ISHIMOTO Takatsugu 石本崇胤

Researcher Number	00594889
Other IDs
Affiliation (Current)	2025: 公益財団法人がん研究会, がん研究所発がん研究部, 部長 2025: 熊本大学, 国際先端医学研究機構, 客員教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 公益財団法人がん研究会, がん研究所発がん研究部, 部長 2023: 熊本大学, 国際先端医学研究機構, 客員教授 2023: 熊本大学, 病院, 特任教授 2019 – 2022: 熊本大学, 病院, 特任准教授 2017 – 2018: 熊本大学, 医学部附属病院, 特任准教授 … More 2016 – 2017: 熊本大学, 大学院生命科学研究部(医), 特任講師 2016: 熊本大学, 大学院生命科学研究部(医), 講師 2015 – 2016: 熊本大学, 国際先端医学研究機構, 准教授 2015: 熊本大学, 国際先端医学研究機構, 客員准教授 2015: 熊本大学, 学内共同利用施設等, 准教授 2015: 熊本大学, 国際先端医学研究拠点, 客員准教授 2015: 熊本大学, 大学院生命科学研究部, 特任助教 2014 – 2015: 熊本大学, 医学部附属病院, 非常勤診療医師 2013: 熊本大学, 消化器外科, 助教 2012 – 2013: 熊本大学, その他の研究科, 助教 2012 – 2013: 熊本大学, 大学院生命科学研究部, 助教 2012 – 2013: 熊本大学, 大学院生命科学研究部, 特任助教 Less
Review Section/Research Field	Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / General surgery / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / General surgery / Basic Section 55040:Respiratory surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator CAFs / 腫瘍間質 / 空間的遺伝子発現解析 / 胃がん / 癌幹細胞 / リプログラミング / 血行性転移 / 血小板 / ストローマ / 多様性 … More / 慢性炎症 / 胃癌 / CTC / ADC / オプトジェネティクス / 腫瘍線維化 / 循環腫瘍細胞 / シェアストレス / 間質 / シングルセル解析 / ニッチ / CTCクラスター / 腫瘍循環細胞 / 線維芽細胞 / CTCs / 血行性がん転移 / 細胞外小胞 / 細胞老化 / 抗PD-1抗体 / 腫瘍微小環境 / アラキドン酸カスケード / アラキドン酸 / 癌関連線維芽細胞 / 治療抵抗性 / 活性酸素 / 消化器癌 / microRNA / xCT / CD44 … More Except Principal Investigator CAFs / 胃癌 / 腫瘍微小環境 / 消化器癌 / 食道癌 / microRNA / 胃がん / FBXW7 / 腸内細菌叢 / 大腸癌 / microbiome / 腫瘍免疫 / 膵癌 / 乳酸 / LDHA / 生体イメージング / 2光子顕微鏡 / 抗癌剤感受性 / 腸内細菌 / Microbiome / 腫瘍間質 / サルコペニア / RNF43 / Hippo pathway / 癌幹細胞 / エピジェネティクス / 癌 / CD44 / 食道扁平上皮癌 / miR-21 / オープンクロマチン領域 / 単一核マルチオーム解析 / シングルセル解析 / エピゲノム / 線維化 / 遠隔臓器連関 / 血小板 / PDGF / LNP / 光学的リーサリティ / 細胞間相互作用 / シングルセルマルチオミクス / C-JUN N-terminal Kinase / 腫瘍関連線維芽細胞 / GAPPS / 代謝リモデリング / 大腸がん / 西洋型食生活 / コリバクチン産生大腸菌 / 遺伝子変異 / 膵管内乳頭粘液性腫瘍 / IPMN / Gnas / Rnf43 / 回路 / TCA / JAK-STAT阻害剤 / 細胞老化 / 腹膜播種 / EZH2 / 浸潤 / 自律神経 / C AFs / SGLT2阻害剤 / 消化管GIST / 細胞周期 / Glycolysis / GLUT1 / BAY-876 / GLUT1阻害剤 / GIST / 消化管癌 / 抗がん剤抵抗性 / Taz / Yap / TAZ / YAP / autophagy / Fusobacterium / 抗がん剤 / 化学療法 / Fusobacterium nucleatum / 抗癌剤 / sarcopenia / 栄養状態 / 炎症性発癌 / ストローマ細胞 / 繊維芽細胞 / 炎症 / 癌関連繊維芽細胞 / 癌関連線維芽細胞 / RAS 遺伝子変異 / アクチビン / アクチビン/ミオスタチン経路 / MSI status / 腫瘍局所免疫 / Activin A / 骨格筋量 / Activin/Myostatin経路 / カヘキシア / Wnt シグナル / RNF43遺伝子 / Wntシグナル / predictive marker / immunity / cancer metabolism / epigenetic change / genetic change / がん代謝 / バイオマーカー / CCN family / C5aR / C5a / 肝stellate cell / 大腸癌肝転移 / 肝星細胞 / C5a受容体 / 補体C5a / PTEN / cisplatine / Trastuzumab / HER2 / c-Jun / c-Myc / MCL1 / miR 223 / 薬剤耐性 / トラスツズマブ / Bmi-1 / 循環微量癌細胞 / ニッチ / EGFR / SPINK1 / PSTI / 正常胃粘膜 / 膵分泌性トリプシンインヒビター / microRNA array / マイクロアレイ / CGH array / Trastuzumab耐性 / トラスツズマブ耐性 / lncRNA / lincRNA / 血清 / 組織 / real-time PCR / non-coding RNA / pyrosequence / 予後因子 / メチル化 / IGF2 DMR0 / トランスレーショナルリサーチ / RNP2 / exosome / miR-328 / TAM / Bmi1 / DCF療法 / がん幹細胞 / miR-223 / miR-30e* / マイクロＲＮＡ / 治療感受性 / 術前化学療法 / microRNA-21 / microRNA-223 / Ribophorin II / mircoRNA / 個別化治療 / 化学療法感受性 / miRNA / replacement therapy / mTOR Less

遺伝性胃癌臨床検体を用いた上部胃癌発癌メカニズムの解明と革新的治療法の確立
- Principal Investigator
  
  岩槻政晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
オプトジェネティクス技術を用いた腫瘍微小環境制御の可能性を拓くPrincipal Investigator
- Principal Investigator
  
  石本崇胤
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Japanese Foundation for Cancer Research
ストローマル・リプログラミングを軸としたがん治療戦略の開発Principal Investigator
- Principal Investigator
  
  石本崇胤
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Fund for the Promotion of Joint International Research (International Collaborative Research)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Japanese Foundation for Cancer Research
腫瘍間質に依存したシェアストレス抵抗性の獲得と血行性がん転移機構の解明Principal Investigator
- Principal Investigator
  
  石本崇胤
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
JNKシグナル制御による免疫抑制的腫瘍微小環境の克服
- Principal Investigator
  
  千場隆
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
光学的リーサリティを用いた腫瘍間質リモデリング効果の生体イメージング
- Principal Investigator
  
  福田正裕
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
遠隔臓器コミュニケーションによるスキルス胃癌線維化メカニズムの解明
- Principal Investigator
  
  安田忠仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
単一核マルチオーム解析を用いた胃がん間質不均一性の解明
- Principal Investigator
  
  内原智幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
がんーストローマ代謝物クロストークによる膵癌進展メカニズムの解明
- Principal Investigator
  
  北村文優
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Elucidation the mechanism between western diet and carcinogenesis via gut microbiome
- Principal Investigator
  
  Arima Kota
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Elucidation of circulating cluster niche for hematogenous metastasisPrincipal Investigator
- Principal Investigator
  
  Ishimoto Takatsugu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kumamoto University
Elucidation of diversity and therapeutic target in scirrhous gastric cancer stromaPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Takatsugu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kumamoto University
Application of bioimaging technique for the investigation of mechanisms of metastasis depending on tumor stroma.
- Principal Investigator
  
  Fukuda Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Identification of molecular mechanism underlying peritoneal metastasis progression by tumor stromal cells.
- Principal Investigator
  
  Yasuda Tadahito
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Elucidation of pancreatic carcinogenesis mechanism via WNT signaling by RNF43 gene abnormalities
- Principal Investigator
  
  Sugihara Hidetaka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Development of anti-stromal therapeutic strategy based on histological molecular subtyping of gastric cancer stroma.Principal Investigator
- Principal Investigator
  
  Ishimoto Takatsugu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
Biological roles of dysregulated Hippo pathway on cancer stem like function during the tumor progression of gastroenterological cancers
- Principal Investigator
  
  Hayashi Hiromitsu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Investigation of the treatment for gastrointestinal cancers and gastrointestinal stromal tumors using the glucose transporter 1 inhibitor.
- Principal Investigator
  
  Sawayama Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Kumamoto University
Identification of molecular mechanism underlying inflammatory-related carcinogenesis through activating the stroma in gastric cancer
- Principal Investigator
  
  Miyake Keisuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Comprehensive analysis of gut microbiome and sarcopenia in gastrointestinal cancers
- Principal Investigator
  
  Baba Hideo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kumamoto University
Fusobacterium nucleatum Confers Chemoresistance by Modulating Autophagy in Esophageal Squamous Cell Carcinoma
- Principal Investigator
  
  BABA Hideo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kumamoto University
Investigation of CCN family for development and drug resistance of gastrointestinal cancers
- Principal Investigator
  
  Nagai Youhei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
To identify the molecular mechanism underlying colorectal cancer progression via RNF43
- Principal Investigator
  
  Hdetaka Sugihara
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Comprehensive analysis of cancer cachexia signaling pathway for identifying a new therapeutic strategy in colorectal cancer.
- Principal Investigator
  
  Miyamoto Yuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Identification of the novel niche factor implicated in cancer stem cell maintenance in tumor stroma.Principal Investigator
- Principal Investigator
  
  ISHIMOTO Takatsugu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
establishment of cancer treatment targeting C5a receptor and proteinase releaed by cancer cells
- Principal Investigator
  
  NITTA Hidetoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Identification of the molecular mechanism underlying cancer stem cell regulation via arachidonic cascadePrincipal Investigator
- Principal Investigator
  
  ISHIMOTO Takatsugu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
The identification of novel microRNAs regulating cancer stem cell properties and the clinical application to therapeutic strategy in gastrointestinal cancer
- Principal Investigator
  
  BABA Hideo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
Clarification of the microRNA pathway regulating resistance to Trastuzumab in gastric cancer
- Principal Investigator
  
  HAYASHI Naoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Comprehensive analysis of expression and function of lincRNA in gastroenterological cancer
- Principal Investigator
  
  Hiyoshi Yukiharu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Japanese Foundation for Cancer Research
  Kumamoto University
  Kyushu University
The Molecular mechanism of trastuzumab for gastric cancer via microRNA –gene pathway
- Principal Investigator
  
  IWATSUKI Masaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Function analysis of SPINK1 in normal gastric mucosa epithelium and gastric cancer
- Principal Investigator
  
  OZAKI Nobuyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University
Regulation of Mammalian Target of Rapamycin (mTOR) Signaling by MicroRNA in esophageal cancer
- Principal Investigator
  
  KINOSHITA Kouichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
The identification of functional role of CD44 in redox status and the application to therapeutic strategy in cancerPrincipal Investigator
- Principal Investigator
  
  ISHIMOTO takatsugu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kumamoto University
Individualized treatment strategy for esophageal cancer based on the expression of microRNAs in preoperative biopsy specimens.
- Principal Investigator
  
  Msayuki Watanabe
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Japanese Foundation for Cancer Research
  Kumamoto University
Comprehensive analysis of IGF2 DMR0 methylation level in esophageal cancer
- Principal Investigator
  
  BABA Yoshifumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Kumamoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment2024
- Author(s)
  Yonemura A、Semba T、Zhang J、Fan Y、Yasuda-Yoshihara N、Wang H、Uchihara T、Yasuda T、Nishimura A、Fu L、Hu X、Wei F、Kitamura F、Akiyama T、Yamashita K、Eto K、Iwagami S、Iwatsuki M、Miyamoto Y、Matsusaki K、Yamasaki J、Nagano O、Saya H、Song S、Tan P、Baba H、Ajani Jaffer A.、Ishimoto T
- Journal Title
  
  Cell Reports
  
  Volume: 43 Issue: 1 Pages: 113613-113613
- DOI
  10.1016/j.celrep.2023.113613
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14572, KAKENHI-PROJECT-23K14621, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-23K08113, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23H00410, KAKENHI-PROJECT-23K27689
[Journal Article] RAC1-mediated integrin alpha-6 expression in E-cadherin-deficient gastric cancer cells promotes interactions with the stroma and peritoneal dissemination2024
- Author(s)
  Zhang Jun、Fu Lingfeng、Wang Huaitao、Yonemura Atsuko、Semba Takashi、Yasuda-Yoshihara Noriko、Nishimura Akiho、Tajiri Takuya、Tong Yilin、Yasuda Tadahito、Uchihara Tomoyuki、Yamazaki Masaya、Okamoto Yuya、Yamasaki Juntaro、Nagano Osamu、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Cancer Letters
  
  Volume: 591 Pages: 216901-216901
- DOI
  10.1016/j.canlet.2024.216901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14572, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27689
[Journal Article] Body Composition and Clinical Outcomes in Esophageal Cancer Patients Treated with Immune Checkpoint Inhibitors2024
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Hara Yoshihiro、Wang Haolin、Nomoto Daichi、Toihata Tasuku、Ohuchi Mayuko、Harada Kazuto、Eto Kojiro、Ogawa Katsuhiro、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: Published online Issue: 6 Pages: 3839-3849
- DOI
  10.1245/s10434-024-15093-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08687, KAKENHI-PROJECT-21KK0153
[Journal Article] Downregulation of 15-PGDH enhances MASH-HCC development via fatty acid-induced T-cell exhaustion2023
- Author(s)
  Hu X、Yasuda T、Yasuda-Yosihara N、Yonemura A、Umemoto T、Nakachi Y、Yamashita K、Semba T、Arima K、Uchihara T、Nishimura A、Bu L、Fu Li、Wei F、Zhang J、Tong Y、Wang H、Iwamoto K、Fukuda T、Nakagawa H、Taniguchi K、Miyamoto Y、Baba H、Ishimoto T
- Journal Title
  
  JHEP Reports
  
  Volume: 5 Issue: 12 Pages: 100892-100892
- DOI
  10.1016/j.jhepr.2023.100892
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21K08686, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03758, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K27463, KAKENHI-PROJECT-23K27669
[Journal Article] Intratumour Fusobacterium nucleatum and immune response to oesophageal cancer2023
- Author(s)
  Kosumi Keisuke、Baba Yoshifumi、Yamamura Kensuke、Nomoto Daichi、Okadome Kazuo、Yagi Taisuke、Toihata Tasuku、Kiyozumi Yuki、Harada Kazuto、Eto Kojiro、Sawayama Hiroshi、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  British Journal of Cancer
  
  Volume: 128 Issue: 6 Pages: 1155-1165
- DOI
  10.1038/s41416-022-02112-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08687, KAKENHI-PROJECT-20H03755, KAKENHI-PROJECT-21K16452, KAKENHI-PROJECT-23K24408, KAKENHI-PROJECT-23K15435, KAKENHI-PROJECT-22K08851, KAKENHI-PROJECT-21KK0153
[Journal Article] LINE-1 hypomethylation, increased retrotransposition and tumor-specific insertion in upper gastrointestinal cancer2023
- Author(s)
  Baba Y, Yasuda N, Bundo M, Nakachi Y, Ueda J, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Oshiumi H, Iwamoto K, Baba H.
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 1 Pages: 247-256
- DOI
  10.1111/cas.16007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27640
[Journal Article] IL-1β derived from mixed-polarized macrophages activates fibroblasts and synergistically forms a cancer-promoting microenvironment2023
- Author(s)
  Zhang Jun、Fu Lingfeng、Yasuda-Yoshihara Noriko、Yonemura Atsuko、Wei Feng、Bu Luke、Hu Xichen、Akiyama Takahiko、Kitamura Fumimasa、Yasuda Tadahito、Semba Takashi、Uchihara Tomoyuki、Itoyama Rumi、Yamashita Kohei、Eto Kojiro、Iwagami Shiro、Yashiro Masakazu、Komohara Yoshihiro、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Gastric Cancer
  
  Volume: 26 Issue: 2 Pages: 187-202
- DOI
  10.1007/s10120-022-01352-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
[Journal Article] Cancer-associated fibroblasts reuse cancer-derived lactate to maintain a fibrotic and immunosuppressive microenvironment in pancreatic cancer2023
- Author(s)
  Kitamura F、Semba T、Yasuda-Yoshihara N、Yamada K、Nishimura A、Yamasaki J、Nagano O、Yasuda T、Yonemura A、Tong Y、Wang H、Akiyama T、Matsumura K、Uemura N、Itoyama R、Bu L、Fu L、Hu X、Wei F、Mima K、Imai K、Hayashi H、Yamashita Y、Miyamoto Y、Baba H、Ishimoto T
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 20
- DOI
  10.1172/jci.insight.163022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14572, KAKENHI-PROJECT-23K14621, KAKENHI-PROJECT-22K08756, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-22K16537, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463, KAKENHI-PROJECT-23K27689
[Journal Article] Cellular senescence in the tumor microenvironment and context‐specific cancer treatment strategies2023
- Author(s)
  Yasuda Tadahito、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 5 Pages: 1290-1302
- DOI
  10.1111/febs.16231
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-23K08051
[Journal Article] Cellular senescence induction leads to progressive cell death via the INK4a‐RB pathway in naked?mole‐rats2023
- Author(s)
  Kawamura Y, Oka K, Semba T, Takamori M, Sugiura Y, Yamasaki R, Suzuki Y, Chujo T, Nagase M, Oiwa Y, Fujioka S, Homma S, Yamamura Y, Miyawaki S, Narita M, Fukuda T, Sakai Y, Ishimoto T, Tomizawa K, Suematsu M, Yamamoto T, Bono H, Okano H, Miura K
- Journal Title
  
  The EMBO Journal
  
  Volume: 42 Issue: 16
- DOI
  10.15252/embj.2022111133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-22H04925
[Journal Article] A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts2023
- Author(s)
  Wei F , Uchihara T , Yonemura A , Yasuda-Yoshihara N , Yasuda T , Semba T , Fukuda M , Akiyama T , Kitamura F , Kariya R , Yamasaki J , Aihara K , Yamashita K , Nagano O , Okada S , Baba H , Ishimoto T
- Journal Title
  
  The FEBS Journal
  
  Volume: - Issue: 10 Pages: 2604-2615
- DOI
  10.1111/febs.16712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-20K08961, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-23K14621, KAKENHI-PROJECT-23K06745, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
[Journal Article] Tumor microenvironmental 15‐PGDH depletion promotes fibrotic tumor formation and angiogenesis in pancreatic cancer2022
- Author(s)
  Bu L, Yonemura A, Yasuda-Yoshihara N, Uchihara T, Ismagulov G, Takasugi S, Yasuda T, Okamoto Y, Kitamura F, Akiyama T, Arima K, Itoyama R, Zhang J, Fu L, Hu X, Wei, F, Arima Y, Moroishi T, Nishiyama K, Sheng G, Mukunoki T, Otani J, Baba H, Ishimoto T
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3579-3592
- DOI
  10.1111/cas.15495
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21H02490, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535
[Journal Article] Detection of senescent cells in malignant ascites using mass cytometry and therapeutic strategies focused on cellular senescence2022
- Author(s)
  安田忠仁、石本崇胤
- Journal Title
  
  Cytometry Research
  
  Volume: 32 Issue: 1 Pages: 27-32
- DOI
  10.18947/cytometryresearch.32.1_27
- ISSN
  0916-6920, 2424-0664
- Year and Date
  2022-07-13
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08985
[Journal Article] Intracellular MUC20 variant 2 maintains mitochondrial calcium homeostasis and enhances drug resistance in gastric cancer2022
- Author(s)
  Fu Lingfeng、Yonemura Atsuko、Yasuda-Yoshihara Noriko、Umemoto Terumasa、Zhang Jun、Yasuda Tadahito、Uchihara Tomoyuki、Akiyama Takahiko、Kitamura Fumimasa、Yamashita Kohei、Okamoto Yuya、Bu Luke、Wei Feng、Hu Xichen、Liu Yang、Ajani Jaffer A.、Tan Patrick、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Gastric Cancer
  
  Volume: 25 Issue: 3 Pages: 542-557
- DOI
  10.1007/s10120-022-01283-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03688, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535
[Journal Article] Gut microbiome in gastrointestinal cancer: a friend or foe?2022
- Author(s)
  Liu Y, Baba Y, Ishimoto T, Gu X, Zhang J, Nomoto D, Okadome K, Baba H, Qiu P
- Journal Title
  
  International Journal of Biological Sciences
  
  Volume: 18 Issue: 10 Pages: 4101-4117
- DOI
  10.7150/ijbs.69331
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20H03755, KAKENHI-PROJECT-23K24408
[Journal Article] The Gut Microbiota in Inflammatory Bowel Disease2022
- Author(s)
  Qiu P, Ishimoto T, Fu L, Zhang J, Zhang Z, Liu Y
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 12
- DOI
  10.3389/fcimb.2022.733992
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531
[Journal Article] Single-Cell Atlas of Lineage States, Tumor Microenvironment, and Subtype-Specific Expression Programs in Gastric Cancer2022
- Author(s)
  Kumar V, Ramnarayanan K, Sundar R, Padmanbahan N, Srivastava S, Koiwa M, Yasuda T, Koh V, Huang K, Tay S, Ho S, Tan A, Ishimoto T
- Journal Title
  
  Cancer Discovery
  
  Volume: 12 Issue: 3 Pages: 670-691
- DOI
  10.1158/2159-8290.cd-21-0683
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535
[Journal Article] MEK inhibition suppresses metastatic progression of <i>KRAS</i> ‐mutated gastric cancer2022
- Author(s)
  Yamasaki Juntaro、Hirata Yuki、Otsuki Yuji、Suina Kentaro、Saito Yoshiyuki、Masuda Kenta、Okazaki Shogo、Ishimoto Takatsugu、Saya Hideyuki、Nagano Osamu
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 3 Pages: 916-925
- DOI
  10.1111/cas.15244
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16315, KAKENHI-PROJECT-21H02766, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-21K19417, KAKENHI-PROJECT-20K18174, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535
[Journal Article] Stromal reprogramming through dual PDGFRα/β blockade boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors.2022
- Author(s)
  T. Akiyama, T. Yasuda, T. Uchihara, N. Yasuda-Yoshihara, BJY. Tan, A. Yonemura, T. Semba, J. Yamasaki, Y. Komohara, K. Ohnishi, F. Wei, L. Fu, J. Zhang, F. Kitamura, K. Yamashita, K. Eto, S. Iwagami, H. Tsukamoto, T. Umemoto, M. Masuda, O. Nagano, Y. Satou, H. Saya, P. Tan, H. Baba, T. Ishimoto
- Journal Title
  
  Cancer Res.
  
  Volume: 83 Issue: 5 Pages: 753-770
- DOI
  10.1158/0008-5472.can-22-1890
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07370, KAKENHI-PROJECT-22K20836, KAKENHI-PROJECT-20H00518, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21H02788, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-23K08051, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-23K27463
[Journal Article] Conflicting metabolic alterations in cancer stem cells and regulation by the stromal niche2021
- Author(s)
  Yasuda T, I Ishimoto T, Baba H
- Journal Title
  
  Regenerative Therapy
  
  Volume: 17 Pages: 8-12
- DOI
  10.1016/j.reth.2021.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
[Journal Article] Protocol to establish cancer-associated fibroblasts from surgically resected tissues and generate senescent fibroblasts2021
- Author(s)
  Yasuda T, Koiwa M, Yonemura A, Akiyama T, Baba H, Ishimoto T
- Journal Title
  
  STAR Protocols
  
  Volume: 2 Issue: 2 Pages: 100553-100553
- DOI
  10.1016/j.xpro.2021.100553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
[Journal Article] Assessment of the Diagnostic Efficiency of a Liquid Biopsy Assay for Early Detection of Gastric Cancer2021
- Author(s)
  Izumi D, Zhu Z, Chen Y, Toden S, Huo X, Kanda M, Ishimoto T, Gu D, Tan M, Kodera Y, Baba H, Li W, Chen J, Wang X, Goel A
- Journal Title
  
  JAMA Network Open
  
  Volume: 4 Issue: 8 Pages: 2121129-2121129
- DOI
  10.1001/jamanetworkopen.2021.21129
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21KK0153
[Journal Article] Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination2021
- Author(s)
  Yasuda T, Koiwa M, Yonemura A, Miyake K, Kariya R, Kubota S, Yokomizo-Nakano T, Yasuda-Yoshihara N, Uchihara T, Itoyama R, Bu L, Fu L, Arima K, Izumi D, Iwagami S, Eto K, Iwatsuki M, Baba Y, Yoshida N, Ohguchi H, Okada S, Matsusaki K, Sashida G, Takahashi A, Tan P, Baba H, Ishimoto T.
- Journal Title
  
  Cell Reports
  
  Volume: 34 Issue: 8 Pages: 108779-108779
- DOI
  10.1016/j.celrep.2021.108779
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16749, KAKENHI-PROJECT-19H03507, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21K16384, KAKENHI-PROJECT-21KK0153
[Journal Article] Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer2021
- Author(s)
  Itoyama R, Yasuda-Yoshihara N, Kitamura F, Yasuda T, Bu L, Yonemura A, Uchihara T, Arima K, Hu X, Jun Z, Okamoto Y, Akiyama T, Yamashita K, Nakao Y, Yusa T, Kitano Y, Higashi T, Miyata T, Imai K, Hayashi H, Yamashita Y, Mikawa T, Kondoh H, Baba H, Ishimoto T
- Journal Title
  
  Cancer Letters
  
  Volume: 523 Pages: 29-42
- DOI
  10.1016/j.canlet.2021.09.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07887, KAKENHI-PROJECT-20K16418, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-20K09038, KAKENHI-PROJECT-21K19535, KAKENHI-PROJECT-21K16384, KAKENHI-PROJECT-21KK0153, KAKENHI-PROJECT-20K20658
[Journal Article] Gastric Cancer Stem Cells: Current Insights into the Immune Microenvironment and Therapeutic Targets2020
- Author(s)
  Fu L, Bu L, Yasuda T, Koiwa M, Akiyama T, Uchihara T, Baba H, Ishimoto T
- Journal Title
  
  Biomedicines
  
  Volume: 8 Issue: 1 Pages: 7-7
- DOI
  10.3390/biomedicines8010007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03531
[Journal Article] Extracellular Vesicles from Cancer-Associated Fibroblasts Containing Annexin A6 Induces FAK-YAP Activation by Stabilizing β1 Integrin, Enhancing Drug Resistance2020
- Author(s)
  Uchihara T, Miyake K, Yonemura A, Komohara Y, Itoyama R, Koiwa M, Yasuda T, Arima K, Harada K, Eto K, Hayashi H, Iwatsuki M, Iwagami S, Baba Y, Yoshida N, Yashiro M, Masuda M, Ajani Jaffer A, Tan Patrick, Baba H, Ishimoto T
- Journal Title
  
  Cancer Research
  
  Volume: 80 Issue: 16 Pages: 3222-3235
- DOI
  10.1158/0008-5472.can-19-3803
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09177, KAKENHI-PROJECT-20K07690, KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-20H03531, KAKENHI-PROJECT-18K08543, KAKENHI-PROJECT-19K16720, KAKENHI-PROJECT-19K16749, KAKENHI-PROJECT-18H02883
[Journal Article] Mucosal cancer-associated microbes and anastomotic leakage after resection of colorectal carcinoma2020
- Author(s)
  Mima Kosuke、Sakamoto Yuki、Kosumi Keisuke、Ogata Yoko、Miyake Keisuke、Hiyoshi Yukiharu、Ishimoto Takatsugu、Iwatsuki Masaaki、Baba Yoshifumi、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Ogino Shuji、Baba Hideo
- Journal Title
  
  Surgical Oncology
  
  Volume: 32 Pages: 63-68
- DOI
  10.1016/j.suronc.2019.11.005
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-18H02694, KAKENHI-PROJECT-17H05094, KAKENHI-PROJECT-18K19586
[Journal Article] Functional diversity of cancer‐associated fibroblasts in modulating drug resistance2020
- Author(s)
  Bu Luke、Baba Hideo、Yasuda Tadahito、Uchihara Tomoyuki、Ishimoto Takatsugu
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 10 Pages: 3468-3477
- DOI
  10.1111/cas.14578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08985, KAKENHI-PROJECT-20H03531
[Journal Article] Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma.2020
- Author(s)
  Liu Y, Baba Y, Ishimoto T, Tsutsuki H, Zhang T, Nomoto D, Okadome K, Yamamura K, Harada K, Eto K, Hiyoshi Y, Iwatsuki M, Nagai Y, Iwagami S, Miyamoto Y, Yoshida N, Komohara Y, Ohmuraya M, Wang X, Ajani JA, Sawa T, Baba H.
- Journal Title
  
  Br J Cancer.
  
  Volume: 124 Issue: 5 Pages: 963-974
- DOI
  10.1038/s41416-020-01198-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08405, KAKENHI-PROJECT-18H02694
[Journal Article] Prognostic and clinical impact of PD-L2 and PD-L1 expression in a cohort of 437 oesophageal cancers2020
- Author(s)
  Okadome Kazuo、Baba Yoshifumi、Nomoto Daichi、Yagi Taisuke、Kalikawe Rebecca、Harada Kazuto、Hiyoshi Yukiharu、Nagai Yohei、Ishimoto Takatsugu、Iwatsuki Masaaki、Iwagami Shiro、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Komohara Yoshihiro、Shono Takashi、Sasaki Yutaka、Baba Hideo
- Journal Title
  
  British Journal of Cancer
  
  Volume: - Issue: 10 Pages: 1535-1543
- DOI
  10.1038/s41416-020-0811-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-19K17437, KAKENHI-PROJECT-19K18094
[Journal Article] Effect of Resection of the Thoracic Duct and Surrounding Lymph Nodes on Short- and Long-Term and Nutritional Outcomes After Esophagectomy for Esophageal Cancer2019
- Author(s)
  Yoshida Naoya、Nagai Yohei、Baba Yoshifumi、Miyamoto Yuji、Iwagami Shiro、Iwatsuki Masaaki、Hiyoshi Yukiharu、Eto Kojiro、Ishimoto Takatsugu、Kiyozumi Yuki、Nomoto Daichi、Akiyama Takahiko、Imamura Yu、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 26 Issue: 6 Pages: 1893-1900
- DOI
  10.1245/s10434-019-07304-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596
[Journal Article] Morphological lymphocytic reaction, patient prognosis and?PD‐1 expression after surgical resection for oesophageal cancer2019
- Author(s)
  Baba Y.、Yagi T.、Kosumi K.、Okadome K.、Nomoto D.、Eto K.、Hiyoshi Y.、Nagai Y.、Ishimoto T.、Iwatsuki M.、Iwagami S.、Miyamoto Y.、Yoshida N.、Komohara Y.、Watanabe M.、Baba H.
- Journal Title
  
  BJS
  
  Volume: 106 Issue: 10 Pages: 1352-1361
- DOI
  10.1002/bjs.11301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16750, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K10596
[Journal Article] Conophylline suppresses pancreatic cancer desmoplasia and cancer-promoting cytokines produced by cancer-associated fibroblasts2019
- Author(s)
  N. Ishii, K. Araki, T. Yokobori, K. Hagiwara, G. Dolgormaa, T. Yamanaka, T. Handa, M. Tsukagoshi, T. Igarashi, A. Watanabe, N. Kubo, N. Harimoto, A. Masamune, K. Umezawa, H. Kuwano, K. Shirabe
- Journal Title
  
  Cancer Science
  
  Volume: 10 Issue: 1 Pages: 334-434
- DOI
  10.1111/cas.13874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01967, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-17K10704
[Journal Article] Glucose transporter 1 regulates the proliferation and cisplatin sensitivity of esophageal cancer2019
- Author(s)
  Sawayama Hiroshi、Ogata Yoko、Ishimoto Takatsugu、Mima Kosuke、Hiyoshi Yukiharu、Iwatsuki Masaaki、Baba Yoshifumi、Miyamoto Yuji、Yoshida Naoya、Baba Hideo
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 5 Pages: 1705-1714
- DOI
  10.1111/cas.13995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09199
[Journal Article] Biological heterogeneity and versatility of cancer-associated fibroblasts in the tumor microenvironment.2019
- Author(s)
  Bu L, Baba H, Yoshida N, Miyake K, Yasuda T, Uchihara T, Tan P, Ishimoto T
- Journal Title
  
  Oncogene
  
  Volume: 38 Pages: 4887-4901
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08543
[Journal Article] Nrf2 promotes oesophageal cancer cell proliferation via metabolic reprogramming and detoxification of reactive oxygen species.2018
- Author(s)
  Kitano Y, Baba Y, Nakagawa S, Miyake K, Iwatsuki M, Ishimoto T, Yamashita YI, Yoshida N, Watanabe M, Nakao M, Baba H.
- Journal Title
  
  J Pathol.
  
  Volume: 244(3) Issue: 3 Pages: 346-357
- DOI
  10.1002/path.5021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-18K16370
[Journal Article] Progress in characterizing the linkage between Fusobacterium nucleatum and gastrointestinal cancer2018
- Author(s)
  Liu Yang、Baba Yoshifumi、Ishimoto Takatsugu、Iwatsuki Masaaki、Hiyoshi Yukiharu、Miyamoto Yuji、Yoshida Naoya、Wu Rong、Baba Hideo
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 54 Issue: 1 Pages: 33-41
- DOI
  10.1007/s00535-018-1512-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19586, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-17K19702, KAKENHI-PROJECT-19K18094, KAKENHI-PROJECT-18H02694
[Journal Article] Prognostic Factors of Salvage Esophagectomy for Residual or Recurrent Esophageal Squamous Cell Carcinoma After Definitive Chemoradiotherapy.2018
- Author(s)
  Kiyozumi Y, Yoshida N, Ishimoto T, Yagi T, Koga Y, Uchihara T, Sawayama H, Hiyoshi Y, Iwatsuki M, Baba Y, Miyamoto Y, Watanabe M, Matsuyama T, Oya N, Baba H.
- Journal Title
  
  World J Surg.
  
  Volume: Feb 8. Issue: 9 Pages: 2887-2893
- DOI
  10.1007/s00268-018-4536-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-16K19942
[Journal Article] Long Interspersed Element-1 Methylation Level as a Prognostic Biomarker in Gastrointestinal Cancers.2018
- Author(s)
  Baba Y, Yagi T, Sawayama H, Hiyoshi Y, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Baba H.
- Journal Title
  
  Digestion.
  
  Volume: 97(1) Issue: 1 Pages: 26-30
- DOI
  10.1159/000484104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-16K19942
[Journal Article] Clinical Importance of Mean Corpuscular Volume as a Prognostic Marker After Esophagectomy for Esophageal Cancer2018
- Author(s)
  Yoshida Naoya、Kosumi Keisuke、Tokunaga Ryuma、Baba Yoshifumi、Nagai Yohei、Miyamoto Yuji、Iwagami Shiro、Iwatsuki Masaaki、Hiyoshi Yukiharu、Ishimoto Takatsugu、Eto Kojiro、Imamura Yu、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Volume: 271 Issue: 3 Pages: 1-1
- DOI
  10.1097/sla.0000000000002971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-19K09076
[Journal Article] IDO1 Expression Is Associated With Immune Tolerance and Poor Prognosis in Patients With Surgically Resected Esophageal Cancer.2018
- Author(s)
  Kiyozumi Y, Baba Y, Okadome K, Yagi T, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Watanabe M, Komohara Y, Baba H.
- Journal Title
  
  Ann Surg
  
  Volume: Mar 27 Issue: 6 Pages: 1-1
- DOI
  10.1097/sla.0000000000002754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19702, KAKENHI-PROJECT-18K19586, KAKENHI-PROJECT-17KK0195, KAKENHI-PROJECT-17H04273
[Journal Article] Prognostic Nutritional Index, Tumor-infiltrating Lymphocytes, and Prognosis in Patients with Esophageal Cancer2018
- Author(s)
  Okadome Kazuo、Baba Yoshifumi、Yagi Taisuke、Kiyozumi Yuki、Ishimoto Takatsugu、Iwatsuki Masaaki、Miyamoto Yuji、Yoshida Naoya、Watanabe Masayuki、Baba Hideo
- Journal Title
  
  Annals of Surgery
  
  Volume: 271 Issue: 4 Pages: 1-1
- DOI
  10.1097/sla.0000000000002985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KK0195, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-17K19702, KAKENHI-PROJECT-18K19586
[Journal Article] Downregulation of 15-hydroxyprostaglandin dehydrogenase by interleukin-1β from activated macrophages leads to poor prognosis in pancreatic cancer.2018
- Author(s)
  Arima K, Komohara Y, Bu L, Tsukamoto M, Itoyama R, Miyake K, Uchihara T, Ogata Y, Nakagawa S, Okabe H, Imai K, Hashimoto D, Chikamoto A, Yamashita YI, Baba H, Ishimoto T
- Journal Title
  
  Cancer Sci
  
  Volume: 109(2) Issue: 2 Pages: 462-470
- DOI
  10.1111/cas.13467
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19936, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K15595
[Journal Article] Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas2018
- Author(s)
  Arima Kota、Ohmuraya Masaki、Miyake Keisuke、Koiwa Mayu、Uchihara Tomoyuki、Izumi Daisuke、Gao Feng、Yonemura Atsuko、Bu Luke、Okabe Hirohisa、Imai Katsunori、Hashimoto Daisuke、Baba Yoshifumi、Chikamoto Akira、Yamashita Yo-ichi、Furukawa Toru、Araki Kimi、Baba Hideo、Ishimoto Takatsugu
- Journal Title
  
  Oncogene
  
  Volume: 38 Issue: 8 Pages: 1211-1224
- DOI
  10.1038/s41388-018-0510-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08543, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-17K16571
[Journal Article] Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer development and progression2018
- Author(s)
  Eto T, Miyake K, Nosho K, Ohmuraya M, Imamura Y, Arima K, Kanno S, Fu L, Kiyozumi Y, Izumi D, Sugihara H, Hiyoshi Y, Miyamoto Y, Sawayama H, Iwatsuki M, Baba Y, Yoshida N, Furukawa T, Araki K, Baba H, Ishimoto T
- Journal Title
  
  The Journal of Pathology
  
  Volume: 245 Issue: 4 Pages: 445-455
- DOI
  10.1002/path.5098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10639, KAKENHI-PROJECT-18K15788, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K07145, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-17K16571
[Journal Article] PD-L1 Expression, Tumor-infiltrating Lymphocytes, and Clinical Outcome in Patients With Surgically Resected Esophageal Cancer.2017
- Author(s)
  Yagi T, Baba Y, Ishimoto T, Iwatsuki M, Miyamoto Y, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  Ann Surg.
  
  Volume: Dec 4 Issue: 3 Pages: 471-478
- DOI
  10.1097/sla.0000000000002616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17H04273, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-19K18094
[Journal Article] Colorectal Cancer Stem Cells Acquire Chemoresistance Through the Upregulation of F-Box/WD Repeat-Containing Protein 7 and the Consequent Degradation of c-Myc.2017
- Author(s)
  Izumi D, Ishimoto T, Miyake K, Eto T, Arima K, Kiyozumi Y, Uchihara T, Kurashige J, Iwatsuki M, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Goel A, Tan P, Baba H.
- Journal Title
  
  Stem Cells.
  
  Volume: 35(9) Issue: 9 Pages: 2027-2036
- DOI
  10.1002/stem.2668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17K16570, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-15K10122, KAKENHI-PROJECT-16K15595
[Journal Article] The microbiome and hepatobiliary-pancreatic cancers.2017
- Author(s)
  Mima K, Nakagawa S, Sawayama H, Ishimoto T, Imai K, Iwatsuki M, Hashimoto D, Baba Y, Yamashita YI, Yoshida N, Chikamoto A, Baba H
- Journal Title
  
  Cancer Lett.
  
  Volume: 402 Pages: 9-15
- DOI
  10.1016/j.canlet.2017.05.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K19942
[Journal Article] Fusobacterium nucleatum in gastroenterological cancer: Evaluation of measurement methods using quantitative polymerase chain reaction and a literature review.2017
- Author(s)
  Yamamura K, Baba Y, Miyake K, Nakamura K, Shigaki H, Mima K, Kurashige J, Ishimoto T, Iwatsuki M, Sakamoto Y, Yamashita Y, Yoshida N, Watanabe M, Baba H
- Journal Title
  
  Oncol Lett
  
  Volume: 14(6) Pages: 6373-6378
- DOI
  10.3892/ol.2017.7001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-17K10596
[Journal Article] Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells.2017
- Author(s)
  Ishimoto T, Miyake K, Nandi T, Yashiro M, Onishi N, Huang KK, Joyce LN, Kalpana R, Tay ST, Suzuki Y, Cho BC, Kuroda D, Arima K, Izumi D, Iwatsuki M, Baba Y, Oki E, Watanabe M, Saya H, Hirakawa K, Baba H, Tan P.
- Journal Title
  
  Gastroenterology
  
  Volume: in press Issue: 1 Pages: 191-204
- DOI
  10.1053/j.gastro.2017.03.046
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-26293290, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-16K07125, KAKENHI-PROJECT-17K10596, KAKENHI-PROJECT-17K10639, KAKENHI-PROJECT-26293307, KAKENHI-PROJECT-17H01401
[Journal Article] Clinical usefulness of postoperative C-reactive protein/albumin ratio in pancreatic ductal adenocarcinoma.2017
- Author(s)
  Arima K, Yamashita YI, Hashimoto D, Nakagawa S, Umezaki N, Yamao T, Tsukamoto M, Kitano Y, Yamamura K, Miyata T, Okabe H, Ishimoto T, Imai K, Chikamoto A, Baba H.
- Journal Title
  
  Am J Surg.
  
  Volume: Aug 26 Issue: 1 Pages: 111-115
- DOI
  10.1016/j.amjsurg.2017.08.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-18K16370, KAKENHI-PROJECT-17K16570
[Journal Article] C5a receptor (CD88) promotes motility and invasiveness of gastric cancer by activating RhoA.2016
- Author(s)
  Kaida T, Nitta H, Kitano Y, Yamamura K, Arima K, Izumi D, Higashi T, Kurashige J, Imai K, Hayashi H, Iwatsuki M, Ishimoto T, Hashimoto D, Yamashita Y, Chikamoto A, Imanura T, Ishiko T, Beppu T, Baba H.
- Journal Title
  
  Oncotarget.
  
  Volume: 20(7) Issue: 51 Pages: 84798-84809
- DOI
  10.18632/oncotarget.12656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19900, KAKENHI-PROJECT-15K10171, KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-16K10503
[Journal Article] Human Microbiome Fusobacterium Nucleatum in Esophageal Cancer Tissue Is Associated with Prognosis2016
- Author(s)
  Yamamura K, Baba Y, Nakagawa S, Mima K, Miyake K, Nakamura K, Sawayama H, Kinoshita K, Ishimoto T, Iwatsuki M, Sakamoto Y, Yamashita Y, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 22(22) Issue: 22 Pages: 5574-5581
- DOI
  10.1158/1078-0432.ccr-16-1786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10504, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-16K19942
[Journal Article] Fibroblast growth factor receptor 2 expression, but not its genetic amplification, is associated with tumor growth and worse survival in esophagogastric junction adenocarcinoma.2016
- Author(s)
  Tokunaga R, Imamura Y, Nakamura K, Ishimoto T, Nakagawa S, Miyake K, Nakaji Y, Tsuda Y, Iwatsuki M, Baba Y, Sakamoto Y, Miyamoto Y, Saeki H, Yoshida N, Oki E, Watanabe M, Oda Y, Bass AJ, Maehara Y, Baba H.
- Journal Title
  
  Oncotarget
  
  Volume: in press Issue: 15 Pages: 19748-61
- DOI
  10.18632/oncotarget.7782
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25861203, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-26293290, KAKENHI-PROJECT-16K15595, KAKENHI-PROJECT-16K19943
[Journal Article] The role of microRNA in esophageal squamous cell carcinoma.2016
- Author(s)
  Harada K, Baba Y, Ishimoto T, Shigaki H, Kosumi K, Yoshida N, Watanabe M, Baba H.
- Journal Title
  
  J Gastroenterol
  
  Volume: 51(6) Issue: 6 Pages: 520-30
- DOI
  10.1007/s00535-016-1161-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293290
[Journal Article] CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin β1 clustering and invasiveness in gastric cancer.2016
- Author(s)
  Izumi D, Ishimoto T, Miyake K, Sugihara H, Eto K, Sawayama H, Yasuda T, Kiyozumi Y, Kaida T, Kurashige J, Imamura Y, Hiyoshi Y, Iwatsuki M, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Takamori H, Araki N, Tan P, Baba H.
- Journal Title
  
  Int J Cancer
  
  Volume: 1;138(5) Issue: 5 Pages: 1207-19
- DOI
  10.1002/ijc.29864
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462047, KAKENHI-PROJECT-15K14383, KAKENHI-PROJECT-14F04099, KAKENHI-PROJECT-25293312, KAKENHI-PROJECT-16H06257, KAKENHI-PROJECT-16K19942, KAKENHI-PROJECT-16H05440
[Journal Article] The sensitivity of gastric cancer to trastuzumab is regulated by the miR-223/FBXW7 pathway2015
- Author(s)
  Eto K, Iwatsuki M, Watanabe M, Ishimoto T, Ida S, Imamura Y, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Baba H
- Journal Title
  
  Int J Cancer
  
  Volume: 136(7) Issue: 7 Pages: 1537-45
- DOI
  10.1002/ijc.29168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591948, KAKENHI-PROJECT-24591949, KAKENHI-PROJECT-25462027, KAKENHI-PROJECT-26293290, KAKENHI-PROJECT-26461982, KAKENHI-PROJECT-24591950
[Journal Article] miR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells.2015
- Author(s)
  Higashi, T., Hayashi, H., Ishimoto, T., Takeyama, H., Kaida, T., Arima, K., Taki, K., Sakamoto, K., Kuroki, H., Okabe, H., Nitta, H., Hashimoto, D., Chikamoto, A., Beppu, T., Baba, H.
- Journal Title
  
  Br J Cancer
  
  Volume: 14;113(2) Issue: 2 Pages: 252-8
- DOI
  10.1038/bjc.2015.170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462098, KAKENHI-PROJECT-26861089, KAKENHI-PROJECT-26293290
[Journal Article] Suppressor microRNA-145 is epigenetically regulated by promoter hypermethylation in esophageal squamous cell carcinoma.2015
- Author(s)
  Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwagami S, Miyamoto Y, Sakamoto Y, Yoshida N, Oki E, Watanabe M, Baba H
- Journal Title
  
  Anticancer Res
  
  Volume: 35(9) Pages: 4617-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293290
[Journal Article] Chronic inflammation with helicobactor pylori-infectionis implicated in CD44 overexpression through miR-328 suppression in the gastric mucosa.2015
- Author(s)
  Ishimoto T, Izumi D, Watanabe M, Yoshida N, Hidaka K, Miyake K, Sugihara H, Sawayama H, ImamuraY, Iwatsuki M, Iwagami S, Baba Y, Horlad H, Komohara Y, Takeya M, Baba H
- Journal Title
  
  J Gastroenterol
  
  Volume: 50 Issue: 7 Pages: 751-757
- DOI
  10.1007/s00535-014-1019-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950
[Journal Article] Analysis of circulating tumor cells derived from advanced gastric cancer.2015
- Author(s)
  Toyoshima K, Hayashi A, Kashiwagi M, Hayashi N, Iwatsuki M, Ishimoto T, Baba Y, Baba H, Ohta Y
- Journal Title
  
  Int J Cancer
  
  Volume: 137(4) Issue: 4 Pages: 991-8
- DOI
  10.1002/ijc.29455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293290
[Journal Article] An Imbalance in TAZ and YAP Expression in Hepatocellular Carcinoma Confers Cancer Stem Cell-like Behaviors Contributing to Disease Progression.2015
- Author(s)
  Hayashi H, Higashi T, Yokoyama N, Kaida T, Sakamoto K, Fukushima Y, Ishimoto T, Kuroki H, Nitta H, Hashimoto D, Chikamoto A, Oki E, Beppu T, Baba H.
- Journal Title
  
  Cancer Res.
  
  Volume: 75(22) Issue: 22 Pages: 4985-97
- DOI
  10.1158/0008-5472.can-15-0291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10191, KAKENHI-PROJECT-26462046, KAKENHI-PROJECT-25462098, KAKENHI-PROJECT-26293290
[Journal Article] Suppressor microRNA-145 is epigenetically regulated by promoter hypermethylation in esophageal squamous cell carcinoma2015
- Author(s)
  Harada K, Baba Y, Ishimoto T, Kosumi K, Tokunaga R, Izumi D, Ohuchi M, Nakamura K, Kiyozumi Y, Kurashige J, Iwagami S. Miyamoto Y, Sakamoto Y, Yoahida N, Watanabe M, Baba H
- Journal Title
  
  Anticancer Res
  
  Volume: 35 Pages: 4617-4624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950
[Journal Article] Noncoding RNA expression aberration is associated with cancer progression and is a potential biomarker in esophageal squamous cell carcinoma2015
- Author(s)
  Sugihara H., Ishimoto T., Miyake K., Izumi D., Baba Y., Yoshida N., Watanabe M., Baba H
- Journal Title
  
  Int J Mol Sci
  
  Volume: 16 Issue: 11 Pages: 27824-27834
- DOI
  10.3390/ijms161126060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-26293290
[Journal Article] バイオマーカーをめぐるQ&A(Question5)　胃癌におけるmicroRNA21/PTEN経路を介したトラスツズマブ耐性(Q&A)2014
- Author(s)
  江藤　弘二郎、岩槻　政晃、石本　崇胤、馬場　秀夫
- Journal Title
  
  Surgery Frontier
  
  Volume: 21(2) Pages: 220-23
- Data Source
  KAKENHI-PROJECT-25462027
[Journal Article] The microRNA-21/PTEN pathway regulates the sensitivity of HER2-positive gastric cancer cells to trastuzumab2014
- Author(s)
  Eto K, Iwatsuki M, Watanabe M, Ida S, Ishimoto T, Iwagami S, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21(1) Issue: 1 Pages: 343-50
- DOI
  10.1245/s10434-013-3325-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591949, KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-25462027, KAKENHI-PROJECT-26461982
[Journal Article] IGF2 DMR0 methylation, loss of imprinting, and patient prognosis inesophageal squamous cell carcinoma2014
- Author(s)
  A. Murata, Y. Baba, M. Watanabe, H. Shigaki, K. Miyake, T. Ishimoto, M. Iwatsuki, S. Iwagami, N. Yoshida, E. Oki, M. Morita, M. Nakao, and H. Baba.
- Journal Title
  
  Ann. Surg. Oncol.
  
  Volume: 21 Issue: 4 Pages: 1166-1174
- DOI
  10.1245/s10434-013-3414-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23116009, KAKENHI-PROJECT-24591966, KAKENHI-PROJECT-24659152, KAKENHI-PROJECT-24659617, KAKENHI-PROJECT-26461953
[Journal Article] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation.2014
- Author(s)
  Ishimoto T
- Journal Title
  
  Carcinogenesis
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462027
[Journal Article] Changes in Body Composition Secondary to Neoadjuvant Chemotherapy for Advanced Esophageal Cancer are Related to the Occurrence of Postoperative Complications After Esophagectomy.2014
- Author(s)
  Ida S, Watanabe M, Karashima R, Imamura Y, Ishimoto T, Baba Y, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21 Issue: 11 Pages: 3675-3679
- DOI
  10.1245/s10434-014-3737-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950
[Journal Article] LINE-1 hypomethylation, DNA copy number alterations, and CDK6 amplification in esophageal squamous cell carcinoma2014
- Author(s)
  Y. Baba, M. Watanabe, A. Murata, H. Shigaki, K. Miyake, T. Ishimoto, M. Iwatsuki, S. Iwagami, N. Yoshida, E. Oki, K. Sakamaki, M. Nakao, and H. Baba.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 20 Issue: 5 Pages: 1114-1124
- DOI
  10.1158/1078-0432.ccr-13-1645
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116009, KAKENHI-PROJECT-23689061, KAKENHI-PROJECT-24659152, KAKENHI-PROJECT-24659617, KAKENHI-PROJECT-25462027
[Journal Article] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation2014
- Author(s)
  Ishimoto T, Sugihara H, Watanabe M, Sawayama H, Iwatsuki M, Baba Y, Okabe H, Hidaka K, Yokoyama N, Miyake K, Yoshikawa M, Nagano O, Komohara Y, Takeya M, Saya H, Baba H.
- Journal Title
  
  Carcinogenesis
  
  Volume: 35(5) Issue: 5 Pages: 1003-11
- DOI
  10.1093/carcin/bgt402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-26293290
[Journal Article] Outcomes of preoperative chemotherapy with docetaxel, cisplatin, and 5-fluorouracil followed by esophagectomy in patients with resectable node-positive esophageal cancer.2014
- Author(s)
  140 Watanabe M., Baba Y., Yoshida N., Ishimoto T., Nagai Y., Iwatsuki M., Iwagami S., Baba H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: Epub ahead of print Issue: 9 Pages: 2838-2844
- DOI
  10.1245/s10434-014-3684-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950
[Journal Article] Influence of preoperative docetaxel, cisplatin, and 5-fluorouracil on the incidence of complication after esophagectomy for resectable advanced esophageal cancer2014
- Author(s)
  108 Yoshida N., Watanabe M., Baba Y., Ishimoto T., Iwagami S., Sakamoto Y., Miyamoto Y., Karashima R., Baba H
- Journal Title
  
  Dis Esophagus
  
  Volume: 27 Issue: 4 Pages: 374-379
- DOI
  10.1111/dote.12117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-25462028
[Journal Article] LINE-1 hypomethylation in gastric cancer, detected by bisulfite pyrosequencing, is associated with poor prognosis.2013
- Author(s)
  Shigaki H, Baba Y, et al.
- Journal Title
  
  Gastric Cancer
  
  Volume: in　press Issue: 4 Pages: 480-487
- DOI
  10.1007/s10120-012-0209-7
- NAID
  40019845213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689061, KAKENHI-PROJECT-24591948, KAKENHI-PROJECT-24659617
[Journal Article] Methylation levels of LINE-1 in primary lesion and matched metastatic lesions of colorectal cancer.2013
- Author(s)
  Murata A, Baba Y, Watanabe M, Shigaki H, Miyake K, Ishimoto T, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Nosho K, Baba H.
- Journal Title
  
  Br J Cancer.
  
  Volume: 109 Issue: 2 Pages: 408-415
- DOI
  10.1038/bjc.2013.289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591941, KAKENHI-PROJECT-24659617, KAKENHI-PROJECT-25670588
[Journal Article] LINE-1 hypomethylation is associated with a poor prognosis among patients with curatively resected esophageal squamous cell carcinoma2013
- Author(s)
  Iwagami S, Baba Y, Watanabe M, Shigaki H, Miyake K, Ishimoto T, Iwatsuki M, Sakamaki K, Ohashi Y, Baba H
- Journal Title
  
  Ann Surg
  
  Volume: 257(3) Issue: 3 Pages: 449-55
- DOI
  10.1097/sla.0b013e31826d8602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689061, KAKENHI-PROJECT-24659617
[Journal Article] Functional role of CD44v-xCT system in the development of spasmolytic polypeptide-expressing metaplasia2013
- Author(s)
  Wada T, Ishimoto T, Seishima R, Tsuchihashi K, Yoshikawa M, et al
- Journal Title
  
  Cancer Science
  
  Volume: 104 Issue: 10 Pages: 1323-9
- DOI
  10.1111/cas.12236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J06428, KAKENHI-PLANNED-22130007, KAKENHI-PROJECT-24590389, KAKENHI-PROJECT-24591912
[Journal Article] Identification of miR-30e*regulation of Bmi1 expression mediated by tumor-assocated macrophages in gastrointestinal cancer.2013
- Author(s)
  117 Sugihara H, Ishimoto T., Watanabe M., Sawayama H., Iwatsuki M., Baba Y., Kamohara Y., Takeya M., Baba H
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e81839-e81839
- DOI
  10.1371/journal.pone.0081839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591950, KAKENHI-PROJECT-25293089, KAKENHI-PROJECT-26293290
[Journal Article] Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Ishimoto T, Miyake K,Yokoyama N, Ishiko T, Baba2012
- Author(s)
  Kinoshita H, Okabe H, Beppu T,Chikamoto A, Hayashi H, Imai K, MimaK, Nakagawa S, Ishimoto T, Miyake K,Yokoyama N, Ishiko T, Baba
- Journal Title
  
  Oncol Rep
  
  Volume: 29 Issue: 2 Pages: 685-9
- DOI
  10.3892/or.2012.2162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791292, KAKENHI-PROJECT-23791549, KAKENHI-PROJECT-24591912, KAKENHI-PROJECT-24592008
[Journal Article] LINE-1 hypomethylation in noncancerous esophageal mucosae is associated with smoking history2012
- Author(s)
  Shigaki H, Baba Y, Watanabe M, Iwagami S, Miyake K, Ishimoto T, Iwatsuki M, Baba H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19(13) Issue: 13 Pages: 4238-43
- DOI
  10.1245/s10434-012-2488-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23689061, KAKENHI-PROJECT-24659617
[Presentation] スキルス胃がん間質リプログラミングは抗PD-1抗体治療の効果を高める2024
- Author(s)
  石本　崇胤
- Organizer
  第96回日本胃癌学会　ワークショップ 13　スキルス胃癌に対する治療戦略
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] シングルセル解析による腫瘍微小環境ダイバーシティの検討2024
- Author(s)
  石本　崇胤
- Organizer
  藤田医科大学第19回がん医療研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] PDGFRを標的とした間質リプログラミングは抗PD-1抗体治療の効果を高める2024
- Author(s)
  石本　崇胤
- Organizer
  第33回日本がん転移学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] シングルセル解析による腫瘍微小環境ダイバーシティの検討2024
- Author(s)
  石本　崇胤
- Organizer
  群馬大学外科診療センターグランドカンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] がんと間質・線維化に関するトピックス～現状と課題～2024
- Author(s)
  石本　崇胤
- Organizer
  大鵬薬品工業社内研修会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] シングルセル解析による腫瘍微小環境ダイバーシティの検討2024
- Author(s)
  石本　崇胤
- Organizer
  第33回日本癌病態治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Single-cell proteomic profiling of malignant ascites in gastric cancer reveals the microenvironment promoting peritoneal dissemination2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  JSPS Core-to-Core Program A. Mini-Symposium 「Applications of mass cytometry in basic and clinical research」
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19535
[Presentation] tromal reprogramming boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors.2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  9th Annual Meeting of Korean Cancer Association Symposium04 Understanding tumor ecosystems
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27463
[Presentation] 腫瘍間質多様性を評価する空間的遺伝子解析のコツとピットフォール2023
- Author(s)
  石本　崇胤
- Organizer
  10XGenomics オンラインシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Single-cell proteomic profiling of malignant ascites in gastric cancer reveals the microenvironment promoting peritoneal dissemination2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  JSPS Core-to-Core Program AMini-Symposium 「Applications of mass cytometry in basic and clinical research」
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] シングルセル解析による腫瘍間質多様性の検討2023
- Author(s)
  石本　崇胤
- Organizer
  第19回日本病理学会カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Stromal reprogramming boosts the efficacy of anti-PD-1 immunotherapy in fibrotic tumors.2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  49th Annual Meeting of Korean Cancer Association Symposium04 Understanding tumor ecosystems.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] 腫瘍微?環境を標的とした治療戦略の確?に向けて2023
- Author(s)
  石本　崇胤
- Organizer
  国立がんセンター東病院　TR・国際研究推進セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] 新規高度多重免疫染色技術を用いた胃癌における癌関連線維芽細胞の空間的一細胞解析2023
- Author(s)
  千場隆、王懐涛、米村敦子、トン依霖、石本崇胤
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27689
[Presentation] シングルセルRNA-seq解析による胃癌間質細胞の多様性に関する検討2023
- Author(s)
  千場隆、米村敦子、山崎昌哉、石本崇胤
- Organizer
  NGS EXPO 2023
- Data Source
  KAKENHI-PROJECT-23K27689
[Presentation] シングルセル解析による腫瘍間質多様性の検討2023
- Author(s)
  石本　崇胤
- Organizer
  第19回日本病理学会カンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-23K27463
[Presentation] esothelial-mesenchymal transition induced mesothelial cells enhance peritoneal dissemination through forming protumorigenic microenviroment.2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  2023 Inflammaging Translational Research Center International Symposium. Session ⅡInflammaging.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27463
[Presentation] Mesothelial-mesenchymal transition induced mesothelial cells enhance peritoneal dissemination through forming protumorigenic microenviroment.2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  2023 Inflammaging Translational Research Center International Symposium. Session ⅡInflammaging.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] 腫瘍間質多様性を評価する空間的遺伝子解析のコツとピットフォール2023
- Author(s)
  石本　崇胤
- Organizer
  10XGenomics オンラインシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K27463
[Presentation] 腫瘍微小環境を標的とした治療戦略の確立に向けて2023
- Author(s)
  石本　崇胤
- Organizer
  国立がんセンター東病院　TR・国際研究推進セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K27463
[Presentation] Single-cell proteomic profiling of malignant ascites in gastric cancer reveals the microenvironment promoting peritoneal dissemination2023
- Author(s)
  Takatsugu Ishimoto
- Organizer
  JSPS Core-to-Core Program A. Mini-Symposium 「Applications of mass cytometry in basic and clinical research」
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Single-cell proteomic profiling of malignant ascites in gastric cancer reveals the microenvironment promoting peritoneal dissemination2022
- Author(s)
  Takatsugu Ishimoto
- Organizer
  第45回日本分子生物学会年会、フォーラム2F-07 「個体レベルの生命科学の創発」
- Invited
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Single-cell proteomic profiling of malignant ascites in gastric cancer reveals the microenvironment promoting peritoneal dissemination2022
- Author(s)
  Takatsugu Ishimoto
- Organizer
  第45回日本分子生物学会年会、フォーラム2F-07 「個体レベルの生命科学の創発」
- Invited
- Data Source
  KAKENHI-PROJECT-21K19535
[Presentation] PDGFR阻害によるスキルス胃癌間質リプログラミングを介した複合がん免疫療法2022
- Author(s)
  石本　崇胤
- Organizer
  第33回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] Single-cell proteomic profiling of malignant ascites in gastric cancer reveals the microenvironment promoting peritoneal dissemination2022
- Author(s)
  Takatsugu Ishimoto
- Organizer
  第45回日本分子生物学会年会、フォーラム2F-07 「個体レベルの生命科学の創発」
- Invited
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] 膵癌が産生する乳酸が腫瘍微小環境に与える分子生物学的検討2022
- Author(s)
  北村　文優、石本　崇胤
- Organizer
  日本外科学会
- Data Source
  KAKENHI-PROJECT-20K09038
[Presentation] PDGFR阻害によるスキルス胃癌間質リプログラミングを介した複合がん免疫療法2022
- Author(s)
  石本　崇胤
- Organizer
  第33回日本消化器癌発生学会総会　シンポジウム１「免疫を考慮した消化器癌研究」
- Data Source
  KAKENHI-PROJECT-21K19535
[Presentation] スキルス胃癌免疫微小環境リモデリングによる治療戦略2022
- Author(s)
  石本崇胤
- Organizer
  第93回日本胃癌学会総会、ワークショップ６「胃癌における微小環境の分子機序の解明と臨床的意義
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] スキルス胃癌免疫微小環境リモデリングによる治療戦略2022
- Author(s)
  石本崇胤
- Organizer
  第93回日本胃癌学会総会、ワークショップ６「胃癌における微小環境の分子機序の解明と臨床的意義
- Data Source
  KAKENHI-PROJECT-21K19535
[Presentation] PDGFR阻害によるスキルス胃癌間質リプログラミングを介した複合がん免疫療法2022
- Author(s)
  石本　崇胤
- Organizer
  第33回日本消化器癌発生学会総会　シンポジウム１「免疫を考慮した消化器癌研究」
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] スキルス胃癌免疫微小環境リモデリングによる治療戦略2022
- Author(s)
  石本　崇胤
- Organizer
  第93回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] Senescent-CAFs in malignant ascites enhance peritoneal tumor formation2022
- Author(s)
  Tadahito Yasuda, Mayu Koiwa, Hideo Baba, Takatsugu Ishimoto
- Organizer
  IGCC2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 複合がん免疫療法に向けたスキルス胃癌間質リプログラミング分子基盤の解明2021
- Author(s)
  石本崇胤
- Organizer
  第29回JDDW 2021シンポジウム8「がん微小環境を標的とした消化器がん治療の新展望」
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Elucidation of immune microenvironment and therapeutic target in scirrhous gastric cancer strorma.2021
- Author(s)
  Takatsugu Ishimoto
- Organizer
  第93回日本胃癌学会総会　会長特別企画2スキルス胃癌研究のこれまでとこれから
- Invited
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] がん性腹水中senescent-CAFsによる腹膜播種促進メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第29回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 複合がん免疫療法に向けたスキルス胃癌間質リプログラミング分子基盤の解明2021
- Author(s)
  石本崇胤
- Organizer
  第29回JDDW 2021シンポジウム8「がん微小環境を標的とした消化器がん治療の新展望」
- Data Source
  KAKENHI-PROJECT-21K19535
[Presentation] Extracellular vesicles from cancer-associated fibroblasts induce drug resistance.2021
- Author(s)
  Takatsugu Ishimoto
- Organizer
  34th Workshop of the European Helicobacter and Microbiota Study Group
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21KK0153
[Presentation] Extracellular vesicles from cancer-associated fibroblasts induce drug resistance.2021
- Author(s)
  Takatsugu Ishimoto
- Organizer
  34th Workshop of the European Helicobacter and Microbiota Study Group
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19535
[Presentation] 癌性腹水中Senescent-CAFsによる腹膜播種促進メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第93回日本胃癌学会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 腫瘍間質細胞によって促進される胃癌腹膜播種進展メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第32回日本消化器癌発生学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 複合がん免疫療法に向けたスキルス胃癌間質リプログラミング分子基盤の解明2021
- Author(s)
  石本　崇胤
- Organizer
  第29回JDDW 2021シンポジウム8「がん微小環境を標的とした消化器がん治療の新展望」
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] 全身性炎症を背景とする病態を制御し、難治癌の克服を目指すトランスレーショナル研究2021
- Author(s)
  安田忠仁、小岩麻由、米村敦子、ブルコ、馬場秀夫、石本崇胤
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 癌性腹水中SASP-CAFsによる腹膜播種促進メカニズムの解明2021
- Author(s)
  安田忠仁、小岩麻由、馬場秀夫、石本崇胤
- Organizer
  第29回JDDW
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] 34th Workshop of the European Helicobacter and Microbiota Study Group2021
- Author(s)
  Takatsugu Ishimoto
- Organizer
  Extracellular vesicles from cancer-associated fibroblasts induce drug resistance.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] 食道扁平上皮癌におけるGLUT1発現と腫瘍増殖およびCDDP感受性の関係に関する検討2020
- Author(s)
  澤山浩, 石本崇胤, 吉田直矢, 日吉幸晴, 岩槻政晃, 宮本裕士, 平尾洸樹, 坂田和也, 高田登, 吉仲一郎, 原田和則, 馬場秀夫
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K09199
[Presentation] 腹膜播種形成を促進するがん性腹水中老化細胞の意義2020
- Author(s)
  石本　崇胤
- Organizer
  第20回抗加齢医学会総会シンポジウム3「DNA損傷応答と老化の表現型」
- Invited
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] 胃がん間質ダイバーシティの解明と治療標的の創出2020
- Author(s)
  石本　崇胤
- Organizer
  第31回日本消化器癌発生学会総会　田原榮一賞受賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-20H03531
[Presentation] 胃癌由来CAFsの老化と腹膜播種進展機序の解明2020
- Author(s)
  安田忠仁、石本崇胤、小岩麻由、米村敦子、三宅慧輔、内原智幸、江藤弘二郎、岩上志朗、馬場祥史、岩槻政晃、吉田直矢、馬場秀夫
- Organizer
  第120回日本外科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] Gastric cancer CAFs maintain SASP through epigenetic histone modification and enhance peritoneal dissemination2020
- Author(s)
  Tadahito Yasuda, Mayu Koiwa, Atsuko Yonemura, Keisuke Miyake, Luke Bu, Hideo Baba, and Takatsugu Ishimoto
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08985
[Presentation] Glucose Transporter 1 regulate cell glycolysis and proliferation in Gastrointestinal stromal tumor and its clinicopathological significance.2020
- Author(s)
  Masaaki Iwatsuki, Hiroshi Sawayama, Daisuke Kuroda, Yuki Koga, Kazuto Harada, Kohei Yamashita, Shiro Iwagami, Kojiro Eto, Takatsugu Ishimoto, Yoshifumi Baba, Naoya Yoshida, Jaffer A. Ajani and Hideo Baba
- Organizer
  2019 AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09199
[Presentation] Fusobacterium nucleatumの食道癌進展への関与とそのメカニズム；腫瘍免疫、NF-kB経路との関連2019
- Author(s)
  野元大地、馬場祥史、秋山貴彦、岡留一雄、山下晃平、坂本悠樹、大徳暢哉、織田枝里、内原智幸、徳永竜馬、原田和人、山村謙介、江藤弘二郎、日吉幸晴、長井洋平、岩槻政晃、石本崇胤、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18K19586
[Presentation] 大腸癌患者におけるカヘキシア関連分子Activin A発現の臨床的意義2019
- Author(s)
  1.大徳　暢哉、宮本　裕士、坂本　悠樹、江藤　弘二郎、日吉　幸晴、長井　洋平、石本　崇胤、馬場　祥史、岩上　志朗、吉田　直矢、馬場　秀夫
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] 大腸癌肝転移巣における細菌Fusobacterium nucleatumとCD8陽性T細胞数との関連2019
- Author(s)
  美馬浩介、坂本悠樹、江藤弘二郎、日吉幸晴、今井克憲、岩槻政晃、石本崇胤、岩上志朗、馬場祥史、宮本裕士、山下洋市、吉田直矢、馬場秀夫
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18H02694
[Presentation] 大腸癌肝転移巣における細菌Fusobacterium nucleatumとCD8陽性T細胞数との関連2019
- Author(s)
  美馬浩介、坂本悠樹、江藤弘二郎、日吉幸晴、今井克憲、岩槻政晃、石本崇胤、岩上志朗、馬場祥史、宮本裕士、山下洋市、吉田直矢、馬場秀夫
- Organizer
  第40回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-18K19586
[Presentation] 腫瘍微小環境に依存する胃がん浸潤性増殖機構の解明2019
- Author(s)
  石本崇胤、三宅慧輔、米村敦子、安田忠仁、伊東山瑠美、内原智幸、吉田直矢、馬場秀夫
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08543
[Presentation] 上部消化管腺癌における腫瘍内Fusobacterium nucleatumと予後2019
- Author(s)
  原田和人、織田枝里、馬場祥史、長井洋平、宮本裕士、石本崇胤、岩槻政晃、吉田直矢、Jaffer A. Ajani、馬場秀夫
- Organizer
  第73回日本食道学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02694
[Presentation] 大腸癌におけるPNIおよび腫瘍内CD8陽性T細胞と予後の関連2019
- Author(s)
  2.大徳　暢哉、宮本　裕士、坂本　悠樹、日吉　幸晴、石本　崇胤、岩槻　政晃、馬場　祥史、岩上　志朗、吉田　直矢、馬場　秀夫
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] Fusobacterium nucleatumの食道癌進展への関与とそのメカニズム；腫瘍免疫、NF-kB経路との関連2019
- Author(s)
  野元大地、馬場祥史、秋山貴彦、岡留一雄、山下晃平、坂本悠樹、大徳暢哉、織田枝里、内原智幸、徳永竜馬、原田和人、山村謙介、江藤弘二郎、日吉幸晴、長井洋平、岩槻政晃、石本崇胤、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H02694
[Presentation] 上部消化管腺癌における腫瘍内Fusobacterium nucleatumと予後2019
- Author(s)
  原田和人、織田枝里、馬場祥史、長井洋平、宮本裕士、石本崇胤、岩槻政晃、吉田直矢、Jaffer A. Ajani、馬場秀夫
- Organizer
  第73回日本食道学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19586
[Presentation] Extracellular vesicles from cancer associated fibroblasts induce drug resistance via integrinβ1/FAK signaling in gastric cancer cells2019
- Author(s)
  1.Takatsugu Ishimoto、Tomoyuki Uchihara, Keisuke Miyake, Atsuko Yonemura, Tadahito Yasuda, Rumi Itoyama, Masaaki Iwatsuki, Yoshifumi Baba, Naoya Yoshida, Hideo Baba
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 腫瘍におけるアクチビンAの発現は大腸癌患者の予後と関連している2018
- Author(s)
  Nobuya Daitoku、Yuji Miyamoto, Yuki Sakamoto, Kojiro Eto, Yukiharu Hiyoshi, Masaaki Iwatsuki, Takatsugu Ishimoto, Yoshifumi Baba, Shiro Iwagami, Naoya Yoshida, Hideo Baba
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] Inhibition of 15-PGDH causes Kras-driven tumor expansion through all-trans retinoic acid metabolism in the pancreas.2018
- Author(s)
  Ishimoto T, Arima K, Baba Y, Yamashita Y, Baba H.
- Organizer
  American Association for Cancer Research Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] Expansion of pancreatic cancer stem-like cells through PGE2 accumulation in inflammatory environment2018
- Author(s)
  3.Takatsugu Ishimoto, Kota Arima,Luke Bu,Tomoyuki Uchihara,Keisuke Miyake,Tsugio Eto,Rumi Itoyama,Hideo Baba
- Organizer
  AACR annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 食道癌におけるLINE-1メチル化と腫瘍免疫2018
- Author(s)
  馬場祥史、小澄敬祐、岡留一雄、八木泰佑、清住雄希、江藤弘二郎、日吉幸晴、長井洋平、石本崇胤、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19586
[Presentation] 腫瘍炎症環境において間質に依存する胃癌進展の分子メカニズム2018
- Author(s)
  4.石本崇胤、三宅慧輔、八代正和、内原智幸、有馬浩太、泉大輔、岩槻政晃、馬場祥史、渡邊雅之、Patrick Tan、馬場秀夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 腫瘍間質に依存するdiffuse-type胃がん浸潤性増殖機構の解明2018
- Author(s)
  2.石本崇胤、三宅慧輔、伊東山瑠美、内原智幸、吉田直矢、馬場秀夫
- Organizer
  第29回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] LINE-1 methylation level and local immune response in esophageal cancer2018
- Author(s)
  Yoshifumi Baba、Keisuke Kosumi, Daichi Nomoto, Kazuo Okadome, Taisuke Yagi, Yuki Kiyozumi, Kojiro Eto, Yukiharu Hiyoshi, Takatsugu Ishimoto, Masaaki Iwatsuki, Shiro Iwagami, Yuji Miyamoto, Naoya Yoshida, Hideo Baba
- Organizer
  The International Society for Disease of the Esophagus(ISDE)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02694
[Presentation] IDO1 high expression is associated with a poor prognosis in patients with esophageal cancer.2018
- Author(s)
  Yuki Kiyozumi, Yoshifumi Baba, Taisuke Yagi, Yuki Koga, Tomoyuki Uchihara, Daisuke Kuroda, Hiroshi Sawayama, Ryuichi Krashima, Yukiharu Hiyoshi, Takatsugu Ishimoto, Masaaki Iwatsuki, Yuji Miyamoto, Naoya Yoshida, Hideo Baba.
- Organizer
  Association for Cancer Research 2018
- Data Source
  KAKENHI-PROJECT-17K10596
[Presentation] アクチビンAは大腸癌患者の予後予測因子となりうる2018
- Author(s)
  大徳暢哉、宮本裕士、坂本悠樹、江藤弘二郎、日吉幸晴、長井洋平、石本崇胤、馬場祥史、岩上志朗、吉田直矢、馬場秀夫
- Organizer
  第29回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-17K10640
[Presentation] Activated-stroma by cancer-related inflammation enhances gastric cancer progression through activation of STAT1/3 signaling2018
- Author(s)
  三宅慧輔、内原智幸、江藤二男、有馬浩太、安田忠仁、付凌峰、米村敦子、岩槻政晃、馬場祥史、宮本裕士、吉田直矢、馬場秀夫、石本崇胤
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-18K08543
[Presentation] 個別化治療を目指したLINE-1メチル化レベル解析：予後予測、早期診断、免疫チェックポイント阻害剤のbiomarkerとしての可能性2018
- Author(s)
  馬場祥史、岡留一雄、八木泰佑、黒田大介、澤山浩、日吉幸晴、岩槻政晃、石本崇胤、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18H02694
[Presentation] 食道癌におけるLINE-1メチル化と腫瘍免疫2018
- Author(s)
  馬場祥史、小澄敬祐、岡留一雄、八木泰佑、清住雄希、江藤弘二郎、日吉幸晴、長井洋平、石本崇胤、岩上志朗、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02694
[Presentation] The relationship between Microbiome Fusobacterium Nucleatum and autophagy in esophageal cancer.2018
- Author(s)
  Liu Yang, Yoshifumi Baba, Shigeki Nakagawa, Hiroshi Sawayama, Takatsugu Ishimoto, Masaaki Iwatsuki, Yuji Miyamoto, Yoichi Yamashita, Naoya Yoshida, Hideo Baba.
- Organizer
  Association for Cancer Research 2018
- Data Source
  KAKENHI-PROJECT-17K10596
[Presentation] Impact of loss-of-function mutations at the RNF43 locus on colorectal cancer progression2018
- Author(s)
  Ishimoto T, Eto T, Miyake K, Fu L, Uchihara T, Arima K, Yasuda T, Itoyama R, Yoshida N, Baba H
- Organizer
  SGICC 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10639
[Presentation] RHBDF2 in stromal fibroblasts mediates TGF-β signaling and enhances gastric cancer cell invasion via intercellular crosstalk.2017
- Author(s)
  Ishimoto T, Miyake K, Yashiro M, Eto T, Izumi D, Arima K, Baba Y, Watanabe M, Hirakawa K, Baba H.
- Organizer
  American Association for Cancer Research Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 腫瘍間質ゲノム解析に基づいた胃癌浸潤を制御する新規分子機構の解明2017
- Author(s)
  石本崇胤、三宅慧輔、八代正和、江藤二男、有馬浩太、泉大輔、岩槻政晃、馬場祥史、渡邊雅之、平川弘聖、Patrick Tan、馬場秀夫
- Organizer
  第89回日本胃癌学会総会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] Prostaglandin E2 accumulation enhances the expansion of ALDH1-positive cells and Kras-driven tumorigenesis in the pancreas.2017
- Author(s)
  Arima K、Ishimoto T, Ohmuraya M, Miyake K, Eto T, Okabe H, Kitano Y, Yamamura K, Kaida T, Imai K, Hashimoto D, Chikamoto A, Baba H
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  ワシントン（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] RHBDF2 in stromal fibroblasts mediates TGF-β signaling and enhances gastric cancer cell invasion via intercellular crosstalk.2017
- Author(s)
  Ishimoto T, Miyake K, Yashiro M, Eto T, Izumi D, Arima K, Baba Y, Watanabe M, Hirakawa K, Baba H
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  ワシントン（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] Identification of a new molecule mediating gastric cancer invasion based on genomic analysis of cancer-associated fibroblasts.2017
- Author(s)
  Ishimoto T, Miyake K, Yashiro M, Eto T, Arima K, Izumi D, Baba Y, Hirakawa K, Tan P, Baba H.
- Organizer
  12th International gastric cancer congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 腫瘍間質に依存する diffuse type 胃癌浸潤の新しい分子機構の解明2017
- Author(s)
  石本崇胤、三宅慧輔、八代正和、江藤二男、有馬浩太、泉大輔、岩槻政晃、馬場祥史、吉田直矢、渡邊雅之、Patrick Tan、馬場秀夫
- Organizer
  第50回制癌剤適応研究会
- Place of Presentation
  ホテルクレメント徳島（徳島県）
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 大腸癌におけるRing Finger Protein 43 発現と腫瘍発育進展の検討2017
- Author(s)
  江藤二男、石本崇胤、内原智幸、八木泰佑、黒田大介、澤山浩、日吉幸晴、岩槻政晃、馬場祥史、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第 28 回消化器癌発生学会
- Data Source
  KAKENHI-PROJECT-17K10639
[Presentation] Prostaglandin E2 accumulation enhances the expansion of ALDH1-positive cells and Kras-driven tumorigenesis in the pancreas.2017
- Author(s)
  Arima K、Ishimoto T, Ohmuraya M, Miyake K, Eto T, Okabe H, Kitano Y, Yamamura K, Kaida T, Imai K, Hashimoto D, Chikamoto A, Baba H
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  ワシントン（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] 腫瘍炎症環境における間質とのクロストークを介したdiffuse-type胃癌進展機構2017
- Author(s)
  石本　崇胤、Patrick Tan、馬場秀夫
- Organizer
  JDDW 2017
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] RHBDF2 in stromal fibroblasts mediates TGF-β signaling and enhances gastric cancer cell invasion via intercellular crosstalk.2017
- Author(s)
  Ishimoto T, Miyake K, Yashiro M, Eto T, Izumi D, Arima K, Baba Y, Watanabe M, Hirakawa K, Baba H
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  ワシントン（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] Functional role of Ring Finger Protein 43 in intestinal stem cells during colorectal tumorigenesis2017
- Author(s)
  Eto T, Ishimoto T, Oda E, Kuroda D, Arima K, Ohuchi M, Nakamura K, Sawayama H, Kinoshita K, Iwatsuki M, Baba Y, Sakamoto Y, Yoshida N, Baba H.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10639
[Presentation] 腫瘍間質ゲノム解析に基づいた胃癌浸潤を制御する新規分子機構の解明2017
- Author(s)
  石本崇胤、三宅慧輔、八代正和、江藤二男、有馬浩太、泉大輔、岩槻政晃、馬場祥史、渡邊雅之、平川弘聖、Patrick Tan、馬場秀夫
- Organizer
  第89回日本胃癌学会総会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] 大腸癌進展における Ring Finger Protein 43（RNF43）の機能解析2017
- Author(s)
  江藤二男、石本崇胤、内原智之、織田絵里、問端輔、八木泰佑、黒田大介、有馬浩大、大内繭子、中村健一、澤山浩、木下浩一、岩槻政晃、馬場祥史、坂本快郎、吉田直矢、馬場秀夫
- Organizer
  第117 回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10639
[Presentation] Prostaglandin E2 accumulation enhances the expansion of ALDH1-positive tumor cells and Kras-driven tumorigenesis in pancreas.2017
- Author(s)
  Arima K, Ishimoto T, Ohmuraya M, Miyake K, Eto T, Okabe H, Kitano Y, Yamamura K, Kaida T, Imai K, Hashimoto D, Chikamoto A, Yamashita YI, Baba H.
- Organizer
  American Association for Cancer Research Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] Identification of molecular mechanism underlying diffuse-type gastric cancer invasion depending on tumor stroma.2017
- Author(s)
  Ishimoto T, Miyake K, Yashiro M, Eto T, Arima K, Izumi D, Baba Y, Hirakawa K, Tan P, Baba H.
- Organizer
  The 76th Annual Meeting of the Japan Cancer Association.
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 腫瘍間質に依存するびまん性胃癌浸潤分子メカニズムの同定2017
- Author(s)
  石本　崇胤、Patrick Tan、馬場秀夫
- Organizer
  第28回日本消化器癌発生学会
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] 慢性炎症関連シグナルの活性化に伴う膵癌進展メカニズムの解明2017
- Author(s)
  有馬浩太、石本崇胤、大村谷昌樹、三宅慧輔、内原智幸、塚本雅代、梅崎直紀、江藤二男、北野雄希、宮田辰徳、中川茂樹、岡部弘尚、今井克憲、馬場祥史、橋本大輔、近本亮、山下洋市、古川徹、荒木喜美、馬場秀夫
- Organizer
  第28回日本消化器癌発生学会
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] 15-PGDH inhibition enhances KRAS-driven tumor cell expansion via all-trans retinoic acid depletion in pancreas2017
- Author(s)
  Arima K, Ishimoto T, Ohmuraya M, Miyake K, Uchihara T, Eto T, Nakagawa S, Imai K, Hashimoto D, Chikamoto A, Yamashita YI, Baba H.
- Organizer
  The 76th Annual Meeting of the Japan Cancer Association.
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] 腫瘍間質ゲノム解析に基づいた胃癌浸潤を制御する新規分子機構の解明2017
- Author(s)
  石本崇胤、三宅慧輔、八代正和、江藤二男、有馬浩太、泉大輔、岩槻政晃、馬場祥史、渡邊雅之、平川弘聖、Patrick Tan、馬場秀夫
- Organizer
  第89回日本胃癌学会総会
- Place of Presentation
  広島国際会議場（広島県）
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] Cancer Associated Fibroblastsゲノム解析に基づいたdiffuse type胃癌浸潤を制御する新規遺伝子の同定2016
- Author(s)
  石本崇胤、三宅慧輔、八代正和、泉大輔、有馬浩太、馬場祥史、渡邊雅之、平川弘聖、Patrick Tan、馬場秀夫
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  アスティとくしま（徳島県）
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] Verification of mechanism that CSC markers are implicated in poor prognosis for pancreatic ductal adenocarcinoma.2016
- Author(s)
  Arima K, Ishimoto T, Ohmuraya M, Okabe H, Kitano Y, Yamamura K, Kaida T, Nakagawa S, Imai K, Hashimoto D, Chikamoto A, Yamashita Y, Baba H
- Organizer
  ESMO-ASIA 2016
- Place of Presentation
  シンガポール
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] Cancer Associated Fibroblasts (CAFs)ゲノム解析に基づいた胃癌浸潤を制御する新規遺伝子の同定2016
- Author(s)
  石本崇胤、三宅慧輔、八代正和、有馬浩太、泉大輔、澤山浩、岩槻政晃、馬場祥史、坂本快郎、吉田直矢、平川弘聖、馬場秀夫、Patrick Tan
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] Identification of the novel molecules mediating gastric cancer invasion based on genomic analysis of cancer-associated fibroblasts.2016
- Author(s)
  Ishimoto T, Miyake K, Nandi T, Yashiro M, Huang K, Arima K, Izumi D, Baba Y, Baba H, Tan P
- Organizer
  ESMO-ASIA 2016
- Place of Presentation
  シンガポール
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] Cancer Associated Fibroblasts (CAFs)ゲノム解析に基づいた胃癌浸潤を制御する新規遺伝子の同定2016
- Author(s)
  石本崇胤、三宅慧輔、八代正和、有馬浩太、泉大輔、澤山浩、岩槻政晃、馬場祥史、坂本快郎、吉田直矢、平川弘聖、馬場秀夫、Patrick Tan
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] がん幹細胞マーカーが膵癌進展を引き起こすメカニズムの解明2016
- Author(s)
  有馬浩太、石本崇胤、大村谷昌樹、三宅慧輔、江藤二男、甲斐田剛圭、東孝暁、岡部弘尚、新田英利、橋本大輔、近本　亮、山下洋市、馬場秀夫
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] 網羅的ゲノム解析に基づいた胃癌Cancer Associated Fibroblasts (CAFs) の特性解明2016
- Author(s)
  石本崇胤、三宅慧輔、八代正和、泉大輔、志垣博信、藏重淳二、岩槻政晃、馬場祥史、坂本快郎、宮本裕士、吉田直矢、平川弘聖、 Patrick Tan、馬場秀夫
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  リーガロイヤルホテル大阪（大阪府）
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] がん幹細胞マーカーが膵癌進展を引き起こすメカニズムの解明2016
- Author(s)
  有馬浩太、石本崇胤、大村谷昌樹、三宅慧輔、江藤二男、甲斐田剛圭、東孝暁、岡部弘尚、新田英利、橋本大輔、近本　亮、山下洋市、馬場秀夫
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] Identification of the novel molecules mediating gastric cancer invasion based on genomic analysis of cancer-associated fibroblasts.2016
- Author(s)
  Ishimoto T, Miyake K, Nandi T, Yashiro M, Huang K, Arima K, Izumi D, Baba Y, Baba H, Tan P
- Organizer
  ESMO-ASIA 2016
- Place of Presentation
  シンガポール
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] Identification of the novel molecules mediating gastric cancer invasion based on genomic analysis of cancer-associated fibroblasts.2016
- Author(s)
  Ishimoto T, Miyake K, Nandi T, Yashiro M, Huang K, Arima K, Izumi D, Baba Y, Baba H, Tan P
- Organizer
  ESMO-ASIA 2016
- Place of Presentation
  シンガポール
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] RHBDF2 in stromal fibroblasts mediates TGF-β signaling and enhances gastric cancer cell invasion via intercellular crosstalk.2016
- Author(s)
  Ishimoto T, Miyake K, Yashiro M, Eto T, Izumi D, Arima K, Baba Y, Watanabe M, Hirakawa K, Baba H
- Organizer
  AACR Annual Meeting 2017
- Place of Presentation
  ワシントン（米国）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06257
[Presentation] Cancer Associated Fibroblasts (CAFs)ゲノム解析に基づいた胃癌浸潤を制御する新規遺伝子の同定2016
- Author(s)
  石本崇胤、三宅慧輔、八代正和、有馬浩太、泉大輔、澤山浩、岩槻政晃、馬場祥史、坂本快郎、吉田直矢、平川弘聖、馬場秀夫、Patrick Tan
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] Verification of mechanism that CSC markers are implicated in poor prognosis for pancreatic ductal adenocarcinoma.2016
- Author(s)
  Arima K, Ishimoto T, Ohmuraya M, Okabe H, Kitano Y, Yamamura K, Kaida T, Nakagawa S, Imai K, Hashimoto D, Chikamoto A, Yamashita Y, Baba H
- Organizer
  ESMO-ASIA 2016
- Place of Presentation
  シンガポール
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15595
[Presentation] Helicobacter pylori Infection causes gastric cancer initiation and progression via miR-328/CD44 signaling.2015
- Author(s)
  Keisuke Miyake、Takatsugu Ishimoto, Hidetaka Sugihara, Kojiro Eto, Daisuke Izumi, Junji Kurashige, Yukiharu Hiyoshi, Shiro Iwagami, Yoshifumi Baba, Yuji Miyamoto, Naoya Yoshida, Hideo Baba.
- Organizer
  AACR Annual Meeting 2015
- Place of Presentation
  Pennsylvania Convention Center（米国・フィラデルフィア）
- Year and Date
  2015-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293290
[Presentation] Near T4食道癌に対する化学放射線療法および手術の治療成績2015
- Author(s)
  吉田直矢、馬場祥史、日吉幸晴、井田智、岩上志朗、藏重淳二、坂本快郎、宮本裕士、石本崇胤、辛島龍一、原田和人、江藤弘二郎、杉原栄孝、泉大輔、小澄敬祐、徳永竜馬、清住雄希、中村健一、大内繭子、渡邊雅之、馬場秀夫
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-24591950
[Presentation] 消化器癌におけるmicroRNAを介したCD44発現制御の解明2013
- Author(s)
  石本崇胤、渡邊　雅之、辛島　龍一、今村　裕、岩上　志朗、馬場　祥史、坂本　快郎、宮本　裕士、吉田　直矢、馬場　秀夫
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24591950
[Presentation] CD44 expression via miR-328 suppression in Helicobacter pylori infected gastric mucosa causes cancer initiation and progression2013
- Author(s)
  石本　崇胤
- Organizer
  国際胃がん学会(IGCC) 2013
- Place of Presentation
  イタリア・ベローナ
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] Hypomethylation of the IGF2 DMR0 in Esophageal Squamous Cell Carcinoma, Detected by Bisulfite Pyrosequencing, is Associated with Poor Prognosis2013
- Author(s)
  Murata A, Baba Y, Watanabe M, Shigaki H, Miyake K, Ozaki N, Ishimoto T, Iwatsuki M, Iwagami S, Sakamoto Y, Miyamoto Y, Yoshida N, Baba H
- Organizer
  9th AACR-Japanese Cancer Association Joint Conference (AACR-JCA)
- Place of Presentation
  Hyatt Regency Maui, Hawaii
- Year and Date
  2013-02-23
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] Association of IGF2 DMR0 hypomethylation in esophageal squamous cell carcinoma with poor prognosis.2013
- Author(s)
  Yoshifumi Baba, Masayuki Watanabe, Asuka Murata, Hironobu Shigaki, Shiro Iwagami, Takatsugu Ishimoto, Hideo Baba
- Organizer
  ASCO 2013
- Place of Presentation
  Chicago(アメリカ)
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] Novel discovery of miR-30e* regulating Bmi1 expression mediated by tumor-associated macrophages in gastric cancer.2013
- Author(s)
  Hidetaka Sugihara、Takatsugu Ishimoto, Daisuke Izumi, Hiroshi Sawayama, Yu Imamura, Satoshi Ida, Shiro Iwagami,Yoshifumi Baba,Yasuo Sakamoto,Yuji Miyamoto,Naoya Yoshida,Hideo Baba
- Organizer
  The 4th JCA-AACR
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24591950
[Presentation] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in gastrointestinal cancer cells and promote redox adaptation2013
- Author(s)
  石本　崇胤
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  ワシントン
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 食道癌におけるLINE-1メチル化レベルとDNAコピー数異常の関係2013
- Author(s)
  馬場祥史、渡邊雅之、村田飛鳥、志垣博信、岩上志朗、石本崇胤、岩槻政晃、吉田直矢、馬場秀夫
- Organizer
  第24回日本消化器癌発生学会
- Place of Presentation
  石川県立音楽堂
- Year and Date
  2013-09-05
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 消化器癌幹細胞におけるCD44の機能的役割と発現制御2013
- Author(s)
  石本　崇胤
- Organizer
  第113回日本外科学会
- Place of Presentation
  マリンメッセ福岡
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 食道扁平上皮癌におけるLINE-1低メチル化とDNAコピー数異常、CDK6増幅の関係2013
- Author(s)
  馬場祥史、渡邊雅之、村田飛鳥、志垣博信、三宅慧輔、石本崇胤、岩槻政晃、岩上志朗、吉田直矢、馬場秀夫
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] A novel gene-pathway regulating of microRNA mediates resistance to trastuzumab for gastric cancer2013
- Author(s)
  Kojiro Eto、Masayuki Watanabe, Masaaki Iwatsuki, Takatsugu Ishimoto, Hideo Baba
- Organizer
  The 4th JCA-AACR
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24591950
[Presentation] 食道扁平上皮癌におけるIGF2 DMR0メチル化レベルと予後の関係2013
- Author(s)
  村田飛鳥、馬場祥史、渡邊雅之、志垣博信、石本崇胤、岩槻政晃、尾崎宣之、岩上志朗、坂本快郎、宮本裕士、吉田直矢、馬場秀夫
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  マリンメッセ福岡
- Year and Date
  2013-04-13
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 同時性・異時性頭頚部癌を有する食道癌症例におけるLINE-1メチル化レベル2013
- Author(s)
  馬場祥史、渡邊雅之、吉田直矢、小澄敬祐、原田和人、村田飛鳥、岩上志朗、辛島龍一、石本崇胤、馬場秀夫
- Organizer
  第65回日本気管食道学会総会ならびに学術講演会
- Place of Presentation
  品川プリンスホテル(東京都)
- Year and Date
  2013-11-01
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] Relationship between LINE-1 methylation level, allelic imbalance and PIK3CA mutation in esophageal squamous cell carcinoma2013
- Author(s)
  Baba Y, Watanabe M, Murata A, Shigaki H, Iwagami S, Iwatsuki M, Ishimoto T, Baba H
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington, DC, USA
- Year and Date
  2013-04-09
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 食道癌に対する術前DCF 療法の有用性と今後の展望2013
- Author(s)
  渡邊雅之、馬場祥史、吉田直矢、石本崇胤、尾崎宣之、日吉幸晴、岩上志朗、岩槻政晃、坂本快郎、宮本裕士、馬場秀夫
- Organizer
  第113回日本外科学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24591950
[Presentation] 消化器癌において癌幹細胞マーカーを制御するmicroRNAの同定と機能解析2013
- Author(s)
  石本　崇胤
- Organizer
  第68回日本消化器外科学会
- Place of Presentation
  宮崎・シーガイヤコンベンションセンター
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] Association of IGF2 DMR0 hypomethylation in esophageal squamous cell carcinoma with poor prognosis2013
- Author(s)
  Baba Y, Watanabe M, Murata A, Shigaki H, Iwagami S, Ishimoto T, Baba H
- Organizer
  2013 ASCO Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-24659617
[Presentation] 消化器癌におけるmicroRNAを介したCD44発現制御の解明2013
- Author(s)
  石本　崇胤
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 治療抵抗性がん癌幹細胞に対する新しい治療戦略2012
- Author(s)
  石本　崇胤
- Organizer
  第112回日本外科学会定期学術集会
- Place of Presentation
  幕張メッセ国際会議場
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 腫瘍微小環境における癌幹細胞マーカーの発現制御2012
- Author(s)
  石本　崇胤
- Organizer
  第67回日本消化器外科学会
- Place of Presentation
  富山県民会館
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 消化器癌における酸化ストレス抵抗性を獲得する分子メカニズム2012
- Author(s)
  石本　崇胤
- Organizer
  2012年度日本消化器関連学会週間（JDDW 2012）
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 消化器癌における癌幹細胞マーカー発現制御機構の解明2012
- Author(s)
  石本　崇胤
- Organizer
  第23回日本消化器癌発生学会
- Place of Presentation
  徳島県鳴門市ルネッサンスリゾートナルト
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] 消化器癌におけるCD44発現制御機構を標的とした治療戦略
- Author(s)
  石本崇胤
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  京都
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in gastrointestinal cancer cells and promote redox adaptation
- Author(s)
  Ishimoto T
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, California
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24591912
[Presentation] Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in gastrointestinal cancer cells and promote redox adaptation
- Author(s)
  Ishimoto T
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, California
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25461984

1. IWATSUKI Masaaki (50452777)

# of Collaborated Projects: 10 results

# of Collaborated Products: 11 results
2. BABA Yoshifumi (20599708)

# of Collaborated Projects: 8 results

# of Collaborated Products: 67 results
3. Yasuda Tadahito (00867947)

# of Collaborated Projects: 6 results

# of Collaborated Products: 15 results
4. 今村裕 (70583045)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
5. Msayuki Watanabe (80254639)

# of Collaborated Projects: 5 results

# of Collaborated Products: 16 results
6. BABA Hideo (20240905)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
7. Fukuda Masahiro (60802113)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. Miyamoto Yuji (80551259)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
9. Miyake Keisuke (10814759)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
10. Arima Kota (10792616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
11. 小澄敬祐 (50594884)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
12. 藏重淳二 (90594474)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
13. 原田和人 (70608869)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
14. ETO Kojiro

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
15. Ohmuraya Masaki (60398229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
16. Hdetaka Sugihara (10608863)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
17. HAYASHI Naoko (20452899)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. BEPPU Toru (70301372)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
19. SAKAMOTO Yasuo (00452897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
20. 今井克憲 (60555746)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
21. 美馬浩介 (00546559)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
22. 内原智幸 (60835172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
23. 千場隆 (30897682)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
24. KINOSHITA Kouichi (10507792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HIRASHIMA Koutarou (10594468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. IWAGAMI Shiro (70530153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
27. Hiyoshi Yukiharu (30573612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. OZAKI Nobuyuki (40551255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. HASHIMOTO Daisuke (80508507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. NITTA Hidetoshi (90555749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Nagai Youhei (30551254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
32. Hayashi Hiromitsu (80625773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
33. Sawayama Hiroshi (40594875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
34. 吉田直矢 (60467983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
35. 泉大輔 (60594877)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
36. 日比泰造 (10338072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 山下洋市 (00404070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 中川茂樹 (10594872)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 清住雄希 (30827324)

# of Collaborated Projects: 1 results

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40. 須田年生 (60118453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
41. 中島雄太 (70574341)

# of Collaborated Projects: 1 results

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42. 北村裕介 (80433019)

# of Collaborated Projects: 1 results

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43. 北村文優 (90897068)

# of Collaborated Projects: 1 results

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44. 三森功士 (50322748)

# of Collaborated Projects: 1 results

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45. Sheng Guojun (20399439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 黒滝大翼 (10568455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. 付凌峰 (40973730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. TANAKA Yohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. SHIGAKI Hironobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. CHIKAMOTO Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. TOKUNAGA Ryuma

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. TAKAMORI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 中尾光善

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
54. 梅本晃正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
55. 岡部弘尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
56. 井田智

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
57. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 岡崎章悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
59. 大西紘二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
60. 山崎淳太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
61. 三河拓己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIMOTO Takatsugu 石本 崇胤

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オプトジェネティクス技術を用いた腫瘍微小環境制御の可能性を拓くPrincipal Investigator

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ストローマル・リプログラミングを軸としたがん治療戦略の開発Principal Investigator

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腫瘍間質に依存したシェアストレス抵抗性の獲得と血行性がん転移機構の解明Principal Investigator

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Elucidation of circulating cluster niche for hematogenous metastasisPrincipal Investigator

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Elucidation of diversity and therapeutic target in scirrhous gastric cancer stromaPrincipal Investigator

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ISHIMOTO Takatsugu 石本崇胤