NAKA Michiko 中充子

Researcher Number	10093139
External Links
Affiliation (based on the past Project Information) *help	2002: 三重大学, 医学部, 講師 1994 – 2002: 三重大学, 医学部, 助手 1986 – 1991: 三重大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / 物質生物化学 Except Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / Biological Sciences / 物質生物化学
Keywords	Principal Investigator S100C / S100L / Actin / アクチン / カルシウム / 平滑筋 / カルポニン / Myosin light chain kinase / protein phosphorylation / Platet … More / ミオシン軽鎖キナーゼ / Cキナーゼ / ミオシン軽鎖リン酸化酵素 / 蛋白質リン酸化反応 / 血小板 / Actin activated Mg myosin ATPase activity / calponin / Actin binding gites / Calcium / S100 family / smooth muscle / 収縮制御 / アクチン活性化ミオシンATPase / アクチン活性化MgミオシンATPase活性 / アクチン結合部位 / S100ファミリー / antiallergic drugs / Protein kinase / Chemotactic proteins / Eosinophils / Signal transduction / Differential Gene Expression / Calcium-binding Proteins / 好酸球走化性 / 好酸球定化性 / 遺伝子 / 抗アレルギー薬 / 蛋白質リン酸化酵素 / 走化性蛋白質 / 好酸球 / 情報伝達 / 異遺伝子発現 / カルシウム結合蛋白質 / Ca2+-sensitivity / PKC / Contraction / Phosphorylation / Calcium ion / Smooth muscle / Calponin / シグナル伝達 / 血管収縮 / 冠状動脈 / 繰り返し構造 / アクチン結合 / プロテインキナーゼC / 収縮 / プロティンキナーゼC / カルシウム感受性 / リン酸化反応 … More Except Principal Investigator S100C / カルシウム結合蛋白質 / 遺伝子発現 / カルシウム / ML-9 / S100L / 脳血管攣縮 / カルモデュリン / 低酸素 / 分子薬理学 / 心筋 / S100蛋白質 / カルポニン / ミオシン軽鎖キナーゼ / HSP72 / actin / gene expression / caltractin / in situ hybridization / mRNA differential display / Tumor Cell / Differential Gene Expression / Calcium-binding Proteins / 癌細胞 / 遺伝子発現変化 / PAF / Calmodulin / S100 protein / Cキナーゼ / トランスクリプトーム / cerebral vasospasm / Heme Oxygenase-1 / EFハンド / カルシウム感受性 / ラット / cDNAクローニング / S100蛋白質ファミリー / 分子生物学 / 分化制御 / アクチン / カルシウムイオン / 平滑筋 / Protein kinase C / Affinity chromatography / Thyroxine / Myosin light chain kinase / サイロキシン / Aキナーゼ / アフィニティークロマトグラフ / プロテインキナーゼ阻害剤 / Myosin Light Chain Kinase Inhibitor / Aggregation and Secretion Response of Platelets / Myosin Light Chain Kinase Vascular Smooth Muscle Contraction / Myosin Light Chain Phosphorylation / Intracellular Calcium Requlation / 血小板放出反応 / 平滑筋収縮反応 / カルシウム依存性リン酸化反応 / MLー9 / ミオシン軽鎖キナーゼ阻害剤 / 放出反応 / 血小板凝集 / 血管平滑筋収縮 / ミオシン軽鎖リン酸化反応 / 細胞内カルシウム調節機構 / Myosin Light Chain Kinase / Calpain / Calcium-dependent Protease / Protein Kinase C / Molecular Pharmacology / Intracellular Calcium-Receptine Protein / カルモデュリン依存性酵素 / パルブアルブミン / トロポニンC / カルシウムチャンネルブロッカー / カルモデュリン阻害剤 / ミオシン軽鎖リン酸化酵素 / カルパイン / カルシウム依存性プロテアーゼ / プロテインキナーゼC / 細胞内カルシウム受容蛋白質 / proteome database / pulmonary hypertension / stress protein / proteome / vascular remodeling / くも膜下出血 / クモ膜下出血 / タウリン / 低酵素 / プロテオームデータベース / 肺高血圧症 / ストレス蛋白質 / プロテオーム / 血管リモデリング / splicing / phosphodiesterase / Basedow's disease / thyroid disease / Pharmacogenomics / クローニング / スプライシング / PDE / バセドウ病 / 甲状腺疾患 / 薬理ゲノミクス / hypoxia / Mg2+-ATPase / calcium sensitization / 血管収縮 / Mg-ATPase活性 / Mg-ATPase / Actin Binding Proteins / calcium / Gene Expression / Disease / S100 Protein Family / 種々の病態 / アクチン結合タンパク質 / 病態 / S100ファミリー / Genomic Gene / Hypoxia / Ischemic Heart Disease / genomic gene / 虚血性心疾患 / breast carcinoma / human clinical pathology / gene therapy / マルチメディアデータベース / キャピラリー電気泳動 / 薬物治療遺伝子 / 病態遺伝子 / 螢光ディファレンシャル・ディスプレイ法 / 薬物治療学 / two-hybrid system / 乳癌 / ヒト疾患病態 / 遺伝子治療 / Eosinophilic Chemotactic Factor / Heart Disease / Proplanolol / 好酸球走化性因子 / 心疾患 / プロプラノロール / Signal transduction / Ca^<2+>-binding protein / Chemotaxis / Eosinophil / Leucocyte / 白血球活性化因子 / 細胞内情報伝達 / 好酸球 / 走化性 / 白血球 / Beart / Kidney / Cytoskeleton / Inhibitor / Calcium binding protein / Calcium ion / S100蛋白質ファミリ- / アフィニティ-クロマトグラフィ- / アフィニティークロマドグラフィー / カルシウム情報伝達 / 心臓 / 腎臓 / 細胞骨格 / 阻害薬 / 発癌プロモーター / 細胞増殖 / チロシンキナーゼ / 遺伝子クラスター / DNAマイクロアレイ / heat shock protein 27 / heat shock protein 72 / antisense oligodeoxynucleotide / rat / basilar artery / hemin / cGMP / CO / 脳虚血 / DNAチップ / ゲノム創薬科学 / 脳血管障害 / 脳底動脈 / 創薬ターゲット / 治療関連遺伝子 / 疾患関連遺伝子 / トランスクリプトーム解析 / 薬理ゲノム科学 / ハイポキシアレスポンスエレメント / カルシウム結合蛋白 / 悪性腫瘍 / in silico cDNAクローニング / ESTデータベース / カルシウムセンシタイザー / 収縮機構 / 血管平滑筋 / 活性ペプチド / リン酸化部位 / プロテインキナーゼ / ラフト / 転写因子 / トロポミオシン / 蛋白質リン酸化反応 / プロテインキナ-ゼC / cDNAクロ-ニング / Cキナ-ゼ / cAMP依存性蛋白質リン酸化酵素 / cAMP / メラノーマ / がん細胞 / Sー100 Less

脳血管障害におけるゲノム創薬ターゲット探索法の開発
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
トランスクリプトーム解析とファルマインフォマティクスの統合ゲノム薬理学
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Pharmacoproteomic mechanisms in stress protein expression induction
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
脳血管障害におけるゲノム創薬科学解析法の開発
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
脳血管攣縮における一酸化炭素(CO)/cGMPシグナリングの治療的役割
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Pharmacogenomics of thyroid disease in molecular target discovery
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
トランスクリプトーム解析によるゲノム創薬科学
- Principal Investigator
  
  田中利男
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
Molecular cell pharmacology of novel smooth muscle regulation moleculePrincipal Investigator
- Principal Investigator
  
  NAKA Michiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
シグナル伝達の細胞内局在に関する薬理ゲノム科学的解析
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
新しいカルシウムシグナリングの分子機構に関する薬理学的研究
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
Genome pharmacology on novel calcium signaling in diseases
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Clinical Therapeutic Research of Calcium Sensitization
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
新しいプロティンキナーゼ基質分子のシグナル伝達機構に関する研究
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Molecular cell pharmacology on calcium signaling in diseases
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Molecular cell pharmacology of gene expression in eosinophils by antiallergic drugs diseasesPrincipal Investigator
- Principal Investigator
  
  NAKA Michiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
Molecular cell pharmacology on Novel calcium signaling
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Mie University
Novel Molecular Pharmacological Strategy in Clinical Therapeutic Research
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
心筋細胞の分化機構に関する分子生物学的研究
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Novel all signoling in vascular smooth musclePrincipal Investigator
- Principal Investigator
  
  NAKA Michiko
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Mie University
心筋細胞の分化制御機構に関する分子生物学的研究
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Molecular Pharmacology of Leucocyte Activation
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University
新しいS100蛋白質ファミリ-の癌細胞における発現とその調節機構
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Mie University
カルポニンを介する平滑筋収縮の調節機構
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Molecular Pharmacology of Calcium Signal Transduction
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University(School of Medicine)
がん細胞における新しいカルシウム結合蛋白質の検索とその機能発現機構の解析
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Mie University
CAMP依存性蛋白質リン酸化反応によるカルシウム情報伝達の制御機構
- Principal Investigator
  
  田中利男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Molecular pharmacological approarches of intracellular calcium regulatory mechanisms
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagoya University School of Medicine
Molcular control of platelets function by protein kinasesPrincipal Investigator
- Principal Investigator
  
  NAKA Michiko
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Mie University
Development of analytical method of molecular function in protein kinases by using newly synthesized protein kinase inhibitor - affinity chromatography
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  物質生物化学
- Research Institution
  Nagoya University School of Medicine
  Mie University
発癌機構におけるCキナーゼ及びチロシンキナーゼによる蛋白質リン酸化反応の意義
- Principal Investigator
  
  HIDAKA Hiroyoshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Mie University
Molecular Pharmacology of Intracellular Calcium-Receptive Protein Signaling
- Principal Investigator
  
  TANAKA Toshio
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Mie University

All 2004 2003 2002

All Journal Article Book

[Book] ゲノム研究実験ハンドブック(辻本豪三、田中利男編)2004
- Author(s)
  田中利男
- Total Pages
  6
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage.2004
- Author(s)
  Hirofumi Nikaido, Hiroshi Tsunoda, Yuhei Nishimura, Takaaki Kirino, Toshio Tanaka
- Journal Title
  
  Circulation 110(13)
  
  Pages: 1839-1846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Changes in Cyclic Nucleotide Phosphodiesterase Activity and Calmodul in Concentration in Heart Muscle of Cardiomyopathic Hamsters.2004
- Author(s)
  Rumi Masunaga, Akio Nagasaka, Yoshikuni Sawai, Nobuki Hayakawa, Akira Nakai, Keiko Hotta, Yasuchika Kato, Hitoshi Hishida, Hisahide Takahashi, Michiko Naka, Yasuhito Shimada, Toshio Tanaka, Hiroyoshi Hidaka, Mitsuyasu Itoh
- Journal Title
  
  J Mol Cell Cardiol. 37(3)
  
  Pages: 767-774
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Target validation in hypoxia-induced vascular remodeling using transcriptome/metabolome analysis.2003
- Author(s)
  H.Amano, K Maruyama, Michiko Naka, T Tanaka
- Journal Title
  
  Pharmacogenomics J 3(3)
  
  Pages: 183-188
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Identification of highly expressed genes in peripheral blood T cells from patients with atopic dermatitis.2002
- Author(s)
  Matsumoto Y, Oshida T, Obayashi I, Imai Y, Matsui K, Yoshida NL, Nagata N, Ogawa K, Obayashi M, Kashiwabara T, Gunji S, Nagasu T, Sugita Y, Tanaka T, Tsujimoto G, Katsunuma T, Akasawa A, Saito H.
- Journal Title
  
  Int Arch Allergy Immunol 129(4)
  
  Pages: 327-340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene.2002
- Author(s)
  M.Hayashi, Y.Shimada, Y.Nishimura, T.Hama, T.Tanaka
- Journal Title
  
  Biochem.Biophys.Res.Commun. 297
  
  Pages: 1253-1258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003
[Journal Article] Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.2002
- Author(s)
  Imai Y, Nakada A, Hashida R, Sugita Y, Tanaka T, Tsujimoto G, Matsumoto K, Akasawa A, Saito H, Oshida T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 297
  
  Pages: 1282-1290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207003

1. TANAKA Toshio (00135443)

# of Collaborated Projects: 28 results

# of Collaborated Products: 7 results
2. NISHIMURA Yuhei (30303720)

# of Collaborated Projects: 14 results

# of Collaborated Products: 2 results
3. TSUNODA Hiroshi (20314114)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
4. HAYASHI Masaaki (80291417)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. INADA Hiroyasu (90283522)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. MUKAI Jun (70263019)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. HIDAKA Hiroyoshi (80100171)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. HEIZMANN C.W

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 中谷中 (80237304)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 松島聡 (50252367)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SHIMADA Yasuhito (40378427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. ISHIKAWA Naohisa (80109321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HAGIWARA Masatoshi (10208423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HAIZMANN C.W.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ASAHI Yoshihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. BERCHTOLD M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAKA Michiko 中 充子

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Molecular cell pharmacology of novel smooth muscle regulation moleculePrincipal Investigator

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Molecular cell pharmacology of gene expression in eosinophils by antiallergic drugs diseasesPrincipal Investigator

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NAKA Michiko 中充子