KIRINO YUTAKA 桐野豊

… Alternative Names

KIRINO Yutaka 桐野豊

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Researcher Number	10012668
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Affiliation (Current)	2022: 徳島文理大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019: 徳島文理大学, 薬学部, 教授 2017 – 2018: 徳島文理大学, 薬学部, 名誉教授 2012 – 2016: 徳島文理大学, 薬学部, 教授 2006 – 2008: 徳島文理大学, 香川薬学部, 教授 2005: 東京大学, 大学院・薬学系研究所, 教授 … More 1997 – 2005: 東京大学, 大学院・薬学系研究科, 教授 1997 – 1998: 東京大学, 大学院・薬学研究科, 教授 1996: Professor, School of Pharmaceutical Sciences, The University of Tokyo, 大学院・薬学系研究所, 教授 1993 – 1996: The University of Tokyo, Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 1992: 九州大, 薬学部, 教授 1986 – 1992: 九州大学, 薬学部, 教授 1986: 九大, 薬学部, 教授 1985: 東京大学, 薬, 助教授 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Physical pharmacy / Biological Sciences / 分子遺伝学・分子生理学 / Biophysics / 生物物性学 / 医薬分子機能学 Except Principal Investigator Biophysics / Neuroscience in general / 生物物性学 … More / Physical pharmacy / Physical pharmacy / Chemical pharmacy / Medical pharmacy / Biological Sciences / 分子遺伝学・分子生理学 Less
Keywords	Principal Investigator ナメクジ / 連合学習 / カルシウムチャネル / differential display / 再構成膜 / シナプトソーム / 膜電位感受性色素 / イメージング / LAPS18 / differential display法 … More / 神経科学 / 脳・神経 / 瞬目反射条件付け / イオンチャネル / 巨大化ベシクル / アセチルコリン / シビレエイ / 電気器官 / 前脳 / 細胞膜 / 核 / 電気生理学 / 細胞内情報伝達 / 蛋白質リン酸化 / 嗅覚-味覚連合学習 / 表面電荷 / 学習 / 単離脳 / 初代培養神経細胞 / タンパク合成 / 長期記憶 / 脳神経節 / 軟体動物 / 生物物理化学 / 学習・記憶 / 巨大ベシクル / 筋小胞体 / ESR / シビレエイ電気器官 / シナプス前神経終末 / リン脂質非対称分布 / Electric organ / Acetylcholine / Calcium channel / Electric Ray / associative learning / slug / procerebrum / 神経筋接合部 / 自己免疫疾患 / Synaptosome / 遺伝子発現 / インフォメ-ションフロ- / 光学顕微鏡技術 / イメ-ジング生理学 / インフォメーションフロー / イメージング生理学 / 膜電位感受性蛍光色素 / 異質平面膜 / 冷却CCDカメラ / 高速差分増幅式カメラ / ナメクジ中枢神経 / 水平平面膜 / シングルホトダイオードカメラ / ナメクジ神経細胞 / 瞬目反射 / 古典的条件付け / モルモット / 小脳 / 海馬 / 除脳 / 脳研究 / 生物物理学的アプローチ / 細胞シグナリング / 時空間パターン / 免疫組織化学 / 成長円錐 / 神経回路 / 光学測定 / 嗅覚中枢 / di-4-ANEPPS / クマリン / アンチセンストランスクリプト / アルコールデヒドロゲナーゼ / 一酸化窒素合成酵素 / 発現誘導 / 内在性アンチセンス / 遺伝子発現調節 / 行動学 / 瞬目反射条件づけ / サル / PET / カルシウム / イオン輸送 / パッチクランプ法 / 凍結-融解法 / カルシウム・ポンプ / 平面膜 / カルシウムポンプ / 平面膜法 / 再構成 / 心筋細胞膜 / 心筋細胞膜ベシクル / 脂質平面膜 / 単一チャネル電流 / 細胞質因子 / B型Ca^<2+>チャネル / 脂質平面膜法 / L型Caチャネル / ジヒドロピリジン化合物 / 活性酸素 / Ca取り込み / ion channels / reconstitution / planar bilayer / cardiac sarcolemmal membranes / 酸素濃度 / ニトロキシド / LバンドESR / 常磁性プローブ / 生体内酸素 / ニトロキシドラジカル / 活性炭 / 常磁性 / L-バンドESR / 電子スピン共鳴法 / 生体内酸素濃度測定法 / 細胞内酸素濃度 / 無侵襲測定 / 酸素傷害 / Oxygen concentration / Nitroxide / L-band ESR / Paramagnetic probe / エクソサイトーシス / 肥満細胞 / 脱顆粒 / 神経シナプス / Caチャネル / 神経伝達物質の遊離 / Presynaptic terminal / Exocytosis / Mast cells / Degranulation / Asymmetric distribution of phospholipids / cDNAライブラリー / シナプトソーム内カルシウム / 抗体カラムクロマトグラフィー / electric organ / synaptosome / calcium channel / acetylcholine / cDNA library / intra-synaptosomal calcium / アデノシン受容体 / ランバート・イ-トン症候群 / 神経前終末 / アセチルコリン遊離 / アデノシン / Presynaptic terminals / Adenosine receptors / Ca channels / Lambert-Eaton syndrome / 嗅覚 / 細胞外マトリックス蛋白 / コウラナメクジ / cDNA / 5'-RACE法 / olfaction / extracellular matrix protein / モノクローナル抗体 / ランバート・イートン症候群 / Neuromuscular Junction / Autoimmune Disease / Electric Organ / Monoclonal Antibody / CaィイD12+ィエD1 Channel / 非バースト神経 / 抑制性シナプス後電位 / in vitro学習 / バースト放電 / ナイスタチン穿孔パッチ法 / 遺伝子導入 / RNAi / 神経修飾物質 / nonbursting neuron / inhibitory postsynaptic potential / in vitro learning / burst dischanges / nystatin perforated patch recording / ランバート・イートン筋無力症 / マウス / ダウンレギュレーション / internalization / モデル動物 / Autoimmune disease / Lambert-Eaton myasthenic syndrome / 嗅覚忌避学習 / 前脳葉 / 活動マーカー遺伝子 / 条件刺激 / 無条件刺激 / シナプス可塑性 / 神経可塑性 / シナプス電位 / 嗅覚学習 / Land slug / Olfactory aversive learning / Procerebral lobe / Differential display / Activity marker gene / Conditioned stimulus / Unconditioned stimulus / Synaptic plasticity / シナプス小胞 / シナプス前膜 / 神経伝達物質放出機構 / Synaptic Vesicle / Presynaptic membrane / Giant vesicle / Ton channel / 電気穿孔法 / 電気的細胞融合法 / パルスレ-ザ-顕微鏡 / 遺伝子移入 / 膜の再構成 / リン脂質平面膜 / リポソ-ム / 起電性イオンポンプ / 電場融合法 / 生体膜 / 膜電位 / Electroporation / Electrofusion / Pulse laser microscope / Gene transfer / Membrane reconstitution / Surface charge / タウタンパク質 / 神経原線維変化 / 学習と記憶 / 遺伝子変異マウス / アルツハイマー病モデル / モリス水迷路試験 / 新奇物体探索試験 / アルツハイマー病 / 認知障害 / 行動神経科学 / マウスモデル … More Except Principal Investigator 膜融合 / 連合学習 / 海馬 / イメージング / イオンチャネル / シナプス / Kチャネル / シナプス小胞 / 記憶・学習 / 記憶 / 走査プローブ顕微鏡 / 顕微光学技術 / 生物物理学 / 脳研究 / 共焦点レーザ顕微鏡 / 小脳 / Ion Channel / インパルス伝達 / 伝達物質の放出 / 蛍光顕微測光システム / 神経伝達 / 共同研究の推進 / 研究情報の流通 / サ-キュラ-の発行 / 細胞内カルシウム / Kチャンネルの修飾機構 / PS結合タンパク質 / プレシナプスモデル / 低分子量Gタンパク / 長期増強 / Ca_<2+>チャネル / 可塑性 / 伝達物質放出 / シナプシン / トランスミッター / シナプス小脳 / Caチヤネル / プレシナプス / タンパク質リン酸化 / レキナーゼ / 脱リン酸化 / リサイクリング / アクチブゾーン / カルシウムチャンネル / 神経インパルス / 脳機能 / シナプス伝達 / ウミウシ / パヅチクランプ / 脳虚血 / カルシウム / スナネズミ / Neurobiology / Neural System / Physiology / Computational Newroscieuce / Developmental Newrobiologg / Marine Biological Laboratory / Fear Conditioning / Synaptic vesicle / SNARE / Synaptic plasticity / Associative learning / membrane fusion / CaMK / PKA / Fear conditioning / Synerphin / Synapsin I / Free energy barrier / Map Kinase / SNARE複合体 / リン酸化 / 微分表示法 / イメージング法 / タンパク質キナーゼ / リン酸化部分ペプチド抗体 / 瞬目反射法 / 小脳中位核 / 視交叉上核 / Synaphin / ノルアドレナリン / 赤外線顕微鏡 / 共焦点レーザー顕微鏡 / 1分子可視化 / 1分子生化学 / エンドソーム / シナプトソーム / オルガネラ / 脳 / 情報処理 / 神経回路形成 / 計測技術 / 細胞シグナリング / 再構成 / プローブ顕微鏡 / 超顕微技術 / ナノメートル / 1分子の可視化 / 細胞内シグナル分子 / 可視化のダイナミックス / バイオイメージング / ポストゲノム / 領域間インターフェース / 物理化学 / 薬剤学 / 構造生物学 / 分析化学 / プロテオミックス / セロミックス / 薬学 / 薬学教育 / 共用試験 / OSCE / 実務実習 / CBT / 6年制薬学教育 / 分野別第三者教育評価 / 評価 / 評価基準 / 評価ガイドライン / 薬剤師養成 / 薬学会大学人会議 / 神経科学 / 学習 / 行動学 / 脳・神経 / ホスファチジルイノシトール2リン酸の加水分解 / ホスホリパーゼC / Caチヤネル阻害毒 / Caチヤネルの分類 / Caチヤネルの機能 / リン脂質平面膜 / イオンポンプ / 情報伝達 / 生体膜機能素子 / 合成ペプチド / クライオ電子顕微鏡 / コンピュ-タ-シミュレ-ション / イオンチャンネル / Phospholipid Planar Bilayer / Ion Pump / Signal Transduction / Functional Membrane Protein / Synthetic Peptide / Cryo-Electron Microscopy / Computer Simulation / 共焦点レ-ザ顕微鏡 / カルシウムシグナル / 時間分解顕微測光 / カシウムATPase / Dualーview顕微鏡 / 膜流動性 / 免疫応答 / カルシウムATPase / パルスレ-ザ顕微鏡 / 蛋白質前駆体 / 全重水素化リン脂質 / クロライドチャネル / 血小板 / 金コロイド / Confocal Microscope / Calcium Signal / Time-resolved Microscope / Ca^<2+>-ATPase / Dual-view Microscope / Membrane Fluidity / Immune Responses / 高次構造 / 動的構造 / モデルチャネル / パッチクランプ / 分子生物学 / クライオ電顕 / 分子動力学 / 動的構造機能連関 / クローニング / チャネル蛋白質 / 電気生理学 / 合成チャネル / Ion channels / Higher order structure / Dynamical structure / Model channel / Patch clamp / Molecular biology / Cryo-electron microscopy / Cキナーゼ / トランスロケーション / CaMキナーゼ / シナプトタグミン / 光トランスダクション / 瞬目反射反応 / 新しいリン酸化法 / LTP / ウニ卵 / GH_3細胞 / protein kinase C / translocation / CaM kinase II / Synaptotagmin / phototransduction / Eye blinks reflex / ^<32>P labelling of living cell / cyclic nucleotide sensitive channel / 薬物吸収 / 創薬研究 / 吸収・透過 / 顕微鏡光学技術 / 経皮吸収 / 初回通回効果 / 高分子薬物 / Durg absorption / Confocal Microscopy / Scanning Probe Microscopy / Investigation of New Drug / Absorption and Transportion / Optical microscopic technique / 電子スピン共鳴(ESR) / フリーラジカル / 活性酸素 / 生体計測 / ESR-CT / ラット / 関節炎 / 糖尿病 / ニトロキシドラジカル / 診断機器 / SOD / 遺伝子組換えマウス / ESR / 活性酵素 / 画像解析 / 生体レドックス / 一酸化窒素 / 電子スビン共鳴(ESR) / 一酸化窒素(NO) / Electron Spin Resanance / Free Radical / Active Oxygen / in vivo / 生体膜 / 脂質膜 / 膜タンパク質 / 分子内相互作用 / 秩序構造形成 / 高次構造生体膜機能 / Biological membrane / Lipid bilayer / Membrane protein / Intramolecular / interaction / Structure formation / Higer order structure Less

Learning and Memory Performance of Alzheimer Disease Mouse Model with Mutant Human Tau ProteinPrincipal Investigator
- Principal Investigator
  
  Kirino Yutaka
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokushima Bunri University
An Attempt to Detect a Neural Activity Change during Eyeblink Conditioning in Monkeys with PET ImagingPrincipal Investigator
- Principal Investigator
  
  KIRINO YUTAKA
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokushima Bunri University
マウス瞬目反射学習に小脳は不要か?Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokushima Bunri University
小脳特異的分子欠損マウスを用いた学習メカニズム多重性とその制御機構の解明
- Principal Investigator
  
  川原茂敬
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
  The University of Tokyo
小脳特異的分子欠損マウスを用いた脳システム階層的相互作用の解析Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
A study on molecular and neural mechanism of eyeblink conditioningPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokushima Bunri University
  The University of Tokyo
薬学実務実習開始前の臨床能力評価方法に関する調査研究
- Principal Investigator
  
  望月正隆
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoritsu University of Pharmacy
薬剤師養成を目的とした大学教育に対する外部評価システムの構築のための基盤研究
- Principal Investigator
  
  井上圭三
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
ポストゲノムにおける領域間インターフェースの構築と次世代薬学研究者の育成
- Principal Investigator
  
  中西守
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University
内在性誘導型アンチセンストランスクリプトによる遺伝子調節機構の解明Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
Molecular neurobiology of olfactory learning in the land slugPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
ナメクジ嗅覚-味覚連合学習およびマウス瞬目反射連合学習の分子神経機構Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
新規高感度膜電位感受性色素の探索と細胞内染色法の開発Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
ナメクジにおける学習特異的蛋白質LAPS18の機能解析と連合学習の分子神経機構Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of memory formation and readout in the slugPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  THE UNIVERSITY OF TOKYO
The development of the model animals for, and the analysis of the pathogenic mechanism of Lambert-Eaton myasthenic syndromePrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  THE UNIVERSITY OF TOKYO
脳研究における生物物理学的アプローチの探索Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
モルモット単離小脳を用いたin vitro学習系の開発Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
脳研究における生物物理学的アプローチの探索
- Principal Investigator
  
  曽我部正博
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
細胞内シグナル分子の捕捉と可視化のダイナミックス
- Principal Investigator
  
  中西守
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya City University
Simple nervous system approach to the mechanisms of associative learningPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
Development of An Animal Model of the Lambert-Eaton Myasthenic SyndromePrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokyo
脳研究における生物物理学的アプローチの探索
- Principal Investigator
  
  葛西道生
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Osaka University
細胞情報変換・制御の可視化解析
- Principal Investigator
  
  中西守
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya City University
A Study on Ca Influx and Acetyulcholine Release in the Presynaptic Terminals of Cholinergic Nerve of the Electric OrganPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
神経活動によるシナプスの強化・固定のメカニズム
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Waseda University
脂質平面膜を用いた膜電位感受性色素の評価系の開発とその応用Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
神経伝達物質放出の調節機構
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
若手研究者育成のための教育プログラムの開発
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Waseda University
Molecular Mechanism of Neuroplasticity for Learning
- Principal Investigator
  
  YOSHIOKA Toru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Sch.of Human Sci.Waseda Univ.
Bioimaging and theory for drug absorption in living cells
- Principal Investigator
  
  NAKANISHI Mamoru
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Nagoya City University
The mechanism of neurotransmitter release and its control using electric organ synapse of electric rayPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
Development of in vivo ESR for detecting free radicals in human living body
- Principal Investigator
  
  UTSUMI Hideo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
連合学習の比較分子生物学
- Principal Investigator
  
  川合述史
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Jichi Medical University
PIONEERING RESEARCH ON THE DYNAMICAL ASPECT OF STRUCTURE-FUNTION RELATIONSHIP IN ION CHANNELS
- Principal Investigator
  
  SOKABE Masahiro
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
脳・神経細胞におけるインパルス・シグナリングの分子機構
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
細胞膜から核へのインフォメーションフローに関する総合的研究Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kyushu University
Mechanism of the Release of Acetylcholine from Presynaptic Nerve Terminals Isolated from Electric Organ of Japanese Electric RayPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
  Kyushu University
脳神経細胞におけるインパルスシグナリングの分子機構
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
細胞膜から核へのインフォメ-ションフロ-に関する総合的研究Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Kyushu University
Development of a Method for Measuring Oxyngen Concentration in Biological Systems by Means of ESRPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokyo
  Kyushu University
Analysis of Functional Membrane Proteins by Planar Phospholiped Bilayers.
- Principal Investigator
  
  HIRATA Hajime
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  分子遺伝学・分子生理学
- Research Institution
  Himeji Institute of Technology, Faculty of Science
  Jichi Medical University
Membrane Structures for Bio-communication
- Principal Investigator
  
  NAKANISHI Mamoru
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  Nagoya City University
「脳・神経細胞におけるインパルス・シグナリングの分子機構」
- Principal Investigator
  
  YOSHIOKA Toru
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
「脳・神経細胞におけるインパルス・シグナリングの分子機構」の推進
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Waseda University
Reconstitution of Ion Channels from Cardiac Sarcolemmal MembranesPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  生物物性学
- Research Institution
  Kyushu University
再構成膜系における筋小胞体カルシウムポンプのエナジェティックスPrincipal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Studies on Interactions of Flectric Field and BiomembranesPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  Kyushu University
イオン輸送体タンパク質の巨大ベシクルへの再構成とその応用Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Mechanism of Presynaptic Function as Studied Using Giant SynaptosomesPrincipal Investigator
- Principal Investigator
  
  KIRINO Yutaka
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
新しい情報変換分子の検索
- Principal Investigator
  
  吉岡亨
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Yokohama City University
巨大ベシクル再構成膜法の確立とそれを用いたカルシウム輸送機構の研究Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
Strcture Formation of Biological Membranes
- Principal Investigator
  
  MITAKU Shigeki
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  Tokyo University of Agriculture and Technology
巨大ベシクル再構成膜法の確立とそれを用いたカルシウム輸送機構の研究Principal Investigator
- Principal Investigator
  
  桐野豊
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  The University of Tokyo

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All Journal Article Presentation Book

[Book] 記憶のしくみ　（上）2013
- Author(s)
  小西史朗、桐野　豊、伊藤悦朗、宋　時栄（訳書）
- Total Pages
  298
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-24590068
[Book] 記憶のしくみ　(下）2013
- Author(s)
  小西史朗、桐野　豊、伊藤悦朗、宋　時栄　(訳書）
- Total Pages
  300
- Publisher
  講談社
- Data Source
  KAKENHI-PROJECT-24590068
[Book] 生物物理学ハンドブック2007
- Author(s)
  石渡信一,桂勲,桐野豊,美宅茂樹編
- Total Pages
  662
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Traumastic Brain Injury by Weight-Drop Methos Causes Transient Amyloid-β Deposition and Acute Cognitive Deficits in Mice2019
- Author(s)
  H. Shishido, M. Ueno, K. Sato, M. Matsumura, Y. Toyoda, Y. Kirino, T. Tamiya, N. Kawai, Y. Kishimoto
- Journal Title
  
  Behavioural Neurology
  
  Volume: 2019
- DOI
  10.1155/2019/3248519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08215
[Journal Article] Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer’s disease.2016
- Author(s)
  Hajime Shishido*, Yasushi Kishimoto*, Nobuyuki Kawai, Yasunori Toyota, Masaki Ueno, Takashi Kubota, Yutaka Kirino, Takashi Tamiya.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 629 Pages: 62-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08215
[Journal Article] Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2.2016
- Author(s)
  Steven A. Connor*, Ina Ammendrup-Johnsen*, Allen W. Chan*, Yasushi Kishimoto*, Chiaki Murayama, Naokazu Kurihara, Atsushi Tada, Yuan Ge, Hong Lu, Ryan Yan, Jeffrey M. LeDue, Hirotaka Matsumoto, Hiroshi Kiyonari, Yutaka Kirino,... Tohru Yamamoto, Ann Marie Craig.
- Journal Title
  
  Neuron
  
  Volume: 91 Pages: 1052-2068
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08215
[Journal Article] Ameliorative effect of membrane-associated estrogen receptor G protein coupled receptor 30 activation on object recognition memory in mouse models of Alzheimer’s disease2016
- Author(s)
  Takashi Kubota, Hiroshi Matsumoto, Yutaka Kirino.
- Journal Title
  
  Journal of Pharmacological Science
  
  Volume: 131 Pages: 219-222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08215
[Journal Article] Implicit memory in monkeys : Development of a delay eyeblink conditioning system with parallel electromyographic and high-speed video measurements.2015
- Author(s)
  Kishimoto Y, Yamamoto S, Suzuki K, Toyoda H, Kano M, Tsukada H, Kirino Y
- Journal Title
  
  PLoS ONE
  
  Volume: 10
- DOI
  10.1371/journal.pone.0129828
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07910, KAKENHI-PROJECT-24590068, KAKENHI-PROJECT-25000015
[Journal Article] Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol.2015
- Author(s)
  Kishimoto Y, Cagniard B, Yamazaki M, Nakayama J, Sakimura K, Kirino Y, Kano M
- Journal Title
  
  Front Behav Neurosci
  
  Volume: 9 Pages: 134-134
- DOI
  10.3389/fnbeh.2015.00134
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590068, KAKENHI-PROJECT-24590133, KAKENHI-PROJECT-15K07910, KAKENHI-PROJECT-24240048, KAKENHI-PROJECT-25000015
[Journal Article] Inhibition of MAO-A and stimulation of behavioural activities in mice by the inactive prodrug form of the anti-influenza agent oseltamivir.2013
- Author(s)
  Hiasa M*, Isoda Y*, Kishimoto Y *, Saitoh K, Kimura Y, Kanai M, Shibasaki M, Hatakeyama D, Kirino Y, Kuzuhara T
- Journal Title
  
  Br. J. Pharmacol.
  
  Volume: 169 Pages: 115-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590068
[Journal Article] Presenilin 2 mutation accelerates the onset of impairment in trace eyeblink conditioning in a mouse model of Alzheimer's disease overexpressing human mutant amyloid precursor protein.2013
- Author(s)
  Kishimoto Y, Kirino Y
- Journal Title
  
  Neurosci. Lett.
  
  Volume: 538 Pages: 15-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590068
[Journal Article] Early impairment in a water-finding test in a longitudinal study of the Tg2576 mouse model of Alzheimer's disease.2013
- Author(s)
  Kishimoto Y, Higashihara E, Fukuta A, Nagao A, Kirino Y
- Journal Title
  
  Brain Res.
  
  Volume: 1491 Pages: 731-739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590068
[Journal Article] Age-dependent impairment of eyeblink conditioning in prion protein-deficient2013
- Author(s)
  Kishimoto Y, Hirono M, Atarashi R, Sakaguchi S, Yoshioka T, Katamine S, Kirino
- Journal Title
  
  PLOS ONE
  
  Volume: 8
- DOI
  10.1371/journal.pone.0060627
- NAID
  120006985917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24590068, KAKENHI-PROJECT-24590133
[Journal Article] Dual involvement of G-substrate in motor learning revealed by gene deletion2009
- Author(s)
  Endo, S., Shutoh, F., Dinh, T. L., Okamoto, T., Ikeda, T., Suzuki, M., Kawahara, S., Yanagihara, D., Sato, Y., Yamada, K., Sakamoto, T., Kirino, Y., Hartell, N. A., Yamaguchi, K., Itohara, S., Nairn, A. C., Greengard, P., Nagao, S., Ito M.
- Journal Title
  
  Proc Natl Acad Sci USA 106 (9)
  
  Pages: 3525-3530
- NAID
  120006399303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659010
[Journal Article] Dual involvement of G-substrate in motor learning revealed by gene deletion2009
- Author(s)
  Endo, S., Shutoh, F., Dinh, T. L., Okamoto, T., Ikeda, T., Suzuki, M., Kawahara, S., Yanagihara, D., Sato, Y., Yamada, K., Sakamoto, T., Kirino, Y., Hartell, N. A., Yamaguchi, K., Itohara, S., Nairn, A. C, Greengard, P., Nagao, S., Ito M.
- Journal Title
  
  Proc Natl Acad Sci USA 106(9)
  
  Pages: 3525-3530
- NAID
  120006399303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Dual involvement of G-substrate in motor learning revealed by gene deletion2009
- Author(s)
  Endo, S., Shutoh, F., Dinh, T. L., Okamoto, T., Ikeda, T., Suzuki, M., Kawahara, S., Yanagihara, D., Sato, Y., Yamada, K., Sakamoto, T., Kirino, Y., Hartell, N. A., Yamaguchi, K., Itohara, S., Nairn, A. C., Greengard, P., Nagao, S. and Ito, M.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 106
  
  Pages: 3525-3530
- NAID
  120006399303
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Nitric oxide is involved in appetitive but not aversive olfactory learning in the land slug Limax valentianus2008
- Author(s)
  Yabumoto, T., Takanashi, F., Kirino, Y., Watanabe, S.
- Journal Title
  
  Learn Mem 15(4)
  
  Pages: 229-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Nitric oxide is involved in appetitive but not aversive olfactory learning in the land slug Limax valentianus2008
- Author(s)
  Yabumoto, T., Takanashi, F., Kirino, Y., Watanabe, S.
- Journal Title
  
  Learn Mem 15(4)
  
  Pages: 229-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659010
[Journal Article] Neural and molecular mechanisms of microcognition in Limax2008
- Author(s)
  Watanabe, S., Kirino, Y. and Gelperin, A.
- Journal Title
  
  Learn. Mem. 15
  
  Pages: 633-642
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Neural and molecular mechanisms of microcognition in Limax2008
- Author(s)
  Watanabe, S., Kirino, Y., Gelperin, A.
- Journal Title
  
  Learn Mem 15(9)
  
  Pages: 633-642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Neural and molecular mechanisms of microcognition in Limax2008
- Author(s)
  Watanabe, S., Kirino, Y., Gelperin, A.
- Journal Title
  
  Learn Mem 15(9)
  
  Pages: 633-642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659010
[Journal Article] Impaired motor functions in mice lacking the RNA-binding protein Hzf2007
- Author(s)
  Iijima, T., Ogura, H., Takatsuki, K., Kawahara, S., Wakabayashi, K., Nakayama, D., Fujioka, M., Kimura, Y., Bernstein, A., Okano, H. J., Kirino, Y. and Okano, H.
- Journal Title
  
  Neurosci. Res. 58
  
  Pages: 183-189
- NAID
  10024415208
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Selective calcium imaging of olfactory interneurons in a land mollusk2007
- Author(s)
  Watanabe, S. and Kirino, Y.
- Journal Title
  
  Neurosci. Lett. 417
  
  Pages: 246-249
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Change of Purkinje cell activity during classical conditioning in decerebrate guinea pig2006
- Author(s)
  Kotani, S., Kawahara, S. and Kirino, Y.
- Journal Title
  
  Brain Res. 1068
  
  Pages: 70-81
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] A novel kruppel-like factor is induced by neuronal activity and by sensory input in the central nervous system of the terrestrial slug2006
- Author(s)
  Fukunaga, S., Matsuo, R., Hoshino, S. and Kirino, Y.
- Journal Title
  
  Limax valentianus, J. Neurobiol. 66
  
  Pages: 169-181
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] In vitro odor-aversion conditioning in a terrestrial mollusk2006
- Author(s)
  Inoue, T., Murakami, M., Watanabe, S., Inokuma, Y. and Kirino, Y,
- Journal Title
  
  J. Neurophysiol. 95
  
  Pages: 3898-3903
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Hippocampal CA3 NMDA receptors are crucial for adaptive timing of trace eyeblink conditioned response2006
- Author(s)
  Kishimoto, Y., Nakazawa, K., Tonegawa, S., Kirino, Y. and Kano, M.
- Journal Title
  
  J. Neurosci. 26
  
  Pages: 1562-1570
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Systems consolidation requires postlearning activation of NMDA receptors in the medial prefrontal cortex in trace eyeblink conditioning2006
- Author(s)
  Takehara-Nishiuchi, K., Nakao, K., Kawahara, S., Matsuki, N. and Kirino, Y.
- Journal Title
  
  J. Neurosci. 26
  
  Pages: 5049-5058
- NAID
  120006399305
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] NMDA receptors play important roles in acquisition and expression of the eyeblink conditioned response in glutamate receptor subunitδ2 mutant mice2005
- Author(s)
  Kato, Y., Takatsuki, K., Kawahara, S., Fukunaga, S., Mori, H., Mishina, M. and Kirino, Y.
- Journal Title
  
  Neuroscience 135
  
  Pages: 1017-1023
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Characterization of hippocampal theta rhythm in wild-type mice and glutamate receptor subunitδ2 mutant mice during eyeblink conditioning with a short trace interval2005
- Author(s)
  Takatsuki, K., Kawahara, S., Mishina, M. and Kirino, Y.
- Journal Title
  
  Brain Res. 1063
  
  Pages: 159-167
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Role of hippocampal NMDA receptors in trace eyeblink conditioning2005
- Author(s)
  Sakamoto, T., Takatsuki, K., Kawahara, S., Kirino, Y., Niki, H. and Mishina, M.
- Journal Title
  
  Brain Res. 1039
  
  Pages: 130-136
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] NMDA receptor-dependent processes in the medial prefrontal cortex are important for acquisition and the early stage of consolidation during trace but not delay eyeblink conditioning2005
- Author(s)
  Takehara-Nishiuchi, K., Kawahara, S., and Kirino, Y.
- Journal Title
  
  Learn. Mem. 12
  
  Pages: 606-614
- NAID
  120006399290
- Data Source
  KAKENHI-PROJECT-17209002
[Journal Article] Odor-evoked responses in the olfactory center neurons in the terrestrial slug2004
- Author(s)
  Murakami M, Watanabe S, Inoue T, Kirino Y
- Journal Title
  
  J Neurobiol 58
  
  Pages: 369-378
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] Distribution of serotonin-like immunoreactive neurons in the slug Limax valentianus2004
- Author(s)
  Shirahata T, Watanabe S, Kirino Y
- Journal Title
  
  Cell Tiss Res 315
  
  Pages: 285-290
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] Onset of Amnesia Is Delayed with a Decrease in Inhibition of Protein Synthesis durining Odor-taste Associative Learning in the Terrestrial Slug Limax Valentianus2004
- Author(s)
  Yasui K, Matsuo R, Kirino Y
- Journal Title
  
  Zoological Science 21
  
  Pages: 1163-1166
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] Optical recording of oscillatory neural activities in the molluscan brain2004
- Author(s)
  Watanabe S, Shimozono, S, Kirino Y
- Journal Title
  
  Neurosci Lett 349
  
  Pages: 147-150
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] 連合学習 -瞬目反射条件付けと上位中枢の関与-2004
- Author(s)
  川原茂敬, 桐野豊
- Journal Title
  
  蛋白質核酸酵素 49
  
  Pages: 493-498
- Data Source
  KAKENHI-PROJECT-15390010
[Journal Article] 連合学習 -瞬目反射条件付けと上位中枢の関与-2004
- Author(s)
  川原茂敬, 桐野豊
- Journal Title
  
  蛋白質核酸酵素増刊号「神経回路の機能発現のメカニズム」 49
  
  Pages: 493-498
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390010
[Journal Article] Modulation of two oscillatory networks in the peripheral olfactory system by gamma-aminobutyric acid, glutamate and acetylcholine in the terrestrial slug Limax marginatus2004
- Author(s)
  Ito I, Kimura T, Watanabe S, Kirino Y, Ito E
- Journal Title
  
  J Neurobiol 59
  
  Pages: 304-318
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] Impairment of olfactory discrimination by blockade of nitric oxide activity in the terrestrial slug Limax valentianus2004
- Author(s)
  Sakura M, Kabetani M, Watanabe S, Kirino Y
- Journal Title
  
  Neurosci Lett 370
  
  Pages: 257-261
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] The N-methyl-D-aspartate (NMDA)-type glutamate receptor GluR epsilon2 is important for delay and trace eyeblink conditioning in mice2004
- Author(s)
  Takehara K, Kawahara S, Munemoto Y, Kuriyama H, Mori H, Mishina M, Kirino Y
- Journal Title
  
  Neurosci Lett 364
  
  Pages: 43-47
- NAID
  120006399291
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] In vitro study of odor-evoked behavior in the terrestrial mollusk2004
- Author(s)
  Inoue T, Inokuma Y, Watanabe S, Kirino Y
- Journal Title
  
  J Neurophysiol 91
  
  Pages: 372-381
- Data Source
  KAKENHI-PROJECT-16659011
[Journal Article] ナメクジの匂い学習のメカニズム2003
- Author(s)
  渡辺恵, 桐野豊
- Journal Title
  
  Aroma Research 4
  
  Pages: 2-7
- NAID
  40005713277
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390010
[Presentation] タウタンパク質発現期間依存的な記憶およびタウタンパク質代謝の障害2020
- Author(s)
  窪田剛志、岸本泰司、桐野豊
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] Age-dependent impairment of memory, neurofibrillary tangle formation and clearance in a mouse model of tauopathy2019
- Author(s)
  Takashi Kubota, Yutaka Kirino
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] アルツハイマー病モデルマウスのα7ニコチン性アセチルコリン受容体を介した学習改善作用におけるmicroRNA-134の効果2017
- Author(s)
  窪田剛志、桐野豊
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] シナプス形成抑制因子ＭＤＧＡ２のヘミ欠損は興奮/抑制バランスの興奮側へのシフトによるＡＳＤ様の社会性行動異常をもたらす2017
- Author(s)
  2.山本融、Connor A Steven、岸本泰司、Ammendrup-Johnsen Ina、栗原直和、村山千明、尾嶋大喜、Hossain Razib、鈴木利治、桐野豊、Craig Ann Marie
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] Traumatic brain injury accelerates amyloid-beta deposition and impairs learning and memory in the triple-transgenic mouse model of Alzheimer’s disease2017
- Author(s)
  Yutaka Kirino, Hajime Shishido, Nobuyui Kawai, Yasunori Toyota, Takashi Tamiya, Takashi Kubota, Masaki Ueno, Yasushi Kishimoto
- Organizer
  Society for Neuroscience Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] MDGA2は興奮性シナプス形成抑制因子であり、そのヘミ欠損は興奮性の亢進とASD様の行動異常をもたらす2017
- Author(s)
  山本融、Connor A Steven、岸本泰司、Ammendrup-Johnsen Ina、栗原直和、村山千明、尾嶋大喜、Hossain Razib、鈴木利治、桐野豊、Craig Ann Marie
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] Altered social and cognitive functions upon haploinsufficiency of the excitatory synaptic suppressor MDGA2 in a mouse model of autism2016
- Author(s)
  岸本泰司、栗原直和、村山千明、多田篤史、桐野豊、山本融
- Organizer
  日本生物物理学会中国四国支部大会
- Place of Presentation
  高松市
- Year and Date
  2016-05-28
- Data Source
  KAKENHI-PROJECT-16K08215
[Presentation] アルツハイマー病モデルマウスの物体認識記憶におけるmicroRNA-132の2相性の効果2016
- Author(s)
  窪田剛志、桐野豊
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜　横浜市
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] Task-specific impairment of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase2015
- Author(s)
  Yasushi Kishimoto, Barbara Cagniard, Maya Yamazaki, Junko Nakayama, Kenji Sakimura, Yutaka Kirino, Masanobu Kano
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢大学　金沢市
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] サルにおける瞬目反射条件付け: 筋電位測定法と高速イメージング法を用いた瞬目反射条件づけ方法の開発とその評価2013
- Author(s)
  桐野豊、山本茂幸、鈴木一隆、豊田晴義、狩野方伸、塚田秀夫、岸本泰司
- Organizer
  第36回日本神経科学大会•第56回日本神経化学会大会•第23回日本神経回路学会大会合同大会
- Place of Presentation
  京都市　京都国際会館
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] PS2Tg2576アルツハイマーモデルマウスの認知機能障害に対するメマンチンの効果2013
- Author(s)
  岸本泰司、松村政久、佐藤加奈、長井美佳、桐野　豊
- Organizer
  第52回日本薬学会•日本薬剤師会•日本病院薬剤師中国四国支部学術大会
- Place of Presentation
  松山市　松山大学
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] モノアシルグリセロールリパーゼ欠損マウスにおける海馬依存性記憶機能の包括的評価2013
- Author(s)
  １．岸本泰司、Barbara Cagniard、山崎真弥、中山順子、崎村建司、桐野豊、狩野方伸
- Organizer
  第36回日本神経科学大会•第56回日本神経化学会大会•第23回日本神経回路学会大会合同大会
- Place of Presentation
  京都市　京都国際会館き
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] サルにおける瞬目反射条件づけ：筋電位測定法と高速イメージング法を用いた瞬目反射条件づけ方法の開発とその評価2013
- Author(s)
  桐野　豊、岸本泰司、山本茂幸、鈴木一隆、豊田晴義、狩野方伸、塚田秀夫
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] Involvement of membrane-associated estrogen receptor GPR30 in the object recognition memory in Alzheimer's disease mouse models2013
- Author(s)
  窪田剛志、松元博志、桐野豊
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡市　福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] テトラサイクリン遺伝子発現誘導系を利用した記憶学習の分子過程の解明2009
- Author(s)
  岸本泰司, 原田武志, 平井良枝, 中尾晴美, 中尾和貴, 饗場篤, 桐野豊
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] テトラサイクリン遺伝子発現誘導系を利用した記憶学習の分子過程の解明2009
- Author(s)
  岸本泰司,原田武志,平井良枝,中尾晴美,中尾和貴,饗場篤,桐野豊
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 小脳依存性学習に対するアナンダミド分解酵素阻害の効果2009
- Author(s)
  中山順子,奥郁子,岸本泰司,桐野豊
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 小脳依存性学習に対するアナンダミド分解酵素阻害の効果2009
- Author(s)
  中山順子, 奥郁子, 岸本泰司, 桐野豊
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] 肥満モデルマウスの瞬目反射条件付け学習におけるカンナビノイドシステムの関与2008
- Author(s)
  窪田剛志,桐野豊
- Organizer
  第45 回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 野生型マウスの加齢による聴性脳幹反応の変化2008
- Author(s)
  北村美一郎, 桐野豊
- Organizer
  第1回日本生物物理学会中国四国支部大会
- Place of Presentation
  高知
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] 肥満モデルマウスの瞬目反射条件付け学習におけるカンナビノイドシステムの関与2008
- Author(s)
  窪田剛志, 桐野豊
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] 野生型マウスC57BL/6Jにおける聴性脳幹反応の加齢に伴う変化2008
- Author(s)
  北村美一郎, 桐野豊
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 野生型マウスC57BL/6Jにおける聴性脳幹反応の加齢に伴う変化2008
- Author(s)
  北村美一郎, 桐野豊
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] モノアシルグリセロールリパーゼ(MGL)阻害による瞬目反射条件付け記憶の消去障害2008
- Author(s)
  岸本泰司, 桐野豊
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] Tet-OFF遺伝子発現システムを用いた小脳学習におけるMAPK/ERK kinase 1の機能解析2008
- Author(s)
  岸本泰司, 原田武志, 平井良枝, 中尾晴美, 中尾和貴, 桐野豊, 饗場篤
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] モノアシルグリセロールリパーゼ(MGL)阻害による瞬目反射条件付け記憶の消去障害2008
- Author(s)
  岸本泰司,桐野豊
- Organizer
  第31 回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 肥満モデルマウスの瞬目反射条件付け学習におけるカンナビノイドシステムの関与2008
- Author(s)
  窪田剛志, 桐野豊
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] Tet-OFF遺伝子発現システムを用いた小脳学習におけるMAPK/ERK kinase 1 の機能解析2008
- Author(s)
  岸本泰司, 原田武志, 平井良枝, 中尾晴美, 中尾和貴, 桐野豊, 饗場篤
- Organizer
  第45回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] 運動記憶形成における小脳顆粒細胞シナプス機能の解明2008
- Author(s)
  岸本泰司, 和田教男, 桐野豊, 狩野方伸, 中西重忠
- Organizer
  第1回日本生物物理学会中国四国支部大会
- Place of Presentation
  高知
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] モノアシルグリセロールリパーゼ(MGL)阻害による瞬目反射条件付け記憶の消去障害2008
- Author(s)
  岸本泰司, 桐野豊
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] 運動記憶形成における小脳頼粒細胞シナプス機能の解明2008
- Author(s)
  岸本泰司, 和田教男, 桐野豊, 狩野方伸, 中西重忠
- Organizer
  第1回日本生物物理学会中国四国支部大会
- Place of Presentation
  高知
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-19659010
[Presentation] 野生型マウスの加齢による聴性脳幹反応の変化2008
- Author(s)
  北村美一郎, 桐野豊
- Organizer
  第1回日本生物物理学会中国四国支部大会
- Place of Presentation
  高知
- Year and Date
  2008-06-16
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] Tet-OFF 遺伝子発現システムを用いた小脳学習におけるMAPK/ERK kinase 1 の機能解析2008
- Author(s)
  岸本泰司,原田武志,平井良枝,中尾晴美,中尾和貴,桐野豊,饗場篤
- Organizer
  第45 回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 野生型マウスC57BL/6Jにおける聴性脳幹反応の加齢に伴う変化2008
- Author(s)
  北村美一郎,桐野豊
- Organizer
  第45 回日本生物物理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 若齢および老齢マウスの瞬目反射条件付けに対するNMDA 受容体阻害薬の効果2007
- Author(s)
  鈴木令子,王芳,浅木敏之,勝浦五郎,桐野豊,川原茂敬
- Organizer
  第80 回日本薬理学会年会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 肥満モデルマウスの瞬目反射条件付け学習におけるカンナビノイドの関与2007
- Author(s)
  窪田剛志,川原茂敬,桐野豊
- Organizer
  第127 回日本薬学会年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] 加齢によるマウス聴性脳幹反応の変化2007
- Author(s)
  北村美一郎,桐野豊
- Organizer
  第45 回日本生物物理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] Eyeblink conditioning and Morris water maze in senescence-accelerated mice SAMP82006
- Author(s)
  Kirino, Y., Kato, Y., Kawahara, S., Sakaguchi, I., Ishibashi, C., Takeyama, C., Takahara, Y., Katsuura, G.
- Organizer
  36th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-17209002
[Presentation] All-transレチノイン酸の短期投与がアルツハイマー病モデルマウスの認知•行動に及ぼす効果
- Author(s)
  栗原直和、桐野豊、窪田剛志、岸本泰司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] α7 ニコチン性アセチルコリン受容体作動薬の作業記憶増強作用におけるマイクロRNA-134 の関与
- Author(s)
  窪田剛志、中島維大、桐野豊
- Organizer
  日本薬学会第134年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] Accelerated impairment of learning and memory by presenilin 2 mutation in APP transgenic mouse model of Alzheimer’s disease
- Author(s)
  Yutaka Kirino and Yasushi Kishimoto
- Organizer
  Annual Meeting 2014, Society for Neuroscience
- Place of Presentation
  Washington DC, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] ADモデルマウスの認知機能に対する慢性脳低還流の影響
- Author(s)
  澤西真由美、岸本泰司、豊田康則、田宮隆、河井信行、桐野豊
- Organizer
  日本薬学会第134年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24590068
[Presentation] アルツハイマー病モデルマウスの認知機能に対する外傷性脳損傷の影響
- Author(s)
  岸本泰司、宍戸肇、河井信行、上野正樹、窪田剛志、田宮隆、桐野豊
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24590068

1. YOSHIOKA Toru (70046027)

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KIRINO YUTAKA 桐野 豊

KIRINO Yutaka 桐野 豊

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Learning and Memory Performance of Alzheimer Disease Mouse Model with Mutant Human Tau ProteinPrincipal Investigator

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An Attempt to Detect a Neural Activity Change during Eyeblink Conditioning in Monkeys with PET ImagingPrincipal Investigator

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マウス瞬目反射学習に小脳は不要か?Principal Investigator

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小脳特異的分子欠損マウスを用いた脳システム階層的相互作用の解析Principal Investigator

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A study on molecular and neural mechanism of eyeblink conditioningPrincipal Investigator

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内在性誘導型アンチセンストランスクリプトによる遺伝子調節機構の解明Principal Investigator

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Molecular neurobiology of olfactory learning in the land slugPrincipal Investigator

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ナメクジ嗅覚-味覚連合学習およびマウス瞬目反射連合学習の分子神経機構Principal Investigator

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新規高感度膜電位感受性色素の探索と細胞内染色法の開発Principal Investigator

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ナメクジにおける学習特異的蛋白質LAPS18の機能解析と連合学習の分子神経機構Principal Investigator

KIRINO YUTAKA 桐野豊

KIRINO Yutaka 桐野豊