ONO Masaya 尾野雅哉

… Alternative Names

尾野雅哉オノマサヤ

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Researcher Number	00270900
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2021: 国立研究開発法人国立がん研究センター, 研究所, 研究員 2016 – 2018: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2014: 国立がんセンター研究所, 化学療法部, 室長 2012: 国立がんセンター研究所, 化学療法部, 室長 2010: 国立がんセンター, 化学療法部, 室長 … More 2007: 国立がんセンター研究所及び東病院臨床開発センター, 化学療法部, 室長 2006: 国立がんセンター(研究所及び東病院臨床開発センター), 化学療法部, 室長 1996: The University of Tokyo, the 1st dept.of surgery, Instructor, 医学部・附属病院, 助手 1996: 東京大学, 医学部附属病院, 助手 1995: 東京大学, 医学部(病), 助手 1995: 東京大学, 医学部・附属病院, 医員 Less
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Pathological medical chemistry / Pain science / Tumor biology and related fields / Tumor biology / Biological Sciences / Functional biochemistry / Biological Sciences / Digestive surgery
Keywords	Principal Investigator metastasis / cancer / sLe (x) / focal dedifferentiation / MMP-1 / MMPs / リスクファクター / 肝転移 / sLeX / FD … More / sLe(X) / 血行性転移 / 大腸癌 / MMP … More Except Principal Investigator tumor suppressor / breast cancer / 癌 / 乳癌 / 糖転移酵素 / 神経障害性疼痛 / 薬理学 / 疼痛 / がん性疼痛治療薬 / 新規鎮痛薬 / がん細胞 / 代謝酵素 / 下降性疼痛抑制系 / 鎮痛作用 / μオピオイド受容体 / 難治性疼痛 / がん性疼痛 / 内因性鎮痛ペプチド / がん細胞培養上清 / オピオイド受容体 / 新規内因性鎮痛物質 / 創薬 / HER2 / がん特異的発現亢進因子 / がん抑制因子 / ミトコンドリア / 乳がん / タンパク相互作用阻害 / multistep carcinogenesis / drug discovery / プロテオーム / タンパク質 / 生体機能利用 / ゲノム / mitochondrial regulation / oncogenic signaling / dephosphorylation / phosphorylation / estrogen signaling / 感染症 / client protein / HTLV1 / sythethic lethality / PP2A / アルギニンメチル化 / HSP90 / PRMT5 / NDRG2 / HTLV-1 / ATL / 応答 / 選別 / 小胞輸送 / ゴルジ体 / 超解像顕微鏡 / 小胞体ストレス / タンパク質分解 / 輸送 / 小胞体 / オルガネラ・ゾーン / オルガネラ / PAPS輸送体 / 発生・分化 / 蛋白質 / 糖鎖 / 生理機能 / ノックダウン / RNAi / ES細胞 / ノックアウトマウス / PAPs輸送体 / 硫酸化 / 糖鎖生物学 / プロテオミクス / 質量分析 / T-cell factor-4 / pre-mRNA splicing / splicing factor-1 / actinin-4 / 大腸がん / splicing factor1(SF1) / β-catenin / Wnt シグナル / 大腸癌 / T-cell factor 4(TCF4) / 縮小率 / p53染色 / 放射線照射 / 直腸癌 Less

Analysis of sorting zones involved in protein quality control in the endoplasmic reticulum
- Principal Investigator
  
  Mori Kazutoshi
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Dysregulation of stress signaling leading to oncogenesis by NDRG2-deficicency
- Principal Investigator
  
  Morishita Kazuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  University of Miyazaki
Drug discovery in breast cancer utilizing reactivation of tumor suppressors
- Principal Investigator
  
  KATAGIRI Toyomasa
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  The University of Tokushima
Clarification of novel pathophysiological roles of BIG3 in breast cancer cells
- Principal Investigator
  
  KATAGIRI Toyomasa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Novel pain treatment strategy-Identification of novel analgesic peptide produced by cancer cells and elucidation of analgesic mechanism
- Principal Investigator
  
  MORITA KATSUYA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pain science
- Research Institution
  Hiroshima Bunka Gakuen University
Identification and characterization of a novel unknown glycosyltransferase GTUF in breast cancer cells
- Principal Investigator
  
  MATSUO Taisuke
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Iwate Medical University
  The University of Tokushima
Functional roles of a novel glycosyltrasnferase BCGT1 in breast cancer cells
- Principal Investigator
  
  MATSUO Taisuke
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
Analysis of physiological function of su l fat i on by regulating the expression of PAPS transporter
- Principal Investigator
  
  NISHIHARA Shoko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Soka University
アクチニン4とβカテニンの作用による大腸がんの浸潤転移の分子機構解明
- Principal Investigator
  
  山田哲司
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
直腸癌術前放射線照射における腫瘍内サイトカインの分子生物学的解析とその臨床応用-機能温存直腸癌手術の適応と治療
- Principal Investigator
  
  洲之内広紀
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo
New Risk Factors for Liver Metastasis of Colorectal CancerPrincipal Investigator
- Principal Investigator
  
  ONO Masaya, 澤田俊夫
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2013 2012 2008 2007 2006 Other

All Journal Article Presentation Patent

[Journal Article] Unconventional Secretion of PKCδ Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer2020
- Author(s)
  Yamada Kohji、Oikawa Tsunekazu、Kizawa Ryusuke、Motohashi Saya、Yoshida Saishu、Kumamoto Tomotaka、Saeki Chisato、Nakagawa Chika、Shimoyama Yuya、Aoki Katsuhiko、Tachibana Toshiaki、Saruta Masayuki、Ono Masaya、Yoshida Kiyotsugu
- Journal Title
  
  Cancer Research
  
  Volume: 81 Issue: 2 Pages: 414-425
- DOI
  10.1158/0008-5472.can-20-2009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07621, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-20H03519, KAKENHI-PROJECT-18K15253, KAKENHI-PROJECT-19K16781, KAKENHI-PROJECT-19K08429
[Journal Article] The GALNT6-LGALS3BP axis promotes breast cancer cell growth2020
- Author(s)
  Kimura Ryuichiro、Yoshimaru Tetsuro、Matsushita Yosuke、Matsuo Taisuke、Ono Masaya、Park Jae Hyun、Sasa Mitsunori、Miyoshi Yasuo、Nakamura Yusuke、Katagiri Toyomasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 56 Pages: 581-595
- DOI
  10.3892/ijo.2019.4941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07199, KAKENHI-PLANNED-17H06419
[Journal Article] ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.2020
- Author(s)
  Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H.
- Journal Title
  
  Life science alliance
  
  Volume: 3 Issue: 3 Pages: 201900576-201900576
- DOI
  10.26508/lsa.201900576
- NAID
  120006980545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-18K06222, KAKENHI-PROJECT-19K08843, KAKENHI-PLANNED-15H05931, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04699, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-18H02973, KAKENHI-PROJECT-19H02853, KAKENHI-PROJECT-17K09862, KAKENHI-PROJECT-18K06916, KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-20K07353, KAKENHI-PROJECT-18H03995, KAKENHI-PUBLICLY-20H05314, KAKENHI-ORGANIZER-17H06413
[Journal Article] Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells.2020
- Author(s)
  Ichikawa T, Shanab O, Nakahata S, Shimosaki S, Manachai N, Ono M, Iha H, Shimoda K, Morishita K
- Journal Title
  
  Biochim Biophys Acta Mol Cell Res
  
  Volume: 1867 Issue: 2 Pages: 118615-118615
- DOI
  10.1016/j.bbamcr.2019.118615
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581, KAKENHI-PROJECT-17H04600, KAKENHI-PROJECT-17K09931, KAKENHI-PROJECT-18K07238
[Journal Article] NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.2019
- Author(s)
  Ohata, H., D. Shiokawa, Y. Obata, A. Sato, H. Sakai, M. Fukami, W. Hara, H. Taniguchi, M. Ono, H. Nakagama and K. Okamoto
- Journal Title
  
  Cell Rep
  
  Volume: 28 Pages: 1282-1295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06419
[Journal Article] Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2(low) ATL and various cancer cells.2019
- Author(s)
  Ichikawa, T., O. Shanab, S. Nakahata, S. Shimosaki, N. Manachai, M. Ono, H. Iha, K. Shimoda and K. Morishita
- Journal Title
  
  Biochim Biophys Acta Mol Cell Res
  
  Volume: 1867 Pages: 118615-118615
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06419
[Journal Article] Species-Specific Quantitative Proteomics Profiles of Sarcoma Patient-Derived Models Closely Reflect Their Primary Tumors.2019
- Author(s)
  Shiozawa K, Oyama R, Takahashi M, Kito F, Hattori E, Yoshida A, Kawai A, Ono M, Kondo T.
- Journal Title
  
  Proteomics Clin Appl
  
  Volume: Nov;13(6) Issue: 6 Pages: 1900054-1900054
- DOI
  10.1002/prca.201900054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07791, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18H02933
[Journal Article] Upregulation of IGF2R evades lysosomal dysfunction-induced apoptosis of cervical cancer cells via transport of cathepsins2019
- Author(s)
  Takeda Takashi, Komatsu Masayuki, Chiwaki Fumiko, Komatsuzaki Rie, Nakamura Kanako, Tsuji Kosuke, Kobayashi Yusuke, Tominaga Eiichiro, Ono Masaya, Banno Kouji, Aoki Daisuke, Sasaki Hiroki.
- Journal Title
  
  Cell Death & Disease
  
  Volume: 10(876) Issue: 12 Pages: 1-17
- DOI
  10.1038/s41419-019-2117-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09298, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-18K16812, KAKENHI-PROJECT-19K22892, KAKENHI-PROJECT-18H03330
[Journal Article] A DDX31/mutant-p53/EGFR axis promotes multistep progression of muscle invasive bladder cancer2018
- Author(s)
  Daizumoto Kei、Yoshimaru Tetsuro、Matsushita Yosuke、Fukawa Tomoya、Uehara Hisaori、Ono Masaya、Komatsu Masato、Kanayama Hiro-omi、Katagiri Toyomasa
- Journal Title
  
  Cancer Research
  
  Volume: － Issue: 9 Pages: 2528-2528
- DOI
  10.1158/0008-5472.can-17-2528
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01575, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-16H05153, KAKENHI-PROJECT-17K10551, KAKENHI-PROJECT-18K09136, KAKENHI-PROJECT-17K19601
[Journal Article] Nuclear receptor/Wnt beta-catenin interactions are regulated via differential CBP/p300 coactivator usage.2018
- Author(s)
  Ono M, Lai KKY, Wu K, Nguyen C, Lin DP, Murali R, Kahn M.
- Journal Title
  
  PLoS ONE
  
  Volume: 13 Issue: 7 Pages: e0200714-e0200714
- DOI
  10.1371/journal.pone.0200714
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06419
[Journal Article] A-kinase anchoring protein BIG3 coordinates oestrogen signaling in breast cancer cells2017
- Author(s)
  〇Yoshimaru T, Ono M, Bando Y, Chen YA, Mizuguchi K, Shima H, Komatsu M, Imoto I, Izumi K, Honda J, Miyoshi Y, Sasa M, Katagiri T*
- Journal Title
  
  Nature Communications
  
  Volume: 印刷中
- NAID
  120006535065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05153
[Journal Article] A-kinase anchoring protein BIG3 coordinates oestrogen signalling in breast cancer cells.2017
- Author(s)
  Yoshimaru T, Ono M, Bando Y, Chen YA, Mizuguchi K, Shima H, Komatsu M, Imoto I, Izumi K, Honda J, Miyoshi Y, Sasa M, Katagiri T
- Journal Title
  
  Nature Communications
  
  Volume: 印刷中 Issue: 1 Pages: 15427-15427
- DOI
  10.1038/ncomms15427
- NAID
  120006535065
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461948, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-16H01575, KAKENHI-PROJECT-16H05153
[Journal Article] DDX31 regulates the p53-HDM2 pathway and rRNA gene transcription through its interaction with NPM1in renal cell carcinomas2012
- Author(s)
  Fukawa T, Ono M*, Matsuo T*, Uehara H, Miki T, Nakamura Y, Kanayama H, Katagiri T (*:equal contribution)
- Journal Title
  
  Cancer res
  
  Volume: 72 Pages: 5867-5877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790369
[Journal Article] Sequential glycosyltransfer reactions on a microfluidic device : Synthesis of a glycosaminoglycan linkage region tetrasaccharide.2008
- Author(s)
  Ono, Y.
- Journal Title
  
  Lab. on a Chip 8
  
  Pages: 2168-2173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370051
[Journal Article] Increased susceptibility of Sfl(+/-)mice to azoxymethane-induced colon tumorigenesis2007
- Author(s)
  Shitashige M, Satow R, Honda K, Ono M, Hirohashi S, Yamada T
- Journal Title
  
  Cancer Sci Dec;98(12)
  
  Pages: 1862-1867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013052
[Journal Article] Functional Interaction of DNA Topoisomerase IIα with the S-Catenin and T-Cell Factor-4 Complex2007
- Author(s)
  Huang L, Shitashige M, Satow R, Honda K, Ono M, YunJ I, Tomida A, Tsuruo T, Hirohashi S, Yamada T
- Journal Title
  
  Gastroenterology Nov;133(5)
  
  Pages: 1569-1578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013052
[Journal Article] Label-free quantitative proteomics using large peptide data sets generated by nanoflow liquid chromatography and mass spectrometry2006
- Author(s)
  尾野雅哉, 他
- Journal Title
  
  Molecular and Cellular Proteomics 5(7)
  
  Pages: 1338-1347
- Data Source
  KAKENHI-PROJECT-18013052
[Journal Article] Expression and Gene Amplification of Actinin-4 in Invasive Ductal Carcinoma of the Pancreas
- Author(s)
  Kikuchi S, Honda K, Tsuda H, Hiraoka N, Imoto I, Kosuge T, Umaki T, Onozato K, Shitashige K, Yamaguchi U, Ono M, Tsuchida A, Aoki T, Inazawa J, Hirohashi S, Yamada T
- Journal Title
  
  Clin Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013052
[Journal Article] Distinct Gene-expression-defined Classes of Gastrointestinal Stromal Tumor
- Author(s)
  Yamaguchi U, Nakayama R, Honda K, Ichikawa H, Hasegawa T, Shitashige M, Ono M, Shoji A, Sakuma T, Ruwabara H, Shimada Y, Sasako M, Shimoda T, Kawai A, Hirohashi S, Yamada T
- Journal Title
  
  J CIin Oncol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013052
[Journal Article] Regulation of Wnt Signaling by the Nuclear Pore Complex.
- Author(s)
  ShitashigeM, Satow R, Honda K, Ono M, Hirohashi S, Y amada T.
- Journal Title
  
  Gastroenterology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013052
[Patent] 膵癌の新規腫瘍マーカー2007
- Inventor(s)
  尾野雅哉、山田哲司、廣橋説雄
- Industrial Property Rights Holder
  財団法人ヒューマンサイエンス振興
- Filing Date
  2007-07-25
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] ミトコンドリアBIG3-PHB2複合体の脆弱性を標的にしたトリプルネガティブ乳癌治療法の可能性考察2021
- Author(s)
  相原仁, 吉丸哲郎, 尾野雅哉, 笹三徳, 三好康雄, 片桐豊雅
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] トリプルネガティブ乳癌細胞のミトコンドリア構造・機能制御におけるBIG3-PHB2複合体の病態生理的役割と創薬開発2020
- Author(s)
  相原仁, 吉丸哲郎, 尾野雅哉, 笹三徳 , 三好康雄, 片桐豊雅
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] BIG3-PHB2複合体の形成が，HER2陽性乳癌のトラスツズマブ耐性獲得を誘導する2020
- Author(s)
  吉丸哲郎, 松下洋輔, 尾野雅哉, 笹三徳, 三好康雄, 片桐豊雅
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] ミトコンドリアBIG3-PHB2複合体阻害は骨肉腫の悪性化を抑制する2020
- Author(s)
  土岐俊一, 吉丸哲郎, 相原仁, 松下洋輔, 尾野雅哉, 片桐豊雅
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] がん抑制遺伝子NDRG2発現低下によるJak/STAT情報伝達系活性化機構2019
- Author(s)
  市川朝永、中畑新吾、尾野雅哉、中武彩子、阪本訓代、森下和広
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] PRMT5 inhibition is synthetic lethal with loss of NDRG2 through the suppression of HSP90A in ATL2019
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Masaya Ono, Hidekatsu Iha, and Kazuhiro Morishita.
- Organizer
  第81回日本血液学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Anti-transferrin receptor1(TFR1)antibody is a promising drug candidate for the treatment of adult T-cell leukemia/lymphoma2019
- Author(s)
  Shingo Nakahata, Shunsuke Shimosaki, Tomonaga Ichikawa, Takuro Kameda, Tomonori Hidaka, Yoko Kubuki, Gene Kurosawa, Kazuya Shimoda, Kazuhiro Morishita
- Organizer
  19th INTERNATIONAL CONFERENCE ON HUMAN RETROVIROLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] DDX31 cooperates with mutant p53 and EGFR to promote the multistep progression of invasive bladder cancer2018
- Author(s)
  Toyomasa Katagiri, Kei Daizumoto, Tetsuro Yoshimaru, Yosuke Matsushita, Tomoya Fukawa, Ono Masaya and Hiro-omi Kanayama
- Organizer
  American Association For Cancer Research ANNUAL MEETING 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19601
[Presentation] High efficacy of anti-TFR1 antibody against the growth of mogamulizmab-resistant ATLL cells2018
- Author(s)
  Shingo Nakahata, Shunsuke Shimosaki, Tomonaga Ichikawa, Takuro Kameda, Tomonori Hidaka, Yoko Kubuki, Gene Kurosawa, Kazuya Shimoda, Kazuhiro Morishita.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] DDX31 cooperates with mutant p53 and EGFR to promote the multistep progression of invasive bladder cancer2018
- Author(s)
  Toyomasa Katagiri, Kei Daizumoto, Tetsuro Yoshimaru, Yosuke Matsushita, Tomoya Fukawa, Ono Masaya and Hiro-omi Kanayama
- Organizer
  American Association For Cancer Research ANNUAL MEETING 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05153
[Presentation] Maintenance of HSP90A by PRMT5 arginine methylation by NDRG2-deficient ATLL and other cancers2018
- Author(s)
  Kazuhiro Morishita1 , Tomonaga Ichikawa1 , Shingo Nakahata1 , Masaya Ono
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] アルギニンメチル化転移酵素PRMT5異常活性によるATL発症機構の解析.2018
- Author(s)
  市川朝永、Obeid Shanab、中畑新吾、尾野雅哉、伊波英克、中武彩子、阪本訓代、森下和広
- Organizer
  第5回日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Short-form of BCL11B contributes to tumorigenesis of adult T-cell leukemia/lymphoma.2018
- Author(s)
  Happy Kurnia Permatasari, Shingo Nakahata, Tomonaga Ichikawa, Kotaro Shide, Takuro Kameda, Kazuya Shimoda, Masaya Ono, Kazuhiro Morishita.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] トリプリネガティブ乳がんにおけるRHBDL2の役割解明と抗体創薬の可能性2018
- Author(s)
  奥村和正, 松下洋輔, 小松正人, 木村竜一朗, 吉丸哲郎, 尾野雅哉, 三好康雄, 本田純子, 笹三徳, 丹黒章, 片桐豊雅
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06419
[Presentation] Arginine methylation of HSP90A by protein arginine methyltransferase PRMT5 promotes development of adult T-cell leukemia.2018
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Masaya Ono, Hidekatsu Iha, and Kazuhiro Morishita.
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] アルギニンメチル化によるHSP90A活性調節機構の解析2017
- Author(s)
  市川朝永,　Obeid Shanab,　中畑新吾,　伊波英克,　尾野雅哉,　中武彩子,　阪本訓代,　森下和広
- Organizer
  平成29年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] Synthetic lethality of PRMT5 inhibition in NDRG2-deficient adult T-cell leukemia through HSP90A dysfunction2017
- Author(s)
  Tomonaga Ichikawa, Obeid Shanab, Shingo Nakahata, Shunsuke Shimosaki, Nawin Manachai, Hidekatsu Iha, Kazuya Shimoda, Masaya Ono, Mohammed N. Ismail, Ahmed Y. Nassar and Kazuhiro Morishita. 
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] 成人T細胞白血病(ATL)に対するアルギニンメチル化転移酵素PRMT5阻害による抗腫瘍効果の検討2017
- Author(s)
  市川朝永、Obeid Shanab、中畑新吾、伊波英克、尾野雅哉、中武彩子、阪本訓代、森下和広
- Organizer
  第4回日本HTLV-1学会
- Data Source
  KAKENHI-PROJECT-17H03581
[Presentation] BIG3-PHB2相互作用を標的とした前立腺がん治療法の開発の可能性2016
- Author(s)
  瀧亮祐, 吉丸哲郎, 大豆本圭, 松下洋輔, 木村竜一朗, 尾野雅哉, 片桐豊雅
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H05153
[Presentation] A novel A-kinase anchoring protein BIG3, coordinates estrogen signalling in breast cancer cells2016
- Author(s)
  Tetsuro Yoshimaru, Ono Masaya, Mizuguchi Kenji, Miyoshi Yasuo, Mitsunori Sasa and Toyomasa Katagiri
- Organizer
  The 12th International Conference on Protein Phosphatase
- Place of Presentation
  近畿大学　大阪府東大阪市
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05153
[Presentation] がん特異的糖転移酵素BCGT1 による小胞体ストレス制御を介した新規乳癌細胞増殖機構の解明2013
- Author(s)
  松尾泰佑、尾野雅哉、吉丸哲郎、小松正人、三好康雄、笹三徳、片桐豊雅
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25860240
[Presentation] Actinin-4-mediated inhibition of cell proliferation and mass spectrometry analysis of the native proteincomplex containing actinin-4 inprostate cancer cells2007
- Author(s)
  Tomohiko Hara, Kazufumi Honda, Miki Shitashige, Masaya Ono, Hideyasu Matsuyama, Katsusuke Naito, Setsuo Hirohashi, Tesshi Yamada
- Organizer
  The 98th annual meeting, American Association for Cancer Research
- Place of Presentation
  米国(ロサンゼルス)
- Year and Date
  2007-04-14
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] Large-scale identification of proteins whose expression is regulated by the β-catenin and T-cell factor-4(TCF4) complex in colorectal cancer cells2007
- Author(s)
  Miki Shitashige, Kazufumi Honda, Masaya Ono, Setsuo Hirohashi, and Tesshi Yamada
- Organizer
  The 6th Annual World Congress, HumanProtedme Organization
- Place of Presentation
  韓国(ソウル)
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] Biomarker Discovery by 2-Dimensional Image Converted Analysis of Liquid Chromatography and Mass Spectrometry (2DICAL)2007
- Author(s)
  Ayako Negishi, Masaya Ono, Junichi Matsubara, Emiko Chikui, Kazufumi Honda, Miki Shitashige, Ken Omura, Setsuo Hirohashi, and Tesshi Yamada
- Organizer
  The 6th Annual World Congress, Human Proteome Organization
- Place of Presentation
  韓国(ソウル)
- Year and Date
  2007-10-08
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] I dentification of biomarkers and therapy targets by oncogenomics and oncoproteomcs2007
- Author(s)
  Tesshi Yamada, Kazufumi Honda, Miki Shitashige, Masaya Ono, Setsuo Hirohashi
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  神奈川県(横浜市)
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] Biomarker Discovery by 2-dimensional image converted analysis of liquid chromatography and mass spectrometry (2DICAL)2007
- Author(s)
  Ayako Negishi, Masaya Ono, Junichi Matsuhara, Emiko Chikui, Ken Omura, Setsuo Hirohashi, Tesshi Yamada
- Organizer
  第66回日本癌学会学衛総会
- Place of Presentation
  神奈川県(横浜市)
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] プロテオーム解析によるバイオマーカー探索と臨床応用.2007
- Author(s)
  山田哲司、本田一文、下重美紀、尾野雅哉
- Organizer
  第58回目本電気泳動学会総会
- Place of Presentation
  山口県(宇部市)
- Year and Date
  2007-11-08
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] Mass spectrometry analysis of the native protein complexcontaining actinin-4 in prostate cancer cells.-Arole of actinin-4protein complex in the intracellular traffickingof cell surface proteins-2007
- Author(s)
  Kazufumi Honda, Miki Shitashige, Masaya Ono, Setsuo Hirohashi, Tesshi Yamada
- Organizer
  The 6th Annual World Congress, Human ProteomeOrganization
- Place of Presentation
  韓国(ソウル)
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] Proteomic analysis of β-catenin-mediated colorectal,carcinogeneses2007
- Author(s)
  Tesshi Yamada, Miki Shitashige, Kazufki Honda, Masaya Ono, Setsuo Hirohashi
- Organizer
  The 6th Annual World Congress, Human Proteme Organizaeion
- Place of Presentation
  韓国(ソウル)
- Year and Date
  2007-10-10
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] Peptide alignment of nano-flow liquid chromatography and mass spectrometry(LC-MS) enables large-scale comparisons of the human plasmal proteome2007
- Author(s)
  Masaya Ono, Ayako Negishi, Miki Shitashige, Kazufumi Honda, Setsuo Hirohashi, Tesshi Yamada
- Organizer
  The 6th Annual World Congress, Human Proteome Organization
- Place of Presentation
  韓国(ソウル)
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-18013052
[Presentation] 悪性度の高いトリプルネガティブ乳癌における核内19S-proteasome関連遺伝子(nPAG1)の役割
- Author(s)
  小松正人、吉丸哲郎、尾野雅哉、松尾泰佑、清谷一馬、三好康雄、笹三徳、片桐豊雅
- Organizer
  第73回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860240

1. KATAGIRI Toyomasa (60291895)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
2. MATSUO Taisuke (70533222)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. MIYOSHI Yasuo (50283784)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. BANDO Yoshimi (00238239)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YOSHIMARU Tetsuro (80424729)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. MATSUSHITA Yosuke (70634450)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. MUZUGUCHI Kenji (50450896)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. OTAKA Akira (20201973)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 洲之内広紀 (80221331)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 石丸悟正 (70272557)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SASA Mitsunori

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. NISHIHARA Shoko (00164575)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUDO Takashi (20288062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TOYODA Hidenao (70217579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Mori Kazutoshi (70182194)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. Morishita Kazuhiro (80260321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MORITA KATSUYA (10116684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山田哲司 (30221659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
19. 本田一文 (10260936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
20. 下重美紀 (00392340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
21. 澤田俊夫 (50143441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 西頭英起 (00332627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 名黒功 (80401222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 蜷川暁 (80647991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 中畑新吾 (80437938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
26. 市川朝永 (80586230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
27. 本山直世 (70509661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 北山友也 (60363082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 土肥敏博 (00034182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. YOKOYAMA Tadashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. SASAKI Shin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 樋口芳樹

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 篠崎大

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 鮫島伸一

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 渡辺聡明

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. TORII Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 立花利公

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 山田幸司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 吉田彩舟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 森下和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 12 results
41. 近藤格

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 川井章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
43. 冨永英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ONO Masaya 尾野 雅哉

尾野 雅哉 オノ マサヤ

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New Risk Factors for Liver Metastasis of Colorectal CancerPrincipal Investigator

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[Journal Article] Unconventional Secretion of PKCδ Exerts Tumorigenic Function via Stimulation of ERK1/2 Signaling in Liver Cancer2020

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[Journal Article] The GALNT6-LGALS3BP axis promotes breast cancer cell growth2020

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[Journal Article] ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.2020

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[Journal Article] Novel PRMT5-mediated arginine methylations of HSP90A are essential for maintenance of HSP90A function in NDRG2low ATL and various cancer cells.2020

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ONO Masaya 尾野雅哉

尾野雅哉オノマサヤ