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URANO Yasuomi  浦野 泰臣

… Alternative Names

Urano Yasuomi  浦野 泰臣

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Researcher Number 00546674
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4901-1937
Affiliation (Current) 2025: 同志社大学, 生命医科学部, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 同志社大学, 生命医科学部, 准教授
2018 – 2021: 同志社大学, 生命医科学部, 准教授
2016 – 2017: 同志社大学, 生命医科学部, 助教
2009 – 2014: Doshisha University, 生命医科学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology
Except Principal Investigator
Basic Section 59020:Sports sciences-related / Eating habits
Keywords
Principal Investigator
脂質代謝 / アルツハイマー病 / 細胞死 / 細胞内輸送 / オキシステロール / 24S-hydroxycholesterol / ドラッグリポジショニング / ACAT (SOAT) / 酸化ステロール / 酸化コレステロール … More / 脂質 / 神経科学 / ガン / 筋萎縮性側索硬化症 / 食品性抗酸化物質 / 小胞体ストレス / ACAT / クルクミン / 神経変性疾患 / コレステロール / 痴呆 … More
Except Principal Investigator
抗酸化物質 / インスリンシグナル / 運動 / 酸化 / 超硫黄 / シグナル伝達 / 生体分子 / 脳神経疾患 / 脂質 / 食品 / 神経変性疾患 / 膜の流動性 / phospho-CaMKII / CaMKII / 酸化ストレス / 膜破綻 / ACAT1 / 24S-ヒドロキシコレステロール / 脂肪滴 / 小胞体ストレス / ビタミンE / アルツハイマー病 / 神経細胞死 / コレステロール / オキシステロール Less
  • Research Projects

    (8 results)
  • Research Products

    (85 results)
  • Co-Researchers

    (8 People)
  •  The mechanism of the regulation for optimized protective effect of exercise against diabetes mellitus

    • Principal Investigator
      野口 範子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Doshisha University
  •  食品性抗酸化物質によるオキシステロール誘導性細胞死抑制機構の解明と応用Principal Investigator

    • Principal Investigator
      浦野 泰臣
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Doshisha University
  •  Basic research on the development of therapeutic agents for Alzheimer's disease using Acyl-CoA:cholesterol acyltransferase inhibitorPrincipal Investigator

    • Principal Investigator
      Urano Yasuomi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Doshisha University
  •  Drug repositioning approaches for the development of new treatments for Alzheimer's diseasePrincipal Investigator

    • Principal Investigator
      Urano Yasuomi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Doshisha University
  •  Mechanism of inhibition of oxysterol-induced Alzheimer's disease by vitamin E

    • Principal Investigator
      Noguchi Noriko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Eating habits
    • Research Institution
      Doshisha University
  •  Screenings of amyloid beta production inhibitor via suppression of intracellular amyloid precursor protein trafficking.Principal Investigator

    • Principal Investigator
      URANO Yasuomi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Doshisha University
  •  Study for the mechanism linking intracellular amyloid precursor protein transport and cholesterol metabolismPrincipal Investigator

    • Principal Investigator
      URANO Yasuomi, 浦野 泰臣
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Doshisha University
  •  Study for the mechanism linking intracellular amyloid precursor protein transport and lipid metabolismPrincipal Investigator

    • Principal Investigator
      URANO Yasuomi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Doshisha University

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

  • [Journal Article] Enzymatically Formed Oxysterols and Cell Death2023

    • Author(s)
      Urano Yasuomi、Noguchi Noriko
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 1440 Pages: 193-211

    • DOI

      10.1007/978-3-031-43883-7_10

    • ISBN
      9783031438820, 9783031438837
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K10902
  • [Journal Article] Therapeutic effect of a novel curcumin derivative GT863 on a mouse model of amyotrophic lateral sclerosis2021

    • Author(s)
      Kato Hajime、Sato Hiroyasu、Okuda Michiaki、Wu Jun、Koyama Shingo、Izumi Yasuhiko、Waku Tomonori、Iino Mitsuyoshi、Aoki Masashi、Arawaka Shigeki、Ohta Yasuyuki、Ishizawa Kenichi、Kawasaki Kanan、Urano Yasuomi、Miyasaka Tomohiro、Noguchi Noriko、Kume Toshiaki、Akaike Akinori、Sugimoto Hachiro、Kato Takeo
    • Journal Title

      Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

      Volume: Dec Issue: 7-8 Pages: 1-7

    • DOI

      10.1080/21678421.2021.2012699

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07093, KAKENHI-PROJECT-19K07112
  • [Journal Article] NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition2021

    • Author(s)
      Waku Tsuyoshi、Hagiwara Toru、Tamura Natsuko、Atsumi Yuri、Urano Yasuomi、Suzuki Mikiko、Iwami Takuya、Sato Katsuya、Yamamoto Masayuki、Noguchi Noriko、Kobayashi Akira
    • Journal Title

      iScience

      Volume: 24 Issue: 10 Pages: 103180-103180

    • DOI

      10.1016/j.isci.2021.103180

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07093, KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-21K19743, KAKENHI-PROJECT-23K20318
  • [Journal Article] Different functions of vitamin E homologues in the various types of cell death induced by oxysterols2021

    • Author(s)
      Suzuki Atsuki、Urano Yasuomi、Ishida Tomohisa、Noguchi Noriko
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 176 Pages: 356-365

    • DOI

      10.1016/j.freeradbiomed.2021.10.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Journal Article] Identification of a novel endogenous long non-coding RNA that inhibits selenoprotein P translation2021

    • Author(s)
      Mita Yuichiro、Uchida Risa、Yasuhara Sayuri、Kishi Kohei、Hoshi Takayuki、Matsuo Yoshitaka、Yokooji Tadashi、Shirakawa Yoshino、Toyama Takashi、Urano Yasuomi、Inada Toshifumi、Noguchi Noriko、Saito Yoshiro
    • Journal Title

      Nucleic Acids Research

      Volume: 49 Issue: 12 Pages: 6893-6907

    • DOI

      10.1093/nar/gkab498

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07093, KAKENHI-PROJECT-19K11770, KAKENHI-PUBLICLY-20H05491, KAKENHI-PROJECT-21K19321, KAKENHI-PLANNED-21H05270, KAKENHI-PROJECT-20H00488
  • [Journal Article] Astrocytes release glutamate via cystine/glutamate antiporter upregulated in response to increased oxidative stress related to sporadic amyotrophic lateral sclerosis.2020

    • Author(s)
      Kazama M, Kato Y, Kakita A, Noguchi N, Urano Y, Masui K, Niida-Kawaguchi M, Yamamoto T, Watabe K, Kitagawa K, Shibata N.
    • Journal Title

      Neuropathology

      Volume: 40 Issue: 6 Pages: 587-598

    • DOI

      10.1111/neup.12716

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06507, KAKENHI-PROJECT-19K07093
  • [Journal Article] Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation2020

    • Author(s)
      Urano Yasuomi、Takahachi Mina、Higashiura Ryo、Fujiwara Hitomi、Funamoto Satoru、Imai So、Futai Eugene、Okuda Michiaki、Sugimoto Hachiro、Noguchi Noriko
    • Journal Title

      Cells

      Volume: 9 Issue: 2 Pages: 349-349

    • DOI

      10.3390/cells9020349

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06558, KAKENHI-PROJECT-19K07093
  • [Journal Article] Brain Targeting of Acyl-CoA:Cholesterol O-Acyltransferase-1 Inhibitor K-604 via the Intranasal Route Using a Hydroxycarboxylic Acid Solution2019

    • Author(s)
      Shibuya Kimiyuki、Morikawa Shigeru、Miyamoto Masayoshi、Ogawa Shin-ichiro、Tsunenari Yoshihiko、Urano Yasuomi、Noguchi Noriko
    • Journal Title

      ACS Omega

      Volume: 4 Issue: 16 Pages: 16943-16955

    • DOI

      10.1021/acsomega.9b02307

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Journal Article] 24(S)-Hydroxycholesterol induces ER dysfunction-mediated unconventional cell death2019

    • Author(s)
      Urano Yasuomi、Ho Vo Diep-Khanh、Hirofumi Araki、Noguchi Noriko
    • Journal Title

      Cell Death Discovery

      Volume: 5 Issue: 1

    • DOI

      10.1038/s41420-019-0192-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Journal Article] Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation2018

    • Author(s)
      Kimura Yuki、Asa Minori、Urano Yasuomi、Saito Yoshiro、Nishikawa Kiyotaka、Noguchi Noriko
    • Journal Title

      Biochimie

      Volume: 153 Pages: 203-209

    • DOI

      10.1016/j.biochi.2018.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08254, KAKENHI-PROJECT-17H03821
  • [Journal Article] Tocopherol suppresses 24(S)-hydroxycholesterol-induced cell death via inhibition of CaMKII phosphorylation.2018

    • Author(s)
      Yuki Kimura, Minori Asa, Yasuomi Urano, Yoshiro Saito, Kiyotaka Nishikawa, Noriko Noguchi
    • Journal Title

      Biochimie

      Volume: 153 Pages: 203-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Journal Article] 6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway2018

    • Author(s)
      Urano Yasuomi、Mori Chinatsu、Fuji Ayano、Konno Keito、Yamamoto Takayuki、Yashirogi Shohei、Ando Mayu、Saito Yoshiro、Noguchi Noriko
    • Journal Title

      Autophagy

      Volume: 14 Issue: 11 Pages: 1943-1958

    • DOI

      10.1080/15548627.2018.1493043

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08254, KAKENHI-PROJECT-17H03821
  • [Journal Article] Decrease of Amyloid-β Levels by Curcumin Derivative via Modulation of Amyloid-β Protein Precursor Trafficking.2017

    • Author(s)
      Kotani Rina, Urano Yasuomi, Sugimoto Hachiro, Noguchi Noriko
    • Journal Title

      Journal of Alzheimer's Disease

      Volume: 56 Issue: 2 Pages: 529-542

    • DOI

      10.3233/jad-160794

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Journal Article] Effect of vitamin E on 24( S )-hydroxycholesterol-induced necroptosis-like cell death and apoptosis2017

    • Author(s)
      Nakazawa Takaya、Miyanoki Yuta、Urano Yasuomi、Uehara Madoka、Saito Yoshiro、Noguchi Noriko
    • Journal Title

      The Journal of Steroid Biochemistry and Molecular Biology

      Volume: 169 Pages: 69-76

    • DOI

      10.1016/j.jsbmb.2016.03.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Journal Article] Effect of vitamin E on 24(S)-hydroxycholesterol-induced necroptosis-like cell death and apoptosis.2017

    • Author(s)
      Takaya Nakazawa, Yuta Miyanoki, Yasuomi Urano, Madoka Uehara, Yoshiro Saito, Noriko Noguchi
    • Journal Title

      J. Steroid Biochem. Mol. Biol.

      Volume: 169 Pages: 69-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Journal Article] Esterification of 24(S)-hydroxycholesterol induces formation of atypical lipid droplet-like structures, leading to neuronal cell death2016

    • Author(s)
      Takabe W, Urano Y, Vo D-K H, Shibuya K, Tanno M, Kitagishi H, Fujimoto T, Noguchi N
    • Journal Title

      J Lipid Res

      Volume: 57 Issue: 11 Pages: 2005-2014

    • DOI

      10.1194/jlr.m068775

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-15H02500, KAKENHI-PROJECT-16K08254
  • [Journal Article] Synthesis of 24(S)-hydroxycholesterol esters responsible for the induction of neuronal cell death.2016

    • Author(s)
      Shibuya K, Watanabe T, Urano Y, Takabe W, Noguchi N, Kitagishi H.
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 24 Issue: 11 Pages: 2559-2566

    • DOI

      10.1016/j.bmc.2016.04.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26850089, KAKENHI-PROJECT-16K08254
  • [Journal Article] 24(S)-Hydroxycholesterol induces RIPK1-dependent but MLKL-independent cell death in the absence of caspase-8.2015

    • Author(s)
      Vo DK, Urano Y, Takabe W, Saito Y, Noguchi N.
    • Journal Title

      Steroids

      Volume: 印刷中 Pages: 230-237

    • DOI

      10.1016/j.steroids.2015.02.007

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25830041, KAKENHI-PROJECT-25670084, KAKENHI-PROJECT-26850089
  • [Journal Article] Diverse functions of 24(S)-hydroxycholesterol in the brain.2014

    • Author(s)
      Noriko Noguchi, Yoshiro Saito, and Yasuomi Urano
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 446 Issue: 3 Pages: 692-696

    • DOI

      10.1016/j.bbrc.2014.02.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25292078, KAKENHI-PROJECT-25830041
  • [Journal Article] Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking.2013

    • Author(s)
      Urano Y et al
    • Journal Title

      FASEB Journal

      Volume: 27 Issue: 10 Pages: 4305-4315

    • DOI

      10.1096/fj.13-231456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25830041
  • [Journal Article] 24(S)-Hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis2011

    • Author(s)
      Yamanaka K., Saito Y., Yamamori T., Urano Y., Noguchi N.
    • Journal Title

      J. Biol. Chem. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Journal Article] 24(S)-Hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis2011

    • Author(s)
      Yamanaka K., Saito Y., Yamamori T., Urano Y., Noguchi N
    • Journal Title

      J. Biol. Chem.

      Volume: vol.268 Pages: 24666-24673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Journal Article] Intracellular transport of low-density lipoprotein-derived cholesterol2010

    • Author(s)
      Urano Y
    • Journal Title

      Seikagaku

      Volume: 82 Pages: 411-415

    • NAID

      10026425942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Journal Article] Single chain variable fragment against nicastrin inhibits the gamma-secretase activity.2009

    • Author(s)
      Hayashi I, Takatori S, Urano Y, et al
    • Journal Title

      Journal of Biological Chemistry 284

      Pages: 27838-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Journal Article] Acyl-coenzyme A : cholesterol acyltransferases.2009

    • Author(s)
      Chang TY, Li BL, Chang CC, Urano Y.
    • Journal Title

      American Journal of Physiology, Endocrinology and Metabolism 297

      Pages: 1-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Patent] 25-OHC誘導性グリア細胞死の抑制剤2021

    • Inventor(s)
      浦野泰臣、野口範子、岩垣あなん
    • Industrial Property Rights Holder
      学校法人同志社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-022287
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Patent] 胆道がん又は皮膚がんの予防又は治療剤2020

    • Inventor(s)
      浦野泰臣、野口範子、岩田実姫
    • Industrial Property Rights Holder
      学校法人同志社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-185817
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Patent] Aβ産生抑制剤2019

    • Inventor(s)
      浦野泰臣、野口範子、髙八美菜
    • Industrial Property Rights Holder
      学校法人同志社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-205225
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Patent] 25-OHC誘導性細胞死の抑制剤、並びに、神経原性疾患の予防及び/又は治療のための薬剤2019

    • Inventor(s)
      浦野泰臣、野口範子、石田智久
    • Industrial Property Rights Holder
      学校法人同志社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-105214
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Patent] 経鼻投与用医薬組成物2017

    • Inventor(s)
      浦野泰臣、野口範子
    • Industrial Property Rights Holder
      浦野泰臣、野口範子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Patent] 経鼻投与用医薬組成物2016

    • Inventor(s)
      浦野泰臣、野口範子、渋谷公幸、森川滋
    • Industrial Property Rights Holder
      浦野泰臣、野口範子、渋谷公幸、森川滋
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-222605
    • Filing Date
      2016-11-15
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Patent] 細胞死抑制剤2012

    • Inventor(s)
      浦野泰臣
    • Industrial Property Rights Holder
      学校法人同志社
    • Industrial Property Number
      2012-242950
    • Filing Date
      2012-11-02
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Patent] 細胞死抑制剤2012

    • Inventor(s)
      浦野泰臣 他
    • Industrial Property Rights Holder
      学校法人同志社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-11-02
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] 25-Hydroxycholesterolによるフェロトーシス誘導機構とビタミンEの抑制効果2024

    • Author(s)
      浦野泰臣,岩垣あなん,武石安理沙,野口範子
    • Organizer
      第33回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-23K10902
  • [Presentation] 多様な細胞死から見出されたビタミンEの新規抑制機序2023

    • Author(s)
      野口範子, 浦野泰臣
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K10902
  • [Presentation] シュワン細胞における25-hydroxycholesterolによるFerroptosis誘導機構の解析2023

    • Author(s)
      浦野泰臣、野口範子
    • Organizer
      第65回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-23K10902
  • [Presentation] 25-Hydroxycholesterol induces ferroptosis via downregulation of mevalonate pathway in Schwann cells2021

    • Author(s)
      浦野 泰臣、岩垣あなん、野口 範子
    • Organizer
      10th ENOR SYMPOSIUM
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] マウスシュワン細胞 IMS32における25-hydroxycholesterolによるFerroptosis誘導機構の解析2021

    • Author(s)
      岩垣あなん、浦野 泰臣、野口 範子
    • Organizer
      第74回日本酸化ストレス学会・第21回日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] マウスシュワン細胞 IMS32における25-hydroxycholesterolによるFerroptosis誘導機構の解析2021

    • Author(s)
      岩垣あなん、浦野 泰臣、野口 範子
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] ACAT1選択的阻害剤によるAβ産生抑制メカニズムの解析2021

    • Author(s)
      スウ ショウゲツ, 浦野 泰臣, 野口 範子
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] 運動ニューロン様細胞NSC-34における25-OHC誘導性細胞死機構の解明2020

    • Author(s)
      石田智久、浦野泰臣、野口範子
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] ヒト肝癌細胞HepG2とヒト表皮角化細胞HaCaTにおける 25-hydroxycholesterol誘導性細胞死機構の解析2020

    • Author(s)
      鈴木淳生、浦野泰臣、野口範子
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] Curcumin誘導体GT863の基質選択的なAβ産生抑制機構の解明2019

    • Author(s)
      高八美菜, 浦野泰臣, 奥田充顕, 杉本八郎, 野口範子
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] Induction of cell death by 25-hydroxycholesterol is dependent on activity of ACAT12019

    • Author(s)
      石田智久、浦野泰臣、野口範子
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] Accumulation of 24(S)-hydroxycholesterol esters causes disruption of endoplasmic reticulum membrane integrity2019

    • Author(s)
      藪田和生、浦野泰臣、野口範子
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] Oxysterol-induced unconventional cell death mechanism2019

    • Author(s)
      浦野泰臣
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] Effects of 24(S)-hydroxycholesterol and 25-hydroxycholesterol in different cell types2019

    • Author(s)
      野口範子、浦野泰臣、石田智久、鈴木淳生
    • Organizer
      9th The European Network for Oxysterol Research Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] 脂質が誘導する小胞体ストレスとビタミンE2019

    • Author(s)
      木村勇輝、浦野泰臣、斎藤芳郎、野口範子
    • Organizer
      第30回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] ビタミンE疎水部構造の違いと膜相分離2019

    • Author(s)
      中谷祐将、下川直史、浦野泰臣、野口範子、高木昌宏
    • Organizer
      第71回日本生物工学会大会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] 25-hydroxycholesterol-induced cell death mechanism in HepG2 cells and HaCaT cells2019

    • Author(s)
      鈴木淳生、浦野泰臣、野口範子
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] 脂質が誘導する小胞体ストレスとビタミンE2019

    • Author(s)
      木村勇輝、浦野泰臣、斎藤芳郎、野口範子
    • Organizer
      第30回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] ビタミンEによる24S-OHC誘導性細胞死抑制機構の解析2019

    • Author(s)
      鈴木淳生、木村勇輝、浦野泰臣、野口範子
    • Organizer
      第31回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-19K07093
  • [Presentation] ER stress plays important roles in 24S-hydroxycholesterol-induced neuronal cell death2018

    • Author(s)
      Noguchi N, Urano Y, Vo Ho D-K, Araki H, and Kimura Y
    • Organizer
      7th ENOR SYMPOSIUM, Oxysterols and sterol derivatives in health and disease
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] 脳特異的オキシステロール24S-hydroxycholesterolによる神経細胞死誘導における小胞体の関与2018

    • Author(s)
      浦野泰臣、野口範子
    • Organizer
      第27回日本Cell death学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] 24S-ヒドロキシコレステロールが誘導する神経細胞死に対するビタミンEの抑制機構の解析2018

    • Author(s)
      木村勇輝、浦野泰臣、野口範子
    • Organizer
      第29回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] Curcumin誘導体GT863のAβ産生抑制機構の解明2018

    • Author(s)
      高八美菜、浦野泰臣、杉本八郎、野口範子
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] 24S-Hydroxycholesterol誘導性細胞死に対するビタミンEの効果2018

    • Author(s)
      木村勇輝、浦野泰臣、西川喜代孝、野口範子
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] Curcumin誘導体GT863のAβ産生抑制機構の解明2018

    • Author(s)
      高八美菜、浦野泰臣、杉本八郎、野口範子
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 24S-ヒドロキシコレステロールが誘導する神経細胞死に対するビタミンEの抑制機構の解析2018

    • Author(s)
      木村 勇輝、浦野泰臣、野口範子
    • Organizer
      第29回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] 24S-Hydroxycholesterol誘導性細胞死に対するビタミンEの効果2018

    • Author(s)
      木村勇輝、浦野泰臣、西川喜代孝、野口 範子
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 脳特異的オキシステロール24S-hydroxycholesterolによる神経細胞死誘導における小胞体の関与2018

    • Author(s)
      浦野泰臣、野口範子
    • Organizer
      第27回日本Cell death学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 脳特異的オキシステロール24S-hydroxycholesterolによる神経細胞死誘導機構の解析2017

    • Author(s)
      浦野泰臣、野口範子
    • Organizer
      第59回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 24S-Hydroxycholesterol誘導性神経細胞死に対するビタミンEの効果2017

    • Author(s)
      木村勇輝,浦野泰臣,野口範子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 24S-ヒドロキシコレステロールが誘導する神経細胞死に対するビタミンE同族体の抑制作用のちがい2017

    • Author(s)
      木村勇輝、宮軒勇太、浦野泰臣、野口範子
    • Organizer
      第28回 ビタミンE研究会
    • Place of Presentation
      東洋大学白山キャンパス(東京都文京区
    • Year and Date
      2017-02-20
    • Data Source
      KAKENHI-PROJECT-16K00882
  • [Presentation] 24S-Hydroxycholesterol誘導性神経細胞死への小胞体ストレスの関与2017

    • Author(s)
      荒木宏文,浦野泰臣,Diep Khanh H Vo,野口範子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 一酸化炭素放出分子を用いた一酸化炭素によるAβ産生への影響の解析2017

    • Author(s)
      棒谷夏希,浦野泰臣,野口範子
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] 24S-Hydroxycholesterol誘導性神経細胞死へのIRE1の関与2016

    • Author(s)
      荒木 宏文、浦野 泰臣、Diep Khanh H Vo、野口 範子
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K08254
  • [Presentation] Mechanisms of neuronal cell death induced by 24(S)-hydroxycholesterol2014

    • Author(s)
      Noguchi N., Vo DK., Takabe W., Urano Y., Saito Y.
    • Organizer
      4th The European Network for Oxysterol Research Symposium
    • Place of Presentation
      COIMBRA(ポルトガル)
    • Year and Date
      2014-09-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-25830041
  • [Presentation] 脳特異的オキシステロール24S-hydroxycholesterolによる細胞死メカニズムの解析2014

    • Author(s)
      浦野泰臣,山中一哲,高部稚子,斎藤芳郎,野口範子
    • Organizer
      第23回日本Cell Death学会学術集会
    • Place of Presentation
      東京医科歯科大学(東京)
    • Year and Date
      2014-07-18
    • Data Source
      KAKENHI-PROJECT-25830041
  • [Presentation] Amyloid β産生抑制効果を有するクルクミン誘導体の作用機序の解明2014

    • Author(s)
      小谷理奈、浦野泰臣、杉本八郎、野口範子
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-25830041
  • [Presentation] Novel insights of brain-specific produced oxysterol in neurodegenerative diseases.2013

    • Author(s)
      Noguchi N., Yamanaka K., Takabe W., Urano Y., Saito Y.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25830041
  • [Presentation] Amyloid β産生を抑制するクルクミン誘導体の同定とそのメカニズムの解明2013

    • Author(s)
      小谷理奈, 浦野泰臣, 杉本八郎, 野口範子
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-25830041
  • [Presentation] アミロイド前駆体タンパク質細胞内輸送へのオキシステロールの関与機構の解明2012

    • Author(s)
      浦野泰臣,野口範子
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] 24(S)-Hydroxycholesterolにより誘導されるNecroptosis (プログラムネクローシス) を介する神経細胞死2011

    • Author(s)
      山中一哲、斎藤芳郎、山盛徹、浦野泰臣、野口範子
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking2011

    • Author(s)
      浦野泰臣
    • Organizer
      第30回内藤コンファレンス
    • Place of Presentation
      北海道
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] Suppression of amyloid-β production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking2011

    • Author(s)
      浦野泰臣
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] Suppression of amyloid-beta production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking.2011

    • Author(s)
      浦野泰臣
    • Organizer
      第30回内藤コンファレンス
    • Place of Presentation
      シャトレーゼガトーキングダムサッポロ (北海道)
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] Suppression of amyloid-beta production by 24S-hydroxycholesterol via inhibition of intracellular amyloid precursor protein trafficking.2011

    • Author(s)
      浦野泰臣
    • Organizer
      第84回日本生化学会大会(招待講演)
    • Place of Presentation
      国立京都国際会館 (京都)
    • Data Source
      KAKENHI-PROJECT-23700428
  • [Presentation] パーキンソン病関連分子DJ-1の細胞外分泌メカニズムの解析2010

    • Author(s)
      森千夏、浦野泰臣, 他
    • Organizer
      BMB2010、日本分子生物学会、日本生化学会合同大会
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Presentation] 24(S)-Hydroxycholesterol induces SH-SY5Y cell death via necroptosis.2010

    • Author(s)
      山中一哲、斎藤芳郎、浦野泰臣、野口範子
    • Organizer
      Society for Free Radical Biology and Medicine
    • Place of Presentation
      Orland, FL (USA)
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Presentation] 24S-hydroxycholesterolによる適応反応を介したストレス耐性の誘導2009

    • Author(s)
      伊藤早陽子、斎藤芳郎、浦野泰臣、野口範子
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Presentation] LDL由来コレステロールの細胞内輸送の解析2009

    • Author(s)
      浦野泰臣, 他
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      ウィルあいち(愛知県)
    • Year and Date
      2009-07-31
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Presentation] 24S-hydroxycholesterolによる適応反応を介したストレス耐性の誘導2009

    • Author(s)
      伊藤早陽子、浦野泰臣, 他
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Presentation] 24S-hydroxycholesterolによる神経細胞傷害メカニズムの解析2009

    • Author(s)
      山中一哲、浦野泰臣, 他
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      ウィルあいち(愛知県)
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-21800075
  • [Presentation] アミロイド前駆体タンパク質細胞内輸送へのオキシステロールの関与機構の解明

    • Author(s)
      浦野泰臣
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23700428
  • 1.  Noguchi Noriko (40198578)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  斎藤 芳郎 (70357060)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  URANO Yasuomi (22546674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  三田 雄一郎 (70609122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  FUTAI Eugene
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  渡部 和彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  藤本 豊士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  高部 稚子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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