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MISU Yoshimi  三須 良實

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… Alternative Names

三須 良実  ミス ヨシミ

MISY Yoshimi  三須 良実

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Researcher Number 10025687
External Links
Affiliation (based on the past Project Information) *help 1994 – 1998: 横浜市立大学, 医学部, 教授
1989 – 1992: 横浜市立大学, 医学部, 教授
1987: Yokohama City University . Professor, 医学部, 教授
1986: 横浜市大, 医学部, 教授
Review Section/Research Field
Principal Investigator
General pharmacology / 応用薬理学・医療系薬学
Except Principal Investigator
Laboratory animal science
Keywords
Principal Investigator
ドーパ / 4血管閉塞脳虚血 / 線条体微量透析 / 神経細胞死因子ドーパ / 線条体 / 孤束核-尾側腹外側延髄ドーパ性投射 / L-ドーパ / 競合的ドーパ拮抗薬 / Microdialysis / DOPA … More / グルタミン酸遊離 / ドーパ脱炭酸酵素阻害薬神経細胞死増悪 / 脳虚血上流因子内因性ドーパ / 視床下部 / 神経活性物質 / シナプス前β-アドレナリン受容体 / ドパミン / Presynaptic inhibitory dopamine receptors / Presynaptic facilitatory <beta>-adrenoceptors / Neuroactive substance / Regulatory actions on dopamine and norepinephrine release / DOPA release / シナプス前ドパミン受容体 / チロシン水酸化酵素 / TTX感受性 / 【Ca^(2+)】依存性 / 神経伝達物質 / ドパミン・ノルエピネフリン遊離制御作用 / シナプス前抑制性ドパミン受容体 / シナプス前促進性β受容体 / ドパミン遊離制御作用 / ドーパ遊離 / hippocampus / transporter / neuronal cell death / ischemia / striatum / baroreceptor reflex / nucleus tractus solitarii / L-DOPA / 脳虚血グルタミン酸誘発上流因子内因性ドーパ / ドーパトランスポーター / 高電位活性化Ca^<2+>チャネル電流促進 / 孤束核単離細胞 / 圧受容器情報伝達物質ドーパ / 海馬 / トランスポーター / 神経細胞死 / 虚血 / 圧受容体反射 / 弧束核 / Ca^<2+> influx measured with fura-2 / Causal factor for delayd neuronal cell death / DOPA-induced glutamate release / High voltage-activated Ca^<2+> channel current / Competitive DOPA antagonists / Altered DOPA ergic transmission and maintenance of hypertension / DOPA-GABA-interactions / Transmitter of baroreflex information pathway / グルタミン酸遊離増大 / アセチルコリン遊離抑制 / GTPase活性抑制 / シナプス後D_2受容体伝達効率増強 / 圧受容器反射第一次求心性神経伝達物質 / カルシウム流入増加 / グルタミン酸遊離増大感作作用 / パーキンソン病ラットモデル線条体 / ドーパ性単シナプス性圧受容反射経路 / 高血圧自然発症ラット / 孤束核ドーパ・GABA系相互作用 / ドーパ拮抗薬感受性-高電位活性化Ca^<2+>チャネル電流増大 / 線条体グルタミン酸遊離作用 / 孤束核単離神経パッチクランプ / ドーパ受容体クローニング / DOPA cyclopentyl ester / 強力・安定なドーパ競合的拮抗薬開発 / 腹外側延髄微量透析ドーパ遊離 / 孤束核-腹外側延髄ドーパ性圧受容情報伝達 / fura-2を用いて測定したCa^<2+>流入 / 遅発性神経細胞死原因因子 / ドーパ誘起グルタミン酸遊離 / 高電位活性化Ca^<2+>チャネル電流 / ドーパ性伝達変動と高血圧維持 / ドーパ-GABA-相互作用 / 圧反射情報路伝達物質 / Agonist for "DOPAergic receptors" / Competitive DOPA antagonist / Microinjection into NTS / Basal DOPA release / Basal glutamate release / Parkinson's model rat striata / 内因性ドーパ自発性遊離 / アフリカツメガエル卵母細胞 / パーキンソン病モデル / 内因性アセチルコリン遊離 / L-ドーパメチルエステル誘導体 / L-ドーパメチルエステル / 弧束核微量注入 / ドーパ作動薬 / 孤束核微量注入 / ドーパ基礎遊離 / グルタミン酸基礎遊離 / 微量透析 / パーキンソン病モデルラット線条体 / D_2-potentiation / Quinpirole / Nicotine / DOPA decarboxylase / Locomotor of rat / Dopamine / 自発運動 / αーメチルパラタイロシン / アセチルコリン受容体 / 伝達物質様遊離 / 自発性遊離 / 脳微量透析法 / ド-パ / ドーパ脱炭素酵素 / D_2-ポテンシエーション / クインピロール / ニコチン / ドーパ脱炭酸酵素 / ラット自発運動 / 脳微量透析 / 新規競合的拮抗薬DOPA cyclohxyl ester同保護 / 胎仔線条体神経細胞培養系 / 新規競合的拮抗薬DOPA cylohexyl ester 神経細胞死保護 / 胎仔線条体神経細胞培養 / ノルアドレナリン / Lースレオドプス / Lード-パメチルエステル / Lード-パ / C57Black mouse / 遊離 / パ-キンソン病 / MPTP / L-ド-パ … More
Except Principal Investigator
正常血圧Wistar Kyoto rat / 脳卒中易発症ラット(SHRSP) / 自然発症ラット(SHR) Less
  • Research Projects

    (10 results)
  • Co-Researchers

    (14 People)
  •  ドーパはグルタミン酸遊離-神経細胞死の上流因子か? ドーパ新競合的拮抗薬の保護作用Principal Investigator

    • Principal Investigator
      三須 良實
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Yokohama City University
  •  L-DOPA Plays a role as a neurotransmitter regulating blood pressure in the lower brain stem, and endogenously evoked L-DOPA is a casual factor for glutamate release and resultant delayed neuronal cell death by transient ischemia in ratsPrincipal Investigator

    • Principal Investigator
      GOSHIMA Yoshio, 三須 良實
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Yokohama City University
  •  ドーパは神経細胞死の要因か?-線条体培養系,前脳虚血時の役割と新規拮抗薬防御能研索Principal Investigator

    • Principal Investigator
      三須 良實
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Yokohama City University
  •  Studies on DOPA as a Transmitter, searching for its selective binding site, intracellular signal transduction mechanism and receptor cDNA cloningPrincipal Investigator

    • Principal Investigator
      MISU Yoshimi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General pharmacology
    • Research Institution
      Yokohama City University
  •  高血圧・脳卒中モデルとその対照系統の遺伝的標準化に関する研究

    • Principal Investigator
      家森 幸男
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kyoto University
  •  ESTABLISHMENT OF "L-DOPAERGIC RECEPTOR" EXPRESSION SYSTEMS IN PARKINSON'S DISEASE MODEL RATS AND DEVELOPMENT OF L-DOPA-RELATED THERAPEUTIC DRUGS.Principal Investigator

    • Principal Investigator
      MISU Yoshimi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      YOKOHAMA CITY UNIVERSITY SCHOOL OF MEDICINE,YOKOHAMA 236, JAPAN.
  •  Is DOPA an neurotransmitter?Principal Investigator

    • Principal Investigator
      MISU Yoshimi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Yokohama City University
  •  ド-パは神経伝達物質たりうるか?ーその競合的拮抗薬並びに高親和性結合部位の探究Principal Investigator

    • Principal Investigator
      三須 良実
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Yokohama City University
  •  マウスパ-キンソン病モデル線条体と同生体位におけるド-パのドパミン遊離調節機構Principal Investigator

    • Principal Investigator
      三須 良実
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Yokohama City University
  •  Transmitter-like release of endogenous DOPA and regulatory actions of L-DOPA on the release of dopamine via presynaptic receptors in rat striatal and hypothalamic slices.Principal Investigator

    • Principal Investigator
      MISY Yoshimi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Yokohama City University
  • 1.  GOSHIMA Yoshio (00153750)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 2.  MIYAMAE Takeaki (00239435)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  FURUKAWA Nobuya (90285114)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SASAKI Yukio (10295511)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  UEDA Hiroshi (00145674)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  NAKAMURA S. (20207880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  FUJI Kaoru (20027056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  FUKUSHIMA Nobuyuki (10254161)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  家森 幸男 (80025600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  西尾 一郎 (40089165)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  猿田 享男 (70051571)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  黒川 清 (30167390)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  荻原 俊男 (60107042)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOJIMA Atsuyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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