Irifune Masahiro 入舩正浩

… Alternative Names

Researcher Number	10176521
Other IDs	https://orcid.org/0000-0001-9646-2418
Affiliation (Current)	2022: 広島大学, 医系科学研究科(歯), 名誉教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 広島大学, 医系科学研究科(歯), 教授 2017 – 2018: 広島大学, 医歯薬保健学研究科(歯), 教授 2015 – 2016: 広島大学, 医歯薬保健学研究院(歯), 教授 2014: 広島大学, 医歯薬保健学研究院, 教授 2014: 広島大学, 大学院医歯薬保健学研究院(歯), 教授 … More
Review Section/Research Field	Principal Investigator Surgical dentistry / Functional basic dentistry / Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Surgical dentistry
Keywords	Principal Investigator 正向反射 / 不動化 / GABA / 全身麻酔作用 / サブスタンスP / MK-801 / Ketamine / マイクロダイアリシス法 / 鎮痛作用 / α2-アドレナリン受容体作動薬 … More Except Principal Investigator ドパミン / L-DOPA / MPP+ / 全身麻酔 / 正向反射 / 不動化 / 麻酔作用 / 筋弛緩 / ドパミン受容体 / 意識消失 / 国際情報交換(米国） / オピオイド / ニューロトランスミッター / ノルアドレナリン / アセチルコリン / セロトニン / (Na^++K^+)-ATPase / シナプトソーム / ミューオピオイド / 遊離機構 / (Na^++K^+)-ATPase活性に対する影響 / opioids / neurotransmission / noradrenaline / acetylcholine / serotonin / (Na^++K^+) -ATPase / synaptosome / アラキドン酸 / モノアミントランスポータ / MPP^+ / インドメタシン / アスピリン / デシプラミン / モノアミントランスポーター / シクロオキシゲナーゼ / リドカイン / コカイン / 痙攣 / Arachidonoc acid / Monoamine transporter / Indomethacin / Ibuprofen / Dopamine / Desipramine Less

Development of a control method for depth of anesthesia and/or sedation applied to a selective dopamine receptor subtype ligand.Principal Investigator
- Principal Investigator
  
  入舩正浩
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Development of a novel general anesthetic method of applying the enhancement of descending pain suppression system by stimulation of dopamine neurons of the nucleus accumbensPrincipal Investigator
- Principal Investigator
  
  Irifune Masahiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Hiroshima University
Development of a novel general anesthetic method applying the enhancement of descending pain suppression system: Utilization of 5-HT receptor ligandsPrincipal Investigator
- Principal Investigator
  
  Irifune Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Selective ligand of dopamine receptor subtype gives to anesthetic action.
- Principal Investigator
  
  OGAWA Yoshitaka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
The elucidation of role of motor neurons or pain pathways of the spinal cord in analgesia, muscle reluxation, and immobility as general anesthetic factorsPrincipal Investigator
- Principal Investigator
  
  IRIFUNE MASAHIRO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
The role of substance P in analgesia and immobility induced by general anesthetic agentsPrincipal Investigator
- Principal Investigator
  
  IRIFUNE Masahiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hiroshima University
Clarification of mechanisms of analgesia and immobility induced by general anesthesia, and exploration of new anesthetic methodsPrincipal Investigator
- Principal Investigator
  
  IRIFUNE Masahiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Regulation of dopamine transporter function and its role in neuronal diseases - Regulation by arachidonic acid.
- Principal Investigator
  
  DOHI Toshihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
The Role of GABA and Glutamate Neurons in General Anesthetic ActionPrincipal Investigator
- Principal Investigator
  
  KAWAHARA Michio, 入船正浩
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
The role of GABA neurons in general anesthesia: an in vivo microdialysis studyPrincipal Investigator
- Principal Investigator
  
  IRIFUNE Masahiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Hiroshima University
Studies of excitement actions of N-methyl-D-aspartate antagonistsPrincipal Investigator
- Principal Investigator
  
  IRIFUNE Masahiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  HIROSHIMA UNIVERSITY
  Kagoshima University
Studies on the effect of opioids on the output of several neurotransmitters
- Principal Investigator
  
  NISHIKAWA Takashige
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kagoshima University

[Book] 第5版　臨床歯科麻酔学2019
- Author(s)
  入舩正浩
- Total Pages
  23
- Publisher
  永末書店
- ISBN
  9784816013560
- Data Source
  KAKENHI-PROJECT-18K09812
[Book] 第8版　歯科麻酔学2019
- Author(s)
  入舩正浩
- Total Pages
  8
- Publisher
  医歯薬出版株式会社
- ISBN
  9784263458297
- Data Source
  KAKENHI-PROJECT-18K09812
[Book] 脳血管障害，歯科におけるくすりの使い方　2015-20182014
- Author(s)
  入舩正浩
- Total Pages
  456
- Publisher
  デンタルダイヤモンド社
- Data Source
  KAKENHI-PROJECT-24593056
[Book] 第7版　歯科麻酔学2011
- Author(s)
  入舩正浩
- Total Pages
  4
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-23592992
[Book] 全身麻酔薬の作用機序、歯科麻酔学第7版2011
- Author(s)
  入舩正浩
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-23592992
[Book] 歯科麻酔学第7版(全身麻酔薬の作用機序)2010
- Author(s)
  入舩正浩
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20592373
[Journal Article] Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells.2020
- Author(s)
  Takahashi, T., Yoshida, T., Harada, K., Miyagi, T., Hashimoto, K., Hide, I., Tanaka, S., Irifune, M. and Sakai, N.
- Journal Title
  
  PLOS ONE
  
  Volume: 15
- DOI
  10.1371/journal.pone.0242349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03409, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-18K07392, KAKENHI-PROJECT-18K09812
[Journal Article] The indirect γ-aminobutyric acid (GABA) receptor agonist gabaculine-induced loss of the righting reflex may inhibit the descending analgesic pathway.2020
- Author(s)
  Ogawa, Y., Irifune, M., Mukai, A., Shimizu, Y., Doi, M., Oue, K., Yoshida, M., Kanematsu, T., Morioka, M., Nakata, Y. and Sakai, N.
- Journal Title
  
  Pharmacol. Biochem. Behav.
  
  Volume: 198 Pages: 173034-173034
- DOI
  10.1016/j.pbb.2020.173034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03409, KAKENHI-PROJECT-18K09812
[Journal Article] SKF-10047, a prototype Sigma-1 receptor agonist, augmented the membrane trafficking and uptake activity of the serotonin transporter and its C-terminus-deleted mutant via a Sigma-1 receptor-independent mechanism.2019
- Author(s)
  Asano Masaya、Motoike Serika、Yokota Chika、Usuki Naoto、Yamamoto Hikaru、Urabe Tomoaki、Katarao Kazusa、Hide Izumi、Tanaka Shigeru、Kawamoto Masashi、Irifune Masahiro、Sakai Norio
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 139 Pages: 29-36
- DOI
  10.1016/j.jphs.2018.11.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07392, KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-16K15318, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-19H03409
[Journal Article] Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure.2019
- Author(s)
  Kanematsu T, Oue K, Okumura T, Harada K, Yamawaki Y, Asano S, Mizokami A, Irifune M, Hirata M
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 61(2) Pages: 65-72
- DOI
  10.1016/j.job.2019.04.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-17K19766, KAKENHI-PROJECT-17H01595, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-17K17254
[Journal Article] Management of an Internal Carotid Artery Injury Caused by a Displaced Titanium Plate With a Combination of Interventional Vascular Radiology and Surgery.2018
- Author(s)
  Shimizu Y, Okazaki T, Hamana T, ando Irifune M
- Journal Title
  
  J Oral Maxillofac Surg
  
  Volume: 76
- DOI
  10.1016/j.joms.2018.02.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11875, KAKENHI-PROJECT-18K09812
[Journal Article] Propofol induced diverse and subtype-specific translocation of PKC families2018
- Author(s)
  Miyahara T, Adachi N, Seki T, Hide I, Tanaka S, Saito N, Irifune M, Sakai N
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 印刷中 Pages: 20-29
- DOI
  10.1016/j.jphs.2018.03.008
- NAID
  120006488442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08234, KAKENHI-PROJECT-18K06891, KAKENHI-PROJECT-18K07392, KAKENHI-PROJECT-18K09812, KAKENHI-PROJECT-16H05133, KAKENHI-PROJECT-16K15318
[Journal Article] Effective Postoperative Analgesia Using Intravenous Flurbiprofen and Acetaminophen.2018
- Author(s)
  Yoshida M, Shimizu Y, Yoshida K, Mukai A, Doi M, Irifune M.
- Journal Title
  
  J Oral Maxillofac Surg
  
  Volume: 76(9) Pages: 1869-1872
- DOI
  10.1016/j.joms.2018.03.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09812
[Journal Article] Phospholipase C-related catalytically inactive protein-knockout mice exhibit uncoupling protein 1 upregulation in adipose tissues following chronic cold exposure2017
- Author(s)
  Kana Oue, Yosuke Yamawaki, Satoshi Asano, Mizokami Akiko, Masato Hirata, Masahiro Irifune, Takashi Kanematsu.
- Journal Title
  
  J Oral Biosci
  
  Volume: 印刷中 Pages: 108-112
- DOI
  10.1016/j.job.2017.04.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20421
[Journal Article] General anesthetic actions on GABAA receptors in vivo are reduced in phospholipase C-related catalytically inactive protein knockout mice2017
- Author(s)
  Hayashiuchi M, Kitayama T, Morita K, Yamawaki Y, Oue K, Yoshinaka T, Asano S, Harada K, Kang Y, Hirata M, Irifune M, Okada M, Kanematsu T.
- Journal Title
  
  Jpn Dent Sci Rev
  
  Volume: in press Pages: 18-24
- DOI
  10.1007/s00540-017-2350-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K17254, KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K11313
[Journal Article] A Case With Deteriorating Palmoplantar Pustulosis and Hyperthyroidism After Simultaneous Bimaxillary Orthognathic Surgery2017
- Author(s)
  Oda A, Yoshida K, Uno T, Yoshinaka T, Mukai A, Irifune M
- Journal Title
  
  Anesth Prog
  
  Volume: 64 Pages: 173-174
- DOI
  10.2344/anpr-64-03-03
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11313
[Journal Article] Phospholipase C-related Catalytically Inactive Protein Is a New Modulator of Thermogenesis Promoted by β-Adrenergic Receptors in Brown Adipocytes.2016
- Author(s)
  Kana Oue, Jun Zhang, Kae Harada-Hada, Satoshi Asano, Yosuke Yamawaki, Masaki Hayashiuchi, Hisako Furusho, Takashi Takata, Masahiro Irifune, Masato Hirata, Takashi Kanematsu
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 291 Pages: 4185-4196
- DOI
  10.1074/jbc.m115.705723
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11039, KAKENHI-PROJECT-15K19731, KAKENHI-PROJECT-15H06433, KAKENHI-PROJECT-26670809, KAKENHI-PROJECT-24229009, KAKENHI-PROJECT-15K20372, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-16K20437
[Journal Article] Selective blockade of N-methyl-D-aspartate channels in combination with dopamine receptor antagonism induces loss of the righting reflex in mice, but not immobility2015
- Author(s)
  Kikuchi N, Irifune M, Shimizu Y, Yoshida K, Morita K, Kanematsu T, Morioka N, Nakata Y, Sakai N.
- Journal Title
  
  Psychopharmacology
  
  Volume: 232(1) Pages: 39-46
- DOI
  10.1007/s00213-014-3634-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24593056, KAKENHI-PROJECT-15K11313, KAKENHI-PROJECT-25293061
[Journal Article] Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase2014
- Author(s)
  Okumura T; Harada K; Oue K; Zhang J; Asano S; Hayashiuchi M; Mizokami A; Tanaka H; Irifune M; Kamata N; Hirata M; Kanematsu T
- Journal Title
  
  PLoS One
  
  Volume: 9(6)
- Data Source
  KAKENHI-PROJECT-24593056
[Journal Article] An appropriate compression pace is important for securing the quality of hands-only CPR--a manikin study2014
- Author(s)
  Shimizu Y; Tanigawa K; Ishikawa M; Ouhara K; Oue K; Yoshinaka T; Kurihara H; Irifune M
- Journal Title
  
  Hiroshima J Med Sci
  
  Volume: 63(1-3) Pages: 7-11
- NAID
  120005601177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593056
[Journal Article] 麻酔導入により急性心不全となり肥大型心筋症が判明したダウン症の1症例2008
- Author(s)
  清水慶隆, 入舩正浩, 土井充, 河原道夫, 久留島秀治, 谷川攻一
- Journal Title
  
  臨床麻酔 32巻
  
  Pages: 1647-1650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592373
[Journal Article] MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility.2007
- Author(s)
  Irifune M, et. al.
- Journal Title
  
  Can J Anaesth 54(12)
  
  Pages: 998-1005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility.2007
- Author(s)
  Irifune M, et. al.
- Journal Title
  
  Can J Anesth 54(12)
  
  Pages: 998-1005
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice.2007
- Author(s)
  Irifune M, et. al.
- Journal Title
  
  Anesth Analg 104(6)
  
  Pages: 1415-1421
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility2007
- Author(s)
  Irifune, M., Katayama, S., Takarada, T., Shimizu, Y., Endo, C., Takata, T., Morita, K., Dohi, T., Sato, T., Kawahara, M
- Journal Title
  
  Can J Anaesth 54(12)
  
  Pages: 998-1005
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice2007
- Author(s)
  Irifune, M., Kikuchi, N., Saida, T., Takarada, T., Shimizu, Y., Endo, C., Morita, K., Dohi, T., Sato, T., Kawahara, M
- Journal Title
  
  Anesth Analg 104(6)
  
  Pages: 1415-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] Increased gamma-aminobutyric acid levels in mouse brain induce loss of righting reflex, but not immobility, in response to noxious stimulation2007
- Author(s)
  Katayama, S., Irifune, M., Kikuchi, N., Takarada, T., Shimizu, Y., Endo, C., Takata, T., Debi, T., Sato, T., Kawahara, M
- Journal Title
  
  Anesth Analg 104(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] Riluzole, a Glutamate Release Inhibitor, Induces Loss of Righting Reflex, Antinociception, and Immobility in Response to Noxious Stimulation in Mice2007
- Author(s)
  Masahiro Irifune
- Journal Title
  
  Anesthesia ＆ Analgesia 104・5(in press)
- Data Source
  KAKENHI-PROJECT-18592037
[Journal Article] Selective blockade of N-methyl-D-aspartate channels in combination with dopamine receptor antagonism induces loss of the righting reflex in mice, but not immobility
- Author(s)
  Kikuchi, Nobuhito; Irifune, Masahiro; Shimizu, Yoshitaka; Yoshida, Keita; Morita, Katsuya; Kanematsu, Takashi; Morioka, Norimitsu; Nakata, Yoshihiro; Sakai, Norio
- Journal Title
  
  Psychopharmacology
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-23592992
[Presentation] Functional regulation of serotonin transporter by SNARE protein Syntaxin 3.2020
- Author(s)
  Motoike S, Taguchi K, Urabe T, Harada K, Hide I, Tanaka S, Irifune M, Sakai N
- Organizer
  The 93rd Annual Meeting of the Japanese Pharmacological Society
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] Perineural treatment with anti-HMGB1 antibody alleviates nociceptive-like behaviors in mice with chronic constriction injury of distal infraorbital nerve.2020
- Author(s)
  Nakamura Y, Nakashima K, Liu K, Waki H, Nishibori M, Irifune M, Morioka N
- Organizer
  The 93rd Annual Meeting of the Japanese Pharmacological Society
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] ラット脊髄後角神経からのサブスタンスP遊離に及ぼす麻酔関連薬の影響：in vitroおよびin vivo実験による検討2020
- Author(s)
  向井友宏，佐々木詩佳，今戸瑛二, 入舩正浩
- Organizer
  第59回広島県歯科医学会・第104回広島大学歯学会例会
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] The effect of tranexamic acid during sagittal split ramus osteotomy2019
- Author(s)
  Yoshida M, Ono S, Shimizu Y, Yoshida K, Mukai A, Doi M, Irifune M
- Organizer
  97th International Association for Dental Research General Session
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] GABA神経作動薬によるマウスの不動化は脳波解析による中枢神経抑制の強さとは無関係である2019
- Author(s)
  好中大雅, 向井明里，入舩正浩
- Organizer
  第46回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] GABA神経作動薬によるマウスの不動化は脳波解析による中枢神経抑制の強さと関係するか？－propofolとgabaculineの比較－2019
- Author(s)
  入舩正浩，好中大雅，向井明里
- Organizer
  第34回中国・四国歯科麻酔研究会
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] Perioperative anesthesia management for an autism spectrum disorder patient who was thought to be difficult to be hospitalized2019
- Author(s)
  Oda A, Yoshida K, Kouch T, Mukai T, Kikuchi Y, Takahashi T, Yoshinaka T, Oue K, Mukai A, Shimizu C, Oda Y, Okada Y, Irifune M
- Organizer
  The Asia Association for Disability and Oral Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] メタンフェタミンの鎮痛作用におけるノルアドレナリン神経の関与：ホルマリンテストによる検討2018
- Author(s)
  小田　綾，入舩正浩
- Organizer
  第33回中国・四国歯科麻酔研究会
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] メタンフェタミンの鎮痛作用におけるドパミン神経の関与：ホルマリンテストによる検討2018
- Author(s)
  小田　綾，入舩正浩
- Organizer
  第46回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] Prediction of prognosis following perioperative dental injury - comparison of anesthesiologists and dentists.2018
- Author(s)
  Saeki N, Shimizu Y, Yoshida M, Yoshida K, Moriwaki N, Kawamoto M, Irifune M
- Organizer
  The International Anesthesia Research Society (IARS) 2018 Annual Meeting and International Science Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] 各種神経作動薬による行動薬理作用と脳波・筋電位変化の関係解析2018
- Author(s)
  菊池友香, 好中大雅, 入舩正浩
- Organizer
  第46回日本歯科麻酔学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K09812
[Presentation] ラット脊髄後角神経からのサブスタンスP遊離に及ぼす静脈麻酔薬の影響2017
- Author(s)
  向井友宏、小川雄也、入舩正浩
- Organizer
  第32回中国・四国歯科麻酔研究会
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] Overexpression of PRIP in MCF-7 cells, a breast cancer cell line, enhances cisplatin-induced apoptosis2017
- Author(s)
  Maetani Y, Asano S, Irifune M, Kanematsu T
- Organizer
  第50回広島大学歯学会総会
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] カラゲナン誘発性ラット慢性咬筋筋痛モデル2017
- Author(s)
  吉田充広、向井明里、吉田啓太、土井　充、清水慶隆、入舩正浩
- Organizer
  第32回中国・四国歯科麻酔研究会
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] GABAA受容体サブユニット構成の違いによる全身麻酔薬の薬理効果の相違2016
- Author(s)
  林内優樹, 好中大雅, 大植香菜, 尾田友紀, 入舩正浩
- Organizer
  第44回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  札幌市
- Year and Date
  2016-10-29
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] 鎮静や全身麻酔中の侵害刺激時に脳内で何が起きているか？2016
- Author(s)
  入舩正浩，好中大雅，石井裕明
- Organizer
  第31回中国・四国歯科麻酔研究会
- Place of Presentation
  広島市
- Year and Date
  2016-07-31
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] Prip遺伝子欠損マウスにおけるGABA作動性麻酔薬の作用変化2016
- Author(s)
  林内優樹, 岡田貢, 兼松隆, 入舩正浩
- Organizer
  第33回日本障害者歯科学会総会・学術大会
- Place of Presentation
  大宮市
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] GABAA受容体作動薬投与による全身麻酔下では、痛み刺激は脳波を覚醒へ向わせる2016
- Author(s)
  好中大雅菊池友香, 小川雄也, 林内優樹, 入舩正浩
- Organizer
  第44回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  札幌市
- Year and Date
  2016-10-29
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] The analgesic effect of flurbiprofen with fentanil or with acetaminophen2016
- Author(s)
  Yoshida M, Shimizu Y, Yoshida K, Mukai A, Doi M, Irifune M
- Organizer
  The 94th General Session & Exhibition of The IADR
- Place of Presentation
  Seoul, Republic of Korea
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] マウスの脳波と筋電図に及ぼすプロポフォールの影響2015
- Author(s)
  好中大雅, 入舩正浩
- Organizer
  第43回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15K11313
[Presentation] Mice lacking phospholipase C-related but catalytically inactive protein (PRIP) are protected from high-fat diet-induced obesity2014
- Author(s)
  Oue K; Irifune M; Kanematsu T
- Organizer
  第47回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2014-06-21
- Data Source
  KAKENHI-PROJECT-24593056
[Presentation] 選択的NMDAチャネル遮断とドパミン受容体拮抗作用の併用はマウスの正向反射を消失させるが、不動化は生じない2013
- Author(s)
  入舩正浩
- Organizer
  第28回中国・四国歯科麻酔研究会
- Place of Presentation
  広島
- Year and Date
  2013-07-15
- Data Source
  KAKENHI-PROJECT-23592992
[Presentation] 選択的 NMDA チャネル遮断とドパミン受容体拮抗作用の併用はマウスの正向反射を消失させるが、不動化は生じない2013
- Author(s)
  入舩正浩
- Organizer
  第 28 回中国・四国歯科麻酔研究会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-24593056
[Presentation] プロポフォール誘発性εPKCトランスロケーションにおけるC1ドメインの役割2012
- Author(s)
  宮原岳史, 入舩正浩, 酒井規雄, 齋藤尚亮
- Organizer
  日本歯科麻酔学会総会・学術集会
- Place of Presentation
  アクロス福岡
- Data Source
  KAKENHI-PROJECT-24593056
[Presentation] プロポフォール誘発性εPKCトランスロケーションにおけるC1ドメインの役割2012
- Author(s)
  宮原岳史,入舩正浩,酒井規雄,齋藤尚亮
- Organizer
  第40回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2012-10-06
- Data Source
  KAKENHI-PROJECT-23592992
[Presentation] プロテインキナーゼCのトランスロケーションと酵素活性に対するプロポフォールの効果2011
- Author(s)
  宮原岳史,関貴弘,秀和泉,田中茂,齊藤尚亮,入船正浩,酒井規雄
- Organizer
  第120回日本歯科薬理学会近畿部会
- Place of Presentation
  京都
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23592992
[Presentation] Pentobarbitalが引き起こす麻酔要素におけるGABA、グリシン、神経性コリン作動性、グルタミン酸およびサブスタンスP各神経の役割2011
- Author(s)
  向井明里,入舩正浩,宮原岳史,大植香菜,石井裕明,土井充,清水慶隆,吉田啓太,福島怜子,西中村亮
- Organizer
  第39回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-23592992
[Presentation] プロテインキナーゼC(PKC)のトランスロケーションと酵素活性に対するプロポフォールの影響2011
- Author(s)
  宮原岳史,酒井規雄,入舩正浩
- Organizer
  第39回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  神戸
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-23592992
[Presentation] 麻酔要素の発現におけるGABA神経の役割-ペントバルビタールと選択的作用薬の違い-2010
- Author(s)
  入舩正浩, 他
- Organizer
  第43回広島大学歯学会総会
- Place of Presentation
  広島大学歯学部大講義室
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] 麻酔要素の発現におけるGABA神経の役割-ペントバルビタールと選択的作用薬の違い-2010
- Author(s)
  入舩正浩, 向井明里, 宮原岳史, 大植香菜, 土井充, 清水慶隆, 齊田拓也, 三浦完菜, 西中村亮, 福島怜子
- Organizer
  第43回広島大学歯学会総会
- Place of Presentation
  広島
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] ペントバルビタールの麻酔要素発現におけるGABAおよびグリシン神経の役割2010
- Author(s)
  入舩正浩, 向井明里, 宮原岳史, 大植香菜, 土井充, 清水慶隆, 齊田拓也, 三浦完菜, 西中村亮, 福島怜子
- Organizer
  第25回中国・四国歯科麻酔研究会
- Place of Presentation
  広島
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] ペントバルビタールの麻酔要素発現におけるGABAおよびグリシン神経の役割2010
- Author(s)
  入舩正浩, 他
- Organizer
  第25回中国・四国歯科麻酔研究会
- Place of Presentation
  広島大学廣仁会館
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] ペントバルビタールが引き起こす麻酔要素に及ぼすGABAグリシンおよび神経性ニコチン受容体リガンドの影響2010
- Author(s)
  向井明里, 入舩正浩, 他
- Organizer
  第38回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  横須賀芸術劇場・産業交流プラザ
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] ペントバルビタールが引き起こす麻酔要素に及ぼすGABA,グリシンおよび神経性ニコチン受容体リガンドの影響2010
- Author(s)
  向井明里, 入舩正浩, 宮原岳史, 大植香菜, 土井充, 清水慶隆, 齊田拓也, 三浦完菜, 西中村亮, 福島怜子
- Organizer
  第38回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  横須賀
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] 内因性神経伝達物質と選択的受容体作動薬が引き起こす行動薬理作用の質の違い-特に運動亢進と麻酔作用について-2009
- Author(s)
  入舩正浩, 向井明里, 清水慶隆, 齊田拓也, 土井充, 新井由起子, 三浦完菜, 宮原岳史, 福島怜子
- Organizer
  第6回日本歯科麻酔学会中国・四国地方会
- Place of Presentation
  岡山
- Year and Date
  2009-07-05
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] 内因性神経伝達物質と選択的受容体作動薬が引き起こす行動薬理作用の質の違い-特に運動亢進と麻酔作用について-2009
- Author(s)
  入舩正浩, 他
- Organizer
  第6回日本歯科麻酔学会中国・四国地方会
- Place of Presentation
  岡山大学歯科外来診療棟
- Year and Date
  2009-07-05
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] 全身麻酔要素の一つである不動化におけるサブスタンスPの役割-脊髄後根神経節培養細胞からのサブスタンスP遊離に及ぼすpentobarbitalの影響-2008
- Author(s)
  鬼塚千織子, 入舩正浩, 齊田拓也, 向井明里, 井上敦子, 仲田義啓
- Organizer
  第36回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] ラット一次求心性神経からのサブスタンスP遊離に及ぼす全身麻酔薬の影響2008
- Author(s)
  鬼塚千織子, 入舩正浩, 井上敦子, 仲田義啓, 河原道夫
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-20592373
[Presentation] The involvement of mu-opioid and alpha(2)-adrenergic receptors in inducing immobility as one of anesthetic components2007
- Author(s)
  Onitsuka, C., Irifune, M., Morita, K., et. al.
- Organizer
  The 80th Annual Meeting of The Japanese Pharmacological Society
- Place of Presentation
  Nagoya, Japan
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592037
[Presentation] 選択的N-methyl-D-aspartate(NMDA)受容体チャネル遮断薬MK-801の全身麻酔作用の検討2006
- Author(s)
  入舩正浩, 他
- Organizer
  第34回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  横浜
- Year and Date
  2006-10-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592037
[Presentation] ペントバルビタール鎮静下で侵害刺激により促進されたマウス側坐核ドパミン遊離は、正向反射消失下で抑制される
- Author(s)
  石井裕明, 入舩正浩
- Organizer
  第４２回日本歯科麻酔学会総会・学術集会
- Place of Presentation
  新潟
- Year and Date
  2014-10-10 – 2014-10-12
- Data Source
  KAKENHI-PROJECT-24593056
[Presentation] 選択的NMDAチャネル遮断とドパミン受容体拮抗作用の併用はマウスの正向反射を消失させるが、不動化は生じない
- Author(s)
  入舩正浩
- Organizer
  第28回中国・四国歯科麻酔研究会
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-23592992

1. KAWAHARA Michio (30034094)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. DOHI Toshihiro (00034182)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
3. MORITA Katsuya (10116684)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 兼松隆 (10264053)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. OGAWA Yoshitaka (10294597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NISHIKAWA Takashige (10034191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 北山滋雄 (80177873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 向井明里 (30789251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吾郷由希夫 (50403027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANAKA Shigeru

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. HARADA Kana

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. OUE KANA

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
13. FURUSHO Hisako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. KATARAO kazusa

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. ASANO masaya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. MOTOIKE serika

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. URABE tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 山脇洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
19. 浅野智志

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
20. 溝上顕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 原田佳枝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 浜名智昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 秀和泉

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
24. 酒井規雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
25. 平田雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Irifune Masahiro 入舩 正浩

IRIFUNE Masahiro 入舩 正浩

入船 正浩 イリフネ マサヒロ

入舩 正浩 イリフネ マサヒロ

Research Projects

Research Products

Co-Researchers

Development of a control method for depth of anesthesia and/or sedation applied to a selective dopamine receptor subtype ligand.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of a novel general anesthetic method of applying the enhancement of descending pain suppression system by stimulation of dopamine neurons of the nucleus accumbensPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel general anesthetic method applying the enhancement of descending pain suppression system: Utilization of 5-HT receptor ligandsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Selective ligand of dopamine receptor subtype gives to anesthetic action.

Principal Investigator

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Research Field

Research Institution

The elucidation of role of motor neurons or pain pathways of the spinal cord in analgesia, muscle reluxation, and immobility as general anesthetic factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of substance P in analgesia and immobility induced by general anesthetic agentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of mechanisms of analgesia and immobility induced by general anesthesia, and exploration of new anesthetic methodsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Regulation of dopamine transporter function and its role in neuronal diseases - Regulation by arachidonic acid.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Role of GABA and Glutamate Neurons in General Anesthetic ActionPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

The role of GABA neurons in general anesthesia: an in vivo microdialysis studyPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Studies of excitement actions of N-methyl-D-aspartate antagonistsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Studies on the effect of opioids on the output of several neurotransmitters

Principal Investigator

Project Period (FY)

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Research Institution

[Book] 第5版 臨床歯科麻酔学2019

Irifune Masahiro 入舩正浩

IRIFUNE Masahiro 入舩正浩

入船正浩イリフネマサヒロ

入舩正浩イリフネマサヒロ

[Book] 第5版　臨床歯科麻酔学2019

[Book] 第8版　歯科麻酔学2019

[Book] 脳血管障害，歯科におけるくすりの使い方　2015-20182014

[Book] 第7版　歯科麻酔学2011

[Book] 歯科麻酔学第7版(全身麻酔薬の作用機序)2010