Hara Taichi 原太一

… Alternative Names

HARA Taichi 原太一

原太一ハラタイチ

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Researcher Number	00392374
Other IDs
Affiliation (Current)	2025: 早稲田大学, 人間科学学術院, 教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 早稲田大学, 人間科学学術院, 教授 2012 – 2016: 群馬大学, 生体調節研究所, 准教授 2007: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助手 2005: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 38050:Food sciences-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 47060:Clinical pharmacy-related / Biological Sciences / Cell biology Except Principal Investigator Basic Section 52020:Neurology-related / Biological Sciences / Basic Section 59040:Nutrition science and health science-related / Basic Section 38030:Applied biochemistry-related … More / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 44010:Cell biology-related / Cell biology Less
Keywords	Principal Investigator 細胞膜タンパク質 / 初期胚発生 / オートファジー / リソソーム / 神経難病 / Rer1 / 小胞体 / ゴルジ体 / 脳 / 遺伝子欠損マウス … More / 細胞内膜輸送 / メンブレントラフィック / フィトケミカル / 液滴 / p62 / 希少難病 / 変死膜タンパク質 / 疾患モデルマウス / 変異膜たんぱく質 / 天然医薬資源 / 神経変性疾患 / PMP22 / CMT病 / 生薬 / 変異膜タンパク質 / 蛋白質 / 発生・分化 / 細胞・組織 / 脳神経疾患 / 膜タンパク質 / γ-secretase / 大脳発生 / 大脳形成 / 神経幹細胞 / タンパク質品質管理 / 初期ゴルジ / Notchシグナル / γセクレターゼ / 多能性幹細胞 / 小胞体品質管理 / 神経発生 / マウス初期胚発生 / 疾患関連変異膜タンパク質 / タンパク質品質管理機構 / 神経 / Rab / 低分子量Gタンパク質 / 初期発生 / 神経細胞 / Rab35 / エンドサイトーシス / ES細胞 / 制御 / ATP / Atg / AMPK … More Except Principal Investigator ユビキチン / Bassoon / タウオパチー / バイオマーカー / 糖尿病 / DIF / 細胞性粘菌 / マウス / 封入体 / タンパク質凝集体 / タンパク質品質管理 / オートファジー / エネルギー代謝 / オルガネラ / GPCR / tauopathy / ubiquitin / 進行性核上性麻痺 / Bassoon proteinopathy / D. discoideum / 肥満 / モデル動物 / パーキンソニズム / 認知症 / 神経変性 / 多発性硬化症 / 多系統萎縮症 / BSN遺伝子変異 / ノックインマウス / BSN proteinopathy / パーキンソン症候群 / 生理活性因子 / 酸化ストレス / 分子メカニズム / BDNF / 加齢 / 炎症 / うつ / 脳 / 機能性食品 / マイクロRNA / エクソソーム / 分子生物学的解析 / 骨格筋 / 運動 / 抗菌剤 / 天然物化学 / 糖代謝 / 創薬 / マラリア / 抗菌薬 / 抗がん剤 / 細胞分化 / 細胞周期 / 骨格筋分化 / Cdon / Cdo / ZSWIM8 / タンパク質分解 / 筋分化 / 膜トラフィック / 細胞内分解 / 線虫 / メンブレントラフィック / オルガネラ形成・動態 / 分解 / エンドサイトーシス / 受精 / ノックアウトマウス / 神経変性疾患 Less

細胞内液滴を基盤としたポリフェノールによる統合的ストレス制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  原太一
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Waseda University
細胞性粘菌由来化合物をリードとした新規肥満治療薬・糖尿病治療薬の開発
- Principal Investigator
  
  久保原禅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Juntendo University
D-アミノ酸によるオートファジー誘導機構の解明と健康制御への応用Principal Investigator
- Principal Investigator
  
  原太一
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Waseda University
Mechanism analysis research of Bassoon proteinopathy
- Principal Investigator
  
  矢部一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
GPRC6Aシグナリングによるオルガネラの恒常性維持機構の解明
- Principal Investigator
  
  向井悟
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  University of East Asia
Investigation of exercise effects by bioactive factors secreted by skeletal muscle and biomarker development
- Principal Investigator
  
  Suzuki Katsuhiko
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Waseda University
Development of innovative treatments for rare and intractable diseases based on natural pharmaceutical resourcesPrincipal Investigator
- Principal Investigator
  
  Hara Taichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Waseda University
Pathophysiological study of Bassoon proteinopathy
- Principal Investigator
  
  Yabe Ichiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hokkaido University
Drug development using biologically active substances derived from D. discoideum as seeds
- Principal Investigator
  
  Kubohara Yuzuru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Juntendo University
The regulation of cell division and cell differentiation by the Elongin BC-type ubiquitin ligase
- Principal Investigator
  
  Okumura Fumihiko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Fukuoka Women's University
  Nagoya University
Molecular pathogenesis of neurological diseases caused by disruption of early Golgi quality control systemPrincipal Investigator
- Principal Investigator
  
  Hara Taichi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Waseda University
Physiological role and molecular mechanism of early Golgi quality control systemPrincipal Investigator
- Principal Investigator
  
  Hara Taichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
Analysis of spaciotemporal regulation mechanisms for intracellular membrane remodeling in embryos
- Principal Investigator
  
  Sato Ken
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Gunma University
初期胚発生と連動した細胞膜タンパク質の分解制御機構と生理的役割の解明Principal Investigator
- Principal Investigator
  
  原太一
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Analysis of physiological roles of membrane trafficking in neural functionPrincipal Investigator
- Principal Investigator
  
  HARA Taichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Gunma University
神経変性疾患の病態形成におけるオートファジーの役割
- Principal Investigator
  
  水島昇
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
オートファジーによる細胞内タンパク質の品質管理
- Principal Investigator
  
  水島昇
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
  Tokyo Metropolitan Organization for Medical Research
哺乳類オートファジー制御シグナルの解明Principal Investigator
- Principal Investigator
  
  原太一
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Medical and Dental University
  Tokyo Metropolitan Organization for Medical Research

[Book] 人間科学で読み解く幸せな認知症　認知症の人は「恍惚の人」ではない2022
- Author(s)
  加瀬裕子、大須理英子、加藤麻樹、倉片憲治、榊原伸一、千葉卓哉、永島計、原太一
- Total Pages
  122
- Publisher
  株式会社　ワールドプランニング
- ISBN
  9784863512252
- Data Source
  KAKENHI-PROJECT-20H03408
[Book] 神経変性疾患におけるオートファジーの役割「神経変性疾患のサイエンス」高橋良輔編2007
- Author(s)
  原太一
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18023043
[Book] 細胞工学2006
- Author(s)
  原太一, 水島昇
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-17770175
[Book] 蛋白質核酸酵素2006
- Author(s)
  原太一, 水島昇
- Total Pages
  6
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17770175
[Journal Article] <i>Dictyostelium</i> Differentiation-inducing Factor Derivatives Reduce the Glycosylation of PD-L1 in MDA-MB-231 Human Breast Cancer Cells2023
- Author(s)
  Airi Hirayama, Hirotaka Ishigaki, Katsunori Takahashi, Yusuke Miura, Haruhisa Kikuchi, Yuzuru Kubohara
- Journal Title
  
  Juntendo Medical Journal
  
  Volume: 69 Issue: 2 Pages: 105-115
- DOI
  10.14789/jmj.JMJ22-0039-OA
- ISSN
  2187-9737, 2188-2126
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07139
[Journal Article] Novel function of Moringa oleifera Lam. leaf extract: cytoprotection against proteotoxic stress2023
- Author(s)
  Satoshi Yano, Shiori Sasaki, Shengai Jin, Nanako Shibata, Kaoru Kataoka, Wakana Matsushita, Yuka Sugaya, Shota Yamakoshi, Taichi Hara
- Journal Title
  
  New Food Industry
  
  Volume: 65 Pages: 501-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H00574
[Journal Article] RAB35 is required for murine hippocampal development and functions by regulating neuronal cell distribution2023
- Author(s)
  Maejima Ikuko、Hara Taichi、Tsukamoto Satoshi、Koizumi Hiroyuki、Kawauchi Takeshi、Akuzawa Tomoko、Hirai Rika、Kobayashi Hisae、Isobe Inoya、Emoto Kazuo、Kosako Hidetaka、Sato Ken
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 440-440
- DOI
  10.1038/s42003-023-04826-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05678, KAKENHI-PROJECT-20H00574
[Journal Article] RNA-binding protein LIN28A upregulates transcription factor HIF1α by posttranscriptional regulation via direct binding to UGAU motifs2023
- Author(s)
  Yamamoto Hiroto、Uchida Yutaro、Kurimoto Ryota、Chiba Tomoki、Matsushima Takahide、Ito Yoshiaki、Inotsume Maiko、Miyata Kohei、Watanabe Kenta、Inada Masaki、Goshima Naoki、Uchida Tokujiro、Asahara Hiroshi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 1 Pages: 102791-102791
- DOI
  10.1016/j.jbc.2022.102791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07444, KAKENHI-PROJECT-22K05490, KAKENHI-PROJECT-20H05696, KAKENHI-PROJECT-20H00574, KAKENHI-PROJECT-20H02534, KAKENHI-PROJECT-19KK0194, KAKENHI-PROJECT-23K24722, KAKENHI-PROJECT-22K07226
[Journal Article] Genome-Wide RNA Sequencing Analysis in Human Dermal Fibroblasts Exposed to Low-Dose Ultraviolet A Radiation2022
- Author(s)
  Wang Jinyun、Yano Satoshi、Xie Kun、Ohata Yoshihisa、Hara Taichi
- Journal Title
  
  Genes
  
  Volume: 13 Issue: 6 Pages: 974-974
- DOI
  10.3390/genes13060974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17816, KAKENHI-PROJECT-20H03408
[Journal Article] シダ植物イワヒバ由来成分の表皮角化細胞に対する細胞増殖と紫外線ストレス保護作用の検討2022
- Author(s)
  関根結夏子, 塩田皐希, 矢野敏史, 原太一
- Journal Title
  
  薬理と治療
  
  Volume: 50(4) Pages: 527-533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] Proteomic profiling of intestinal epithelial‐like cell‐derived exosomes regulated by epigallocatechin gallate2022
- Author(s)
  Yano Satoshi、Suzuki Katsuhiko、Hara Taichi
- Journal Title
  
  BioFactors
  
  Volume: 49 Issue: 2 Pages: 390-404
- DOI
  10.1002/biof.1918
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00574, KAKENHI-PROJECT-22K17816
[Journal Article] Dictyostelium Differentiation-Inducing Factor-1 Promotes Glucose Uptake, at Least in Part, via an AMPK-Dependent Pathway in Mouse 3T3-L1 Cells2021
- Author(s)
  Kubohara Yuzuru、Homma Yoshimi、Shibata Hiroshi、Oshima Yoshiteru、Kikuchi Haruhisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 5 Pages: 2293-2293
- DOI
  10.3390/ijms22052293
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07139
[Journal Article] 植物由来微生物およびヒノキ樽に生息する微生物がもたらす自然発酵による食品の機能性とその実態2021
- Author(s)
  本藤和彦, 馬場亜沙美, 原太一, 和泉達也, 吉田雄介
- Journal Title
  
  New Food Industry
  
  Volume: 63(2) Pages: 93-152
- NAID
  40022478273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] Derivatives of Dictyostelium differentiation-inducing factors suppress the growth of Plasmodium parasites in vitro and in vivo.2021
- Author(s)
  Mita T, Hirai M, Maki Y, Nahar S, Yoshida N, Oshima Y, Kikuchi H, Kubohara Y.
- Journal Title
  
  Biochem Pharmacol
  
  Volume: - Pages: 114834-114834
- DOI
  10.1016/j.bcp.2021.114834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04074, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-19K07139, KAKENHI-PROJECT-20K07466
[Journal Article] Electrolyzed Hydrogen Water Protects against Ethanol-Induced Cytotoxicity by Regulating Aldehyde Metabolism-Associated Enzymes in the Hepatic Cell Line HepG2.2021
- Author(s)
  Yano S, Wang J, Kabayama S, Hara T.
- Journal Title
  
  Antioxidants (Basel).
  
  Volume: 10(5) Issue: 5 Pages: 801-801
- DOI
  10.3390/antiox10050801
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation2021
- Author(s)
  Okumura Fumihiko、Oki Nodoka、Fujiki Yuha、Ikuta Rio、Osaki Kana、Hamada Shun、Nakatsukasa Kunio、Hisamoto Naoki、Hara Taichi、Kamura Takumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20880-20880
- DOI
  10.1038/s41598-021-00306-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-20H03408, KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-19H02923
[Journal Article] 植物発酵液SW（低分子コラーゲン含有）の摂取が女性の美白・美肌に及ぼす影響と安全性の検証：非盲検試験2020
- Author(s)
  本藤和彦, 山下慎一郎, 鈴木直子, 原太一, 和泉達也
- Journal Title
  
  薬理と治療
  
  Volume: 62(5) Pages: 311-324
- NAID
  40022247069
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] High fat diet enhances working memory in the Y-maze test in male 57BL/6J mice with less anxiety in the elevated plus maze test.2020
- Author(s)
  Yoshizaki Kaichi, Asai Masato, Hara Taichi
- Journal Title
  
  Nutrients
  
  Volume: 12(7) Issue: 7 Pages: 2036-2036
- DOI
  10.3390/nu12072036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08060, KAKENHI-PROJECT-20H03408
[Journal Article] 植物発酵液SWのメラニン産生抑制効果に関する研究2020
- Author(s)
  及川哲志, 原太一
- Journal Title
  
  薬理と治療
  
  Volume: 48(7) Pages: 1151-1158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] Bilberry Anthocyanins Ameliorate NAFLD by Improving Dyslipidemia and Gut Microbiome Dysbiosis2020
- Author(s)
  Nakano Hironobu、Wu Shusong、Sakao Kozue、Hara Taichi、He Jianhua、Garcia Santos、Shetty Kalidas、Hou De-Xing
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 11 Pages: 3252-3252
- DOI
  10.3390/nu12113252
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05931, KAKENHI-PROJECT-20K05928, KAKENHI-PROJECT-20H03408
[Journal Article] Two New Terpenes Isolated from Dictyostelium Cellular Slime Molds2020
- Author(s)
  Sasaki Hitomi、Kubohara Yuzuru、Ishigaki Hirotaka、Takahashi Katsunori、Eguchi Hiromi、Sugawara Akihiro、Oshima Yoshiteru、Kikuchi Haruhisa
- Journal Title
  
  Molecules
  
  Volume: 25 Issue: 12 Pages: 2895-2895
- DOI
  10.3390/molecules25122895
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02837, KAKENHI-PROJECT-19H03701, KAKENHI-PROJECT-19K07139
[Journal Article] 酵母発酵にんにくのマウスの受精と初期胚発生に及ぼす影響の検討2020
- Author(s)
  吉崎嘉一, 矢野敏史, 諸富勝成, 久保田拓海, 原太一
- Journal Title
  
  薬理と治療
  
  Volume: 48(7) Pages: 1145-1150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] Identification of Dietary Phytochemicals Capable of Enhancing the Autophagy Flux in HeLa and Caco-2 Human Cell Lines2020
- Author(s)
  Ohnishi Kohta、Yano Satoshi、Fujimoto Moe、Sakai Maiko、Harumoto Erika、Furuichi Airi、Masuda Masashi、Ohminami Hirokazu、Yamanaka-Okumura Hisami、Hara Taichi、Taketani Yutaka
- Journal Title
  
  Antioxidants
  
  Volume: 9 Issue: 12 Pages: 1193-1193
- DOI
  10.3390/antiox9121193
- NAID
  120007042435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21761, KAKENHI-PROJECT-20K19675, KAKENHI-PROJECT-19H04053, KAKENHI-PROJECT-20H03408, KAKENHI-PROJECT-20H04038
[Journal Article] Autophagy in Health and Food Science2020
- Author(s)
  Satoshi Yano, Jinyun Wang, Taichi Hara
- Journal Title
  
  Current Pharmacology Reports
  
  Volume: 6(6) Issue: 6 Pages: 335-345
- DOI
  10.1007/s40495-020-00237-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] ヒト線維芽細胞の酸化ストレス障害およびコラーゲン遺伝子発現に及ぼす植物発酵液SWの影響2020
- Author(s)
  矢野敏史, 及川哲志, 大畑佳久, 本藤和彦, 山下慎一郎, 鈴木直子, 原太一
- Journal Title
  
  薬理と治療
  
  Volume: 48(7) Pages: 1159-1165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03408
[Journal Article] Isorhamnetin, a 3’-methoxylated flavonol, enhances the lysosomal proteolysis in J774.1 murine macrophages in a TFEB-independent manner.2020
- Author(s)
  Sakai Maiko、Ohnishi Kohta、Masuda Masashi、Ohminami Hirokazu、Yamanaka-Okumura Hisami、Hara Taichi、Taketani Yutaka
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 84 Issue: 6 Pages: 1221-1231
- DOI
  10.1080/09168451.2020.1727309
- NAID
  130008108983
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K19675, KAKENHI-PROJECT-19H04053, KAKENHI-PROJECT-20H04038, KAKENHI-PROJECT-17K08621, KAKENHI-PROJECT-18K17946, KAKENHI-PROJECT-22KJ2350
[Journal Article] Antimicrobial Activities of Dictyostelium Differentiation-Inducing Factors and Their Derivatives2019
- Author(s)
  Kubohara Yuzuru、Shiratsuchi Yoshiko、Ishigaki Hirotaka、Takahashi Katsunori、Oshima Yoshiteru、Kikuchi Haruhisa
- Journal Title
  
  Biomolecules
  
  Volume: 9 Issue: 5 Pages: 163-163
- DOI
  10.3390/biom9050163
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03701, KAKENHI-PROJECT-19K07139
[Journal Article] Halogen-Substituted Derivatives of Dictyostelium Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro2019
- Author(s)
  Kyoko Totsuka、Yuka Makioka、Kyoichi Iizumi、Katsunori Takahashi、Yoshiteru Oshima、Haruhisa Kikuchi、Yuzuru Kubohara
- Journal Title
  
  Biomolecules
  
  Volume: 9 Issue: 7 Pages: 256-256
- DOI
  10.3390/biom9070256
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02837, KAKENHI-PROJECT-19H03701, KAKENHI-PROJECT-19K07139
[Journal Article] Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse2018
- Author(s)
  Tatsumi Takayuki、Takayama Kaori、Ishii Shunsuke、Yamamoto Atsushi、Hara Taichi、Minami Naojiro、Miyasaka Naoyuki、Kubota Toshiro、Matsuura Akira、Itakura Eisuke*、Tsukamoto Satoshi*
- Journal Title
  
  Development
  
  Volume: 145 Issue: 4 Pages: 161893-161893
- DOI
  10.1242/dev.161893
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01194, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-16H05042, KAKENHI-PROJECT-15H05637, KAKENHI-PROJECT-16H06167, KAKENHI-PROJECT-17K08621
[Journal Article] Rer1-mediated quality control system is required for neural stem cell maintenance during cerebral cortex development2018
- Author(s)
  Taichi Hara, Ikuko Maejima, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, Satoshi Tsukamoto, Mika Tsunoda, Aguri Ono, Shota Yamakoshi, Satoshi Oikawa and Ken Sato
- Journal Title
  
  PLoS Genetics
  
  Volume: 14(9) Issue: 9 Pages: e1007647-e1007647
- DOI
  10.1371/journal.pgen.1007647
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08621, KAKENHI-PROJECT-16H05042, KAKENHI-PROJECT-16J11714, KAKENHI-PROJECT-17H03669
[Journal Article] SFT-4/Surf4 control ER export of soluble cargo proteins and participate in ER exit site organization.2018
- Author(s)
  Saegusa K, Sato M, Morooka N, Hara T, Sato K
- Journal Title
  
  J Cell Biol.
  
  Volume: 印刷中 Issue: 6 Pages: 2073-2085
- DOI
  10.1083/jcb.201708115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19377, KAKENHI-PROJECT-16J11698, KAKENHI-PROJECT-17K08621
[Journal Article] Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons.2016
- Author(s)
  Yoshii SR, Kuma A, Akashi T, Hara T, Yamamoto A, Kurikawa Y, Itakura E, Tsukamoto S, Shitara H, Eishi Y, Mizushima N.
- Journal Title
  
  Developmental cell
  
  Volume: 39 Issue: 1 Pages: 116-130
- DOI
  10.1016/j.devcel.2016.09.001
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01194, KAKENHI-PROJECT-15H05637, KAKENHI-PROJECT-16H06167, KAKENHI-PROJECT-16K08613, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-15K19002
[Journal Article] Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells2016
- Author(s)
  Masataka Kunii, et al,
- Journal Title
  
  J. Cell Biol.
  
  Volume: 215 Issue: 1 Pages: 121-138
- DOI
  10.1083/jcb.201604030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-15H05953, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26242082, KAKENHI-PROJECT-15H04668, KAKENHI-PROJECT-26291036, KAKENHI-PROJECT-26350976, KAKENHI-PROJECT-26460290, KAKENHI-PROJECT-15K19525, KAKENHI-PROJECT-16K08519, KAKENHI-PROJECT-26460396
[Journal Article] REI-1 Is a Guanine Nucleotide Exchange Factor Regulating RAB-11 Localization and Function in C. elegans Embryos.2015
- Author(s)
  Sakaguchi A, Sato M, Sato K, Gengyo-Ando K, Yorimitsu T, Nakai J, Hara T, Sato K, Sato K.
- Journal Title
  
  Dev Cell
  
  Volume: 35(2) Issue: 2 Pages: 211-221
- DOI
  10.1016/j.devcel.2015.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19002, KAKENHI-PUBLICLY-26111503, KAKENHI-PROJECT-25870119, KAKENHI-PROJECT-26291036
[Journal Article] Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease.2014
- Author(s)
  Hara T, Hashimoto Y, Akuzawa T, Hirai R, Kobayashi H, Sato K.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1
- DOI
  10.1038/srep06992
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590341
[Journal Article] Caenorhabditis elegans chaperonin CCT/TRiC is required for actin and tubulin biogenesis and microvillus formation in intestinal epithelial cells2014
- Author(s)
  Keiko Saegusa, Miyuki Sato, Katsuya Sato, Junko Nakajima-Shimada, Akihiro Harada, and Ken Sato
- Journal Title
  
  Mol. Biol. Cell
  
  Volume: 25 Issue: 20 Pages: 3095-3104
- DOI
  10.1091/mbc.e13-09-0530
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23687027, KAKENHI-PROJECT-24390046, KAKENHI-PROJECT-24659084, KAKENHI-PUBLICLY-25113517, KAKENHI-PROJECT-26291036
[Journal Article] Fluorescence-based visualization of autophagic activity predicts mouse embryo viability2014
- Author(s)
  Satoshi Tsukamoto S, Hara T, Yamamoto A, Kito S, Minami N, Kubota T, Sato K, Kokubo T
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 4533-4533
- DOI
  10.1038/srep04533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23380164, KAKENHI-PUBLICLY-24116702, KAKENHI-PROJECT-24590341, KAKENHI-PLANNED-25111005
[Journal Article] Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking.2014
- Author(s)
  Yamasaki A, Hara T, Maejima I, Sato M, Sato K, Sato K.
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1
- DOI
  10.1038/srep05973
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590341
[Journal Article] FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.2008
- Author(s)
  Hara, T.
- Journal Title
  
  J. Cell Biol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023043
[Journal Article] 神経細胞内浄化機構としてのオートファジー2006
- Author(s)
  原太一他
- Journal Title
  
  細胞工学 25
  
  Pages: 644-645
- Data Source
  KAKENHI-PROJECT-17028056
[Journal Article] 神経細胞内浄化機構としてのオートファジー2006
- Author(s)
  原太一他
- Journal Title
  
  細胞工学 25
  
  Pages: 644-645
- Data Source
  KAKENHI-PROJECT-18023043
[Journal Article] Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice2006
- Author(s)
  Hara, T. et al.
- Journal Title
  
  Nature 441
  
  Pages: 885-889
- Data Source
  KAKENHI-PROJECT-18023043
[Journal Article] Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice2006
- Author(s)
  Hara, T. et al.
- Journal Title
  
  Nature 441
  
  Pages: 885-889
- Data Source
  KAKENHI-PROJECT-17028056
[Journal Article] Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.2006
- Author(s)
  Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N.
- Journal Title
  
  Nature. 15・441
  
  Pages: 819-820
- Data Source
  KAKENHI-PROJECT-17770175
[Journal Article] Intracellular quality control by autophagy : how does autophagy prevent neurodegeneration?2006
- Author(s)
  Mizushima N, Hara T.
- Journal Title
  
  Autophagy. 2・4
  
  Pages: 302-304
- Data Source
  KAKENHI-PROJECT-17770175
[Journal Article] Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle.2005
- Author(s)
  Hara T, Kamura T, Kotoshiba S, Tkahashi H, Fujiwara K, Onoyama I, Shirakawa M, Mizushima N, Nakayama KI.
- Journal Title
  
  Mol Cell Biol. 25・21
  
  Pages: 9292-9303
- Data Source
  KAKENHI-PROJECT-17770175
[Journal Article] Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase.2005
- Author(s)
  Kotoshiba S, Kamura T, Hara T, Ishida N, Nakayama KI.
- Journal Title
  
  J Biol Chem. 280・18
  
  Pages: 17694-17700
- Data Source
  KAKENHI-PROJECT-17770175
[Patent] マラリア予防治療薬2021
- Inventor(s)
  美田敏宏、久保原禅、菊地晴久、大島吉輝
- Industrial Property Rights Holder
  学校法人順天堂
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-055575
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K07139
[Patent] マラリア原虫の増殖抑制剤2019
- Inventor(s)
  美田敏宏、久保原禅、菊地晴久、大島吉輝
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-040682
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] Enhanced Metabolic Efficiency with Ketone Body Supplementation in Keto-Adaptation: Insights from Animal and Cell Culture Studies2024
- Author(s)
  Ma Sihui, Tong Yishan, Yano Satoshi, Suzuki Katsuhiko, Hara Taichi
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-20H00574
[Presentation] Pathological study of PSP-like syndrome cases with mutations in BSN and BSN knock-in mice2023
- Author(s)
  Hiroaki Yaguchi, Masahiro Wakita, Mika Otuski, Satoshi Tanikawa, Yasuo Miki, Akihiko Kudo, Azusa Nagai, Hisashi Uwatoko, Yasunori Mito, Kaichi Yoshizaki, Taichi Hara, Takeshi Ikeuchi, Shinya Tanaka, Koichi Wakabayashi, Ichiro Yabe
- Organizer
  日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K27511
[Presentation] 細胞性粘菌（Dictyostelium discoideum）柄細胞分化誘導因子を用いた新規誘導体の抗マラリア活性2023
- Author(s)
  吉田菜穂子、平井誠、菊地晴久、久保原禅、美田敏宏
- Organizer
  日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] フラボノイドにより誘導される新たなオートファジー制御機構の解明2023
- Author(s)
  塩田　皐希、Wang Jinyun、Xie Kun、矢野　敏史、原　太一
- Organizer
  第77回日本栄養・食料学会大会
- Data Source
  KAKENHI-PROJECT-20H00574
[Presentation] 皮膚の抗老化と UV 障害保護に関するイワヒバの機能性評価2022
- Author(s)
  塩田皐希, 関根結夏子, 矢野敏史, 原太一
- Organizer
  日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] オートファジー制御における細胞性粘菌由来の生物活性物質DIFの機能解析2022
- Author(s)
  山田龍、矢野敏史、山越正汰、菊地晴久、久保原禅、原太一
- Organizer
  日本農芸化学会 2022年度京都大会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] 細胞性粘菌由来の生物活性物質DIF-1とその誘導体によるタンパク質代謝制御機構の解析2022
- Author(s)
  山田龍, 矢野敏史, 山越正汰, 菊地晴久, 久保原禅, 原太一
- Organizer
  日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] スペルミンとスペルミジンバランスによるオートファジー制御機構の解析と機能性食品の開発2022
- Author(s)
  Xie Kun, 矢野敏史, 山越正汰, 太田智絵, 宇都拓洋, 坂井麻衣子, 大西康太, 久保田拓海, 原太一
- Organizer
  日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] 4,4’-ジメトキシカルコンによる mTORC1 非依存的な食成分依存性オートファジーの分子機構の解明2022
- Author(s)
  ワンジンユン, シャクン, 原太一
- Organizer
  第27回日本フードファクター学会　学術集会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] 細胞性粘菌由来の生物活性物質DIF-1とその誘導体によるタンパク質代謝制御機構の解析2022
- Author(s)
  山田龍，矢野敏史，山越正汰，菊地晴久，久保原禅，原太一
- Organizer
  日本栄養食糧学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] DIF-1 promotes glucose uptake in mouse C2C12 myotube cells2022
- Author(s)
  Fukunaga Y, Nakanishi K, Sugita H, Kubohara Y.
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] 明日葉カルコンによるオートファジー制御機構の解析2022
- Author(s)
  王縉雲, Xie Kun, 矢野敏史, 原太一
- Organizer
  日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] 筋分化で誘導されるタンパク質ZSWIM8はC2C12筋芽細胞の分化を抑制する2022
- Author(s)
  奥村文彦、大木のどか、藤木結葉、生田李緒、濱田俊、中務邦雄、久本直毅、原太一、嘉村巧
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] イワヒバの美容効果に関する機能性評価2022
- Author(s)
  塩田皐希、関根結夏子、矢野敏史、原太一
- Organizer
  日本農芸化学会 2022年度京都大会
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] BSN遺伝子変異例におけるタンパク質品質管理の病理学的検討とモデルマウス作製2022
- Author(s)
  矢口裕章，脇田雅大, 長井　梓，白井慎一,岩田育子,松島理明,三木康生，原　太一，吉崎嘉一，高橋秀尚，若林　孝一,矢部一郎
- Organizer
  第63回神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20H03585
[Presentation] DIF誘導体が熱帯熱マラリア原虫の増殖を阻害する2022
- Author(s)
  美田敏弘、平井誠、吉田菜穂子、菊地晴久、久保原禅
- Organizer
  日本細胞性粘菌学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] D アミノ酸によるタンパク質代謝制御機構の解明2021
- Author(s)
  Wang Jinyun、山越正汰、Xie Kun、矢野敏史、原太一
- Organizer
  第 26 回日本フードファクター学会学術集会　JSoFF2021
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] Cul2結合タンパク質ZSWIM8はC2C12筋芽細胞の分化を抑制する2021
- Author(s)
  奥村文彦、大木のどか、藤木結葉、生田李緒、濱田俊、中務邦雄、久本直毅、原太一、嘉村巧
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 毛乳頭細胞の増殖と育毛関連遺伝子発現に対する海老名イチゴの機能性2021
- Author(s)
  謝凉晶、Wang Jinyun、廣川隆彦、宮内勇樹、原園枝、矢野敏史、原太一
- Organizer
  第 26 回日本フードファクター学会学術集会　JSoFF2021
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] Cul2結合タンパク質ZSWIM8はC2C12筋芽細胞分化に伴い発現誘導される2021
- Author(s)
  奥村文彦、大木のどか、藤木結葉、生田李緒、濱田俊、中務邦雄、久本直毅、原太一、嘉村巧
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] アルコール性肝傷害における電解水素水による軽減作用のメカニズム解析2021
- Author(s)
  矢野敏史、Wang Jinyun、樺山繁、原太一
- Organizer
  第 26 回日本フードファクター学会学術集会　JSoFF2021
- Data Source
  KAKENHI-PROJECT-20H03408
[Presentation] DIF-1による糖代謝促進作用とAMP kinase2020
- Author(s)
  久保原禅，本間好，大島吉輝，菊地晴久
- Organizer
  日本細胞性粘菌学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] ハロゲン置換した DIF 誘導体の抗腫瘍作用2019
- Author(s)
  久保原禅, 戸塚響子, 牧岡優佳, 飯泉恭一, 大島吉輝, 菊地晴久
- Organizer
  日本細胞性粘菌学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] 出芽酵母転写抑制因子Mtt24の分解制御機構2019
- Author(s)
  森田敏基、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] オートファジーの健康評価と未病制御への応用2019
- Author(s)
  原太一
- Organizer
  日本細胞性粘菌学会第9回例会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08621
[Presentation] アダプタータンパク質 Mmr1の選択的分解によるミトコンドリアの局在制御機構2019
- Author(s)
  吉川拓、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 飢餓状態におけるRrn3の分解制御機構の解析2019
- Author(s)
  酒井洋二、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] DIF誘導体の有する抗菌活性2019
- Author(s)
  久保原禅, 白土佳子, 石垣宏尚, 高橋克典, 大島吉輝, 菊地晴久
- Organizer
  日本細胞性粘菌学会
- Data Source
  KAKENHI-PROJECT-19K07139
[Presentation] 出芽酵母のストレス応答因子 Wta1の制御機構の解析2019
- Author(s)
  渡邉祥太郎、小原圭介、奥村文彦、嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] Application of autophagy to the health promotion2019
- Author(s)
  Taichi Hara
- Organizer
  ICoFF2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08621
[Presentation] ユビキチンリガーゼSPSB4はEphB2を介した細胞間反発運動を抑制する2018
- Author(s)
  奥村文彦、奥村（城尾）晶子、小原圭介、Alexander Petersen、錦見昭彦、福井宣規、中務邦雄、嘉村巧
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06213
[Presentation] 初期ゴルジ品質管理システムによるγ-セクレターゼ複合体形成制御メカニズムの解明2017
- Author(s)
  原太一
- Organizer
  日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-17K08621
[Presentation] 線虫 C. elegans をモデルとして用いたリポタンパク質の生合成および分泌機構の解析2016
- Author(s)
  三枝慶子、佐藤美由紀、坂口愛沙、原太一、佐藤健
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] Functional analysis of a cargo receptor homolog SFT-4 in C. elegans2016
- Author(s)
  三枝慶子、佐藤美由紀、坂口愛沙、原太一、佐藤健
- Organizer
  N-Hybrid conference 2016
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター（新潟県新潟市）
- Year and Date
  2016-01-30
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease2016
- Author(s)
  Taichi Hara, Yukiko Hashimoto, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, and Ken Sato
- Organizer
  The 2nd IMCR Symposium on Endocrine and Metabolism:International Frontiers in Homeostatic Regulation Research
- Place of Presentation
  群馬大学刀城会館（群馬県前橋市）
- Year and Date
  2016-11-10
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 受精前後における細胞内膜系リモデリングの時空間的制御機構2015
- Author(s)
  坂口愛沙，佐藤美由紀，安藤恵子，佐藤克哉，中井淳一，前島郁子，原太一，依光朋宏，佐藤健，佐藤健
- Organizer
  第３８回日本分子生物学会，大８８回日本生化学会　合同大会
- Place of Presentation
  兵庫県,神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 線虫 C.elegans における積み荷受容体ホモログSFT-4 の機能解析2015
- Author(s)
  三枝慶子，佐藤美由紀，坂口愛沙，原太一，佐藤健
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  兵庫県,神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 線虫 C.elegans における積み荷受容体ホモログ SFT-4 の機能解2015
- Author(s)
  三枝慶子、佐藤美由紀、坂口愛沙、原太一、佐藤健
- Organizer
  第1回細胞生物若手の会シンポジウム
- Place of Presentation
  タワーホール船堀（東京都江東区）
- Year and Date
  2015-06-29
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 受精前後のマウス卵細胞質における脂肪滴の動態観察2015
- Author(s)
  塚本智史、原太一、南直治郎、佐藤健
- Organizer
  第108回日本繁殖生物学会大会
- Place of Presentation
  宮崎県，宮崎大学
- Year and Date
  2015-09-19
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 疾患関連変異膜タンパク質の小胞体局在化における初期ゴルジ品質管理機構の役割2015
- Author(s)
  原太一、橋本由紀子、阿久澤共子、平井里香、小林久江、佐藤健
- Organizer
  第１０回臨床ストレス応答学会大会
- Place of Presentation
  東京農工大学（東京都小金井市）
- Year and Date
  2015-11-06
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 線虫 C.elegans における積み荷受容体ホモログ SFT-4 の機能解2015
- Author(s)
  三枝慶子、佐藤美由紀、坂口愛沙、原太一、佐藤健
- Organizer
  第６７回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江東区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] In vivo analysis of processing bodies using transgenic mice expressing GFP-Dcp1a2015
- Author(s)
  Satoshi Tsukamoto, Taichi Hara, Ken Sato, Naojiro Minami Seiji Kito, Toshiaki Kokubo
- Organizer
  15th International Congress of Radiation Research (ICRR2015)
- Place of Presentation
  京都府，京都国際会議場
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 受精前後のマウス卵細胞質における脂肪滴の動態観察2015
- Author(s)
  塚本智史、原太一、南直治郎、佐藤健
- Organizer
  第108回日本繁殖生物学会大会
- Place of Presentation
  宮崎大学（宮崎県宮崎市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] Functional analysis of a cargo receptor homolog SFT-4 in C. elegans2015
- Author(s)
  Keiko Saegusa, Miyuki Sato, Aisa Sakaguchi, Taichi Hara, Ken Sato.
- Organizer
  第14回群馬大学大学院医学系研究科・大学院生によるワークショップ
- Place of Presentation
  群馬大学医学部（群馬県前橋市）
- Year and Date
  2015-09-09
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease2015
- Author(s)
  Taichi Hara, Yukiko Hashimoto, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, and Ken Sato
- Organizer
  第38回日本神経科学大会, Neuroscience2015
- Place of Presentation
  神戸国際会議場、神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 線虫 C.elegans における積み荷受容体ホモログ SFT-4 の機能解2015
- Author(s)
  三枝慶子、佐藤美由紀、坂口愛沙、原太一、佐藤健
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 疾患原因膜タンパク質が小胞体に蓄積する分子メカニズム2015
- Author(s)
  佐藤健、山崎章徳、前島郁子、原太一
- Organizer
  第６７回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江東区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] Rer1とカルネキシンはCharcot-Marie-Tooth（CMT）病の発症と関連する変異PMP22の小胞体蓄積を制御する2015
- Author(s)
  原太一、橋本由紀子、阿久澤共子、平井里香、小林久江、佐藤健
- Organizer
  第６７回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀（東京都江東区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] In vivo analysis of processing bodies using transgenic mice expressing GFP-Dcp1a2015
- Author(s)
  Satoshi Tsukamoto, Taichi Hara, Ken Sato, Naojiro Minami Seiji Kito, Toshiaki Kokubo
- Organizer
  15th International Congress of Radiation Research (ICRR2015)
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] GFP-Dcp1aトランスジェニックマウスを用いた生体内のProcessing bodiesの可視化2015
- Author(s)
  塚本智史、伊林恵美、和田彩子、鬼頭靖司、小久保年章、原太一、佐藤健、南直治郎
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 疾患関連変異膜タンパク質の小胞体局在化における初期ゴルジ品質管理機構の役割2015
- Author(s)
  原太一、橋本由紀子、阿久澤共子、平井里香、小林久江、佐藤健
- Organizer
  第38回日本分子生物学会，第88回日本生化学会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] GFP-Dcp1aトランスジェニックマウスを用いた生体内のProcessing bodiesの可視化2015
- Author(s)
  塚本智史、伊林恵美、和田彩子、鬼頭靖司、小久保年章、原太一、佐藤健、南直治郎
- Organizer
  第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
- Place of Presentation
  兵庫県,神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] Rer1 and calnexin regulate endoplasmic reticulum retention of a peripheral myelin protein 22 mutant that causes type 1A Charcot-Marie-Tooth disease2015
- Author(s)
  Taichi Hara, Yukiko Hashimoto, Tomoko Akuzawa, Rika Hirai, Hisae Kobayashi, and Ken Sato
- Organizer
  第58回日本神経化学会大会
- Place of Presentation
  大宮ソニックシティ（埼玉県さいたま市）
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] 線虫 C.elegans における積み荷受容体ホモログ SFT-4 の機能解析2015
- Author(s)
  三枝慶子，佐藤美由紀，坂口愛沙，原太一，佐藤健
- Organizer
  第６７回日本細胞生物学会大会
- Place of Presentation
  東京都，タワーホール船堀
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 受精前後における細胞内膜系リモデリングの時空間的制御機構2015
- Author(s)
  坂口愛沙、佐藤美由紀、安藤恵子、佐藤克哉、中井淳一、前島郁子、原太一、依光朋宏、佐藤健、佐藤健
- Organizer
  第38回日本分子生物学会，第88回日本生化学会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19002
[Presentation] ミスフォールドタンパク質の小胞体蓄積を病因とする遺伝病の治療応用を目指した機能性化合物の探索2014
- Author(s)
  原　太一，佐藤　健
- Organizer
  日本フードファクター学会
- Place of Presentation
  鹿児島県鹿児島市鹿児島大学
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] C. elegans chaperonin CCT/TRiC is required for actin biogenesis and microvillus formation in intestinal epithelial cells2014
- Author(s)
  Keiko Saegusa, Miyuki Sato, Katsuya Sato, Taichi Hara, Akihiro Harada, and Ken Sato.
- Organizer
  The C. elegans Development, Cell Biology, and Gene Expression Topic Meeting in association with the 6th Asia-Pacific C. elegans Meeting
- Place of Presentation
  奈良県奈良市奈良県新公会堂
- Year and Date
  2014-07-16
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 細胞内メンブレントラフィックによるマウス初期胚の発生・分化制御機構の解析2014
- Author(s)
  原　太一
- Organizer
  第119回日本解剖学会総会・全国学術集会
- Place of Presentation
  自治医科大学キャンパス（栃木県下野市）
- Data Source
  KAKENHI-PROJECT-24590341
[Presentation] 細胞内メンブレントラフィックによるマウス初期胚の発生・分化制御機構の解析2014
- Author(s)
  原　太一
- Organizer
  第119回日本解剖学会総会・全国学術集会
- Place of Presentation
  自治医科大学キャンパス（栃木県下野市）
- Data Source
  KAKENHI-PUBLICLY-24116702
[Presentation] 神経疾患発症における初期ゴルジ品質管理機構の役割2014
- Author(s)
  原　太一，佐藤　健
- Organizer
  第11回群馬大学生体調節研究所・名古屋大学環境医学研究所　合同シンポジウム
- Place of Presentation
  愛知県名古屋市名古屋大学
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 分子選別装置Rer1による膜タンパク質の複合体形成調節の生理的役割2014
- Author(s)
  原太一，山本正道，堀居拓郎，角田美佳，小林久江，塚本智史，神吉康晴，井上剛，金木清美，畑田出穂，佐藤健
- Organizer
  第66回　日本細胞生物学会年会
- Place of Presentation
  奈良県奈良市奈良県新公会堂
- Year and Date
  2014-06-12
- Data Source
  KAKENHI-PROJECT-26291036
[Presentation] 哺乳動物における分子選別装置Rer1の生理的役割2013
- Author(s)
  原太一，角田美佳，山本正道，堀居拓郎，塚本智史，畑田出穂，佐藤健
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインク愛知（愛知県産業労働センター）愛知県名古屋市
- Data Source
  KAKENHI-PUBLICLY-24116702
[Presentation] マウス初期胚発生過程における分子選別装置Rer1の生理的役割2013
- Author(s)
  原太一，山本正道，堀居拓郎，角田美佳，塚本智史，神吉康晴，井上剛，金木清美，畑田出穂，佐藤健
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-24590341
[Presentation] Physiological roles of a sorting receptor Rer1p during early embryogenesis in mice2013
- Author(s)
  Taichi Hara, Masamichi Yamamoto, Mika Tsunoda, Satoshi Tsukamoto and Ken Sato
- Organizer
  第61回NIBBコンファレンス　Cellular community in mammalian embryogenesis
- Place of Presentation
  自然科学研究機構　岡崎カンファレンスセンター　（愛知県岡崎市）
- Data Source
  KAKENHI-PUBLICLY-24116702
[Presentation] Physiological roles of a sorting receptor Rer1p during early embryogenesis in mice2013
- Author(s)
  Taichi Hara, Masamichi Yamamoto, Mika Tsunoda, Satoshi Tsukamoto and Ken Sato
- Organizer
  第61回NIBBコンファレンス　Cellular community in mammalian embryogenesis
- Place of Presentation
  自然科学研究機構　岡崎カンファレンスセンター
- Data Source
  KAKENHI-PROJECT-24590341
[Presentation] マウス初期胚発生過程における分子選別装置Rer1の生理的役割2013
- Author(s)
  原太一，山本正道，堀居拓郎，角田美佳，塚本智史，神吉康晴，井上剛，金木清美，畑田出穂，佐藤健
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Data Source
  KAKENHI-PUBLICLY-24116702
[Presentation] 哺乳動物における分子選別装置Rer1の生理的役割2013
- Author(s)
  原太一，角田美佳，山本正道，堀居拓郎，塚本智史，畑田出穂，佐藤健
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインク愛知（愛知県産業労働センター）愛知県名古屋市
- Data Source
  KAKENHI-PROJECT-24590341
[Presentation] Analysis of novel physiological roles of membrane trafficking in animal models2012
- Author(s)
  Taichi Hara
- Organizer
  第85回日本生化学大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-24116702
[Presentation] Analysis of novel physiological roles of membrane trafficking in animal models2012
- Author(s)
  Taichi Hara
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590341
[Presentation] 分子選別装置Rer1による膜タンパク質の複合体形成調節の生理的役割
- Author(s)
  原太一，山本正道，堀居拓郎，角田美佳，小林久江，塚本智史，神吉康晴，井上剛，金木清美，畑田出穂，佐藤健
- Organizer
  第66回　日本細胞生物学会年会
- Place of Presentation
  奈良県新公会堂・東大寺総合文化センター（奈良県・奈良市）
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24590341
[Presentation] ミスフォールドタンパク質の小胞体蓄積を病因とする遺伝病の治療応用を目指した機能性化合物の探索
- Author(s)
  原　太一，佐藤　健
- Organizer
  第19回　日本フードファクター学会
- Place of Presentation
  鹿児島大学（鹿児島県・鹿児島市）
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-24590341

1. Kubohara Yuzuru (00221937)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. Yabe Ichiro (60372273)

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3. 水島昇 (10353434)

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6. 池内健 (20372469)

# of Collaborated Projects: 2 results

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7. 高橋秀尚 (30423544)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. 若林孝一 (50240768)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. Sato Ken (30311343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
10. Okumura Fumihiko (00507212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
11. Suzuki Katsuhiko (80344597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 川西範明 (00706533)

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13. 稲田全規 (80401454)

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14. 吉崎嘉一 (50393161)

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18. 福永優子 (80254522)

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19. 向井悟 (90467887)

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20. 丸亀裕貴 (31002454)

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21. 矢野敏史 (60936615)

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22. XIE KUN

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23. HOU De-xing

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24. TSUKAMOTO Satoshi

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25. Saegusa Keiko

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# of Collaborated Products: 1 results
26. 板倉英祐

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# of Collaborated Products: 2 results
27. 坂尾こず枝

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# of Collaborated Products: 1 results
28. 美田敏宏

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29. 平井誠

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30. 佐藤美由紀

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31. 前島郁子

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32. 南直治郎

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33. 千葉朋希

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34. 中務邦雄

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35. 大南博和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 大西康太

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 増田真志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hara Taichi 原 太一

HARA Taichi 原 太一

原 太一 ハラ タイチ

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細胞内液滴を基盤としたポリフェノールによる統合的ストレス制御メカニズムの解明Principal Investigator

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D-アミノ酸によるオートファジー誘導機構の解明と健康制御への応用Principal Investigator

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Development of innovative treatments for rare and intractable diseases based on natural pharmaceutical resourcesPrincipal Investigator

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Molecular pathogenesis of neurological diseases caused by disruption of early Golgi quality control systemPrincipal Investigator

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Physiological role and molecular mechanism of early Golgi quality control systemPrincipal Investigator

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初期胚発生と連動した細胞膜タンパク質の分解制御機構と生理的役割の解明Principal Investigator

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Hara Taichi 原太一

HARA Taichi 原太一

原太一ハラタイチ

[Book] 人間科学で読み解く幸せな認知症　認知症の人は「恍惚の人」ではない2022

[Book] 神経変性疾患におけるオートファジーの役割「神経変性疾患のサイエンス」高橋良輔編2007

[Book] 蛋白質核酸酵素2006