Tanno Masaya 丹野雅也

… Alternative Names

TANNO Masaya 丹野雅也

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Researcher Number	00398322
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 札幌医科大学, 保健医療学部, 教授 2017 – 2023: 札幌医科大学, 医学部, 准教授 2010 – 2016: 札幌医科大学, 医学部, 講師 2007 – 2010: Sapporo Medical University, 医学部, 助教 2006: 札幌医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Cardiovascular medicine / Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Circulatory organs internal medicine / Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator 細胞死 / 心不全 / 酸化ストレス / AMPデアミナーゼ / 糖尿病性心筋症 / 細胞内局在 / ヒストン脱アセチル化酵素 / diabetic cardiomyopathy / mitochondria / MAM … More / AMPD3 / ミトコンドリア近接小胞体膜 / 小胞体 / ミトコンドリア / ミトコンドリア小胞体近接領域 / AMPデミナーゼ / Sarcoplasmic Reticulum / 拡張機能障害 / GSK-3β / グリコーゲン合成酵素キナーゼ3β / グリコーゲン合成酵素キナーゼ3beta / ミトコンドリア透過性遷移孔 / 糖尿病 / SIRT1 / エピジェネティクス / 分子心臓病態学 … More Except Principal Investigator ネクロプトーシス / 細胞死 / 心不全 / 細胞内情報伝達 / オートファジー / mTOR / ミトコンドリア / 心筋細胞 / 拡張型心筋症 / ネクローシス / autophagy / necroptosis / cell death / mitochondria / signal transduction / MLKL / 細胞骨格 / 細胞内シグナル伝達 / 炎症 / レニン―アンジオテンシン系 / 造影剤腎症 / forced hydratiom / hydration / inflammation / acute kidney injury / signal tranduction / heart failure / TFEB / mTORC1 / RIP1 / 循環器・高血圧 / TNF-alpha / ラパマイシン / 分子心臓病学 / 透過性遷移孔 / 活性酸素 / 細胞内情報電達 / β-subunit / G protein coupled receptor / connexin-43 / 細胞シグナル / コネキシン Less

ネクロプトーシス実行因子MLKLを標的とした心不全治療の開発
- Principal Investigator
  
  矢野俊之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Sapporo Medical University
Role of non-classical renin-angiotensin system in contrast induced nephropathy
- Principal Investigator
  
  Moniwa Norihito
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Sapporo Medical University
Intracellular signal transduction regulating necroptosis of cardiomyocytes
- Principal Investigator
  
  Miura Tetsuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Sapporo Medical University
Mechanisms underlying regulation of AMP deaminase activity and its involvement in the pathophysiology of diabetic cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  Tanno Masaya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Sapporo Medical University
Necroptosis-tartgeted therapy for heart failure
- Principal Investigator
  
  Yano Toshiyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Sapporo Medical University
Cross-talk of cardiomyocyte necroptosis and autophagy in heart failure
- Principal Investigator
  
  Tetsuji Miura
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Sapporo Medical University
Development of novel therapeutic approach for diabetic cardiomyopathy by modification of AMP deaminase activity.Principal Investigator
- Principal Investigator
  
  Tanno Masaya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Sapporo Medical University
The role of aberrant mTOR activation in heart failure
- Principal Investigator
  
  Yano Toshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Sapporo Medical University
Novel therapeutic approach for heart failure by suppression of mitochondrial translocation of GSK-3betaPrincipal Investigator
- Principal Investigator
  
  Tanno Masaya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Sapporo Medical University
Role of mitochondrial permeability transition in necroptosis of the cardiomyocyte
- Principal Investigator
  
  Miura Tetsuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Sapporo Medical University
Novel therapeutic approach for heart failure by promoting nuclear translocation of SIRT1, a protein deacetylasePrincipal Investigator
- Principal Investigator
  
  TANNO Masaya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Sapporo Medical University
Protein kinases regulating the mitochondrial permeability transition pore
- Principal Investigator
  
  TETSUJI Miura
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Sapporo Medical University
Clarification of mechanisms to regulate the activity of protein deacetylase SIRT1 and its therapeutic application in heart failurePrincipal Investigator
- Principal Investigator
  
  TANNO Masaya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Sapporo Medical University
Role of connexin-43 in protective signaling incardiomyocyte
- Principal Investigator
  
  MIURA Tetsuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Sapporo Medical University
ヒストン脱アセチル化酵素SIRT1の細胞内局在の調節と心不全治療への応用Principal Investigator
- Principal Investigator
  
  丹野雅也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Sapporo Medical University

[Book] 今日の疾患辞典2019
- Author(s)
  丹野雅也、三浦哲嗣
- Publisher
  株式会社プレシジョン
- Data Source
  KAKENHI-PROJECT-17K09584
[Book] 医学のあゆみ2017
- Author(s)
  舘越勇輝、丹野雅也
- Total Pages
  2
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-17K09584
[Journal Article] Role of AMP deaminase in diabetic cardiomyopathy2024
- Author(s)
  Miura T, Kouzu H, Tanno M, Tatekoshi Y, Kuno A
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: - Issue: 12 Pages: 3195-3211
- DOI
  10.1007/s11010-024-04951-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07481, KAKENHI-PROJECT-21K08035
[Journal Article] Nuclear translocation of MLKL enhances necroptosis by a RIP1/RIP3-independent mechanism in H9c2 cardiomyoblasts.2023
- Author(s)
  Ino S, Yano T, Kuno A, Tanno M, Kouzu H, Sato T, Yamashita T, Ohwada W, Osanami A, Ogawa T, Toda Y, Shimizu M, Miura T.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 2 Pages: 134-143
- DOI
  10.1016/j.jphs.2022.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08035, KAKENHI-PROJECT-22K08189
[Journal Article] Downregulation of extramitochondrial <scp>BCKDH</scp> and its uncoupling from <scp>AMP</scp> deaminase in type 2 diabetic <scp>OLETF</scp> rat hearts2023
- Author(s)
  Ogawa Toshifumi、Kouzu Hidemichi、Osanami Arata、Tatekoshi Yuki、Sato Tatsuya、Kuno Atsushi、Fujita Yugo、Ino Shoya、Shimizu Masaki、Toda Yuki、Ohwada Wataru、Yano Toshiyuki、Tanno Masaya、Miki Takayuki、Miura Tetsuji
- Journal Title
  
  Physiological Reports
  
  Volume: 11 Issue: 4
- DOI
  10.14814/phy2.15608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08189, KAKENHI-PROJECT-20K08452
[Journal Article] Adenosine monophosphate deaminase in the endoplasmic reticulummitochondria interface promotes mitochondrial Ca2+ overload in type 2 diabetes rat hearts.2023
- Author(s)
  Osanami A, Sato T, Toda Y, Shimizu M, Kuno A, Kouzu H, Yano T, Ohwada W, Ogawa T, Miura T, Tanno M.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 14 Issue: 4 Pages: 560-569
- DOI
  10.1111/jdi.13982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08452, KAKENHI-PROJECT-22K08189, KAKENHI-PROJECT-21K08035, KAKENHI-PROJECT-21K08110
[Journal Article] Enhanced nuclear localization of phosphorylated MLKL predicts adverse events in patients with dilated cardiomyopathy2022
- Author(s)
  Fujita Y, Yano T, Kanamori H, Nagahara D, Muranaka A, Kouzu H, Mochizuki A, Koyama M, Nagano N, Fujito T, Nishikawa R, Kamiyama N, Tanaka M, Kuno A, Tanno M, Miura T
- Journal Title
  
  ESC Heart Failure
  
  Volume: 9 Issue: 5 Pages: 3435-3451
- DOI
  10.1002/ehf2.14059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08035, KAKENHI-PROJECT-22K08189, KAKENHI-PROJECT-22K08313
[Journal Article] 糖尿病性心筋症におけるAMPデアミナーゼの役割2021
- Author(s)
  丹野雅也, 長南新太, 小川俊史, 神津英至
- Journal Title
  
  BIO Clinica
  
  Volume: 36 Pages: 762-767
- Data Source
  KAKENHI-PROJECT-21K08110
[Journal Article] Activation of the angiotensin II receptor promotes autophagy in renal proximal tubular cells and affords protection from ischemia/reperfusion injury2021
- Author(s)
  Sugawara Hirohito、Moniwa Norihito、Kuno Atsushi、Ohwada Wataru、Osanami Arata、Shibata Satoru、Kimura Yukishige、Abe Koki、Gocho Yufu、Tanno Masaya、Miura Tetsuji
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 145 Issue: 2 Pages: 187-197
- DOI
  10.1016/j.jphs.2020.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07068, KAKENHI-PROJECT-18K08079
[Journal Article] Xanthine oxidoreductase-mediated injury is amplified by upregulated AMP deaminase in type 2 diabetic rat hearts under the condition of pressure overload2021
- Author(s)
  Igaki Yusuke、Tanno Masaya、Sato Tatsuya、Kouzu Hidemichi、Ogawa Toshifumi、Osanami Arata、Yano Toshiyuki、Kuno Atsushi、Miki Takayuki、Nakamura Takashi、Miura Tetsuji
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 154 Pages: 21-31
- DOI
  10.1016/j.yjmcc.2021.01.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08522, KAKENHI-PROJECT-20K08452, KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-21K08110
[Journal Article] 糖尿病性心筋症に対する新規治療開発 -AMPデアミナーゼおよびキサンチンオキシダーゼ阻害による拡張機能障害改善を目指して-2021
- Author(s)
  丹野雅也
- Journal Title
  
  Research Papers of The Suzuken Memorial Foundation
  
  Volume: 39 Pages: 101-107
- Data Source
  KAKENHI-PROJECT-21K08110
[Journal Article] 糖尿病性心筋症を診断する2021
- Author(s)
  丹野雅也、長瀬ちひろ、三浦哲嗣
- Journal Title
  
  Heart View
  
  Volume: 25 Pages: 2-7
- Data Source
  KAKENHI-PROJECT-21K08110
[Journal Article] Involvement of necroptosis in contrast-induced nephropathy in a rat CKD model2021
- Author(s)
  Shibata Satoru、Moniwa Norihito、Kuno Atsushi、Kimura Ayumu、Ohwada Wataru、Sugawara Hirohito、Gocho Yufu、Tanaka Marenao、Yano Toshiyuki、Furuhashi Masato、Tanno Masaya、Miki Takayuki、Miura Tetsuji
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: Online ahead of print Issue: 7 Pages: 708-717
- DOI
  10.1007/s10157-021-02048-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07068, KAKENHI-PROJECT-20K08913, KAKENHI-PROJECT-19K08544, KAKENHI-PROJECT-19K08708, KAKENHI-PROJECT-21K08035
[Journal Article] Empagliflozin attenuates acute kidney injury after myocardial infarction in diabetic rats2020
- Author(s)
  Kuno A, Kimura Y, Mizuno M, Oshima H, Sato T, Moniwa N, Tanaka M, Yano T, Tanno M, Miki T, Miura T.
- Journal Title
  
  Sci Rep
  
  Volume: 29 Issue: 1 Pages: 7238-7238
- DOI
  10.1038/s41598-020-64380-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08544, KAKENHI-PROJECT-19K08708
[Journal Article] Distinct intra-mitochondrial localizations of pro-survival kinases and regulation of their functions by DUSP5 and PHLPP-12020
- Author(s)
  Ohwada W, Tanno M, Yano T, Ong SB, Abe K, Sato T, Kuno A, Miki T, Sugawara H, Igaki Y, Miura T.
- Journal Title
  
  Biochim Biophys Acta Mol Basis Dis
  
  Volume: 1866 Issue: 10 Pages: 165851-165851
- DOI
  10.1016/j.bbadis.2020.165851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08544, KAKENHI-PROJECT-18K08079
[Journal Article] mTORC1 Inhibition Attenuates Necroptosis Through RIP1 Inhibition-Mediated TFEB Activation2019
- Author(s)
  Abe K, Yano T, Tanno M, Miki T, Kuno A, Sato T, Kouzu H, Nakata K, Ohwada W, Kimura Y, Sugawara H, Shibata S, Igaki Y, Ino S, Miura T.
- Journal Title
  
  Biochim Biophys Acta Mol Basis Dis .
  
  Volume: 1865 Issue: 12 Pages: 165552-165552
- DOI
  10.1016/j.bbadis.2019.165552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-19K08544
[Journal Article] Canagliflozin, a sodium-glucose cotransporter-2 inhibitor, normalizes renal susceptibility to type?1 cardiorenal syndrome through reduction of renal oxidative stress in diabetic rats2019
- Author(s)
  Kimura Yukishige、Kuno Atsushi、Tanno Masaya、Sato Tatsuya、Ohno Kouhei、Shibata Satoru、Nakata Kei、Sugawara Hirohito、Abe Koki、Igaki Yusuke、Yano Toshiyuki、Miki Takayuki、Miura Tetsuji
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: in Press Issue: 4 Pages: 933-946
- DOI
  10.1111/jdi.13009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16016, KAKENHI-PROJECT-19K08544
[Journal Article] Translational regulation by miR-301b upregulates AMP deaminase in diabetic hearts.2018
- Author(s)
  Tatekoshi Y, Tanno M, Kouzu H, Abe K, Miki T, Kuno A, Yano T, Ishikawa S, Ohwada W, Sato T, Niinuma T, Suzuki H, Miura T.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 119 Pages: 138-146
- DOI
  10.1016/j.yjmcc.2018.05.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09584, KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-16K09505
[Journal Article] Empagliflozin normalizes the size and number of mitochondria and prevents reduction in mitochondrial size after myocardial infarction in diabetic hearts.2018
- Author(s)
  Mizuno M, Kuno A, Yano T, Miki T, Oshima H, Sato T, Nakata K, Kimura Y, Tanno M, Miura T
- Journal Title
  
  Physiological Reports
  
  Volume: 6 Issue: 12 Pages: e13741-e13741
- DOI
  10.14814/phy2.13741
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08079, KAKENHI-PROJECT-16K09505, KAKENHI-PROJECT-17K16016
[Journal Article] Empagliflozin, an SGLT2 Inhibitor, Reduced the Mortality Rate after Acute Myocardial Infarction with Modification of Cardiac Metabolomes and Antioxidants in Diabetic Rats2018
- Author(s)
  Oshima Hiroto、Miki Takayuki、Kuno Atsushi、Mizuno Masashi、Sato Tatsuya、Tanno Masaya、Yano Toshiyuki、Nakata Kei、Kimura Yukishige、Abe Koki、Ohwada Wataru、Miura Tetsuji
- Journal Title
  
  Journal of Pharmacology and Experimental Therapeutics
  
  Volume: 368 Issue: 3 Pages: 524-534
- DOI
  10.1124/jpet.118.253666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16016, KAKENHI-PROJECT-19K08544
[Journal Article] Does p53 Inhibition Suppress Myocardial Ischemia-Reperfusion Injury?2018
- Author(s)
  Yano T, Abe K, Tanno M, Miki T, Kuno A, Miura T, Steenbergen C
- Journal Title
  
  J Cardiovasc Pharmacol Ther
  
  Volume: 印刷中 Issue: 4 Pages: 350-357
- DOI
  10.1177/1074248418763612
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505, KAKENHI-PROJECT-18K08079
[Journal Article] Suppressed autophagic response underlies augmentation of renal ischemia/reperfusion injury by type 2 diabetes2017
- Author(s)
  Muratsubaki S, Kuno A, Tanno M, Miki T, Yano T, Sugawara H, Shibata S, Abe K, Ishikawa S, Ohno K, Kimura Y, Tatekoshi Y, Nakata K, Ohwada W, Mizuno M, Miura T
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 5311-5311
- DOI
  10.1038/s41598-017-05667-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09505
[Journal Article] Effect of sodium-glucose co-transporter-2 inhibitors on impaired ventricular repolarization in people with Type 2 diabetes2017
- Author(s)
  Sato T, Miki T, Ohnishi H, Yamashita T, Takada A, Yano T, Tanno M, Tsuchida A, Miura T.
- Journal Title
  
  Diabet Med
  
  Volume: 34 Issue: 10 Pages: 1367-1371
- DOI
  10.1111/dme.13424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09505
[Journal Article] Insufficient activation of Akt upon reperfusion because of its novel modification by reduced PP2A-B55alpha contributes to enlargement of infarct size by chronic kidney disease.2017
- Author(s)
  Toshiyuki Tobisawa*, Toshiyuki Yano*, Masaya Tanno, Takayuki Miki, Atsushi Kuno, Yukishige Kimura, Satoko Ishikawa, Hidemichi Kouzu, Keitaro Nishizawa, Hideaki Yoshida, Tetsuji Miura
- Journal Title
  
  Basic Research in Cardiology
  
  Volume: 112 Issue: 3 Pages: 31-31
- DOI
  10.1007/s00395-017-0621-6
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461133, KAKENHI-PROJECT-16K09505
[Journal Article] Diabetes increases the susceptibility to acute kidney injury after myocardial infarction through augmented activation of renal Toll-like receptors in rats2017
- Author(s)
  Ohno K, Kuno A, Murase H, Muratsubaki S, Miki T, Tanno M, Yano T, Ishikawa S, Yamashita T, Miura T
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 313 Issue: 6 Pages: H1130-H1142
- DOI
  10.1152/ajpheart.00205.2017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09505
[Journal Article] Distinct impacts of sleep-disordered breathing on glycemic variability in patients with and without diabetes mellitus2017
- Author(s)
  Nakata K, Miki T, Tanno M, Ohnishi H, Yano T, Muranaka A, Sato T, Oshima H, Tatekoshi Y, Mizuno M, Abe K, Miura T
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 12 Pages: e0188689-e0188689
- DOI
  10.1371/journal.pone.0188689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09505
[Journal Article] Suppression of autophagic flux contributes to cardiomyocyte death by activation of necroptotic pathways2017
- Author(s)
  Ogasawara M, Yano T, Tanno M, Abe K, Ishikawa S, Miki T, Kuno A, Tobisawa T, Muratsubaki S, Ohno K, Tatekoshi Y, Nakata K, Ohwada W, Miura T.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 108 Pages: 203-213
- DOI
  10.1016/j.yjmcc.2017.06.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09505
[Journal Article] Chronic Treatment With an Erythropoietin Receptor Ligand Prevents Chronic Kidney Disease-Induced Enlargement of Myocardial Infarct Size.2016
- Author(s)
  Nishizawa K, Yano T, Tanno M, Miki T, Kuno A, Tobisawa T, Ogasawara M, Muratsubaki S, Ohno K, Ishikawa S, Miura T.
- Journal Title
  
  Hypertension
  
  Volume: 68 Issue: 3 Pages: 697-706
- DOI
  10.1161/hypertensionaha.116.07480
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461133, KAKENHI-PROJECT-16K09505
[Journal Article] Clinical impact of myocardial mTORC1 activation in nonischemic dilated cardiomyopathy.2016
- Author(s)
  Yano T, Shimoshige S, Miki T, Tanno M, Mochizuki A, Fujito T, Yuda S, Muranaka A, Ogasawara M, Hashimoto A, Tsuchihashi K, Miura T
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 91 Pages: 6-9
- DOI
  10.1016/j.yjmcc.2015.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461133
[Journal Article] Inhibition of DPP-4 reduces acute mortality after myocardial infarction with restoration of autophagic response in type 2 diabetic rats.2015
- Author(s)
  Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Ishikawa S, Tobisawa T, Ogasawara M, Nishizawa K, Miura T.
- Journal Title
  
  Cardiovasc Diabetol
  
  Volume: 14 Issue: 1 Pages: 103-118
- DOI
  10.1186/s12933-015-0264-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461133
[Journal Article] Excessive degradation of adenine nucleotides by up-regulated AMP deaminase underlies afterload-induced diastolic dysfunction in the type 2 diabetic heart2015
- Author(s)
  Hidemichi Kouzu, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Toshiyuki Yano, Takahito Itoh, Tatsuya Sato, Daisuke Sunaga, Hiromichi Murase, Toshiyuki Tobisawa, Makoto Ogasawara, Satoko Ishikawa, Tetsuji Miura
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 80 Pages: 136-145
- DOI
  10.1016/j.yjmcc.2015.01.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860611, KAKENHI-PROJECT-26461132, KAKENHI-PROJECT-26461133
[Journal Article] Translocation of glycogen synthase kinase-3β (GSK-3β), a trigger of permeability transition, is kinase activity-dependent and mediated by interaction with voltage-dependent anion channel 2 (VDAC2).2014
- Author(s)
  Tanno M, Kuno A, Ishikawa S, Miki T, Kouzu H, Yano T, Murase H, Tobisawa T, Ogasawara M, Horio Y, Miura T.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 42 Pages: 29285-29296
- DOI
  10.1074/jbc.m114.563924
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461132, KAKENHI-PROJECT-26461133
[Journal Article] Type 2 diabetes induces subendocardium-predominant reduction in transient outward K+ current with downregulation of Kv4.2 and KChIP2.2014
- Author(s)
  Sato T, Kobayashi T, Kuno A, Miki T, Tanno M, Kouzu H, Itoh T, Ishikawa S, Kojima T, Miura T, Tohse N.
- Journal Title
  
  American Journal of Physiology Heart and Circulatory Physiology
  
  Volume: 306 Issue: 7 Pages: H1054-H1065
- DOI
  10.1152/ajpheart.00414.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591086
[Journal Article] Accelerated recovery of mitochondrial membrane potential by GSK-3β inactivation affords cardiomyocytes protection from oxidant-induced necrosis.2014
- Author(s)
  Sunaga D, Tanno M, Kuno A, Ishikawa S, Ogasawara M, Yano T, Miki T, Miura T
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 11 Pages: e112529-e112529
- DOI
  10.1371/journal.pone.0112529
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461133
[Journal Article] Resveratrol improves cardiomyopathy in dystrophin-deficient mice through SIRT1 Protein-mediated modulation of p300 Protein.2013
- Author(s)
  Kuno A et al.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 8 Pages: 5963-5972
- DOI
  10.1074/jbc.m112.392050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590245, KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] Reversal of metabolic shift in post-infarct remodelled hearts: possible novel therapeutic approach.2013
- Author(s)
  Tanno M, Kuno A.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 97 Issue: 2 Pages: 195-196
- DOI
  10.1093/cvr/cvs364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085
[Journal Article] Histopathology of the pancreas in fulminant type 1 diabetes after 23-year follow-up : a case report2012
- Author(s)
  Sato T, Miki T, Murakami N, Hirohashi Y, Kouzu H, Furuhashi M, Tanno M, Yuda T, Saitoh S, Hasegawa T, Miura T
- Journal Title
  
  Pathology International
  
  Volume: 62 Issue: 12 Pages: 827-29
- DOI
  10.1111/pin.12017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591106
[Journal Article] 高齢者の心不全の病態、臨床的特徴と診断・治療上の注意点2012
- Author(s)
  丹野雅也、三浦哲嗣
- Journal Title
  
  月刊循環器 Circulation
  
  Volume: 2 Pages: 38-50
- Data Source
  KAKENHI-PROJECT-23591085
[Journal Article] Emerging beneficial roles of sirtuins in heart failure.2012
- Author(s)
  Tanno M et al.
- Journal Title
  
  Basic Res Cardiol.
  
  Volume: 107 Issue: 4 Pages: 273-273
- DOI
  10.1007/s00395-012-0273-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590245, KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] Role of connexin-43 in protective PI3K-Akt-GSK-3βsignaling in cardiomyocytes2012
- Author(s)
  Ishikawa S, Kuno A, Tanno M, Miki T, Kouzu H, Itoh T, Sato T, Sunaga D, Murase H, Miura T
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 302 Issue: 12 Pages: H2536-H2544
- DOI
  10.1152/ajpheart.00940.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] The mPTP and its regulatory proteins : final common targets of signalling pathways for protection against necrosis2012
- Author(s)
  Miura T, Tanno M
- Journal Title
  
  Cardiovasc Res
  
  Volume: 94 Issue: 2 Pages: 181-9
- DOI
  10.1093/cvr/cvr302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] Role of ER Stress in Ventricular Contractile Dysfunction in Type 2 Diabetes2012
- Author(s)
  Takada A, Miki T, Kuno A, Kouzu H, Sunaga D, Itoh T, Tanno M, Yano T, Sato T, Ishikawa S, Miura T
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 6 Pages: e39893-e39893
- DOI
  10.1371/journal.pone.0039893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] Cytoprotective regulation of the mitochondrial permeability transition pore is impaired in type 2 diabetic Goto-Kakizaki rat hearts2012
- Author(s)
  Itoh T, Kouzu H, Miki T, Tanno M, Kuno A, Sato T, Sunaga D, Murase H, Miura T
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 53 Issue: 6 Pages: 870-9
- DOI
  10.1016/j.yjmcc.2012.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] Resveratrol ameliorates muscular pathology in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy2011
- Author(s)
  Hori SY, et al
- Journal Title
  
  J.Pharmacol.Exp.Ther.
  
  Volume: 338 Issue: 3 Pages: 784-794
- DOI
  10.1124/jpet.111.183210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590245, KAKENHI-PROJECT-23591085
[Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection2011
- Author(s)
  Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K and Miura T
- Journal Title
  
  Hypertension
  
  Volume: 57 Issue: 1 Pages: 110-5
- DOI
  10.1161/hypertensionaha.110.158469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591085, KAKENHI-PROJECT-23591086
[Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection.2011
- Author(s)
  Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K, Miura T.
- Journal Title
  
  Hypertension
  
  Volume: 57 Pages: 110-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591086
[Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection.2011
- Author(s)
  Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K, Miura T.
- Journal Title
  
  Hypertension 57
  
  Pages: 110-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Mitochondrial kinase signalling pathways in myocardial protection fromischaemia/reperfusion-induced necrosis2010
- Author(s)
  Miura T, Tanno M, Sato T.
- Journal Title
  
  Cardiovasc Res 88
  
  Pages: 7-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Erythropoietin (EPO) affords more potent cardioprotection by activation of distinct signaling to mitochondrial kinases compared with carbamylated EPO.2010
- Author(s)
  Sato T, Tanno M. Miki T, Yano T, Sato T, Shimamoto K, Miura T.
- Journal Title
  
  Cardiovasc Drugs Ther 24
  
  Pages: 401-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Mitochondria and GSK-3beta in cardioprotection against ischemia/reperfusion injury.2010
- Author(s)
  Miura T, Tanno M.
- Journal Title
  
  Cardiovasc Drugs Ther 24
  
  Pages: 255-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Angiotensin II type 1 receptor-mediated upregulation of calcineurin activity underlies impairment of cardioprotective signaling in diabetic hearts.2010
- Author(s)
  Hotta H, Miura T. Miki T, Togashi N, Maeda T. Kim SJ, Tanno M Yano T, Kuno A, Itoh T, Satoh T, Terashima Y, Ishikawa S, Shimamoto K.
- Journal Title
  
  Circ Res 106
  
  Pages: 129-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure2010
- Author(s)
  Tanno M, Kuno A, Yano T, Miura T, Hisahara S, Ishikawa S, Shimamoto K, Horio Y.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 8375-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection.2010
- Author(s)
  Yano T, Miki T, Tanno M, Kuno A, Itoh T, Takada A, Sato T, Kouzu H, Shimamoto K Miura T.
- Journal Title
  
  Hypertension 57
  
  Pages: 110-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Induction of manganese superoxide dismutase by nuclear translocation and activation of SIRT1 promotes cell survival in chronic heart failure2010
- Author(s)
  Tanno M, et al.
- Journal Title
  
  J Biol Chem 285
  
  Pages: 8375-8382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Roles of phospho-GSK-3β in myocardial protection afforded by activation of the mitochondrial K ATP channel.2010
- Author(s)
  Terashima Y, Sato T, Yano T, Maas O, Itoh T, Miki T, Tanno M, Kuno A, Shimamoto K, Miura T.
- Journal Title
  
  J Mol Cell Cardiol 49
  
  Pages: 762-770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Protein deacetylase SIRT1 in the cytoplasm promotes nerve growth factor-induced neurite outgrowth in PC12 cells2010
- Author(s)
  Sugino T, Maruyama M, Tanno M, Kuno A, Houkin K, Horio Y.
- Journal Title
  
  FEBS Lett 584
  
  Pages: 2821-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Endoplasmic reticulum stress in diabetic hearts abolishes erythropoietin-induced myocardial protection by impairment of phospho-glycogen synthase kinase-3β-mediated suppression of mitochondrial permeability transition.2009
- Author(s)
  Miki T Miura T, Hotta H, Tanno M, Yano T, Sato T, Terashima Y, Takada A, Ishikawa S, Shimamoto K.
- Journal Title
  
  Diabetes 58
  
  Pages: 2863-2872
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Endoplasmic reticulum stress in diabetic hearts abolishes erythropoietin-induced myocardial protection by impairment of phospho-glycogen synthase kinase 3beta-mediated suppression of mitochondrial permeability transition2009
- Author(s)
  Miki T, Miura T, Hotta H, Tanno M, Yano T, Sato T, Ishikawa S, Shimamoto K.
- Journal Title
  
  Diabetes 58
  
  Pages: 2863-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Roles of Cx43-associated protein kinases in suppression of gap junction-mediated chemical coupling by ischemic preconditioning.2009
- Author(s)
  Naitoh K, Yano T, Miura T, Itoh T, Miki T Tanno M Sato T, Hotta H, Terashima Y, Shimamoto K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Limitation of infarct size by erythropoietin is associated with translocation of Akt to the mitochondria after reperfusion.2008
- Author(s)
  Kobayashi H, Miura T. Ishida H, Miki T. Tanno M Yano T, Sato T, Hotta H, Shimamoto K.
- Journal Title
  
  Clin Exp Pharmacol Physiol 35
  
  Pages: 812-819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation2008
- Author(s)
  Hisahara S, Chiba S, Matsumoto H, Tanno M, Yagi H, Shimohama S, Horio Y.
- Journal Title
  
  Proc Natl Acad Sci U S A 105
  
  Pages: 15599-15604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590869
[Journal Article] Adenine nucleotide translocator, a mitochondrial carrier protein, and fate of cardiomyocytes after ischaemia/reperfusion.2008
- Author(s)
  Tanno M, Miura T.
- Journal Title
  
  Cardiovasc Res 80
  
  Pages: 1-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Ser9 phosphorylation of mitochondrial GSK-3β is a primary mechanism of cardiomyocyte protection by erythropoietin against oxidant-induced apoptosis.2008
- Author(s)
  Ohori K, Miura T, Tanno M, Miki T, Sato T, Ishikawa S, Horio Y, Shimamoto K.
- Journal Title
  
  Am J Physiol Heart Circ Physiol 295
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590870
[Journal Article] Nucleocytoplasmic Shuttling of the NAD^+-dependent Histone Deacetylase SIRT12007
- Author(s)
  Masaya Tanno
- Journal Title
  
  The journal of biological chemistry 282・9
  
  Pages: 6823-6832
- Data Source
  KAKENHI-PROJECT-18790505
[Journal Article] Nucleocytoplasmic Shuttling of the NAD-dependent Histone deacetylase SIRT12007
- Author(s)
  Masaya Tanno
- Journal Title
  
  The Journal of Biological Chemistry 282
  
  Pages: 6823-6832
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790505
[Presentation] Enhanced nuclear localization of MLKL promotes necroptosis of cardiomyocytes and predicts prognosis in dilated cardiomyopathy.2023
- Author(s)
  YanoT, Fujita Y, Ino S, Ohwada W, Kouzu H, Kuno A, Tanno M, Furuhashi M, Miura T.
- Organizer
  第87回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08035
[Presentation] Enhanced nuclear localization of MLKL promotes necroptosis of cardiomyocytes and predicts prognosis in dilated cardiomyopathy2022
- Author(s)
  Toshiyuki Yano, Yugo Fujita, Shoya Ino, Wataru Ohwada, Hidemichi Kouzu, Atsushi Kuno, Masaya Tanno, Masato Furuhashi, Tetsuji Miura
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-22K08189
[Presentation] Upregulated AMP Deaminase in Mitochondria-associated ER Membranes in Diabetic Hearts Lowers the Threshold for Mitochondrial Permeability Transition.2022
- Author(s)
  Osanami A, Tanno M, Kuno A, Kouzu H, Yano T, Ogawa T, Sato T, Toda Y, Miura T.
- Organizer
  第86回日本循環器学会年次学術集会
- Data Source
  KAKENHI-PROJECT-21K08110
[Presentation] Upregulated AMP deaminase in mitochondria-associated ER membranes in diabetic hearts lowers the threshold for mitochondrial permeability transition.2022
- Author(s)
  Osanami A, Tanno M, Kuno A, Kouzu H, Yano T, Ogawa T, Sato T and Miura T
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-21K08110
[Presentation] Upregulated AMP Deaminase in Mitochondria-associated ER Membranes and Cytosol Distinctively Contributes to Pressure Overload-induced Cardiac Dysfunction in Diabetic Hearts.2021
- Author(s)
  Tanno M, Osanami A, Kouzu H, Ogawa T, Kuno A, Miura T.
- Organizer
  日本循環器学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08110
[Presentation] AMP deaminase in mitochondria-associated ER membranes contributes to reduction of the threshold for mitochondrial permeability transition in type 2 diabetic hearts.2021
- Author(s)
  Osanami A, Tanno M, Kuno A, Kouzu H, Yano T, Ogawa T, Sato T and Miura T
- Organizer
  日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-21K08110
[Presentation] AMP deaminase in mitochondria-associated ER membranes contributes to reduction of the threshold for mitochondrial permeability transition in type 2 diabetic hearts.2021
- Author(s)
  Osanami A, Tanno M, Kuno A, Kouzu H, Yano T, Ogawa T, Sato T and Miura T.
- Organizer
  American Heart Association scientific session
- Data Source
  KAKENHI-PROJECT-21K08110
[Presentation] 糖尿病性心筋症の病態・治療の現状とこれから2021
- Author(s)
  丹野雅也
- Organizer
  日本糖尿病学会　糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-21K08110
[Presentation] Novel regulation of cardiac branched-chain amino acid metabolism through AMP deaminase: A possible therapeutic target for diabetic cardiomyopathy.2020
- Author(s)
  Ogawa T, Kouzu H, Tatekoshi Y, Osanami A, Oshima H, Mizuno M, Kuno A, Igaki Y, Sugawara H, Fujita Y, Sato T, Yano T, Tanno M, Miki T, Miura T.
- Organizer
  European Society of Cardiology Congress 2020
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] Accumulation of free iron, but not protein-bound iron, in mitochondria may contribute to development of doxorubicin-induced cardiomyopathy.2020
- Author(s)
  Sato T, Kikuchi T, Yano T, Miki T, Tanno M, Kuno A, Kouzu H, Miura T.
- Organizer
  日本循環器学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Inhibition of xanthine oxidase ameliorates functional and metabolic impairment in type 2 diabetic hearts under pressure overload.2020
- Author(s)
  Igaki Y, Osanami A, Tanno M, Sato T, Ogawa T, Yano T, Kouzu H, Miura T
- Organizer
  European Society of Cardiology Congress 2020
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] Reduced level of caspase-8, an endogenous inhibitor of necroptosis, is associated with left ventricular enlargement in dilated cardiomyopathy.2019
- Author(s)
  Fujita Y, Yano T, Nagano N, Kamiyama N, Fujito T, Mochizuki A, Koyama M, Kouzu H, Muranaka A, Nagahara D, Tanno M, Miki T, Miura T.
- Organizer
  第83 回日本循環器学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Inhibitory phosphorylation of RIP1 at Ser320 induces nuclear translocation of TFEB, leading to suppression of necroptosis in cadiomyocytes.2019
- Author(s)
  Abe K, Yano T, Sato T, Kouzu H, Kuno A, Tanno M, Miki T, Miura T.
- Organizer
  ESC congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Pressure overload-induced functional and metabolic impairments in type 2 diabetic hearts are ameliorated by inhibition of xanthine oxidase2019
- Author(s)
  Igaki Y, Tanno M, Kouzu H, Sato T, Tatekoshi Y, Yano T, Kuno A, Miki T, Miura T.
- Organizer
  ESC asia with APCS and AFC
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] mTORC1 活性阻害はRIP1 の抑制的リン酸化により心筋細胞のネクロプトーシスを抑制する2019
- Author(s)
  矢野俊之, 安部功記, 佐藤達也, 神津英至, 久野篤史, 丹野雅也, 三木隆幸, 三浦哲嗣
- Organizer
  第40 回日本循環制御医学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Functional and metabolic impairments in type 2 diabetic hearts under pressure overload are improved by inhibition of xanthine oxidase.2019
- Author(s)
  Igaki Y, Tanno M, Sato T, Yano T, Kuno A, Miura T.
- Organizer
  日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] Activation of necroptotic pasthway by downregulated caspase-8 expression is associated with progression of left ventricular remodeling in nonischemic dilated cardiomyopathy.2019
- Author(s)
  Fujita Y, Yano T, Abe K, Nagano N, Kamiyama N, Fujito T, Mochizuki A, Koyama M, Kouzu H, Muranaka A, Nagahara D, Tanno M, Miki T, Miura T.
- Organizer
  ESC congress 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Impact of activation of necroptotic signaling on mitochondrial dynamics in cardiomyocytes.2019
- Author(s)
  Yano T, Ong S, Sato T, Kouzu H, Kuno A, Tanno M, Miki T, Miura T.
- Organizer
  CVMW2019 心血管代謝週間
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Distinct expressions of caspase-8 and phospho-MLKL, necroptosis regulatory proteins, in nonischemic dilated cardiomyopathy.2019
- Author(s)
  Fujita Y, Yano T, Abe K, Nagano N, Nishikawa R, Kamiyama N, Fujito T, Mochizuki A, Koyama M, Kouzu H, Muranaka A, Nagahara D, Tanno M, Miki T, Miura T.
- Organizer
  第23 回日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08544
[Presentation] Activation of necroptotic pasthway by downregulated caspase-8 expression is associated with progression of left ventricular remodeling in nonischemic dilated cardiomyopathy.2019
- Author(s)
  Fujita Y, Yano T, Abe K, Nagano N, Kamiyama N, Fujito T, Mochizuki A, Koyama M, Kouzu H, Muranaka A, Nagahara D, Tanno M, Miki T, Miura T
- Organizer
  ESC congress 2019. Paris, France.
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] Novel microRNA-mediated regulation of AMP deaminase, a key player in diabetic cardiomyopathy.2019
- Author(s)
  Tanno M.
- Organizer
  日本循環器学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] Synergetic effect of amino acid and ketone metabolism underlies empagliflozin-mediated cardioprotection in the type 2 diabetic heart.2019
- Author(s)
  Kouzu H, Oshima H, Miki T, Kuno A, Sato T, Yano T, Tanno M, Miura T.
- Organizer
  ESC asia with APCS and AFC
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] 糖尿病性心筋症における拡張機能障害は、キサンチンオキシダーゼ阻害により抑制される2019
- Author(s)
  井垣勇祐, 丹野雅也, 神津英至, 佐藤達也,三浦哲嗣
- Organizer
  日本心筋症研究会
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] Novel microRNA-mediated regulation of AMP deaminase, a key player in diabetic cardiomyopathy2019
- Author(s)
  丹野雅也
- Organizer
  日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] mTORC1 suppresses cardiomyocyte necroptosis through autophagy and RIP1 inhibition2018
- Author(s)
  Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Miura T.
- Organizer
  日本循環器学会基礎医学フォーラム
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] mTORC1 suppresses cardiomyocyte necroptosis through autophagy and RIP1 inhibition2018
- Author(s)
  Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Miura T
- Organizer
  第 2 回日本循環器学会基礎研究フォーラム平成 30 年 9 月 22-23 日奈良
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] mTORC1 inhibition suppresses necroptosis through restroration of autophagic flux by inhibitory phosphorylation of RIP1 in cardiomyocytes.2018
- Author(s)
  Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Mizuno M, Miura T.
- Organizer
  European Society of Cardiology Congress 2018, Munich, Germany. August 25-29, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Inhibition of mTORC1 supresses necroptosis of cardiomyocytes in a p70S6K-independent mechanism by suppression of p62-RIP1 interaction.2018
- Author(s)
  Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Miura T.
- Organizer
  第82回日本循環器学会学術集会平成30年3月23-25日大阪
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Inhibition of mTORC1 supresses necroptosis of cardiomyocytes in a p70S6K-independent mechanism by suppression of p62-RIP1 interaction.2018
- Author(s)
  Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Miura T.
- Organizer
  日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] Crosstalk between Aberrant mTORC1 Activation and Necroptotic Pathway: a Novel Therapeutic Target in Ischemic Heart Disease.2018
- Author(s)
  Yano T, Abe K, Ogasawara M, Kuno A, Tanno M, Miki T, Miura T.
- Organizer
  第82回日本循環器学会学術集会平成30年3月23-25日大阪
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] mTORC1 inhibition restores autophagic flux by inhibitory phosphorylation of RIP1, leading to suppression of necroptosis in cardiomyocytes.2018
- Author(s)
  Abe K, Yano T, Ogasawara M, Miki T, Tanno M, Kuno A, Miura T.
- Organizer
  The 5th International Symposium New Frontiers Cardiovascular Research, Sapporo, Japan. June 22-24, 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] mTORC1 inhibition suppresses necroptosis through restroration of autophagic flux by inhibitory phosphorylation of RIP1 in cardiomyocytes.2018
- Author(s)
  Abe K, Yano T, Miki T, Tanno M, Kuno A, Sato T, Mizuno M, Miura T.
- Organizer
  European Society of Cardiology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] Crosstalk between Aberrant mTORC1 Activation and Necroptotic Pathway: a Novel Therapeutic Target in Ischemic Heart Disease2018
- Author(s)
  Yano T, Abe K, Ogasawara M, Kuno A, Tanno M, Miki T, Miura T.
- Organizer
  日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08079
[Presentation] mTOR inhibition restores dysregulation of p62 interactosomes and attenuates RIP1/RIP3-mediated necroptosis in cardiomyocytes2017
- Author(s)
  Kouki Abe, Makoto Ogasawara, Toshiyuki Yano, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Satoko Ishikawa, Tetsuji Miura
- Organizer
  第81回日本循環器学会年次学術集会
- Place of Presentation
  石川県立音楽堂他（石川県金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Dysregulation of miR-301b Contributes to Diabetic Cardiomyopathy via Upregulation of AMP Deaminase in the Vicinity of the Sarcoplasmic Reticulum2017
- Author(s)
  Tatekoshi Y, Tanno M, Miki T, Kuno A, Yano T, Ohwada W, Abe K, Igaki Y, Fujita Y, Miura T
- Organizer
  American Heart Association 2017. Anaheim, CA, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] A novel role of tristetraprolin in regulation of reactive oxygen species production by optimizing iron containing proteins.2017
- Author(s)
  Sato T, Tanno M, Yano T, Miki T, Ardehali H, Miura T
- Organizer
  Cardiovascular and Metabolic Week 2017 (CVMW2017) 第 34 回国際心臓研究学会日本部会
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Dysregulation of miR-301b contributes to diabetic cardiomyopathy via upregulation of AMP deaminasein the vicinity of the sarcoplasmic reticulum2017
- Author(s)
  Tatekoshi Y, Tanno M, Miki T, Kuno A, Yano T, Ohwada W, Abe K, Igaki Y, Fujita Y and Miura T
- Organizer
  American Heart Association 2017 . Anaheim, CA, U.S.A
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] Inhibition of mTORC1 but not p53 suppresses RIP1-dependent necroptosis through activation of autophagy in cardiomyocytes2017
- Author(s)
  Yano T, Abe K, Ogasawara M, Kuno A, Tanno M, Miki T, Miura T.
- Organizer
  Cardiovascular and Metabolic Week 2017 (CVMW2017) 第 34 回国際心臓研究学会日本部会
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Blunted response of Akt-Ser473 upon reperfusion by reduced PP2A-B55α contributes to enlargement of infarct size by chronic renal failure2017
- Author(s)
  Yukishige Kimura, Toshiyuki Tobisawa, Toshiyuki Yano, Takayuki Miki, Masaya Tanno, Atsushi Kuno, Tetsuji Miura
- Organizer
  第81回日本循環器学会年次学術集会
- Place of Presentation
  石川県立音楽堂他（石川県金沢市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Upregulation of AMP deaminase in the vicinity of the SR via translational regulation by miR - 301b contributes to diabetic cardiomyopathy2017
- Author(s)
  Tatekoshi Y, Tanno M, Miki T, Kuno A, Yano T, Ohwada W, Abe K, Igaki Y, Fujita Y, Miura T.
- Organizer
  日本心不全学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] Upregulation of Toll-like Receptors That Underlies Diabetes-induced Exacerbation of Cardiorenal Syndrome is Attenuated by Canagliflozin, an SGLT2 Inhibitor.2017
- Author(s)
  Kimura Y, Ohno K, Kuno A, Mizuno M, Ohshima H, Yano T, Tanno M, Miki T, Miura T.
- Organizer
  American Heart Association 2017. Anaheim, CA, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Empagliflozin, an SGLT2 inhibitor, reduces mortality after myocardial infarction in diabetic rats by increasing ATP production and reducing oxidative stress.2017
- Author(s)
  Oshima H, Mizuno M, Miki T, Kuno A, Sato T, Kimura Y, Abe K, Yano T, Tanno M, Miura T.
- Organizer
  Cardiovascular and Metabolic Week 2017 (CVMW2017) 第 34 回国際心臓研究学会日本部会
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Upregulation of AMP deaminase in the vicinity of sarcoplasmic reticulum through miRNA mediated translational regulation : a novel mechanism of diabetic cardiomyopathy2017
- Author(s)
  Tatekoshi Y, Tanno M, Miki T, Kuno A, Yano T, Ono K, Ohwada W, Mizuno M, Nakata K, Abe K and Miura T
- Organizer
  日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09584
[Presentation] Mitochondrial translocation of DUSP5 and PHLPP-1, protein phosphatases targeting ERK and Akt, cancels cell-protective signals of mitochondrial protective kinases under oxidative stress2017
- Author(s)
  Ohwada W, Tanno M, Kuno A, Yano T, Miki T, Tatekoshi Y, Abe K, Sato T, Ishikawa S, Miura T.
- Organizer
  European Society of Cardiology Congress 2017. Barcelona, Spain.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Molecular crosstalk between necroptosis and autophagy signaling pathways: roles of p62 and p53.2017
- Author(s)
  Abe K, Yano T, Ogasawara M, Miki T, Tanno M, Kuno A, Miura T.
- Organizer
  American Heart Association 2017. Anaheim, CA, U.S.A.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Effects of empagliflozin, an SGLT2 inhibitor, on mitochondrial dynamics in the non-infarcted region of the heart after myocardial infarction in diabetic rats.2017
- Author(s)
  Mizuno M, Ohshima H, Miki T, Kuno A, Yano T, Sato T, Tanno M, Kimura Y, Miura T.
- Organizer
  Cardiovascular and Metabolic Week 2017 (CVMW2017) 第 34 回国際心臓研究学会日本部会
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Increased activity of AMP deaminase by decreased interaction with PGM1 and depletion of F1,6P: a novel mechanism of diabetic cardiomyopathy2016
- Author(s)
  Y. Tatekoshi, H. Kouzu, M. Tanno, A. Kuno, S. Ishikawa, T. Yano, T. Miki , M. Ogasawara, T. Tobisawa, K. Ono, S. Muratsubaki, K. Nishizawa, T. Miura
- Organizer
  22nd Congress of International Society for Heart Research
- Place of Presentation
  Buenos Aires, Argentina
- Year and Date
  2016-04-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Sequestration of p62 by RIP1 promotes necroptosis through suppression of autophagic flux in cardiomyocytes; a novel cross-talk between autophagy and necroptosis2016
- Author(s)
  Yano T, Ogasawara M, Miki T, Tanno M, Kuno A, Ohno K, Nishizawa K, Owada W, Mizuno M, Suwawara H, Tatekoshi Y, Nakata K, Ishikawa S, Miura T
- Organizer
  European Society of Cardiology Congress 2016
- Place of Presentation
  Rome, Italy
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461133
[Presentation] Excessive ROS production in mitochondria switches off protective mitochondrial kinase signaling.2016
- Author(s)
  Tanno M, Ohwada W, Yano T, Miki T, Kuno A, Ishikawa S, Tatekoshi Y, Nishizawa K, Mizuno M, Miura T.
- Organizer
  4th Congress of Frontiers in Cardiovascular Biology
- Place of Presentation
  Florence, Italy
- Year and Date
  2016-07-08
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Excessive ROS production in mitochondria switches off protective mitochondrial kinase signaling2016
- Author(s)
  Owada W, Tanno M, Yano T, Miki T, Kuno A, Ishikawa S, Tatekoshi Y, Nishizawa K, Mizuno M, Miura T.
- Organizer
  4th Congress of Frontiers in CardioVascular Biology, European Society of Cardiology
- Place of Presentation
  Florence, bItaly
- Year and Date
  2016-07-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] ROS-induced mitochondrial translocation of phosphatases cancelscell-protective signals activated by phosphorylation of mitochondrial protective kinases2016
- Author(s)
  Ohwada W, Tanno M, Yano T, Kuno A, Miki T, Ishikawa S, Tatekoshi Y, Abe K, Ohno K, Mizuno M, Nakata K, Miura T.
- Organizer
  89th Scientific Session of American Heart Association
- Place of Presentation
  New Orleans, U.S.A.
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Upregulation of AMP deaminase activity in diabetic hearts by decreased interaction with phosphoglucomutase-1 and depletion of fructose 1,6-diphosphate: a novel mechanism for diabetic cardiomyopathy2016
- Author(s)
  Tatekoshi Y, Tanno M, Kouzu H, Miki T, Kuno A, Ishikawa S, Yano T, Ohwada W, Ohno K, Mizuno M, Nishizawa K, Nakata K, Miura T.
- Organizer
  European Society of Cardiology
- Place of Presentation
  Roma, Italy
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Restoration of the intra-mitochondrial interplay between protective signals and malate-aspartate shuttle by continuous erythropoietin receptor activation prevents CKD-induced infarct size enlargement2016
- Author(s)
  Nishizawa K, Yano T, Miki T, Tanno M, Kuno A, Tobisawa T, Ogasawara M, Muratsubaki S, ohno K, Mizuno M, Ohwada W, Ishikawa S, Miura T.
- Organizer
  European Society of Cardiology
- Place of Presentation
  Roma, Italy
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Depletion of fructose 1,6-diphosphate but not post-translational modification plays a major role in activation of AMP deaminase in diabetic hearts: a novel mechanism for diabetic cardiomyopathy.2016
- Author(s)
  Y. Tatekoshi, M. Tanno, A. Kuno, S. Ishikawa, T. Yano, T. Miki, M. Ogasawara, T. Tobisawa, K. Ohno, S. Muratsubaki, K. Nishizawa, T. Miura
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Sequestration of p62 by RIP1 promotes necroptosis through suppression of autophagic flux in cardiomyocytes; a novel cross-talk between autophagy and necroptosis2016
- Author(s)
  Yano T, Ogasawara M, Miki T, Tanno M, Kuno A, ohno K, Nishizawa K, Owada W, Mizuno M, Suwawara H, Tatekoshi Y, Nakata K, Ishikawa S, Miura T.
- Organizer
  European Society of Cardiology
- Place of Presentation
  Roma, Italy
- Year and Date
  2016-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09505
[Presentation] Intramolecular inhibition of Ser473 phosphorylation by up-regulated Thr308 phosphorylation in Akt cotributes to enlargement of infarct size by chronic renal failure.2015
- Author(s)
  T. Tobisawa, T. Yano, T. Miki, M. Tanno, A. Kuno, H. Kouzu, M. Ogasawara, S. Muratsubaki, K. Ohno, K. Nishizawa, M. Mizuno, W. Owada, S. Ishikawa, T. Miura.
- Organizer
  88th Scientific Session of American Heart Association:
- Place of Presentation
  Orlando, U.S.A.
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Continuous erythropoietin receptor activation reverses increased myocardial susceptibility to ischemia/reperfusion injury in chronic renal failure.2015
- Author(s)
  K. Nishizawa, T. Yano, T. Miki, M. Tanno, A. Kuno, H. Kouzu, T. Tobisawa, M. Mizuno, H. Sugawara, T. Miura.
- Organizer
  37th Congress of the European Society of Cardiology
- Place of Presentation
  London, UK
- Year and Date
  2015-08-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Suppression of Autophagic Flux by Sequestration of p62 Promotes RIP1-mediated Necroptosis in Cardiomyocytes2015
- Author(s)
  Makoto Ogasawara; Toshiyuki Yano; Takayuki Miki; Masaya Tanno; Atsushi Kuno; Hidemichi Kouzu; Toshiyuki Tobisawa; Shingo Muratsubaki; Kohei Ohno; Keitaro Nishizawa; Satoko Ishikawa; Tetsuji Miura
- Organizer
  Scientific Sessions of the American Heart Association 2015
- Place of Presentation
  Orlando, USA
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461133
[Presentation] Iroquois Homeodomain 5 (Irx5) is Upregulated via Increased ER Stress in Type 2 Diabetic Hearts2013
- Author(s)
  Sato T, Kuno A, Kobayashi T, Miki T, Tanno M, Ishikawa S, Miura T, Tohse N
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-15
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Type 2 diabetes induces ventricular electrical remodeling with a transmural gradient2013
- Author(s)
  Tobisawa T, Sato T, Yuda S, Miki T, Tanno M, Kuno A, Kobayashi T, Akasaka H, Tohse N, Miura T
- Organizer
  European Society of Cardiology Congress 2013
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Promotion of Re-closure of the mPTP Underlies Cardiomyocyte Protection by Activation of the Mitochondrial KATP Channel against ROS-induced Necrosis2013
- Author(s)
  Sunaga D, Kuno A, Ishikawa S, Miki T, Tanno M, Kouzu H, Itoh T, Sato T, Murase H, Miura T
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-17
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Interaction of cyclophilin D with inorganic phosphate carrier during ischemia determines threshold for mPTP opening and reperfusion-induced cell necrosis2013
- Author(s)
  Ito T, Kouzu H, Miki T, Tanno M, Kuno A, Sato T, Sunaga D, Murase H, Ishikawa S, Miura T
- Organizer
  The 77^<th> Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Mechanisms underlying mitochondrial translocation of GSK-3beta, a crucial induces of mitochondrial permeability transition : GSK-3beta activity, interaction with VDAC2 and a mitochondrial targeting sequence2013
- Author(s)
  Tanno M, Kuno A, Ishikawa S, Ogasawara M, Tobisawa T, Murase H, Sato T, Kouzu H, Miki T, Miura T
- Organizer
  American Heart Association BCVS
- Place of Presentation
  Las Vegas, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Mechanisms underlying mitochondrial translocation of GSK-3β, a crucial inducer of mitochondrial permeability transition : GSK-3βactivity, interaction with VDAC2 and a mitochondrial targeting sequence2013
- Author(s)
  Tanno M, Kuno A, Ishikawa S, Ogasawara M, Tobisawa T, Murase H, Sato T, Kouzu H, Miki T, Miura T
- Organizer
  Basic Cardiovascular Sciences 2013 (AHA)
- Place of Presentation
  Las Vegas, NV, U.S.A.
- Year and Date
  2013-07-23
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Mechanisms Underlying Mitochondrial Translocation Of GSK-3β, A Crucial Inducer Of Mitochondrial Permeability Transition: GSK-3β Activity, Interaction With VDAC2 And A Mitochondrial Targeting Sequence.2013
- Author(s)
  Tanno M, Kuno A, Ishikawa S, Ogasawara M, Tobisawa T, Murase H, Sato T, Kouzu H, Miki T, and Miura T
- Organizer
  American Heart Association BCVS 2013
- Place of Presentation
  Las Vegas, Nevada, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Role of SIRT3, a Mitochondrial Protein Deacetylase, in Type 2 Diabetic Myocardium2013
- Author(s)
  Kuno A, Itoh T, Sato T, Kouzu H, Tanno M, Miki T, Horio Y, Miura T
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-17
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Type 2 diabetes induces ventricular electrical remodeling with a transmural gradient2013
- Author(s)
  Tobisawa T, Sato T, Yuda S, Miki T, Tanno M, Kuno A, Kobayashi T, Akasaka H, Tohse N, Miura T
- Organizer
  European Society of Cardiology Congress 2013
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2013-09-02
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Insufficient ATP supply due to excessive degradation of adenine nucleotides underlies afterload-induced diastolic dysfunction in type 2 diabetic heart2013
- Author(s)
  Kouzu H, Miki T, Tanno M, Kuno A, Yano T, Murase H, Tobisawa T, Ogasawara M, Miura T
- Organizer
  第17回日本心不全学会
- Place of Presentation
  大宮
- Year and Date
  2013-11-30
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Changes in Titin-based Ventricular Stiffness May Underlie Diastolic Dysfunction Unmasked by Acute Systolic Pressure Overloading in Type 2 Diabetic Hearts2013
- Author(s)
  Kouzu H, Kuno A, Miki T, Tanno M, Itoh T, Sato T, Sunaga D, Murase H, Miura T
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Interaction with VDAC2 promotes mitochondrial translocation of GSK-3beta in a kinase activity-dependent manner and induces cell death.2013
- Author(s)
  Masaya Tanno,Takayuki Miki, Atsushi Kuno , Hidemichi Kouzu, Takahito Itoh , Tatsuya Satoh, Satoko Ishikawa, Daisuke Sunaga, Tetsuji Miura
- Organizer
  The 77th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Activation of the glucagon-like peptide-1 receptor restores myocardial autophagic flux and reduced mortality after myocardial infarction in diabetic rats2013
- Author(s)
  Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Tobisawa T, Ogasawara M, Ishikawa S, Miura T
- Organizer
  Scientific Sessions 2013, the American Heart Association
- Place of Presentation
  Dallas, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Type 2 diabetes induces ventricular electrical remode ling with a transmural gradient2013
- Author(s)
  Tobisawa T, Sato T, Yuda S, Miki T, Tanno M, Kuno A, Kobayashi T, Akasaka H, Tohse N, Miura T.
- Organizer
  European Society of Cardiology
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Interaction of Cyclophilin D with Inorganic Phosphate Carrier during Ischemia Determines Threshold for mPTP Opening and Reperfusion-induced Cell Necrosis2013
- Author(s)
  Ito T, Miki T, Tanno M, Kuno A, Kouzu H, Sato T, Sunaga D, Murase H, Ishikawa S, Miura T
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Mechanisms of mPTP re-closure by activation of the mitochondrial ATP-sensitive K+ channel : suppression of GSK-3β-Rieske interaction and ROS production after oxidative stress2013
- Author(s)
  Sunaga D, Tanno T, Ishikawa S, Kuno A, Sato T, Kouzu H, Miki T, Miura T
- Organizer
  The 50th International Society of Heart Research Japanese Section
- Place of Presentation
  San Diego, CA, U.S.A.
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Activation of the mitochondrial ATP-sensitive potassium channel achieves cell protection by promoting re-closure of the mPTP via suppression of GSK-3β-complex III interaction2013
- Author(s)
  Tanno M, Sunaga D, Miki T, Kuno A, Kouzu H, Sato T, Ishikawa S, Ogasawara M, Tobisawa T, Miura T
- Organizer
  European Society of Cardiology Congress 2013
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2013-09-03
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Insufficient ATP supply due to excessive degradation of adenine nucleotides underlies afterload - induced diastolic dysfu nction in type 2 diabetic heart2013
- Author(s)
  Kouzu H, Miki T, Tanno M, Kuno A, Yano T, Murase H, To bisawa T, Ogasawara M, Miura T
- Organizer
  日本心不全学会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Type 2 diabetes induces subendocardium-predominant reduction of transient outward K+ current via downregulation of Kv4.2 and KChIP22013
- Author(s)
  Sato T, Kobayashi T, Kuno K, Murase H, Kouzu H, Tanno T, Miki T, Miura T, Tohse N
- Organizer
  The 50th International Society of Heart Research Japanese Section
- Place of Presentation
  San Diego, CA, U.S.A.
- Year and Date
  2013-06-29
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Activation of the Glucagon-Like Peptide-1 Receptor Restores Myocardial Autophagic Flux and Reduces Mortality After Myocardial Infarction in Diabetic Rats2013
- Author(s)
  Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Tobisawa T, Ogasawara M, Ishikawa S, and Miura T.
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  Dallas, Texas, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Interaction with VDAC2 Promotes Mitochondrial Translocation of GSK3Βin a Kinase Activity-Dependent Manner and Induces Cell Death2013
- Author(s)
  Tanno M, Ishikawa S, Miki T, Kuno A, Kouzu H, Itoh T, Sato T, Sunaga D, Murase H, Miura T
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-03-16
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Interaction of cyclophilin D with inorganic phosphate carrier during ischemia determines threshold for mPTP opening and reperfusion-induced cell necrosis.2013
- Author(s)
  Takahito Ito,Hidemichi Kouzu , Takayuki Miki , Masaya Tanno , Atsushi Kuno , Tatsuya Satoh , Daisuke Sunaga , Hiromichi Murase , Satoko Ishikawa , Tetsuji Miura
- Organizer
  The 77th Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Activation of the glucagon-like peptide-1 receptor restores myocardial autophagic flux and reduces mortality after myocardial infarction in diabetic rats2013
- Author(s)
  Murase H, Kuno A, Miki T, Tanno M, Yano T, Kouzu H, Tobisawa T, Ogasawara M, Ishikawa S, Miura T
- Organizer
  American Heart Association 2013
- Place of Presentation
  Dallas, TX, U.S.A.
- Year and Date
  2013-11-17
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Interaction with VDAC2 promotes mitochondrial traslocation of GSK-3beta in a kinase activity-dependent manner and induces cell death2013
- Author(s)
  Tanno M, Miki T, Kuno A, Kouzu H, Itoh T, Sato T, Ishikawa S, Sunaga D, Miura
- Organizer
  The 77^<th> Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Activation of the mitochondrial ATP-sensitive potassium channel achieves cell protection by promoting re-closure of the mPTP via suppression of GSK-3beta - complex III interaction2013
- Author(s)
  Sunaga D, Tanno M, Miki T, Kuno A, Kouzu H, Sato T, Ishikawa S, Ogasawara M, Tobisawa T, and Miura T
- Organizer
  European Society of Cardiology Congress 2013
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] The Role of mTORC2 and Ribosomal Protein S6 in Cardioprotective Signaling2013
- Author(s)
  Yano T, Felito M, Tobisawa T, Ogasawara M, Murase H, Kuno A, Tanno M, Miki T, Steenbergen C, Miura T
- Organizer
  第17回日本心不全学会
- Place of Presentation
  大宮
- Year and Date
  2013-11-28
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Facilitated re-closure of the mitochondrial permeability transition pore underlies protection of cardiomyocytes from ROS-induced necrosis by activation of the mitochondrial ATP-sensitive K^+ channel2012
- Author(s)
  Suanga D, Kuno A, Ishikawa S, Miki T, Tanno M, Kouzu H, Itoh T, Sato T, Murase H, Miura T
- Organizer
  Scientific Sessions 2012, the American Heart Association
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Titin-isoform shift may underlie distinct ventricular responses to pressure and volume overloads in type 2 diabetic heart2012
- Author(s)
  Kouzu H, Kuno A, Miki T, Tanno M, Itoh T, Sato T, Sunaga D, Murase H, Miura T
- Organizer
  Scientific Sessions 2012, the American Heart Association
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Resveratrol, a SIRT1 activator, prevents cardiomyopathy in dystrophin-deficient mice by down-regulation of p3002012
- Author(s)
  Kuno A, Tanno M, Miki T, Ishikawa S, Horio Y, Miura T.
- Organizer
  European Society of Cardiology Congress 2012
- Place of Presentation
  Munich
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Titin-isoform Shift May Underlie Distinct Ventricular Responses to Pressure and Volume Overloads in Type 2 Diabetic Heart2012
- Author(s)
  Hidemichi Kouzu, Atsushi Kuno, Takayuki Miki, Masaya Tanno, Takahito Itoh, Tatsuya Sato, Daisuke Sunaga, Hiromichi Murase, and Tetsuji Miura
- Organizer
  Scientific Sessions 2012, the American Heart Assocaition
- Place of Presentation
  Los Angeles, CA, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] a SIRT1 activator, prevents cardiomyopathy in dystrophin-deficient mice by down- regulation of p3002012
- Author(s)
  Kuno A, Tanno M, Miki T, Ishikawa S, Horio Y, Miura T
- Organizer
  European Society of Cardiology Congress 2012
- Place of Presentation
  Munich, Germany
- Year and Date
  2012-08-26
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Phosphorylation of GSK-3b at Ser9 inhibits its translocation to mitochondria and attenuates lethal ROS production by mitochondria2012
- Author(s)
  Masaya Tanno, Takayuki Miki, Atsushi Kuno, Hidemichi Kouzu, Takahito Itoh, Tatsuya Sato, Daisuke Sunaga and Tetsuji Miura
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] UPR In Endoplasmic Reticulum vs. UPR In Mitochondria In Diabetic Myocardium: Which Is Responsible For Deficient Regulation Of Mitochondrial Permeability Transition Pores?2011
- Author(s)
  Itoh T, Kouzu H, Miki T, Tanno T, Kuno A, Sato T, Sunaga D, Ishikawa S, Miura T
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] GSK-3beta translocation to mitochodnria by oxidant stress in a kinase activity-dependent manner and contributes to lethal ROS production2011
- Author(s)
  Tanno M, Kuno A, Itoh T, Sato T, Ishikawa S, Sunaga D, Miura T
- Organizer
  Scientific Sessions 2011, the American Heart Association
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] GSK-3β Translocates to Mitochondria by Oxidant Stress in a Kinase Activity-Dependent Manner and Contributes to Lethal ROS Production2011
- Author(s)
  Tanno M, Kuno A, Kouzu H, Itoh T, Sato T, Ishikawa S, Sunaga D, Miura T.
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] GSK-3b translocates to mitochondria by oxidant stress in a kinase activity-dependent manner and contributes to lethal ROS production2011
- Author(s)
  Masaya Tanno, Takayuki Miki, Atsushi Kuno, Hidemichi Kouzu, Takahito Itoh, Tatsuya Sato, Daisuke Sunaga and Tetsuji Miura
- Organizer
  Scientific Sessions 2011, American Heart Association
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] UPR in endoplasmic reticulum vs. in mitochondria in diabetic myocardium : which is responsible for deficient regulation of mitochondrial permeability transition pores?2011
- Author(s)
  Itoh T, Kouzu H, Miki T, Tanno M, Kuno A, Sato T, Sunaga D, Ishikawa S, Miura
- Organizer
  Scientific Sessions 2011, the American Heart Association
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-23591086
[Presentation] Activation of Sirt1 suppresses hypertrophic response of cardiomyocytes by inhibition of H3K9 acetylation via p roteasome-mediated p300 degradation.2010
- Author(s)
  Kuno A, Tanno M, Ishikawa S, Horio Y, Miura T.
- Organizer
  83^<rd> Scientific Session of American Heart Association
- Place of Presentation
  Chicago,U.S.A.
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Activation of Sirtl suppresses hypertrophic response of cardiomyocytes by inhibition of H3K9 acetylation via proteasome-mediated p300 degradation.2010
- Author(s)
  Kuno A, Tanno M, Ishikawa S, Horio Y, Miura T.
- Organizer
  83^<rd> Scientific Sessions of American Heart Association.
- Place of Presentation
  Chicago, USA.
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Activation of Sirtl suppresses hypertrophic response of cardiomyocytes by inhibition of H3K9 acetylation via proteasome-mediated p300 degradation.2010
- Author(s)
  Masaya Tanno
- Organizer
  2010年度アメリカ心臓協会学術集会
- Place of Presentation
  アメリカ合衆国シカゴ
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Increased ER stress is a fundamental mechanism for impairment of cardioprotective signaling in type 2 diabetes.2010
- Author(s)
  Kouzu H, Itoh T, Miki T. Tanno M, Yano Y, Sato T, Takada A, Sunaga D, Miura T.
- Organizer
  83rd Scientific Sessions of American Heart Association.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Ventricular dysfunction and blunted response to adrenergic stimulation in obese type 2 diabetes predispose to fatal heart failure after infarction : Possible involvement of microRNA-1 down-regulation.2010
- Author(s)
  Takada A, Miki T Tanno M, Suzuki H, Yano T, Kuno A, Itoh T, Sato T, Miura T.
- Organizer
  83rd Scientific Sessions of American Heart Association.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Enhancement of cyclophilin-D-ANT interaction upon reperfusion in hypertensive hypertrophied hearts : a target of cardioprotection against ischemia/reperfusion injury.2010
- Author(s)
  Yano T, Tanno M Itoh T, Miura T.
- Organizer
  20th World Congress of the International Society for Heart Research.
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Mitochondria is a critical compartment for phospho-GSK-3β to afford cytoprotection against ischemia/reperfusion injury.2010
- Author(s)
  Sato T, Miura T, Tanno M, Miki T, Takada A, Itch T, Shimamoto K.
- Organizer
  20th World Congress of the International Society for Heart Research.
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Connexin43-dependent mitochondrial GSK-3β phosphorylation in protection of cardiomyocyte against necrosis.2010
- Author(s)
  Ishikawa S, Miki T, Tanno M, Miura T.
- Organizer
  20th World Congress of the International Society for Heart Research.
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Connexin-43 contributes to transmission of MitoK_ATP channel-derived redox signal to Akt-GSK-3β pathway in cardiomyocyte protection afforded by G protein-coupled receptors.2010
- Author(s)
  Ishikawa S, Kuno A, Miki T, Tanno T. Yano T, Kouzu H, Sato T, Sunaga D, Miura T.
- Organizer
  83rd Scientific Sessions of American Heart Association.
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Activation of histone/protein deacetylase SIRT1 by resveratrol induces MnSOD up-regulation via FOXO3a and improves survival of heart failure animals.2009
- Author(s)
  Kuno A, Tanno M, Miura T, Horio Y, Shimamoto K.
- Organizer
  31^<st> Congress of the European Society of Cardiology
- Place of Presentation
  Barcelona,Spain
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Enhanced ANT-cyclophilin-D interaction underlies reduced anti-infarct tolerance and loss of protective response to erythropoietin in hypertensive hypertrophied hearts.2009
- Author(s)
  Miki T. Yano T, Miura T, Tanno M. Shimamoto K.
- Organizer
  31st Congress of the European Society of Cardiology.
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] The SIRT1 activator resveratrol suppresses cardiomyocyte hypertrophy by promoting histone H3 Lys9 deacetylation and tri-methylation2009
- Author(s)
  Kuno A, Tanno M, et al.
- Organizer
  アメリカ心臓病学会
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Activation of histone/protein deacetylase SIRT1 by resveratrol induces MnSOD up-regulation via FOXO3a and improves survival of heart failure animals2009
- Author(s)
  Kuno A, Tanno M, et al.
- Organizer
  ヨーロッパ心臓病学会
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] The SIRT1 activator resveratrol suppresses cardiomy ocyte hypertrophy by promoting histone H3 Lys9 deacetylation and tri-methylation.2009
- Author(s)
  Kuno A, Tanno M, Yano T, Takada A, Miura T, Horio Y, Shimamoto K.
- Organizer
  82^<nd> Scientific Session of American Heart Association
- Place of Presentation
  Orlando, U.S.A.
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Role of GSK-3β in negative regulation of mitochondrial permeability transition pore by the mitochondrial K_ATP channel.2009
- Author(s)
  Miura T, Terashima Y, Maas O, Miki T, Tanno M, Ishikawa S, Shimamoto K.
- Organizer
  31st Congress of the European Society of Cardiology.
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Resveratrol, a SIRT1 activator, modifies epigenetic histone acetylation/methylation status and suppresses cardiomyocyte hypertrophy2009
- Author(s)
  Kuno A, Tanno M, et al.
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Activation of histone/protein deacetylase SIRTI by resveratrol induces MnSOD upregulation via FOXO3a and improves survival of heart failure animals.2009
- Author(s)
  Kuno A, Tanno M. Miura T, Horio Y, Shimamoto K.
- Organizer
  31st Congress of the European Society of Cardiology.
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Activation of a protein deacetylase, SIRTl, by resveratrol suppresses progression of heart failure and improves survival by up-regulation of MnSOD2008
- Author(s)
  Masaya Tanno
- Organizer
  Scientific Sessions 2008 of the American Heart Association
- Place of Presentation
  New Orleans, USA
- Year and Date
  2008-11-10
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Resveratrol, an activator of protein deacetylase SIRT1, suppresses oxidative stress-induced cell death by upregulating MnSOD expression through transactivation of Foxo3a.2008
- Author(s)
  Kuno A, Tanno M Miura T, Horio Y, Shimamoto K.
- Organizer
  81st Scientific Sessions of American Heart Association.
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] ER stress contributes to dysregulation of GSK-3β-mediated suppression of mitochondrial permeability transition in diabetic hearts.2008
- Author(s)
  Miki T, Tanno M, Kuno A, Yano T, Sato T, Hotta H, Ichikawa S, Miura T.
- Organizer
  81st Scientific Sessions of American Heart Association.
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Resveratrol, an activator of protein deacetylase SIRT1, suppresses oxidative stress-induced cell death by upregulating MnSOD expression through transactivation of FOXO3a .2008
- Author(s)
  Kuno A, Tanno M, Miura T, Horio Y, Shimamoto K.
- Organizer
  81^<st> Scientific Session of America n Heart Association
- Place of Presentation
  New Orleans,U.S.A.
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Connexin43-dependent and-independent mechanisms of mitochondrial GSK-3β phosphorylation in protection of cardiomyocyte against necrosis.2008
- Author(s)
  Ishikawa S, Miura T, Tanno M, Kuno A, Sato T, Hotta H, Terashima Y, Miki T.
- Organizer
  81st Scientific Sessions of American Heart Association.
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] Activation of a protein deacetylase,SIRT1, by resveratrol suppresses progression of heart failure and improves survival by up-regulation of Mn-SOD.2008
- Author(s)
  Tanno M, Kuno A, Miki T, Miura T, Horio Y, Shimamoto K.
- Organizer
  81^<st> Scientific Session of American Heart Association
- Place of Presentation
  New Orleans, U.S.A.
- Data Source
  KAKENHI-PROJECT-20590869
[Presentation] Activation of a protein deacetylase, SIRTI, by Resveratol suppresses progression of heart failure and improves survival by up-regulation of Mn-SOD.2008
- Author(s)
  Tanno M Kuno A, Miki T. Miura T. Horio Y, Shimamoto K.
- Organizer
  81st Scientific Sessions of American Heart Association.
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-20590870
[Presentation] 心不全発症進展における長寿蛋白SIRT1の機能とその分子機序
- Author(s)
  丹野雅也
- Organizer
  日本適応医学会第15回学術集会(招待講演)
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23591085
[Presentation] Mitochondrial translocation of GSK-3β, a trigger of mitochondrial permeability transition, is mediated by its N-terminal domain and promoted by interaction with VDAC2.
- Author(s)
  Tanno M, Ishikawa S, Miki T, Kuno A, Kouzu H, Yano T, Miura T
- Organizer
  Frontiers in Cardiovascular Biology, 3rd meeting of the ESC council on basic cardiovascular science
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2014-07-04 – 2014-07-06
- Data Source
  KAKENHI-PROJECT-26461132
[Presentation] Accumulation of p62 by dysregulation of autophagy induces RIP1-dependent necroptosis in cardiomyocytes: a novel interplay between autophagy and necroptosis.
- Author(s)
  Ogasawara M, Yano T, Miki T, Tanno M, Kuno A, Kouzu H, Murase H, Tobisawa T, Muratsubaki S, Nishizawa K, Mizuno M, Ishikawa S, Miura T.
- Organizer
  American Heart Association, Scientific Sessions 2014
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26461133

1. MIURA Tetsuji (90199951)

# of Collaborated Projects: 9 results

# of Collaborated Products: 117 results
2. Yano Toshiyuki (40444913)

# of Collaborated Projects: 7 results

# of Collaborated Products: 61 results
3. MIKI Takayuki (00336405)

# of Collaborated Projects: 5 results

# of Collaborated Products: 60 results
4. 久野篤史 (30468079)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
5. HORIO Yoshiyuki (30181530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
6. Moniwa Norihito (50749786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 佐藤達也

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 神津英至

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Tanno Masaya 丹野 雅也

TANNO Masaya 丹野 雅也

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Mechanisms underlying regulation of AMP deaminase activity and its involvement in the pathophysiology of diabetic cardiomyopathyPrincipal Investigator

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Development of novel therapeutic approach for diabetic cardiomyopathy by modification of AMP deaminase activity.Principal Investigator

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Novel therapeutic approach for heart failure by suppression of mitochondrial translocation of GSK-3betaPrincipal Investigator

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Novel therapeutic approach for heart failure by promoting nuclear translocation of SIRT1, a protein deacetylasePrincipal Investigator

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Clarification of mechanisms to regulate the activity of protein deacetylase SIRT1 and its therapeutic application in heart failurePrincipal Investigator

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Tanno Masaya 丹野雅也

TANNO Masaya 丹野雅也