆太、江本政広、福田尚文、松井久未子、坂根亜由子、三好　淳、佐々木卓也、谷澤幸生
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場　(福岡市）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25461356

1. OKA Yoshitomo (70175256)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
2. TANABE Katsuya (00397994)

# of Collaborated Projects: 8 results

# of Collaborated Products: 97 results
3. OTA Yasuhru (60448280)

# of Collaborated Projects: 7 results

# of Collaborated Products: 97 results
4. UEDA Kohei (50325221)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. YUJIRI Toshiharu (80346551)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
6. KATAGIRI Hedeki (00344664)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
7. MATSUBARA Atsushi (40311815)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. EMOTO Masahiro (50294640)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. TAKEDA Koumei (60467793)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. OKUYA Shigeru (20214083)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. MATSUTANI Akira (10190464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. INOUE Hiroshi (20294639)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. 野見山淳 (70363116)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. YOSHIDA Tuyoshi

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. SAKAKI Terumasa

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. TAGUCHI Akihiko (20634744)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
17. HINOKIO Yoshinori (10282071)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
18. HIRAI Masashi (80312578)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
19. ISHIHARA Hisamitsu (60361086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
20. TURU Masatoshi (20379960)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 幡中雅行 (60572534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 39 results
22. 井上康 (10176448)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
23. 矢賀健 (10166473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. 秋山優 (90717547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
25. ZAITU Yuzuru

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
26. INUKAI Koichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
27. FUKUDA Naofumi (50566867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
28. TAKAHASHI Kazuma (60292215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. ICHIHARA Kiyoshi (10144495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 加来浩平 (10116709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 浅野知一郎 (70242063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 亀井信二 (30314800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 青木稔 (70304475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 齋藤貴之 (80375542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 川口鎮司 (90297549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 村上博和 (40166260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 曽根博仁 (30312846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. TAKEUCHI Yasuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. TAKEUCHI Hideo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. DAVID James E

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. NAKAI Kazuaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. KUROKAWA Kazuyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 財津謙

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. MICHAEL P.Cz

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
45. JAMES E.Davi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 松本健

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. NISHIMURA Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
48. SASAKO Takayoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. 菅原一真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 山下裕司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 山本薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 植木浩二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanizawa Yukio 谷澤 幸生

TANIZAWA Yukio 谷澤 幸生

谷沢 幸生 タニザワ ユキオ

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From Cellular Stress to beta-cell failure and insulin resistance: Investigation of new mechanismsPrincipal Investigator

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Peripheral Circadian Dysregulation and Metabolic DisordersPrincipal Investigator

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Investigation of the mechanism of beta-cell failure in diabetes using Wolfram Syndrome as a modelPrincipal Investigator

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Investigation of the mechanism of pancreatic beta-cell death underlying progressive nature of type 2 diabetes mellitus, aiming at the development of treatment strategy for the disease condition.Principal Investigator

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GLUT4小胞のインスリン・カルシウム依存性膜融合を促進する新規蛋白の同定と解析Principal Investigator

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Investigation of insulin resistance-induced endoplasmic reticulum stress in the pancreatic β-cell and development of diabetes mellitusPrincipal Investigator

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ゲノム資源を用いた糖尿病発症遺伝素因としてのERストレス関連分子の探求Principal Investigator

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Molecular Pathophysiology of Wolfram Syndrome and Endoplasmic Reticulum Stress-associated Pancreatic β-cell Failure.Principal Investigator

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Investigation of the roles of WFS1 and glutamate dehydorogenase on the pancreatic β-cell function and regulation of insulin secretionPrincipal Investigator

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Tanizawa Yukio 谷澤幸生

TANIZAWA Yukio 谷澤幸生

谷沢幸生タニザワユキオ