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KOBATA Tetsuji  小端 哲二

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OBATA Tetsuji  小端 哲二

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Researcher Number 10205445
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2012 – 2014: 獨協医科大学, 医学部, 教授
2002 – 2005: 獨協医科大学, 医学部, 教授
1997 – 1998: 順天堂大学, 医学部, 講師
1990 – 1991: 順天堂大学, 医学部, 講師
1990: 順天堂大学, 医学部・免疫学, 講師
1989: 順天堂大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Immunology / Immunology / 膠原病・アレルギー・感染症内科学
Except Principal Investigator
Neurology / Immunology
Keywords
Principal Investigator
NF-κB2 / CD19 / TACI / BAFF-R / BLyS / BAFF / アポトーシス / FasL / Fas / 自己免疫 … More / follicular dendritic cell / germinal center / B-cell selection / チロシン・リン酸化 / 共刺激 / CD21 / NF-κB / 補助刺激 / 濾胞樹状細胞 / 胚中心 / B細胞選択 / gene therapy / bone marrow transplantation / self-tolerance / apoptosis / gld mice / autoimmunity / 遺伝子治療 / 骨髄移植 / 免疫寛容 / gldマウス / 制御性T細胞 / HIF-1α / B細胞分化 / 解糖系 / HIF-1a / ILー2R / ILー2 / T細胞活性化 / T細胞分化 / 胸腺 / 10D1 / ヒトT細胞抗原 … More
Except Principal Investigator
lymphocyte / tolerance / mAb / VLA / LFA / autoimmune disease / animal model / lipo-oligosaccharide / molecular mimicry / Guillain-Barre syndrome / 疾患モデル / リポ多糖 / Campylobacter jejuni / 症例対照試験 / Haemophilus influenzae / フィッシャー症候群 / 自己免疫疾患 / 動物モデル / リポオリゴ糖 / 分子相同性 / ギラン・バレー症候群 / CD4 / トランスフェクタント / TcR / CD2 / lympocyte Less
  • Research Projects

    (6 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (12 People)
  •  Regulatory roles of HIF-1a and glycolysis in autoimmunityPrincipal Investigator

    • Principal Investigator
      KOBATA Tetsuji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Dokkyo Medical University
  •  Synergistic effects of BAFF/BLyS and CD19 on B-cell responses in germinal centersPrincipal Investigator

    • Principal Investigator
      KOBATA Tetsuji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Dokkyo Medical University
  •  Pathogenesis of Guillain-Barre syndrome and Fisher syndromes : evidence of molecular mimicry

    • Principal Investigator
      YUKI Nobuhiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Dokkyo University School of Medicine
  •  Role of Fas/FasL interaction in self-tolerance : evaluated by bone marrow transplantationPrincipal Investigator

    • Principal Investigator
      KOBATA Tetsuji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University
  •  ヒトT細胞膜抗原10D1の胸線内T細胞分化・活性化における役割の解析Principal Investigator

    • Principal Investigator
      小端 哲二
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University
  •  Immuno-Melecular characterization of lymphocyte functioning antigen (LFA)

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Juntendo University School of Medicine

All 2014 2013 2005 Other

All Journal Article Presentation Book

  • [Book] サイトカイン・増殖因子 用語ライブラリー(菅村和夫, 宮園浩平, 宮澤恵二, 田中伸幸 編)2005

    • Author(s)
      小端 哲二(分担執筆)
    • Publisher
      APRIL, BAFF/Blys
    • Data Source
      KAKENHI-PROJECT-16590410
  • [Book] サイトカニン・増殖因子 用語ライブラリー(菅村和夫、宮園浩平、宮澤恵ニ、田中伸幸編)2005

    • Author(s)
      小端 哲二
    • Publisher
      羊土社(分担執筆)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16590410
  • [Journal Article] CD2-mediated regulation of peripheral CD4+CD25+ regulatory T cell apoptosis accompanied with down regulation of Bim2013

    • Author(s)
      Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H.
    • Journal Title

      Immunology

      Volume: 139 Issue: 1 Pages: 48-60

    • DOI

      10.1111/imm.12054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Cellular metabolism of CD4+ CD25+ regulatory T cells is distinct from that of CD4+ CD25- conventional T cells2014

    • Author(s)
      Kojima H, Kanno Y, Kashiwakura Y, Hashiguchi M, Kobata T
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Glycolysis, that impacts on bone marrow B cell development, dose not have a decisive influence on peripheral B cell differentiation2014

    • Author(s)
      Kanno Y, Kashiwakura T, Hashiguchi M, Kobata T, Kojima H
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] CD2 stimulation upregulates Foxp3 in murine peripheral regulatory T cells2014

    • Author(s)
      Kashiwakura Y, Kanno Y, Hashiguchi M, Kobata T, Kojima H
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-12
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] CD2-mediated regulation of peripheral CD4+CD25+ regulatory T cell apoptosis accompanied by down regulation of Bim2013

    • Author(s)
      Kashiwakura Y, Sakurai D., Kanno Y, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] HIF-1α is regulated by IL-7 in pro-B cells during B cell development.2013

    • Author(s)
      Kanno Y, Kashiwakura T, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Cytokine-dependent CD4+CD25+ regulatory T cell activation during immune responses2013

    • Author(s)
      Kojima H, Kanno Y, Kashiwakura Y, Hashiguchi M, Kobata T.
    • Organizer
      第42回日本免疫学会学術集会
    • Place of Presentation
      千葉市
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] TCR-independent CD4+CD25+ regulatory T cell activation during immune responses2013

    • Author(s)
      Kojima H, Kashiwakura Y, Hashiguchi M, Kobata T.
    • Organizer
      15th international Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] CD2-mediated regulation of peripheral CD4+CD25+ regulatory T cell apoptosis accompanied by downregulation of Bim2013

    • Author(s)
      Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, Tokudome S, Kobata T, Kojima H.
    • Organizer
      15th international Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] IL-7 is a principal factor for HIF-1α regulated pro-B development

    • Author(s)
      Kanno Y, Kashiwakura T, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Characterization of activated CD4+ CD25+ regulatory T cells during immune responses

    • Author(s)
      Kojima H, Kanno Y, Kashiwakura Y, Hashiguchi M, Kobata T.
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-24591454
  • [Presentation] Peripheral CD4+ CD25+ regulatory T cell survival is regulated by a combination of CD2 stimuli and the interaction with stromal cells

    • Author(s)
      Kashiwakura Y, Kanno Y, Hashiguchi M, Kobata T, Kojima H.
    • Organizer
      第41回日本免疫学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-24591454
  • 1.  OKUMURA Ko (50009700)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  YAGITA Hideo (30182306)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  HASHIGUCHI Masaaki (20372443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 4.  KASHIWAKURA Yuji (40382890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 5.  NISHIOKA Kusuki (60049070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YUKI Nobuhiro (60285913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YAMADA Mitsunori (30240039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  UEDA Syuichi (60150570)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KOJIMA Hidefumi (40322408)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  SAKURAI Daisuke (30382964)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  屋部 登志雄 (50239836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  中村 哲也 (30189047)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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