TODA HIROYUKI 戸田裕之

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TODA Hiroyuki 戸田裕之

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Researcher Number	00610677
Other IDs
Affiliation (Current)	2025: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 精神科学, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 精神科学, 准教授 2022 – 2023: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 精神科学, 教授 2017 – 2019: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究施設、病院並びに防衛, 精神科学, 講師 2017: 防衛医科大学校, 医学部, 助教 2017: 防衛医科大学校, 精神科, 講師 … More 2016: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 精神科学, 助教 2014 – 2015: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, その他部局等, 助教 2014: 防衛医科大学校, その他の部局等, 助教 2012 – 2013: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Psychiatric science Except Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related / Basic Section 58010:Medical management and medical sociology-related / Basic Section 10040:Experimental psychology-related / Basic Section 58080:Gerontological nursing and community health nursing-related / Basic Section 51020:Cognitive and brain science-related / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 母子分離ストレス / エピジェネティクス / ストレス応答回路 / 虐待 / サイトカイン / FKBP5 / PTSD / 心的外傷後ストレス障害 / DNAメチル化修飾制御 / CRISPR/dCas9 … More / 交通外傷 / HPA系 / ストレス応答制御機構 / 気分障害 / 視床下部‐下垂体‐副腎系 / マイクログリア / 幼少期ストレス / Early Life Stress / 遺伝環境相互作用 / 遺伝子多型 / メチル化 / うつ病 / 双極性障害 / BDNF / 学習性無力 / 拘束ストレス / 母子分子ストレス / 神経栄養因子 / 環境富化 / 再固定 / 消去 / 恐怖記憶 / 不安 / 恐怖条件付け / エピジェネティック / 恐怖条件付けモデル / 扁桃体 / ニューロテンシン … More Except Principal Investigator うつ病 / PTSD / VR / 皮質 / fMRI / 恐怖記憶 / BDNF / depression / autophagy / antidepressant / stress / 二次的外傷性ストレス / 共感満足 / バーンアウト / 共感疲労 / 医療従事者 / 共感性 / 事故記憶 / モーションキャプチャ / EEG / 脳イメージング / トラウマ記憶 / 感覚 / 尺度 / 慢性・反復性うつ / 否定的生育環境 / アセスメント尺度 / ACE / 情動調整不全 / 解離 / 慢性・反復性のうつ / 生育歴的なトラウマ / 視覚野 / 記憶 / 知覚 / 恐怖 / 脳構造 / 皮質メカニズム / モーショントラック / 視覚 / トラウマ / 身体運動 / 感覚野 / 皮質感覚野 / 心的トラウマ / 抑うつ症状 / 炎症 / ミクログリア / アストロサイト / エンドトキシン耐性 / リポ多糖 / マイクログリア / 脳組織 / 血漿 / L体 / D体 / アミノ酸 / うつ病モデルマウス / L体アミノ酸 / 血液 / モデル動物 / D体アミノ酸 / 海馬 / miRNA / 母子分離ストレス / DNMT / 成体海馬神経細胞新生 / DNAメチル化 / 幼少期ストレス / 整体情報・計測 / 大うつ病 / モニタリング / 生体情報・計測 / 認知症 / パーキンソン病 / 双極性障害 / 音声病態分析 / hippocampal region / membrane trafficking / neural plasticity / stress resilience / 電気けいれん療法 / lipid raft / hippocampus / ECT / TrkB / endocytosis / 細胞死 / 抗うつ薬 / アポトーシス / VEGF / オートファジー / ストレス / neurotrophic factor Less

個人の共感特性を踏まえた医療者に対する共感性教育の効果検証
- Principal Investigator
  
  長峯正典
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  National Defense Medical College
ACEを背景にもつ難治性うつの発達経路の検討とその簡易スクリーニング法の現場実装
- Principal Investigator
  
  田辺肇
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Shizuoka University
皮質可塑性におけるトラウマ記憶の長期固定化機序の実験的検証
- Principal Investigator
  
  小泉愛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 10040:Experimental psychology-related
- Research Institution
  Sony Computer Science Laboratories, Inc. (Research Lab.)
Exploring the mechanisms through which stress encountered in the developmental stages affects the modulation of stress responses in PTSD.Principal Investigator
- Principal Investigator
  
  戸田裕之
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
リポ多糖の前投与がミクログリアを介した抑うつ症状の発症を抑制するメカニズムの研究
- Principal Investigator
  
  古賀農人
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
Reserach of depression focusing on D-amino acids
- Principal Investigator
  
  NUMATA Shusuke
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  The University of Tokushima
Effects of developmental stress exposure on stress response regulation in depression and bipolar disorderPrincipal Investigator
- Principal Investigator
  
  Hiroyuki Toda
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  National Defense Medical College
Fear memory formation mechanisms in sensory cortices.
- Principal Investigator
  
  KOIZUMI Ai
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Keio University
The effect of gene-environmental interactions on PTSDPrincipal Investigator
- Principal Investigator
  
  Toda Hiroyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  National Defense Medical College
Alteration of autophagy signaling in the brain by psychiatric treatments
- Principal Investigator
  
  NIBUYA Masashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Tohoku Medical and Pharmaceutical University
  National Defense Medical College
Development of Technology for Therapeutic Effect Follow-up by Voice Pathophysiological Analyzing
- Principal Investigator
  
  TOKUNO Shinichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  The University of Tokyo
Epigenetic effects of early life stress on adult hippocampal neurogenesis
- Principal Investigator
  
  Boku Shuken
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Kobe University
Neuronal Cellular Response to Behavioral Stress
- Principal Investigator
  
  NIBUYA Masashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  National Defense Medical College
Molecular mechanisms of the enhancement of conditioned fear memory induced by maternal separationPrincipal Investigator
- Principal Investigator
  
  TODA Hiroyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  National Defense Medical College

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2011 2010 2009

All Journal Article Presentation

[Journal Article] Impact of dysfunctional parenting, affective temperaments, and stressful life events on the development of melancholic and non-melancholic depression: A path analysis study2023
- Author(s)
  Tamada Yu、Inoue Takeshi、Sekine Atsushi、Toda Hiroyuki、Takeshima Minoru、Sasaki Masaaki、Fujimura Yota、Ohmae Susumu
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 11 Pages: e0294070-e0294070
- DOI
  10.1371/journal.pone.0294070
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K03116, KAKENHI-PROJECT-22K11227
[Journal Article] Affective temperaments mediate the effect of childhood maltreatment on bipolar depression severity.2023
- Author(s)
  Terao,I., Morishita,C., Tamada,Y., Masuya,J., Fujimura,Y., Toda,H., Kusumi,I., Tanabe,H., & Inoue,T.
- Journal Title
  
  Psychiatry and Clinical Neurosciences Reports
  
  Volume: 2 Issue: 2
- DOI
  10.1002/pcn5.94
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K04200, KAKENHI-PROJECT-23K12900, KAKENHI-PROJECT-22K11227, KAKENHI-PROJECT-22H00071, KAKENHI-PROJECT-23K24266
[Journal Article] Identifying factors related to stigma toward psychiatric illness and mental health services and attitudes of help-seeking among Japan Ground Self-Defense Force members.2023
- Author(s)
  Yamazaki M, Nagamine M, Kitano M, Waki F, Edo N, Koga M, Tachimori H, Toda H.
- Journal Title
  
  J Psychiatr Res.
  
  Volume: 165 Pages: 241-247
- DOI
  10.1016/j.jpsychires.2023.07.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K11227, KAKENHI-PROJECT-23K24266
[Journal Article] Event-related PTSD symptoms as a high-risk factor for suicide: longitudinal observational study.2023
- Author(s)
  Chiba, T., Ide, K., Murakami, M. … Toda, H.…他13名
- Journal Title
  
  Nat. Mental Health
  
  Volume: 1 Issue: 12 Pages: 1013-1022
- DOI
  10.1038/s44220-023-00157-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11227, KAKENHI-PROJECT-23K24266
[Journal Article] 双極性障害における不安2022
- Author(s)
  戸田裕之
- Journal Title
  
  臨床精神医学
  
  Volume: 51 Pages: 1029-1035
- Data Source
  KAKENHI-PROJECT-22K11227
[Journal Article] A reciprocal inhibition model of alternations between non-dissociative and dissociative states in patients with PTSD2021
- Author(s)
  Chiba, T., Ide, K., Boku, S., Taylor, J.E., Ph.D., Toda, H., Kanazawa, T., Kato, S., Horiuchi, Y. Hishimoto, A., Maruyama, T. Yamamoto, T., Shirakawa, M., Sora, I., Kawato, M., and ＊Koizumi, A.
- Journal Title
  
  Molecular Psychiatry
  
  Volume: 26 Issue: 9 Pages: 5023-5039
- DOI
  10.1038/s41380-020-0827-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02714
[Journal Article] Effect of interaction between a specific subtype of child abuse and the FKBP5 rs1360780 SNP on DNA methylation among patients with bipolar disorder2020
- Author(s)
  Saito Taku、Shinozaki Gen、Koga Minori、Tanichi Masaaki、Takeshita Shogo、Nakagawa Ryuichi、Nagamine Masanori、Cho Hyunkeun R.、Morimoto Yuji、Kobayashi Yasushi、Yoshino Aihide、Toda Hiroyuki
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 272 Pages: 417-422
- DOI
  10.1016/j.jad.2020.03.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07617
[Journal Article] Relationship between the subtypes of child abuse and affective temperaments: Comparison of depression and bipolar disorder patients and healthy controls using the reclassified Child Abuse and Trauma Scale2019
- Author(s)
  Saito Taku、Toda Hiroyuki、Inoue Takeshi、Koga Minori、Tanichi Masaaki、Takeshita Shogo、Nakagawa Ryuichi、Nagamine Masanori、Masuya Jiro、Tanabe Hajime、Shimizu Kunio、Kusumi Ichiro、Yoshino Aihide
- Journal Title
  
  Journal of Affective Disorders
  
  Volume: 257 Pages: 396-403
- DOI
  10.1016/j.jad.2019.06.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07617
[Journal Article] Maternal separation enhances conditioned fear and decreases the mRNA levels of the neurotensin receptor 1 gene with hypermethylation of this gene in the rat amygdala2016
- Author(s)
  Hiroyuki Toda, Shuken Boku, Shin Nakagawa, Takeshi Inoue, Akiko Kato, Naoki Takamura, Ning Song, Masashi Nibuya, Tsukasa Koyama, Ichiro Kusumi
- Journal Title
  
  PLOS ONE
  
  Volume: in press
- NAID
  120005537461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791248
[Journal Article] Increased Expression of Endocytosis-Related Proteins in Rat Hippocampus Following 10-Day Electroconvulsive Seizure Treatment.2016
- Author(s)
  Enomoto S, Shimizu K, Nibuya M, Toda H, Yoshino A, Suzuki E, Kondo T, Fukuda H
- Journal Title
  
  Neurosci Lett
  
  Volume: in press Pages: 85-91
- DOI
  10.1016/j.neulet.2016.05.015
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09816
[Journal Article] The structural equation analysis of childhood abuse, adult stressful life events, and temperaments in major depressive disorders and their influence on refractoriness. Neuropsychiatr Dis Treat.2015
- Author(s)
  Toda H, Inoue T, Tsunoda T, Nakai Y, Tanichi M, Tanaka T, Hashimoto N, Nakato Y, Nakagawa S, Kitaichi Y, Mitsui N, Boku S, Tanabe H, Nibuya M, Yoshino A, Kusumi I.
- Journal Title
  
  Neuropsychiatr Dis Treat
  
  Volume: 11 Pages: 2079-90
- DOI
  10.2147/ndt.s82236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09816, KAKENHI-PROJECT-24530862
[Journal Article] Affective temperaments play an important role in the relationship between childhood abuse and depressive symptoms in major depressive disorder.2015
- Author(s)
  Toda H, Inoue T, Tsunoda T, Nakai Y, Tanichi M, Tanaka T, Hashimoto N, Takaesu Y, Nakagawa S, Kitaichi Y, Boku S, Tanabe H, Nibuya M, Yoshino A, Kusumi I.
- Journal Title
  
  Psychiatry Res
  
  Volume: 236 Pages: 142-7
- DOI
  10.1016/j.psychres.2015.12.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09816
[Journal Article] Electroconvulsive seizures enhance autophagy signaling in rat hippocampus.2014
- Author(s)
  Otabe H, Nibuya M* Shimazaki K, Toda H, Suzuki G, Nomura S, Shimizu K.
- Journal Title
  
  Prog Neuropsychopharmacol Biol Psychiatry
  
  Volume: 50 Pages: 37-43
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591690
[Journal Article] Environmental enrichment enhances autophagy signaling in the rat hippocampus.2014
- Author(s)
  Takahashi T, Shimizu K, Shimazaki K, Toda H, Nibuya M
- Journal Title
  
  Brain Res
  
  Volume: 1592 Pages: 113-123
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24591690
[Journal Article] Maternal Separation Enhances Conditioned Fear and Decreases the mRNA Levels of the Neurotensin Receptor 1 Gene with Hypermethylation of This Gene in the Rat Amygdala2014
- Author(s)
  Hiroyuki Toda, Shuken Boku, Shin Nakagawa, Takeshi Inoue, Akiko Kato, Naoki Takamura, Ning Song, Masashi Nibuya, Tsukasa Koyama, Ichiro Kusumi
- Journal Title
  
  PLoS One
  
  Volume: 15
- NAID
  120005537461
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791248
[Journal Article] DNA methylation of neurotensin receptor1 gene in amygdala induced by maternal separation enhances conditioned fear in adult rats.2014
- Author(s)
  Toda H, Boku S, Nakagawa S, Inoue T, Kato A, Takamura N, Song N, Nibuya M, Koyama T, Kusumi I
- Journal Title
  
  PLoS One
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591690
[Journal Article] Maternal separation enhances conditioned fear and decreased the mRNA levels of the neurotensin receptor 1 gene with hypermethylation of this gene in the rat amygdala.2014
- Author(s)
  Toda H, Boku S, Nakagawa S, Inoue T, Kato A, Takamura N, Song N, Nibuya M, Koyama T, Kusumi I
- Journal Title
  
  PLos One
  
  Volume: 9
- NAID
  120005537461
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591690
[Presentation] PTSDと不安障害の生物学的な基盤の共通性あるいは異同2023
- Author(s)
  戸田裕之
- Organizer
  第 22 回日本トラウマティック・ストレス学会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 恐怖記憶の記憶形成の初期段階にはミクログリアは必須ではない2023
- Author(s)
  佐藤真有実, 古賀農人, 中川隆一, 長峯正典, 浅井史穂, 太田宏之, 戸田裕之, 吉野相英
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 神経炎症由来の精神障害に対するエンドトキシン耐性誘導による発症抑制効果におけるミクログリアの寄与2023
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 佐藤真有実, 長峯正典, 木下学, 中島弘幸, 浅井史穂, 茂木美千子, 吉野相英
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 軽度外傷性脳損傷は心理的ストレスに対する精神障害発症の脆弱性を亢進する2023
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 佐藤真有実, 長峯正典, 佐藤泰司, 木下学, 浅井史穂, 吉野相英
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 自衛官の精神疾患に対するスティグマの調査2023
- Author(s)
  山崎真之, 戸田裕之, 長峯正典, 北野誠人, 脇文子, 江戸直樹, 古賀農人, 立森久照, 吉野相英
- Organizer
  第 119 回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 食餌時間制限による減量では高脂質食摂取による不安様行動の発生が抑制されない2023
- Author(s)
  篠崎正紀, 戸田裕之, 浅井史穂, 吉野相英, 古賀農人
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 交通外傷後に高ストレスを呈した3例の報告と,そこから見えるPICSの課題についての考察2023
- Author(s)
  寺山毅郎, 戸田裕之, 吉野相英
- Organizer
  第50回日本集中治療医学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] Preconditioning of Lipopolysaccharide Improves Anxiety-Like Behavior and Brain Inflammation Associated with Chronic Corticosterone Exposure in Mice2023
- Author(s)
  Nakagawa R, Toda H, Koga M, Sato M, Nagamine M, Yoshino A
- Organizer
  2023SOBP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] Inhibitory effect of preconditioning with lipopolysaccharide on the onset of anxiety and depressive-like behaviors2023
- Author(s)
  Koga M, Toda H, Nagamine M, Kinoshita M, Nakagawa R, Sato M, Mitsui Y, Yoshino A
- Organizer
  2023SOBP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 慢性コルチコステロン暴露モデルマウスにおける中枢神経マクロファージの表現型の変化2023
- Author(s)
  中川隆一, 戸田裕之, 古賀農人, 長峯正典, 中島弘幸, 木下学, 佐藤真有美, 浅井史穂, 吉野相英
- Organizer
  第45回日本生物学的精神医学会総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 東日本大震災に派遣された陸上自衛官の心的外傷後ストレス症状の軌跡とその関連要因－7年間の縦断研究－2023
- Author(s)
  斉藤拓, 戸田裕之, 古賀農人, 長峯正典
- Organizer
  第 22 回日本トラウマティック・ストレス学会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 小児期被虐待経験が双極性うつ病のうつ症状の重症度に及ぼす影響を感情気質の増強が媒介する2022
- Author(s)
  寺尾樹, 森下千尋, 戸田裕之, 井上猛
- Organizer
  第19 回日本うつ病学会総会第5 回日本うつ病リワーク協会年次大会
- Data Source
  KAKENHI-PROJECT-22K11227
[Presentation] 小児期被虐待経験が双極性うつ病のうつ症状の重症度に及ぼす影響を感情気質の増強が媒介する．2022
- Author(s)
  寺尾樹，森下千尋，戸田裕之，井上猛
- Organizer
  第19回日本うつ病学会総会
- Data Source
  KAKENHI-PROJECT-22K11227
[Presentation] Effects of CSF1R inhibitor PLX3397 on reinforcement learning ability2022
- Author(s)
  太田裕之, 古賀農人, 中川隆一, 戸田裕之, 石塚俊晶
- Organizer
  第 95 回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] Psychological and traumatic stress and the risk of developing diabetes and psychiatric disorders after a disaster-relief mission2022
- Author(s)
  田中徹平, 竹下昇吾, 井上猛, 吉野相英, 澤村岳人, 戸田裕之
- Organizer
  第118 回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-22K11227
[Presentation] Psychological and traumatic stress and the risk of developing diabetes and psychiatric disorders after a disaster relief mission2022
- Author(s)
  田中徹平, 竹下昇吾, 井上猛, 吉野相英, 澤村岳人, 戸田裕之
- Organizer
  第 118 回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安症状の病態形成においてマイクログリアは正にも負にも寄与する2022
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 佐藤真有実, 長峯正典, 浅井史穂, 三井由美, 吉野相英
- Organizer
  第 44 回日本生物学的精神医学会年会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安症状とマイクログリアの状態の関係2022
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 長峯正典, 浅井史穂, 三井由美, 吉野相英
- Organizer
  第 14 回日本不安症学会学術大会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] Trajectories of PTSD among First Responders after the 2011 Great East Japan Earthquake: a 7-year prospective cohort study2022
- Author(s)
  Van der Does F, Saito T, Nagamine M, Van der Wee N, Shigemura J, Yamamoto T, Takahashi Y, Koga M, Toda H, Yoshino A, Vermetten E, Giltay E:
- Organizer
  30th European Congress of Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 不安および抑うつ様行動発現に対する抑制効果を示すリポ多糖プレコンディショニングは脳内マクロファージの構成を変化させる2022
- Author(s)
  古賀農人, 戸田裕之, 中川隆一, 長峯正典, 中島弘幸, 木下学, 浅井史穂, 佐藤真有実, 松井茉莉江,三井由美, 吉野相英
- Organizer
  第 41 回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-23K24266
[Presentation] 水素の摂取は神経炎症が引き起こす興味・関心の低下を抑制する2021
- Author(s)
  古賀農人、佐藤真有実、徳野慎一、中川隆一、長峯正典、浅井史穂、戸田裕之、吉野相英
- Organizer
  第10回分子状水素医学生物学会
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] Lipopolysaccharideプレコンディショニングによる、マウスにおける慢性コルチコステロン暴露で認められる不安様行動、神経炎症の改善2021
- Author(s)
  中川隆一、古賀農人、佐藤真有実、戸田裕之、長峰正典、藤田真敬、吉野相英
- Organizer
  第43回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] 精神障害の病態モデルマウスを用いたマイクログリアの異常と精神障害発症との因果関係解明の検討2021
- Author(s)
  古賀農人、戸田裕之、中川隆一、佐藤真有実、長峯正典、浅井史穂、三井由美、吉野相英
- Organizer
  第40回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] 中枢神経系におけるエンドトキシン耐性のメカニズムの解明と炎症由来の精神障害発症予防への応用2021
- Author(s)
  古賀農人、戸田裕之、中川隆一、佐藤真有実、前沢友里、長峯正典、浅井史穂、三井由美、吉野相英
- Organizer
  第43回日本生物学的精神医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] 気質とメンタルヘルス　―虐待と気質―2020
- Author(s)
  戸田　裕之
- Organizer
  第116回日本精神神経学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Child Abuse and Trauma Scale (CATS) 再分類版の信頼性と妥当性ー気分障害患者及び健常者における検討－2020
- Author(s)
  斉藤　拓, 戸田　裕之, 井上　猛, 長峯　正典, 田辺　肇, 久住　一郎, 吉野　相英
- Organizer
  第19 回日本トラウマティック・ストレス学会
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] リポポリサッカリドの事前投与は炎症由来の精神症状発症を抑制する2020
- Author(s)
  古賀農人、戸田裕之、長峯正典、木下学、浅井史穂、三井由美、吉野相英
- Organizer
  第50回日本神経精神薬理学会・第42回日本生物学的精神医学会・第４回日本精神薬学会総会・学術集会（NPBPPP 2020 合同年会）
- Data Source
  KAKENHI-PROJECT-20K07958
[Presentation] これからのうつ病治療幼少期ストレスから考える治療2019
- Author(s)
  戸田裕之
- Organizer
  第16 回日本うつ病学会総会, 徳島
- Invited
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Effects of maternal separation stress on inflammatory cytokines in a rat model of post-traumatic stress disorder2019
- Author(s)
  Hiroyuki Toda, Masaaki Tanichi, Shinichi Tokuno, Shogo Takeshita, Masanori Nagamine, Kunio Shimizu, Aihided Yoshino
- Organizer
  Neuroscience 2019, Chicago
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] 幼少期ストレスは前頭前野のマイクログリアの質的変化ではなく数量的な変化を引き起こす2019
- Author(s)
  篠崎正紀, 梁木百合香, 古賀農人, 戸田裕之, 浅井史穂, 三井由美, 長峯正典, 吉野相英
- Organizer
  第38 回躁うつ病の薬理生化学的研究懇話会, 熱海
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] 双極性障害における幼少期ストレスとFKBP5 の一塩基多型、DNA メチル化との関係2019
- Author(s)
  斉藤拓, 戸田裕之, 古賀農人, 谷知正章, 竹下昇吾, 中川隆一, 長峯正典, 吉野相英
- Organizer
  第38 回躁うつ病の薬理生化学的研究懇話会, 熱海
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] 自発運動促進と感覚刺激増加はシャトル箱法PTSD モデルラットの神経栄養因子とFKBP5 のmRNA 発現に異なる影響をもたらす2018
- Author(s)
  谷知　正章, 戸田　裕之, 清水　邦夫, 古賀　農人, 斉藤　拓, 榎本　真悟, 朴　秀賢, 浅井　史穂, 三井　由美, 長峯　正典, 澤村　岳人, 藤田　真敬, 吉野　相英
- Organizer
  第37 回躁うつ病の薬理生化学的研究懇話
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] シンポジウム10 社会と個人の相互作用としての気分障害:養育環境との相互作用の観点から2018
- Author(s)
  戸田　裕之
- Organizer
  第15 回日本うつ病学会総会
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Immobilization stress enhances the hippocampal mRNA expression of FKBP5 in maternal separation rats2018
- Author(s)
  H. TODA, M. TANICHI, M. KOGA, T. SAITO, S. ENOMOTO, S. TAKESHITA, F. ASAI, Y. MITSUI, M. NAGAMINE, M. FUJITA, K. SHIMIZU, A. YOSHINO
- Organizer
  neuroscience 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] 環境富化されたシャトル箱法PTSD モテルラットの回避麻痺行動改善は、海馬の BDNF mRNA と正の相関を示す2018
- Author(s)
  谷知正章, 戸田裕之, 清水邦夫, 斉藤拓, 浅井史穂, 三井由美, 榎本真悟, 長峯正典, 吉野相英
- Organizer
  第63 回防衛衛生学会
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] うつ病患者におけるFKBP5 遺伝子多型と幼少期ストレス、気質、抑うつ症状との関連2018
- Author(s)
  斉藤　拓, 戸田　裕之, 谷知　正章, 竹下　昇吾, 浅井　史穂, 三井　由美, 長峯　正典, 清水　邦夫, 吉野　相英
- Organizer
  第15 回日本うつ病学会総会
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Impacts on the stress reactivity in adult rats of maternal separation as early life stress2018
- Author(s)
  M. TANICHI, H. TODA, M. KOGA, T. SAITO, S. ENOMOTO, F. ASAI, Y. MITSUI, M. NAGAMINE, K. SHIMIZU, A. YOSHINO
- Organizer
  WFSBP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] シンポジウム26:精神疾患の新しい創薬ターゲットを多角的に考察する:幼少期のストレスのストレス応答回路に与える影響から創薬を考える2018
- Author(s)
  戸田　裕之
- Organizer
  第114 回日本精神神経学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07617
[Presentation] Feasibility study of classifying major depressive disorder and bipolar disorders using voice features2017
- Author(s)
  Nakamura M, Omiya Y, Shinohara S, Mitsuyoshi S, Higuchi M, Hagiwara N, Takano T, Toda T, Saito T, Tanichi M, Yoshino A, Tokuno S
- Organizer
  XVII World Congress of Psychiatry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03002
[Presentation] Major depression index derived from the relationship between hurst exponent and zero crossing rate in voice2017
- Author(s)
  Shinohara S, Omiya Y, Nakamura M, Higuchi M, Hagiwara N, Takano T, Toda H , Saito T , Tanichi M , Yoshino A, Mitsuyoshi S, Tokuno S
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03002
[Presentation] 新しい創薬ターゲットを多角的に考察する:幼少期ストレスの観点から創薬は可能か?2017
- Author(s)
  戸田裕之
- Organizer
  第27 回日本臨床精神神経薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] 幼少期のネグレクト体験が、成人期のトラウマ体験による抑うつ反応を増強する2017
- Author(s)
  谷知正章, 戸田裕之, 斉藤拓, 榎本真悟, 長峯正典, 重村淳, 清水邦夫, 吉野相英
- Organizer
  第16 回日本トラウマティックストレス学会
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] シャトル箱法による PTSD モデルラットに学習性無力様行動変化をもたらした、母子分離ストレスの炎症性サイトカインに与える影響2017
- Author(s)
  谷知正章, 戸田裕之, 榎本真悟, 斉藤拓, 浅井史穂, 三井由美, 長峯正典, 徳野慎一, 清水邦夫, 吉野相英
- Organizer
  第39 回日本生物学的精神医学会第47 回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] 母子分離ストレスが成獣後のストレス反応性に及ぼす影響2017
- Author(s)
  谷知正章, 戸田裕之, 斉藤拓, 榎本真悟, 浅井史穂, 三井由美, 澤村岳人, 長峯正典, 藤田真敬, 清水邦夫, 吉野相英
- Organizer
  第36 回躁うつ病の薬理生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] 陸上自衛隊における新入隊員の音声によるストレス計測の試み2017
- Author(s)
  大宮康宏、萩原直樹、中村　光晃、篠原修二、樋口政和、光吉俊二、戸田裕之、長川真治、徳野慎一
- Organizer
  第90回日本産業衛生学会
- Data Source
  KAKENHI-PROJECT-15H03002
[Presentation] シャトル箱法によるPTSDモデルラットに対して母子分離ストレスが及ぼす行動と海馬のBDNF mRNA発現量への影響2016
- Author(s)
  谷知正章, 戸田裕之, 清水邦夫, 榎本真悟, 長峯正典, 丹生谷正史, 吉野相英
- Organizer
  第46回日本神経薬理学会年会
- Place of Presentation
  ソウル
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] Alternation of fundamental frequency of ultrasonic vocalizations by neonatal rats in response to distance from their mother2016
- Author(s)
  Nakamura M, Tanichi M, Toda H, Mitsuyoshi S. Shinohara S, Omiya Y, Shimizu K, Yoshino A, Tokuno S
- Organizer
  Neuroscience 2016
- Place of Presentation
  San Diego
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H03002
[Presentation] Learned helplessness induced by maternal separation of an animal model of PTSD using a shuttle box in rats and levels of BDNF in the hippocampus and the medial prefrontal cortex2016
- Author(s)
  Tanichi Masaaki, Toda Hiroyuki, Enomoto Shingo, Shimizu Kunio, Nagamine Masanori, Saito Taku, Uenoyama Maki, Aihide Yoshino
- Organizer
  Neuroscinece 2016
- Place of Presentation
  San Dieago
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] 母子分離ストレスはシャトル箱法によるPTSDモデルパラダイムにおける学習性無力行動を増強する2016
- Author(s)
  谷知　正章, 戸田　裕之, 清水　邦夫,榎本　真悟, 長峯　正典, 丹生谷　正史, 吉野　相英
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] トラウマに相当する逃避不能フットショック負荷前に実施した2週間の環境富化処置がシャトル箱法によるPTSDモデルラットに与える影響2016
- Author(s)
  清水　邦夫, 谷知　正章, 榎本　真悟, 戸田　裕之, 長峯　正典, 丹生谷　正史, 吉野　相英
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] シャトル箱法によるPTSDモデルラットに対して母子分離ストレスがもたらす学習性無力様の行動変化2016
- Author(s)
  谷知正章、清水邦夫、榎本真悟、戸田裕之、高橋知久、長峯正典、丹生谷正史、吉野相英
- Organizer
  第61回日本中央防衛衛生学会
- Place of Presentation
  東京
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] シャトル箱法によるPTSDモデルラットに対するEE処置におけるランニングホイールの役割2016
- Author(s)
  谷知正章, 清水邦夫, 榎本真悟, 戸田裕之, 高橋知久, 長峯正典, 丹生谷正史, 吉野相英
- Organizer
  第46回日本神経薬理学会年会
- Place of Presentation
  ソウル
- Year and Date
  2016-07-02
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] ランニングホイール玩具（自発運動量を促進する）を抜いた環境富化処置がシャトル箱法による心的外傷後ストレス障害モデルラットの特異な行動に与える影響2015
- Author(s)
  谷知正章、清水邦夫、榎本真吾、戸田裕之、高橋知久、長峯正典、丹生谷正史、吉野相英
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  東京
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] 母子分離ストレスがシャトル箱型行動解析システムにおけるラットの不安・抑うつ様行動に与える影響2015
- Author(s)
  谷知正章、榎本真悟、丹生谷正史、清水邦夫、戸田裕之、吉野相英
- Organizer
  第34回躁うつ病の薬理・生化学的研究懇話会
- Place of Presentation
  洲本
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] SPS（single prolonged stress）負荷ラットに対してシャトル箱を用いて測定した心的外傷後ストレス障害（PTSD）に類似する2方向性行動の解析2015
- Author(s)
  榎本真吾、清水邦夫、谷知正章、戸田裕之、高橋知久、長峯正典、丹生谷正史、吉野相英
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  東京
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] Impacts of maternal separation on an animal model of posttraumatic stress disorder using a shuttle box in rats2015
- Author(s)
  M TANICHI, H TODA, S ENOMOTO, K SHIMIZU, M UENOYAMA, Y MASUDA, R NAKAGAWA, M NIBUYA, A YOSHINO
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09815
[Presentation] Vulnerability to anxiety behavior induced by maternal separation stress may occur through the increase of DNA methylation at neurotensin type 1 receptor promoter region in rat amygdala2011
- Author(s)
  H Toda, S Nakagawa, S Boku, N Song, N Takamura, A Kato, T Inoue, T Koyama
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-24791248
[Presentation] Maternal separation stress and vulnerability to anxiety behavior in rats2010
- Author(s)
  H Toda, S Nakagawa, S Boku, Ning Song, N Takamura, A Kato, T Inoue, T Koyama
- Organizer
  International College of Neuropsychopharmacology
- Place of Presentation
  Houg Kong
- Data Source
  KAKENHI-PROJECT-24791248
[Presentation] Influence of early-life stress on behavior, HPA axis activity, gene expressions and hippocampal neurogenesis in adulthood rats2010
- Author(s)
  H Toda, S Nakagawa, S Boku, N Takamura, N Song, A Kato, T Inoue, T Koyama
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-24791248
[Presentation] Dexamethasone/corticotrophin releasing hormone test in maternal separation stress models2009
- Author(s)
  H Toda, S Nakagawa, S Boku, Ning Song, A Kato, T Inoue, T Koyama
- Organizer
  Neuroscience 2009
- Place of Presentation
  Cicago
- Data Source
  KAKENHI-PROJECT-24791248

1. 古賀農人 (70744936)

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TODA HIROYUKI 戸田 裕之

TODA Hiroyuki 戸田 裕之

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Exploring the mechanisms through which stress encountered in the developmental stages affects the modulation of stress responses in PTSD.Principal Investigator

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Effects of developmental stress exposure on stress response regulation in depression and bipolar disorderPrincipal Investigator

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The effect of gene-environmental interactions on PTSDPrincipal Investigator

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Molecular mechanisms of the enhancement of conditioned fear memory induced by maternal separationPrincipal Investigator

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[Journal Article] Impact of dysfunctional parenting, affective temperaments, and stressful life events on the development of melancholic and non-melancholic depression: A path analysis study2023

TODA HIROYUKI 戸田裕之

TODA Hiroyuki 戸田裕之