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Tomihari Mizuki  富張 瑞樹

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TOMIHARI Mizuki  富張 瑞樹

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Researcher Number 00552754
Other IDs
Affiliation (Current) 2025: 大阪公立大学, 大学院獣医学研究科 , 准教授
Affiliation (based on the past Project Information) *help 2024: 大阪公立大学, 大学院獣医学研究科, 准教授
2014 – 2017: 帯広畜産大学, 畜産学部, 准教授
2013 – 2014: 帯広畜産大学, 畜産学部, 講師
2009 – 2013: Obihiro University of Agriculture and Veterinary Medicine, 畜産学部, 助教
Review Section/Research Field
Principal Investigator
Veterinary medical science / Clinical veterinary science / Basic Section 42020:Veterinary medical science-related
Except Principal Investigator
Veterinary medical science / Clinical veterinary science
Keywords
Principal Investigator
犬 / 腫瘍 / 悪性黒色腫 / 免疫学 / 癌 / 臨床 / 獣医学 / 免疫療法 / 生体分子 / ゲノム育種価 … More / 股関節形成不全 / 腫瘍関連抗原 / 遺伝性疾患 / 分子 / 獣医 / 遺伝子変異 / 肥満細胞腫 / 家族性発症 / 遺伝子 / 肥満細胞種 / 分子生物学 … More
Except Principal Investigator
犬 / レオウイルス / 治療 / ガン / 免疫 / 腫瘍 / DNA vaccine / oncolytic virotherapy / immune checkpoint / cancer / dog / Oncogene addiction / ダサチニブ / キナーゼ / oncogene addiction / 組織球性肉腫 Less
  • Research Projects

    (7 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (6 People)
  •  Investigation of a new prediction model using genomic breeding values ​​for canine hip dysplasiaPrincipal Investigator

    • Principal Investigator
      富張 瑞樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Osaka Metropolitan University
  •  Basic research of new molecular target genes in canine mast cell tumorPrincipal Investigator

    • Principal Investigator
      TOMIHARI MIZUKI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Obihiro University of Agriculture and Veterinary Medicine
  •  Development of the combined immune-modulatory therapies for canine cancer

    • Principal Investigator
      MIZUNO TAKUYA
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Yamaguchi University
  •  A study of tumor-specific T cell therapy for canine melanoma cell lines.Principal Investigator

    • Principal Investigator
      TOMIHARI MIZUKI
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Obihiro University of Agriculture and Veterinary Medicine
  •  Analysis of oncogene addiction and development of molecular-targeted therapy for small animal tumours

    • Principal Investigator
      BONKOBARA Makoto
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Nippon Veterinary and Life Science University
  •  Breaking immunological tolerance to canine malignant melanoma using anti-Gpnmb antibody and various antigen peptides associated with tumor.Principal Investigator

    • Principal Investigator
      TOMIHARI Mizuki
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Obihiro University of Agriculture and Veterinary Medicine
  •  Breaking immunological tolerance to canine malignant melanoma by inhibition of Gpnmb expression : a new approach for melanoma immunotherapyPrincipal Investigator

    • Principal Investigator
      TOMIHARI Mizuki
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Clinical veterinary science
    • Research Institution
      Obihiro University of Agriculture and Veterinary Medicine

All 2017 2016 2015 2013 2010 2009 Other

All Journal Article Presentation

  • [Journal Article] Gene and protein expression of a soluble form of CTLA-4 in a healthy dog2017

    • Author(s)
      Michihito Tagawa, Yuhei Yamamoto, Genya Shimbo, Aiko Iguchi, Xuenan Xuan, Mizuki Tomihari, Kazuro Miyahara
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 79 Issue: 5 Pages: 871-875

    • DOI

      10.1292/jvms.16-0583

    • NAID

      130007331474

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18788, KAKENHI-PROJECT-15K07736
  • [Journal Article] Influence of transfusion of lymphokine-activated T killer cells on inflammatory responses in dogs after laparotomy2016

    • Author(s)
      Mie K, Tomihari M, Hoshi K, Nakamura T, Yamaguchi T, Miyahara K, Shimada T.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 78 Issue: 4 Pages: 579-585

    • DOI

      10.1292/jvms.15-0626

    • NAID

      130007331497

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07736
  • [Journal Article] A comparison of the immunological effects of propofol and isoflurane for maintenance of anesthesia in healthy dogs2015

    • Author(s)
      Tomihari M, Nishihara A, Shimada T, Yanagawa M, Miyoshi M, Miyahara K, Oishi A.
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 77 Issue: 10 Pages: 1227-1233

    • DOI

      10.1292/jvms.14-0611

    • NAID

      130005107584

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25850204
  • [Journal Article] The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease.2013

    • Author(s)
      Chung JS, Tomihari M, Tamura K, Kojima T, Cruz PD Jr., Ariizumi K.
    • Journal Title

      Immunology

      Volume: 138(2) Pages: 173-82

    • Data Source
      KAKENHI-PROJECT-23780317
  • [Journal Article] The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease.2013

    • Author(s)
      Chung JS, Tomihari M, Tamura K, Kojima T, Cruz PD Jr, Ariizumi K
    • Journal Title

      Immunology.

      Volume: 138(2) Issue: 2 Pages: 173-182

    • DOI

      10.1111/imm.12027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23780317, KAKENHI-PROJECT-24380173
  • [Journal Article] Depleting syndecan-4+ T lymphooytes usingt toxin-bearing dendritic cell-associated heparan suifate protenglycan-depedent integrin ligand:a new opportunity for treating activated T cell-driven disease.2010

    • Author(s)
      Akiyoshi H, Chung JS, Tomihari M, ほか2名
    • Journal Title

      J Immunol.

      Volume: 184(7) Pages: 3554-3561

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] Depleting syndecan-4+ T lymphocytes using toxin-bearing dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand : a new opportunity for treating activated T cell-driven disease.2010

    • Author(s)
      Akiyoshi H, Chung JS, Tomihari M, Cruz PD, Jr, Ariizumi K.
    • Journal Title

      J Immunol. 184(7)

      Pages: 3554-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells.2010

    • Author(s)
      Tomihari M, ほか4名
    • Journal Title

      Cancer Res.

      Volume: 70(14) Pages: 5778-5787

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells.2010

    • Author(s)
      Tomihari M, Chung JS, Akiyoshi H, Cruz PD, Jr, Ariizumi K.
    • Journal Title

      Cancer Res. 70(14)

      Pages: 5778-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses.2009

    • Author(s)
      Chung JS, Bonkobara M, Tomihari M, Cruz PD, Jr, Ariizumi K.
    • Journal Title

      Eur J Immunol. 39(4)

      Pages: 965-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-denendent fashion.2009

    • Author(s)
      Tomihari M, ほか4名
    • Journal Title

      Exp Dermatol. 18(7)

      Pages: 586-595

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function.2009

    • Author(s)
      Chung JS, Yudate T, Tomihari M, Akiyoshi H, Cruz PD, Jr, Ariizumi K.
    • Journal Title

      J Immunol. 183(8)

      Pages: 5190-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function.2009

    • Author(s)
      Chung JS, Tomihari M, ほか4名
    • Journal Title

      J Immunol. 183(8)

      Pages: 5190-5198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion.2009

    • Author(s)
      Tomihari M, Hwang SH, Chung JS, Cruz PD, Jr, Ariizumi K.
    • Journal Title

      Exp Dermatol. 18(7)

      Pages: 586-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Journal Article] The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell response.2009

    • Author(s)
      Chung JS, Tomihari M, ほか3名
    • Journal Title

      Eur J Immunol. 39(4)

      Pages: 965-974

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Presentation] 家族性発症を認めた犬の肥満細胞腫症例における遺伝学的検討2015

    • Author(s)
      富張瑞樹
    • Organizer
      平成26年度日本獣医師会獣医学術学会年次大会
    • Place of Presentation
      岡山
    • Year and Date
      2015-02-13
    • Data Source
      KAKENHI-PROJECT-25850204
  • [Presentation] 帯広畜産大学動物医療センターにおける活性化自己リンパ球療法の現状と問題点2013

    • Author(s)
      富張瑞樹
    • Organizer
      第2回動物臨床免疫療法研究会
    • Place of Presentation
      大阪府立大学、りんくうキャンパス(大阪府泉佐野市りんくう往来北1番地の58)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25850204
  • [Presentation] Syndecan-4 is an important negative regulator of T cell immunity and a potentially useful target for treating diseases resulting from such immunity.2010

    • Author(s)
      Chung JS, Tomihari M, Akiyoshi H, Cruz PD, Jr, Ariizumi K
    • Organizer
      Society for Investigative Dermatology, 70^<th> annual meeting
    • Place of Presentation
      Atlanta, Georgia, USA
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Presentation] Exploiting the DC-HIL/syndecan-4 pathway to treat cutaneous T cell lymphoma.2009

    • Author(s)
      Chung JS, Yudate T, Tomihari M, Cruz PD, Jr, Ariizumi K
    • Organizer
      Society for Investigative Dermatology, 69^<th> annual meeting
    • Place of Presentation
      Montreal, Canada, USA
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Presentation] Exploiting the DC-HIL/syndecan-4 pathway to treat cutaneous T cell lymphoma2009

    • Author(s)
      Chung JS, Tomihari M, ほか4名
    • Organizer
      Society for Investigative Dermatology, 69^<th> annual meeting
    • Place of Presentation
      Montreal, Canada
    • Data Source
      KAKENHI-PROJECT-21880008
  • [Presentation] 活性化自己リンパ球療法を行った平滑筋肉腫の犬の1症例

    • Author(s)
      ○富張瑞樹、 東野 崇、 三重慧一郎、 三好雅史、 宮原和郎、 嶋田照雅
    • Organizer
      平成23年度北海道獣医学術学会北海道地区学会・北海道獣医師大会
    • Place of Presentation
      北海道大学
    • Data Source
      KAKENHI-PROJECT-23780317
  • 1.  BONKOBARA Makoto (50343611)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  TAZAKI Hiroyuki (80231405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  OMI Toshinori (40296091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  SHIMADA Takashi (20125074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  MIZUNO TAKUYA (90398826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  中川 貴之 (40447363)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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