ITOU Riyoko 伊東理世子

… Alternative Names

ITO Riyoko 伊東理世子

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Researcher Number	10140865
Other IDs
Affiliation (based on the past Project Information) *help	2016: 福岡歯科大学, 口腔歯学部, 講師 2010 – 2015: 福岡歯科大学, 歯学部, 講師 2014: 福岡歯科大学, 口腔歯学部, 講師 2007 – 2010: Fukuoka Dental College, 歯学部, Research Associate 2004 – 2006: 福岡歯科大学, 歯学部, 助手 1997 – 2002: 福岡歯科大学, 歯学部, 助手
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / 遺伝 Except Principal Investigator Genetics/Genome dynamics / Molecular biology / 遺伝 / Molecular biology / Risk sciences of radiation and chemicals / Biological Sciences
Keywords	Principal Investigator mutation / アポトーシス / 抗がん剤 / 突然変異 / O^6-メチルグアニン / alkylated agent / apoptosis / DNA Repair / 細胞死 / ミスマッチ修復 … More / アルキル化剤 / アポソーシス / DNA修復 / mouse / anticancer agent / gene deficient / cell line / tumorigenesis / O^6-methylguanine / DNA repair enzyme / 発ガン / マウス / 遺伝子欠損 / 細胞株 / 発がん / DNA修復酵素 … More Except Principal Investigator DNA修復 / 突然変異 / 酸化ストレス / 遺伝子欠損マウス / RNA / ミスマッチ修復 / 発がん / 8-オキソグアニン / アポトーシス / 遺伝子ターゲティング / アルキル化剤 / 遺伝子 / MutT / NUDT5 / ヌクレオチド / がん / 品質管理 / 自然発がん / 酸化グアニン / メチルトランスフェラーゼ / 致死効果 / 塩基置換 / 変異タンパク / 酸化塩基 / 遺伝子障害 / 活性酸素 / expression / genetic information / quality control / mouse / ribonucleotide / oxidized guanine / oxidative stress / 発現 / 遺伝情報 / マウス / リボヌクレオチド / 8-oxo-guanine / nucleotides / oxidation / 酸化 / MTH1 gene / replication error / DNA replication / DNA precursor / 8-oxoguanine / mutation rate / spontaneous mutation / Reactive oxygen / DNA合成前駆体 / 胃がん / 自然突然変異率 / 酸化DNA損傷 / mutation / cancer / cell death / alkylating agents / gene-defective mice / mismatch repair / DNA repair enzyme / Carcinogen / 修復欠損 / 酸素マジカル / 検出・評価システム / 発がん物質 / DNA修復系 / 細胞株 / DVA修復系 / 発癌物質 / Mth1 / mutT / Auf1 / RNAの分解 / 酸化RNA / ノックアウト細胞株 / ヌクレオチド代謝 / 酸化ヌクレオチド / ８ーオキソグアニン / RNA 酸化 / ゲノム維持 / ゲノム構築 / 蛋白質 / 癌 / タンパク質 / ストレス / 酵素 / ゲノム / 核酸 / RNA結合タンパク質 / 分解酵素 / 発現異常 / 老化 / 前駆体ヌクレオチド / 酸化損傷 / 品質管理機構 / 異常タンパク / RNA結合蛋白 / RNA品質管理 / 質量分析 / DNA修復・損傷 / 核酸損傷 / 自然突然変異 / DNA酸化損傷 / 胸腺腫 / 修復遺伝子 / 細胞死 / DNA修復機構 Less

Cell death mechanism by RNA oxidative signal transduction
- Principal Investigator
  
  Sekiguchi Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyushu University
Genetic system for functioning to prevent aging
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Fukuoka Dental College
酸化ストレス下で、正常な複製や転写を保証する酵素の役割
- Principal Investigator
  
  高木康光
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Fukuoka Dental College
RNA damages and RNA quality control
- Principal Investigator
  
  HAYAKAWA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Mechanisms for quality control of RNA in mammalian cells
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Fukuoka Dental College
The mechanisms to eliminate oxidized nucleotides and maintenance of genetic information
- Principal Investigator
  
  ISHIBASHI Toru
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Biomolecular Engineering Research Institute
The mechanism of cell death inducedby O^6-methylguanine DNA : the role of MSH2 and MLH1 proteinsPrincipal Investigator
- Principal Investigator
  
  ITO Riyoko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Fukuoka Dental College
内在性発がん要因としての酸化グアニンとその排除の機構
- Principal Investigator
  
  高木康光
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Fukuoka Dental College
Development of a detection and evaluation system for carcinogens with the use of cell lines deficient in DNA repair genesPrincipal Investigator
- Principal Investigator
  
  ITOH Riyoko, 関口睦夫
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  遺伝
- Research Institution
  Fukuoka Dental College
発がん抑制におけるミスマッチ修復の役割
- Principal Investigator
  
  関口睦夫
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fukuoka Dental College
発がん抑制における突然変異制御遺伝子の役割
- Principal Investigator
  
  関口睦夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Fukuoka Dental College
酸素による遺伝子障害とその防御機構
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fukuoka Dental College
発がんにおける突然変異制御遺伝子系の役割
- Principal Investigator
  
  関口睦夫
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Fukuoka Dental College
Detection-evaluation systems for carcinogens with the use of gene-defective mice
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Mechanism for control of mutagenesis in mammals
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  遺伝
- Research Institution
  Fukuoka Dental College

All 2015 2013 2012 2011 2010 2009 2005 2004 Other

All Journal Article Presentation

[Journal Article] Elimination and utilization of oxidized guanine nucleotides in the synthesis of RNA and its precursors2013
- Author(s)
  Takeshi Sekiguchi, Riyoko Ito, Hiroshi Hayakawa, Mutsuo Sekiguchi
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 8128-8135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370003
[Journal Article] Search for proteins required for accurate gene expression under oxidative stress: Roles of guanylate kinase and RNA polymerase2013
- Author(s)
  Hchiro Inokuchi, Riyoko Ito, Tkeshi Sekiguchi, Mutsuo Skiguchi
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 46 Pages: 32952-32962
- DOI
  10.1074/jbc.m113.507772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370003, KAKENHI-PROJECT-24570160, KAKENHI-PROJECT-24657006
[Journal Article] Human MTH3(NUDT18) protein hydrolyzes oxidized forms of guanosine and deoxyguanosine diphosplate: Comparison with MTH1 and MTH22012
- Author(s)
  Yasumitsu Takagi, Daiki Setoyama, Riyoko Ito, Hiroshi Ｈａｙａｋａｗａ, Hiroyuki kamiya, Yuriko Yamagata, Mutsuo Sekiguchi
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Pages: 21541-21549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370003
[Journal Article] Cleavage of oxidized guanine nucleotide and ADP sugar by human NUDT5 protein2011
- Author(s)
  伊東理世子
- Journal Title
  
  J.Biochem
  
  Volume: 149 Pages: 731-738
- NAID
  10030585983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370003
[Journal Article] Human Proteins that Specifically Bind to 8-Oxoguanine-containing RNA and their Responses to Oxidative Stress.2010
- Author(s)
  Hiroshi Hayakawa, Aya Fujikane, Riyoko Ito, Masaki Matsumoto, Keiichi I.Nakayama, Mutsuo Sekiguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications 403
  
  Pages: 220-224
- Data Source
  KAKENHI-PROJECT-20570168
[Journal Article] Mammalian enzymes for preventing transcriptional errors caused by oxidative damage.2005
- Author(s)
  Ishibashi T., Hayakawa H., Ito R., Miyazawa M., Ymagata Y., Sekiguchi M.
- Journal Title
  
  Nucleic Acids Research 33
  
  Pages: 3799-3784
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570149
[Journal Article] Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.2005
- Author(s)
  Ito R., Hyakawa H., Sekiguchi M., Ishibashi T.
- Journal Title
  
  Biochemistry 44
  
  Pages: 6670-6674
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16570149
[Journal Article] Mammalian enzymes for preventing transcriptional errors caused by oxidative damage.2005
- Author(s)
  Ishibashi T., Hayakawa H., Ito R., Miyazawa M., Ymamagata Y., Sekiguchi M.
- Journal Title
  
  Nucleic Acids Res. vol.33
  
  Pages: 3779-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570149
[Journal Article] Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools2005
- Author(s)
  Ito R, Hayakawa H, Sekiguchi M, Ishibashi T.
- Journal Title
  
  Biochemistry 44(17)
  
  Pages: 6670-6674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591902
[Journal Article] Mammalian enzymes for preventing transcriptional errors caused by oxidative damage2005
- Author(s)
  Ishibashi T, Hayakawa H, Ito R, Miyazawa M, Yamagata Y, Sekiguchi M.
- Journal Title
  
  Nucleic Acids Res. 33(12)
  
  Pages: 3779-3784
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591902
[Journal Article] Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.2005
- Author(s)
  Ito, R., Hayakawa, H., Sekiguchi, M., Ishibashi, T.
- Journal Title
  
  Biochemistry 44・17
  
  Pages: 6670-6674
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591902
[Journal Article] Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.2005
- Author(s)
  Ito Riyoko
- Journal Title
  
  Biochemistry 44・17
  
  Pages: 6670-6674
- Data Source
  KAKENHI-PROJECT-16570149
[Journal Article] Mammalian enzymes for preventing transcriptional errors caused by oxdative damage.2005
- Author(s)
  Ishibashi, T., Hayakawa, H., Ito, R., Miyazawa, M., Yamagata, Y., Sekiguchi, M.
- Journal Title
  
  Nucleic Acid Research 33・12
  
  Pages: 3779-3784
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591902
[Journal Article] Mammalian enzymes for preventing transcriptional errors caused by oxdative damage.2005
- Author(s)
  Ishibashi, T., Hayakawa, H., Ito, R., Miyazawa, M., Yamagata, Y., Sekiguchi, M.
- Journal Title
  
  Nucleic Acid research 33・12
  
  Pages: 3779-3784
- Data Source
  KAKENHI-PROJECT-16591902
[Journal Article] Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.2005
- Author(s)
  Ito R., Hayakawa H., Sekiguchi M., Ishibashi T.
- Journal Title
  
  Biochemistry vol.44
  
  Pages: 6670-6674
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16570149
[Journal Article] Killing and mutagenic actions of dacarbazine, a chemotherapeutic alkylating agent, on human and mouse cells : effects of Mgmt and Mlh1 mutations.2004
- Author(s)
  Sanada, M., Takagi, Y., Ito, R., Sekiguchi, M.
- Journal Title
  
  DNA Repair 3
  
  Pages: 413-120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591902
[Journal Article] Killing and mutagenic actions of dacarbazine, a chemotherapeutic alkylating agent, on human and mouse cells : effects of Mgmt and Mlh1 mutations2004
- Author(s)
  Sanada M, Takagi Y, Ito R, Sekiguchi M.
- Journal Title
  
  DNA Repair 3
  
  Pages: 413-420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591902
[Presentation] 活性酸素による突然変異の生起とその抑制.2015
- Author(s)
  伊東理世子、橋口一成、関口睦夫.
- Organizer
  第 38回日本分子生物学会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 変異原性ヌクレオチドはどこへ行くのか？2015
- Author(s)
  関口睦夫、伊東理世子、関口猛、早川浩、井口八郎
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  仙台
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 大腸菌における8-オキソグアニンを含むヌクレオチドの排除機構2013
- Author(s)
  伊東理世子、井口八郎、関口猛、関口睦夫
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶應義塾大学日吉キャンパス（横浜市港北区）
- Data Source
  KAKENHI-PROJECT-22370003
[Presentation] 酸素ストレス下の遺伝子発現機構2013
- Author(s)
  井口八郎、伊東理世子、関口猛、関口睦夫
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶應義塾大学日吉キャンパス（横浜市港北区）
- Data Source
  KAKENHI-PROJECT-22370003
[Presentation] 酸化ストレスによるRNAの異常を防ぐ酵素系2012
- Author(s)
  伊東理世子、高木康光、瀬戸山大樹、早川浩、関口睦夫
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  九州大学医学部
- Data Source
  KAKENHI-PROJECT-22370003
[Presentation] Cleavage of oxidized nucleotides for prevention of mutation2011
- Author(s)
  R.Ito, Y.Takagi, T.Arimori, Y.Yamagata, M.Sekiguchi, H.Hayakawa
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22370003
[Presentation] Characterization of human NUDT5 that hydrolyzes oxidized nucleotides2011
- Author(s)
  伊東理世子、関口睦夫、山縣ゆり子、中津可道、早川浩
- Organizer
  日本遺伝学会
- Place of Presentation
  京都大学
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22370003
[Presentation] Specific binding of human proteins to 8-oxoguanine-containing RNA2011
- Author(s)
  A.Fujikane, H.Hayakawa, R.Ito, K.Nakayama, M.Sekiguchi
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22370003
[Presentation] Mammalian proteins for eliminating oxidized forms of RNA and its precursors for accurate protein synthesis2009
- Author(s)
  Hiroshi Hayakawa, Riyoko Ito, Mutsuo Sekiguchi
- Organizer
  アメリカ微生物学会(ASM) : The 3^<rd> ASM Conference on DNA Repair and Mutagenesis.(Poster Session)
- Place of Presentation
  カナダ(ウィスラー)
- Data Source
  KAKENHI-PROJECT-20570168
[Presentation] 酸化されたRNAやRNA前駆体を生体から排除し、正確な遺伝情報伝達を保証するヒトのタンパク質群2009
- Author(s)
  早川浩、伊東理世子、関口睦夫
- Organizer
  日本遺伝学会81回大会(ワークショップ)
- Place of Presentation
  長野県松本市信州大学理学部
- Data Source
  KAKENHI-PROJECT-20570168
[Presentation] Human Proteins that Specifically Bind to 8-Oxoguanine-containing RNA and their Responses to Oxidative Stress.
- Author(s)
  Hiroshi Hayakawa, Aya Fujikane, Riyoko Ito, Masaki Matsumoto, Keiichi I.Nakayama, Mutsuo Sekiguchi
- Organizer
  第33回日本分子生物学会・第83回日本生化学学会合同大会
- Data Source
  KAKENHI-PROJECT-20570168

1. SEKIGUCHI Mutsuo (00037342)

# of Collaborated Projects: 11 results

# of Collaborated Products: 18 results
2. SHIMOKAWA Hidetoshi (50122792)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. SANADA Masayuki (40084264)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
4. TAKAGI Yasumitsu (20212003)

# of Collaborated Projects: 6 results

# of Collaborated Products: 5 results
5. HAYAKAWA Hiroshi (70150422)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. 瀬戸山大樹 (30550850)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. Sekiguchi Takeshi (60187846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. TSUZUKI Teruhisa (40155429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ISHIBASHI Toru (90369041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. HIDAKA Masumi (80238310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 石井健士 (70516731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 作見邦彦 (50211933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ITOU Riyoko 伊東 理世子

ITO Riyoko 伊東 理世子

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The mechanism of cell death inducedby O^6-methylguanine DNA : the role of MSH2 and MLH1 proteinsPrincipal Investigator

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[Journal Article] Elimination and utilization of oxidized guanine nucleotides in the synthesis of RNA and its precursors2013

Author(s)

ITOU Riyoko 伊東理世子

ITO Riyoko 伊東理世子