Yaguchi Hiroaki 矢口裕章

Researcher Number	00421975
Other IDs	https://orcid.org/0000-0001-6643-8740
Affiliation (Current)	2025: 北海道大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 北海道大学, 医学研究院, 准教授 2020: 北海道大学, 医学研究院, 客員研究員 2013 – 2015: 北海道大学, 医学(系)研究科(研究院), 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Basic Section 51030:Pathophysiologic neuroscience-related / Neurology Except Principal Investigator Basic Section 52020:Neurology-related
Keywords	Principal Investigator Sez6l2 / 脳炎 / 認知症 / 小脳性運動失調症 / 自己免疫性小脳失調症 / 自己免疫性脳炎 / 自己抗体 / 小脳失調 / 抗神経抗体 / Sez6l2抗体 … More / てんかん / 免疫介在 / 神経免疫 / 小脳失調症 / 傍主要性症候群 … More Except Principal Investigator Bassoon / タウオパチー / ELISA / 抗神経抗体 / 自己免疫性脳炎 / tauopathy / ubiquitin / 進行性核上性麻痺 / Bassoon proteinopathy / モデル動物 / パーキンソニズム / 認知症 / 神経変性 / バイオマーカー / 多発性硬化症 / 多系統萎縮症 / BSN遺伝子変異 / ノックインマウス / BSN proteinopathy / パーキンソン症候群 Less

Mechanism analysis research of Bassoon proteinopathy
- Principal Investigator
  
  矢部一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
Analysis research of anti-Sez6l2 antibody associated encephalopathyPrincipal Investigator
- Principal Investigator
  
  矢口裕章
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
自己免疫性脳炎における抗神経抗体のCBAに代わる新規迅速・定量的測定法の開発
- Principal Investigator
  
  松永晶子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  University of Fukui
Autoantibody analysis study in cerebellar ataxiaPrincipal Investigator
- Principal Investigator
  
  Yaguchi Hiroaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Hokkaido University
Pathophysiological study of Bassoon proteinopathy
- Principal Investigator
  
  Yabe Ichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
Identification of auto-antibody in cerebellar ataxiaPrincipal Investigator
- Principal Investigator
  
  Yaguchi Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurology
- Research Institution
  Hokkaido University

All 2024 2023 2022 2021 2016 2013

All Journal Article Presentation Book

[Book] 自己免疫性脳炎・関連疾患ハンドブック（Ⅱ章12）2023
- Author(s)
  矢口裕章
- Total Pages
  363
- Publisher
  金芳堂
- ISBN
  9784765319560
- Data Source
  KAKENHI-PROJECT-20K16481
[Journal Article] Invited Review Article Autoimmune Cerebellar Ataxia2023
- Author(s)
  Yaguchi H, Kudo A, Yabe I
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: - Issue: 4 Pages: 159-166
- DOI
  10.1111/cen3.12752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16481
[Journal Article] Sez6l2 autoimmunity in a large cohort study2023
- Author(s)
  Megumi Abe, Hiroaki Yaguchi, Ichiro Yabe, et al.
- Journal Title
  
  Journal of Neurology, Neurosurgery, and Psychiatry
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16481
[Journal Article] Immune-mediated Cerebellar Ataxia with Neurosarcoidosis2023
- Author(s)
  Mizushima K, Yaguchi H, Sato S, Yabe I.
- Journal Title
  
  Intern. Med.
  
  Volume: 62 Issue: 13 Pages: 2023-2024
- DOI
  10.2169/internalmedicine.0784-22
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2023-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16481
[Journal Article] A retrospective study of autoimmune cerebellar ataxia over a 20-year period in a single institution2023
- Author(s)
  Kudo Akihiko、Yaguchi Hiroaki、Tanaka Keiko、Kimura Akio、Yabe Ichiro
- Journal Title
  
  Journal of Neurology
  
  Volume: 271 Issue: 1 Pages: 553-563
- DOI
  10.1007/s00415-023-11946-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06940, KAKENHI-PROJECT-21K07457
[Journal Article] Bassoon proteinopathy2021
- Author(s)
  脇田雅大、長井梓、矢口裕章、矢部一郎
- Journal Title
  
  脳神経内科
  
  Volume: 95 Pages: 482-488
- NAID
  40022724771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03585
[Journal Article] Identification of anti-Sez6l2 antibody in a patient with cerebellar ataxia and retinopathy2013
- Author(s)
  Yaguchi H, Yabe I, Takahashi H, Okumura F, Takeuchi A, Horiuchi, K, Kan T, Kanda, A, Saito W, Matsumoto M, Nakayama KI, Hatakeyama S and Sasaki H
- Journal Title
  
  J. Neurol.
  
  Volume: 261 Issue: 1 Pages: 224-226
- DOI
  10.1007/s00415-013-7134-5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-24659121, KAKENHI-PROJECT-24689016, KAKENHI-PROJECT-24791823, KAKENHI-PUBLICLY-25118501, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25893006
[Presentation] Sez6l2抗体陽性自己免疫性小脳失調症例のまとめ2024
- Author(s)
  矢口裕章、阿部恵、工藤彰彦、藤井信太朗、野村太一、上床尚、白井慎一、岩田育子, 松島理明, 竹腰顕、木村暁夫、下畑享良、矢部一郎
- Organizer
  日本小脳学会　第14回学術大会　総会
- Data Source
  KAKENHI-PROJECT-23K06940
[Presentation] Pathological study of PSP-like syndrome cases with mutations in BSN and BSN knock-in mice2023
- Author(s)
  Hiroaki Yaguchi, Masahiro Wakita, Mika Otuski, Satoshi Tanikawa, Yasuo Miki, Akihiko Kudo, Azusa Nagai, Hisashi Uwatoko, Yasunori Mito, Kaichi Yoshizaki, Taichi Hara, Takeshi Ikeuchi, Shinya Tanaka, Koichi Wakabayashi, Ichiro Yabe
- Organizer
  日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27511
[Presentation] Sez6l2抗体陽性免疫介在性小脳性運動失調症についての検討2022
- Author(s)
  矢部一郎，〇矢口裕章，阿部　恵，木村暁夫，下畑享良
- Organizer
  令和3年度厚生労働省科学研究費補助金　難治性疾患等政策研究事業（難治性疾患政策研究事業）「運動失調症の医療水準，患者QOLの向上に資する研究班」研究報告会
- Data Source
  KAKENHI-PROJECT-20K16481
[Presentation] BSN遺伝子変異例におけるタンパク質品質管理の病理学的検討とモデルマウス作製2022
- Author(s)
  矢口裕章，脇田雅大, 長井　梓，白井慎一,岩田育子,松島理明,三木康生，原　太一，吉崎嘉一，高橋秀尚，若林　孝一,矢部一郎
- Organizer
  第63回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03585
[Presentation] Japanese cases of Sez6l2 autoimmunity2022
- Author(s)
  Abe M, Yaguchi H, Kudo A, Yabe I, et al
- Organizer
  International Congress of Parkinson’s Disease and Movement Disorders
- Data Source
  KAKENHI-PROJECT-20K16481
[Presentation] Detection of specific antigens in immune-mediated cerebellar ataxias2022
- Author(s)
  Kudo A, Yaguchi H, Yabe I, et al
- Organizer
  International Congress of Parkinson’s Disease and Movement Disorders
- Data Source
  KAKENHI-PROJECT-20K16481
[Presentation] Sez6l2抗体と小脳性運動失調症2022
- Author(s)
  矢口裕章、阿部恵、矢部一郎
- Organizer
  第63回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K16481
[Presentation] 治療可能な神経疾患としての免疫介在性小脳性運動失調症～早期診断・早期治療を目指して～2022
- Author(s)
  矢口裕章、工藤彰彦、阿部恵、矢部一郎
- Organizer
  第40回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16481
[Presentation] 免疫介在性小脳性運動失調症における抗Sez6l2抗体の検討2021
- Author(s)
  阿部　恵，矢口裕章，長井　梓，白井慎一，岩田育子，松島理明，芦田真士，笠井高士，木村暁夫，下畑享良，矢部一郎
- Organizer
  第33回日本神経免疫学会学術大会
- Data Source
  KAKENHI-PROJECT-20K16481
[Presentation] Mutation analysis of BSN gene in patients with multiple system atrophy2021
- Author(s)
  M. Wakita, A. Nagai, H. Yaguchi, I. Yabe.
- Organizer
  MDS Virtual Congress 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03585
[Presentation] 抗神経抗体抗原であるSez6l2はAMPA受容体とADDの複合体を形成しシグナル伝達を促進する2016
- Author(s)
  矢口　裕章
- Organizer
  第27回日本神経免疫学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜県・岐阜市）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-25893006
[Presentation] Identification of anti-Sez6l2 antibody in a patient with cerebellar ataxia and retinopathy.2013
- Author(s)
  矢口　裕章
- Organizer
  分子生物学会
- Place of Presentation
  神戸ポートアイランド（神戸）
- Data Source
  KAKENHI-PROJECT-25893006

1. 高橋秀尚 (30423544)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. Yabe Ichiro (60372273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 原太一 (00392374)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 池内健 (20372469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 若林孝一 (50240768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 大塚稔久 (40401806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 畠山鎮次 (70294973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 松島理明 (10443938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 近藤豪 (10712705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松永晶子 (40401971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 米田誠 (70270551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yaguchi Hiroaki 矢口 裕章

Research Projects

Research Products

Co-Researchers

Mechanism analysis research of Bassoon proteinopathy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis research of anti-Sez6l2 antibody associated encephalopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自己免疫性脳炎における抗神経抗体のCBAに代わる新規迅速・定量的測定法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autoantibody analysis study in cerebellar ataxiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological study of Bassoon proteinopathy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of auto-antibody in cerebellar ataxiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 自己免疫性脳炎・関連疾患ハンドブック（Ⅱ章12）2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Invited Review Article Autoimmune Cerebellar Ataxia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sez6l2 autoimmunity in a large cohort study2023

Author(s)

Journal Title

Data Source

[Journal Article] Immune-mediated Cerebellar Ataxia with Neurosarcoidosis2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] A retrospective study of autoimmune cerebellar ataxia over a 20-year period in a single institution2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bassoon proteinopathy2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Identification of anti-Sez6l2 antibody in a patient with cerebellar ataxia and retinopathy2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Sez6l2抗体陽性自己免疫性小脳失調症例のまとめ2024

Author(s)

Yaguchi Hiroaki 矢口裕章

[Presentation] Sez6l2抗体陽性免疫介在性小脳性運動失調症についての検討2022