Hu Kuan 胡寛

Researcher Number	00827678
Other IDs	https://orcid.org/0000-0003-2448-2254
Affiliation (based on the past Project Information) *help	2021 – 2023: 国立研究開発法人量子科学技術研究開発機構, 量子医科学研究所先進核医学基盤研究部, 研究員 2019 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所先進核医学基盤研究部, 博士研究員(任常) 2018: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所標識薬剤開発部, 博士研究員(任常)
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related / 0902:General internal medicine and related fields Except Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator PET imaging / cancer / intracellular delivery / radionuclide therapy / 64Cu / intracellular protein / radiotheranostics / stapled peptide / Methionine / 18F bioconjugatoin … More / 18F labeling / ozaxiridine / PET tracer / Peptide / radiotracer / oxaziridine / ReACT / chemoselective / 18F-fluorination / methionine / diagnosis / PET / radiolabeling / fluorine 18 / peptide / PD-L1 / stabilized peptide … More Except Principal Investigator TRT治療 / PET診断 / mGluR1 / α線治療薬 / PET診断薬 / Radio-theranostics / 代謝型グルタミン酸受容体1型 / 膜貫通AMPA受容体調節性タンパク質 / オートラジオグラフィー / [11C]TARP-2105 / TARP-γ8 / オートラジオグラフィ / PET / 膜貫通AMPA受容体調節性タンパク質-γ8 / AMPA受容体 Less

Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapyPrincipal Investigator
- Principal Investigator
  
  胡寛
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Construction of a mGluR1-targeted radiotheranostic system for tumor-agnostic cancer treatment
- Principal Investigator
  
  Xie Lin
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Development of PET probes for gama 8-dependent transmembrane AMPA receptor regulatory protein
- Principal Investigator
  
  Zhang Ming-Rong
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Chemoselective methionine 18F-fluorination on unprotected peptides for positron-emission tomography imagingPrincipal Investigator
- Principal Investigator
  
  Hu Kuan
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Stabilized peptide targeting programmed death-ligand 1 for Positron Emission Tomography imaging and cancer immunotherapyPrincipal Investigator
- Principal Investigator
  
  胡寛
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0902:General internal medicine and related fields
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Preclinical Evaluation of Novel Positron Emission Tomography (PET) Probes for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2)2024
- Author(s)
  Chen Zhen、Chen Jiahui、Mori Wakana、Yi Yongjia、Rong Jian、Li Yinlong、Leon Erick R. Calderon、Shao Tuo、Song Zhendong、Yamasaki Tomoteru、Ishii Hideki、Zhang Yiding、Kokufuta Tomomi、Hu Kuan、Xie Lin、Josephson Lee、Van Richard、Shao Yihan、Factor Stewart、Zhang Ming-Rong、Liang Steven H.
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 67 Issue: 4 Pages: 2559-2569
- DOI
  10.1021/acs.jmedchem.3c01687
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-23K27558
[Journal Article] Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression2023
- Author(s)
  Zhang Lulu、Zhang Siqi、Wu Wenyu、Wang Xingkai、Shen Jieting、Wang Dongyuan、Hu Kuan、Zhang Ming-Rong、Wang Feng、Wang Rui
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 4 Issue: 192
- DOI
  10.3791/65047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] A 211At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy2023
- Author(s)
  Xie Lin、Zhang Lulu、Hu Kuan、Hanyu Masayuki、Zhang Yiding、Fujinaga Masayuki、Minegishi Katsuyuki、Ohkubo Takayuki、Nagatsu Kotaro、Jiang Cuiping、Shimokawa Takashi、Ashisuke Kazuma、Okonogi Noriyuki、Yamada Shigeru、Wang Feng、Wang Rui、Zhang Ming-Rong
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 4 Issue: 4 Pages: 100960-100960
- DOI
  10.1016/j.xcrm.2023.100960
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714, KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-23K27558
[Journal Article] Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging2023
- Author(s)
  Rong Jian、Yamasaki Tomoteru、Li Yinlong、Kumata Katsushi、Zhao Chunyu、Haider Ahmed、Chen Jiahui、Xiao Zhiwei、Fujinaga Masayuki、Hu Kuan、Mori Wakana、Zhang Yiding、Xie Lin、Zhou Xin、Collier Thomas L.、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 14 Issue: 10 Pages: 1419-1426
- DOI
  10.1021/acsmedchemlett.3c00320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-23K27558
[Journal Article] Linear Peptide-Based PET Tracers for Imaging PD-L1 in Tumors2023
- Author(s)
  Zhang Lulu、Zhang Siqi、Wu Jiang、Wang Yanrong、Wu Yuxuan、Sun Xiaona、Wang Xingkai、Shen Jieting、Xie Lin、Zhang Yiding、Zhang Hailong、Hu Kuan、Wang Feng、Wang Rui、Zhang Ming-Rong
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 20 Issue: 8 Pages: 4256-4267
- DOI
  10.1021/acs.molpharmaceut.3c00382
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-23K27558
[Journal Article] Small-animal PET study for noninvasive quantification of transmembrane AMPA receptor regulatory protein γ8 (TARP γ-8) in the brain2023
- Author(s)
  Yamasaki Tomoteru、Ishii Hideki、Hiraishi Atsuto、Kumata Katsushi、Wakizaka Hidekatsu、Zhang Yiding、Kurihara Yusuke、Ogawa Masanao、Nengaki Nobuki、Chen Jiahui、Li Yinlong、Liang Steven、Zhang Ming-Rong
- Journal Title
  
  Journal of Cerebral Blood Flow and Metabolism
  
  Volume: 43 Issue: 6 Pages: 893-904
- DOI
  10.1177/0271678x231152025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K08240, KAKENHI-PROJECT-23K27558
[Journal Article] A multifunctional nanotheranostic agent potentiates erlotinib to EGFR wild-type non-small cell lung cancer2022
- Author(s)
  Wang Duo、Zhou Jun、Fang Weimin、Huang Cuiqing、Chen Zerong、Fan Meng、Zhang Ming-Rong、Xiao Zeyu、Hu Kuan、Luo Liangping
- Journal Title
  
  Bioactive Materials
  
  Volume: 13 Pages: 312-323
- DOI
  10.1016/j.bioactmat.2021.10.046
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-19K24154
[Journal Article] Whole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors2022
- Author(s)
  Hu Kuan, Wu Wenyu, Xie Lin, Geng Hao, Zhang Yiding, Hanyu Masayuki, Zhang Lulu, Liu Yinghuan, Nagatsu Kotaro, Suzuki Hisashi, Guo Jialin, Wu Yundong, Li Zigang, Wang Feng, Zhang Ming-Rong
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: 12 Issue: 3 Pages: 1363-1376
- DOI
  10.1016/j.apsb.2021.09.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
[Journal Article] PEIGel: A biocompatible and injectable scaffold with innate immune adjuvanticity for synergized local immunotherapy2022
- Author(s)
  Xiao Zeyu、Wang Duo、Wang Chan、Chen Zerong、Huang Cuiqing、Yang Yuan、Xie Lin、Zhang Lulu、Xu Lingling、Zhang Ming-Rong、Hu Kuan、Li Zhou、Luo Liangping
- Journal Title
  
  Materials Today Bio
  
  Volume: 15 Pages: 100297-100297
- DOI
  10.1016/j.mtbio.2022.100297
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Journal Article] Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography2022
- Author(s)
  Yu Qingzhen、Kumata Katsushi、Rong Jian、Chen Zhen、Yamasaki Tomoteru、Chen Jiahui、Xiao Zhiwei、Ishii Hideki、Hiraishi Atsuto、Shao Tuo、Zhang Yiding、Hu Kuan、Xie Lin、Fujinaga Masayuki、Zhao Chunyu、Mori Wakana、Collier Thomas、Haider Ahmed、Tomita Susumu、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 65 Issue: 13 Pages: 9144-9158
- DOI
  10.1021/acs.jmedchem.2c00377
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Assessment of cholesterol homeostasis in the living human brain2022
- Author(s)
  Haider Ahmed、Zhao Chunyu、Wang Lu、Zhang Ming-Rong、Liang Steven et al
- Journal Title
  
  Science Translational Medicine
  
  Volume: 14 Issue: 665
- DOI
  10.1126/scitranslmed.adc9967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Peptide-based nanomaterials: Self-assembly, properties and applications2022
- Author(s)
  Li Tong、Lu Xian-Mao、Zhang Ming-Rong、Hu Kuan、Li Zhou
- Journal Title
  
  Bioactive Materials
  
  Volume: 11 Pages: 268-282
- DOI
  10.1016/j.bioactmat.2021.09.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873
[Journal Article] Flexible Supercapacitors Based on Graphene/Boron Nitride Nanosheets Electrodes and PVA/PEI Gel Electrolytes2021
- Author(s)
  Wang Chan、Hu Kuan、Liu Ying、Zhang Ming-Rong、Wang Zhiwei、Li Zhou
- Journal Title
  
  Materials
  
  Volume: 14 Issue: 8 Pages: 1955-1955
- DOI
  10.3390/ma14081955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Novel Reversible-Binding PET Ligands for Imaging Monoacylglycerol Lipase Based on the Piperazinyl Azetidine Scaffold2021
- Author(s)
  Rong Jian, Mori Wakana, Xia Xiaotian, Zhang Ming-Rong, Liang Steven
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 19 Pages: 14283-14298
- DOI
  10.1021/acs.jmedchem.1c00747
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
[Journal Article] Neuroprotective effects of minocycline and KML29, a potent inhibitor of monoacylglycerol lipase, in an experimental stroke model: a small-animal positron emission tomography study2021
- Author(s)
  Yamasaki Tomoteru, Hatori Akiko, Zhang Yiding, Kurihara Yusuke, Ogawa Masanao, Wakizaka Hidekatsu, Rong Jian, Wang Lu, Huan Liang, Zhang Ming-Rong
- Journal Title
  
  Theranostics
  
  Volume: 11 Issue: 19 Pages: 9492-9502
- DOI
  10.7150/thno.64320
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Imaging the trace amine-associated receptor 1 by positron emission tomography2021
- Author(s)
  Sun Jiyun, Chen Jiahui, Kumata Katsushi, Xiao Zhiwei, Rong Jiang, Haider Ahmed, Shao Tuo, Wang Lu, Xu Hao, Zhang Ming-Rong, Liang Steven
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 70 Pages: 153007-153007
- DOI
  10.1016/j.tetlet.2021.153007
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Development of a Stable Peptide-Based PET Tracer for Detecting CD133-Expressing Cancer Cells2021
- Author(s)
  Hu Kuan、Ma Xiaohui、Xie Lin、Zhang Yiding、Hanyu Masayuki、Obata Honoka、Zhang Lulu、Nagatsu Kotaro、Suzuki Hisashi、Shi Rui、Wang Weizhi、Zhang Ming-Rong
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 1 Pages: 334-341
- DOI
  10.1021/acsomega.1c04711
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659, KAKENHI-PROJECT-21K07714
[Journal Article] Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping2021
- Author(s)
  Chen Zhen, Wakana Mori, Rong Jian, Schafroth Michael A, Ogasawara Daisuke, Yamasaki Tomoteru, Hiraishi Atsuto, Hatori Akiko, Zhang Yiding, Hu Kuan, Fujinaga Masayuki, Cravatt Benjamin F., Josephson Lee, Zhang Ming-Rong, Liang Steven
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: 11 Pages: 1686-1695
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Journal Article] Recent developments on PET radiotracers for TSPO and their applications in neuroimaging2021
- Author(s)
  Zhang Lingling、Hu Kuan、Shao Tuo、Hou Lu、Zhang Shaojuan、Ye Weijian、Josephson Lee、Meyer Jeffrey H.、Zhang Ming-Rong、Vasdev Neil、Wang Jinghao、Xu Hao、Wang Lu、Liang Steven H.
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: 11 Issue: 2 Pages: 373-393
- DOI
  10.1016/j.apsb.2020.08.006
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping2021
- Author(s)
  Chen Zhen、Mori Wakana、Rong Jian、Schafroth Michael A.、Shao Tuo、Van Richard S.、Ogasawara Daisuke、Yamasaki Tomoteru、Hiraishi Atsuto、Hatori Akiko、Chen Jiahui、Zhang Yiding、Hu Kuan、Fujinaga Masayuki、Sun Jiyun、Yu Qingzhen、Collier Thomas L.、et al.
- Journal Title
  
  Acta Pharmaceutica Sinica B
  
  Volume: In press Issue: 6 Pages: 1686-1695
- DOI
  10.1016/j.apsb.2021.01.021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-21H02873
[Journal Article] Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy2021
- Author(s)
  Xie Lin, Hu Kuan, Duo Yanhong, Shimokawa Takashi, Kumata Katsushi, Zhang Yiding, Jiang Cuiping, Zhang Lulu, Nengaki Nobuki, Wakizaka Hidekatsu, Cao Yihai, Zhang Ming-Rong
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 9 Issue: 6 Pages: e002616-e002616
- DOI
  10.1136/jitc-2021-002616
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-21K07659
[Journal Article] <sup>211</sup>At-Labeled Polymer Nanoparticles for Targeted Radionuclide Therapy of Glucose-Dependent Insulinotropic Polypeptide Receptor (GIPR)-Overexpressed Cancer2021
- Author(s)
  Shi Xiumin、Li Qing、Zhang Lulu、Hanyu Masayuki、Xie Lin、Hu Kuan、Nagatsu Kotaro、Zhang Chuan、Wu Zhengcan、Wang Feng、Zhang Ming-Rong、Yang Kai、Zhu Ran
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 32 Issue: 8 Pages: 1763-1772
- DOI
  10.1021/acs.bioconjchem.1c00263
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-21H02873, KAKENHI-PROJECT-21K07659
[Journal Article] Customization of Conductive Elastomer Based on PVA/PEI for Stretchable Sensors2020
- Author(s)
  Wang Chan、Hu Kuan、Zhao Chaochao、Zou Yang、Liu Ying、Qu Xuecheng、Jiang Dongjie、Li Zhe、Zhang Ming‐Rong、Li Zhou
- Journal Title
  
  Small
  
  Volume: 16 Issue: 7 Pages: 1904758-1904758
- DOI
  10.1002/smll.201904758
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] PET Imaging of VEGFR with a Novel 64Cu-Labeled Peptide2020
- Author(s)
  Hu Kuan、Shang Jingjie、Xie Lin、Hanyu Masayuki、Zhang Yiding、Yang Zhimin、Xu Hao、Wang Lu、Zhang Ming-Rong
- Journal Title
  
  ACS Omega
  
  Volume: 5 Issue: 15 Pages: 8508-8514
- DOI
  10.1021/acsomega.9b03953
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and preliminary evaluation of 18F-labeled 1-(6,7-dimethyl-4-(methylamino)-1,3-dihydro-2H-pyrrolo[3,4-c]pyridin-2-yl)-2-(trans-2-(6-fluoropyridin-3-yl)cyclopropyl)ethan-1-one for imaging muscarinic acetylcholine receptor subtype 42020
- Author(s)
  Deng Xiaoyun、Zhang Yiding、Rong Jian、Kumata Katsushi、Shao Tuo、Wang Gangqiang、Hatori Akiko、Mori Wakana、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Shao Yihan、Josephson Lee、Sun Shaofa、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 61 Issue: 27 Pages: 152060-152060
- DOI
  10.1016/j.tetlet.2020.152060
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and evaluation of 6-(11C-methyl(4-(pyridin-2-yl)thiazol-2-yl)amino)benzo[d]thiazol-2(3H)-one for imaging γ-8 dependent transmembrane AMPA receptor regulatory protein by PET2020
- Author(s)
  Yu Qingzhen、Kumata Katsushi、Li Hua、Zhang Yiding、Chen Zhen、Zhang Xiaofei、Shao Tuo、Hatori Akiko、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Wang Gangqiang、Josephson Lee、Sun Shaofa、Zhang Ming-Rong、Liang Steven H.
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 4 Pages: 126879-126879
- DOI
  10.1016/j.bmcl.2019.126879
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16495, KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Identification and Development of a New Positron Emission Tomography Ligand 4-(2-Fluoro-4-[11C]methoxyphenyl)-5-((1-methyl-1H-pyrazol-3-yl)methoxy)picolinamide for Imaging Metabotropic Glutamate Receptor Subtype 2 (mGlu2)2020
- Author(s)
  Yamasaki Tomoteru、Zhang Xiaofei、Kumata Katsushi、Zhang Yiding、Deng Xiaoyun、Fujinaga Masayuki、Chen Zhen、Mori Wakana、Hu Kuan、Wakizaka Hidekatsu、Hatori Akiko、Xie Lin、Ogawa Masanao、Nengaki Nobuki、Van Richard、Shao Yihan、Sheffler Douglas J.、Cosford Nicholas D. P.、Liang Steven H.、Zhang Ming-Rong
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 63 Issue: 20 Pages: 11469-11483
- DOI
  10.1021/acs.jmedchem.9b01991
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Boron agents for neutron capture therapy2020
- Author(s)
  Hu Kuan、Yang Zhimin、Zhang Lingling、Xie Lin、Wang Lu、Xu Hao、Josephson Lee、Liang Steven H.、Zhang Ming-Rong
- Journal Title
  
  Coordination Chemistry Reviews
  
  Volume: 405 Pages: 213139-213139
- DOI
  10.1016/j.ccr.2019.213139
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and preliminary evaluation of novel 11C-labeled GluN2B-selective NMDA receptor negative allosteric modulators2020
- Author(s)
  Sun Ji-yun、Kumata Katsushi、Chen Zhen、Zhang Yi-ding、Chen Jia-hui、Hatori Akiko、Fu Hua-long、Rong Jian、Deng Xiao-yun、Yamasaki Tomoteru、Xie Lin、Hu Kuan、Fujinaga Masayuki、Yu Qing-zhen、Shao Tuo、Collier Thomas Lee、Josephson Lee、Shao Yi-han、Du Yun-fei、Wang Lu、Xu Hao、Zhang Ming-rong、Liang Steven H
- Journal Title
  
  Acta Pharmacologica Sinica
  
  Volume: 42 Issue: 3 Pages: 491-498
- DOI
  10.1038/s41401-020-0456-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Self-Assembly of Constrained Cyclic Peptides Controlled by Ring Size2020
- Author(s)
  Hu Kuan、Xiong Wei、Sun Chengjie、Wang Chan、Li Jingxu、Yin Feng、Jiang Yixiang、Zhang Ming-Rong、Li Zhou、Wang Xinwei、Li Zigang
- Journal Title
  
  CCS Chemistry
  
  Volume: 2 Issue: 1 Pages: 42-51
- DOI
  10.31635/ccschem.020.201900047
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and preliminary evaluation of 4-hydroxy-6-(3-[11C]methoxyphenethyl)pyridazin-3(2H)-one, a 11C-labeled -amino acid oxidase (DAAO) inhibitor for PET imaging2020
- Author(s)
  Deng Xiaoyun、Zhang Yiding、Chen Zhen、Kumata Katsushi、Van Richard、Rong Jian、Shao Tuo、Hatori Akiko、Mori Wakana、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Wey Hsiao-Ying、Shao Yihan、Josephson Lee、Murtas Giulia、Pollegioni Loredano、Zhang Ming-Rong、Liang Steven
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 16 Pages: 127326-127326
- DOI
  10.1016/j.bmcl.2020.127326
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Smart Titanium Coating Composed of Antibiotic Conjugated Peptides as an Infection‐Responsive Antibacterial Agent2020
- Author(s)
  Zhang Yunfei、Hu Kuan、Xing Xuan、Zhang Jingshuang、Zhang Ming‐Rong、Ma Xiaohui、Shi Rui、Zhang Liqun
- Journal Title
  
  Macromolecular Bioscience
  
  Volume: 21 Issue: 1 Pages: 2000194-2000194
- DOI
  10.1002/mabi.202000194
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Synthesis and preliminary studies of 11C-labeled tetrahydro-1,7-naphthyridine-2-carboxamides for PET imaging of metabotropic glutamate receptor 22020
- Author(s)
  Zhang Xiaofei、Zhang Yiding、Chen Zhen、Shao Tuo、Van Richard、Kumata Katsushi、Deng Xiaoyun、Fu Hualong、Yamasaki Tomoteru、Rong Jian、Hu Kuan、Hatori Akiko、Xie Lin、Yu Qingzhen、Ye Weijian、Xu Hao、Sheffler Douglas J.、Cosford Nicholas D. P.、Shao Yihan、Tang Pingping、Wang Lu、Zhang Ming-Rong、Liang Steven H.
- Journal Title
  
  Theranostics
  
  Volume: 10 Issue: 24 Pages: 11178-11196
- DOI
  10.7150/thno.42587
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] 3-(Cyclopropylmethyl)-7-((4-(4-[11C]methoxyphenyl)piperidin-1-yl)methyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine: Synthesis and preliminary evaluation for PET imaging of metabotropic glutamate receptor subtype 22020
- Author(s)
  Kumata Katsushi、Zhang Yiding、Ogawa Masanao、Kurihara Yusuke、Mori Wakana、Hu Kuan、Fujinaga Masayuki、Nengaki Nobuki、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 23 Pages: 127555-127555
- DOI
  10.1016/j.bmcl.2020.127555
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635, KAKENHI-PROJECT-19K17156
[Journal Article] Harnessing the PD-L1 interface peptide for positron emission tomography imaging of the PD-1 immune checkpoint2020
- Author(s)
  Hu Kuan、Xie Lin、Hanyu Masayuki、Zhang Yiding、Li Lingyun、Ma Xiaohui、Nagatsu Kotaro、Suzuki Hisashi、Wang Weizhi、Zhang Ming-Rong
- Journal Title
  
  RSC Chemical Biology
  
  Volume: 1 Issue: 4 Pages: 214-224
- DOI
  10.1039/d0cb00070a
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
[Journal Article] Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy2020
- Author(s)
  Hu Kuan、Xie Lin、Zhang Yiding、Hanyu Masayuki、Yang Zhimin、Nagatsu Kotaro、Suzuki Hisashi、Ouyang Jiang、Ji Xiaoyuan、Wei Junjie、Xu Hao、Farokhzad Omid C.、Liang Steven H.、Wang Lu、Tao Wei、Zhang Ming-Rong
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 2778-2778
- DOI
  10.1038/s41467-020-16513-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156
[Journal Article] Radiotheranostic Agent 64Cu-cyclam-RAFT-c(-RGDfK-)4 for Management of Peritoneal Metastasis in Ovarian Cancer2020
- Author(s)
  Jin Zhao-Hui、Tsuji Atsushi B.、Degardin Melissa、Sugyo Aya、Obara Satoshi、Wakizaka Hidekatsu、Nagatsu Kotaro、Hu Kuan、Zhang Ming-Rong、Dumy Pascal、Boturyn Didier、Higashi Tatsuya
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 26 Issue: 23 Pages: 6230-6241
- DOI
  10.1158/1078-0432.ccr-20-1205
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07776, KAKENHI-PROJECT-18H02774, KAKENHI-PROJECT-19K17156
[Journal Article] A Hybrid Biofuel and Triboelectric Nanogenerator for Bioenergy Harvesting2020
- Author(s)
  Li Hu、Zhang Xiao、Zhao Luming、Jiang Dongjie、Xu Lingling、Liu Zhuo、Wu Yuxiang、Hu Kuan、Zhang Ming-Rong、Wang Jiangxue、Fan Yubo、Li Zhou
- Journal Title
  
  Nano-Micro Letters
  
  Volume: 12 Issue: 1 Pages: 50-50
- DOI
  10.1007/s40820-020-0376-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Journal Article] Developing native peptide-based radiotracers for PD-L1 PET imaging and improving imaging contrast by pegylation2019
- Author(s)
  Kuan Hu、Masayuki Hanyu、Xie Lin、Zhang Yiding、Kotaro Nagatsu、Hisashi Suzuki、Zhang Ming-Rong
- Journal Title
  
  Chemical Communications
  
  Volume: 55 Issue: 29 Pages: 4162-4165
- DOI
  10.1039/c9cc00445a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-17K16495
[Journal Article] 131I-IITM and 211At-AITM: Two Novel Small-Molecule Radiopharmaceuticals Targeting Oncoprotein Metabotropic Glutamate Receptor 12019
- Author(s)
  Xie Lin、Hanyu Masayuki、Fujinaga Masayuki、Zhang Yiding、Hu Kuan、Minegishi Katsuyuki、Jiang Cuiping、Kurosawa Fuki、Morokoshi Yukie、Li Huizi Keiko、Hasegawa Sumitaka、Nagatsu Kotaro、Zhang Ming-Rong
- Journal Title
  
  Journal of Nuclear Medicine
  
  Volume: 61 Issue: 2 Pages: 242-248
- DOI
  10.2967/jnumed.119.230946
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07281, KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
[Journal Article] Radiosynthesis and evaluation of a novel monoacylglycerol lipase radiotracer: 1,1,1,3,3,3-hexafluoropropan-2-yl-3-(1-benzyl-1H-pyrazol-3-yl)azetidine-1-[11C]carboxylate2019
- Author(s)
  Mori Wakana、Hatori Akiko、Zhang Yiding、Kurihara Yusuke、Yamasaki Tomoteru、Xie Lin、Kumata Katsushi、Hu Kuan、Fujinaga Masayuki、Zhang Ming-Rong
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 27 Issue: 16 Pages: 3568-3573
- DOI
  10.1016/j.bmc.2019.06.037
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-17K16495
[Journal Article] Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a “Tail Switching” Strategy on a Piperazinyl Azetidine Skeleton2019
- Author(s)
  Chen Zhen、Mori Wakana、Deng Xiaoyun、Cheng Ran、Ogasawara Daisuke、Zhang Genwei、Schafroth Michael A.、Dahl Kenneth、Fu Hualong、Hatori Akiko、Shao Tuo、Zhang Yiding、Yamasaki Tomoteru、Zhang Xiaofei、Rong Jian、Yu Qingzhen、Hu Kuan、Fujinaga Masayuki、Xie Lin、Kumata Katsushi、Gou Yuancheng、Chen Jingjin、Gu Shuyin
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 62 Issue: 7 Pages: 3336-3353
- DOI
  10.1021/acs.jmedchem.8b01778
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10461, KAKENHI-PROJECT-18H06217, KAKENHI-PROJECT-17H04267, KAKENHI-PROJECT-17K16495
[Journal Article] Synthesis and Preliminary Evaluation of 11C‐Labeled VU0467485/AZ13713945 and Its Analogues for Imaging Muscarinic Acetylcholine Receptor Subtype2019
- Author(s)
  Xiaoyun Deng Akiko Hatori Zhen Chen Katsushi Kumata Tuo Shao Xiaofei Zhang Tomoteru Yamasaki Kuan Hu Qingzhen Yu Longle Ma Gangqiang Wang Lu Wang Yihan Shao Lee Josephson Shaofa Sun Ming‐Rong Zhang Steven Liang
- Journal Title
  
  ChemMedChem
  
  Volume: 14 Issue: 3 Pages: 303-309
- DOI
  10.1002/cmdc.201800710
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06217
[Presentation] TRT薬剤211At-AITM誘導体の合成と評価2022
- Author(s)
  破入　正行, 謝　琳, 張　一鼎, 峯岸　克行, 門間　あゆみ, Hu　Kuan, 藤永　雅之, 永津　弘太郎, 石岡　典子, 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Development of metabotropic glutamate receptor 1-targeted radiopharmaceuticals for theranostics of melanoma2022
- Author(s)
  Xie Lin, Hanyu Masayuki, Fujinaga Masayuki, Lulu Zhang, Yiding Zhang, Mori Wakana, Hu Kuan, Minegishi Katsuyuki, Nagatsu Kotaro, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Synthesis and evaluation of At-211 labeled TRT-radiopharmaceuticals (At-AITM) for melanoma with overexpressed metabotropic glutamate receptor 1.2022
- Author(s)
  Hanyu Masayuki, Xie Lin, Yiding Zhang, Minegishi Katsuyuki, Kadoma Ayumi, Hu Kuan, Fujinaga Masayuki, Nagatsu Kotaro, Ishioka Noriko, Zhang Ming-Rong
- Organizer
  13th congress of the World Federation of Nuclear Medicine and Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] 癌蛋白質mGluR1に基づくラジオセラノスティクス薬剤の開発2022
- Author(s)
  謝　琳, 破入　正行, 藤永　雅之, 張　一鼎, 張露露, 森　若菜, Hu　Kuan, 峯岸　克行, 永津　弘太郎, 張　明栄
- Organizer
  第62回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Theranostics of melanoma targeting metabotropic glutamate receptor 1 with a novel small-molecular radiopharmaceutical pair2022
- Author(s)
  Xie Lin, Hanyu Masayuki, Fujinaga Masayuki, Lulu Zhang, Yiding Zhang, Mori Wakana, Hu Kuan, Minegishi Katsuyuki, Nagatsu Kotaro, Kawamura Kazunori, Zhang Ming-Rong
- Organizer
  SNMMI2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] PEGylation modulation of peptides promotes PET detection of cancers2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
- Organizer
  eSRS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] 11C-L-1MTrp-PETによるメラノーマ免疫化学療法における免疫応答判定2021
- Author(s)
  謝　琳, Hu　Kuan, 熊田　勝志, 脇坂　秀克, 張　一鼎, 念垣　信樹, 下川　卓志, 張　明栄
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021
- Author(s)
  Hu Kuan, Xie Lin, Zhang Yiding, Hanyu Masayuki, Zhang Ming-Rong
- Organizer
  第61回日本核医学会学術総会, 日本核医学会
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] Development of a stable peptide-based PET tracer for detecting CD133-expressing cancer stem cells2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Obata Honoka , Nagatsu Kotaro , Suzuki Hisashi , Zhang Ming-Rong
- Organizer
  第4回日本核医学会分科会放射線薬品科学研究会第20回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] RADIOLABELLING AND PET IMAGING OF COPPER-64 LABELED ISODGR DERIVATIVE2021
- Author(s)
  Masayuki Hanyu , Lin Xie , Hu Kuan , Yiding Zhang , Ming-Rong Zhang
- Organizer
  第57回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021
- Author(s)
  Hu　Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong:
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] TRT薬剤「211At-AITM」合成法の改良2021
- Author(s)
  破入　正行, 峯岸　克行, 門間　あゆみ, 謝　琳, Hu　Kuan, 張　一鼎, 藤永　雅之, 永津　弘太郎, 張　明栄
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Whole-body PET Tracking of a D-dodecapeptide and its Radiotheranostic Potential for PD-L1 overexpressed tumors2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
- Organizer
  SNMMI2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Whole-body PET Tracking of a D-dodecapeptide and its Radiotheranostic Potential for PD-L1 overexpressed tumors2021
- Author(s)
  Hu Kuan, Xie Lin, Zhang Yiding, Hanyu Masayuki, Zhang Ming-Rong
- Organizer
  SNMMI2021, Society of Nuclear Medicine and Molecular Imaging
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] PEGylation modulation of peptides promotes PET detection of cancers2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
- Organizer
  eSRS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] Imaging urokinase plasminogen activator with a cyclic peptide-based PET tracer2021
- Author(s)
  Hu　Kuan, Xie Lin, Yiding Zhang, Hanyu Masayuki, Zhang Ming-Rong
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Stapled Peptide-based radiotheranostics agent targeting MDM2 suppresses p53-mutant tumor growth2021
- Author(s)
  Hu Kuan , Xie Lin , Yiding Zhang , Hanyu Masayuki , Zhang Ming-Rong
- Organizer
  SNMMI2021 ANNUAL MEETING
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021
- Author(s)
  Hu Kuan, Xie Lin, Hanyu Masayuki, Zhang Yiding, Zhang Ming-Rong
- Organizer
  eSRS, Society of Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] Synthesis, Radiolabeling and Biological Evaluation of a Novel Trace Amine-Associated Receptor 1 (TAAR1) PET radioligand2021
- Author(s)
  Haider Ahmed, Sun Jiyun, Chen Jiahui, Rong Jian, Shao Tuo, Wang Lu, Xu Hao, Zhang Ming-Rong, Liang Steven
- Organizer
  eSRS, Society of Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] In vivo PET imaging of cancer α5β1-integrin using a pegylated peptide2021
- Author(s)
  Hu　Kuan , 謝　琳 , 張　一鼎 , 破入　正行 , 張　明栄:
- Organizer
  第61回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021
- Author(s)
  Hu Kuan , Xie Lin , Hanyu Masayuki , Yiding Zhang , Zhang Ming-Rong
- Organizer
  eSRS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Stapled Peptide-based radiotheranostics agent targeting MDM2 suppresses p53-mutant tumor growth2021
- Author(s)
  Hu Kuan
- Organizer
  SNMMI2021 ANNUAL MEETING
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02873
[Presentation] PET imaging of PD-L1 overexpressing tumors with a 68Ga labeled D-dodecapeptide2021
- Author(s)
  Hu Kuan, Xie Lin, Hanyu Masayuki, Yiding Zhang, Zhang Ming-Rong
- Organizer
  eSRS, Society of Radiopharmaceutical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07659
[Presentation] Harnessing PD-L1 interface peptide for PET imaging of PD-1 immune checkpoint2020
- Author(s)
  Hu Kuan , Lin Xie , Yiding Zhang , Masayuki Hanyu , Ming-Rong Zhang
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Development of novel 18F-labeled PET tracers for imaging TSPO with insensitivity to rs6971 polymorphism2020
- Author(s)
  Lingling Zhang , Masayuki Fujinaga , Bin Ji , Hu Kuan , Weijian Ye , Lin Xie , Yiding Zhang , Lu Hou , Hao Xu , Ming-Rong Zhang , Wang Lu
- Organizer
  SNMMI 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] PET Imaging of VEGFR with a Novel <SUP>64</SUP>Cu Labeled Peptide2020
- Author(s)
  Hu Kuan , Lin Xie , Yiding Zhang , Masayuki Hanyu , Ming-Rong Zhang
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Positron Emission Tomography Imaging of Vascular Endothelial Growth Factor Receptor Expression with a new 64Cu labeled peptide2020
- Author(s)
  Hu, Kuan Shang, Jingjie Xie, Lin Hanyu, Masayuki Zhang, Yiding Yang, Zhimin Yang, Zhimin Xu, Hao Wang, Lu Zhang, Ming-Rong
- Organizer
  SNMMI 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Synthesis and preclinical evaluation of 11C-labeled (6-aryl-1H-pyrrolo[3,2-b]pyridin-1-yl)acetamide for imaging GluN2B subunit of NMDA receptors2020
- Author(s)
  Jiyun Sun, Zhen Chen, Jiahui Chen, Hualong Fu, Tuo Shao, Wang Lu, Hao Xu, Ming-Rong Zhang, Steven H. Liang
- Organizer
  SNMMI 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03635
[Presentation] 癌蛋白質mGluR1に基づくがん種横断的な211At-AITM標的アイソトープ治療法の開発2020
- Author(s)
  謝　琳 , 張　露露 , 破入　正行 , 藤永　雅之 , 張　一鼎 , 峯岸　克行 , Hu　Kuan , 李　惠子 , 長谷川　純崇 , 永津　弘太郎 , 張　明栄
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Dual targeting of PD-L1 and integrin for preclinical PET imaging of cancers2019
- Author(s)
  Hu　Kuan
- Organizer
  第59回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Develop a peptide-based PET radiotracer for imaging PD-L1 expression in cancer2019
- Author(s)
  Hu　Kuan, Lin Xie, Masayuki Hanyu, Yiding Zhang, Ming-Rong Zhang
- Organizer
  ISRS2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] PET imaging of VEGFR-2 with a novel 64Cu labeled peptide2019
- Author(s)
  Hu　Kuan, Ming-Rong Zhang
- Organizer
  第19回放射性医薬品・画像診断薬研究会での口頭発表
- Data Source
  KAKENHI-PROJECT-19K17156
[Presentation] Develop a peptide-based PET radiotracer for imaging PD-L1 expression in cancer2018
- Author(s)
  胡寛
- Organizer
  The 10th China-Japan-Korea Symposium on Radiopharmaceutical Sciences(CJKSRS 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06217
[Presentation] Radiolabeled Peptide for Anti-PD-L1 Imaging and Therapy2018
- Author(s)
  Hu　Kuan , 謝　琳 , 破入　正行 , 張　明栄
- Organizer
  第2回日本核医学会分科会放射性薬品科学研究会第18回放射性医薬品・画像診断薬研究会
- Data Source
  KAKENHI-PROJECT-18H06217

1. Zhang Ming-Rong (80443076)

# of Collaborated Projects: 3 results

# of Collaborated Products: 42 results
2. Xie Lin (30623558)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
3. 藤永雅之 (70623726)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. 破入正行 (80435552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. 河村和紀 (50401766)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山崎友照 (80627563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 羽鳥晶子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 金朝暉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hu Kuan 胡 寛

Research Projects

Research Products

Co-Researchers

Stapled peptide-based radiotheranostics for intracellular protein-protein interactions targeted cancer imaging and therapyPrincipal Investigator

Principal Investigator

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Research Institution

Construction of a mGluR1-targeted radiotheranostic system for tumor-agnostic cancer treatment

Principal Investigator

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Review Section

Research Institution

Development of PET probes for gama 8-dependent transmembrane AMPA receptor regulatory protein

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chemoselective methionine 18F-fluorination on unprotected peptides for positron-emission tomography imagingPrincipal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Stabilized peptide targeting programmed death-ligand 1 for Positron Emission Tomography imaging and cancer immunotherapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Preclinical Evaluation of Novel Positron Emission Tomography (PET) Probes for Imaging Leucine-Rich Repeat Kinase 2 (LRRK2)2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a 68Gallium-Labeled D-Peptide PET Tracer for Imaging Programmed Death-Ligand 1 Expression2023

Author(s)

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Data Source

[Journal Article] A 211At-labelled mGluR1 inhibitor induces cancer senescence to elicit long-lasting anti-tumor efficacy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Novel 11C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Linear Peptide-Based PET Tracers for Imaging PD-L1 in Tumors2023

Author(s)

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DOI

Data Source

[Journal Article] Small-animal PET study for noninvasive quantification of transmembrane AMPA receptor regulatory protein γ8 (TARP γ-8) in the brain2023

Author(s)

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DOI

Data Source

[Journal Article] A multifunctional nanotheranostic agent potentiates erlotinib to EGFR wild-type non-small cell lung cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PEIGel: A biocompatible and injectable scaffold with innate immune adjuvanticity for synergized local immunotherapy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Imaging of Transmembrane AMPA Receptor Regulatory Proteins by Positron Emission Tomography2022

Hu Kuan 胡寛