Shiroishi Mitsunori 白石充典

… Alternative Names

SHIROISHI Mitsunori 白石充典

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Researcher Number	00380527
Other IDs
Affiliation (Current)	2025: 東京理科大学, 先進工学部生命システム工学科, 教授
Affiliation (based on the past Project Information) *help	2021: 東京理科大学, 先進工学部生命システム工学科, 准教授 2019 – 2020: 東京理科大学, 基礎工学部生物工学科, 准教授 2014 – 2017: 九州大学, 薬学研究院, 助教 2011 – 2016: 九州大学, 薬学研究科(研究院), 助教 2015: 九州大学, 大学院薬学研究科, 助教 … More 2013: 九州大学, 大学院・薬学研究院, 助教 2012: 九州大学, 大学院・薬学研究科, 助教 2010 – 2012: 九州大学, 薬学研究院, 助教 2011: 九州大学, 大学院・薬学研究院, 助教 2011: 九州大学, 薬学研究科, 助教 2009: 京都大学, 医学研究科, 研究員 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Basic Section 43020:Structural biochemistry-related / Biofunction/Bioprocess Except Principal Investigator General medical chemistry / Laboratory medicine / Applied pharmacology / Chemistry related to living body / Pain science / Structural biochemistry
Keywords	Principal Investigator G蛋白質共役型受容体 / タンパク質工学 / Gタンパク質共役型受容体 / 構造解析 / 結晶構造解析 / 分子認識 / 自己抗体 / リウマトイド因子 / 膜タンパク質 / 抗原 … More / 蛋白質工学 / 生物機能工学 / 膜蛋白質 / 大量調製 / 安定化 / 出芽酵母 / ヒスタミン受容体 / 機能解析 … More Except Principal Investigator 抗体 / 蛋白質 / Fab / 蛋白質工学 / X線結晶構造解析 / 安定化 / 抗体工学 / P2X4受容体 / 神経障害性疼痛 / 構造解析 / GPCR / 膜タンパク質 / 痛み / モノクローナル抗体 / P2X4 / 薬理学 / イメージング / 痛みの定量 / 安定性 / 免疫学 / Derp2 / Anti-Drug Antibodies / immunolgy / stability / antibody / アンジオテンシン受容体 / 構造認識抗体 / X線結晶構造 / アンジオテンシン / 膜蛋白質 / Gタンパク質共役受容体 / デアミデーション / アミノ酸変異 / 抗体医薬品 / 蛋白質の劣化 / ヒト型Fab / アミノ酸改変 / in Silicoスクリーニング / 共結晶 / 結晶化 / 構造生物 / Mhp1 / X線結晶構造解 / 交互アクセス機構 / 交互アクセスモデル / トランスポーター / ヒダントイン / 輸送体 / X線結晶解析 Less

Elucidation of the molecular recognition of stereotype rheumatoid factor.Principal Investigator
- Principal Investigator
  
  Shiroishi Mitsunori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Tokyo University of Science
Creation of the membrane-protein-particle antigen for the effective production of a crystallization-facilitator antibodyPrincipal Investigator
- Principal Investigator
  
  Shiroishi Mitsunori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
Fundamental Study on Preparations for Therapeutic Antibodies with Less Productions of Anti-Drug Antibodies
- Principal Investigator
  
  Ueda Tadashi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyushu University
Establishment of research foundation on "objective pain assessment" using animal models suffering from neuropathic pain
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyushu University
Crystallization of Angiotensin receptor type 2 with its specific antibody
- Principal Investigator
  
  Asada Hidetsugu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Development of the strategy for creating stabilized GPCR variants for large-scale preparationPrincipal Investigator
- Principal Investigator
  
  Shiroishi Mitsunori
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Kyushu University
Study on the development of molecules for depressing neuropathic pain based on tertiary structure of human P2X4 receptor
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pain science
- Research Institution
  Kyushu University
Development of Fab molecule with the stable scaffold for next generation
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Chemistry related to living body
- Research Institution
  Kyushu University
Elucidating of inhibition mechanism of anti-histamines for the histamine receptor by X-ray crystallography.Principal Investigator
- Principal Investigator
  
  SHIROISHI Mitsunori
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
Crystallization of GPCR and its specific antibody
- Principal Investigator
  
  ASADA Hidetsugu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
Elucidation of the transport mechanism of a secondary active transporter, Mhp1.
- Principal Investigator
  
  SHIMAMURA Tatsuro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyoto University

All 2022 2021 2020 2019 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions2022
- Author(s)
  Shinozaki Chinatsu、Kohno Keita、Shiroishi Mitsunori、Takahashi Daisuke、Yoshikawa Yu、Abe Yoshito、Hamase Kenji、Nakakido Makoto、Tsumoto Kohei、Inoue Kazuhide、Tsuda Makoto、Ueda Tadashi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 131-131
- DOI
  10.1038/s41598-021-03784-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06514, KAKENHI-PROJECT-21K06517, KAKENHI-PROJECT-20H02531
[Journal Article] Structural Basis of a Conventional Recognition Mode of IGHV1-69 Rheumatoid Factors.2020
- Author(s)
  Shiroishi M.
- Journal Title
  
  Adv Exp Med Biol.
  
  Volume: - Pages: 1-12
- DOI
  10.1007/5584_2020_510
- ISBN
  9783030678135, 9783030678142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06514
[Journal Article] Structural and Functional Basis for LILRB Immune Checkpoint Receptor Recognition of HLA-G Isoforms2019
- Author(s)
  Kuroki Kimiko、Matsubara Haruki、Kanda Ryo、Miyashita Naoyuki、Shiroishi Mitsunori、Fukunaga Yuko、Kamishikiryo Jun、Fukunaga Atsushi、Fukuhara Hideo、Hirose Kaoru、Hunt Joan S.、Sugita Yuji、Kita Shunsuke、Ose Toyoyuki、Maenaka Katsumi
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Issue: 12 Pages: 3386-3394
- DOI
  10.4049/jimmunol.1900562
- NAID
  120007018379
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06073, KAKENHI-PROJECT-19K06514, KAKENHI-PROJECT-18KK0194, KAKENHI-PROJECT-19H00918, KAKENHI-PROJECT-17K07296, KAKENHI-PUBLICLY-19H04634
[Journal Article] Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae2016
- Author(s)
  Shiroishi M, Moriya M, Ueda T
- Journal Title
  
  Protein Science
  
  Volume: 25 Issue: 10 Pages: 1863-1872
- DOI
  10.1002/pro.2993
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25709080
[Journal Article] Structural Analysis of the Histamine H1 Receptor2016
- Author(s)
  Shiroishi M, Kobayashi T
- Journal Title
  
  Handbook of experimental pharmacology.
  
  Volume: 印刷中 Pages: 21-30
- DOI
  10.1007/164_2016_10
- ISBN
  9783319581927, 9783319581941
- Data Source
  KAKENHI-PROJECT-25709080
[Journal Article] Screening of stable G-protein-coupled receptor variants in Saccharomyces cerevisiae.2015
- Author(s)
  Shiroishi M, Kobayashi T.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1261 Pages: 159-70
- DOI
  10.1007/978-1-4939-2230-7_9
- ISBN
  9781493922291, 9781493922307
- Data Source
  KAKENHI-PROJECT-25709080
[Journal Article] Proteoliposome-based selection of a recombinant antibody fragment against the human M2 muscarinic acetylcholine receptor.2014
- Author(s)
  Suharni, Nomura Y, Arakawa T, Hino T, Abe H, Nakada-Nakura Y, Sato Y, Iwanari H, Shiroishi M, Asada H, Shimamura T, Murata T, Kobayashi T, Hamakubo T, Iwata S, Nomura N.
- Journal Title
  
  Monoclon Antib Immunodiagn Immunother
  
  Volume: 33 Issue: 6 Pages: 378-385
- DOI
  10.1089/mab.2014.0041
- NAID
  120005530933
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PROJECT-25220205, KAKENHI-PROJECT-25650023, KAKENHI-PROJECT-25709080, KAKENHI-PUBLICLY-26102725
[Journal Article] The long-term immunosuppressive effects of disulfide-linked HLA-G dimer in mice with collagen-induced arthritis.2013
- Author(s)
  Kuroki Kら
- Journal Title
  
  Hum Immunol.
  
  Volume: 74 Issue: 4 Pages: 433-438
- DOI
  10.1016/j.humimm.2012.11.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370043, KAKENHI-PROJECT-23770102, KAKENHI-PROJECT-24249016, KAKENHI-PROJECT-24659215, KAKENHI-PROJECT-25709080
[Journal Article] 出芽酵母（S. cerevisiae）を用いた高発現・安定化GPCR改変体の作製と評価2013
- Author(s)
  白石充典
- Journal Title
  
  蛋白質科学会アーカイブ
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25709080
[Journal Article] Strategies for the structural determination of G protein-coupled receptors: from an example of histamine H1 receptor2013
- Author(s)
  Mitsunori Shiroishi
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 未定
- NAID
  130003361947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Strategies for the Structural Determination of G Protein-coupled Receptors: From an Example of Histamine H1 Receptor2013
- Author(s)
  Shiroishi M
- Journal Title
  
  Yakugaku Zasshi
  
  Volume: 133 Pages: 539-547
- NAID
  130003361947
- Data Source
  KAKENHI-PROJECT-25709080
[Journal Article] Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharomyces cerevisiae2012
- Author(s)
  Shiroishi M*, Tsujimoto H, Makyio H, Asada H, Yurugi-Kobayashi T, Shimamura T, Murata T, Nomura N, Haga T, Iwata S* Kobayashi T*
- Journal Title
  
  Microb Cell Fact.
  
  Volume: 11 Pages: 78-78
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharoroyces cerevisiae.2012
- Author(s)
  Shiroishi M., et al.
- Journal Title
  
  Micorb, Cell Fact.
  
  Volume: 11 Issue: 1 Pages: 78-78
- DOI
  10.1186/1475-2859-11-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23370049, KAKENHI-PROJECT-23657074, KAKENHI-PROJECT-23770123, KAKENHI-PROJECT-24370044, KAKENHI-PROJECT-24659132, KAKENHI-PUBLICLY-24121715
[Journal Article] Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist2012
- Author(s)
  Haga, K*., A. C. Kruse*,H. Asada*, T. Yurugi-Kobayashi, M. Shiroishi, C. Zhang, W. I. Weis, T. Okada, B. K. Kobilka, T. Haga, and T. Kobayashi
- Journal Title
  
  These authors contributed equally to this work
  
  Volume: 482 Pages: 547-551
- NAID
  120003752107
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist2012
- Author(s)
  Haga K., et al
- Journal Title
  
  Nature
  
  Volume: 482 Issue: 7386 Pages: 547-551
- DOI
  10.1038/nature10753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J40150, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-22659059, KAKENHI-PROJECT-23370049
[Journal Article] Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.2012
- Author(s)
  Haga K, Kruse AC, Asada H, Yurugi-Kobayashi T, Shiroishi M, Zhang C, Weis WI, Okada T, Kobilka BK, Haga T, Kobayashi T
- Journal Title
  
  Nature
  
  Volume: 482 Pages: 547-551
- NAID
  120003752107
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Production of the stable human histamine H1 receptor in Pichia pastoris for structural determination.2011
- Author(s)
  Shiroishi M, Kobayashi T, Ogasawara S, Tsujimoto H, Ikeda-Suno C, Iwata S, Shimamura T.
- Journal Title
  
  Methods
  
  Volume: 55 Pages: 281-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor.2011
- Author(s)
  de Graaf C, Kooistra AJ, Vischer HF, Katritch V, Kuijer M, Shiroishi M, Iwata S, Shimamura T, Stevens RC, de Esch IJ, Leurs R.
- Journal Title
  
  J Med Chem.
  
  Volume: 54 Pages: 8195-8206
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Molecular Basis for Herpesvirus Entry Mediator Recognition by the Human Immune Inhibitory Receptor CD160 and Its Relationship to the Cosignaling Molecules BTLA and LIGHT.2011
- Author(s)
  Kojima R, Kajikawa M, Shiroishi M, Kuroki K, Maenaka K.
- Journal Title
  
  J Mol Biol.
  
  Volume: 413 Pages: 762-772
- NAID
  120003660598
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Production of the stable human histamine H1 receptor in Pichia pastoris for structural determination2011
- Author(s)
  Shiroishi M, Kobayashi T, Ogasawara S, Tsujimoto H, Ikeda-Suno C, Iwata S, Shimamura T.
- Journal Title
  
  Methods
  
  Volume: 55 Pages: 281-286
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium2011
- Author(s)
  Tokuda, N., K. Igarashi, T. Shimamura, T. Yurugi-Kobayashi, M. Shiroishi, K. Ito, T. Sugawara, H. Asada, T. Murata, N. Nomura, S. Iwata, and T. Kobayashi
- Journal Title
  
  Protein Expr Purif
  
  Volume: 79 Pages: 81-87
- NAID
  120003255719
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor.2011
- Author(s)
  de Graaf C, Kooistra AJ, Vischer HF, Katritch V, Kuijer M, Shiroishi M, Iwata S, Shimamura T, Stevens RC, de Esch IJ, Leurs R.
- Journal Title
  
  J. Med. Chem.
  
  Volume: 54 Pages: 8195-8206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Production of the stable human histamine H(1) receptor in Pichia pastoris for structural determination2011
- Author(s)
  Shiroishi M, Kobayashi T, Shimamura T., et al
- Journal Title
  
  Methods
  
  Volume: 55 Issue: 4 Pages: 281-286
- DOI
  10.1016/j.ymeth.2011.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-23657074
[Journal Article] Production of the stable human histamine H(1) receptor in Pichia pastoris for structural determination2011
- Author(s)
  Shiroishi M, Kobayashi T, Ogasawara S, Tsujimoto H, Ikeda-Suno C, Iwata S, Shimamura T.
- Journal Title
  
  Methods.
  
  Volume: 55(4) Pages: 281-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043
[Journal Article] Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis.2011
- Author(s)
  Asada H, Uemura T, Yurugi-Kobayashi T, Shiroishi M, Shimamura T, Tsujimoto H, Ito K, Sugawara T, Nakane T, Nomura N, Murata T, Haga T, Iwata S, Kobayashi T.
- Journal Title
  
  Microb Cell Fact.
  
  Pages: 10-24
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Production of the stable human histamine H1 receptor in Pichia pastoris for structural determination2011
- Author(s)
  Shiroishi, M, T. Kobayashi, S. Ogasawara, H. Tsujimoto, C. Ikeda-Suno, S. Iwata, T. Shimamura
- Journal Title
  
  Methods
  
  Volume: 55 Pages: 281-286
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis2011
- Author(s)
  Asada, H., T. Uemura, T. Yurugi-Kobayashi, M. Shiroishi, T. Shimamura, H. Tsujimoto, K. Ito, T. Sugawara, T. Nakane, N. Nomura, T. Murata, T. Haga, S. Iwata, and T. Kobayashi
- Journal Title
  
  Microb Cell Fact
  
  Volume: 10 Pages: 24-24
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Molecular Basis for Herpesvirus Entry Mediator Recognition by the Human Immune Inhibitory Receptor CD160 and Its Relationship to the Cosignaling Molecules BTLA and LIGHT2011
- Author(s)
  Kojima R, M. Kajikawa, M. Shiroishi, K. Kuroki, K. Maenaka
- Journal Title
  
  J Mol Biol
  
  Volume: 413 Pages: 762-772
- NAID
  120003660598
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Structure of the human histamine H(1) receptor complex with doxepin.2011
- Author(s)
  Shimamura T*, Shiroishi M*, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S.
- Journal Title
  
  Nature
  
  Volume: 475 Pages: 65-70
- NAID
  120004225543
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis2011
- Author(s)
  Asada, H., Uemura, T., Yurugi-Kobayashi, T., Shiroishi, M., Shimamura, T., Tsujimoto, H., Ito, K., Sugawara, T., Nakane, T., Nomura, N., Murata, T., Haga, T., Iwata, S., Kobayashi, T
- Journal Title
  
  Microbial Cell Factories
  
  Volume: 10 Issue: 1 Pages: 24-24
- DOI
  10.1186/1475-2859-10-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04341, KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270
[Journal Article] Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium2011
- Author(s)
  Tokuda N, Igarashi K, Shimamura T(co-1st author), Yurugi-Kobayashi T, Shiroishi M, Ito K, Sugawara T, Asada H, Murata T, Nomura N, Iwata S, Kobayashi T.
- Journal Title
  
  Protein. Expr. Purif.
  
  Volume: 79(1) Issue: 1 Pages: 81-7
- DOI
  10.1016/j.pep.2011.04.006
- NAID
  120003255719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370043, KAKENHI-PROJECT-22570114, KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23657074
[Journal Article] Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: case of a nonglycosylated mutant of miraculin, a taste-modifying protein2011
- Author(s)
  Ito, K., T. Sugawara, A. Koizumi, K.Nakajima, A. Shimizu-Ibuka, M. Shiroishi, H. Asada, T. Yurugi-Kobayashi, T. Shimamura, T. Asakura, T. Misaka, S. Iwata, T. Kobayashi, and K. Abe
- Journal Title
  
  Biotechnol Lett
  
  Volume: 33 Pages: 103-107
- NAID
  120002723145
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Structure of the human histamine H(1) receptor complex with doxepin, These authors contributed equally to this work2011
- Author(s)
  Shimamura T*, M. Shiroishi *, S. Weyand, H. Tsujimoto, G. Winter, V. Katritch, R. Abagyan, V. Cherezov, W. Liu, GW. Han, T. Kobayashi, RC. Stevens, S. Iwata
- Journal Title
  
  Nature
  
  Volume: 475 Pages: 65-70
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor2011
- Author(s)
  de Graaf C, AJ. Kooistra, HF. Vischer, V. Katritch, M. Kuijer, M. Shiroishi, S. Iwata, T. Shimamura, RC. Stevens, IJ. de Esch, R. Leurs
- Journal Title
  
  J Med Chem
  
  Volume: 54 Pages: 8195-8206
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion : case of a nonglycosylated mutant of miraculin, a taste-modifying protein2011
- Author(s)
  Ito, K., T.Sugawara, A.Koizumi, K.Nakajima, A.Shimizu-Ibuka, M.Shiroishi, H.Asada, T.Yurugi-Kobayashi, T.Shimamura, T.Asakura, T.Misaka, S.Iwata, T.Kobayashi, K.Abe
- Journal Title
  
  Biotechnology Letters
  
  Volume: Vol.33 Issue: 1 Pages: 103-107
- DOI
  10.1007/s10529-010-0399-1
- NAID
  120002723145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590270, KAKENHI-PROJECT-23248058
[Journal Article] Cloning, expression and purification of the anion exchanger 1 homologue from the basidiomycete Phanerochaete chrysosporium.2011
- Author(s)
  Tokuda N, Igarashi K, Shimamura T, Yurugi-Kobayashi T, Shiroishi M, Ito K, Sugawara T, Asada H, Murata T, Nomura N, Iwata S, Kobayashi T.
- Journal Title
  
  Protein Expr Purif.
  
  Volume: 79 Pages: 81-87
- NAID
  120003255719
- Data Source
  KAKENHI-PROJECT-23770123
[Journal Article] Contribution of asparagine residues to the stabilization of a proteinaceous antigen-antibody complex, HyHEL-10-hen egg white lysozyme2010
- Author(s)
  Yokota A, K. Tsumoto, M. Shiroishi, T. Nakanishi, H. Kondo, I. Kumagai
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 7686-96
- Data Source
  KAKENHI-PROJECT-22590270
[Journal Article] Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin2010
- Author(s)
  Ito, K., T. Sugawara, A. Koizumi, K. Nakajima, A. Shimizu-Ibuka, M. Shiroishi, H. Asada, T. Yurugi-Kobayashi, T. Shimamura, T. Asakura, K. Masuda, M. Ishiguro, T. Misaka, S. Iwata, T. Kobayashi, and K. Abe
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1800 Pages: 986-992
- Data Source
  KAKENHI-PROJECT-22590270
[Presentation] リウマトイド因子RF-TS1 Fv-claspの大量調製と評価2021
- Author(s)
  西崎恵菜美、白石充典
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06514
[Presentation] Fv-clasp化したリウマトイド因子YES8cの大量調製と評価2021
- Author(s)
  山本真瑠人、船田涼馬、瀧亮太、白石充典
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06514
[Presentation] Preparation and crystallization of Fv-clasp of the rheumatoid factor RF-TS12020
- Author(s)
  西崎恵菜美，白石充典
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06514
[Presentation] Saccharomyces cerevisiaeを用いた膜蛋白質安定化改変体作製・評価システムのハイスループット化とその有効性の検証2016
- Author(s)
  白石充典, 森谷真衣, 植田正
- Organizer
  第40回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Place of Presentation
  鹿児島県指宿市
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] Saccharomyces cerevisiaeを用いたケモカイン受容体CCR5の大量調製系の確立2016
- Author(s)
  松原直紀, 白石充典, 植田正
- Organizer
  第１６回日本蛋白質科学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-15K14460
[Presentation] Saccharomyces cerevisiaeにおける哺乳類由来GPCRの発現2016
- Author(s)
  白石充典, 松原直紀, 森谷真衣, 中野祐毅, 小林拓也, 岩田想, 植田正
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] Saccharomyces cerevisiae発現系による微小スケールでの膜蛋白質安定化変異体の評価～アデノシンA2A受容体を例に～2016
- Author(s)
  白石充典, 森谷真衣, 植田正
- Organizer
  第１６回日本蛋白質科学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] Saccharomyces cerevisiaeにおける哺乳類由来GPCRの発現2016
- Author(s)
  白石充典, 松原直紀, 森谷真衣, 中野祐毅, 小林拓也, 岩田想, 植田正
- Organizer
  第８９回日本生化学会大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-15K14460
[Presentation] Saccharomyces cerevisiaeを用いたケモカイン受容体CCR5の大量調製系の確立2016
- Author(s)
  松原直紀, 白石充典, 植田正
- Organizer
  第１６回日本蛋白質科学会年会
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] 高難度膜蛋白質の迅速な安定化のための酵母を用いた微小ハイスループットスクリーニングシステム2015
- Author(s)
  白石充典、森谷真衣、植田正
- Organizer
  BMB2015
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14460
[Presentation] 膜蛋白質の大量調製に向けた出芽酵母（S. cerevisiae）の利用；GPCRを例に2015
- Author(s)
  白石充典
- Organizer
  第15回蛋白質科学会年会
- Place of Presentation
  徳島県徳島市
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] 高難度膜蛋白質の大量調製に向けた安定化改変体の微小ハイスループットスクリーニング系の構築2015
- Author(s)
  白石充典、森谷真衣、中野裕毅、植田正
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  徳島市
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-15K14460
[Presentation] 高難度膜蛋白質の大量調製に向けた安定化改変体の微小ハイスループットスクリーニング系の構築2015
- Author(s)
  白石充典、森谷真衣、中野裕毅、植田正
- Organizer
  第15回蛋白質科学会年会
- Place of Presentation
  徳島県徳島市
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] 高難度膜蛋白質の迅速な安定化のための酵母を用いた微小ハイスループットスクリーニングシステム2015
- Author(s)
  白石充典、森谷真衣、植田正
- Organizer
  BMB2015
- Place of Presentation
  神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] アデノシンA2A受容体-リガンド相互作用の等温滴定型カロリメーターによる脂質二重膜中での解析に向けた試み2015
- Author(s)
  森谷真衣、小林拓也、岩田想、植田正、白石充典
- Organizer
  第15回蛋白質科学会年会
- Place of Presentation
  徳島県徳島市
- Year and Date
  2015-06-24
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] Protein engineering for mass production of integral membrane proteins; the case of G-protein coupled receptors2014
- Author(s)
  Mitsunori Shiroishi
- Organizer
  Korea-Japan Smart Biodesign Workshop: Technology exchange for green biotechnology
- Place of Presentation
  Sendai
- Invited
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014
- Author(s)
  永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、津田誠、井上和秀、阿部義人、植田正
- Organizer
  日本生化学会九州支部会
- Place of Presentation
  九州大学コラボステーションI
- Year and Date
  2014-05-18
- Data Source
  KAKENHI-PROJECT-26293129
[Presentation] P2X4 受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014
- Author(s)
  永井咲妃, 白石充典, 井川達弘, 斎藤秀俊, 山下智大, 津田誠, 井上和秀, 阿部義人, 植田正
- Organizer
  平成26年度日本生化学会九州支部会
- Place of Presentation
  九州大学コラボステーション I(福岡市)
- Year and Date
  2014-05-18
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立2014
- Author(s)
  永井咲妃, 白石充典, 井川達弘, 斎藤秀俊, 山下智大, 津田誠, 井上和秀, 阿部義人, 植田正
- Organizer
  平成26年度日本生化学会九州支部会
- Place of Presentation
  九州大学病院地区コラボステーションI（福岡市）
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] P2X4受容体細胞外ドメイン認識抗体の蛍光ゲルろ過法によるスクリーニング系の確立2014
- Author(s)
  永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、津田誠、井上和秀、阿部義人、植田正
- Organizer
  第25回クロマトグラフィー会議（京都）
- Place of Presentation
  京都大学（桂キャンパス）船井哲良記念講堂
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-26293129
[Presentation] ヒスタミンH1受容体の構造解明と抗ヒスタミン薬選択性の検証2014
- Author(s)
  白石充典
- Organizer
  第1回生命分子科学研究会
- Place of Presentation
  ニセコ町（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] 免疫反応を制御する受容体の構造および分子認識に関する研究2013
- Author(s)
  白石充典
- Organizer
  日本生化学会九州支部例会
- Place of Presentation
  佐賀大学（佐賀県）
- Invited
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] GPCRの構造研究に向けた迅速な改変体作製プラットフォーム2013
- Author(s)
  白石充典
- Organizer
  第3回　産と学をつなぐSENRIの会
- Place of Presentation
  千里ライフサイエンスセンタービル
- Invited
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] NMRを用いたラットP2X4受容体ヘッドドメインと金属イオンとの相互作用解析2013
- Author(s)
  井川達彦, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
- Organizer
  第日本蛋白質科学会
- Place of Presentation
  とりぎん会館（鳥取市）
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] NMR を用いたラットP2X4 受容体ヘッドドメインと金属イオンとの相互作用解析2013
- Author(s)
  井川達弘, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
- Organizer
  第13回日本蛋白質科学会
- Place of Presentation
  とりぎん会館(鳥取市)
- Year and Date
  2013-06-12
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] 出芽酵母を用いたGPCR改変体作製・評価システムの高度化と新規ターゲットへの応用2013
- Author(s)
  白石充典
- Organizer
  研究加速リトリート
- Place of Presentation
  淡路夢舞台（兵庫県）
- Invited
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] NMR を用いたラットP2X4受容体headドメインの構造決定およびリガンド相互作用解析2012
- Author(s)
  井川達弘, 阿部義人, 白石充典, 津田誠,井上和秀, 植田正
- Organizer
  第85回日本生化学会
- Place of Presentation
  福岡国際会議場・マリンメッセ(福岡市)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] GPCRの構造研究に向けた高発現・安定化改変体作製プラットフォーム2012
- Author(s)
  白石充典、島村達郎、浅田秀基、小林拓也、岩田想
- Organizer
  BIA Symposium 2012
- Place of Presentation
  明治記念館（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ラットP2X4受容体 Head ドメインの構造および機能解析2012
- Author(s)
  井川達弘, 阿部義人, 白石充典, 津田誠, 井上和秀, 植田正
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] NMRを用いたラットP2X4受容体headドメインの構造決定およびリガンド相互作用解析2012
- Author(s)
  井川達弘、阿部義人、白石充典、津田　誠、井上和秀、植田　正
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] ヒスタミンH1受容体の結晶構造解析2012
- Author(s)
  白石充典、島村達郎、辻本浩一、浅田秀基、小林（万木）貴美、小林拓也、岩田想
- Organizer
  平成24年度日本生化学会九州支部例会
- Place of Presentation
  福岡大学（福岡市）
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] GPCRの立体構造解析に向けた戦略:ヒスタミンH1受容体を例に2012
- Author(s)
  白石充典,島村達郎,辻本浩一,浅田秀基,小林(万木)貴美,小林拓也,岩田想
- Organizer
  日本薬学会第132 年会
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] GPCRの立体構造解明に向けた戦略：ヒスタミンH1受容体を例に2012
- Author(s)
  白石充典、島村達郎、辻本浩一、浅田秀基、小林（万木）貴美、小林拓也、岩田想
- Organizer
  日本薬学会第132年会(招待講演)
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ヒスタミンH1受容体の結晶構造解析2012
- Author(s)
  白石充典,島村達郎,辻本浩一,浅田秀基,小林(万木)貴美,小林拓也,岩田想
- Organizer
  平成24年度日本生化学会九州支部例会
- Year and Date
  2012-05-27
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ラットP2X4受容体Headドメインの構造および機能解析2012
- Author(s)
  井川達弘、阿部義人、白石充典、津田　誠、井上和秀、植田　正
- Organizer
  第12回日本蛋白質科学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] GPCR の構造研究に向けた高発現改変体作製プラットフォームの確立2011
- Author(s)
  白石充典,島村達郎,浅田秀基,小林(万木)貴美,小林拓也,岩田想
- Organizer
  平成23年度日本生化学会九州支部例会
- Year and Date
  2011-05-22
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ヒトP2X4受容体細胞外ドメインを認識するモノクロナール抗体の作製2011
- Author(s)
  望月志保、白石充典、阿部義人、津田誠、井上和秀、植田正
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会館(京都市)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] GPCRの構造解析に向けた安定化改変体の作製・評価系の確立2011
- Author(s)
  白石充典,辻本浩一,浅田秀基,島村達郎,小林(万木)貴美,小林拓也,岩田想
- Organizer
  第84回日本生化学会大会
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ヒトP2X4受容体細胞外ドメインを認識するモノクローナル抗体の作製2011
- Author(s)
  望月志保,白石充典,阿部義人,津田誠,井上和秀,植田正
- Organizer
  第84回日本生化学会大会
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] 立体構造解析を目指した膜蛋白質改変体作製プラットフォーム2011
- Author(s)
  白石充典,辻本浩一,浅田秀基,島村達郎,小林(万木)貴美,小林拓也,岩田想
- Organizer
  日本化学会東北支部平成23年度化学系学協会東北大会
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ヒト由来ヒスタミンH1受容体の結晶構造解析2011
- Author(s)
  白石充典
- Organizer
  第21回WSフォーラム(招待講演)
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ヒト由来ヒスタミンH1受容体の結晶構造解析2011
- Author(s)
  白石充典
- Organizer
  第21回WSフォーラム
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] GPCRの構造研究に向けた高発現・安定化改変体作製プラットフォーム2011
- Author(s)
  白石充典、島村達郎、辻本浩一、浅田秀基、小林（万木）貴美、小林拓也、岩田想
- Organizer
  第11回日本蛋白質科学会年会
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] 抗ラットP2X4抗体の抗原認識機構2011
- Author(s)
  井川達彦、阿部義人、東貞行、白石充典、津田誠、田中宏幸、井上和秀、植田正
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府吹田市)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] GPCRの構造研究に向けた安定化改変体の作製・評価系の確立2011
- Author(s)
  白石充典、島村達郎、辻本浩一、浅田秀基、小林（万木）貴美、小林拓也、岩田想
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] GPCRの構造研究に向けた高発現・安定化改変体作製プラットフォーム2011
- Author(s)
  白石充典,島村達郎,辻本浩一,浅田秀基,小林(万木)貴美,小林拓也,岩田想
- Organizer
  第11回日本蛋白質科学会
- Year and Date
  2011-06-08
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] GPCRの構造研究に向けた高発現改変体作製プラットフォームの確立2011
- Author(s)
  白石充典、島村達郎、浅田秀基、小林（万木）貴美、小林拓也、岩田想
- Organizer
  平成23年度日本生化学会九州支部会
- Place of Presentation
  福岡県久留米市
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] 抗ラット P2X4 抗体の抗原認識機構2011
- Author(s)
  井川達弘, 阿部義人, 東貞行, 白石充典, 津田誠, 田中宏幸, 井上和秀, 植田正
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  ホテル阪急エキスポパーク(吹田市)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] ヒト P2X4 受容体細胞外ドメインを認識するモノクローナル抗体の作製2011
- Author(s)
  望月志保, 白石充典, 阿部義人, 津田誠, 井上和秀, 植田正
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会議場(京都市)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-23390155
[Presentation] 立体構造解析を目指した膜蛋白質改変体作製プラットフォーム2011
- Author(s)
  白石充典、島村達郎、辻本浩一、浅田秀基、小林（万木）貴美、小林拓也、岩田想
- Organizer
  日本化学会東北支部　平成23年度化学系学協会東北大会(招待講演)
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-23770123
[Presentation] ヒスタミンH1受容体のリガンド認識におけるアニオン結合部位の寄与
- Author(s)
  中野祐毅、島村達郎、岩田想、植田正、白石充典
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜（横浜市）
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] ヒスタミンH1受容体のリガンド認識におけるアニオン結合部位の役割
- Author(s)
  白石充典、中野祐毅、島村達郎、岩田想、植田正
- Organizer
  第38回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Place of Presentation
  レイクサイドホテル久山（福岡県久山町）
- Year and Date
  2014-09-11 – 2014-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] P2X4細胞外ドメイン認識抗体の蛍光ゲル濾過によるスクリーニング系の確立
- Author(s)
  永井咲妃、白石充典、井川達弘、斎藤秀俊、山下智大、田中宏幸、津田誠、井上和秀、阿部義人、植田正
- Organizer
  第25回クロマトグラフィー科学会議
- Place of Presentation
  京都大学桂キャンパス（京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] P2X4受容体細胞外ドメイン認識抗体のスクリーニング系の確立
- Author(s)
  永井咲妃、白石充典、井川達弘、阿部義人、山下智大、斎藤秀俊、津田誠、井上和秀、植田正
- Organizer
  平成26年度日本生化学会九州支部会
- Place of Presentation
  九州大学馬出キャンパス（福岡市）
- Year and Date
  2014-05-17 – 2014-05-18
- Data Source
  KAKENHI-PROJECT-25709080
[Presentation] 高親和性型ヒスタミン受容体の安定化と構造解析
- Author(s)
  白石充典
- Organizer
  アステラス病態代謝研究会
- Place of Presentation
  秋葉原（東京都）
- Data Source
  KAKENHI-PROJECT-25709080

1. UEDA Tadashi (90184928)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. ABE Yoshito (60315091)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
3. ASADA Hidetsugu (20399041)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. INOUE Kazuhide (80124379)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
5. TSUDA Makoto (40373394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. 日下部宜宏 (30253595)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SHIMAMURA Tatsuro (90391979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. TAKUYA Kobayashi (20311730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. TANAKA Hiroyuki (30253470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. SAITO Hidetoshi (90444794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宗孝紀 (60294964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 浜窪隆雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 黒木喜美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shiroishi Mitsunori 白石 充典

SHIROISHI Mitsunori 白石 充典

Research Projects

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Co-Researchers

Elucidation of the molecular recognition of stereotype rheumatoid factor.Principal Investigator

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Creation of the membrane-protein-particle antigen for the effective production of a crystallization-facilitator antibodyPrincipal Investigator

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Fundamental Study on Preparations for Therapeutic Antibodies with Less Productions of Anti-Drug Antibodies

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Establishment of research foundation on "objective pain assessment" using animal models suffering from neuropathic pain

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Crystallization of Angiotensin receptor type 2 with its specific antibody

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Development of the strategy for creating stabilized GPCR variants for large-scale preparationPrincipal Investigator

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Study on the development of molecules for depressing neuropathic pain based on tertiary structure of human P2X4 receptor

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Development of Fab molecule with the stable scaffold for next generation

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Elucidating of inhibition mechanism of anti-histamines for the histamine receptor by X-ray crystallography.Principal Investigator

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Crystallization of GPCR and its specific antibody

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Elucidation of the transport mechanism of a secondary active transporter, Mhp1.

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[Journal Article] Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions2022

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[Journal Article] Structural Basis of a Conventional Recognition Mode of IGHV1-69 Rheumatoid Factors.2020

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Shiroishi Mitsunori 白石充典

SHIROISHI Mitsunori 白石充典