NAKAYAMA Takayuki 中山享之

… Alternative Names

中山享之ナカヤマタカユキ

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Researcher Number	00456659
Other IDs
Affiliation (Current)	2025: 愛知医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 愛知医科大学, 医学部, 教授 2017 – 2023: 愛知医科大学, 医学部, 教授 2015 – 2016: 愛知医科大学, 医学部, 准教授 2012 – 2014: 愛知医科大学, 医学部, 講師 2011: 名古屋大学, 医学(系)研究科(研究院), 特任講師 2008 – 2010: Nagoya University, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 53030:Respiratory medicine-related / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 骨髄造血微小環境 / 骨芽細胞 / 血管新生 / ケモカイン / メタボローム解析 / 間葉系幹細胞 / 脂肪細胞分化 / ノックダウン / shRNA / Ebf3 … More / 造血支持能力 / 脂肪組織由来間葉系幹細胞 / 血液凝固 / 白血病幹細胞ニッチ / 多能性幹細胞 / がん微小環境 / 体性幹細胞 / 白血病ニッチェ / 腫瘍微小環境 / 血液学 / ニッチェ / 血液悪性腫瘍幹細胞 / 血液腫瘍学 / 細胞療法 / 再生医学 / 造血微小環境 / 脂肪由来間葉系幹細胞 … More Except Principal Investigator 慢性閉塞性肺疾患 / 間葉系幹細胞 / COPD / 肺気腫 / CCL2 / 尿毒素 / 動脈硬化 / 動脈石灰化 / インフラマソーム / 尿毒症性心筋症 / Notchシグナル / インドキシル硫酸 Less

慢性DICの病態解明と適切な治療法開発：XIII因子とDOACに着目してPrincipal Investigator
- Principal Investigator
  
  中山享之
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
ケモカイン抑制能を強化した新規間葉系幹細胞による慢性閉塞性肺疾患の細胞療法開発
- Principal Investigator
  
  宮原信明
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Okayama University
Analysis of metabolic pathways in adipose tissue-derived mesenchymal stem cells-hematopoietic stem cells: focus on anti-aging effectsPrincipal Investigator
- Principal Investigator
  
  Nakayama Takayuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Aichi Medical University
Pathophysiology of vascular injury via Notch signaling and metabolic reprogramming by urea toxins.
- Principal Investigator
  
  Takeshita Kyosuke
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Saitama Medical University
analysis of the regulatory mechanism for the vascular niche to protect leukemia stem cells.Principal Investigator
- Principal Investigator
  
  Nakayama Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Aichi Medical University
Analysis of the functions of MUSE in the lymphoma microenvironment.Principal Investigator
- Principal Investigator
  
  Nakayama Takayuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Aichi Medical University
Effects of FGF2 on the leukemia microenvironment in the bone marrowPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Takayuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Aichi Medical University
  Nagoya University
Cell therapy using adipose tissue-derived mesenchymal stem cells for primary myelofibrosisPrincipal Investigator
- Principal Investigator
  
  NAKAYAMA Takayuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Nagoya University

[Journal Article] Serum Produced from Expired Fresh Frozen Plasma and Cryosupernatant Supports the Proliferation of Human Cells: Cost-Effective Alternatives to Fetal Bovine Serum2023
- Author(s)
  Kazuki Ishiyama, Mika Ogawa, Hidefumi Kato, Kyosuke Takeshita, Ryuzo Ueda, Takayuki Nakayama
- Journal Title
  
  J Blood Disord Transfus
  
  Volume: 14 Pages: 1-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08721
[Journal Article] Indoxyl Sulfate Activates NLRP3 Inflammasome to Induce Cardiac Contractile Dysfunction Accompanied by Myocardial Fibrosis and Hypertrophy2022
- Author(s)
  Yamaguchi Kazutoshi、Yisireyili Maimaiti、Goto Sumie、Cheng Xian Wu、Nakayama Takayuki、Matsushita Tadashi、Niwa Toshimitsu、Murohara Toyoaki、Takeshita Kyosuke
- Journal Title
  
  Cardiovascular Toxicology
  
  Volume: 22 Issue: 4 Pages: 365-377
- DOI
  10.1007/s12012-021-09718-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02729, KAKENHI-PROJECT-20K08711
[Journal Article] Pretreatment Immature Platelet Fraction as a Surrogate of Reticulated Platelets Predicts the Response to Corticosteroids in Adults with Immune Thrombocytopenia2021
- Author(s)
  Takami Akiyoshi、Mizuno Shohei、Nakamura Ayano、Kanasugi Jo、Yamamoto Hidesuke、Vu?Quang Lam、Nakagami Yuya、Nakano Yuta、Yamada Saki、Matsumura Saori、Takasugi Souichi、Uchino Kaori、Horio Tomohiro、Murakami Satsuki、Oohigashi Yuka、Nakayama Takayuki、Tani Hiroya、Enomoto Megumi、Hanamura Ichiro
- Journal Title
  
  Acta Haematologica
  
  Volume: 144 Issue: 3 Pages: 345-349
- DOI
  10.1159/000510460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-20K08721, KAKENHI-PROJECT-21K08427
[Journal Article] Point‐of‐care nerve conduction device predicts the severity of diabetic polyneuropathy: A quantitative, but easy‐to‐use, prediction model2021
- Author(s)
  Kamiya Hideki、Shibata Yuka、Himeno Tatsuhito、Tani Hiroya、Nakayama Takayuki、Murotani Kenta、Hirai Nobuhiro、Kawai Miyuka、Asada‐Yamada Yuriko、Asano‐Hayami Emi、Nakai‐Shimoda Hiromi、Yamada Yuichiro、Ishikawa Takahiro、Morishita Yoshiaki、Kondo Masaki、Tsunekawa Shin、Kato Yoshiro、Baba Masayuki、Nakamura Jiro
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 4 Pages: 583-591
- DOI
  10.1111/jdi.13386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08721
[Journal Article] Alterations of retinal thickness measured by optical coherence tomography correlate with neurophysiological measures in diabetic polyneuropathy2021
- Author(s)
  Yamada Y.、Himeno T.、Tsuboi K.、Shibata Y.、Kawai M.、Asada‐Yamada Y.、Hayashi Y.、Asano‐Hayami E.、Hayami T.、Ishida Y.、Ejima Y.、Motegi M.、Asano S.、Kato M.、Nagao E.、Nakai‐Shimoda H.、Ishikawa T.、Morishita Y.i、Kondo M.、Tsunekawa S.、Kato Y.、Nakayama T.、Kamei M.、Nakamura J.、Kamiya H.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 8 Pages: 1430-1441
- DOI
  10.1111/jdi.13476
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08721
[Journal Article] Notch1 haploinsufficiency in mice accelerates adipogenesis2021
- Author(s)
  Yamaguchi Kazutoshi、Hayashi Motoharu、Uchida Yasuhiro、Cheng Xian Wu、Nakayama Takayuki、Matsushita Tadashi、Murohara Toyoaki、Takeshita Kyosuke
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 16761-16761
- DOI
  10.1038/s41598-021-96017-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02729, KAKENHI-PROJECT-20K08711
[Journal Article] In vivo tracking of transplanted macrophages with near infrared fluorescent dye reveals temporal distribution and specific homing in the liver that can be perturbed by clodronate liposomes2020
- Author(s)
  Nishiwaki Satoshi、Saito Shigeki、Takeshita Kyosuke、Kato Hidefumi、Ueda Ryuzo、Takami Akiyoshi、Naoe Tomoki、Ogawa Mika、Nakayama Takayuki
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 12 Pages: e0242488-e0242488
- DOI
  10.1371/journal.pone.0242488
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-18H02729
[Journal Article] Indoxyl Sulfate-induced Vascular Calcification is mediated through Altered Notch Signaling Pathway in Vascular Smooth Muscle Cells2020
- Author(s)
  Yamaguchi Kazutoshi、Yisireyili Maimaiti、Goto Sumie、Kato Katsuhiro、Cheng Xian Wu、Nakayama Takayuki、Matsushita Tadashi、Niwa Toshimitsu、Murohara Toyoaki、Takeshita Kyosuke
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 17 Issue: 17 Pages: 2703-2717
- DOI
  10.7150/ijms.43184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08711, KAKENHI-PROJECT-18H02729
[Journal Article] Mesenchymal stem/stromal cells stably transduced with an inhibitor of CC chemokine ligand 2 ameliorate bronchopulmonary dysplasia and pulmonary hypertension2020
- Author(s)
  Suzuki Toshihiko、Sato Yoshiaki、Yamamoto Hidenori、Kato Taichi、Kitase Yuma、Ueda Kazuto、Mimatsu Haruka、Sugiyama Yuichiro、Onoda Atsuto、Saito Shigeki、Takahashi Yoshiyuki、Nakayama Takayuki、Hayakawa Masahiro
- Journal Title
  
  Cytotherapy
  
  Volume: - Issue: 4 Pages: 180-192
- DOI
  10.1016/j.jcyt.2020.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17357, KAKENHI-PROJECT-18J01110, KAKENHI-PROJECT-17K09944, KAKENHI-PROJECT-18K15667, KAKENHI-PROJECT-19K08341, KAKENHI-PROJECT-19K17324
[Journal Article] Validity and reliability of a point-of-care nerve conduction device in diabetes patients2019
- Author(s)
  Shibata Yuka、Himeno Tatsuhito、Kamiya Taeko、Tani Hiroya、Nakayama Takayuki、Kojima Chika、Sugiura-Roth Yukako、Naito Ena、Kondo Masaki、Tsunekawa Shin、Kato Yoshiro、Nakamura Jiro、Kamiya Hideki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 印刷中 Issue: 5 Pages: 1291-1298
- DOI
  10.1111/jdi.13007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09944
[Journal Article] Immunomodulatory and Metabolic Changes after Gnetin-C Supplementation in Humans.2019
- Author(s)
  Nakagami Y, Suzuki S, Espinoza JL, Vu Quang L, Enomoto M, Takasugi S, Nakamura A, Nakayama T, Tani H, Hanamura I, Takami A
- Journal Title
  
  Nutrients
  
  Volume: 11 Issue: 6 Pages: 1403-1403
- DOI
  10.3390/nu11061403
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07277, KAKENHI-PROJECT-18K08343, KAKENHI-PROJECT-17K09944
[Journal Article] Reduction in adverse transfusion reactions with increased use of washed platelet concentrates in Japan?A retrospective multicenter study2019
- Author(s)
  Ikebe Emi、Matsuoka Sahoko、Tanaka Asashi、Yonemura Yuji、Fujii Yasuhiko、Ohsaka Akimichi、Okazaki Hitoshi、Kitazawa Junichi、Ohtani Shinichi、Nakayama Takayuki、Momose Shun-ya、Miwa Izumi、Taira Rikizo、Toyota Kuro、Kino Shuichi、Kato Hidefumi、Hamaguchi Isao
- Journal Title
  
  Transfusion and Apheresis Science
  
  Volume: 58 Issue: 2 Pages: 162-168
- DOI
  10.1016/j.transci.2018.12.021
- Data Source
  KAKENHI-PROJECT-17K09944
[Journal Article] Angiotensin receptor blocker irbesartan reduces stress-induced intestinal inflammation via AT1a signaling and ACE2-dependent mechanism in mice2018
- Author(s)
  Yisireyili Maimaiti、Uchida Yasuhiro、Yamamoto Koji、Nakayama Takayuki、Cheng Xian Wu、Matsushita Tadashi、Nakamura Shigeo、Murohara Toyoaki、Takeshita Kyosuke
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 69 Pages: 167-179
- DOI
  10.1016/j.bbi.2017.11.010
- NAID
  120006517674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09944
[Journal Article] Identification of a novel missense mutation (563G>a) in the ABO gene associated with a Bel phenotype.2016
- Author(s)
  Niwa R, Nakayama T, Ishii H, Fujita E, Ishiyama K, Matsuo T, Shimizu A, Gao S, Hayashi M, Katai A, Ando T, Takahashi M, Takeshita K, Takami A, Kato H.
- Journal Title
  
  Transfusion
  
  Volume: 未定 Issue: 5 Pages: 1242-3
- DOI
  10.1111/trf.13507
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461435, KAKENHI-PROJECT-25461336, KAKENHI-PROJECT-15K09513
[Journal Article] Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions.2016
- Author(s)
  Sugimoto K, Miyata Y, Nakayama T, Saito S, Suzuki R, Hayakawa F, Nishiwaki S, Mizuno H, Takeshita K, Kato H, Ueda R, Takami A, Naoe T
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 30779-30781
- DOI
  10.1038/srep30779
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461435, KAKENHI-PROJECT-15K09513
[Journal Article] A retrospective observational study to assess adverse transfusion reactions of patients with and without prior transfusion history2015
- Author(s)
  Kato H, Nakayama T, Uruma M, Okuyama Y, Handa M, Tomiyama Y, Shimodaira S and Takamoto S
- Journal Title
  
  VoxSanguinis
  
  Volume: 108(3) Issue: 3 Pages: 243-50
- DOI
  10.1111/vox.12208
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461435
[Journal Article] Repeated exposure rather than the total volume of transfused components may influence the incidence of allergic transfusion reactions.2015
- Author(s)
  Kato H, Nakayama T, Uruma M, Okuyama Y, Handa M, Tomiyama Y, Shimodaira S, Takamoto S.
- Journal Title
  
  Transfusion
  
  Volume: 55 Issue: 11 Pages: 2576-2581
- DOI
  10.1111/trf.13201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461435
[Journal Article] Recovery of flow-mediated vasodilatation after repetitive measurements is involved in early vascular impairment: comparison with indices of vascular tone.2014
- Author(s)
  Inaba H, Takeshita K, Uchida Y, Hayashi M, Okumura T, Hirashiki A, Yoshikawa D, Ishii H, Yamamoto K, Nakayama T, Hirayama M, Matsumoto H, Matsushita T, Murohara T
- Journal Title
  
  PLOS one
  
  Volume: 9(1) Issue: 1 Pages: 1-9
- DOI
  10.1371/journal.pone.0083977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-24500458, KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25461336, KAKENHI-PROJECT-26461435
[Journal Article] Angiotensin II receptor blocker ameliorates stress-induced adipose tissue inflammation and insulin resistance.2014
- Author(s)
  Hayashi M, Takeshita K, Uchida Y, Yamamoto K, Kikuchi R, Nakayama T, Nomura E, Cheng XW, Matsushita T, Nakamura S, Murohara T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: e116163-e116163
- DOI
  10.1371/journal.pone.0116163
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591421, KAKENHI-PROJECT-25461336, KAKENHI-PROJECT-25461445, KAKENHI-PROJECT-26461435, KAKENHI-PROJECT-26860367
[Journal Article] Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions2014
- Author(s)
  Satoshi Nishiwaki, Takayuki Nakayama, Makoto Murata, Tetsuya Nishida, Seitaro Terakura, Shigeki Saito, Tomonori Kato, Hiroki Mizuno, Nobuhiko Imahashi, Aika Seto, Yukiyasu Ozawa, Koichi Miyamura, Masafumi Ito, Kyosuke Takeshita, Hidefumi Kato, Shinya Toyokuni, Keisuke Nagao, Ryuzo Ueda, and Tomoki Naoe
- Journal Title
  
  PLOS one
  
  Volume: 9(5) Issue: 5 Pages: e96252-e96252
- DOI
  10.1371/journal.pone.0096252
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591382, KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24790969, KAKENHI-PROJECT-26461435
[Journal Article] Cell therapy using adipose-derived mesenchymal stromal cells : current status and perspectives2013
- Author(s)
  Nakayama T, and Kato H
- Journal Title
  
  Japanese Journal of Transfusion and Cell Therapy
  
  Volume: 59(3) Pages: 450-456
- NAID
  10031185432
- URL
  https://www.jstage.jst.go.jp/article/jjtc/59/3/59_450/_article/-char/ja/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591382
[Journal Article] Stress Augments Insulin Resistance and Prothrombotic State : Role of Visceral Adipose-Derived Monocyte Chemoattractant Protein-12012
- Author(s)
  Uchida Y
- Journal Title
  
  Diabetes
  
  Volume: (In press) Issue: 6 Pages: 1552-61
- DOI
  10.2337/db11-0828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-24591421
[Journal Article] Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomib2012
- Author(s)
  水野　紘樹
- Journal Title
  
  Leukemia
  
  Volume: 26 Issue: 10 Pages: 2269-2269
- DOI
  10.1038/leu.2012.81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790907, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-23659487
[Journal Article] Dexamethasone palmitate successfully attenuates hemophagocytic syndrome after allogeneic stem cell transplantation : macrophage-targeted steroid therapy2012
- Author(s)
  西脇聡史
- Journal Title
  
  International Journal of Hematology
  
  Volume: (Epub ahead of print) Issue: 4 Pages: 428-33
- DOI
  10.1007/s12185-012-1023-z
- NAID
  10030632677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04711, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-23591415
[Journal Article] Efficacy and safety of human adipose tissue-derived mesenchymal stem cells for supporting hematopoiesis.2012
- Author(s)
  Nishiwaki S
- Journal Title
  
  Int J Hematol.
  
  Volume: 96(3) Issue: 3 Pages: 295-300
- DOI
  10.1007/s12185-012-1140-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590887, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-23591415
[Journal Article] Mesenchymal stem cells stably transduced with a dominant-negative inhibitor of CCL2 greatly attenuate bleomycine-induced lung damage2011
- Author(s)
  斎藤繁紀
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 179 Issue: 3 Pages: 1088-1094
- DOI
  10.1016/j.ajpath.2011.05.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J04711, KAKENHI-PROJECT-23591382, KAKENHI-PROJECT-23659431
[Journal Article] Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF.2011
- Author(s)
  Kikuchi R, Takeshita K, Uchida Y, Kondo M, Cheng XW, Nakayama T, Yamamoto K, Matsushita T, Liao JK, Murohara T
- Journal Title
  
  Lab Invest.
  
  Volume: 91 Pages: 691-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591382
[Journal Article] Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notchl in a murine hindlimb ischemia model without induction of VEGF2011
- Author(s)
  Kikuchi R
- Journal Title
  
  Lab Invest
  
  Volume: 91 Issue: 5 Pages: 691-703
- DOI
  10.1038/labinvest.2011.5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-23591382
[Journal Article] Successful fertility management of a patient with factor V deficiency: planned transfusion of fresh frozen plasma under infertility treatment2011
- Author(s)
  Iwase A, Matsushita T
- Journal Title
  
  Fertil Steril
  
  Volume: 95(6) Issue: 6 Pages: 2124.e5-2124.e7
- DOI
  10.1016/j.fertnstert.2011.01.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591059, KAKENHI-PROJECT-23591382
[Journal Article] Successful fertility management of a patient with factor V deficiency: planned transfusion of fresh frozen plasma under infertility treatment.2011
- Author(s)
  Iwase A, Goto M, Manabe S, Hirokawa W, Kobayashi H, Nakahara T, Takikawa S, Kotani T, Sumigama S, Tsuda H, Nakayama T, Suzuki N, Matsushita T, Kikkawa F.
- Journal Title
  
  Fertil Steril.
  
  Volume: 95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591382
[Journal Article] Mesenchymal stem cells stably transduced with a dominant negative inhibitor of CCL2 greatly attenuate bleomycin-induced lung damage.2011
- Author(s)
  Saito S, Nakayama T*, Hashimoto N, Miyata Y, Egashira K, Nakao N, Nishiwaki S, Hasegawa M, Hasegawa Y, Naoe T
- Journal Title
  
  Am J Pathol.
  
  Volume: 179 Pages: 1088-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591382
[Journal Article] Adipose Tissue-Derived Mesenchymal Stem Cells Facilitate Hematopoiesis In Vitro and In Vivo2010
- Author(s)
  中尾典彦、中山享之、直江知樹
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 177(2) Pages: 547-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591118
[Journal Article] Adipose Tissue-Derived Mesenchymal Stem Cells Facilitate Hematopoiesis In Vitro and In Vivo.2010
- Author(s)
  中尾典彦、中山享之、八幡崇、六車ゆかり、齋藤繁紀、宮田泰彦、山本晃士、直江知樹
- Journal Title
  
  The American Journal of Pathology 177(2)
  
  Pages: 547-554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591118
[Patent] 間葉系幹細胞を含有する局所止血剤2023
- Inventor(s)
  中山享之、小川実加
- Industrial Property Rights Holder
  中山享之、小川実加
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-20K08721
[Presentation] Fibroblast Growth Factor-2 facilitates the growth and chemo-resistance of leukemia cells in the bone marrow by modulating osteoblast functions.2017
- Author(s)
  Nakayama T
- Organizer
  Keystone Symposia
- Place of Presentation
  Whistler, BC, Canada
- Year and Date
  2017-03-05
- Data Source
  KAKENHI-PROJECT-26461435
[Presentation] 洗浄血小板の有効性と課題2015
- Author(s)
  中山享之
- Organizer
  日本輸血学会東海支部会
- Place of Presentation
  三重県津市
- Year and Date
  2015-10-03
- Invited
- Data Source
  KAKENHI-PROJECT-26461435
[Presentation] Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions.2015
- Author(s)
  中山享之
- Organizer
  Keystone Symposia
- Place of Presentation
  Squaw creek, CA, USA
- Year and Date
  2015-04-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461435
[Presentation] Livedo vasculitis and popliteal artery occlusion in a patient with protein S deficiency2015
- Author(s)
  中山享之
- Organizer
  日本血液学会総会
- Place of Presentation
  石川県金沢市
- Year and Date
  2015-10-17
- Data Source
  KAKENHI-PROJECT-26461435
[Presentation] Stress augments insulin resistance and prothrombotic state: role of visceral adipose-derived monocyte chemoattractant protein-12014
- Author(s)
  Uchida Y, Takeshita K, Yamamoto K, Kikuchi R, Nakayama T, Nomura M, Cheng XW, Egashira K, Matsushita T, Nakamura H, Murohara T.
- Organizer
  Keystone symposia
- Place of Presentation
  BC, Canada
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] Stress augments insulin resistance and prothrombotic state : role of visceral adipose-derived CCL22013
- Author(s)
  Uchida Y, Takeshita K, Nakayama T.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] Mesenchymal stem cells stably transduced with a dominant negative inhibitor of CCL2 greatly attenuate bleomycin-induced lung damage2013
- Author(s)
  Nakayama T, Saito S, Naoe T
- Organizer
  第61回日本輸血・細胞療法学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomib2012
- Author(s)
  Nakayama T, Mizuno H, Naoe T
- Organizer
  第34回日本血栓止血学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] The effectiveness of macrophage-targeted therapy by dexamethasone palmitate for refractory GVHD2012
- Author(s)
  Nishiwaki S, Nakayama T, Naoe T.
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] Efficacy and safety of adipose tissue-derived mesenchymal stem cells for supporting hematopoiesis.2012
- Author(s)
  Takayuki Nakayama
- Organizer
  The 60th Annual Meeting of the Japanese Society of Transfusison Medicine and Cell therapy
- Place of Presentation
  Fukushima, Japan
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomib.2012
- Author(s)
  Takayuki Nakayama
- Organizer
  The 34th Annual Meeting of the Japanese Society of Thrombosis and Hemostasis
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] The effectiveness of macrophage-targeted therapy by dexamethasone palmitate for refractory GVHD2012
- Author(s)
  Takayuki Nakayama, Satoshi Nishiwaki, Makoto Murata, Tetsuya Nishida, Seitaro Terakura, Shigeki Saito, Tomoki Naoe et al.
- Organizer
  The 74th Annual Meeting of the Japanese Society of Hematology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] 造血支持を目的としたヒト脂肪組織由来間葉系幹細胞の有効性、安全性の検討2011
- Author(s)
  中山享之、中尾典彦、直江知樹
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591382
[Presentation] 脂肪組織由来間葉系幹細胞は、造血支持機能において骨髄由来のものより優れている。2009
- Author(s)
  中山享之、中尾典彦、直江知樹
- Organizer
  日本血液学会総会
- Place of Presentation
  京都市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591118
[Presentation] 脂肪組織由来間葉系幹細胞は、造血支持機能において骨髄由来のものより優れている2009
- Author(s)
  中山享之
- Organizer
  第71回日本血液学会総会
- Place of Presentation
  京都市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20591118
[Presentation] 間葉系幹細胞を用いた細胞療法の発展性
- Author(s)
  中山享之
- Organizer
  日本輸血細胞療法学会総会
- Place of Presentation
  奈良市
- Year and Date
  2014-05-15 – 2014-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-26461435
[Presentation] Effects of FGF2 on the leukemia microenvironment in the bone marrow
- Author(s)
  中山享之
- Organizer
  日本血液学会総会
- Place of Presentation
  大阪市
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26461435
[Presentation] Mast cells promote the growth of Hodgkin's lymphoma cell tumor by modifying the tumor microenvironment that can be perturbed by bortezomib
- Author(s)
  Nakayama T, Mizuno H, Naoe T
- Organizer
  Keystone Symposia
- Place of Presentation
  Vancouver, BC, Canada
- Data Source
  KAKENHI-PROJECT-23591382

1. YAMAMOTO Kouji (90362251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. NAOE Tomoki (50217634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. DEZAWA Mari (50272323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Takeshita Kyosuke (70444403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 冨田章裕 (80378215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 国崎祐哉 (80737099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 都築忍 (00342965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 片岡浩巳 (80398049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 丹羽利充 (20208268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐藤稔 (70449891)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宮原信明 (70335610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 谷口暁彦 (90751123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 肥後寿夫 (50818143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HANAMYRA Ichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. SUZUKI Susumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 高見昭良

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 松下正

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 舟羽利充

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 山本英範

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 西脇聡史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAYAMA Takayuki 中山 享之

中山 享之 ナカヤマ タカユキ

Research Projects

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Co-Researchers

慢性DICの病態解明と適切な治療法開発：XIII因子とDOACに着目してPrincipal Investigator

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ケモカイン抑制能を強化した新規間葉系幹細胞による慢性閉塞性肺疾患の細胞療法開発

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Analysis of metabolic pathways in adipose tissue-derived mesenchymal stem cells-hematopoietic stem cells: focus on anti-aging effectsPrincipal Investigator

Principal Investigator

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Pathophysiology of vascular injury via Notch signaling and metabolic reprogramming by urea toxins.

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analysis of the regulatory mechanism for the vascular niche to protect leukemia stem cells.Principal Investigator

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Analysis of the functions of MUSE in the lymphoma microenvironment.Principal Investigator

Principal Investigator

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Effects of FGF2 on the leukemia microenvironment in the bone marrowPrincipal Investigator

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Cell therapy using adipose tissue-derived mesenchymal stem cells for primary myelofibrosisPrincipal Investigator

Principal Investigator

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[Journal Article] Serum Produced from Expired Fresh Frozen Plasma and Cryosupernatant Supports the Proliferation of Human Cells: Cost-Effective Alternatives to Fetal Bovine Serum2023

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[Journal Article] Indoxyl Sulfate Activates NLRP3 Inflammasome to Induce Cardiac Contractile Dysfunction Accompanied by Myocardial Fibrosis and Hypertrophy2022

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[Journal Article] Pretreatment Immature Platelet Fraction as a Surrogate of Reticulated Platelets Predicts the Response to Corticosteroids in Adults with Immune Thrombocytopenia2021

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[Journal Article] Point‐of‐care nerve conduction device predicts the severity of diabetic polyneuropathy: A quantitative, but easy‐to‐use, prediction model2021

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[Journal Article] Alterations of retinal thickness measured by optical coherence tomography correlate with neurophysiological measures in diabetic polyneuropathy2021

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[Journal Article] Notch1 haploinsufficiency in mice accelerates adipogenesis2021

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NAKAYAMA Takayuki 中山享之

中山享之ナカヤマタカユキ