Sekine Keisuke 関根圭輔

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SEKINE Keisuke 関根圭輔

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Researcher Number	00323569
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
Affiliation (based on the past Project Information) *help	2020 – 2024: 国立研究開発法人国立がん研究センター, 研究所, ユニット長 2019: 東京大学, 医科学研究所, 准教授 2018: 横浜市立大学, 医学部, 講師 2009 – 2017: Yokohama City University, 医学部, 助教 2009: 東京大学, 分子細胞生物学研究所, 助手 … More 2007 – 2008: Meikai University, 歯学部, 助教 2006 – 2008: 明海大学, 歯学部, 助手 2001 – 2005: 東京大学, 分子細胞生物学研究所, 助手 Less
Review Section/Research Field	Principal Investigator General surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related / Functional basic dentistry / Cell biology Except Principal Investigator Basic Section 49020:Human pathology-related / Functional basic dentistry / Morphological basic dentistry / Biological Sciences / Basic Section 50010:Tumor biology-related / Pathobiological dentistry/Dental radiology / Immunology / General surgery
Keywords	Principal Investigator オルガノイド / 膵癌 / 癌 / シングルセルゲノミクス / 転移 / 癌幹細胞 / 細胞・組織 / iPS細胞 / RNAシークエンス / 再生医療 … More / がん / ゲノム編集 / 癌オルガノイド / 肝臓 / シングルセルRNAシークエンス / シングルセル解析 / 移植・再生医療 / シングルセル / 癌微小環境 / Organoid / iPSC / 肝疾患 / 幹細胞 / 再生医学 / リプログラミング / エピジェネティクス / 膵臓 / がん幹細胞 / 膵癌幹細胞 / サイクリン / Rb / 細胞周期 / インターフェロン / 口腔扁平上皮癌 / 口腔生化学 / Cell cvcle / Cell cycle / 細胞増殖 / 口腔癌細胞 / インターフェロンγ / シグナル伝達 / サイトカイン / 造血因子 … More Except Principal Investigator シグナル伝達 / マクロファージ / 発生 / サイトカイン / 上皮細胞 / 血管 / 免疫 / 細胞分化 / 幹細胞 / 正常気管支上皮 / 前がん病変 / 正常組織 / 肺がん / 胆管がん / 膵がん / 免疫環境 / がん微小環境 / 発生・分化 / 免疫学 / 細菌 / 歯学 / HT1080 / CD13 / ＨＴ１０８０ / がん細胞 / NGR配列 / Fibronectin / ＣＤ１３ / 破骨細胞 / Signal / Regeneration / Cell surface antigen / Liver injury / Stem cell / Differentiation / Liver / Development / Notch / 文化 / シグナル / 再生 / 細胞膜抗原 / 肝障害 / 肝臓 / antigen / cytokine / T cell / epithelial cells / apoptosis / denritic cells / macrophage / thymus / リンパ球 / 抗原提示 / T細胞 / アポトーシス / 樹状細胞 / 胸腺 / 膵前駆細胞 / 分化誘導 / 膵島 / 糖尿病 / 内胚葉前駆細胞 / iPS細胞 / 三次元培養 / 膵島移植 / 膵臓 / siRNA / β-カテニン / sclerostin / sFrp2 / 破骨細胞上駆細胞株4B12細胞 / 破細胞分化 / Sclerostin / Tm7sf4 / canonical経路 / Wnt / DC-STAMP / TCF/LEF / GSK-3β阻害 / β-catenin / 内因性Wntシグナル / 破骨細胞前駆細胞株4B12細胞 / 破骨細胞分化 / 炎症 / 感染 / 骨代謝学 / 分化制御 / 組織形成 / 低酸素 / IL-13 / 抗炎症 / 遺伝子発現 / 口腔扁平上皮癌 / CD163 / 免疫組織 / IL-4 / STAT6 / Il-4 / 腫瘍 / M2マクロファージ / CXCL1 / ケモカイン / STAT1 / インターフェロン / リポ多糖 / 炎症性遺伝子 / 遺伝子制御 / 炎症学 / 生理活性 / 発現制御 / 感染症 / JAK / STAT / MTM / 細胞膜透過性 / IRAK-M / SOCS / 蛋白質療法 / TLR / 口腔細菌学 / 分化 / 癌細胞 / モノクローナル抗体 / 肝細胞 Less

Vascular roles in tumor immune microenvironment of pancreatic and biliary cancers
- Principal Investigator
  
  平岡伸介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
Spatiotemporal interactions in metastatic nichesPrincipal Investigator
- Principal Investigator
  
  関根圭輔
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  National Cancer Center Japan
膵癌の肝転移により生じる転移ニッチの1細胞遺伝子発現解析
- Principal Investigator
  
  海野研二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  National Cancer Center Japan
Study of the mechanisms of lung cancer development through multi-omics analysis of normal tissues and precancerous lesions of the lung
- Principal Investigator
  
  吉田健一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  National Cancer Center Japan
Development of organoid gene analysis system elucidating individual differences in cancer.Principal Investigator
- Principal Investigator
  
  SEKINE KEISUKE
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  National Cancer Center Japan
Elucidation of the metastasis mechanism by constructing a metastasis modelPrincipal Investigator
- Principal Investigator
  
  関根圭輔
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  National Cancer Center Japan
Elucidation and control of pancreatic cancer-stroma interaction by artificial cancer tissue constructionPrincipal Investigator
- Principal Investigator
  
  Sekine Keisuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  National Cancer Center Japan
  The University of Tokyo
Semi-exhaustive functional screening of cell-cell interaction factors in human iPSC mini-liverPrincipal Investigator
- Principal Investigator
  
  Sekine Keisuke
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  The University of Tokyo
  Yokohama City University
Cell lineage analysis of changes in characteristics of pancreatic cancer cells at single cell level(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  Sekine Keisuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Clarification of the role of CD13 combined with N-terminal fragment of fibronectin on inflammatory bone resorption.
- Principal Investigator
  
  AMANO Shigeru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Meikai University
Single cell heterogeneity analysis of endothelial and mesenchymal cellsPrincipal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Dissecting pancreatic cancer cell evolution at single cell level.Principal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Visualization of functional hepatic cells derived from human iPS cells.Principal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Generation of pancreatic islet-like tissue by using an innovative 3D-culture method.
- Principal Investigator
  
  TANIGUCHI Hideki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Identification of pancreatic cancer stem cell lineage during pancreatic tumorigenesisPrincipal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Elucidation of liver carcinogenesis mechanism by epigenetic reprogramming.Principal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Yokohama City University
Investigation of the role of endogenous Wnt signaling in osteoclast differentiation and function
- Principal Investigator
  
  AMANO Shigeru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Regulatory mechanisms of gene expression in anti-inflammatory M2 macrophages
- Principal Investigator
  
  OHMORI Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Molecular mechanisms of resistance to interferon-gamma in human oral squamous carcinoma.Principal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Yokohama City University
A fundamental study about development of the protein therapy using suppressors of TLR signaling
- Principal Investigator
  
  HANAZAWA Shigemasa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Nihon University
Mechanism of Transcriptional Repression of Inflammatory Gene Expression by STAT1
- Principal Investigator
  
  OHMORI Yoshihiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Molecular dissection of interferon-resistance in oral squamous cell carcinomaPrincipal Investigator
- Principal Investigator
  
  SEKINE Keisuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Meikai University
Mechanism of liver development
- Principal Investigator
  
  MIYAJIMA Atsushi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Molecular mechanism of proliferation and differentiation of hepatocyte.
- Principal Investigator
  
  MIYAJIMA Atsushi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Functions of Thymic Epithelial Cells
- Principal Investigator
  
  MIYAJIMA Atsushi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
間葉系幹細胞の発生,増殖と分化機構の解析Principal Investigator
- Principal Investigator
  
  関根圭輔
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo

[Book] 「がんゲノムペディア　-77のキーワードで理解するゲノム医療とゲノム研究-」2024
- Author(s)
  関根圭輔（柴田龍弘／編）
- Total Pages
  255
- Publisher
  羊土社
- ISBN
  9784758121309
- Data Source
  KAKENHI-PROJECT-22K19575
[Book] がんゲノムペディア　-77のキーワードで理解するゲノム医療とゲノム研究-2024
- Author(s)
  関根圭輔（柴田龍弘／編）
- Total Pages
  255
- Publisher
  羊土社
- ISBN
  9784758121309
- Data Source
  KAKENHI-PROJECT-23K24400
[Book] 患者由来がんモデルを用いたがん研究実践ガイド、佐々木博己／編2019
- Author(s)
  関根圭輔
- Total Pages
  294
- Publisher
  羊土社
- ISBN
  9784758122429
- Data Source
  KAKENHI-PROJECT-18K19589
[Book] 患者由来がんモデルを用いたがん研究実践ガイド、佐々木博己／編2019
- Author(s)
  関根圭輔
- Total Pages
  294
- Publisher
  羊土社
- ISBN
  9784758122429
- Data Source
  KAKENHI-PROJECT-19H03718
[Book] Organ Regeneration Based on Developmental Biology2017
- Author(s)
  Keisuke Sekine, Takanori Takebe, Hideki Taniguchi
- Total Pages
  257
- Publisher
  Springer book
- ISBN
  9789811037665
- Data Source
  KAKENHI-PROJECT-15H04922
[Book] Organ Regeneration Based on Developmental Biology2017
- Author(s)
  Keisuke Sekine, Takanori Takebe, Hideki Taniguchi
- Total Pages
  257
- Publisher
  Springer book
- ISBN
  9789811037665
- Data Source
  KAKENHI-PROJECT-16K15597
[Book] Organ Regeneration Based on Developmental Biology2017
- Author(s)
  Keisuke Sekine, Takanori Takebe, Hideki Taniguchi
- Total Pages
  257
- Publisher
  Springer book
- ISBN
  9789811037689
- Data Source
  KAKENHI-PROJECT-15KK0314
[Book] 現代栄養学を理解するための分子生物学入門(加藤茂明/編著)2010
- Author(s)
  関根圭輔
- Publisher
  光生館
- Data Source
  KAKENHI-PROJECT-21791812
[Book] 現代栄養学を理解するための分子生物学入門(加藤茂明/編著)2010
- Author(s)
  関根圭輔
- Publisher
  光生館
- Data Source
  KAKENHI-PROJECT-21791812
[Book] Medical Bio(肝臓が糖代謝能を獲得するしくみ, 5(2))2008
- Author(s)
  関根圭輔, 陳彦榮, 宮島篤
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] Development of a novel co-culture system using human pancreatic cancer cells and human iPSC-derived stellate cells to mimic the characteristics of pancreatic ductal adenocarcinoma in?vitro2023
- Author(s)
  Kometani Tatsuya、Kamo Koki、Kido Taketomo、Hiraoka Nobuyoshi、Chibazakura Taku、Unno Kenji、Sekine Keisuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 658 Pages: 1-9
- DOI
  10.1016/j.bbrc.2023.03.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15434, KAKENHI-PROJECT-21K05510, KAKENHI-PROJECT-22K19575, KAKENHI-ORGANIZER-23H03834, KAKENHI-PLANNED-23H03836, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-23K24400
[Journal Article] Highly Sensitive Detection of Human Pluripotent Stem Cells by Loop-Mediated Isothermal Amplification2022
- Author(s)
  Yasui Ryota、Matsui Atsuka、Sekine Keisuke、Okamoto Satoshi、Taniguchi Hideki
- Journal Title
  
  Stem Cell Reviews and Reports
  
  Volume: 18 Issue: 8 Pages: 2995-3007
- DOI
  10.1007/s12015-022-10402-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19575, KAKENHI-PROJECT-21H04830, KAKENHI-PROJECT-23K24400
[Journal Article] High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development2022
- Author(s)
  Krumm J, Sekine K, Samaras P, Brazovskaja A, Breunig M, Yasui R, Kleger A, Taniguchi H, Wilhelm M, Treutlein B, Camp JG, Kuster B
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 13 Pages: 110604-110604
- DOI
  10.1016/j.celrep.2022.110604
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03718, KAKENHI-PROJECT-22K19575, KAKENHI-PROJECT-23K24400
[Journal Article] Robust parameter design of human induced pluripotent stem cell differentiation protocols defines lineage-specific induction of anterior-posterior gut tube endodermal cells.2021
- Author(s)
  Yasui R, Sekine K, Yamaguchi K, Furukawa Y, Taniguchi H
- Journal Title
  
  Stem Cells
  
  Volume: 39 Issue: 4 Pages: 429-442
- DOI
  10.1002/stem.3326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04830, KAKENHI-PROJECT-19H03718, KAKENHI-PROJECT-20K07563
[Journal Article] Human Organoid and Supporting Technologies for Cancer and Toxicological Research2021
- Author(s)
  Sekine K
- Journal Title
  
  Frontiers in Genetics
  
  Volume: 12 Pages: 759366-759366
- DOI
  10.3389/fgene.2021.759366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03718
[Journal Article] Clever Experimental Designs: Shortcuts for Better iPSC Differentiation.2021
- Author(s)
  Yasui R, Sekine K, Taniguchi H.
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 12 Pages: 3540-3540
- DOI
  10.3390/cells10123540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04830, KAKENHI-PROJECT-19H03718
[Journal Article] Establishment of PDX‐derived salivary adenoid cystic carcinoma cell lines using organoid culture method2020
- Author(s)
  Takada Kentaro、Aizawa Yoshihiro、Sano Daisuke、Okuda Ryo、Sekine Keisuke、Ueno Yasuharu、Yamanaka Shoji、Aoyama Jun、Sato Kaname、Kuwahara Tatsu、Hatano Takashi、Takahashi Hideaki、Arai Yasuhiro、Nishimura Goshi、Taniguchi Hideki、Oridate Nobuhiko
- Journal Title
  
  International Journal of Cancer
  
  Volume: 148 Issue: 1 Pages: 193-202
- DOI
  10.1002/ijc.33315
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09873, KAKENHI-PROJECT-19K09895, KAKENHI-PROJECT-20K08952, KAKENHI-PROJECT-19H03718, KAKENHI-PROJECT-17K10057, KAKENHI-PROJECT-18K09382, KAKENHI-PROJECT-20K18259
[Journal Article] Generation of human induced pluripotent stem cell-derived liver buds with chemically defined and animal origin-free media2020
- Author(s)
  Sekine K, Ogawa S, Tsuzuki S, Kobayashi T, Ikeda K, Nakanishi N, Takeuchi K, Kanai E, Otake Y, Okamoto S, Kobayashi T, Takebe T, Taniguchi H.
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 17937-17937
- DOI
  10.1038/s41598-020-73908-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02800, KAKENHI-PROJECT-19H03718, KAKENHI-PROJECT-19K22416
[Journal Article] Robust detection of undifferentiated iPSC among differentiated cells.2020
- Author(s)
  Sekine K, Tsuzuki S, Yasui R, Kobayashi T, Ikeda K, Hamada Y, Kanai E, Camp JG, Treutlein B, Ueno Y, Okamoto S, Taniguchi H.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 10293-10293
- DOI
  10.1038/s41598-020-66845-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08952, KAKENHI-PROJECT-19H03718
[Journal Article] Human iPSC-Derived Posterior Gut Progenitors Are Expandable and Capable of Forming Gut and Liver Organoids.2018
- Author(s)
  Zhang R-R, Koido M, Tadokoro T, Ouchi R, Matsuno T, Ueno Y, Sekine K, Takebe T*, Taniguch H
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Issue: 3 Pages: 780-793
- DOI
  10.1016/j.stemcr.2018.01.006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-17K10517, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-16K15597, KAKENHI-PROJECT-16K19462, KAKENHI-PROJECT-18K19589, KAKENHI-PROJECT-15KK0314
[Journal Article] Optimal Hypoxia Regulates Human iPSC-Derived Liver Bud Differentiation through Intercellular TGFB Signaling2018
- Author(s)
  Ayabe Hiroaki、Anada Takahisa、Kamoya Takuo、Sato Tomoya、Kimura Masaki、Yoshizawa Emi、Kikuchi Shunyuu、Ueno Yasuharu、Sekine Keisuke、Camp J. Gray、Treutlein Barbara、Ferguson Autumn、Suzuki Osamu、Takebe Takanori、Taniguchi Hideki
- Journal Title
  
  Stem Cell Reports
  
  Volume: 11 Issue: 2 Pages: 306-316
- DOI
  10.1016/j.stemcr.2018.06.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10517, KAKENHI-PROJECT-18K19589, KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-18H02800
[Journal Article] Recapitulation of hepatitis B virus?host interactions in liver organoids from human induced pluripotent stem cells2018
- Author(s)
  Nie Yun-Zhong、Zheng Yun-Wen、Miyakawa Kei、Murata Soichiro、Zhang Ran-Ran、Sekine Keisuke、Ueno Yasuharu、Takebe Takanori、Wakita Takaji、Ryo Akihide、Taniguchi Hideki
- Journal Title
  
  EBioMedicine
  
  Volume: 35 Pages: 114-123
- DOI
  10.1016/j.ebiom.2018.08.014
- NAID
  120007128498
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10517, KAKENHI-PROJECT-18K19589, KAKENHI-PROJECT-18F18101, KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-16K15604, KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-18H02800, KAKENHI-PROJECT-18H02866
[Journal Article] Self-Condensation Culture Enables Vascularization of Tissue Fragments for Efficient Therapeutic2018
- Author(s)
  Yoshinobu Takahashi, Keisuke Sekine, Tatsuya Kin, Takanori Takebe, Hideki Taniguchi
- Journal Title
  
  Cell Reports
  
  Volume: 6 Issue: 6 Pages: 1620-1629
- DOI
  10.1016/j.celrep.2018.03.123
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-15H05677, KAKENHI-PROJECT-15J10041, KAKENHI-PROJECT-16K15597, KAKENHI-PROJECT-17K10517, KAKENHI-PROJECT-18K19589, KAKENHI-PROJECT-18H02800
[Journal Article] Chitosan promotes cancer progression and stem cell properties in association with Wnt signaling in colon and hepatocellular carcinoma cells2017
- Author(s)
  Chang Po-Hsiang、Sekine Keisuke、Chao Hsiao-Mei、Hsu Shan-hui、Chern Edward
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 45751-45751
- DOI
  10.1038/srep45751
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-16K15597
[Journal Article] Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells.2017
- Author(s)
  Takebe T*, Sekine K, Kimura M, Yoshizawa E, Funayama S, Nakanishi N, Hisai T, Kobayashi T, Mori A, Ayano S, Ejiri Y, Amimoto N, Yamazaki Y, Ogawa S, Ishikawa M, Kiyota Y, Ueno Y, Taniguchi H
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 10 Pages: 2661-2670
- DOI
  10.1016/j.celrep.2017.11.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-17K10517, KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-15H05677
[Journal Article] Nutritional modulation of mouse and human liver bud growth through a branched-chain amino acid metabolism.2017
- Author(s)
  Koike H, Zhang RR, Ueno Y, Sekine K, Zheng YW, Takebe T, Taniguchi H.
- Journal Title
  
  Development
  
  Volume: 144(6) Pages: 1018-1024
- DOI
  10.1242/dev.143032
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-15H05677, KAKENHI-PROJECT-15H06534, KAKENHI-PROJECT-26293291, KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-16K15597, KAKENHI-PROJECT-15KK0314
[Journal Article] Multilineage communication regulates human liver bud self-organization from pluripotency.2017
- Author(s)
  Camp JG, Sekine K, Gerber T, Loeffler-Wirth H, Binder H, Gac M, Kanton S, Kageyama J, Damm G, Seehofer D, Belicova L, Bickle M, Barsacchi R, Okuda R, Yoshizawa E, Kimura M, Ayabe H, Taniguchi H, Takebe T*, Treutlein B
- Journal Title
  
  Nature
  
  Volume: 546 Issue: 7659 Pages: 533-534
- DOI
  10.1038/nature22796
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-17K10517, KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-15H05677, KAKENHI-PROJECT-16K15597
[Journal Article] Liver Regeneration Using Cultured Liver Bud2017
- Author(s)
  Sekine K, Takebe T, Taniguchi H.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1597 Pages: 207-216
- DOI
  10.1007/978-1-4939-6949-4_15
- ISBN
  9781493969470, 9781493969494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-26293291, KAKENHI-PROJECT-16KT0073, KAKENHI-PROJECT-15KK0314, KAKENHI-PROJECT-15H04922, KAKENHI-PROJECT-15H05677, KAKENHI-PROJECT-16K15597
[Journal Article] The development of humanized liver with Rag1 knockout rats.2014
- Author(s)
  Tsuchida T, Zheng YW, Zhang RR, Takebe T, Ueno Y, Sekine K, Taniguchi H
- Journal Title
  
  Transplant Proc
  
  Volume: 46 Issue: 4 Pages: 1191-3
- DOI
  10.1016/j.transproceed.2013.12.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25461956, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Polycomb group protein Ezh2 regulates hepatic progenitor cell proliferation and differentiation in murine embryonic liver.2014
- Author(s)
  Koike H, Ouchi R, Ueno Y, Nakata S, Obana Y, Sekine K, Zheng YW, Takebe T, Isono K, Koseki H, Taniguchi H.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 8 Pages: 0-2
- DOI
  10.1371/journal.pone.0104776
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-25460488, KAKENHI-PROJECT-25461956, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.2014
- Author(s)
  Takanori Takebe*, Ran-Ran Zhang, Hiroyuki Koike, Masaki Kimura, Emi Yoshizawa, Masahiro Enomura, Keisuke Sekine, Hideki Taniguchi*(*: Correspondence)
- Journal Title
  
  Nature Protocols
  
  Volume: 9(2) Issue: 2 Pages: 396-409
- DOI
  10.1038/nprot.2014.020
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24106510, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Engineering of human hepatic tissue with functional vascular networks2014
- Author(s)
  Takebe T, Koike N, Sekine K, Fujiwara R, Amiya T, Zheng YW, Taniguchi H
- Journal Title
  
  Organogenesis
  
  Volume: 10(2)(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] Fluorescent labeling and visualization of human induced pluripotent stem cells with the use of transcription activatore like effector nucleases2014
- Author(s)
  Sekine K, Takebe T, Taniguchi H.
- Journal Title
  
  Transplant Proc.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] The CD133+CD44+ Precancerous Subpopulation of Oval Cells is a Therapeutic Target for Hepatocellular Carcinoma2014
- Author(s)
  Zheng YW, Tsuchida T, Shimao T, Li B, Takebe T, Zhang RR, Sakurai Y, Ueno Y, Sekine K, Ishibashi N, Imajima M, Tanaka T, and Taniguchi H
- Journal Title
  
  Stem Cells Dev
  
  Volume: (In press) Issue: 18 Pages: 2237-2249
- DOI
  10.1089/scd.2013.0577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25461956, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Tropism of cancer stem cells to a specific distant organ2014
- Author(s)
  Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H.
- Journal Title
  
  In Vivo
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] The CD133+CD44+ Precancerous Subpopulation of Oval Cells is a Therapeutic Target for Hepatocellular Carcinoma2014
- Author(s)
  Zheng YW, Tsuchida T, Shimao T, Li B, Takebe T, Zhang RR, Sakurai Y, Ueno Y, Sekine K, Ishibashi N, Imajima M, Tanaka T, Taniguchi H.
- Journal Title
  
  Stem Cells Dev.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305
[Journal Article] Tropism of cancer stem cells to a specific distant organ.2014
- Author(s)
  Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H.
- Journal Title
  
  In Vivo.
  
  Volume: 28 Pages: 361-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670585
[Journal Article] The evidence of sophisticatedly heterogeneous population of human umbilical vein endothelial cells2014
- Author(s)
  Zheng YW, Nie YZ, Tsuchida T, Zhang RR, Aoki K, Sekine K, Ogawa M, Takebe T, Ueno Y, Sakakibara H, Hirahara F, Taniguchi H
- Journal Title
  
  Transplant Proc
  
  Volume: 46 Issue: 4 Pages: 1251-3
- DOI
  10.1016/j.transproceed.2013.11.077
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-25461956, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Efficient hepatic differentiation of human induced pluripotent stem cells in a three-dimensional microscale culture.2014
- Author(s)
  Zhang RR, Takebe T, Miyazaki L, Takayama M, Koike H, Kimura M, Enomura M, Zheng YW, Sekine K, Taniguchi H.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1210 Pages: 131-141
- DOI
  10.1007/978-1-4939-1435-7_10
- ISBN
  9781493914340, 9781493914357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-26670585
[Journal Article] High-resolution intravital imaging for monitoring the transplanted islets in mice.2014
- Author(s)
  Takahashi Y, Takebe T, Enomura M, Koike N, Lee S, Nemeno JG, Sekine K, Lee JI, Taniguchi H.
- Journal Title
  
  Transplant Proc.
  
  Volume: 46 Issue: 4 Pages: 1166-1168
- DOI
  10.1016/j.transproceed.2013.11.089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24689052, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Tropism of cancer stem cells to a specific distant organ.2014
- Author(s)
  Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H.
- Journal Title
  
  In vivo.
  
  Volume: 28 Pages: 361-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305
[Journal Article] The CD133+CD44+ Precancerous Subpopulation of Oval Cells is a Therapeutic Target for Hepatocellular2014
- Author(s)
  Zheng YW, Tsuchida T, Shimao T, Li B, Takebe T, Zhang RR, Sakurai Y, Ueno Y, Sekine K, Ishibashi N, Imajima M, Tanaka T, Taniguchi H
- Journal Title
  
  Carcinoma Stem Cells Dev
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] Tropism of cancer stem cells to a specific distant organ2014
- Author(s)
  Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H.
- Journal Title
  
  In Vivo
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305
[Journal Article] Engineering of human hepatic tissue with functional vascular networks2014
- Author(s)
  Takebe T, Koike N, Sekine K, Fujiwara R, Amiya T, Zheng YW and Taniguchi H
- Journal Title
  
  Organogenesis
  
  Volume: 10(2)(Epub ahead of print) Issue: 2 Pages: 260-267
- DOI
  10.4161/org.27590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079, KAKENHI-PUBLICLY-26106721
[Journal Article] Identification of Proliferating Human Hepatic Cells from Human Induced Pluripotent Stem Cells2014
- Author(s)
  Zhang RR, Takebe T, Sekine K, Koike H, Zheng YW, Taniguchi H
- Journal Title
  
  Transplant Proc
  
  Volume: 46(4) Issue: 4 Pages: 1201-4
- DOI
  10.1016/j.transproceed.2013.12.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24689052, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] The CD133+CD44+ Precancerous Subpopulation of Oval Cells is a Therapeutic Target for Hepatocellular Carcinoma2014
- Author(s)
  Zheng YW, Tsuchida T, Shimao T, Li B, Takebe T, Zhang RR, Sakurai Y, Ueno Y, Sekine K, Ishibashi N, Imajima M, Tanaka T, Taniguchi H.
- Journal Title
  
  Stem Cells Dev.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] ヒト臓器の人為的構成に基づく肝細胞の分化誘導2014
- Author(s)
  15.武部貴則,関根圭輔,谷口英樹
- Journal Title
  
  ES・iPS細胞実験スタンダード―再生・創薬・疾患研究のプロトコールと臨床応用の必須知識―
  
  Volume: 0 Pages: 235-245
- Data Source
  KAKENHI-PROJECT-25253079
[Journal Article] Fluorescent labeling and visualization of human induced pluripotent stem cells with the use of transcription activator-like effector nucleases.2014
- Author(s)
  Sekine K, Takebe T, Taniguchi H.
- Journal Title
  
  Transplant Proc.
  
  Volume: 46 Issue: 4 Pages: 1205-1207
- DOI
  10.1016/j.transproceed.2014.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-26670585
[Journal Article] Fluorescent labeling and visualization of human induced pluripotent stem cells with the use of transcription activatore like effector nucleases2014
- Author(s)
  Sekine K, Takebe T, Taniguchi H.
- Journal Title
  
  Transplant Proc.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390305
[Journal Article] Ring1B promotes hepatic stem/ progenitor cell expansion via simultaneous suppression of Cdkn1a and Cdkn2a.2014
- Author(s)
  Koike H, Ueno Y, Naito T, Shiina T, Nakata S, Ouchi R, Obana Y, Sekine K, Zheng YW,Takebe T, Isono KI, Koseki H, Taniguchi H.
- Journal Title
  
  Hepatology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] Tropism of cancer stem cells to a specific distant organ2014
- Author(s)
  Okuda R, Sekine K, Hisamatsu D, Ueno Y, Takebe T, Zheng YW, Taniguchi H
- Journal Title
  
  In Vivo
  
  Volume: 28(3) Pages: 361-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] Ring1B Promotes Hepatic Stem/Progenitor Cell Expansion via Simultaneous Suppression of Cdkn1a and Cdkn2a.2014
- Author(s)
  Koike H, Ueno Y, Naito T, Shiina T, Nakata S, Ouchi R, Obana Y, Sekine K, Zheng YW, Takebe T, Isono K, Koseki H, Taniguchi H
- Journal Title
  
  Hepatology
  
  Volume: 印刷中 Issue: 1 Pages: 323-333
- DOI
  10.1002/hep.27046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-25460488, KAKENHI-PROJECT-25461956, KAKENHI-PUBLICLY-26106721, KAKENHI-PROJECT-26670585
[Journal Article] Engineering of human hepatic tissue with functional vascular networks.2014
- Author(s)
  Takebe T, Koike N, Sekine K, Fujiwara R, Amiya T, Zheng YW, Taniguchi H.
- Journal Title
  
  Organogenesis.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659593
[Journal Article] Vitamin D receptor in osteoblasts is a negative regulator of bone mass control2013
- Author(s)
  Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, Sekine K, Sato T, Kawano H, Aihara K, Naka michi Y, Watanabe T, Shindo M, Inoue K, Inoue E, Tsuji N, Hoshino M, Karsenty G, Metzger D, Chambon P, Kato S, Imai Y.
- Journal Title
  
  Endocrinology.
  
  Volume: 154 Issue: 3 Pages: 1008-20
- DOI
  10.1210/en.2012-1542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02106, KAKENHI-PROJECT-23591347, KAKENHI-PROJECT-23659712, KAKENHI-PROJECT-23689066, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24614004, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24780094, KAKENHI-PROJECT-25462905, KAKENHI-PUBLICLY-23132502
[Journal Article] Vascularized and functional human liver from an iPSC-derived organ bud transplant.2013
- Author(s)
  Takanori Takebe*, Keisuke Sekine, Masahiro Enomura, Hiroyuki Koike, Ran-Ran Zhang, Yasuharu Ueno, Yun-Wen Zheng, Naoto Koike, Shinsuke Aoyama, Yasuhisa Adachi, Hideki Taniguch*(*: Correspondence)
- Journal Title
  
  Nature
  
  Volume: 499 Issue: 7459 Pages: 481-484
- DOI
  10.1038/nature12271
- NAID
  40020351046
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24106510, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079, KAKENHI-PROJECT-25461956
[Journal Article] The generation of pancreatic β-cell spheroids in a simulated microgravity culture system.2013
- Author(s)
  Tanaka H
- Journal Title
  
  Biomaterials
  
  Volume: 34 Issue: 23 Pages: 5785-5791
- DOI
  10.1016/j.biomaterials.2013.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-22390260, KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-23659620, KAKENHI-PROJECT-23791490, KAKENHI-PUBLICLY-24106510, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PROJECT-25253079
[Journal Article] Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis2012
- Author(s)
  Hirose, Y., Saijou, E., Sugan,o Y., Takeshita, F., Nishimura, S., Nonaka, H., Chen, Y.R., Sekine, K., Kido, T., Nakamura, T., Kato, S., Kanke, T., Nakamura, K., Nagai, R., Ochiya, T., Miyajima, A.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 109 Issue: 11 Pages: 4263-4268
- DOI
  10.1073/pnas.1117560109
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21115008, KAKENHI-PROJECT-23689067, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659686
[Journal Article] Generation of functional human vascular network in vitro2012
- Author(s)
  Takebe T
- Journal Title
  
  Transplant Proc
  
  Volume: 44(4) Issue: 4 Pages: 1130-1133
- DOI
  10.1016/j.transproceed.2012.03.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-22390260, KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-23659620, KAKENHI-PROJECT-23791490, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PUBLICLY-24106510
[Journal Article] Self-organization of human hepatic organoid by recapitulating organogenesis in vitro2012
- Author(s)
  Takebe T
- Journal Title
  
  Transplant Pro
  
  Volume: 44(4) Issue: 4 Pages: 1018-1020
- DOI
  10.1016/j.transproceed.2012.02.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-22390260, KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-23659620, KAKENHI-PROJECT-23791490, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PUBLICLY-24106510
[Journal Article] Basics and applications of stem cells in the pancreas2012
- Author(s)
  Sekine K, Taniguchi H
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 19 Issue: 6 Pages: 594-599
- DOI
  10.1007/s00534-012-0545-3
- NAID
  10031126973
- Data Source
  KAKENHI-PROJECT-22390260, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593
[Journal Article] Establishment of Automated Culture System for Murine Induced Pluripotent Stem Cells2012
- Author(s)
  Koike H
- Journal Title
  
  BMC Biotechnology
  
  Volume: 12 Issue: 1 Pages: 81-81
- DOI
  10.1186/1472-6750-12-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-22390260, KAKENHI-PROJECT-23591872, KAKENHI-PROJECT-23659620, KAKENHI-PROJECT-23791490, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PUBLICLY-24106510
[Journal Article] Highly efficient generation of definitive endoderm lineage from human induced pluripotent stem cells2012
- Author(s)
  Sekine K
- Journal Title
  
  Transplant Proc
  
  Volume: 44(4) Issue: 4 Pages: 1127-1129
- DOI
  10.1016/j.transproceed.2012.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-23659620, KAKENHI-PROJECT-23689040, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-24106510, KAKENHI-PUBLICLY-24112505
[Journal Article] Regenerative medicine approach as an alternative treatment to islet transplantation.2012
- Author(s)
  Sekine K
- Journal Title
  
  Transplant Proc
  
  Volume: 44(4) Issue: 4 Pages: 1104-1106
- DOI
  10.1016/j.transproceed.2012.03.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249071, KAKENHI-PROJECT-24390305, KAKENHI-PROJECT-24659593, KAKENHI-PROJECT-24659785, KAKENHI-PROJECT-24689052, KAKENHI-PUBLICLY-24106510
[Journal Article] Reconstitution of hepatic tissue architectures from fetal liver cells obtained from a three-dimensional culture with a rotating wall vessel bioreactor.2011
- Author(s)
  Ishikawa M, Sekine K, Okamura A, Zheng YW, Ueno Y, Koike N, Tanaka J, Taniguchi H., equal contribution.
- Journal Title
  
  J Biosci Bioeng.
  
  Volume: (Article in Press)
- NAID
  110008672821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] Reconstitution of hepatic tissue architectures from fetal liver cells obtained from a three-dimensional culture with a rotating wall vessel bioreactor.2011
- Author(s)
  Ishikawa M, Sekine K, Okamura A, Zheng YW, Ueno Y, Koike N, Tanaka J, Taniguchi H.
- Journal Title
  
  J Biosci Bioeng. 111
  
  Pages: 711-718
- NAID
  110008672821
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] Multiple Biological Complex of Alkaline Extract of the Leaves of Sasa senanensis Rehder.2010
- Author(s)
  Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.
- Journal Title
  
  In Vivo 24
  
  Pages: 735-743
- NAID
  120005518460
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] Multiple Biological Complex of Alkaline Extract of the Leaves of Sasa senanensis Rehder.2010
- Author(s)
  Sakagami H, Zhou L, Kawano M, Thet MM, Tanaka S, Machino M, Amano S, Kuroshita R, Watanabe S, Chu Q, Wang QT, Kanamoto T, Terakubo S, Nakashima H, Sekine K, Shirataki Y, Zhang CH, Uesawa Y, Mohri K, Kitajima M, Oizumi H, Oizumi T.
- Journal Title
  
  In Vivo
  
  Volume: 240 Pages: 735-743
- NAID
  120005518460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] Y-Box Binding Protein-1 Down-Regulates Expression of Carbamoyl Phosphate Synthetase-I by Suppressing CCAAT Enhancer-Binding Protein-Alpha Function in Mice2009
- Author(s)
  Chen YR、関根圭輔、田中稔、宮島篤、その他2名
- Journal Title
  
  Gastroenterology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390467
[Journal Article] Mechanisms of resistance to interferon-gamma-mediated cell growth arrest in human oral squamous carcinoma cells.2009
- Author(s)
  Hiroi M, Mori K, Sekine K, Sakaeda Y, Shimada J, Ohmori Y.
- Journal Title
  
  J Biol Chem. 284
  
  Pages: 24869-24880
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] YB-1 downregulates expression of carbamoyl phosphate synthetase-I by suppressing C/EBPα function in mice2009
- Author(s)
  Chen YR, Sekine K, Nakamura K, Yanai Y, Tanaka M, Miyajima A.
- Journal Title
  
  Gastroenterology 137
  
  Pages: 330-340
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] YB-1 downregulates expression of carbamoyl phosphate synthetase 1 by suppressing C/EBPa function, leading to hyperammonemia2009
- Author(s)
  Chen Y-R., Sekine Ke., Nakamura, K., Yanai, H.Tanaka M., Miyajima A.
- Journal Title
  
  Gastroenterology 137
  
  Pages: 330-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014016
[Journal Article] A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function : enhanced transfection efficiency before and after differentiation.2009
- Author(s)
  Amano S, Sekine K, Bonewald LF, Ohmori Y.
- Journal Title
  
  J Cell Physiol. 221
  
  Pages: 40-53
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] YB-1 downregulates expression of carbamoyl phosphate synthetase-I by suppressing C/EBPαfunction in mice.2009
- Author(s)
  Chen YR, Sekine K, Nakamura K, Yanai Y, Tanaka M, Miyajima A.
- Journal Title
  
  Gastroenterology (in press)
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] YB-1 downregulates expression of carbamoyl phosphate synthetase 1 by suppressing C/EBPα function, leading to hyperammonemia.2009
- Author(s)
  Chen Y-R., Sekine Ke., Nakamura, K., Yanai, H. Tanaka M., Miyajima A.
- Journal Title
  
  Gastroenterology 137
  
  Pages: 330-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014016
[Journal Article] YB-1 downregulates expression of carbamoyl phosphate synthetase-I by suppressing C/EBP α function in mice.2009
- Author(s)
  Chen YR, Sekine K, Nakamura K, Yanai Y, Tanaka M, Miyajima A
- Journal Title
  
  Gastroenterology 137
  
  Pages: 330-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function : enhanced transfection efficiency before and after differentiation.2009
- Author(s)
  Amano S, Sekine K, Bonew ald LF, Ohmori Y
- Journal Title
  
  J Cell Physiol. 221
  
  Pages: 40-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791812
[Journal Article] A novel osteoclast precursor cell line, 4B12, recapitulates the features of primary osteoclast differentiation and function: enhanced transfection efficiency before and after differentiation.2009
- Author(s)
  Amano S, Sekine K, Bonewald LF, Ohmori Y.
- Journal Title
  
  J Cell Physiol. (in press)
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] YB-1 downregulates expression of carbamoyl phosphate synthetase-I by suppressing C/EBPa function in mice2009
- Author(s)
  Chen YR, Sekine K, Nakamura K, Yanai H, Tanaka M, Miyajima A
- Journal Title
  
  Gastroenterology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] 肝臓が糖代謝能を獲得するしくみ2008
- Author(s)
  関根圭輔, 他
- Journal Title
  
  メディカルバイオ 5
  
  Pages: 76-82
- NAID
  40015871411
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] Strain-dependent embryonic lethality and exaggerated vascular remodeling in heparin cofactor II-deficient mice.2007
- Author(s)
  Aihara K, Azuma H, Akaike M, Ikeda Y, Sata M,Takamori N, Yagi S, Iwase T, Sumitomo Y,Kawano H, Yamada T, Fukuda T, Matsumoto T,Sekine K, Sato T, Nakamichi Y, Yamamoto Y,Yoshimura K, Watanabe T, Nakamura T, OomizuA, Tsukada M, Hayashi H, Sudo T, Kato S,Matsumoto T
- Journal Title
  
  J Clin Invest. 117(6)
  
  Pages: 1514-1526
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] TRB2, a Mouse Tribbles Ortholog, Suppresses Adipocyte Differentiation by Inhibiting AKT and C/EBPbeta.2007
- Author(s)
  Naiki T, Saijou E, Miyaoka Y, Sekine K, Miyajima A.
- Journal Title
  
  J Biol Chem. 282(33)
  
  Pages: 24075-24082
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development.2007
- Author(s)
  Sekine K., et. al.
- Journal Title
  
  EMBO Journal 26
  
  Pages: 3607-3615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] Foxo1 links insulin signaling to C/EBPα and regulates gluconeogenesis during liver development.2007
- Author(s)
  Sekine K., Kojima N., Chen Y-R., Fukamizu A., Miyajima A.
- Journal Title
  
  EMBO J. 26
  
  Pages: 3607-3615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014016
[Journal Article] TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting Akt and C/EBPβ2007
- Author(s)
  Naiki T., Saijou E., Sekine K., Miyajima A.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 24075-24082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014016
[Journal Article] Foxo1 links insulin signaling to C/EBPalpha and regulates glucoeogenesis during liver development.2007
- Author(s)
  Sekine K, Chen YR, Kojima N, Ogata K, Fukamizu A, Miyajima A.
- Journal Title
  
  EMBO J. 26(15)
  
  Pages: 3607-3615
- Data Source
  KAKENHI-PROJECT-19791371
[Journal Article] Neuronal leucine-rich repeat protein 4 is required for hippocampus-dependent long-lasting memory.2005
- Author(s)
  Bando T., Sekine K., Kobayashi S., Watanabe A., Rump A., Tanaka M., Suda Y., Kato S., Manabe T., Miyajima A.
- Journal Title
  
  Mol. Cell Biol. 25
  
  Pages: 4166-4175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014016
[Patent] 多能性幹細胞からの立体臓器の構築2020
- Inventor(s)
  谷口英樹、武部貴則、関根圭輔
- Industrial Property Rights Holder
  谷口英樹、武部貴則、関根圭輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-557347
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 未分化細胞の分化抵抗性評価法2020
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 未分化細胞の分化抵抗性評価法2020
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 多能性幹細胞からの立体臓器の構築2020
- Inventor(s)
  谷口英樹、武部貴則、関根圭輔
- Industrial Property Rights Holder
  谷口英樹、武部貴則、関根圭輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-557347
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 未分化細胞検出法2019
- Inventor(s)
  関根圭輔、谷口英樹、安居良太
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、安居良太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-207002
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 上皮間葉転換関連分子を用いた癌評価法2019
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 再構成癌組織を用いた薬剤評価方法2019
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 未分化マーカー遺伝子高感度検出法2019
- Inventor(s)
  関根圭輔、谷口英樹、安居良太、松井貴香
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、安居良太、松井貴香
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-207004
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 未分化細胞の分化抵抗性評価法2019
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-005892
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 上皮間葉転換関連分子を用いた癌評価法2019
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 未分化細胞検出法2019
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 未分化細胞の分化抵抗性評価法2019
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-005892
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-15KK0314
[Patent] 未分化マーカー遺伝子高感度検出法2019
- Inventor(s)
  関根圭輔、谷口英樹、安居良太、松井貴香
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、安居良太、松井貴香
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-207004
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 未分化細胞検出法2019
- Inventor(s)
  関根圭輔、谷口英樹、安居良太
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、安居良太
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-207002
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 未分化細胞検出法2019
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 再構成癌組織を用いた薬剤評価方法2019
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03718
[Patent] 再構成癌組織を用いた薬剤評価方法2018
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-080585
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15KK0314
[Patent] 未分化細胞検出法2018
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-115025
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 上皮間葉転換関連分子を用いた癌評価法2018
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-080581
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 再構成癌組織を用いた薬剤評価方法2018
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-080585
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K19589
[Patent] 未分化細胞検出法2018
- Inventor(s)
  関根圭輔、谷口英樹
- Industrial Property Rights Holder
  関根圭輔、谷口英樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-115025
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15KK0314
[Patent] 上皮間葉転換関連分子を用いた癌評価法2018
- Inventor(s)
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Holder
  関根圭輔、谷口英樹、上野康晴、奥田諒、森永聡一郎、宮城洋平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-080581
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-15KK0314
[Patent] 癌微小環境を再現できる癌組織の再構築法2016
- Inventor(s)
  谷口英樹、関根圭輔、上野康晴、奥田諒、武部貴則
- Industrial Property Rights Holder
  谷口英樹、関根圭輔、上野康晴、奥田諒、武部貴則
- Industrial Property Rights Type
  特許
- Filing Date
  2016-03-16
- Data Source
  KAKENHI-PROJECT-15H04922
[Patent] 癌微小環境を再現できる癌組織の再構築法2016
- Inventor(s)
  谷口英樹、関根圭輔、上野康晴、奥田諒、武部貴則
- Industrial Property Rights Holder
  谷口英樹、関根圭輔、上野康晴、奥田諒、武部貴則
- Industrial Property Rights Type
  特許
- Filing Date
  2016-03-16
- Data Source
  KAKENHI-PROJECT-26670585
[Patent] 血液細胞を用いた組織・臓器の作製方法2015
- Inventor(s)
  谷口英樹、武部貴則、関根圭輔、鄭允文、聶運中
- Industrial Property Rights Holder
  谷口英樹、武部貴則、関根圭輔、鄭允文、聶運中
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-24
- Data Source
  KAKENHI-PROJECT-15H04922
[Patent] 血液細胞を用いた組織・臓器の作製方法2015
- Inventor(s)
  谷口英樹、武部貴則、関根圭輔、鄭允文、聶運中
- Industrial Property Rights Holder
  谷口英樹、武部貴則、関根圭輔、鄭允文、聶運中
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-24
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] がん三次元培養モデルを用いた膵癌組織細胞間相互作用の解明2024
- Author(s)
  関根圭輔
- Organizer
  第113回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] がん三次元培養モデルを用いた膵癌組織細胞間相互作用の解明2024
- Author(s)
  関根圭輔
- Organizer
  第113回日本病理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] Elucidation and Control of Cancer Ecosystem using Artificial Cancer Tissue2022
- Author(s)
  Keisuke Sekine
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] Recapitulating pancreatic cancer ecosystems by multicellular cancer organoid cultures.2022
- Author(s)
  関根圭輔
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] がん研究入門コース(新技術)「オルガノイドを用いたがん研究」2022
- Author(s)
  関根圭輔
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] がん三次元培養モデルを用いた膵癌組織細胞間相互作用の解明2022
- Author(s)
  関根圭輔
- Organizer
  第4回がん三次元培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] Elucidation and Control of Cancer Ecosystem using Artificial Cancer Tissue2022
- Author(s)
  Keisuke Sekine
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] 患者由来癌モデルを用いたがんエコシステム解明2022
- Author(s)
  関根圭輔
- Organizer
  日本患者由来がんモデル学会2022学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] Recapitulating pancreatic cancer ecosystems by multicellular cancer organoid cultures.2022
- Author(s)
  Keisuke Sekine
- Organizer
  AACR2022 Annual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] Recapitulating pancreatic cancer ecosystems by multicellular cancer organoid cultures.2022
- Author(s)
  Keisuke Sekine
- Organizer
  AACR2022 Annual Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] 人為的がんモデルを用いたがん細胞社会の解明2022
- Author(s)
  関根圭輔
- Organizer
  第8回細胞凝集研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24400
[Presentation] がん三次元培養モデルを用いた膵癌組織細胞間相互作用の解明2022
- Author(s)
  関根圭輔
- Organizer
  第4回がん三次元培養研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] がん研究入門コース(新技術)「オルガノイドを用いたがん研究」2022
- Author(s)
  関根圭輔
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] ⼈為的がんモデルを⽤いたがん細胞社会の解明2022
- Author(s)
  関根圭輔
- Organizer
  第8回細胞凝集研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] 患者由来癌モデルを用いたがんエコシステム解明2022
- Author(s)
  関根圭輔
- Organizer
  日本患者由来がんモデル学会2022学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19575
[Presentation] がんオルガノイドを用いたゲノム編集とその可能性2021
- Author(s)
  関根圭輔
- Organizer
  第11回がん新薬開発合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] がんエコシステム解明に向けた患者由来癌モデルの構築2021
- Author(s)
  関根圭輔
- Organizer
  講演会：新しい治療法の開発を目指す患者由来がんモデル
- Invited
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] Multicellular cancer organoid recapitulating cancer ecosystem using patient-derived pancreatic cancer cells2021
- Author(s)
  関根圭輔
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] Elucidation and control of cancer ecosystem using artificial cancer tissue.2020
- Author(s)
  Keisuke Sekine
- Organizer
  The 79th Annual Meeting of the Japanese Cancer Association
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] Multicellular cancer organoid cultures for recapitulating cancer ecosystems2019
- Author(s)
  Keisuke Sekine
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] Generation of three-dimensional cancer tissue using patient-derived pancreatic cancer cells2019
- Author(s)
  Keisuke Sekine
- Organizer
  Asia-Pacific Scientific Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] Multicellular cancer organoid cultures for recapitulating cancer ecosystems2019
- Author(s)
  Keisuke Sekine
- Organizer
  The 78th Annual Meeting of the Japanese Cancer Association
- Invited
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] Generation of three-dimensional cancer tissue using patient-derived pancreatic cancer cells2019
- Author(s)
  Keisuke Sekine
- Organizer
  Asia-Pacific Scientific Workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] Recapitulating pancreatic cancer ecosystems by multicellular cancer organoid cultures based on patient-derived cancer cells2019
- Author(s)
  関根圭輔
- Organizer
  患者由来がんモデル
- Invited
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] Generation of human liver using iPS cells for regenerative therapies2019
- Author(s)
  Keisuke Sekine
- Organizer
  American Association for the Study of Liver Diseases(AASLD)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] Generation of functional human liver from pluripotent stem cell.2019
- Author(s)
  Keisuke Sekine
- Organizer
  26th East Asia Joint Symposium on Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] Generation of functional human liver from pluripotent stem cell.2019
- Author(s)
  Keisuke Sekine
- Organizer
  26th East Asia Joint Symposium on Biomedical Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] Recapitulating pancreatic cancer ecosystems by multicellular cancer organoid cultures based on patient-derived cancer cells2019
- Author(s)
  関根圭輔
- Organizer
  患者由来がんモデル
- Invited
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] Generation of human liver using iPS cells for regenerative therapies2019
- Author(s)
  Keisuke Sekine
- Organizer
  American Association for the Study of Liver Diseases(AASLD)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03718
[Presentation] 再生医療応用へ向けたiPSC肝芽製造技術の開発2018
- Author(s)
  関根圭輔
- Organizer
  幹細胞の培養法・培養工学のためのコンソーシアム　第三回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 患者由来膵癌細胞を用いた三次元的癌組織の人為的創出2018
- Author(s)
  関根圭輔
- Organizer
  講演会：新しい治療法の開発を目指す患者由来がんモデル
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] ヒト組織三次元的再構成技術を用いたヒューマンバイオロジーの解析2018
- Author(s)
  関根圭輔
- Organizer
  第11回Symphony
- Invited
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] ヒト組織三次元的再構成技術を用いたヒューマンバイオロジーの解析2018
- Author(s)
  関根圭輔
- Organizer
  第11回Symphony
- Invited
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] ヒトiPSC肝芽の臨床応用に向けた安全性評価手法の確立2018
- Author(s)
  濱田侑希、関根圭輔、都築周作、小林達也、上野康晴、武部貴則、谷口英樹
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 再生医療応用へ向けたiPSC肝芽製造技術の開発2018
- Author(s)
  関根圭輔
- Organizer
  幹細胞の培養法・培養工学のためのコンソーシアム　第三回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] ヒトiPSC肝芽の臨床応用に向けた安全性評価手法の確立2018
- Author(s)
  濱田侑希、関根圭輔、都築周作、小林達也、上野康晴、武部貴則、谷口英樹
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 患者由来膵癌細胞を用いた三次元的癌組織の人為的創出2018
- Author(s)
  関根圭輔
- Organizer
  講演会：新しい治療法の開発を目指す患者由来がんモデル
- Invited
- Data Source
  KAKENHI-PROJECT-18K19589
[Presentation] ヒトiPSC肝芽の臨床応用に向けた安全性評価手法の確立2018
- Author(s)
  濱田侑希、関根圭輔、都築周作、小林達也、上野康晴、武部貴則、谷口英樹
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 血管化膵島移植による革新的糖尿病治療の確立2017
- Author(s)
  高橋禎暢、武部貴則、小池直人、関根圭輔、谷口英樹
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] 血管化膵島移植による革新的糖尿病治療法の確立2017
- Author(s)
  高橋禎暢、武部貴則、小池直人、関根圭輔、谷口英樹
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター(宮城)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 腫瘍微小環境を伴う膵癌オルガノイドは薬剤耐性を示す2017
- Author(s)
  碓井彩華、奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、井上達也、金子千夏、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 腫瘍微小環境を伴う膵癌オルガノイドはin vitroで治療抵抗性を示す2017
- Author(s)
  金子千夏、奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、井上達也、碓井彩華、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 血管化膵島移植による革新的糖尿病治療法の確立2017
- Author(s)
  高橋禎暢、武部貴則、小池直人、関根圭輔、谷口英樹
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター(宮城)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 癌微小環境を模倣した患者由来ヒト膵がんオルガノイドの創出2017
- Author(s)
  奥田諒、関根圭輔、上野康晴康晴、佐藤準也、高橋正希、井上達也、金子千夏、碓井彩華、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 微小環境を伴うヒト膵オルガノイドの再構成に基づく新規膵癌薬剤評価系の構築2017
- Author(s)
  上野康晴、奥田諒、金子千夏、碓井彩華、関根圭輔、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 微小環境を伴うヒト膵オルガノイドの再構成に基づく新規膵癌薬剤評価系の構築2017
- Author(s)
  上野康晴、奥田諒、金子千夏、碓井彩華、関根圭輔、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドは薬剤耐性を示す2017
- Author(s)
  関根圭輔、奥田諒、井上達也、金子千夏、碓井彩華、上野康晴、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 血管化膵島移植による革新的糖尿病治療法の確立2017
- Author(s)
  高橋禎暢、武部貴則、小池直人、関根圭輔、谷口英樹
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター(宮城)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドは薬剤耐性を示す2017
- Author(s)
  関根圭輔、奥田諒、井上達也、金子千夏、碓井彩華、上野康晴、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 腫瘍微小環境を伴う膵癌オルガノイドはin vitroで治療抵抗性を示す2017
- Author(s)
  金子千夏、奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、井上達也、碓井彩華、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 血管化膵島移植による革新的糖尿病治療の確立2017
- Author(s)
  高橋禎暢、武部貴則、小池直人、関根圭輔、谷口英樹
- Organizer
  第44回日本膵・膵島移植研究会
- Place of Presentation
  芝蘭会館（京都府京都市）
- Year and Date
  2017-03-10
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドは薬剤耐性を示す2017
- Author(s)
  関根圭輔、奥田諒、井上達也、金子千夏、碓井彩華、上野康晴、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 腫瘍微小環境を伴う膵癌オルガノイドは薬剤耐性を示す2017
- Author(s)
  碓井彩華、奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、井上達也、金子千夏、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 癌微小環境を模倣した患者由来ヒト膵がんオルガノイドの創出2017
- Author(s)
  奥田諒、関根圭輔、上野康晴康晴、佐藤準也、高橋正希、井上達也、金子千夏、碓井彩華、谷口英樹 / 横浜市大・医・臓器再生医学
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 癌微小環境を模倣した患者由来ヒト膵がんオルガノイドの創出2017
- Author(s)
  奥田諒、関根圭輔、上野康晴康晴、佐藤準也、高橋正希、井上達也、金子千夏、碓井彩華、谷口英樹 / 横浜市大・医・臓器再生医学
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 腫瘍微小環境を伴う膵癌オルガノイドは薬剤耐性を示す2017
- Author(s)
  碓井彩華、奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、井上達也、金子千夏、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 腫瘍微小環境を伴う膵癌オルガノイドはin vitroで治療抵抗性を示す2017
- Author(s)
  金子千夏、奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、井上達也、碓井彩華、谷口英樹
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 臓器形成におけるヘテロジェネイティの理解と制御2016
- Author(s)
  武部貴則、関根圭輔、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドの創出2016
- Author(s)
  奥田諒、高橋正希、佐藤準也、関根圭輔、上野康晴、谷口英樹
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] シングルセルRNAシークエンスによるiPS細胞由来肝細胞のポピュレーション解析2016
- Author(s)
  関根圭輔、J. Gray Camp、Barbara Treutlein、武部貴則、谷口英樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] シングルセルRNAシークエンスによるiPS細胞由来肝細胞のポピュレーション解析2016
- Author(s)
  関根圭輔, J.Gray Camp,Barbara Treutlein, 武部貴則,谷口英樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドの創出2016
- Author(s)
  奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、濱中香織、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] Generation of functional human liver from pluripotent stem cell2016
- Author(s)
  Keisuke Sekine, Takanori Takebe, Hideki Taniguchi
- Organizer
  German Association for the Study of the Liver (GASL) workshop
- Place of Presentation
  Dusseldorf(ドイツ)
- Year and Date
  2016-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] De novo generation of organ buds from stem cells2016
- Author(s)
  Keisuke Sekine
- Organizer
  21st NAT Congress
- Place of Presentation
  Nantes, France
- Year and Date
  2016-06-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] シングルセルレベルでのiPSC肝芽構成細胞のポピュレーションヘテロジェネイティ解析2016
- Author(s)
  関根圭輔、J. Gray Camp、Barbara Treutlein、武部貴則、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドの創出2016
- Author(s)
  奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、濱中香織、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] シングルセルRNAシークエンスによるiPS細胞由来肝細胞のポピュレーション解析2016
- Author(s)
  関根圭輔、J. Gray Camp、Barbara Treutlein、武部貴則、谷口英樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] De novo generation of organ buds from stem cells2016
- Author(s)
  Keisuke Sekine
- Organizer
  21st NAT Congress
- Place of Presentation
  Nantes, France
- Year and Date
  2016-06-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] Generation of functional human liver from pluripotent stem cell2016
- Author(s)
  Keisuke Sekine, Takanori Takebe, Hideki Taniguchi
- Organizer
  German Association for the Study of the Liver (GASL) workshop
- Place of Presentation
  Dusseldorf(ドイツ)
- Year and Date
  2016-01-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドの創出2016
- Author(s)
  奥田諒、高橋正希、佐藤準也、関根圭輔、上野康晴、谷口英樹
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] De novo generation of organ buds from stem cells2016
- Author(s)
  Keisuke Sekine
- Organizer
  21st NAT Congress
- Place of Presentation
  Nantes, France
- Year and Date
  2016-06-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 血管化膵島移植による革新的糖尿病治療法の確立2016
- Author(s)
  高橋禎暢,武部貴則,小池直人, 関根圭輔,谷口英樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] 臓器形成におけるヘテロジェネイティの理解と制御2016
- Author(s)
  武部貴則、関根圭輔、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] ヒト膵癌オルガノイドを用いた新規薬剤評価系の構築2016
- Author(s)
  濱中香織,上野康晴,奥田諒,関根圭輔,倉田昌直,宮城洋平,森永総一郎,横瀬智之,遠藤格,谷口英樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] シングルセルレベルでのiPSC肝芽構成細胞のポピュレーションヘテロジェネイティ解析2016
- Author(s)
  関根圭輔、J. Gray Camp、Barbara Treutlein、武部貴則、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] Development of a human pancreatic cancer organoid recapitulating the tumor microenvironment.2016
- Author(s)
  Taniguchi H, Sekine K, Okuda R, Ueno Y
- Organizer
  The 41st Naito Conference, Cancer Heterogenecity and Plasticity: Relevance to Therapeutic Resistance
- Place of Presentation
  シャトレーゼガトーキングダム（北海道札幌市）
- Year and Date
  2016-07-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] シングルセルレベルでのiPSC肝芽構成細胞のポピュレーションヘテロジェネイティ解析2016
- Author(s)
  関根圭輔、J. Gray Camp、Barbara Treutlein、武部貴則、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K15597
[Presentation] 膵癌の微小環境を有する膵癌オルガノイドの創出2016
- Author(s)
  佐藤準也, 奥田諒, 濱中香織, 高橋正希,関根圭輔, 上野康晴,谷口英樹
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドの創出2016
- Author(s)
  奥田諒、関根圭輔、上野康晴、佐藤準也、高橋正希、濱中香織、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] 腫瘍微小環境を模倣するヒト膵癌オルガノイドの創出2016
- Author(s)
  奥田諒、高橋正希、佐藤準也、関根圭輔、上野康晴、谷口英樹
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、神奈川
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 臓器形成におけるヘテロジェネイティの理解と制御2016
- Author(s)
  武部貴則、関根圭輔、谷口英樹
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15KK0314
[Presentation] Metastatic tropism of pancreatic cancer stem cells to a specific distant organ.2015
- Author(s)
  Ryo Okuda, Keisuke Sekine, Kaori Hamanaka, Hideki Taniguchi.
- Organizer
  The Biology of Cancer: Microenvironment, Metastasis & Therapeutics
- Place of Presentation
  New York (米国)
- Year and Date
  2015-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] 膵癌幹細胞の転移における特定臓器への指向性2015
- Author(s)
  泉陽彦、竹歳卓人、関根圭輔、奥田諒、濱中香織、谷口英樹
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] iPS細胞を用いた代謝性臓器の再生医療2015
- Author(s)
  関根圭輔
- Organizer
  第30回日本整形外科学会基礎学術総会
- Place of Presentation
  富山市民プラザ(富山県富山市)
- Year and Date
  2015-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] iPS細胞を用いた代謝性臓器の再生医療2015
- Author(s)
  武部貴則、関根圭輔、谷口英樹
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] iPS細胞を用いた代謝性臓器の再生医療2015
- Author(s)
  関根圭輔
- Organizer
  第30回日本整形外科学会基礎学術総会
- Place of Presentation
  富山市民プラザ(富山県富山市)
- Year and Date
  2015-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] Pdx1+ cells behave as pancreatic cancer stem cells with high tumorigenicity and metastatic potential2015
- Author(s)
  Ryo Okuda, Keisuke Sekine, Lue Sun , Kaori Hamanaka, Hideki Taniguchi
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] Pdx1+ cells behave as pancreatic cancer stem cells with high tumorigenicity and metastatic potential2015
- Author(s)
  Ryo Okuda, Keisuke Sekine, Lue Sun , Kaori Hamanaka, Hideki Taniguchi
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] A novel system with human liver features for screening anti-hepatitis B virus therapeutics2015
- Author(s)
  Nie YZ,Zheng YW,kZhang RR,Tsuchida T,Ueno Y、Sekine K,Takebe T,Taniguchi H
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2015-03-20
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵癌転移における微小環境と癌幹細胞の相互作用の解析2015
- Author(s)
  濱中香織、奥田諒、関根圭輔、谷口英樹
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Metastatic tropism of pancreatic cancer stem cells to a specific distant organ.2015
- Author(s)
  Ryo Okuda, Keisuke Sekine, Kaori Hamanaka, Hideki Taniguchi.
- Organizer
  The Biology of Cancer: Microenvironment, Metastasis & Therapeutics
- Place of Presentation
  New York (米国)
- Year and Date
  2015-05-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04922
[Presentation] 膵癌幹細胞の系譜解析に向けたin vitroアッセイ系の構築2014
- Author(s)
  久松大介、奥田　諒、関根圭輔、上野康晴、谷口英樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] iPS細胞を用いた代謝性臓器の創出技術開発拠点2014
- Author(s)
  谷口英樹、武部貴則、関根圭輔、鄭　允文、上野康晴
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Invited
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] ヒトiPS細胞の肝細胞分化誘導プロトコルの至適化2014
- Author(s)
  大鐘ひなつ、武部貴則、小池博之、川又史佳、木村昌樹、関根圭輔、谷口英樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] ヒトiPS細胞由来臓器原基移植による機能的なヒト肝臓の創出2014
- Author(s)
  武部貴則、関根圭輔、谷口英樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Invited
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] Identification of pancreatic cancer stem cell lineage during pancreatic tumorigenesis2014
- Author(s)
  奥田諒、関根圭輔、久松大介、孫略、濵中香織、谷口英樹
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] ヒトiPSC由来肝細胞スフェア大量創出法の開発2014
- Author(s)
  宮崎令奈、武部貴則、高山真秀、木村昌樹、小池博之、江野村允宏、川又史佳、関根圭輔、谷口英樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] 膵癌幹細胞の系譜解析に向けたin vitroアッセイ系の構築2014
- Author(s)
  久松大介、奥田　諒、関根圭輔、上野康晴、谷口英樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  国立京都国際会館(京都府)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵癌幹細胞の系譜解析に向けたin vitroアッセイ系の構築2014
- Author(s)
  久松大介、奥田諒、関根圭輔、上野康晴、谷口英樹
- Organizer
  第13回日本再生医療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] スフィア形成能を有する膵癌幹細胞の解析2014
- Author(s)
  久松大介、奥田諒、関根圭輔、濵中香織、上野康晴、谷口英樹
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 遺伝子改変モデル動物を用いた膵癌幹細胞の機能解析2014
- Author(s)
  関根圭輔、奥田諒、久松大介、濱中香織、谷口英樹
- Organizer
  第41回日本臓器保存生物医学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2014-11-28
- Invited
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Identification and characterization of Pdx1+ pancreatic cancer stem cell during pancreatic tumorigenesis2014
- Author(s)
  関根圭輔、奥田諒、久松大介、谷口英樹
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] ヒト微小血管網を有する膵島様組織の創出2013
- Author(s)
  高橋禎暢、武部貴則、江野村允宏、田中博康、小池直人、関根圭輔、谷口英樹
- Organizer
  第40回日本臓器保存生物医学会学術集会
- Place of Presentation
  東京医科大学病院臨床講堂（東京都）
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] Pdx1陽性細胞は高い腫瘍形成能とスフィア形成能を有する癌幹細胞である2013
- Author(s)
  奥田諒、関根圭輔、孫略、坪井康次、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] ヒト膵癌幹細胞における治療抵抗性機構の解析2013
- Author(s)
  星野小百合、関根圭輔、孫略、中田晋、寺崎哲也、森永総一郎、宮城洋平、遠藤格、横瀬智之、倉田昌直、上野康晴、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Pdx1陽性細胞は高い腫瘍形成能とスフィア形成能を有する癌幹細胞である2013
- Author(s)
  奥田諒、関根圭輔、孫略、坪井康次、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Flow cytometric identification and characterization of endothelial progenitor cells in human umbilical vein endothelial cells.2013
- Author(s)
  Zheng YW, Aoki K, Tsuchida T, Zhang R, Sekine K, Ogawa M, Takebe T, Yasumura K, Ueno Y, Sakakibara H, Hiranaka F, Taniguchi H
- Organizer
  The 13th Congress of the Asian Society of Transplantation.
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] Targeted proteomic absolute quantification on transporters of human pancreatic cancer cells with gemcitabine-resistance.2013
- Author(s)
  Ueno Y, Hoshino S, Tsuchida N, Nakata S, Uchida Y, Sekine K, Zheng YW, Kurata M, Morinaga S, Miyagi Y, Yokose T, Endo I, Terasaki T, Hirano H, Taniguchi H
- Organizer
  HUPO 12th annual world congress.
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Targeted proteomic absolute quantification on transporters of human pancreatic cancer cells with gemcitabine-resistance.2013
- Author(s)
  Ueno Y, Hoshino S, Tsuchida N, Nakata S, Uchida Y, Sekine K, Zheng YW, Kurata M, Morinaga S, Miyagi Y, Yokose T, Endo I, Terasaki T, Hirano H, Taniguchi H
- Organizer
  HUPO 12th annual world congress.
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Creation of vascularized and functional human liver from an induced pluripotent stem cell-derived organ bud transplant.2013
- Author(s)
  Takebe T, Sekine K, Enomura M, Koike H, Zhang R, Kimura M, Ogaeri T, Yoshizawa E, Kawamata F, Koike N, Ueno Y, Zheng YW, Taniguchi H
- Organizer
  The 13th Congress of the Asian Society of Transplantation.
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] Targeted proteomic absolute quantification on transporters of human pancreatic cancer cells with gemcitabine-resistance2013
- Author(s)
  Ueno Y, Hoshino S, Tsuchida N, Nakata S, Uchida Y, Sekine K, Zheng YW, Kurata M, Morinaga S, Miyagi Y, Yokose T, Endo I, Terasaki T, Hirano H, Taniguchi H
- Organizer
  HUPO 12th annual world congress
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵幹/前駆細胞の膵癌幹細胞への形質転換プロセスの解析2013
- Author(s)
  関根圭輔、孫略、奥田諒、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Fluorescence visualizaiton of human induced pluripotent stem cells using transcription activator-like(TAL) effector nucleases2013
- Author(s)
  Sekine K, Takebe T, Zhang R, Taniguchi H
- Organizer
  The 13th Congress of the Asian Society of Transplantation
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Fluorescence visualizaiton of human induced pluripotent stem cells using transcription activator-like(TAL) effector nucleases.2013
- Author(s)
  Sekine K, Takebe T, Zhang R, Taniguchi H
- Organizer
  The 13th Congress of the Asian Society of Transplantation.
- Place of Presentation
  国立京都国際会館（京都府）
- Data Source
  KAKENHI-PROJECT-25253079
[Presentation] Pdx1陽性細胞は高い腫瘍形成能とスフィア形成能を有する癌幹細胞である2013
- Author(s)
  奥田諒、関根圭輔、孫略、坪井康次、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] ヒト膵癌幹細胞における治療抵抗性機構の解析2013
- Author(s)
  12. 星野小百合、関根圭輔、孫略、中田晋、寺崎哲也、森永総一郎、宮城洋平、遠藤格、横瀬智之、倉田昌直、上野康晴、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵幹/前駆細胞の膵癌幹細胞への形質転換プロセスの解析2013
- Author(s)
  関根圭輔、孫略、奥田諒、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] ヒト膵癌幹細胞における治療抵抗性機構の解析2013
- Author(s)
  星野小百合、関根圭輔、孫略、中田晋、寺崎哲也、森永総一郎、宮城洋平、遠藤格、横瀬智之、倉田昌直、上野康晴、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵幹/前駆細胞の膵癌幹細胞への形質転換プロセスの解析2013
- Author(s)
  関根圭輔、孫略、奥田諒、谷口英樹
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] ヒト微小血管網を有する膵島様組織の創出2012
- Author(s)
  高橋禎暢、江野村允宏、武部貴則、関根圭輔、小池直人、田中寛康、谷口英樹
- Organizer
  第39回日本臓器保存生物医学会学術集会
- Place of Presentation
  コラッセふくしま(福島県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Self-renewal versus differentiation as well as the liver repopulation capability of human hepatic stem cells.2012
- Author(s)
  Zheng Y, Li B, Zhang R, Kimura M, Tsuchida T, Takebe T, Ueno Y, Sekine K, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10^<th> annual meeting
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Identification of pancreatic stem/progenitor cells expres sing PDX1 reside in the CD133 positive pancreatic due2012
- Author(s)
  Sekine K, Ishikawa M, Takebe T, Suzaki A, Kawashimo K, Matsui C, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10^<th> annual meeting.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] ヒト微小血管網を有する膵島様組織の創出2012
- Author(s)
  高橋禎暢, 江野村允宏, 武部貴則, 関根圭輔, 小池直人, 田中寛康, 谷口英樹
- Organizer
  第39回日本臓器保存生物医学会学術集会
- Place of Presentation
  コラッセふくしま(福島県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 多能性幹細胞を用いた機能的なヒト臓器の創出2012
- Author(s)
  武部貴則、関根圭輔、江野村允宏、小池博之、張冉冉、木村昌樹、魚返拓則、吉澤絵美、川又史佳、上野康晴、鄭允文、小池直人、谷口英樹
- Organizer
  第39回日本臓器保存生物医学会学術集会
- Place of Presentation
  コラッセふくしま(福島県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵肝/前駆細胞の膵癌幹細胞への形質転換プロセスの解析2012
- Author(s)
  孫略、奥田諒、関根圭輔、盛武敬、坪井康次、谷口英樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌 (北海道)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵癌モデルマウスを用いた膵癌幹細胞の細胞系譜解析2012
- Author(s)
  関根圭輔、孫略、奥田諒、谷口英樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌 (北海道)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵幹細胞を起点とした膵発癌プロセスにおける膵癌幹細胞の細胞系譜的解析2012
- Author(s)
  関根圭藍, 孫略, 上野康晴, 谷口英樹
- Organizer
  第22回日本サイトメトリー学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2012-06-30
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Creation of vascularized human organ from induced piuripotent stem cells.2012
- Author(s)
  Takebe T, Sekine K, Enomura M, Suzuki Y, Koike H, Zhang R, Koike N, Ueno Y, Zheng Y, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10^<th> annual meeting
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] ヒトiPSを用いたファーマコセロミクス基盤技術の開発2012
- Author(s)
  谷口英樹, 武部貴則, 関根圭輔, 青山晋輔, 安達弥永
- Organizer
  第127回日本薬理学会関東部会シンポジウム
- Place of Presentation
  東京国際フォーラム(東京)(招待講演)
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Self-renewal versus differentiation as well as the liver repopulation capability of human hepatic stem cells.2012
- Author(s)
  Zheng Y, Li B, Zhang R, Kimura M, Tsuchida T, Takebe T, Ueno Y, Sekine K, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10th annual meeting.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Identification of pancreatic stem/progenitor cells expressing PDX1 reside in the CD133 positive pancreatic duct.2012
- Author(s)
  Sekine K, Ishikawa M, Takebe T, Suzaki A, Kawashimo K, Matsui C, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10th annual meeting.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Identification of pancreatic stem/progenitor cells expres sing PDX1 reside in the CD133 positive pancreatic duet.2012
- Author(s)
  Sekine K, Ishikawa M, Takebe T, Suzaki A, Kawashimo K, Matsui C, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10^<th> annual meeting.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 多能性幹細胞を用いた機能的なヒト臓器の創出2012
- Author(s)
  武部貴則, 関根圭輔, 江野村允宏, 小池博之, 張冉冉, 三橋優澄, 上野康晴, 鄭允文, 谷口英樹
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] Generation of islet like structures with human functional vascular networks.2012
- Author(s)
  Enomura M, Takebe T, Sekine K, Koike N, Taniguchi H, Tanaka H
- Organizer
  International Society for Stem Cell Research 10^<th> annual meeting
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵癌幹細胞のin vitroアッセイ系の解析2012
- Author(s)
  奥田諒, 孫略, 関根圭輔, 松井智栄美, 坪井康次, 谷口英樹
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 多能性幹細胞を用いた機能的なヒト臓器の創出2012
- Author(s)
  武部貴則, 関根圭輔, 江野村允宏, 小池博之, 張冉冉, 木村昌樹, 魚返拓則, 吉澤絵美, 川又史佳, 上野康晴, 鄭允文, 小池直人, 谷旦英樹
- Organizer
  第39回日本臓器保存生物医学会学術集会
- Place of Presentation
  コラッセふくしま(福島県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵肝/前駆細胞の膵癌幹細胞への形質転換プロセスの解析2012
- Author(s)
  孫略, 奥田諒, 関根圭輔, 盛武敬, 坪井康次, 谷口英樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵肝/前駆細胞の膵癌幹細胞への形質転換プロセスの解析2012
- Author(s)
  関根圭輔、孫略、奥田諒、谷口英樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵幹細胞を起点とした膵発癌プロセスの細胞系譜的解析2012
- Author(s)
  関根圭輔、松井智栄美、孫略、長久紗耶佳、田中慎、武部貴則、谷口英樹
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Creation of vascularized human organ from induced pluripotent stem cells.2012
- Author(s)
  Takebe T, Sekine K, Enomura M, Suzuki Y, Koike H, Zhang R, Koike N, Ueno Y, Zheng Y, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10th annual meeting.
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵癌モデルマウスを用いた膵癌幹細胞の細胞系譜解析2012
- Author(s)
  孫略、奥田諒、関根圭輔、盛武敬、坪井康次、谷口英樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 多能性幹細胞を用いた機能的なヒト臓器の創出2012
- Author(s)
  武部貴則、関根圭輔、江野村允宏、小池博之、張冉冉、三橋優澄、上野康晴、鄭允文、谷口英樹
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵幹細胞を起点とした膵発癌プロセスの細胞系譜的解析2012
- Author(s)
  関根圭輔, 松井智栄美, 孫略, 長久紗耶佳, 田中慎, 武部貴則, 谷口英樹
- Organizer
  第11回日本再生医療学会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵癌幹細胞のin vitroアッセイ系の解析2012
- Author(s)
  奥田諒、孫略、関根圭輔、松井智栄美、坪井康次、谷口英樹
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Identification of pancreatic stem/progenitor cells expressing PDX1 reside in the CD133 positive pancreatic duct2012
- Author(s)
  Sekine K, Ishikawa M, Takebe T, Suzaki A, Kawashimo K, Matsui C, Taniguchi H
- Organizer
  International Society for Stem Cell Research 10^<th> annual meeting
- Place of Presentation
  Yokohama,Japan
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵癌モデルマウスを用いた膵癌幹細胞の細胞系譜解析2012
- Author(s)
  関根圭輔, 孫略, 奥田諒, 谷口英樹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(札幌)
- Data Source
  KAKENHI-PROJECT-24390305
[Presentation] 膵癌幹細胞のin vitroアッセイ系の解析2012
- Author(s)
  奥田諒、孫略、関根圭輔、松井智栄美、坪井康次、谷口英樹
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 破骨細胞分化における内因性 Wnt シグナルの役割2011
- Author(s)
  天野滋、関根圭輔、大森喜弘
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  長良川国際会議場
- Year and Date
  2011-10-01
- Data Source
  KAKENHI-PROJECT-22592047
[Presentation] 転写因子Pdx1の可視化による膵幹/前駆細胞の選択的分離と特性解析2010
- Author(s)
  関根圭輔, 石川桃太郎, 松井智栄美, 須崎敦大, 川下金明, 大島祐二, 鄭允文, 谷口英樹
- Organizer
  日本バイオイメージング学会
- Place of Presentation
  慶應義塾大学日吉キャンパス(横浜)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21791812
[Presentation] 血管ネットワークを有したヒト肝組織の生体内再構築系の確立2010
- Author(s)
  関根圭輔, 藤原綾二, 小池直人, 千葉豊生, Dai Fukumura, Rakesh K.Jain, 上野康晴, 鄭允文, 谷口英樹
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21791812
[Presentation] Regulation of pRb but not p53 by IFNgamma in Human Oral Squamous Cell Carcinoma2009
- Author(s)
  Sekine K, Ohmori Y.
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21791812
[Presentation] Regulation of pRb but not p53 by IFNgamma in Human Oral Spuamous Cell Carcinoma2009
- Author(s)
  Sekine K, Ohmori Y.
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21791812
[Presentation] 2008年口腔癌細胞増殖抑制におけるインターフェロンγシグナルの解析2008
- Author(s)
  関根圭輔, 廣井美紀, 大森喜弘
- Organizer
  第50回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19791371
[Presentation] 破骨細胞前駆細胞株4B12細胞への遺伝子導入効率2008
- Author(s)
  天野滋, 関根圭輔, 大森喜弘
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19791371
[Presentation] 2008年破骨細胞前駆細胞株4B12細胞への遺伝子導入効率2008
- Author(s)
  天野滋, 関根圭輔, 大森喜弘
- Organizer
  第50回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19791371
[Presentation] 口腔癌細胞増殖抑制におけるインターフェロンγシグナルの解析2008
- Author(s)
  関根圭輔, 廣井美紀, 大森喜弘
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  東京
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19791371
[Presentation] 2007年破骨細胞分化に関する核内リン酸化蛋白質の2次元電気泳動解析2007
- Author(s)
  天野滋, 関根圭輔, 廣井美紀, 大森喜弘
- Organizer
  第49回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-19791371
[Presentation] Identification and characterization of Pdx1+ pancreatic cancer stem cell during pancreatic tumorigenesis
- Author(s)
  関根圭輔、奥田諒、久松大介、谷口英樹
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] iPS細胞を用いた代謝性臓器の再生医療
- Author(s)
  武部貴則、関根圭輔、谷口英樹
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2015-03-19 – 2015-03-21
- Invited
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] 膵癌転移における微小環境と癌幹細胞の相互作用の解析
- Author(s)
  濱中香織、奥田諒、関根圭輔、谷口英樹
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] スフィア形成能を有する膵癌幹細胞の解析
- Author(s)
  久松大介、奥田諒、関根圭輔、濵中香織、上野康晴、谷口英樹
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] 膵幹細胞を起点とした膵発癌プロセスにおける膵癌幹細胞の細胞系譜的解析
- Author(s)
  関根圭輔、孫略、上野康晴、谷口英樹
- Organizer
  第22 回日本サイトメトリー学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Invited
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] 膵癌幹細胞の転移における特定臓器への指向性
- Author(s)
  泉陽彦、竹歳卓人、関根圭輔、奥田諒、濱中香織、谷口英樹
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] ヒトiPSを用いたファーマコセロミクス基盤技術の開発
- Author(s)
  谷口英樹、武部貴則、関根圭輔、青山晋輔、安達弥永
- Organizer
  第127回日本薬理学会関東部会シンポジウム
- Place of Presentation
  東京国際フォーラム(東京都)
- Invited
- Data Source
  KAKENHI-PROJECT-24659593
[Presentation] Identification of pancreatic cancer stem cell lineage during pancreatic tumorigenesis
- Author(s)
  奥田諒、関根圭輔、久松大介、孫略、濵中香織、谷口英樹
- Organizer
  The 73rd Annual Meeting of the Japanese Cancer Association.
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] A novel system with human liver features for screening anti-hepatitis B virus therapeutics
- Author(s)
  Nie YZ,Zheng YW,kZhang RR,Tsuchida T,Ueno Y、Sekine K,Takebe T,Taniguchi H
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-26670585
[Presentation] 遺伝子改変モデル動物を用いた膵癌幹細胞の機能解析
- Author(s)
  関根圭輔、奥田諒、久松大介、濱中香織、谷口英樹
- Organizer
  第41回日本臓器保存生物医学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2014-11-28 – 2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26670585

1. MIYAJIMA Atsushi (50135232)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. TANAKA Minoru (80321909)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. TANIGUCHI Hideki (70292555)

# of Collaborated Projects: 4 results

# of Collaborated Products: 80 results
4. TAKEBE Takanori (20612625)

# of Collaborated Projects: 4 results

# of Collaborated Products: 60 results
5. OHMORI Yshihiro (50194311)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. ITOH Tohru (50396917)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TANIMIZU Naoki (00333386)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. AMANO Shigeru (90167958)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. SAIJIO Eiko (60376647)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. HANAZAWA Shigemasa (60060258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MASUHIRO Yoshikazu (00336083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIROI Miki (30419717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小池直人 (50301081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
14. 海野研二 (00969230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 平岡伸介 (40276217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 青木一教 (60270675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 木戸丈友 (00401034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉田健一 (50738226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 谷田部恭 (90280809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. CAMP J. Gray

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. TREUTLEIN Barbara

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. UENO Yasuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
23. YU T.-y

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 竹下文隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 鄭允文

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
26. 米谷達哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 折舘伸彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 佐野大佑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 高橋秀聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sekine Keisuke 関根 圭輔

SEKINE Keisuke 関根 圭輔

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Spatiotemporal interactions in metastatic nichesPrincipal Investigator

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Development of organoid gene analysis system elucidating individual differences in cancer.Principal Investigator

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Elucidation of the metastasis mechanism by constructing a metastasis modelPrincipal Investigator

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Elucidation and control of pancreatic cancer-stroma interaction by artificial cancer tissue constructionPrincipal Investigator

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Semi-exhaustive functional screening of cell-cell interaction factors in human iPSC mini-liverPrincipal Investigator

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Cell lineage analysis of changes in characteristics of pancreatic cancer cells at single cell level(Fostering Joint International Research)Principal Investigator

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Single cell heterogeneity analysis of endothelial and mesenchymal cellsPrincipal Investigator

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Dissecting pancreatic cancer cell evolution at single cell level.Principal Investigator

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Visualization of functional hepatic cells derived from human iPS cells.Principal Investigator

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Sekine Keisuke 関根圭輔

SEKINE Keisuke 関根圭輔