YAJIMA Toshihiko 矢嶋俊彦

… Alternative Names

矢島俊彦ヤジマトシヒコ

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Researcher Number	10018749
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1995 – 2007: 北海道医療大学, 歯学部, 教授 1993: , SCHOOL OF DENTISTRY, DEPARTMENT OF ORAL ANATOMY, PROFESSOR, 歯学部, 教授 1992: 東日本学園大学, 歯学部, 教授 1989 – 1990: 東日本学園大学, 歯学部, 教授 1986 – 1987: Higashi-Nippon-Gakuin University, School of Dentistry, Professor, 歯学部, 教授
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry / 畜産学(含草地学) / Conservative dentistry Except Principal Investigator 矯正・小児・社会系歯学 / 補綴理工系歯学 / 応用薬理学・医療系薬学 / Periodontal dentistry / Surgical dentistry / Morphological basic dentistry
Keywords	Principal Investigator 歯周組織 / MAGP-1 / コラーゲン貧食 / 骨改造現象 / 酸性ホスファターゼ / 線維芽細胞 / MMP-2 / 歯槽骨 / 骨芽細胞 / コラゲン吸収・分解 … More / コラゲン貧食 / コラゲン貪食 / Periodontium / Collagen phagocytosis / PGE / 弾性系線維 / エラスチン / フィブリリン / TIMP-2 / フィブリン / elastic system fibers / elastin / fibrillin / fibroblasts / periodontal tissues / カテプシンB / 歯周病 / 歯周病原菌 / 定着機序 / 定着阻害 / Bacteroides gingivalis / Bacteroides intermedius / LPS / ノイラミニダーゼ / 疎水性 / コラゲン線維 / 酸性フォスファターゼ活性 / セメント芽細胞 / マラッセ上皮遺残 / 酸性ホスファタ-ゼ / アルカリホスファタ-ゼ / 歯周組織改造機構 / コラゲン改造機構 / Cementoblast / Epithelial rests of Malassez / Collagen degradation / Acid phosphatase / Alkaline phosphatase / Remodeling of periodontium / 骨芽細胞(骨芽細胞様細胞) / コラゲン貪食小体 / 骨吸収窩 / 破骨細胞 / コラゲン貧食小体 / 骨吸収 / 骨芽細胞・前骨芽細胞 / ストローマ細胞 / カテプシンD / Bone remodeling / Osteoblast / Collagen phagolysosome / Howship's lacunae / Osteoclast / 加齢変化 / 歯周組織線維芽細胞 / 細胞サイクル / 細胞増殖能 / インターロイキン / コラーゲン産生・分解 / c-fos発現 / IL-6産生 / コラーゲン産生 / 歯周靭帯細胞 / 歯肉線維芽細胞 / アルカリ性ホスファターゼ / PGE_2産生 / カテプシンB,L / Age changes / Periodontal fibroblasts / Cell cycle / Proliferative capacity / Interleukin production / Collagen secretion and degradation / コラーゲン貪食 / 骨細胞 / 酒石酸耐性酸性ホスファターゼ / 細胞内コラーゲン消化 / カテプシン / alveolar bone / osteoblast / collagen phagocytosis / osteocytes / acid phosphatase / tartrate-resistant acid phosphatase / periodontium / bone remodeling / フブリン / エラウニン線維 / MAGP-2 / オキシタラン線維 / fibulin / elaunin fibers / 微細線維 / フィブリリン-2 / MMP inhibitor / フィビユリン-5 / microfibrils … More Except Principal Investigator 高齢者 / アポトーシス / 細胞外マトリックス / 顎関節 / RT-PCR / Temporomandibular joint / ALPase / 緩圧機構 / 弾性材料 / 衝撃波 / 周波数分析 / インプラント義歯 / 咀嚼機能 / 咬合機能 / ペグボ-ド / 痴呆 / 老化ラット / 相対的骨濃度 / 関節頭 / 手指巧緻性 / 舌運動 / 超音波診断装置 / Motion-modulation / Masticatory Function / Elderly Person / Dementia / Finger Skill / Tongue Movement / Ultrasound Diagnostic System / Temporomandibular Joint / Bone Density / 嘔吐 / 5-HT / 5-HT受容体 / エンテロクロマフィン細胞 / セロトニン / 脱顆粒 / 制がん剤 / 迷走神経 / Drug-induced emesis / Serotonin / 5-HT3-receptor / Enterochromaffin cell / Ferret / サイトカイン / 細胞接着分子 / 免役担当細胞 / 線維芽細胞 / 上皮細胞 / プロスタグランジン / 免疫担当細胞 / CYTOKINE / CELL ADHESION MOLECULE / IMMUNOCOMPETENT CELL / APOPTOSIS / EXTRACELLULAR MATRIX / FIBROBLAST / EPITHELIAL CELL / PROSTAGLANDIN / 歯の移動 / 骨細胞 / 細胞死 / ネクローシス / メカニカル・ストレス / メカニカルストレス / tooth movement / osteocyte / cell death / Apoptosis / necrosis / プワテオグリカン / コラーゲン / 軟食摂取 / Western-Blotting / 免疫組織化学 / プロテオグリカン / Western Blotting / 顎関節円板 / バーシカン / 成長変化 / ノーザン・ハイブリダイゼーション / PCR / cDNA / Extracellular matrix / Proteoglycan / Colllagen / Food consistency / Western blotting / Immunohistochemistry / 過剰開口 / 滑膜炎 / ラット / 早期反応 / 光学顕微鏡的観察 / 電子顕微鏡的観察 / Hypermobility / Synovitis / Rat / Early response / Light microscopy / Electronmicroscopy / 歯周組織 / 老化 / ヒスタミン / 歯の動揺度 / Periodontal tissue / Aging / Histamine Less

Elastic System Fibers Formation and Degradation in the Periodontal TissuesPrincipal Investigator
- Principal Investigator
  
  YAJIMA Toshihiko
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Health Sciences University of Hokkaido
Elastic System Fibers Formation and Degradation in the Periodontal TissuesPrincipal Investigator
- Principal Investigator
  
  YAJIMA Toshihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Health Sciences University of Hokkaido
Effects of food consistency on expression of extracellular matrices in the temporo-mandibular joints
- Principal Investigator
  
  MIZOGUCHI Itaru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Health Sicence University of Hokkaido
A study on the pathohistology of the synovitis and the mechanism of the synovial adhesion
- Principal Investigator
  
  MUTO Toshitaka
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Health Sciences University of Hokkaido
Collagen Degradation and Remodeling at the Alveolar Bone-Ligament Interface.Principal Investigator
- Principal Investigator
  
  YAJIMA Toshihiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Health Science University of Hokkaido
Cell adhesion molecules and cytokines in periodontal disease
- Principal Investigator
  
  TANAKA Akio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
Reaction of intercellular network of osteocytes in alveolar bone during experimental tooth movement
- Principal Investigator
  
  MIZOGUCHI Itaru
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Health Sciences University of Hokkaido
歯槽骨における骨芽細胞のコラーゲン消化・吸収機構の解明Principal Investigator
- Principal Investigator
  
  矢嶋俊彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Health Sciences University of Hokkaido
Synthetic Studies of Age Changes on PriodontiumPrincipal Investigator
- Principal Investigator
  
  YAJIMA Toshihiko
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Conservative dentistry
- Research Institution
  Health Sciences University of Hokkaido
Studies on mechanism of exocytosis of serotonin from enterochromaffin cell
- Principal Investigator
  
  MINAMI Masaru
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Department of Pharmacology, Faculty of Pharmaceutical Sciences, Health Sciences
高齢無歯顎者のインプラント義歯に関する研究
- Principal Investigator
  
  HIRAI Toshihiro
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Institution
  Health Sciences University of Hokkaido
COLLAGEN DEGRADATION MECHANISM IN BONE REMODELINGPrincipal Investigator
- Principal Investigator
  
  YAJIMA Toshihiko
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  畜産学(含草地学)
- Research Institution
  Health Sciences University of Hokkaido
Masticatory Function and Physical/ Mental Activities
- Principal Investigator
  
  HIRAI Toshihiro
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  補綴理工系歯学
- Research Institution
  HigashiーNipponーGakuen University
Collagen Degradation and Remodeling of the PeriodontiumPrincipal Investigator
- Principal Investigator
  
  YAJIMA Toshihiko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Higashi-Nippon-Gakuen University
歯周病原菌の定着機序の解析とその定着阻害Principal Investigator
- Principal Investigator
  
  奥田克爾, 矢嶋俊彦
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo Dental College
  Health Sciences University of Hokkaido
A basic study on aging of periodontal tissues
- Principal Investigator
  
  MIAKE Kiyoshi
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo Dental College

All 2007 2005 2004

All Journal Article Presentation

[Journal Article] Elastic system fibers -Molecular properties of tropoelastin and microfibrils-2007
- Author(s)
  Tsuruga E, Yajima T
- Journal Title
  
  Dentistry in Japan 43
  
  Pages: 119-122
- NAID
  10021953561
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Elastic system fibers-Molecular properties of tropoelastin and microfibrils2007
- Author(s)
  Turuga E, Yajima T
- Journal Title
  
  Dentistry in Japan 43
  
  Pages: 119-122
- NAID
  10021953561
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Fibrillin-2 degradation by matrix metalloproteinase-2 in periodontium2007
- Author(s)
  Tsuruga E, Irie K, Yajima T
- Journal Title
  
  J Dent Res 86
  
  Pages: 352-357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Fibrillin-2 degradation by matrix metalloproteinase-2 in periodontium2007
- Author(s)
  Tsuruga, E., Irie, K., Yajima, T
- Journal Title
  
  Journal of Dental Research 86
  
  Pages: 352-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Elastic system fibers-Molecular properties of tropoelastin and microfibrils-2007
- Author(s)
  Tsuruga, E., Yajima, T
- Journal Title
  
  Dentistry in Japan 43
  
  Pages: 119-122
- NAID
  10021953561
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Fibrillhin-2 degradation by matrix metalloproteinase-2 in periodontium2007
- Author(s)
  Turuga E, Irie K, Yajima T
- Journal Title
  
  Journal of Dental Research 86
  
  Pages: 352-356
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Microfibril-associated glycoprotein-1 and fibrillin-2 are associated with tropoelastin deposition in vitro2005
- Author(s)
  Tsuruga, E., Yajima, T., Irie, K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 37
  
  Pages: 120-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Microfibril-assosiated glycoprotein-1 and fibrillin-2 are associated with tropoelastin deposition in vitro.2005
- Author(s)
  Tsuruga E, Yajima T, Irie K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 37
  
  Pages: 120-129
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] Microfibril-associated glycoprotein-1 and fibrillin-2 are associated with tropoelastin deposition in vitro2005
- Author(s)
  Turuga E, Yajima T, Irie E
- Journal Title
  
  Journal of Biochemistry & Cell Biology 37
  
  Pages: 120-129
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Microfibril-associated glycoprotein-1 and fibrillin-2 are associated with tropoelastin deposition in vitro.2005
- Author(s)
  Tsuruga E, Yajima T, Irie K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 37
  
  Pages: 120-129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] Microfibril-associated glycoprotein-1 and fibrillin-2 are associated with tropoelastin deposition in vitro.2005
- Author(s)
  Tsuruga E, Yajima T, Irie K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 37
  
  Pages: 120-129
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Impaired alveolization in mice deficient in membrane-type matrix metalloproteinase 1 ( MT1-MMP).2005
- Author(s)
  Irie K, Komori K, Seiki M, Tsuruga E, Sakakura Y, Kaku T, Yajima T
- Journal Title
  
  Medical Molecular Morphology 38
  
  Pages: 43-46
- NAID
  10018374513
- Data Source
  KAKENHI-PROJECT-17591920
[Journal Article] Microfibril-assosiated glycoprotein-1 and fibrillin-2 areassociated with tropoelastin deposition in vitro.2005
- Author(s)
  Tsuruga E, Yajima T, Irie K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 37
  
  Pages: 120-129
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] 歯周組織の弾性系線維2004
- Author(s)
  矢嶋俊彦, 敦賀英知, 入江一元
- Journal Title
  
  日本歯周病学会会誌 46巻3号
  
  Pages: 175-184
- NAID
  10013565087
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] Induction of fibulin-5 gene is regulated by tropoelastin gene, and correlated with tropoelastin accumulation in vitro.2004
- Author(s)
  Tsuruga E, Yajima T, Irie K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 36
  
  Pages: 395-400
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] Elastic system fibers in the periodontal tissues.2004
- Author(s)
  Yajima, T, Tsuruga, E, Irie K
- Journal Title
  
  Journal of the Japanese Scociety of Periodontology 46
  
  Pages: 175-184
- NAID
  10013565087
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] Induction of fiburillin-5 gene is regulated by tropoelastin gene, and correlated with tropoelastin accumulation in vitro.2004
- Author(s)
  Tsuruga E, Yajima T, Irie K
- Journal Title
  
  International Journal of Biochemistry & Cell Biology 36
  
  Pages: 395-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591942
[Journal Article] 歯周組織の弾性系線維2004
- Author(s)
  矢嶋俊彦, 敦賀英知, 入江一元
- Journal Title
  
  日本歯周病学会会誌 46巻号
  
  Pages: 175-184
- NAID
  10013565087
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591942
[Presentation] Fubulin-5 are associated with microfibril organizing2007
- Author(s)
  Tsuruga, E., Yajima, T., Sawa, S
- Organizer
  Japanese Association for Oral Biology, 49th Annual Meeting
- Place of Presentation
  Sapporo
- Year and Date
  2007-08-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591920
[Presentation] Fibulin-5は微細線維上に存在し、微細線維を形成する2007
- Author(s)
  敦賀英知、矢嶋俊彦、沢禎彦
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌市
- Year and Date
  2007-08-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591920

1. EICHI Tsuruga (30295901)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. IRIE Kazuharu (70223352)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. KATOH Hiroshi (60001020)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. HIRAI Toshihiro (80014273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IKEDA Yasuhiro (10193195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KOSHINO Hisashi (90186669)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIZOGUCHI Itaru (20200032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SASANO Yasuyuki (30196191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. KOHN Kunihiko (20186844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANAKA Osamu (40146866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MINAMI Masaru (00142711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ENDO Toru (80194041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HIRAFUJI Masahiko (20142987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIMURA Fusanori (80208222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ABIKO Yoshimitsu (70050086)

# of Collaborated Projects: 1 results

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16. KOWASHI Yuhsuke (60014338)

# of Collaborated Projects: 1 results

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17. KAMEYAMA Yoichirou (70113066)

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# of Collaborated Products: 0 results
18. TANAKA Akio (10121823)

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19. OTSUKA Kichibei (50059995)

# of Collaborated Projects: 1 results

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20. SAITO Kazuko (30008247)

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# of Collaborated Products: 0 results
21. MAITA Eikichi (80108547)

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# of Collaborated Products: 0 results
22. KOGA Toshihiko (10037541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAKAKURA Yasunori (60128915)

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24. KAGAYAMA Manabu (60004610)

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25. TAKEUCHI Makoto (00143595)

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26. TAKUMA Taishin (40095336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MUTO Toshitaka (00143298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KAKU Tohru (60133253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. KAWAKAMI Johji (20244858)

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30. MIAKE Kiyoshi (30085691)

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31. SAITO Shigeru (80084713)

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32. UYENO Kazuyuki (00048307)

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33. HORIUCHI Hiroshi (00013962)

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34. NAKASHIZUKA Tadashi (00064767)

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35. 小西洋次 (00195760)

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36. 石島勉 (60211041)

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# of Collaborated Products: 0 results
37. 奥田克爾 (40085741)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 小野美千代 (60167327)

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39. 加藤哲男 (00159253)

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40. 内藤祐子 (00147258)

# of Collaborated Projects: 1 results

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41. 高添一郎 (80085696)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 高田隆 (10154783)

# of Collaborated Projects: 1 results

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43. 村上伸也 (70239490)

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44. 山崎和久 (00182478)

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45. 林一夫 (20316269)

# of Collaborated Projects: 1 results

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46. 荒川俊哉 (40306254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. KASUNOKI Shinichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAJIMA Toshihiko 矢嶋 俊彦

矢島 俊彦 ヤジマ トシヒコ

Research Projects

Research Products

Co-Researchers

Elastic System Fibers Formation and Degradation in the Periodontal TissuesPrincipal Investigator

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Elastic System Fibers Formation and Degradation in the Periodontal TissuesPrincipal Investigator

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Collagen Degradation and Remodeling at the Alveolar Bone-Ligament Interface.Principal Investigator

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歯槽骨における骨芽細胞のコラーゲン消化・吸収機構の解明Principal Investigator

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Synthetic Studies of Age Changes on PriodontiumPrincipal Investigator

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COLLAGEN DEGRADATION MECHANISM IN BONE REMODELINGPrincipal Investigator

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Collagen Degradation and Remodeling of the PeriodontiumPrincipal Investigator

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YAJIMA Toshihiko 矢嶋俊彦

矢島俊彦ヤジマトシヒコ