KOGA Toshihiko 古賀敏比古

Researcher Number	10037541
External Links
Affiliation (based on the past Project Information) *help	2001: 九大, 歯学研究科(研究院), 教授 2000: KYUSHU UNIVERSITY FACULTY OF DENTAL SCIENCE, PROFESSOR, 大学院・歯学研究院, 教授 2000: 九州大学, 歯学研究院, 教授 1993 – 1999: 九州大学, 歯学部, 教授 1992: NIH, Dept. of Oral Science, Director, 口腔科学部, 部長 … More 1988 – 1991: National Institute of Health, Dept of Dental Research, 歯科衛生部, 部長 1987: National Institute of Health, Dept of Dental Research, 歯学衛生部, 部長 1986: 予研, その他, 研究員 1986: 国立予防衛生研究所, 歯科衛生部, 室長 Less
Review Section/Research Field	Principal Investigator 矯正・小児・社会系歯学 / 小児・社会系歯学 Except Principal Investigator 小児・社会系歯学 / Functional basic dentistry / Periodontal dentistry
Keywords	Principal Investigator 歯周病 / Streptococcus mutans / 歯周病細菌 / 定着因子 / 齲蝕 / 多糖抗原 / 歯周炎 / 血清型 / Streptococcus sobrinus / う蝕 … More / Monoclonal Antibody / モノクローナル抗体 / Colonization Factor / Dental Caries / Glucosyltransferase / Dental caries / 融合タンパク質 / タンパク質抗原 / リポ多糖 / IL-1 / ワクチン / 多糖 / 熱ショックタンパク質 / Vaccine / Lactic Streptococci / DNA組換え / 乳酸菌 / Serotype / Latex Agglutination Assay / Periodontal Bacteria / 細菌の同定 / ラテックス凝集試験 / モノクロ-ナル抗体 / Cariogenic bacteria / Milk / ラ細菌 / ラ蝕 / う触細菌 / う触 / う蝕細菌 / 牛乳 / Lipopolysaccharide / Carbohydrate Antigen / Periodontopathic Bacteria / Periodontitis / Periodontal Disease / 莢膜多糖 / 抗原 / Prevention of Dental Caries / Protein Antigen / Passive Immunization / Fusion Protein / 齲蝕予防 / グルカン合成酵素 / 受動免疫 / ELISA / Biotin / Periodontopathic bacteria / Diagnosis method / Polysaccharide antigen / Periodontal disease / サイトカイン / 単球 / エライサ法 / ビオチン / 診断法 / Fusion protein / Protein antigen / Adherence factor / 遺伝子 / 免疫 / 付着 / スクロース / グルコシルトランスフェラーゼ / macrophage / bone resorption / periodontitis / IL-1 inhibitor / マクロフィ-ジ / マクロファ-ジ / ILー1インヒビタ- / ILー1 / インターロイキン1インヒビター / インローロイキン1 / マクロファージ / 骨吸収 / IL-1インヒビター / 抗生物質 / 歯周病原性細菌 / メチルメルカプタン / 口腔内細菌 / 口臭 / 免疫学的予防法 / レンサ球菌 / 抗体価 / 血清型抗原 / BIAcore / DnaJ / DnaK / 慢性関節リュウマチ / 口腔細菌 … More Except Principal Investigator う蝕 / S.mutans / Ltex beads / Streptococcus mutans / Monoclonal antibodies / Dental caties / 抗原抗体反応 / 凝集反応 / 診断キット / ラテックス凝集反応 / モノクローン抗体 / Gene cloning / Dental caries / Protein antigen / mutans / S / バクテリオシン / IgAプロテアーゼ / プラスミド / DNA / S.sanguis / S, mutans / S、mutans / 付着 / 遺伝子クローニング / タンパク抗原 / PROSTAGLANDIN / EPITHELIAL CELL / FIBROBLAST / EXTRACELLULAR MATRIX / APOPTOSIS / IMMUNOCOMPETENT CELL / CELL ADHESION MOLECULE / CYTOKINE / 免疫担当細胞 / プロスタグランジン / 上皮細胞 / 線維芽細胞 / 細胞外マトリックス / アポトーシス / 免役担当細胞 / 細胞接着分子 / サイトカイン Less

Research Projects
(16 results)
Co-Researchers
(26 People)

口臭原因物質合成遺伝子の解析Principal Investigator
- Principal Investigator
  
  古賀敏比古
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kyushu University
Development of bovine milk antibody to prevent dental cariesPrincipal Investigator
- Principal Investigator
  
  SHIMAZAKI Yoshihiro, 古賀敏比古
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kyushu University
組換えレンサ球菌を用いた歯周病の免疫学的予防法の開発Principal Investigator
- Principal Investigator
  
  古賀敏比古
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kyushu University
表面プラズモン共鳴バイオセンサーを応用した歯周病の簡易診断法の開発Principal Investigator
- Principal Investigator
  
  古賀敏比古
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kyushu University
Cell adhesion molecules and cytokines in periodontal disease
- Principal Investigator
  
  TANAKA Akio
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
歯周病細菌の熱ショックタンパク質の病因論的役割に関する研究Principal Investigator
- Principal Investigator
  
  古賀敏比古
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  Kyushu University
Development of Immunological Procedure for Prevention of Periodontal Disease UsingPrincipal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  KYUSHU UNIVERSITY
Development of Immunological Procedure for Prevention of Dental Caries Using Fusion Protein of Colonization FactorsPrincipal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  KYUSHU UNIVERSITY
Development of high-sensitive periodontitis diagnosis method using biotinylated polysaccharide antigensPrincipal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  矯正・小児・社会系歯学
- Research Institution
  KYUSHU UNIVERSITY
Development of immunological method for prevention of dental caries using genetic engineeringPrincipal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  小児・社会系歯学
- Research Institution
  KYUSHU UNIVERSITY
  国立予防衛生研究所
Development of an alveolar bone resorption inhibitor that suppresses interleukin-1Principal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  小児・社会系歯学
- Research Institution
  National Institute of Health
Development of simple and rapid method using monoclonal antibodies for identification of periodontal bacteriaPrincipal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  小児・社会系歯学
- Research Institution
  National Institute of Health
Development of Anti-Dental Caries Vaccine Using Recombinant Lactic StreptococciPrincipal Investigator
- Principal Investigator
  
  KOGA Toshihiko
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  小児・社会系歯学
- Research Institution
  National Institute of Health
Nocardia属由来の抗生物質による歯周病原性細菌の抑制Principal Investigator
- Principal Investigator
  
  古賀敏比古
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  小児・社会系歯学
- Research Institution
  国立予防衛生研究所
Gene Cloning of Virulence Factors of Streptococcus mutans
- Principal Investigator
  
  HAMADA Shigeyuki
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Osaka University
Rapid Method for Identification of S. mutans from Human Clinical Specimens Using Monospecific Antibodies
- Principal Investigator
  
  HAMADA Shigeyyki
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  小児・社会系歯学
- Research Institution
  Osaka University

1. NAKANO Yoshio (80253459)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. OHO Takahiko (50160940)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. HAMADA Shigeyuki (60028777)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIBATA Yukie (30274476)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NISHIHARA Tatsuji (80192251)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAMAGUCHI Noboru (00230368)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SHIMAZAKI Yoshihiro (10291519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OKAHASHI Nobuo (40150180)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. TAKADA Hatruhiko (30135743)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 中井素行

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. AKADA Hiromasa (40072920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YU Ho (30260714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TANAKA Akio (10121823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OTSUKA Kichibei (50059995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. YAJIMA Toshihiko (10018749)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SAITO Kazuko (30008247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. MAITA Eikichi (80108547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKANO Yutaka (20243925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OKANO Kaoru (40038328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MORISAKI Ichijiro (30116115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. OGAWA Tomohiko (80160761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKAHASHI Ichiro (20206791)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 村上伸也 (70239490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 山崎和久 (00182478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 辻本雅哉 (50144499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. OHTA Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOGA Toshihiko 古賀 敏比古

Research Projects

Co-Researchers

口臭原因物質合成遺伝子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of bovine milk antibody to prevent dental cariesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

組換えレンサ球菌を用いた歯周病の免疫学的予防法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

表面プラズモン共鳴バイオセンサーを応用した歯周病の簡易診断法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell adhesion molecules and cytokines in periodontal disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

歯周病細菌の熱ショックタンパク質の病因論的役割に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Immunological Procedure for Prevention of Periodontal Disease UsingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Immunological Procedure for Prevention of Dental Caries Using Fusion Protein of Colonization FactorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of high-sensitive periodontitis diagnosis method using biotinylated polysaccharide antigensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of immunological method for prevention of dental caries using genetic engineeringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of an alveolar bone resorption inhibitor that suppresses interleukin-1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of simple and rapid method using monoclonal antibodies for identification of periodontal bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Anti-Dental Caries Vaccine Using Recombinant Lactic StreptococciPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

KOGA Toshihiko 古賀敏比古