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KANEGASAKI Shiro  金ケ崎 士郎

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… Alternative Names

金ヶさき 士朗  カネガサキ シロウ

金ヶ崎 士郎  カネガサキ シロウ

金ケ崎 士郎  カネガサキ シロウ

金ヶ崎 七朗  カネガサキ シロウ

金ケ崎 士朗  カネガサキ シロウ

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Researcher Number 10012767
Affiliation (based on the past Project Information) *help 1998: 東京大学, 医科学系研究所, 教授
1986 – 1998: Professor, Institute of Medical Science, University of Tokyo,, 医科学研究所, 教授
1987: 東京大学, 医化学研究所, 教授
1986: 東京大学, 医科研, 教授
1986: 東大, 医科学研究所, 助教授
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology) / 細菌学 / 内科学一般 / Immunology
Except Principal Investigator
細菌学 / Hematology / Pathological medical chemistry / Immunology / 内科学一般 / 代謝生物化学
Keywords
Principal Investigator
好中球 / スーパーオキシド / 慢性肉芽腫症 / CGD / 活性酸素 / シトクロム / Bリンパ球 / 食細胞 / スーパーオキシドアニオン / レトロウイルスベクター … More / p47-phox / Neutrophils / Tリンパ球 / p67 / p47 / gp91 / gene therapy / 遺伝子治療 / superoxide / gp91-phox / Super oxide / 好酸球 / CD30 / ホジキン病 / b型シトクロム / 47kDa蛋白質 / シトクロ-ム / ス-パ-オキシドアニオン / 酸素代謝 / O_2^-(スーパーオキサイド)NADPHオキシデース / 不飽和脂肪酸 / 飽和脂肪酸 / 脂肪酸 / MDR gene / chronic granulomatous disease / retroviral vector / superoxide generation / B細胞株 / MDR / 遺伝子導入 / MDR遺伝子 / cytochrome / retroviral vectors / B cell lines / inherited disorder / phagocytes / 薬剤選択 / B細胞 / 先天性異常 / phagocyte / beta-actin / eosinophil / neutrophil / Chronic granulomatous disease / 遺伝性疾患 / 細胞内アクチン異常症 / 白血球粘着不全症 / 高IgE症候群 / アポトーシス / β-アクチン / βアクチン / Immunocompromised / Vector / B lymphocytes / p67-phox / インベージン / b型のシトクロム / リポソーム / ベェクター / 合成ペプチド / インベ-ジン / 慢性肉芽腫症患者 / ベクター / 白血球 / 遺伝子 / Phagocytes / NADPH / Synthetic peptides / Cytochrome / 電気穿孔法 / U937細胞 / Cytochrome b_<558> / Neutrophil functions / 47-kDa Cytosolic protein / B lymphocyte / O_<2->-generating sytem / Neutrophil / Host defense mechanism / 電子スピン共鳴 / 重傷熱傷患者 / スパ-オキシドアニオン / 殺菌 / 好中球機能 / 易感染性 / O_<2->産生系 / 感染防御 / Spin-trap ESR / Chronic Granulomatous Disease / Lymphocytes / Superoxide anion / Macrophages / ERS / ヒドロキシルラジカル / ス-パ-オキシド / 単球 / リンパ球 / 慢性肉芽胞症(CGD) / マクロファ-ジ / スピントラップESR / 抗原刺激 / 遺伝子クローニング / ジャーカット細胞 / 糖結合性蛋白 / エカレクチン / ガレクチン / 好酸球走化性因子 / ホジキソ病 / Tリンパ腫 / ALCL / Bリンパ腫 / リンフォマトイド・パピュロ-シス / マクロファージ / 悪性リンパ腫 / リンパ腫 / CD30陽性細胞 / 細胞質因子 / RFLP解析 / 65kDa蛋白質 / 形質膜 / 電子伝達系 / ファゴゾ-ム / 先天性免疫不全 … More
Except Principal Investigator
活性酸素 / Acetyl-LDL / LDL / EBV-BCL / CGD / DMPO / マクロファ-ジ / Zymosan / PMA / 好中球 / ミエロペルオキシダーゼ / Bリンパ球 / Middle ear effusion cell / Kupffer cell / Mactophage / Neutrophil / LPS deacylation / Endotoxin / 3-OHミリスチン酸 / ミリスチン酸 / 抗LPSIgG / 牛好中球のLPS取り込み / クッパー細胞のLPS取り込み / クッパー細胞によるLPSの脱アシル化 / 内毒素の分解 / 中耳腔浸潤細胞 / LPS / 中耳滲潤細胞 / グッパ-細胞 / LPS脱アシル化 / 内毒素 / bovine papilloma virus / gene engineering / cDNA chromosomal gene / interferon- <gamma> / granulocyte colony stimulating factor / hemopoiesis / 遺伝子工学 / 染色体遺伝子 / cDNA / 顆粒球コロニー刺激因子 / インターフェロンγ / 造血作用 / 血液細胞 / superoxide / superoxide-generating system / Ig class switching / surface immunoglobulin / B lymphocytes / Lg class switch / surface Lg / CGD(慢性肉芽腫症) / 活性酸素産生系 / Ig class switch / surface Ig / Superoxide / ESR spin-trapping / Macrophages / Neutrophils / Phagocytosis / Hydroxyl radical / 8ーハイドロキシグアニン / スピントラップ / ヒドロキシラジカル / チモ-ザン / ESRスピントラップ法 / ビドロキシラジカル / ス-パ-オキシド / zymosan. / タイロシン / ESR / スーパーオキシド / ヒドロキシルラジカル / マクロファージ / 食細胞 / 定着 / 侵入性 / 毒素 / 生体機能 / バイオダイナミクス因子 / 生体防御の方向付け / 生体防御機構の再構築 / 免疫系の分化機序 / 食細胞機能 / 生体防御機構の系統発生 / 異物識別機構 / 非TPAタイプ発癌プロモーター / 慢性肉芽腫症 / 活性酸素種 / NADPHオキシダーゼ系 / Tリンパ球 / CGD-mouse / processing / 抗原提示 / 慢性肉芽腫症(CGD) / 倫理審査 / 遺伝子治療・臨床プロトコール / 単一遺伝子病 / 白血病 / 悪性リンパ腫 / 固形がん / 難治性疾患 / 遺伝子治療 / ス-パ-オキシドアニオン / チトクロムPー450 / オキシゲナ-ゼ / チトクロムcオキシダ-ゼ / 酸素毒性 / 酸素の活性化 / 酸素 Less
  • Research Projects

    (25 results)
  • Co-Researchers

    (48 People)
  •  ヒトBリンパ球の活性酸素産生の意義

    • Principal Investigator
      小林 園子
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  新しい好酸球走化性因子「エカレクチン」の遺伝子クローニングとその性質の解析Principal Investigator

    • Principal Investigator
      金ケ崎 士朗
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  悪性Tリンパ腫に発現したスーパーオキシド産生系の解析Principal Investigator

    • Principal Investigator
      金ヶさき 士朗
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Newly developed retrovirus for CGD gene-therapy : Cooperarive study of its effectivenessPrincipal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  A novel gene therapeutic strategy for chronic granulomatous disease.Principal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  悪性リンパ腫におけるスーパーオキシド産生系の発現の解析Principal Investigator

    • Principal Investigator
      金ケ崎 士朗
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analysis of molecular mechanism of inherited phagocyte disorders.Principal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  The Superoxide-generating System and its Function in Human B Lymphocytes

    • Principal Investigator
      KOBAYASHI Sonoko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  悪性リンパ腫におけるスーパーオキシド産生系の解析とその発現の意義Principal Investigator

    • Principal Investigator
      金ヶ崎 士朗
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  難治性疾患に対する遺伝子治療の臨床への展開

    • Principal Investigator
      ASANO Shigetaka
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      内科学一般
    • Research Institution
      The University of Tokyo
  •  慢性内芽腫症の基礎的研究 b型シトクロムおよび細胞質因子欠損の遺伝生化学的解析Principal Investigator

    • Principal Investigator
      金ヶ崎 士朗
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Activation mechanism of superoxide generating system in neutrophils upon bacterial infection.Principal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  Restoration of superoxide generating ability to the cells derived from chronic granulomatous disease by protein or gene transfer.Principal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      The University of Tokyo
  •  慢性肉芽腫症の基礎的研究b型シトクローム大鎖欠損の遺伝生化学的解析Principal Investigator

    • Principal Investigator
      金ヶ崎 士朗
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  慢性肉芽腫症の基礎的研究 b型シトクロ-ム大鎖欠損の遺伝生化学的解析Principal Investigator

    • Principal Investigator
      金ケ崎 士朗
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  生体系における酸素活性化とその制御の分子機構

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Keio University
  •  Role of active oxygen generated by neutrophils during bacterial infectionPrincipal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Active oxygen species produced during phagocytosis.

    • Principal Investigator
      UENO Ikuko
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Mechanism of Active Oxygen Generation in Neutrophils and Its Role in Defense Against Bacterial InfectionPrincipal Investigator

    • Principal Investigator
      KANEGASAKI Shiro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The Institute of Medical Science, the University of Tokyo
  •  Fate of endotoxin in the body: It's modification and decomposition in various types of cells.

    • Principal Investigator
      UENO Ikuko
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  微生物由来バイオダイナミクス因子による生体機能の障害と制御

    • Principal Investigator
      三輪谷 俊夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      細菌学
    • Research Institution
      Osaka University
  •  日本人におけるミエロペルオキシダーゼの遺伝的欠損と易感染性の関連

    • Principal Investigator
      石村 巽
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Keio University
  •  生体防御機構の基礎的研究

    • Principal Investigator
      野本 亀久雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  食細胞の活性産生酸素機構の解析Principal Investigator

    • Principal Investigator
      金ヶ崎 士朗 (金ケ崎 士朗)
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      細菌学
    • Research Institution
      The University of Tokyo
  •  Mechanism of Differentiation and Proliferation of Granulocytes and Macrophages

    • Principal Investigator
      NAGATA Shigekazu
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Institute of Medical Science, University of Tokyo,
  • 1.  KOBAYASHI Sonoko (00013764)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  NUNOI Hiroyuki (50218260)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  IMAJOH-OHMI Shinobu (20160046)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  UENO Ikuko (60012738)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  ONO Yasuo (10177272)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  KURIBAYASHI Futoshi (60251443)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  ASANO Shigetaka (50134614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  石村 巽 (40025599)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  松本 良二 (20272495)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  飯塚 哲太郎 (30029475)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  NAKAMURA Michio (30091276)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  KOMIYAMA Jun (50020798)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KITAGAWA Seiichi (50133278)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SENDO Fujiro (80091833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOBAYASHI Kunihiko (60091451)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NAGATA Shigekazu (70114428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KAZIRO Yoshito (90012690)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  森島 績 (50026093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  北川 禎三 (40029955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  西野 武士 (40094312)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  折井 豊 (60028149)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  島田 隆 (20125074)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  新津 洋司郎 (10045502)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  斉藤 泉 (70158913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  新井 賢一 (00012782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  田中 葉子 (30138052)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  加野 象次郎 (80051671)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  野本 亀久雄 (50037355)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  村松 繁 (30025291)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  片桐 千明 (90000827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  高久 史磨 (40048955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  光山 正雄 (10117260)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  三輪谷 俊夫 (60029759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  加藤 巌 (40012702)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  吉川 弘之介 (80012714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  竹田 美文 (30029772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  今野 多助 (00004846)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  竹重 公一朗 (10037450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  小林 陽之助 (50034062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  安田 立二 (30092357)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  棚元 憲一 (60107430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  MALY Friedrich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  DINAUER Mary C.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  MALECH Harry
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  荒井 正
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  FRIERICH Ern
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  DINAUER Marr
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  島津 光伸
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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