Sakai Yasuyuki 酒井康行

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SAKAI Yasuyuki 酒井康行

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Researcher Number	00235128
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院工学系研究科(工学部), 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 大学院工学系研究科(工学部), 教授 2015: 東京大学, 工学(系)研究科(研究院), 教授 2007 – 2014: The University of Tokyo, 生産技術研究所, Professor 2007: The University of Tokyo, 大学院・医学系研究科, 准教授 2006: 東京大学, 医学系研究科, 准教授 … More 2006: 東京大学, 大学院医学系研究科, 助教授 2004 – 2005: 東京大学, 大学院・医学系研究科, 助教授 2001 – 2005: The University of Tokyo, Industrial Institute for Science, Assist. Professor, 生産技術研究所, 助教授 2001 – 2003: 東京大学, 大学院・工学系研究科, 助教授 1999 – 2000: 東京大学, 生産技術研究所, 講師 1991 – 1997: 東京大学, 生産技術研究所, 助手 Less
Review Section/Research Field	Principal Investigator 生物・生体工学 / Biofunction/Bioprocess / Science and Engineering / Biomedical engineering/Biological material science / Basic Section 27040:Biofunction and bioprocess engineering-related / Basic Section 90110:Biomedical engineering-related / Nano/Microsystems / Microdevices/Nanodevices / Medium-sized Section 90:Biomedical engineering and related fields / Transformative Research Areas, Section (II) … More / Biofunction/Bioprocess / 環境影響評価(含放射線生物学) / Environmental impact assessment / Risk sciences of radiation/Chemicals / Biomedical engineering/Biological material science … More Except Principal Investigator 反応・分離工学 / 環境影響評価(含放射線生物学) / Basic Section 90110:Biomedical engineering-related / Medium-sized Section 90:Biomedical engineering and related fields / General surgery / Microdevices/Nanodevices / 生物・生体工学 / Basic Section 90120:Biomaterials-related / Medium-sized Section 28:Nano/micro science and related fields / Transformative Research Areas, Section (II) / Biofunction/Bioprocess / Production engineering/Processing studies / Digestive surgery / 広領域 / 反応工学 / Properties in chemical engineering process/Transfer operation/Unit operation / Thermal engineering / Biomedical engineering/Biological material science Less
Keywords	Principal Investigator 生物・生体工学 / 肝細胞 / 灌流培養 / 細胞・組織 / 移植 / 組織工学 / 環境水 / スフェロイド / 細胞毒性 / 幹細胞 … More / ヒトiPS細胞 / 三次元培養 / 腎臓 / 臓器間相互作用 / 肝臓 / 小腸 / チトクロームP450 / 極性輸送 / 代謝活性化 / 肺胞 / 移植・再生医療 / 再生医学 / 再生医療 / 肝組織 / 医用化学工学 / 代謝 / 灌流共培養 / 肝組織工学 / 組織ユニット / 浮遊粒子状物質 / ベンゾ[a]ピレン / 亜急性毒性 / ラット肝細胞 / 重金属蓄積量 / 重金属 / 動物細胞 / 肝細胞分化 / 透析 / 肝分化 / 未分化増幅 / 透析操作 / 高密度培養 / 大量培養 / 前駆細胞 / 自己組織化 / 発生 / バイオマテリアル / オルガノイド / drug screening / iver-on-chip / hepatic differentiation / 成熟化 / マイクロバイオリアクター / iPS細胞 / LIVER / CRCAN-ON-CHID / transport / metabolism / microfludic / hepatocyte / ゾネーション / 多核 / 肝機能 / 創薬支援デバイス / 相互作用 / 臓器チップ / 数理モデル化 / マイクロフィジオロジカルシステム / 血管配備 / 人工臓器 / 内分泌 / 移植デバイス / 血流 / 多孔質担体 / ハイドロゲル / 内分泌組織 / 生体医工学 / Microtox / umu test / PBPK simulation model / Benzolalovrene / shim ulator / absorption and biotransformation / Perfusion cocultivation / 薬物代謝酵素 / 人体代謝シュミレータ / バイオハイブリッド / 生理学的薬物・毒物動力学モデル / 小腸膜 / マイクロトックス法 / umuテスト / 薬物動力学モデル / ベンツ[a]ピレン / シミュレータ / 吸収代謝 / 複合灌流培養 / Numerical simulation / Cytochrome P450 / Suspended particular matter / intake / damage to the lung / ir-liquid interface culture / Air way / Alveolus / 有機溶媒 / バイオアッセイ / 肺気道上皮 / 肺胞上皮 / 浮遊粒子状物体 / 数理モデル / 取り込み / 肺障害 / 気液界面培養 / 肺気道 / oral intake / perfusion culture / static culture / active transport / bioactivation / multi-compartment cell culture system / model liver tissue / model small intestine / アセトアミノフェン / 吸収 / 小腸上皮 / 毒性発現 / 経口吸収 / 静置培養 / 複合細胞培養 / モデル肝組織 / モデル小腸膜 / 面密度 / マクロファージ / 上皮細胞 / 経肺吸収 / 肺吸収 / ナノ粒子 / 培養モデル / 薬学 / 環境 / 胆管ネットワーク / 極性 / 胆管 / 球状凝集体 / 胆管上皮細胞 / マクロ組織極性 / 細胞・組織工学 / 組織 / 生物・生体プロセス / 細胞 / 流路ネットワーク / 人工赤血球 / 三次元造形 / 肝 / 膵島 / マルチスケール血管網配備 / 人工脂肪カプセル / 人工肝カプセル / 肝ミクロソーム / 分布 / バイオリアクター / マイクロ・ナノデバイス / システムオンチップ / ES細胞 / 血流導入 / 酸素供給 / 液性因子 / 三次元担体 / 胎児肝細胞 / 蛍光イメージング / 脂肪細胞 / 動態 / 分配 / マイクロ流体デバイス / オンチップ人体 / アビジン・ビオチン結合 / ヘテロ組織ユニット / マイクロデバイス / 光ピンセット / アビジン・ビオチン反応 / 透過率 / 半透膜培養器 / Bewo細胞 / 多環芳香族炭化水素 / 能動輸送 / 受動輸送 / 栄養芽細胞 / 肝組織再構築 / 血管内皮細胞成長因子 / 生分解性ポリマー / バイオハイブリッド組織 / 組織再構築 / in vitro / 血管新生 / 血管内皮細胞 / マイクロカプセル / 生分解性樹脂 / ポリイソプロピルアクリルアミド / ファイブロネクチン / 増殖 / 温度感受性ゲル / ヒト肝細胞株 / 上水処理プロセス / 臓器特異毒性 / ヒト神経細胞株 / ヒト線維芽細胞株 / 暴露時間 / 機能毒性 / 一般細胞毒性 / 急性毒性 / ヒト細胞 / アルブミン分泌 / ヒト肝細胞 / 種差 / 毒物応答 / 旋回培養 / 迅速形成 / 混合培養 / 非実質細胞 / 実質細胞 / 特異機能 / 長期毒性 / 環境汚染物質 … More Except Principal Investigator 再生医療 / ハイブリッド型人工肝臓 / 組織工学 / 人工肝臓 / Bioartificial liver / 細胞培養 / 細胞培養工学 / アメリカ合衆国 / 生体医工学 / 生体医工学関連 / EGFP / Bioreactor / Hybrid bioartificial liver / 不織布充填型バイオリアクター / ブタ肝細胞 / バイオリアクター / PSA / 膜分離 / マイクロ流体デバイス / 日米比較 / 産業化 / 農薬 / 肝細胞 / バイオアッセイ / 子宮再生 / iPSCs / Liver / MicroPhysiologicalSystem / multi cellular cultures / disease model / pluripotent stem cells / liver on chip / liver / organ on chip / liver disease model / hepatic disorders / hiPSCS / fatty acids / fibrosis / stem cells / liver organ on chip / BioMEMS / 膵β細胞 / BIOMEMS / バイオイメージング / バイオセンシング / TFT電極アレイ / 3Dプリンター / ３Dプリンター / 拡大培養 / 発生 / 細胞工学 / 幹細胞 / 前駆細胞 / オルガノイド / 創薬支援デバイス / 腎臓 / バイオ機能応用およびバイオプロセス工学関連 / バイオ機能応用およびバイオプロセス　工学関連 / バイオ機能応用およびバイオプロセス工学関連 / 組織 / 保存 / 凍結 / 細胞 / 膵液 / ハイドロゲル / 膵臓がん / バイオマテリアル / 医用化学工学 / Regenerative Medicine / Rapid Prototyping / Additive Manufacturing Technologies / 瀬既往造形 / ラピッドプロトタイピング / 積層造形 / Albumin / Plasma exchange / Hemodiafiltration / 肝不全 / アルブミン / 血漿交換 / 血液透析濾過 / Stimuli responsive polymer / Supennolecules / Chemical signal / Tissue engineering / Plasma-graft polymerization / 新陳代謝 / クラウンエーテル / ホストゲスト / 環境応答ゲル / 生体類似膜 / 環境応答性ポリマー / 超分子 / イオンシグナル / ティッシュエンジニアリング / プラズマグラフト重合 / human albumin DNA / Transgenic pig / Transgenic mouse / Transgenic animal / マイクロマニピュレーション / トランスジェニック / トランスジェニックブタ / トランスジェニックマウス / EGFP遺伝子 / ヒトアルブミン遺伝子 / トランスジェニック・ブタ / トランスジェニック・マウス / 形質転換動物 / Direct hemoperfusion treatment / porcine hepatocyte / A non woven fabric bioreactor / ハイブリッド型人工肝臓システム / 異種全血直接灌流治療 / 異種潅流治療 / 全血直接潅流治療 / ハイブリット型人工肝臓 / 全血直接灌流治療 / ハイブリッド型人工臓器 / Glucose / Blood Brain Barrier / Brain / Stress / パルス応答 / グルコース / 血液脳関門 / 脳 / ストレス / Polyesten nan-woven fabric / ブタ肝不全モデル / ブタ肝細胞スフェロイド / 同種灌流治療 / 同種潅流治療 / 肝細胞スフェロイド / ポリエステル不織布 / Bioassay / Toxicity / Pesticide / Animal Cell / 機能変化 / 毒性評価 / 水環境 / 形態変化 / 神経細胞 / 毒性 / 動物細胞 / Zeolite / Carbon Dioxide / Air Separation / Pressure Swing Adsorption / 高速吸脱着サイクル / 圧力スイング吸着法 / ゼオライト / 二酸化炭素 / 空気分離 / 圧力スイング吸着 / Activated Carbon / Water Treatment / Membrane Separation / Membrane / 複合膜 / カーボン膜 / PTFE膜 / 薄膜 / 微粒子 / 排安水 / 活性炭 / 水処理 / 膜 / Collagen gel / Hollow fiber module / Rapid and large-scale formation / Spheroid / High-density culture / Large-scale culture / Liver cells in primary culture / 浮遊サンドイッチコラ-ゲンゲル培養 / 肝シミュレ-タ- / 固定化 / スフェロイド培養 / コラーゲンゲル / ホローファイバーモジュール / 大量迅速形成 / スフェロイド / 高密度培養 / 大量培養 / 初代培養肝細胞 / ドラッグスクリーニング / 細胞アッセイ / in vitro組織モデル / Organ on a chip / 肝代謝モデル / バイオＭＥＭＳ / ヘモグロビン / 人工赤血球 / 膜乳化 / ADME / 薬物動態 / Body on a Chip / バイオMEMS / 光造形 / 形態設計理論 / 大規模集積流路 / 流動抵抗 / scaffold / 人工臓器 / 足場 / マテリアル / デバイス / バイオミメティックス / 生物工学 / リアクター / ベンチャービジネス / アンケート調査 / 毒性発現 / 代謝 / 透過 / 複合培養 / 線維芽細胞 / 小腸上皮細胞 / 動物細胞培養 / 水質評価 / 模擬人体 / 人体影響評価 Less

平滑筋機能に着目した真に着床・妊娠を可能とする再生子宮
- Principal Investigator
  
  古川克子
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Tokyo Institute of Technology
  The University of Tokyo
Mathematical Dynamic Modeling of Heterogeneous Liver Cells
- Principal Investigator
  
  杉本昌弘
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Keio University
Limitations of ultra-high density and low cost in amplification and differentiation of human iPS cellsPrincipal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  The University of Tokyo
Liver fibrosis investigation using iPSCs hepatic derived organ on chip
- Principal Investigator
  
  LECLERC Eric
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Development of "instant" cells and tissues
- Principal Investigator
  
  Nishikawa Masaki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Investigation of high spatiotemporal resolution multi-biosensing method using TFT electrode array
- Principal Investigator
  
  TIXIER-MITA AGNES
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 28:Nano/micro science and related fields
- Research Institution
  The University of Tokyo
Elucidation of the physiological role of heterogeneous hepatocytes and its application to drug discovery and medicinePrincipal Investigator
- Principal Investigator
  
  Sakai Yasuyuki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
Support of virtual human development project
- Principal Investigator
  
  Sugimoto Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Tokyo Medical University
Crosstalks between different organs cultured in OrganS on-a-chipPrincipal Investigator
- Principal Investigator
  
  Sakai Yasuyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Development of implantable kidney organoids
- Principal Investigator
  
  Nishikawa Masaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
血管・尿排泄経路を有する次世代腎臓オルガノイドの作成Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokyo
Development of a new pancreatic fistula prevention material via pancreatic fluid-responsive crosslinking
- Principal Investigator
  
  Ito Taichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Universal implantation platform of regenerated endocrine tissues with rapid hormone secretion through blood flowPrincipal Investigator
- Principal Investigator
  
  Sakai Yasuyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Development of a microfluidic biochip for hepatic induced pluripotent stem cell differentiationPrincipal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Nano/Microsystems
- Research Institution
  The University of Tokyo
Development of physiological lung epithelial modelPrincipal Investigator
- Principal Investigator
  
  Sakai Yasuyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Environmental impact assessment
- Research Institution
  The University of Tokyo
生体様の代謝と輸送を再現する肝組織マイクロデバイスPrincipal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Microdevices/Nanodevices
- Research Institution
  The University of Tokyo
An on-chip hepatic metabolism model for pharmacokinetic studies
- Principal Investigator
  
  KIMURA Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Microdevices/Nanodevices
- Research Institution
  Tokai University
Development of a novel artificial red blood cell via membrane emulsification technique
- Principal Investigator
  
  ITO Taichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Properties in chemical engineering process/Transfer operation/Unit operation
- Research Institution
  The University of Tokyo
Establishment of the methodology for design and growth of implantable pancreatic beta cell or liver cell tissues in vitroPrincipal Investigator
- Principal Investigator
  
  SAKAI Yasuyuki
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
Integrated in vit-roin vivo organization of liver tissues having a functional bile duct networkPrincipal Investigator
- Principal Investigator
  
  SAKAI Yasuyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Integrated "Body on a Chip" system for cell-based assay
- Principal Investigator
  
  KIMURA Hiroshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Microdevices/Nanodevices
- Research Institution
  The University of Tokyo
人工肝・脂肪細胞カプセルと人工小腸膜を導入した実用的オンチップ人体Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Feasibility of implantable liver tissues having a vascular-like blood flow networkPrincipal Investigator
- Principal Investigator
  
  SAKAI Yasuyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
ヒト個体システムの制御応答研究ツールとしての培養細胞利用型オンチップ人体Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  The University of Tokyo
Research on Fabrication of Tissue Engineering Scaffold for Reconstruction of Internal Organs with High Metabolic Rate by Laser Sintering Solid Freeform Fabrication and Cell Culture
- Principal Investigator
  
  NIINO Toshiki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Production engineering/Processing studies
- Research Institution
  The University of Tokyo
アビジン・ビオチン反応を利用した階層構造を持つ三次元組織ユニットの作製Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
人工臓器における大規模集積流路ネットワークの形態設計・評価に関する研究
- Principal Investigator
  
  SHIRAKASHI Ryo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Thermal engineering
- Research Institution
  The University of Tokyo
Preclinical experiment and clinical trial of bioartificial liver.
- Principal Investigator
  
  NARUSE Katsutoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
組織工学的アプローチによる新規バイオミメティック組織デバイス開発の現状と課題
- Principal Investigator
  
  高木睦
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Osaka University
環境汚染物質の胎児移行性の簡便評価に適したin vitro血液胎盤関門モデルPrincipal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  The University of Tokyo
ティッシュエンジニアリングによる組織再生の医療応用における工学的課題調査
- Principal Investigator
  
  高木睦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
化学・生物工学的観点からの組織工学のポテンシャル評価-再生医療技術に関する分野横断的研究動向の調査-
- Principal Investigator
  
  高木睦
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  Osaka University
Novel regenerable cell culture system using signal responsive membrane substrate
- Principal Investigator
  
  YAMAGUCHI Takeo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  反応・分離工学
- Research Institution
  The University of Tokyo
Development of bioassays for gaseous chemicals using air-liquid interface culture of human lung epithelial cellsPrincipal Investigator
- Principal Investigator
  
  SAKAI Yasuyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  The University of Tokyo
Development of a small-scale biohybrid simulator for human metabolism and its application as a newcytotoxicity testing systemPrincipal Investigator
- Principal Investigator
  
  SAKAI Yasuyuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  The University of Tokyo
A study in development of transgenic cattles for the use of hybrid bioartifical liver.
- Principal Investigator
  
  MAKUUCHI Masatoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  The University of Tokyo
血管内皮細胞成長因子徐放カプセルによる類洞構造を持つ肝組織生体外再構築の試みPrincipal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Xenogeneic per fusion experiment and treatment for patients with liver failure using a non woven fabric bioreactor.
- Principal Investigator
  
  MAKUUCHI Masatoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
Development of a multi-compartment cell culture system for quantitative evaluation of chemical impacts to humansPrincipal Investigator
- Principal Investigator
  
  SAKAI Yasuyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  生物・生体工学
- Research Institution
  University of Tokyo
動物細胞を用いた環境水の長期暴露における臓器特異毒性の評価Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
温度感受性ゲルを担体用いた浮遊培養による正常肝細胞の増殖と分化の制御Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  The University of Tokyo
環境汚染物質の人体影響評価のための簡易模擬人体システムの開発に関する基礎研究
- Principal Investigator
  
  鈴木基之
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  The University of Tokyo
培養動物細胞を用いた環境水の人体影響評価Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of a new bioartificial liver module
- Principal Investigator
  
  MUTO Tetsuichiro
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  University of Tokyo
Fundamental Engineering Study on Effects of Stress on Brain Metabolism
- Principal Investigator
  
  SAKODA Akiyoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Tokyo
動物細胞を用いた環境水と毒性物質の複合的な毒性に関する研究Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
特異機能を保持するヒト及びラット肝細胞を用いた毒物応答の種間差異に関する研究Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  The University of Tokyo
Development of Microsphere-aggregated Menbrane and its Filtration Characteristics
- Principal Investigator
  
  SUZUKI Motoyuki
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  反応・分離工学
- Research Institution
  University of Tokyo
Development of Ultra Rapid Pressure Swing Adsorption
- Principal Investigator
  
  SUZUKI Motoyuki
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  反応・分離工学
- Research Institution
  University of Tokyo
Development of Methodology for Evaluating Toxicity of Pesticides by Responses of Animal Cells
- Principal Investigator
  
  SAKODA Akiyoshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  University of Tokyo
動物細胞の機能変化を指票とする環境水汚染物質の長期毒性評価に関する研究Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
より生体に近い構造と高度な機能を持つ肝細胞凝集体の迅速大量形成に関する研究Principal Investigator
- Principal Investigator
  
  酒井康行
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  生物・生体工学
- Research Institution
  The University of Tokyo
High-Density and Large-Scale Culture of Mammalian Liver Cells
- Principal Investigator
  
  SUZUKI Motoyuki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  反応工学
- Research Institution
  University of Tokyo

[Book] Fetal Tissue Transplantation in Fetal Tissue Transplantation（分担執筆）,2013
- Author(s)
  Y. Sakai1, J. Jiang, S. Hanada, H. Huang, T. Katsuda, N. Kojima, T. Teratani, A. Miyajima, T. Ochiya
- Total Pages
  221
- Publisher
  Springer-Verlag UK
- Data Source
  KAKENHI-PROJECT-22650108
[Book] Springer-Verlag UK,2212013
- Author(s)
  Y. Sakai, J. Jiang, S. Hanada, H. Huang,T.Katsuda, N. Kojima, T. Teratani, A.Miyajima, T.Ochiya
- Total Pages
  221
- Publisher
  Fetal TissueTransplantation in Fetal TissueTransplantation
- Data Source
  KAKENHI-PROJECT-22650108
[Book] 先端バイオマテリアルハンドブック「第4章：医療計測用バイオマテリアル，第13節：マイクロ流体デバイス技術を応用したin vitro生体モデルの構築」2012
- Author(s)
  木村啓志，酒井康行，藤井輝夫
- Total Pages
  656
- Publisher
  エヌティーエス出版
- Data Source
  KAKENHI-PROJECT-24710141
[Book] "第4章:医療計測用バイオマテリアル,第13節:マイクロ流体デバイス技術を応用したin vitro生体モデルの構築",先端バイオマテリアルハンドブック2012
- Author(s)
  木村啓志, 酒井康行, 藤井輝夫, 書籍分担執筆
- Publisher
  エヌティーエス出版
- Data Source
  KAKENHI-PROJECT-24710141
[Book] in"Liver StemCells"etd. by T. Ochiya, Hamana Press2011
- Author(s)
  Y.Sakai, M.Nishikawa, F.Evenou, M.Hamon,H.Huang, K.P.Montagne, N.Kojima, T.Fujiiand T.Niino
- Total Pages
  236
- Publisher
  Engineering of implantableliver tissues
- Data Source
  KAKENHI-PROJECT-22650108
[Book] "Engineering of implantable liver tissues", in "Liver Stem Cells"(etd. by T. Ochiya)2011
- Author(s)
  Y.Sakai, M.Nishikawa, F.Evenou, M.Hamon, H.Huang, K.
- Publisher
  Hamana Press
- Data Source
  KAKENHI-PROJECT-22246101
[Book] 第18章,血流導入型体内埋め込み組織の構築,「細胞治療・再生医療のための培養システム」(紀ノ岡正博,酒井康行監修)2011
- Author(s)
  酒井康行, 新野俊樹(分担執筆)
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22246101
[Book] "Engineering of implantable liver tissues", in "Liver Stem Cells"(etd.by T.Ochiya)2011
- Author(s)
  Y.Sakai, M.Nishikawa, F.Evenou, M.Hamon, H.Huang, K.P.Montagne, N.Kojima, T.Fujii, T.Niino
- Publisher
  Hamana Press
- Data Source
  KAKENHI-PROJECT-22650108
[Book] 第5章:バイオチップの将来技術、第9節:機能集積型マイクロ流体デバイスの細胞培養への応用、バイオチップ実用化ハンドブック2010
- Author(s)
  木村啓志、山本貴富喜、竹内昌治、酒井康行、藤井輝夫
- Publisher
  エヌティーエス出版
- Data Source
  KAKENHI-PROJECT-22710120
[Book] 第18章, 血流導入型体内埋め込み組織の構築, 細胞治療・再生医療のための培養システム (紀ノ岡正博・酒井康行監修)2010
- Author(s)
  酒井康行, 新野俊樹 (分担執筆)
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-19360371
[Book] バイオチップ実用化ハンドブック(分担執筆)「第5章:バイオチップの将来技術,第9節:機能集積型マイクロ流体デバイスの細胞培養への応用」2010
- Author(s)
  木村啓志, 山本貴富喜, 竹内昌治, 酒井康行, 藤井輝夫
- Total Pages
  610
- Publisher
  エヌティーエス出版
- Data Source
  KAKENHI-PROJECT-22710120
[Book] 第18章,血流導入型体内埋め込み組織の構築,pp.159-166,細胞治療・再生医療のための培養システム紀ノ岡正博, 酒井康行監修2010
- Author(s)
  酒井康行, 新野俊樹(分担執筆)
- Total Pages
  320
- Publisher
  シーエムシー出版,大阪
- Data Source
  KAKENHI-PROJECT-19360371
[Book] 未分化肝細胞を用いた異所的な肝組織の再構築とその制御, 遺伝子医学MOOK別冊, 進み続ける細胞移植治療の実際―再生医療の実現に向けた科学・技術の周辺要素の理解―2008
- Author(s)
  小島伸彦, 酒井康行
- Publisher
  メディカルDo
- Data Source
  KAKENHI-PROJECT-19360371
[Book] Precise tissue assembly using avidin-biotin binding system and optical tweezers (in Advances in Medical Engineering, Drug Delivery Systems and Therapeutic Systems) (pp. 200-203) (N.A. Peppas, A.S. Hoffman, T. Kanamori and K. Tojo, eds)2006
- Author(s)
  Nobuhiko Kojima, Tomoki Matsuo, Hiroaki Suzuki, Shoji Takeuchi, Yasuyuki Sakai
- Total Pages
  4
- Publisher
  American Institute of Chemical Engineers, New York, NY, USA
- Data Source
  KAKENHI-PROJECT-17650130
[Journal Article] Dynamic, IPSC-derived hepatic tissue tri-culture system for the evaluation of liver physiology in vitro2024
- Author(s)
  Scheidecker Benedikt、Poulain Stephane、Sugimoto Masahiro、Kido Taketomo、Kawanishi Takumi、Miyajima Atsushi、Kim Soo Hyeon、Arakawa Hiroshi、Kato Yukio、Nishikawa Masaki、Danoy Mathieu、Sakai Yasuyuki、Leclerc Eric
- Journal Title
  
  Biofabrication
  
  Volume: 16 Issue: 2 Pages: 025037-025037
- DOI
  10.1088/1758-5090/ad30c5
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K25188
[Journal Article] Vascularization of Kidney Organoids: Different Strategies and Perspectives2024
- Author(s)
  Raykhel I, Skovorodkin I, Nishikawa M, Sakai Y, Vainio S
- Journal Title
  
  Frontiers In Urology
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04499
[Journal Article] Transcriptomic and proteomic studies suggest the establishment of advanced zonation‐like profiles in humaninduced pluripotent stem cell‐derived liver sinusoidal endothelial cells and carboxypeptidase M‐positive liver progenitor cells cocultured in a fluidic microenvironment2023
- Author(s)
  Danoy M, Poulain S, Scheidecker B, Kim SH, Kido T, Miyajima A, Sakai Y, Leclerc E
- Journal Title
  
  Hepatology research
  
  Volume: 1 Issue: 7 Pages: 1-14
- DOI
  10.1111/hepr.13893
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25188, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710
[Journal Article] Particle-tracking-based strategy for the optimization of agitation conditions in a suspension culture of human induced pluripotent stem cells in a shaking vessel2023
- Author(s)
  Horiguchi Ikki、Nagate Hotaka、Sakai Yasuyuki
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 135 Issue: 5 Pages: 411-416
- DOI
  10.1016/j.jbiosc.2023.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K04507, KAKENHI-PROJECT-23K23144
[Journal Article] Dialysis based-culture medium conditioning improved the generation of human induced pluripotent stem cell derived-liver organoid in a high cell density2022
- Author(s)
  Fuad Gandhi Torizal, Tia Utami, Lau Qiau You, Kousuke Inamura, Masaki Nishikawa, and Yasuyuki Sakai
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 20774-20774
- DOI
  10.1038/s41598-022-25325-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K23144
[Journal Article] Computational simulation of liver fibrosis dynamics2022
- Author(s)
  Yoshizawa Misa、Sugimoto Masahiro、Tanaka Minoru、Sakai Yusuyuki、Nishikawa Masaki
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 14112-14112
- DOI
  10.1038/s41598-022-18123-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05743, KAKENHI-PLANNED-20H05744, KAKENHI-PROJECT-22H00595
[Journal Article] Current status of MPS research toward social implementation2022
- Author(s)
  酒井康行，木村啓志
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 157 Issue: 5 Pages: 330-334
- DOI
  10.1254/fpj.22046
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-18H01849
[Journal Article] Real-time High-resolution Measurement of Pancreatic β Cell Electrophysiology Based on Transparent Thin-film Transistor Microelectrode Arrays2022
- Author(s)
  Dongchen Zhu, Anne-Claire Eiler, Satoshi Ihida, Yasuyuki Sakai, Hiroshi Toshiyoshi, Agnes Tixier-Mita, and Kikuo Komori
- Journal Title
  
  IEEJ Transactions on Sensors and Micromachines
  
  Volume: 142 Issue: 10 Pages: 266-272
- DOI
  10.1541/ieejsmas.142.266
- ISSN
  1341-8939, 1347-5525
- Year and Date
  2022-10-01
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18869
[Journal Article] Simulation of the crosstalk between glucose and acetaminophen metabolism in a liver zonation model2022
- Author(s)
  Maeda Kazuhiro、Hagimori Shuta、Sugimoto Masahiro、Sakai Yasuyuki、Nishikawa Masaki
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13 Pages: 995597-995597
- DOI
  10.3389/fphar.2022.995597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05743, KAKENHI-PROJECT-22H00595
[Journal Article] Influence of CPM-dependent sorting on the multi-omics profile of hepatocyte-like cells matured in microscale biochips2022
- Author(s)
  Mathieu Danoy、Stephane Poulain、Benedikt Scheidecker、Rachid Jellali、Yannick Tauran、Marjorie Leduc、Johanna Bruce、Francoise Gilard、Bertrand Gakiere、Hiroshi Arakawa、Yukio Kato、Soo Hyeon Kim、Taketomo Kido、Atsushi Miyajima、Yasuyuki Sakai、Eric Leclerc
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume: 181 Pages: 108408-108408
- DOI
  10.1016/j.bej.2022.108408
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22491, KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-21H02710
[Journal Article] Accurate evaluation of hepatocyte metabolisms on a noble oxygen-permeable material with low sorption　characteristics2022
- Author(s)
  Benedikt Scheidecker, Mathieu Danoy, Takumi Kawanishi, Hirohsi Arakawa, Yukio Kato, Katsuhiro Esashika, Hiroshi Miyasako, Yasuyuki Sakai
- Journal Title
  
  Frontiers in Toxicology
  
  Volume: 4 Pages: 810478-810478
- DOI
  10.3389/ftox.2022.810478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05745
[Journal Article] Cryopreserved human hepatocytes culture optimization on polymethylpentene oxygen permeable membranes for drug screening purposes2022
- Author(s)
  Mathieu Danoy, Benedikt Scheidecker, Hiroshi Arakawa, Katsuhiro Esashika, Naoki Ishida, Hiroyasu Ito, Hisaaki Yanai, Jun Takahashi, Masaki Nishikawa, Yukio Kato, Yasuyuki Sakai
- Journal Title
  
  Fundamental Toxicological Sciences
  
  Volume: 9 Issue: 4 Pages: 135-144
- DOI
  10.2131/fts.9.135
- ISSN
  2189-115X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05745
[Journal Article] Prospect of in vitro Bile Fluids Collection in Improving Cell-Based Assay of Liver Function2021
- Author(s)
  Rizki-Safitri Astia、Tokito Fumiya、Nishikawa Masaki、Tanaka Minoru、Maeda Kazuya、Kusuhara Hiroyuki、Sakai Yasuyuki
- Journal Title
  
  Frontiers in Toxicology
  
  Volume: 3 Pages: 657432-657432
- DOI
  10.3389/ftox.2021.657432
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03401, KAKENHI-PLANNED-20H05745
[Journal Article] Multi-omics analysis of hiPSCs-derived HLCs matured on-chip revealed patterns typical of liver regeneration2021
- Author(s)
  Danoy M, Tauran Y, Poulain S, Jellali R, Bruce J, Leduc M, Gall M, Koui Y, Arakawa H, Gilard F, Kato Y, Kido T, Miyajima A, Sakai Y, Leclerc E
- Journal Title
  
  Biotechnology & Bioengineering
  
  Volume: 118 Issue: 10 Pages: 3716-3732
- DOI
  10.1002/bit.27667
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-16H06328, KAKENHI-PROJECT-21H02710
[Journal Article] Sessile Liquid Marbles with Embedded Hydrogels as Bioreactors for Three‐Dimensional Cell Culture2021
- Author(s)
  Vadivelu Raja、Kashaninejad Navid、Nikmaneshi Mohammad Reza、Khadim Rubina Rahaman、Salehi Seyedeh Sarah、Ramulu Naveen Chintala、Sakai Yasuyuki、Nishikawa Masaki、Firoozabadi Bahar、Nguyen Nam‐Trung
- Journal Title
  
  Advanced Biology
  
  Volume: 5 Issue: 2 Pages: 2000108-2000108
- DOI
  10.1002/adbi.202000108
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19F19363
[Journal Article] Production of homogenous size‐controlled human induced pluripotent stem cell aggregates using ring‐shaped culture vessel2021
- Author(s)
  Torizal Fuad Gandhi、Kim Seong Min、Horiguchi Ikki、Inamura Kousuke、Suzuki Ikumi、Morimura Takashi、Nishikawa Masaki、Sakai Yasuyuki
- Journal Title
  
  Journal of Tissue Engineering and Regenerative Medicine
  
  Volume: 16 Issue: 3 Pages: 254-266
- DOI
  10.1002/term.3278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05744, KAKENHI-PROJECT-23K23144
[Journal Article] 概論＝真に生理学的なOrgan on-a-chip実現のために2021
- Author(s)
  酒井康行
- Journal Title
  
  実験医学
  
  Volume: 39 Pages: 2563-2566
- Data Source
  KAKENHI-PLANNED-20H05745
[Journal Article] Sessile Liquid Marbles: Sessile Liquid Marbles with Embedded Hydrogels as Bioreactors for Three‐Dimensional Cell Culture (Adv. Biology 2/2021)2021
- Author(s)
  Vadivelu Raja、Kashaninejad Navid、Nikmaneshi Mohammad Reza、Khadim Rubina Rahaman、Salehi Seyedeh Sarah、Ramulu Naveen Chintala、Sakai Yasuyuki、Nishikawa Masaki、Firoozabadi Bahar、Nguyen Nam‐Trung
- Journal Title
  
  Advanced Biology
  
  Volume: 5 Issue: 2 Pages: 2170022-2170022
- DOI
  10.1002/adbi.202170022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19F19363, KAKENHI-PROJECT-19K23600
[Journal Article] Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system2021
- Author(s)
  Shinohara Marie、Arakawa Hiroshi、Oda Yuuichi、Shiraki Nobuaki、Sugiura Shinji、Nishiuchi Takumi、Satoh Taku、Iino Keita、Leo Sylvia、Kato Yusuke、Araya Karin、Kawanishi Takumi、Nakatsuji Tomoki、Mitsuta Manami、Inamura Kosuke、Goto Tomomi、Shinha Kenta、Nihei Wataru、Komori Kikuo、Sakai Yasuyuki、Kimura Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 5437-5437
- DOI
  10.1038/s41598-021-84861-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H01849, KAKENHI-PLANNED-20H05745, KAKENHI-PROJECT-18H02154
[Journal Article] 概論―真に生理学的なOrgan on-a-chip実現のために特集：真の生理学性に挑むOrgan-on-a-chip2021
- Author(s)
  酒井康行
- Journal Title
  
  実験医学
  
  Volume: 39 Pages: 2563-2566
- Data Source
  KAKENHI-PLANNED-20H05745
[Journal Article] A Kinetic Pump Integrated Microfluidic Plate (KIM-Plate) with High Usability for Cell Culture-Based Multiorgan Microphysiological Systems2021
- Author(s)
  Shinha Kenta、Nihei Wataru、Nakamura Hiroko、Goto Tomomi、Kawanishi Takumi、Ishida Naoki、Yamazaki Nao、Imakura Yuki、Mima Shinji、Inamura Kosuke、Arakawa Hiroshi、Nishikawa Masaki、Kato Yukio、Sakai Yasuyuki、Kimura Hiroshi
- Journal Title
  
  Micromachines
  
  Volume: 12 Issue: 9 Pages: 1007-1007
- DOI
  10.3390/mi12091007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20H05744, KAKENHI-PROJECT-18H01849, KAKENHI-PLANNED-20H05745
[Journal Article] Switching of cell proliferation/differentiation in thiol-maleimide clickable microcapsules triggered by in situ conjugation of biomimetic peptides.2019
- Author(s)
  Oki Y, Kirita K, Ohta S, Ohba S, Horiguchi I, Sakai Y, Ito T
- Journal Title
  
  Biomacromolecules
  
  Volume: 20 Issue: 6 Pages: 2350-2359
- DOI
  10.1021/acs.biomac.9b00333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19635, KAKENHI-PROJECT-16H02419
[Journal Article] Endodermal differentiation of human induced pluripotent stem cells using simple dialysis culture system in suspension culture2019
- Author(s)
  Marie Shinohara, Hyunjin Choi, Masato Ibuki, Shigeharu G.Yabe, Hitoshi Okochi, Atsushi Miyajimam Yasuyuki Sakai
- Journal Title
  
  Regenerative Therapy
  
  Volume: 12 Pages: 14-19
- DOI
  10.1016/j.reth.2019.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02419, KAKENHI-PROJECT-18K18359
[Journal Article] Biodegradable and hollowed micro-scaffolds for improved modular assembly-based tissue engineering: design, 3D fabrication, and feasibility in randomly packed perfusion culture2019
- Author(s)
  Y. Pang, S. Sutoko, Y. Horimoto, D. Weng, K. Montagne, K. Komori, K. Takano, R. Shirakashi, M. Anzai, T. Niino, Y. Sakai
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume: 149 Pages: 107239-107239
- DOI
  10.1016/j.bej.2019.107239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02419
[Journal Article] Size-Controlled Preparation of Microsized Perfluorocarbon Emulsions as Oxygen Carriers via the Shirasu Porous Glass Membrane Emulsification Technique2019
- Author(s)
  Xiaoting Fu, Seiichi Ohta, Masamichi Kamihira, Yasuyuki Sakai, and Taichi Ito
- Journal Title
  
  Langmuir
  
  Volume: 35(11) Issue: 11 Pages: 4094-4100
- DOI
  10.1021/acs.langmuir.9b00194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02419
[Journal Article] Development of Human-derived Hemoglobin/Albumin Microspheres as Oxygen Carriers Using Shirasu Porous Glass Membrane Emulsification2018
- Author(s)
  Seiichi Ohta, Kenichiro Hashimoto, Xiaoting Fu, Masamichi Kamihira, Yasuyuki Sakai, and Taichi Ito
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 128(4) Issue: 4 Pages: 533-539
- DOI
  10.1016/j.jbiosc.2018.04.017
- NAID
  40021697460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02419
[Journal Article] Enhanced self-organization of size-controlled hepatocyte aggregates on oxygen permeable honeycomb microwell sheets2017
- Author(s)
  Marie Shinohara, Kikuo Komori, Teruo Fujii, Yasuyuki Sakai
- Journal Title
  
  Biomedical Physics & Engineering Express
  
  Volume: 3 Issue: 4 Pages: 045017-045017
- DOI
  10.1088/2057-1976/aa7c3d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H02419
[Journal Article] 生体内や培養下における酸素の輸送現象2017
- Author(s)
  酒井康行，篠原満利恵，小森喜久夫
- Journal Title
  
  化学工学
  
  Volume: 81 Pages: 117-119
- Data Source
  KAKENHI-PROJECT-16H02419
[Journal Article] Novel integrative methodology for engineering large liver tissue equivalents based on three-dimensional scaffold fabrication and cellular aggregate assembly2016
- Author(s)
  Y. Pang, Y. Horimoto, S. Sutoko, K. Montagne, M. Shinohara, M. Danoy, K. Komori, M. Anzai, T. Niino, Y. Sakai
- Journal Title
  
  Biofabrication
  
  Volume: 8 Issue: 3 Pages: 16-26
- DOI
  10.1088/1758-5090/8/3/035016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Journal Article] Preparation of uniform-sized hemoglobin-albumin microspheres as oxygen carriers by Shirasu porous glass membrane emulsification technique2015
- Author(s)
  Yao-Tong Lai, Mayu Sato, Seiichi Ohta, Kazuki Akamatsu, Shin-ichi Nakao, Yasuyuki Sakai, Taichi Ito
- Journal Title
  
  Colloids and Surfaces B: Biointerfaces
  
  Volume: 127 Pages: 1-7
- DOI
  10.1016/j.colsurfb.2015.01.018
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22246101, KAKENHI-PROJECT-26420792
[Journal Article] Combination of microwell structures and direct oxygenation enables efficient and size-regulated aggregate formation of an insulin-secreting pancreatic beta-cell line2014
- Author(s)
  M. Shinohara, H. Kimura, K. Montagne, K. Komori, T. Fujii, Y. Sakai
- Journal Title
  
  Biotechnol. Prog.
  
  Volume: 30 Issue: 1 Pages: 178-187
- DOI
  10.1002/btpr.1837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101, KAKENHI-PROJECT-24710141
[Journal Article] マクロ三次元流路ネットワークと小チャンバーからなる組織再構築用担体2014
- Author(s)
  酒井康行、厖媛、堀本洋平、安斎正博，新野俊樹
- Journal Title
  
  バイオインダストリー
  
  Volume: 31 Pages: 45-50
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] 酸素供給に基づいた肝組織の設計と構築2014
- Author(s)
  酒井康行，厖媛，堀本洋平，安斎正博，新野俊樹
- Journal Title
  
  伝熱学会誌
  
  Volume: 53 Pages: 10-15
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] Biliaryepithelial cells play an essential role inthe reconstruction of hepatic tissue witha functional bile ductular network2013
- Author(s)
  Takeshi Katsuda, N. Kojima, TakahiroOchiya, and Yasuyuki Sakai.
- Journal Title
  
  TissueEng. A
  
  Volume: in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Image-based evaluations of distribution and cytotoxicity of Irinotecan (CPT-11) in a multi-compartment micro-cell coculture device2013
- Author(s)
  H. Nakayama, H. Kimura, T. Fujii, Y. Sakai
- Journal Title
  
  J. Biosci. Bioeng.
  
  Volume: 117 Issue: 6 Pages: 756-762
- DOI
  10.1016/j.jbiosc.2013.11.019
- NAID
  110009823163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710141
[Journal Article] Hypoxiaefficiently induces differentiation ofmouse embryonic stem cells into endodermaland hepatic progenitor cells2013
- Author(s)
  Takeshi Katsuda, Takumi Teratani,Mohammad,Mahfuz Chowdhury, TakahiroOchiya, Yasuyuki Sakai
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume: 74 Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Hypoxia efficiently induces differentiation of mouse embryonic stem cells into endodermal and hepatic progenitor cells2013
- Author(s)
  Takeshi Katsuda, Takumi Teratani, Mohammad Mahfuz Chowdhury, Takahiro Ochiya, Yasuyuki Sakai
- Journal Title
  
  Biochemical Engineering Journal
  
  Volume: 74 Pages: 95-101
- DOI
  10.1016/j.bej.2013.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Formation and harvesting of thick pancreatic β-cell sheets on a highly O2-permeable plate modified with poly(N-isopropylacrylamide)2013
- Author(s)
  Kikuo Komori,* Mari Udagawa, Marie Shinohara, Kevin Montagne, Tatsuro Tsuru and Yasuyuki Sakai
- Journal Title
  
  Biomaterials Science
  
  Volume: 1 Issue: 5 Pages: 510-518
- DOI
  10.1039/c3bm00123g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] Liver tissue engineering based on aggregate assembly: efficient formation of endothelialized rat hepatocyte aggregates and their immobilization with biodegradable fibers2012
- Author(s)
  Y. Pang, K. Montagne, M. Shinohara, K. Komori and Y. Sakai
- Journal Title
  
  Biofabrication
  
  Volume: 4 Issue: 4 Pages: 45004-45004
- DOI
  10.1088/1758-5082/4/4/045004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] Rapid aggregation of heterogeneous cells and multiple-sized microspheres in methylcellulose medium2012
- Author(s)
  N. Kojima, S. Takeuchi and Y. Sakai
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 18 Pages: 4508-4514
- DOI
  10.1016/j.biomaterials.2012.02.065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101, KAKENHI-PROJECT-24710142
[Journal Article] Spatiotemporally controlled delivery of soluble factors for stem cell differentiation2012
- Author(s)
  J. Kawada, H. Kimura, H. Akutsu, Y. Sakai, T. Fujii
- Journal Title
  
  Lab on a Chip
  
  Volume: vol.12, no.21 Pages: 4508-4515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24710141
[Journal Article] Laser sintering fabrication of three-dimensional tissue engineering scaffolds with a flow channel network2011
- Author(s)
  T.Niino, D.Hamajima, K.Montagne, S.Oizumi, H.Naruke, H.Huang, Y.Sakai
- Journal Title
  
  Biofabrication
  
  Volume: 3 Issue: 3 Pages: 34-104
- DOI
  10.1088/1758-5082/3/3/034104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101, KAKENHI-PROJECT-23246027
[Journal Article] Avidin-biotin-based approach to forming heterotypic cell clusters and cell sheets on a gas-permeable membrane2011
- Author(s)
  M.Hamon, K.Montagne, N.Kojima, I.Ozawa, R.Ishii, S.Yamaguchi, T.Nagamune, T.Ushida, Y.Sakai
- Journal Title
  
  Biofabrication
  
  Volume: 3 Issue: 3 Pages: 34-111
- DOI
  10.1088/1758-5082/3/3/034111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] Bile canaliculi formation by aligning rat primary hepatocyte in a micro fluidic device2011
- Author(s)
  Y. Nakao、H. Kimura、Y. Sakai、T. Fujii
- Journal Title
  
  Biomicrofluidics
  
  Volume: Vol.5
- URL
  http://dx.doi.org/10.1063/1.3580753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710120
[Journal Article] 脂肪由来幹細胞による細胞治療の可能性2011
- Author(s)
  勝田毅、酒井康行、落谷孝広
- Journal Title
  
  実験医学
  
  Volume: 29 Pages: 3102-3108
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Bile canaliculi formation by aligning rat primary hepatocyte in a microfluidic device2011
- Author(s)
  Y.Nakao, H.Kimura, Y.Sakai, T.Fujii
- Journal Title
  
  Biomicrofluidics
  
  Volume: 5(Web) Issue: 2
- DOI
  10.1063/1.3580753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710120
[Journal Article] Use of liposome encapsulated hemoglobin as an oxygen carrier for fetal and adult rat liver cell culture2011
- Author(s)
  K.Montagne, H.Huang, K.Ohara, K.Matsumoto, A.Mizuno, K.Ohta, Y.Sakai
- Journal Title
  
  J.Biosci.Bioeng
  
  Volume: 112 Pages: 485-490
- NAID
  110008761513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] 異所性体内埋め込み型人工肝臓開発の現状と展望2010
- Author(s)
  勝田毅, 小森喜久夫, 寺谷工, 落谷孝広, 酒井康行
- Journal Title
  
  生産研究(掲載確定) 62(印刷中)
- NAID
  130000342799
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane2010
- Author(s)
  F.Evenou, T.Fujii, Y.Sakai
- Journal Title
  
  Tissue Engineering Part C : Methods 16
  
  Pages: 311-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034013
[Journal Article] Toward engineering of vascularized three-dimensional liver tissue equivalents possessing a clinicallysignificant mass2010
- Author(s)
  Y. Sakai, H. Huang, S. Hanada, T. Niino
- Journal Title
  
  Biochem. Eng.J. 48
  
  Pages: 348-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] 異所性体内埋め込み型人工肝臓開発の現状と展望2010
- Author(s)
  勝田毅、小森喜久夫、寺谷工、落谷孝広、酒井康行
- Journal Title
  
  生産研究
  
  Volume: 62 Pages: 213-217
- NAID
  130000342799
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Spontaneous formation of stably-attached and 3D-organized hepatocyte aggregates on oxygen-permeable polydimethylsiloxane membranes having 3D microstructures2010
- Author(s)
  F.Evenou, T.Fujii, Y.Sakai
- Journal Title
  
  Biomedical Microdevices
  
  Volume: 12 Pages: 465-475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] Toward engineering of vascularized three-dimensional liver tissue equivalents possessing a clinically-significant mass2010
- Author(s)
  酒井康行, H.Huang, 勝田毅, T.Niino
- Journal Title
  
  Biochemical Engineering Journal 48
  
  Pages: 348-361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] Transplantation of fetal livercell-loaded hyaluronic acid sponge ontothe mesentery recovers a Wilson' sdisease model rat2010
- Author(s)
  Katsuda T, Teratani T, Ochiya T, SakaiY
- Journal Title
  
  J Biochem
  
  Volume: 148 Pages: 281-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Spontaneous formation of highly functional three-dimensional multilayer from human hepatoma Hep G2 cells cultured on an oxygen-permeable polydimethylsiloxane membrane2010
- Author(s)
  F.Evenou, T.Fujii, Y.Sakai
- Journal Title
  
  Tissue Engineering Part C : Methods
  
  Volume: 16 Pages: 311-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] 異所性体内埋め込み型人工肝暇開発の現状と展望2010
- Author(s)
  勝田毅, 小森喜久夫, 寺谷工, 落谷孝広, 酒井康行
- Journal Title
  
  生産研究
  
  Volume: 62 Pages: 213-217
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] Direct oxygen supply with polydimethylsiloxane(PDMS)membranes induces a spontaneous organization of thick heterogeneous liver tissues from rat fetal liver cells in vitro2010
- Author(s)
  M.Hamon, 勝田毅, T.Fujii, 酒井康行
- Journal Title
  
  Cell Transplantation ((掲載確定), inpress.)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] 再生医療への化学工学の寄与可能性-組織設計・構築と育成-2010
- Author(s)
  酒井康行, 藤井輝夫, 新野俊樹
- Journal Title
  
  再生医療
  
  Volume: 9 Pages: 361-366
- Data Source
  KAKENHI-PROJECT-22246101
[Journal Article] 肝細胞培養のための生体内環境を模倣したマイクロ流体デバイス2010
- Author(s)
  中尾洋祐, 川田治良, 木村啓志, 酒井康行, 藤井輝夫
- Journal Title
  
  化学とマイクロ・ナノシステム研究会
  
  Volume: 9(2) Pages: 25-26
- Data Source
  KAKENHI-PROJECT-22710120
[Journal Article] 1Yansplantation of a fetal liver ce11-loaded hyaluronic acid spongeonto the mesentery recovers a Wilson's disease model rat2010
- Author(s)
  Katsuda T, Teratani T, OchiyaT, Sakai Y
- Journal Title
  
  J Biochem.
  
  Volume: 148 Pages: 281-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] 肝細胞培養のための生体内環境を模倣したマイクロ流体デバイス2010
- Author(s)
  中尾洋祐、川田治良、木村啓志、酒井康行、藤井輝夫
- Journal Title
  
  化学とマイクロ・ナノシステム研究会誌
  
  Volume: Vol.9No.2 Pages: 25-26
- Data Source
  KAKENHI-PROJECT-22710120
[Journal Article] 間葉系幹細胞を用いた細胞治療の可能性2010
- Author(s)
  勝田毅、酒井康行、落谷孝広
- Journal Title
  
  医工学治療
  
  Volume: 22 Pages: 204-210
- Data Source
  KAKENHI-PROJECT-22650108
[Journal Article] 胚性幹細胞を用いた肝細胞分化誘導研究の現状2009
- Author(s)
  勝田毅, 小森喜久夫, 酒井康行
- Journal Title
  
  生産研究 61
  
  Pages: 116-121
- NAID
  130000102287
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] 胚性幹細胞を用いた肝細胞分化誘導研究の現状2009
- Author(s)
  勝田毅, 小森喜久夫, 酒井康行
- Journal Title
  
  生産研究 61(2)
  
  Pages: 116-121
- NAID
  130000102287
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] 体内毒性試験へ向けたオンチップ小腸-肝臓由来細胞共培養システムの構築2009
- Author(s)
  木村啓志, 中山秀謹, 山本貴富喜, 酒井康行, 藤井輝夫
- Journal Title
  
  電気学会論文誌E 26
  
  Pages: 151-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034013
[Journal Article] Low O2 metabolism of Hep G2 cells cultured at high cell density in a 3D microstructured scaffolds2009
- Author(s)
  C.Provin, K.Takano, T.Yoshida, Y.Sakai, T.Fujii, R.Shirakashi
- Journal Title
  
  Biomedical Microdevices 11
  
  Pages: 485-494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034013
[Journal Article] Stable immobilization of rat hepatocytes as hemispheroids onto collagenconjugated polydimethylsiloxane (PDMS) surfaces : importance of direct oxygenation through PDMS for both formation and function2008
- Author(s)
  M. Nishikawa, T. Yamamoto, N. Kojima, K. Komori, T. Fujii, and Y. Sakai
- Journal Title
  
  Biotechnology and Bioengineering 99
  
  Pages: 1472-1481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034013
[Journal Article] A method for the design of 3D scaffolds for high-density cell attachment and determination of optimum perfusion culture conditions2008
- Author(s)
  C. Provin, K. Takano, Y. Sakai, T. Fujii R. Shirakashi
- Journal Title
  
  J.Biomech. 41(7)
  
  Pages: 1436-1449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] Soluble factor-dependent in vitro growth and maturation of rat fetal liver cells in a three-dimensional culture system, T2008
- Author(s)
  S. Hanada, N. Kojima, Y. Sakai
- Journal Title
  
  Tissue Eng. 14(1)
  
  Pages: 149-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] 組織工学的手法を用いた肝組織再構築に関する研究の現状と課題2008
- Author(s)
  花田三四郎, 酒井康行
- Journal Title
  
  生産研究 60
  
  Pages: 147-151
- NAID
  110006936136
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] An integrated microfluidic system for long-term perfusion culture and on-line monitoring of intestinal tissue models2008
- Author(s)
  H. Kimura, T. Yamamoto, H. Sakai, Y. Sakai, T. Fujii
- Journal Title
  
  Lab on-a-Chip 8
  
  Pages: 741-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034013
[Journal Article] A method for the design of 3D scaffolds for high-density cell attachment and determination of optimum perfusion culture conditions2008
- Author(s)
  C. Provin, K. Takano, Y. Sakai, T. Fujii, R. Shirakashi
- Journal Title
  
  Journal of Biomechanics 41
  
  Pages: 1436-1449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034013
[Journal Article] Enhanced maintenance and functions of rat hepatocytes induced by combination of on-site oxygenation and coculture with fibroblasts2008
- Author(s)
  M. Nishikawa, N. Kojima, K. Komori, T. Yamamoto, T. Fujii, Y. Sakai
- Journal Title
  
  J. Biotechnol. 133
  
  Pages: 1472-1481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18048012
[Journal Article] Soluble factor-dependent in vitro growth and maturation of rat fetal liver cells in a three-dimensional culture system2008
- Author(s)
  S.Hanada, N.Kojima, Y.Sakai
- Journal Title
  
  Tissue Engineering Part A 14
  
  Pages: 149-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] 組織工学的手法を用いた肝組織再構築に関する研究の現状と課題2008
- Author(s)
  花田三四郎・酒井康行
- Journal Title
  
  生産研究 60
  
  Pages: 147-151
- NAID
  110006936136
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] Avidin-biotin binding-based cell seeding and perfusion culture of liver-derived cells in a porous scaffold with a three-dimensional interconnected flow-channel network2007
- Author(s)
  Huang H., Oizumi S., Kojima N Niino T., Sakai Y.
- Journal Title
  
  Biomat. 28
  
  Pages: 3815-3823
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] 高空孔率組織工学用担体の粉末焼結積層造形2007
- Author(s)
  新野俊樹, 成毛宏道, 大泉俊輔, 酒井康行, 黄紅雲
- Journal Title
  
  生産研究 59
  
  Pages: 492-499
- NAID
  110006936089
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Solid Freeform Fabrication of Tissue Engineering Scaffolds2007
- Author(s)
  Niino T., Sakai Y.
- Journal Title
  
  J. JSPE 73
  
  Pages: 528-532
- NAID
  110006285625
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] 生体組織工学用担体の積層造形技術2007
- Author(s)
  新野, 酒井
- Journal Title
  
  精密工学会誌 73
  
  Pages: 523-532
- NAID
  110006285625
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Development of a multi-compartment micro-cell culture device as a future on-chip human: fabrication of a three-compartment device and immobilization of rat mature adipocytes for the evaluation of chemical distributions2007
- Author(s)
  H. Nakayama, H. Kimura, K. Komori, T. Fujii, and Y. Sakai
- Journal Title
  
  J. Robotics Mechatr. 19
  
  Pages: 544-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18048012
[Journal Article] 高代謝速度臓器再構築を目的とした3次元担体の水溶性フィラを援用した粉末焼結積層造形2007
- Author(s)
  新野, 成毛, 大泉, 酒井, 黄
- Journal Title
  
  精密工学会誌 13
  
  Pages: 1246-1250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] 高代謝速度臓器再構築を目的とした3次元担体の水溶性フィラを援用した粉末焼結積層造形法-微細流路ネットワークが配置された生分解性ポリマ多孔質体の造形-2007
- Author(s)
  新野, 成毛, 大泉, 酒井, 黄
- Journal Title
  
  精密工学会誌 73
  
  Pages: 1246-1250
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Microfluidic perfusion culture of human hepatocytes2007
- Author(s)
  H. Kimura, M. Nishikawa, T. Yamamoto, Y. Sakai, and T. Fujii
- Journal Title
  
  J. Robotics Mechatr. 19
  
  Pages: 550-556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18048012
[Journal Article] Avidin-biotin binding-based cell seeding and perfusion culture of liver-derived cells in a porous scaffold with a three-dimensional interconnected flow-channel network2007
- Author(s)
  Huang H., Oizumi S., Kojima Nniino T., Sakai Y.
- Journal Title
  
  Biomat 28
  
  Pages: 3815-3823
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] 高代謝速度臓器再構築を目的とした3次元担体の水溶性フィラを援用した粉末焼結積層造形2007
- Author(s)
  新野, 成毛, 大泉, 酒井, 黄
- Journal Title
  
  精密工学会誌 13,11
  
  Pages: 1246-1250
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Feasibility of direct oxygenation of primary-cultured rat hepatocytes using polyethylene glycol decorated liposome-encapsulated hemoglobin (LEH)2007
- Author(s)
  Naruto H., Huang H., Nishikawa M., Kojima N, Mizuno A., Ohta K., Sakai Y.
- Journal Title
  
  J. Biosci. Bioeng 104
  
  Pages: 343-346
- NAID
  110006437019
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Fabrication of Three-dimensional Scaffolds for Regeneration of High-metabolic-rate Organs by Selective Laser Sintering Using Water Leachable Filler -Fabrication of Porous Bodies with Fine Flow Channel Network from Biodegradable Plastic-2007
- Author(s)
  Niino T., Naruke H., Oizumi S., Sakai Y., Huang H.
- Journal Title
  
  J. JSPE 73
  
  Pages: 1246-1250
- NAID
  110006440309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Enhanced functional maturation of fetal porcine hepatocytes in three-dimensional poly-L-lactic acid scaffolds: a culture condition suitable for engineered liver tissues in large-scale animal studies2006
- Author(s)
  Huang H., Hanada S., Kojima N, Sakai Y.
- Journal Title
  
  Cell Transplant 15
  
  Pages: 799-809
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Rapid hepatic cell attachment onto biodegradable polymer surfaces without toxicity using an avidin-biotin binding system2006
- Author(s)
  Nobuhiko Kojima, Tomoki Matsuo, Yasuyuki Sakai
- Journal Title
  
  Biomaterials 27・28
  
  Pages: 4904-4910
- Data Source
  KAKENHI-PROJECT-17650130
[Journal Article] 人工臓器への応用を目的とした種々の足場構造の物質輸送に関する基礎的研究2006
- Author(s)
  高野清, Christophe Provin, 酒井康行, 藤井輝夫, 白樫了
- Journal Title
  
  日本伝熱シンポジウム講演論文集 (In press)
- Data Source
  KAKENHI-PROJECT-16656068
[Journal Article] Fabrication of Microbioreactors with an Optimized Structure Designed for High Culture Density of Hepatocyte2006
- Author(s)
  Christophe Provin, Kiyoshi Takano, Ryo Shirakashi, Yasayuki Sakai, Teruo Fujii
- Journal Title
  
  Proceedings of International Conference on Microtechnologies in Medicine and Biology (In press)
- Data Source
  KAKENHI-PROJECT-16656068
[Journal Article] Enhanced functional maturation of fetal porcine hepatocytes in three-dimensional poly-L-lactic acid scaffolds : a culture condition suitable for engineered liver tissues in large-scale animal studies2006
- Author(s)
  Huang H., Hanada S., Kojima N, Sakai Y.
- Journal Title
  
  Cell Transplant 15
  
  Pages: 799-809
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] Enhanced Functional Maturation of Fetal Porcine Hepatocytes in Three-dimensional Poly-L-lactic Acid Scaffolds: A Culture Condition Suitable for Engineered Liver Tissues in Large-Scale Animal2006
- Author(s)
  Hongyun Huang, Sanshiro Hanada, Nobuhiko Kojima and Yasuyuki Sakai
- Journal Title
  
  Cell Transplantation 15
  
  Pages: 799-809
- Data Source
  KAKENHI-PROJECT-18360067
[Journal Article] ヒト体内動態把握を日指すin vitro複合培養システムの可能性2005
- Author(s)
  酒井康行, 藤井輝夫, 迫田章義
- Journal Title
  
  日本薬理学会誌 (印刷中)
- Data Source
  KAKENHI-PROJECT-15651015
[Journal Article] バイオアッセイの現状と課題2005
- Author(s)
  酒井康行
- Journal Title
  
  環境浄化技術 2005-4(2)
  
  Pages: 6-9
- Data Source
  KAKENHI-PROJECT-15651015
[Journal Article] In vitro血液胎盤関門モデルの作製と受動能動輸送評価2005
- Author(s)
  酒井康行, 渡辺信和, 高橋恒夫
- Journal Title
  
  生産研究 (印刷中)
- Data Source
  KAKENHI-PROJECT-15651015
[Journal Article] Efficacy of immunoadsorbent devices for maintaining hepatic function in ex vivo direct xenogeneic hemoperfusion.2004
- Author(s)
  Shindoh J, Naruse K, Sakai Y, Makuuchi M.
- Journal Title
  
  International Journal of Artificial Organs 27
  
  Pages: 294-302
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591299
[Journal Article] Efficacy of engineered liver tissue based on poly-L-lactic acid scaffolds and fetal mouse liver cells cultured with Oncostatin M, nicotinamide and dimethyl sulfoxide.2004
- Author(s)
  Jinlan J, Kojima N, Guo L, Naruse K, Makuuchi M, Miyajima A, Yan W, Sakai Y.
- Journal Title
  
  Tissue Engineering 10
  
  Pages: 1577-1586
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591299
[Journal Article] Efficacy of engineered liver tissue based on poly-L-lactic acid scaffolds and fetal mouse liver cells cultured with Oncostatin M, nicotinamide and dimethyl sulfoxide2004
- Author(s)
  Jinlan J, Kojima N, Guo L, Naruse K, Makuuchi M, Miyajima A, Yan W, Sakai Y.
- Journal Title
  
  Tissue Engineering 10
  
  Pages: 1577-1586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591299
[Journal Article] Transplantation of a fetal liver cell-loaded hyaluronic acid sponge onto the mesentery recovers a Wilson's disease model rat
- Author(s)
  T. Katsuda, T. Teratani, T. Ochiya, Y. Sakai
- Journal Title
  
  J.Biochem (in press)
- NAID
  10027878100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] Direct oxygen supply with poly dimethylsiloxane (PDMS) membranes induces a spontaneous organization of thick heterogeneous liver tissues from rat fetal liver cells in vitro
- Author(s)
  M. Hamon, S. Hanada, T. Fujii, Y. Sakai
- Journal Title
  
  Cell Transplant (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19360371
[Journal Article] Laser Sintering Freeform Fabrication of Highly Porous Tissue Engineering Scaffolds
- Author(s)
  Niino T., Naruke H., Oizumi S., Sakai Y., Huang H.
- Journal Title
  
  SEISAN-KENKYU 59
  
  Pages: 492-499
- NAID
  110006936089
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Patent] 細胞組織の構築方法および装置2006
- Inventor(s)
  酒井,康行, 小島伸彦, 松尾朋樹
- Industrial Property Rights Holder
  酒井,康行, 小島伸彦, 松尾朋樹
- Industrial Property Number
  2006-013519
- Filing Date
  2006-01-23
- Data Source
  KAKENHI-PROJECT-17650130
[Presentation] 精緻な腎オルガノイド構築を目指した腎ストローマ前駆細胞培養法2023
- Author(s)
  小林拓真，チャン　シャオミン，ヤナガワ　ノリモト，西川昌輝，酒井康行
- Organizer
  人工臓器学会
- Data Source
  KAKENHI-PROJECT-20H04499
[Presentation] 腎ストローマ前駆細胞培養法の開発2023
- Author(s)
  28.Kobayashi, T.; Chang, HM.; Danoy, M.; Nishikawa, M.; Sakai, Y.; Yanagawa, N
- Organizer
  The Japanese Society for Regenerative Medicin
- Data Source
  KAKENHI-PROJECT-20H04499
[Presentation] 生体外での腎組織への血管新生2023
- Author(s)
  30.Shioda, H.; Myasnikova, D.; Takeuchi, S.; Hanada, S.; Danoy, M.; Nishikawa, M.; Sakai, Y.
- Organizer
  The Japanese Society for Regenerative Medicine
- Data Source
  KAKENHI-PROJECT-20H04499
[Presentation] 生体外での腎組織への血管新生2023
- Author(s)
  塩田拓輝，酒井康行，西川昌輝，竹内昌治，Dina Myasnikova，花田三四郎
- Organizer
  人工臓器学会
- Data Source
  KAKENHI-PROJECT-20H04499
[Presentation] Japanese MPS project I/II and a developed new MPS device with micro-stirrer-based on-chip perfusion and direct oxygenation2022
- Author(s)
  Yasuyuki Sakai, Dhimas A. Kurniawan, Mathieu Danoy, Hiroshi Kimura, Masaki Nishikawa
- Organizer
  5th Symposium on Organoids and Organs-on-Chips
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] A transcriptomic study on the influence of the stimulation by a microfluidic environment for the induction of zonation-like patterns in carboxypeptidase M-positive human pluripotent stem cells-derived liver progenitor cells2022
- Author(s)
  Danoy M, Poulain S, Scheidecker B, Kim S.H, Kido T, Miyajima A, Sakai Y, Leclerc E
- Organizer
  WCB, World congress of biomechanics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K25188
[Presentation] MPS STATUS UPDATE Japan2022
- Author(s)
  Yasuyuki Sakai
- Organizer
  MPS World Summit 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] Functional enhancements and crosstalk of liver-small intestine in a 　micro-stirrer-based on-chip perfusion MPS with direct oxygenation2022
- Author(s)
  Dhimas Agung Kurniawan, Kousuke Inamura, Danoy Mathieu, Sohei Funaoka, 　Daichi Aihara, Takeshi Sakura, Takumi Kawanishi, Hiroshi Arakawa, Yukio Kato, Masaki Nishikawa, Hiroshi Kimura and Yasuyuki Sakai
- Organizer
  MPS World Summit 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] 生体模倣システム(MPS)開発研究の最新動向と実用化2022
- Author(s)
  酒井康行
- Organizer
  第96回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] Effect of direct oxygenation and coculture on primary hepatocytes & intestine 　epithelial cells cultured in stirrer-based microphysiological system (MPS) device2022
- Author(s)
  Dhimas Kurniawan, Kousuke Inamura, Mathieu Danoy, Sylvia Leo, 　Mutsumi Inamatsu, Sohei Funaoka, Daichi Aihara, Takeshi Sakura, Takumi Kawanishi, Hiroshi Arakawa, Yukio Kato, Masaki Nishikawa, Nobuaki Shiraki, Shoen Kume, Hiroshi Kimura, Yasuyuki Sakai
- Organizer
  Tissue Engineering and Regenerative Medicine International Society; Asia-Pacific Conference 2022 (TERMIS AP 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] Cell Culture Multimodal Electrical Analyses with Thin-Film-Transistor Sensing Platform2022
- Author(s)
  Agnes Tixier-Mita, Ihida Satoshi, Dongchen Zhu, Pierre-Marie Faure, Yasuyuki Sakai, Timothee Levi, and Hiroshi Toshiyoshi
- Organizer
  第128回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K18869
[Presentation] オンチップ灌流・直接酸素供給マイクロフィジオロジカルシステムを用いた in vitro における肝－小腸薬物代謝関連クロストークの解明2022
- Author(s)
  Dhimas Kurniawan, 稲村恒亮, Mathieu Danoy, Sylvia Leo, 稲松睦, 舩岡創平, 相原大知, 佐倉武司, 荒川大, 加藤将夫, 松木智昭, 江刺家勝弘, 西川昌輝, 白木伸明, 粂昭苑, 木村啓志, 酒井康行
- Organizer
  第34回日本動物実験代替法学会
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] 学術研究のための動物実験代替法の例と今後2022
- Author(s)
  酒井康行
- Organizer
  化学とマイクロ・ナノシステム学会第45回研究会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] Enhanced metabolic functions of hepatocytes with aerobic respiration enabled by a new oxygen-permeable plate2022
- Author(s)
  Yasuyuki Sakai, Hiroyasu Ito, Fumiya Tokito, Mathieu Danoy, Takumi Kawanishi, Hiroshi Arakawa, Yukio Kato, Tomoaki Matsugi, Katsuhiro Esashika, Hiroshi Miyasako, Toru Sumita, Masaki Nishikawa
- Organizer
  The 2022 European Congress on Alternatives to Animal Testing (EUSAAT 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] 広義のマイクロフィジオロジカルシステムへの期待をインビトロ系の格段の活用の契機に！2022
- Author(s)
  酒井康行
- Organizer
  第29回HAB研究機構学術年会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] 臓器連関の観測・解析を可能とするマイクロフィジオロジカルシステム(MPS)2022
- Author(s)
  酒井康行
- Organizer
  第60回日本人工臓器学会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] In-vitro Electrophysiology Evaluation of Beta-cells based on Thin Film Transistor Microelectrode Array2022
- Author(s)
  Dongchen Zhu, Anne-Claire Eiler, Satoshi Ihida, Yasuyuki Sakai, Hiroshi Toshiyoshi, Agnes Tixier-Mita, Kikuo Komori
- Organizer
  日本動物実験代替法学会第35回大会
- Data Source
  KAKENHI-PROJECT-21K18869
[Presentation] Development of microphysiological systems for the liver-kidney axis2022
- Author(s)
  10.Nishikawa, M.; Ito, H.; Inamura, K.; Scheidecker, B.; Danoy, M.; Arakawa, H.; Kato, Y.; Esashika, K.; Miyasako, H.; Sakai, Y.:
- Organizer
  The Japanese Society for Regenerative Medicine
- Data Source
  KAKENHI-PROJECT-20H04499
[Presentation] 粒子トラッキングに基づくiPS細胞の浮遊懸濁培養の運転条件最適化2022
- Author(s)
  堀口一樹，長手武尊，谷岡虹，長谷川慶，酒井康行，境慎司
- Organizer
  第22回再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K23144
[Presentation] マイクロフィジオロジカルシステム(MPS)を用いた人体応答評価のために2021
- Author(s)
  酒井康行
- Organizer
  第34回日本動物細胞工学会2021年度大会
- Invited
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] Current status of MPS development and its international extension2021
- Author(s)
  Y. Sakai
- Organizer
  18th DIA Japan Annual Meeting
- Invited
- Data Source
  KAKENHI-PLANNED-20H05745
[Presentation] Direct implantation of β cell aggregates using a hydrogel microwell device2020
- Author(s)
  Tulakarnwong Sarun・Inagaki F Natsuko・Oki Yuichiro・Ohta Seiichi・Shinohara Marie・Sakai Yasuyuki・Ito Taichi
- Organizer
  化学工学会第85年会
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] 酸素透過性多孔質担体を用いた膵島様組織培養2019
- Author(s)
  時任文弥, 篠原満利恵, 丸山優史, 酒井康行, 大竹勝人
- Organizer
  化学工学会第84年会
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Cost-effective differentiation of human iPS cells to pancreatic β-cells based on aggregate suspension culture with dialysis operations2019
- Author(s)
  H. Choi, M. Shinohara, Y. Sakai
- Organizer
  International Society for Stem Cell Research 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Improvement of high-density human induced pluripotent stem cell expansion in dynamic suspension culture system through small multicompartment dialysis device2019
- Author(s)
  F. G. Torizal, I. Horiguchi, Y. Sakai
- Organizer
  The 14th Asian Congress on Biotechnology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] High-density dynamic suspension culture system of human induced pluripotent stem cells in miniaturized multicompartment dialysis device2019
- Author(s)
  F. G. Torizal, I. Horiguchi, Y. Sakai
- Organizer
  International Society for Stem Cell Research 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] 再生膵島組織の血管導入移植用」ハイドロゲルデバイスの開発2019
- Author(s)
  池田俊介・稲垣奈津子・稲垣冬樹・國土典宏・篠原満利恵・酒井康行・太田誠一・伊藤大知
- Organizer
  化学工学会　第84年会
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Development of gelatin methacrylate and hydroxyethyl methacrylate hydrogel microwells for β cell implantation2019
- Author(s)
  Sarun Tulakarnwong・Ikeda Shunsuke・Oki Yuichiro・Ohta Seiichi・Shinohara Marie・Sakai Yasuyuki・Ito Taichi
- Organizer
  第57回日本人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Development of hydrogel microwells via photo-crosslinking of gelatin methacrylate and hydroxyethyl methacrylate for β cell spheroid formation dissemination of gastric cancer2019
- Author(s)
  Tulakarnwong Sarun・Ikeda Shunsuke・Ohta Seiichi・Shinohara Marie・Sakai Yasuyuki・Ito Taichi
- Organizer
  第19回生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Toward efficient production of organoids or cell aggregates― How to use biological autonomous capability?2019
- Author(s)
  Yasuyuki Sakai
- Organizer
  International Workshop on Engineering and Manufacture of Living Systems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Preparation of micro-sized perfluorocarbon-based emulsions and particles as oxygen carriers using SPG membrane emulsification2018
- Author(s)
  傅暁廷・太田誠一・上平正道・酒井康行・伊藤大知
- Organizer
  膜シンポジウム2018
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Toward efficient culture systems for hiPS cells2018
- Author(s)
  Yasuyuki SAKAI
- Organizer
  iLite-Hepatinov LIMMS workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Oxygen transfer-based design of 3D scaffolds for large metabolic tissues:2018
- Author(s)
  Yasuyuki SAKAI
- Organizer
  The 5th International Conference on Additive Manufacturing and Bio-Manufacturing
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] 代謝組織育成のための光架橋ハイドロゲルを用いたin vivo血流灌流デバイスの開発2018
- Author(s)
  池田俊介・太田誠一・稲垣冬樹・國土典宏・篠原満利恵・酒井康行・伊藤大知
- Organizer
  第56回日本人工臓器学会
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Hepatic Differentiation of Human Induced Pluripotent Stem Cells in Microfluidic Bioreactor: A New Tool for Translational Research2017
- Author(s)
  Myriam Lereau-Bernier, Bertrand-David Segard, Yannick Tauran, Mathieu Danoy, Keiichi Kimura, Marie Shinohara, Yasuyuki Sakai, Eric Leclerc
- Organizer
  細胞アッセイシンポジウム2017
- Place of Presentation
  東京大学
- Year and Date
  2017-01-31
- Data Source
  KAKENHI-PROJECT-16F16715
[Presentation] Prediction Of Nanoparticles Permeation Through Pulmonary Alveolous Using An In Vitro Co-Culture Model And A Numerical Simulation2017
- Author(s)
  植村文香，徐新穎，小森喜久夫，酒井康行
- Organizer
  化学工学会第82年会
- Place of Presentation
  芝浦工業大学
- Year and Date
  2017-03-06
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] Hepatic Differentiation of Human Induced Pluripotent Stem Cells in Microfluidic Bioreactor: A New Tool for Translational Research2017
- Author(s)
  Myriam Lereau-Bernier, Bertrand-David Segard, Yannick Tauran, Mathieu Danoy, Keiichi Kimura, Marie Shinohara, Yasuyuki Sakai, Eric Leclerc
- Organizer
  細胞アッセイ研究会シンポジウム
- Data Source
  KAKENHI-PROJECT-16F16715
[Presentation] 細胞アッセイ系の生理学性向上のための組織工学的アプローチ2017
- Author(s)
  酒井康行
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] 創薬応用を目指した肝細胞組織工学2017
- Author(s)
  酒井康行
- Organizer
  第69回日本生物工学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16F16715
[Presentation] Tissue engineering-based approaches to physiological-relevant cell-based assays2017
- Author(s)
  Yasuyuki Sakai
- Organizer
  The 3rd International Conference on Toxicity Testing Alternative & Translational Toxicology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16F16715
[Presentation] 再生組織育成のための光架橋ハイドロゲルを用いたin vivo血流灌流デバイスの開発2017
- Author(s)
  池田俊介・太田誠一・稲垣冬樹・國土典宏・酒井康行・伊藤大知
- Organizer
  化学工学会第83年会
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Hepatic Differentiation of Human iPS Cells in a Microfluidic Bioreactor: A New Tool for Translational Research2017
- Author(s)
  Myriam Lereau-Bernier, Mathieu Danoy, Marie Shinohara, Yasuyuki Sakai, Eric Leclerc
- Organizer
  第24回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-16F16715
[Presentation] Hepatic Differentiation of Human Induced Pluripotent Stem Cells in Microfluidic Bioreactor2016
- Author(s)
  Myriam Lereau-Bernier, Bertrand-David Segard, Yannick Tauran, Mathieu Danoy, Keiichi Kimura, Marie Shinohara, Yasuyuki Sakai, Eric Leclerc
- Organizer
  -Laboratory for Integrated Micro-Mechatronic Systems (LiMMS) workshop
- Place of Presentation
  東京大学
- Year and Date
  2016-12-12
- Data Source
  KAKENHI-PROJECT-16F16715
[Presentation] Design and generation of multi-scale 3D environments for liver tissue engineering2016
- Author(s)
  Y. Sakai
- Organizer
  Biomaterials International 2016
- Place of Presentation
  Howard Beach Resort, Kenting, Taiwan
- Year and Date
  2016-10-30
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] A Proliferation Switch of Fibroblasts in Alginate Microcapsules by in Situ Conjugation2016
- Author(s)
  Taichi Ito, Katsuhisa Kirita, Seiichi Ohta and Yasuyuki Sakai
- Organizer
  Biomaterials International 2016
- Place of Presentation
  Howard Beach Resort, Kenting, Taiwan
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] 階層的共培養肺胞モデルと数理モデルとを用いた経肺吸収予測2016
- Author(s)
  植村文香，徐新穎，小森喜久夫，酒井康行
- Organizer
  第29回日本動物実験代替法学会
- Place of Presentation
  九州大学
- Year and Date
  2016-11-16
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] 物質交換性に富む新たな組織構築用微小担体三次元造形2016
- Author(s)
  酒井康行, Stephanie SUTOKO, Pang Yuan, 堀本洋平, 安斎正博, 新野俊樹
- Organizer
  第54回日本人工臓器学会大会
- Place of Presentation
  米子, 米子コンベンションセンター BIG SHIP
- Year and Date
  2016-11-23
- Data Source
  KAKENHI-PROJECT-16H02419
[Presentation] Formation of in Vitro Co-culture Model of Pulmonary Alveolus Using human epithelial cell line A549, human monocytic cell line THP-1, and human umbilical vein cells HUVEC for Prediction Study of Nanoparticle Permeation2015
- Author(s)
  Xinying Xu, Ayaka Uemura, Kikuo Komori, Yasuyuki Sakai
- Organizer
  第28回日本動物代替法学会
- Place of Presentation
  神奈川県横浜市・ワークビア横浜
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] 生理学的培養組織モデル，Body/Organ on-a-Chip，定量的in vitro-in vivo外挿2015
- Author(s)
  酒井康行
- Organizer
  CBI学会2015年大会
- Place of Presentation
  東京都江戸川区・タワーホール船堀
- Year and Date
  2015-10-27
- Invited
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] Liver cord reconstruction in microfluidic device for drug screening by bile recovery : 1st steps2015
- Author(s)
  Perry, G., Xiao, W., Provin, C., Shinohara, M., Fujii, T. and Sakai, Y
- Organizer
  Symposium on New Technology for Cell-Based Drug Assay
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2015-01-13
- Data Source
  KAKENHI-PROJECT-13F03713
[Presentation] Establishment of a multicellular 3D liver model by co-culturing rat hepatocytes with TMNK-1 based on gas-permeable membranes for drug screening2015
- Author(s)
  Xiao, W., Perry, G., Komori, K. and Sakai, Y
- Organizer
  Symposium on New Technology for Cell-Based Drug Assay
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2015-01-13
- Data Source
  KAKENHI-PROJECT-13F03713
[Presentation] ボトムアップとトップダウンを融合する大型組織構築の方法論2014
- Author(s)
  酒井康行，厖媛，Stephanie L. U. SUTOKO，堀本洋平，安斎正博，新野俊樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] 細胞・組織培養と生理学的酸素供給2014
- Author(s)
  酒井康行
- Organizer
  第12回ガンとハイポキシア研究会
- Place of Presentation
  佐賀
- Year and Date
  2014-11-21
- Invited
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] On-chip absorption and metabolism model for pharmacokinetic studies2013
- Author(s)
  H. Kimura, T. Ikeda, Y. Sakai, T. Fujii
- Organizer
  MicroTAS2013
- Place of Presentation
  Freiburg, German
- Data Source
  KAKENHI-PROJECT-24710141
[Presentation] SPG膜乳化法を用いたヘモグロビン／アルブミン架橋型人工酸素運搬体の開発2013
- Author(s)
  Yao-Tong Lai・太田誠一・佐藤真優・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  第20回血液代替物学会
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] On-chip absorption and metabolism model for pharmacokinetic studies2013
- Author(s)
  H. Kimura, T. Ikeda, Y. Sakai, T. Fujii
- Organizer
  μTAS2013
- Place of Presentation
  German
- Data Source
  KAKENHI-PROJECT-24710141
[Presentation] Preparation of a novel hemoglobin-based oxygen carrier by the Shirasu porous glass membrane emulsification technique2013
- Author(s)
  Yao-Tong Lai, SeiichiOhta, Kazuki A kamatsu, Shinichi Nakao, Yasuyuki Sakai, Taichi Ito
- Organizer
  第51回日本人工臓器学会大会/第5回国際人工臓器学術大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] Microfabrication and chemical Engineering in organization of liver tissues for various applications2013
- Author(s)
  Yasuyuki Sakai
- Organizer
  Grand Challenge for Integration of Stem Cell, Nanomaterials and Biomanufacturing - Looking for Synergy” (SCNB2013)
- Place of Presentation
  上海
- Invited
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] ヘモグロビンを用いたSPG膜乳化法による新規人工酸素運搬体の開発2012
- Author(s)
  Yao-Tong Lai・佐藤真優・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台国際センター、宮城
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Development of hemoglobin-based oxygen carriers via SPG membrane emulsification technique2012
- Author(s)
  Yao-Tong Lai, Mayu Sato, Kazuki Akamatsu, Shin-ichi Nakao, Yasuyuki Sakai, Taichi Ito
- Organizer
  日本膜学会第34年会
- Place of Presentation
  早稲田大学西早稲田キャンパス 63 号館
- Year and Date
  2012-05-09
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Micro-technologies and chemical engineering for organization of liver tissue2012
- Author(s)
  Y. Sakai
- Organizer
  6th International Conference on Bioengineering and Nanotechnology
- Place of Presentation
  Berkeley, USA
- Invited
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] ヘモグロビンを用いたSPG膜乳化法による新規人工酸素運搬体の開発2012
- Author(s)
  Yao-TongLai・佐藤真優・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  日本バイオマテリアル学会シンポジウム2012
- Place of Presentation
  仙台国際センター宮城
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Self-secreted factors, oxygen and 3D culture in stem/progenitor cell-based tissue engineering ― mES/iPS, liver and pancreatic b-cells ―2012
- Author(s)
  Y. Sakai
- Organizer
  1st Joint Symposium 2012 on Bridging Cancer Nonotechnology, The University of Texas MD Anderson Cancer Center & University of Tokyo
- Place of Presentation
  Houston, USA
- Invited
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] Control of Culture Environment for Differentiation of Pluripotent Stem Cells2012
- Author(s)
  J. Kawada, S. Kaneda, H. Kimura, H. Akutsu, Y. Sakai, T. Fujii
- Organizer
  Microfluidics for Tissue and Cell Applications (JST CREST/SICP/ERATO) Joint Symposium
- Place of Presentation
  IIS University of Tokyo
- Year and Date
  2012-10-05
- Data Source
  KAKENHI-PROJECT-24710141
[Presentation] 酸素透過性材料を用いた厚いシート状肝・膵島組織の作成2012
- Author(s)
  酒井康行、Fanny Evenou、Morgan Hamon、篠原満利恵、小森喜久夫、藤井輝夫
- Organizer
  日本再生医療学会第11回総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] On-Chip Absorption and Metabolism Model for Pharmacokinetic Studies2012
- Author(s)
  H. Kimura, T. Ikeda, Y. Sakai, T. Fujii
- Organizer
  IEEE EMBS Micro and Nanotechnology in Medicine Conference
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24710141
[Presentation] Preparation of uniformly-sized microspheres of hemoglobin and albumin as oxygen carriers by the Shirasu porous glass membrane emulsification technique2012
- Author(s)
  Yao-Tong Lai, Mayu Sato, Yukimitsu Suzuki, Kazuki Akamatsu, Shin-ichi Nakao, Sakai Yasuyuki, Taichi Ito
- Organizer
  Symposium on New Technology for Cell-based Drug Assay, Ichijo Hall, Yayoi Auditorium
- Place of Presentation
  The University of Tokyo
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] SPG膜乳化法によるヘモグロビンベース新規人工酸素運搬体の開発2012
- Author(s)
  LaiYao-Tong、佐藤真優・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2012-06-14
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Preparation of monodispersed poly(Methacryloxypropyl tris(trimethylsiloxy) silane) microspheres via SPG membrane emulsification technique2012
- Author(s)
  Yao-Tong Lai, Kazuki Akamatsu, Shin-ichi Nakao, Yasuyuki Sakai, TaichiIto
- Organizer
  化学工学会第 44回秋季大会
- Place of Presentation
  東北大学川内北キャンパス宮城
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] New 3D scaffold consisting of assembled subunits as culture chambers and an interconnected flow-channel network for liver tissue engineering2012
- Author(s)
  Yuan PANG, Yohei HORIMOTO, kentaro HARA, Yutaro ITAGAKI, Toshiki NIINO, Yasuyuki SAKAI
- Organizer
  International Conference on Biofabrication 2012
- Place of Presentation
  Manchester, UK
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] Preparation of monodispersed poly(Methacryloxypropyl tris(trimethylsiloxylsiloxy) silane) microspheres via SPG membrane emulsification technique2012
- Author(s)
  Yao-Tong Lai, Kazuki Akamatsu, Shin-ichi Nakao, Yasuyuki Sakai, Taichi Ito
- Organizer
  化学工学会第44回秋季大会
- Place of Presentation
  東北大学川内北キャンパス、宮城
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Scaffolds having flow channels, oxygen carriers and oxygen-permeable membranes2011
- Author(s)
  Yasuyuki SAKAI, Teruo FUJII, Toshiki NIINO
- Organizer
  HAAISHAPD 2011 Annual Scientific Meeting
- Place of Presentation
  シドニー,オーストラリア(招待講演)
- Year and Date
  2011-11-01
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] 胆汁輸送機構を配備した肝暇様組織のin vitro再構築2011
- Author(s)
  勝田毅, 小島伸彦, 落谷孝広, 酒井康行
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-22650108
[Presentation] On-chip Absorption and Metabolism Model for Evaluation of Pharmacokinetics2011
- Author(s)
  T.Ikeda, J.Kawada, H.Kimura, Y.Sakai, T.Fujii
- Organizer
  Biofabrication 2011
- Place of Presentation
  Toyama international conference center
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-22710120
[Presentation] 膜乳化法を用いた人工赤血球の開発2011
- Author(s)
  佐藤真優・鈴木幸光・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  膜シンポジウム2011
- Place of Presentation
  健康文化村　カルチャーリゾートフェストーネ（沖縄県）
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Chemical engineering-based multi-scale optimization of 3D cellular organization and oxygen supply2011
- Author(s)
  Y.Sakai
- Organizer
  2011 MRS Fall Meeting & Exhibition
- Place of Presentation
  ボストン,米国(招待講演)
- Year and Date
  2011-11-30
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] 胆管ネットワーク構造を配備した肝臓様組織のin vitro再構築2011
- Author(s)
  Katsuda T, Kojima N, Ochiya T, Sakai Y
- Organizer
  第84回生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22650108
[Presentation] 胆汁輸送機構を配備した肝臓様組織のin vitro再構築2011
- Author(s)
  勝田毅、小島伸彦、落谷孝広、酒井康行
- Organizer
  第10回日本再生医療学会
- Place of Presentation
  東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-22650108
[Presentation] In vitro reconstruction of a liver-liketissue possessing a bile transport system,T2011
- Author(s)
  Katsuda T,Kojima N,Ochiya T,Sakai Y,
- Organizer
  ERMIS-EU meeting
- Place of Presentation
  Granada,Spain
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22650108
[Presentation] 膜乳化法を用いた人工赤血球の開発2011
- Author(s)
  佐藤真優・鈴木幸光・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  膜シンポジウム2011
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] 薬物動態評価のためのオンチップ吸収代謝モデル2011
- Author(s)
  池田崇, 木村啓志, 酒井康行, 藤井輝夫
- Organizer
  SI2011
- Place of Presentation
  京都大学吉田キャンパス
- Year and Date
  2011-12-24
- Data Source
  KAKENHI-PROJECT-22710120
[Presentation] 胆管ネットワーク構造を配備した肝臓様組織のin vitro再構築2011
- Author(s)
  Katsuda T,Kojima N,Ochiya T,Sakai Y
- Organizer
  第84回生化学会大会,
- Place of Presentation
  京都.
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22650108
[Presentation] In vitro reconstruction of a liver-like tissue possessing a bile transport system2011
- Author(s)
  Katsuda T, Kojima N, Ochiya T, Sakai Y
- Organizer
  TERMIS-EU meeting
- Place of Presentation
  Granada, Spain
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22650108
[Presentation] 化学物質の効果毒性評価のための肝組織構築2010
- Author(s)
  酒井康行, 亀田一平, 鈴木宏明, Fanny EVENOU, Morgan HAMON, 小森喜久夫, 松井等, 小島信彦, 山本尚子, 津田行子, 関島勝, 藤井輝夫, 竹内昌二
- Organizer
  第9回再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-19
- Data Source
  KAKENHI-PROJECT-20034013
[Presentation] Microfluidic device with Integrated Electrochemical Sensor for Cell-based Assay in Toxicology2010
- Author(s)
  H.Kimura, H.Takeyama, K.Komori, Y.Sakai, T.Fujii
- Organizer
  Conference Proceedings of International Symposium on Microchemistry and Microsystems (ISMM)
- Place of Presentation
  Kowloon, Hong Kong 中国
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22710120
[Presentation] Importance of oxygen supply in liver tissue engineering : Scaffolds having flow channels, oxygen carriers and oxygen-permeable membranes2010
- Author(s)
  Yasuyuki Sakai, Toshiki Niino
- Organizer
  BIT Life Sciences' 3rd Annual Congress of Regenerative Medicine & Stem Cell-2010
- Place of Presentation
  中国,上海
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] 肝細胞培養のための生体内環境を模倣したマイクロ流体デバイス2010
- Author(s)
  中尾洋祐, 川田治良, 木村啓志, 酒井康行, 藤井輝夫
- Organizer
  第21回化学とマイクロ・ナノシステム研究会
- Place of Presentation
  東京大学本郷キャンパス
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-22710120
[Presentation] 高代謝形臓器再構築のための担体デザインと三次元造形(招待講演)2010
- Author(s)
  酒井康行, 新野俊樹
- Organizer
  機械学会第22回バイオエンジニアリング講演会
- Place of Presentation
  岡山
- Year and Date
  2010-01-10
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] Microfluidic device with Integrated Electrochemical Sensor for Cell-based Assay in Toxicology2010
- Author(s)
  H. Kimura、H. Takeyama、K. Komori Y. Sakai、T. Fujii
- Organizer
  International Symposium on Microchemistry and Microsystems(ISMM)
- Place of Presentation
  Kowloon、Hong Kong
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22710120
[Presentation] 肝細胞索構造を模倣したマイクロ流体デバイス2010
- Author(s)
  中尾洋祐, 川田治良, 木村啓志, 酒井康行, 藤井輝夫
- Organizer
  第11回計測自動制御学会システムインテグレーション部門講演会(SI2010)
- Place of Presentation
  東北大学川内キャンパス
- Year and Date
  2010-12-25
- Data Source
  KAKENHI-PROJECT-22710120
[Presentation] 各種スケールの2D・3D組織再構築と工学的方法論, 招待講演2009
- Author(s)
  酒井康行, 山口哲志, 小森喜久夫, 新海政重, 新野俊樹, 藤井輝夫, 長棟輝行, 牛田多加志
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] マウスES細胞からの効率的な肝細胞分化を目指した培養環境制御の導入2009
- Author(s)
  勝田毅, 寺谷工, 落谷孝広, 酒井康行
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形(口頭発表)
- Year and Date
  2009-06-15
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] 酸素分圧の段階的制御によるマウスES細胞からの肝細胞分化誘導2009
- Author(s)
  勝田毅, 寺谷工, 落谷孝広, 酒井康行
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京(口頭発表)
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] 酸素分圧の段階的制御によるマウスES細胞からの肝細胞分化誘導2009
- Author(s)
  勝田毅, 寺谷工, 落谷孝広, 酒井康行
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] 大型肝組織再構築のための担体デザイン・三次元造形・前駆細胞育成, 招待講演2008
- Author(s)
  酒井康行, 黄紅雲, 大泉俊輔, 水野篤志, 太田勝次, 小島伸彦, 新野俊樹
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-21
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] 胎生後期ラット胎児肝細胞の三次元培養と液性因子による成熟化の検討2008
- Author(s)
  花田三四郎, 酒井康行
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-03-13
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] 肝細胞培養における工学的外部環境の寄与-三次元化・酸素供給-, 招待講演2008
- Author(s)
  酒井康行, 黄紅雲, 花田三四郎, 西川昌輝, 小森喜久夫, 小島伸彦, 山本貴富喜,藤井輝夫
- Organizer
  第15回肝細胞研究会
- Place of Presentation
  静岡
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] マウスES細胞からの肝細胞分化誘導のための新規培養系2008
- Author(s)
  高橋亨, 寺谷工, 西川昌輝, 藤井輝夫, 落谷孝広, 酒井康行
- Organizer
  化学工学会第73回大会
- Place of Presentation
  静岡(口頭発表)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] Fetal rat liver cell cultures : maintenance of liver function and formation of thick tissue induced by the enhancement of oxygen supply2008
- Author(s)
  M Hamon, T Fujii, Y. Sakai
- Organizer
  Tissue Engineering and Regenerative Medicine International Society, Asia-Pacific Chapter Meeting 2008
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2008-09-15
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] Contributions of Nano- and Micro-Technologies to Liver Tissue Engineering, 招待講演2008
- Author(s)
  Y. Sakai
- Organizer
  CNBI-CNSI 合同ナノテクシンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-08-25
- Data Source
  KAKENHI-PROJECT-19360371
[Presentation] 化学物質体内動態評価のための複合培養チップの開発2008
- Author(s)
  中山秀謹、木村啓志、小森喜久夫、藤井輝夫、酒井康行
- Organizer
  日本動物実験代替法学会第21回大会
- Place of Presentation
  埼玉市
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-20034013
[Presentation] Development of a disposable three-compartment micro-cell culture device for toxi cokinetic study in humans and its preliminary evaluation2007
- Author(s)
  H. Nakayama, K. Kimura, K. Komori, T. Fujii, Y. Sakai
- Organizer
  6th World Congress on Alternatives & Animal Use in the Life Sciences
- Place of Presentation
  東京
- Year and Date
  2007-08-23
- Data Source
  KAKENHI-PROJECT-18048012
[Presentation] Laser Sintering Fabrication of Highly Porous Models Utilizing Water Leachable Filler -Experimental Investigation into Process Parameters-2007
- Author(s)
  Niino T., Sakai Y., Hongyun H., Naruke H.
- Organizer
  Solid Freeform Fabrication Symposium
- Place of Presentation
  TX, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Presentation] SLS Fabrication of Highly Porous Model Including Fine Flow Channel Network Aiming at Regeneration of Highly Metabolic Organs2006
- Author(s)
  Niino T., Sakai Y., Huang H., Naruke H.
- Organizer
  Solid Freeform Fabrication Symposium
- Place of Presentation
  TX, USA
- Year and Date
  2006-08-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Presentation] A porous perfusion bioreactor that possesses microchannels: its fabrication by selective laser sintering and preliminary evaluation of culture of human hepatoma Hep G2 cells2006
- Author(s)
  Huang H., Kojima N, Naruke H, Oizumi S, Niino T, Sakai Y.
- Organizer
  AIChE
- Place of Presentation
  CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Presentation] Use of Liposome Encapsulated Hemoglobin (Leh) as an Oxygen Carrier to Cultured Cells2006
- Author(s)
  Sakai Y, Huang H, Naruto H, Nishikawa M, Kojima N, MizunoA, Ohta K
- Organizer
  AIChE
- Place of Presentation
  CA, USA
- Year and Date
  2006-11-13
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Presentation] A porous perfusion bioreactor that possesses microchannels : its fabrication by selective laser sintering and preliminary evaluation of culture of human hepatoma Hep G2 cells2006
- Author(s)
  Huang H., Kojima N, Naruke H, Oizumi S, Niino T, Sakai Y.
- Organizer
  AIChE
- Place of Presentation
  CA, USA
- Year and Date
  2006-11-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18360067
[Presentation] 薬効・毒性評価野ための生理学的培養組織モデル
- Author(s)
  酒井康行，竹内昌治，藤井輝夫
- Organizer
  第66回日本生物工学大会
- Place of Presentation
  札幌
- Year and Date
  2014-09-09 – 2014-09-11
- Invited
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] ヘモグロビン／アルブミンマイクロスフィア型人工酸素運搬体の細胞取り込みと生体適合性に与えるサイズの影響
- Author(s)
  Yao-Tong Lai・太田誠一・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  第21回血液代替物学会
- Place of Presentation
  東京
- Year and Date
  2014-12-08 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] SPG膜乳化型酸素運搬体による肝細胞への酸素供給の検討
- Author(s)
  Yao-Tong Lai・太田誠一・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  第14回　日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2015-03-29 – 2015-03-31
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] ナノ粒子の毒性評価のためのラット初代培養肺胞組織モデルの開発
- Author(s)
  原納弘大, 岩沢こころ, 小笠原理恵, 諏訪部章, 酒井康行
- Organizer
  化学工学会　第80年会
- Place of Presentation
  東京
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26550046
[Presentation] Design and fabrication of scalable three‐dimensional scaffold for in vitro liver tissue engineering
- Author(s)
  Yuan PANG, Yohei HORIMOTO, Stephanie Sutoko, Toshiki NIINO, Yasuyuki SAKAI
- Organizer
  International Conference on Biofabrication 2014
- Place of Presentation
  Pohang, Korea
- Year and Date
  2014-09-28 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] Design, fabrication and performance evaluation in packed-bed perfusion culture of liver cells
- Author(s)
  S. Sutoko, Y. Pang, Y. Horimoto, M. Anzai, T. Niino, Y. Sakai
- Organizer
  International Conference on Biofabrication 2014
- Place of Presentation
  Pohang, Korea
- Year and Date
  2014-09-28 – 2014-10-01
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] Engineering of Implantable Liver Tissue Equivalent based on Three-dimensional Scaffold fabrication and Cellular Aggregate Assembly
- Author(s)
  Yuan PANG, Yohei HORIMOTO, Toshiki NIINO, Yasuyuki SAKAI
- Organizer
  The 4th International Conference on Additive Manufacturing and Bio-Manufacturing
- Place of Presentation
  北京
- Year and Date
  2014-11-12 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] SPG膜乳化法によるヘモグロビンベース新規人工酸素運搬体の開発
- Author(s)
  Lai Yao-Tong、佐藤真優・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  第11回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜、神奈川
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] 細胞・組織培養における生理学的酸素供給
- Author(s)
  酒井康行
- Organizer
  第12回　がんとハイポキシア研究会
- Place of Presentation
  佐賀
- Year and Date
  2014-11-21 – 2014-11-22
- Invited
- Data Source
  KAKENHI-PROJECT-13F03713
[Presentation] Preparation of uniformly-sized microspheres of hemoglobin and albumin as oxygen carriers by the Shirasu porous glass membrane emulsification technique
- Author(s)
  Yao-Tong Lai, Mayu Sato, Yukimitsu Suzuki, Kazuki Akamatsu, Shin-ichi Nakao, Sakai Yasuyuki, Taichi Ito
- Organizer
  Symposium on New Technology for Cell-based Drug Assay
- Place of Presentation
  Ichijo Hall, Yayoi Auditorium, The University of Tokyo、Tokyo
- Data Source
  KAKENHI-PROJECT-23656485
[Presentation] Size control of hemoglobin and albumin-based oxygen carriers by SPG membrane emulsification
- Author(s)
  Lai Yao-Tong・太田誠一・赤松憲樹・中尾真一・酒井康行・伊藤大知
- Organizer
  化学工学会第46回秋期大会
- Place of Presentation
  九州大学
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-22246101
[Presentation] Establishment of a multicellular 3D liver model by co-culturing rat hepatocytes with TMNK-1 based on gas-permeable membranes for drug screening
- Author(s)
  Xiao, W., Perry, G., Komori, K. and Sakai, Y.
- Organizer
  27th Meeting of the Japanese Society for Alternatives to Animal Experiments
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2014-12-05 – 2014-12-07
- Data Source
  KAKENHI-PROJECT-13F03713

1. SUZUKI Motoyuki (10011040)

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63. YUAN Pang

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64. YAO-TONG Lai

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65. STEPHANIE Liana Utami Sutoko

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77. TIXER Agnes

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Sakai Yasuyuki 酒井 康行

SAKAI Yasuyuki 酒井 康行

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Limitations of ultra-high density and low cost in amplification and differentiation of human iPS cellsPrincipal Investigator

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Elucidation of the physiological role of heterogeneous hepatocytes and its application to drug discovery and medicinePrincipal Investigator

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Crosstalks between different organs cultured in OrganS on-a-chipPrincipal Investigator

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血管・尿排泄経路を有する次世代腎臓オルガノイドの作成Principal Investigator

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Universal implantation platform of regenerated endocrine tissues with rapid hormone secretion through blood flowPrincipal Investigator

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Development of a microfluidic biochip for hepatic induced pluripotent stem cell differentiationPrincipal Investigator

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Sakai Yasuyuki 酒井康行

SAKAI Yasuyuki 酒井康行