Tomihari Mizuki 富張瑞樹

… Alternative Names

TOMIHARI Mizuki 富張瑞樹

Less

Researcher Number	00552754
Other IDs
Affiliation (Current)	2025: 大阪公立大学, 大学院獣医学研究科 , 准教授
Affiliation (based on the past Project Information) *help	2024: 大阪公立大学, 大学院獣医学研究科, 准教授 2014 – 2017: 帯広畜産大学, 畜産学部, 准教授 2013 – 2014: 帯広畜産大学, 畜産学部, 講師 2009 – 2013: Obihiro University of Agriculture and Veterinary Medicine, 畜産学部, 助教
Review Section/Research Field	Principal Investigator Veterinary medical science / Clinical veterinary science / Basic Section 42020:Veterinary medical science-related Except Principal Investigator Veterinary medical science / Clinical veterinary science
Keywords	Principal Investigator 犬 / 腫瘍 / 悪性黒色腫 / 免疫学 / 癌 / 臨床 / 獣医学 / 免疫療法 / 生体分子 / ゲノム育種価 … More / 股関節形成不全 / 腫瘍関連抗原 / 遺伝性疾患 / 分子 / 獣医 / 遺伝子変異 / 肥満細胞腫 / 家族性発症 / 遺伝子 / 肥満細胞種 / 分子生物学 … More Except Principal Investigator 犬 / レオウイルス / 治療 / ガン / 免疫 / 腫瘍 / DNA vaccine / oncolytic virotherapy / immune checkpoint / cancer / dog / Oncogene addiction / ダサチニブ / キナーゼ / oncogene addiction / 組織球性肉腫 Less

Investigation of a new prediction model using genomic breeding values for canine hip dysplasiaPrincipal Investigator
- Principal Investigator
  
  富張瑞樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
Basic research of new molecular target genes in canine mast cell tumorPrincipal Investigator
- Principal Investigator
  
  TOMIHARI MIZUKI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Development of the combined immune-modulatory therapies for canine cancer
- Principal Investigator
  
  MIZUNO TAKUYA
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Yamaguchi University
A study of tumor-specific T cell therapy for canine melanoma cell lines.Principal Investigator
- Principal Investigator
  
  TOMIHARI MIZUKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Analysis of oncogene addiction and development of molecular-targeted therapy for small animal tumours
- Principal Investigator
  
  BONKOBARA Makoto
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Nippon Veterinary and Life Science University
Breaking immunological tolerance to canine malignant melanoma using anti-Gpnmb antibody and various antigen peptides associated with tumor.Principal Investigator
- Principal Investigator
  
  TOMIHARI Mizuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine
Breaking immunological tolerance to canine malignant melanoma by inhibition of Gpnmb expression : a new approach for melanoma immunotherapyPrincipal Investigator
- Principal Investigator
  
  TOMIHARI Mizuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Clinical veterinary science
- Research Institution
  Obihiro University of Agriculture and Veterinary Medicine

All 2017 2016 2015 2013 2010 2009 Other

All Journal Article Presentation

[Journal Article] Gene and protein expression of a soluble form of CTLA-4 in a healthy dog2017
- Author(s)
  Michihito Tagawa, Yuhei Yamamoto, Genya Shimbo, Aiko Iguchi, Xuenan Xuan, Mizuki Tomihari, Kazuro Miyahara
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 79 Issue: 5 Pages: 871-875
- DOI
  10.1292/jvms.16-0583
- NAID
  130007331474
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18788, KAKENHI-PROJECT-15K07736
[Journal Article] Influence of transfusion of lymphokine-activated T killer cells on inflammatory responses in dogs after laparotomy2016
- Author(s)
  Mie K, Tomihari M, Hoshi K, Nakamura T, Yamaguchi T, Miyahara K, Shimada T.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 78 Issue: 4 Pages: 579-585
- DOI
  10.1292/jvms.15-0626
- NAID
  130007331497
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07736
[Journal Article] A comparison of the immunological effects of propofol and isoflurane for maintenance of anesthesia in healthy dogs2015
- Author(s)
  Tomihari M, Nishihara A, Shimada T, Yanagawa M, Miyoshi M, Miyahara K, Oishi A.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 77 Issue: 10 Pages: 1227-1233
- DOI
  10.1292/jvms.14-0611
- NAID
  130005107584
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25850204
[Journal Article] The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease.2013
- Author(s)
  Chung JS, Tomihari M, Tamura K, Kojima T, Cruz PD Jr., Ariizumi K.
- Journal Title
  
  Immunology
  
  Volume: 138(2) Pages: 173-82
- Data Source
  KAKENHI-PROJECT-23780317
[Journal Article] The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease.2013
- Author(s)
  Chung JS, Tomihari M, Tamura K, Kojima T, Cruz PD Jr, Ariizumi K
- Journal Title
  
  Immunology.
  
  Volume: 138(2) Issue: 2 Pages: 173-182
- DOI
  10.1111/imm.12027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23780317, KAKENHI-PROJECT-24380173
[Journal Article] Depleting syndecan-4+ T lymphooytes usingt toxin-bearing dendritic cell-associated heparan suifate protenglycan-depedent integrin ligand:a new opportunity for treating activated T cell-driven disease.2010
- Author(s)
  Akiyoshi H, Chung JS, Tomihari M, ほか2名
- Journal Title
  
  J Immunol.
  
  Volume: 184(7) Pages: 3554-3561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] Depleting syndecan-4+ T lymphocytes using toxin-bearing dendritic cell-associated heparan sulfate proteoglycan-dependent integrin ligand : a new opportunity for treating activated T cell-driven disease.2010
- Author(s)
  Akiyoshi H, Chung JS, Tomihari M, Cruz PD, Jr, Ariizumi K.
- Journal Title
  
  J Immunol. 184(7)
  
  Pages: 3554-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells.2010
- Author(s)
  Tomihari M, ほか4名
- Journal Title
  
  Cancer Res.
  
  Volume: 70(14) Pages: 5778-5787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] DC-HIL/glycoprotein Nmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells.2010
- Author(s)
  Tomihari M, Chung JS, Akiyoshi H, Cruz PD, Jr, Ariizumi K.
- Journal Title
  
  Cancer Res. 70(14)
  
  Pages: 5778-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell responses.2009
- Author(s)
  Chung JS, Bonkobara M, Tomihari M, Cruz PD, Jr, Ariizumi K.
- Journal Title
  
  Eur J Immunol. 39(4)
  
  Pages: 965-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-denendent fashion.2009
- Author(s)
  Tomihari M, ほか4名
- Journal Title
  
  Exp Dermatol. 18(7)
  
  Pages: 586-595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function.2009
- Author(s)
  Chung JS, Yudate T, Tomihari M, Akiyoshi H, Cruz PD, Jr, Ariizumi K.
- Journal Title
  
  J Immunol. 183(8)
  
  Pages: 5190-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function.2009
- Author(s)
  Chung JS, Tomihari M, ほか4名
- Journal Title
  
  J Immunol. 183(8)
  
  Pages: 5190-5198
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] Gpnmb is a melanosome-associated glycoprotein that contributes to melanocyte/keratinocyte adhesion in a RGD-dependent fashion.2009
- Author(s)
  Tomihari M, Hwang SH, Chung JS, Cruz PD, Jr, Ariizumi K.
- Journal Title
  
  Exp Dermatol. 18(7)
  
  Pages: 586-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Journal Article] The DC-HIL/syndecan-4 pathway inhibits human allogeneic T-cell response.2009
- Author(s)
  Chung JS, Tomihari M, ほか3名
- Journal Title
  
  Eur J Immunol. 39(4)
  
  Pages: 965-974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21880008
[Presentation] 家族性発症を認めた犬の肥満細胞腫症例における遺伝学的検討2015
- Author(s)
  富張瑞樹
- Organizer
  平成26年度日本獣医師会獣医学術学会年次大会
- Place of Presentation
  岡山
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-25850204
[Presentation] 帯広畜産大学動物医療センターにおける活性化自己リンパ球療法の現状と問題点2013
- Author(s)
  富張瑞樹
- Organizer
  第2回動物臨床免疫療法研究会
- Place of Presentation
  大阪府立大学、りんくうキャンパス（大阪府泉佐野市りんくう往来北1番地の58）
- Invited
- Data Source
  KAKENHI-PROJECT-25850204
[Presentation] Syndecan-4 is an important negative regulator of T cell immunity and a potentially useful target for treating diseases resulting from such immunity.2010
- Author(s)
  Chung JS, Tomihari M, Akiyoshi H, Cruz PD, Jr, Ariizumi K
- Organizer
  Society for Investigative Dermatology, 70^<th> annual meeting
- Place of Presentation
  Atlanta, Georgia, USA
- Data Source
  KAKENHI-PROJECT-21880008
[Presentation] Exploiting the DC-HIL/syndecan-4 pathway to treat cutaneous T cell lymphoma.2009
- Author(s)
  Chung JS, Yudate T, Tomihari M, Cruz PD, Jr, Ariizumi K
- Organizer
  Society for Investigative Dermatology, 69^<th> annual meeting
- Place of Presentation
  Montreal, Canada, USA
- Data Source
  KAKENHI-PROJECT-21880008
[Presentation] Exploiting the DC-HIL/syndecan-4 pathway to treat cutaneous T cell lymphoma2009
- Author(s)
  Chung JS, Tomihari M, ほか4名
- Organizer
  Society for Investigative Dermatology, 69^<th> annual meeting
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-21880008
[Presentation] 活性化自己リンパ球療法を行った平滑筋肉腫の犬の１症例
- Author(s)
  ○富張瑞樹、東野　崇、三重慧一郎、三好雅史、宮原和郎、嶋田照雅
- Organizer
  平成23年度北海道獣医学術学会北海道地区学会・北海道獣医師大会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23780317

1. BONKOBARA Makoto (50343611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. TAZAKI Hiroyuki (80231405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. OMI Toshinori (40296091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. SHIMADA Takashi (20125074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MIZUNO TAKUYA (90398826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中川貴之 (40447363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tomihari Mizuki 富張 瑞樹

TOMIHARI Mizuki 富張 瑞樹

Research Projects

Research Products

Co-Researchers

Investigation of a new prediction model using genomic breeding values &#8203;&#8203;for canine hip dysplasiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research of new molecular target genes in canine mast cell tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the combined immune-modulatory therapies for canine cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of tumor-specific T cell therapy for canine melanoma cell lines.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of oncogene addiction and development of molecular-targeted therapy for small animal tumours

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Breaking immunological tolerance to canine malignant melanoma using anti-Gpnmb antibody and various antigen peptides associated with tumor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Breaking immunological tolerance to canine malignant melanoma by inhibition of Gpnmb expression : a new approach for melanoma immunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gene and protein expression of a soluble form of CTLA-4 in a healthy dog2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Influence of transfusion of lymphokine-activated T killer cells on inflammatory responses in dogs after laparotomy2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] A comparison of the immunological effects of propofol and isoflurane for maintenance of anesthesia in healthy dogs2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease.2013

Author(s)

Journal Title

Data Source

[Journal Article] The DC-HIL ligand syndecan-4 is a negative regulator of T-cell allo-reactivity responsible for graft-versus-host disease.2013

Author(s)

Journal Title

DOI

Data Source

Tomihari Mizuki 富張瑞樹

TOMIHARI Mizuki 富張瑞樹

Investigation of a new prediction model using genomic breeding values for canine hip dysplasiaPrincipal Investigator