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KAWAHARA Michio
河原 道夫
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Alternative Names
河原 道夫 カワハラ ミチオ
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Researcher Number
30034094
External Links
Affiliation (based on the past Project Information)
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2007: Hiroshima University, Graduate School of Biomedical Sciences, Professor
2006: 広島大学, 大学院医歯薬学総合研究科, 教授
2002: Hiroshima University Graduate School of Biomedical Sciences, Dental Anesthesiology, Professor, 大学院・医歯薬学総合研究科, 教授
2001: 広島大学, 歯学部, 教授
1999: University Dental Hospital, Anesthesiology, Hiroshima University, Professor, 歯学部・附属病院, 教授
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1998: 広島大学, 歯学部・附属病院, 助手
1994: Hiroshima Univ. Dental Hosp.Prof., 歯学部・付属病院, 教授
1992 – 1994: 広島大学, 歯学部・附属病院, 教授
1989: 広島大学, 歯学部附属病院, 助教授
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Review Section/Research Field
Principal Investigator
外科・放射線系歯学
/
Surgical dentistry
Except Principal Investigator
Functional basic dentistry
/
Surgical dentistry
/
Functional basic dentistry
Keywords
Principal Investigator
ハロセン / GABA / Gabaculine / NO-711 / 肝障害 / カルシウム拮抗薬 / ベラパミ-ル / ジルチアゼム / ニカルジピン / モルモット
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/ 分離肝細胞 / 細胞内Ca^<2+>濃度 / イソフルラン / セボフルラン / 細胞内CA^<2+>濃度 / Guinea pig / Isolated hepatocytes / Intracellular Ca^<2+> concentration / Halothane / Isoflurane / Sevoflurance / 全身麻酔 / 行動薬理学 / 脳マイクロダイアリシス法 / グルタミン酸 / ケタミン / GABAculine / 全身麻酔作用 / 正向反射 / GABA神経 / 脳内GABA濃度 / 内因性GABA / General anesthesia / Behavioral pharmacology / microdialysis / Glutamate / Ketamine
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More
Except Principal Investigator
正向反射 / L-DOPA / MPP+ / SEDATI0N / BIS / DENTAL / MIDAZOLAM / SEDATION / MIDAZOLAN / NITROUS-OXIDE / GABA_A受容体 / 興奮性アミノ酸受容体 / ムシモール / ビククリン / L-アリルグリシン / NMDA / カイニン酸 / 全身麻酔薬 / 全身麻酔 / GABA神経 / プロポフォール / マイクロダイアリシス / GABAィイD2AィエD2 receptors / Excitatory amino acid receptors / Muscimol / Bicuculline / L-Allyglycine / N-methyl-D-aspartate / Kainic aci / General anesthetics / アラキドン酸 / モノアミントランスポータ / MPP^+ / インドメタシン / アスピリン / ドパミン / デシプラミン / モノアミントランスポーター / シクロオキシゲナーゼ / リドカイン / コカイン / 痙攣 / Arachidonoc acid / Monoamine transporter / Indomethacin / Ibuprofen / Dopamine / Desipramine / 全身麻酔作用 / 不動化 / 鎮痛作用 / GABA / α_2-アドレナリン受容体作動薬 / オピオイド受容体作動薬 / グリシン取り込み阻害薬 / α2-アドレナリン受容体作動薬 / 全身麻痺作用 / General Anesthesia / Behavioral pharmacology / μ-Opioid receptor agonist / α_2-Adrenergic receptor agonist / Glycine transporter inhibitor / Unconsciousness / Immobility / Analgesia
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Research Projects
(
7
results)
Research Products
(
3
results)
Co-Researchers
(
7
People)
Project Start Year (Newest)
Project Start Year (Oldest)
Clarification of mechanisms of analgesia and immobility induced by general anesthesia, and exploration of new anesthetic methods
Principal Investigator
IRIFUNE Masahiro
Project Period (FY)
2006 – 2007
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional basic dentistry
Research Institution
Hiroshima University
Bispectral Index(BIS)による精神鎮静施行時の鎮静度評価の確立
Principal Investigator
寳田 貫
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Exploratory Research
Research Field
Surgical dentistry
Research Institution
Hiroshima University
Regulation of dopamine transporter function and its role in neuronal diseases - Regulation by arachidonic acid.
Principal Investigator
DOHI Toshihiro
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Functional basic dentistry
Research Institution
HIROSHIMA UNIVERSITY
The Role of GABA and Glutamate Neurons in General Anesthetic Action
Principal Investigator
Principal Investigator
KAWAHARA Michio,
入船 正浩
Project Period (FY)
2001 – 2002
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Surgical dentistry
Research Institution
HIROSHIMA UNIVERSITY
The role of GABA neurons in general anesthesia: an in vivo microdialysis study
Principal Investigator
IRIFUNE Masahiro
Project Period (FY)
1998 – 1999
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Functional basic dentistry
Research Institution
Hiroshima University
Effects of Volatile Anesthetics on the Intracellular Ca^<2+> Concentration
Principal Investigator
Principal Investigator
KAWAHARA Michio
Project Period (FY)
1992 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
外科・放射線系歯学
Research Institution
HIROSHIMA UNIVERSITY
カルシウム拮抗薬のハロセン肝障害に及ぼす影響
Principal Investigator
Principal Investigator
河原 道夫
Project Period (FY)
1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
外科・放射線系歯学
Research Institution
Hiroshima University
All
2007
All
Journal Article
[Journal Article] MK-801 enhances gabaculine-induced loss of the righting reflex in mice, but not immobility
2007
Author(s)
Irifune, M., Katayama, S., Takarada, T., Shimizu, Y., Endo, C., Takata, T., Morita, K., Dohi, T., Sato, T., Kawahara, M
Journal Title
Can J Anaesth 54(12)
Pages
: 998-1005
Description
「研究成果報告書概要(欧文)」より
Data Source
KAKENHI-PROJECT-18592037
[Journal Article] Increased gamma-aminobutyric acid levels in mouse brain induce loss of righting reflex, but not immobility, in response to noxious stimulation
2007
Author(s)
Katayama, S., Irifune, M., Kikuchi, N., Takarada, T., Shimizu, Y., Endo, C., Takata, T., Debi, T., Sato, T., Kawahara, M
Journal Title
Anesth Analg 104(6)
Description
「研究成果報告書概要(欧文)」より
Data Source
KAKENHI-PROJECT-18592037
[Journal Article] Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice
2007
Author(s)
Irifune, M., Kikuchi, N., Saida, T., Takarada, T., Shimizu, Y., Endo, C., Morita, K., Dohi, T., Sato, T., Kawahara, M
Journal Title
Anesth Analg 104(6)
Pages
: 1415-21
Description
「研究成果報告書概要(欧文)」より
Data Source
KAKENHI-PROJECT-18592037
# of Projects (Dsc)
# of Projects (Asc)
1.
IRIFUNE Masahiro
(10176521)
# of Collaborated Projects:
4 results
# of Collaborated Products:
3 results
2.
DOHI Toshihiro
(00034182)
# of Collaborated Projects:
4 results
# of Collaborated Products:
2 results
3.
藤井 宏融
(60034021)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
4.
KINUGAWA Hiroshi
(00177883)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
5.
MORITA Katsuya
(10116684)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
6.
寳田 貫
(70274107)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
7.
北山 滋雄
(80177873)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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