Kosako Hidetaka 小迫英尊

… Alternative Names

KOSAKO Hidetaka 小迫英尊

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Researcher Number	10291171
Other IDs
Affiliation (Current)	2025: 徳島大学, 先端酵素学研究所, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 徳島大学, 先端酵素学研究所, 教授 2016 – 2020: 徳島大学, 先端酵素学研究所(オープンイノベ), 教授 2016: 徳島大学, 先端酵素学研究所, 教授 2015 – 2016: 徳島大学, 藤井節朗記念医科学センター, 教授 2013 – 2015: 徳島大学, 藤井節郎記念医科学センター, 教授 … More 2014: 徳島大学, 学内共同利用施設等, 教授 2014: 徳島大学, 疾患酵素学研究センター, 教授 2013: 徳島大学, 藤井節郎記念医科学センター, 特任教授 2007 – 2013: The University of Tokushima, 疾患酵素学研究センター, 准教授 2007: 東京大学, 医科学研究所, 寄付研究部門教員(常勤形態) 2006: 東京大学, 医科学研究所, 寄付部門教員(常勤形態) 2004 – 2006: 東京大学, 医科学研究所, 寄付研究部門教員 2005: 東京大学, 医科学研究所, 寄付研究部門教員(常勤形態) 2002: The Institute of Medical Science, The University of Tokyo, research associate, 医科学研究所, 助手 2000 – 2001: 東京大学, 大学院・医学系研究科, 助手 1997 – 1999: 愛知県がんセンター, 生化学部, 研究員 Less
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 44010:Cell biology-related / Biological Sciences / Complex systems / General medical chemistry / Biological Sciences / Cell biology / Functional biochemistry Except Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Medium-sized Section 49:Pathology, infection/immunology, and related fields … More / Structural biochemistry / Biological Sciences / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 49040:Parasitology-related / Basic Section 49030:Experimental pathology-related / Basic Section 55020:Digestive surgery-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 53020:Cardiology-related / Neurochemistry/Neuropharmacology / Immunology / Human pathology / Pathological medical chemistry Less
Keywords	Principal Investigator リン酸化 / プロテオーム / MAPキナーゼ / シグナル伝達 / 核膜孔複合体 / プロテオミクス / 抗リン酸化抗体 / ヌクレオポリン / 2D-DIGE / PINK1 … More / ERK / IMAC / nanobody / 自然免疫 / STING / ミトコンドリア / オートファジー / Parkin / IP-MS / TMT / 質量分析 / パーキンソン病 / キナーゼ / タンパク質間相互作用 / FGリピート / 輸送運搬体 / 核-細胞質間輸送 / 細胞運動 / ダイニン / 二次元電気泳動 / 質量分析計 / 網羅的解析 / 分裂溝 / CFキナーゼ / 中間径フィラメント / 細胞質分裂 / ACBD3 / BAR / APEX / 近接ビオチン標識 / オルガネラ間輸送 / ユビキチン化 / 絶対定量 / 免疫沈降 / 近接ビオチン標識法 / AQUA / TBK1 / インタラクトーム / GFP-Trap / Tamavidin / ビオチン / BioID / Phos-tag / LC-MS/MS / 相互作用 / PRM / ROCK / T細胞 / ユビキチン / PKD / 核ー細胞質間輸送 / 核－細胞質間輸送 / がん化 / 糸球体 / 細胞間接着 / 細胞接着 / 細胞内情報伝達 / 核輸送因子 / セミインタクト細胞 / siRNA / PHドメイン / プロテアソーム / プロテインキナーゼ / タンパク質キナーゼ / 細胞質ダイニン / リン酸化モチーフ抗体 / EPLIN / アクチン架橋タンパク質 / 核内輸送 / 核膜孔 / インスリン / Akt / ミオシン軽鎖 / Y-27632 / Rho-キナーゼ / Rhoキナーゼ / Rho-キナ-ゼ … More Except Principal Investigator プロテオミクス / リン酸化 / 患者由来がんモデル / 炎症 / T細胞 / 質量分析 / 翻訳後修飾 / 蛋白質 / 分析科学 / シグナル伝達 / バイオテクノロジー / プロテオーム / タンパク質 / 転写因子 / 疾患インタラクトーム / ヒトタンパク質アレイ / タンパク質アレイ / 疾患インララクトーム / 自己炎症疾患 / 相互作用ダイナミクス / 薬剤応答 / 近位依存性ビオチン標識 / インタラクトーム / EGFR / ポリマー物理 / 細胞内非膜オルガネラ / 非膜オルガネラ / 液-液相分離 / 核小体 / 細胞周期制御 / タンパク質翻訳後修飾 / 液ー液相分離 / ゲノム編集 / 赤血球侵入 / マラリア原虫 / マラリア / バイオマーカー / 感受性試験 / プロテオーム解析 / トラベクテジン / 肉腫 / 糖鎖 / 薬剤感受性試験 / プロテオゲノミクス / 腹膜偽粘液腫 / proteogenomics / patient-derived model / pseudomyxoma peritonei / 自己免疫疾患 / がん / 免疫補助受容体 / 免疫学 / 線維化 / 筋線維芽細胞 / リン酸化プロテオミクス / 遺伝子発現解析 / リン酸化プロテオーム解析 / ChIPseq解析 / リン酸化プロテオーム / IL-21 / Th17細胞 / アリルハイドロカーボン受容体 / 肺動脈性肺高血圧症 / 肺高血圧症 / 自然免疫 / 細菌感染 / 生理活性脂質 / サイトカイン / 感染症 / 免疫 / homeodomain factor / bHLH factor / glia / neuron / neural stem cell / transcription factor / neural development / ホメオドメイン型転写因子 / bHLH因子 / グリア / ニューロン / 神経幹細胞 / 神経発生 / 免疫シグナル伝達 / ヒストン脱メチル化 / IL-4 / ヘルパーT細胞 / カルシウム / シグナル情報伝達 / T細胞分化 / 癌幹細胞 / 微小環境 / 癌進展 / 乳癌 / オルガネラ / 巨大分子複合体 / 2次元ゲル電気泳動 / LC-MS / チロシンリン酸 / p38MAPキナーゼ / ERK / リン酸化タンパク質 / 二次元ゲル電気泳動 Less

The mechanism of erythrocyte invasion by malaria parasites through proteomics of secretory organelles
- Principal Investigator
  
  新澤直明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of the protein-protein interaction dynamics of EGFR on the plasma membrane using proximity biotinylation enzyme
- Principal Investigator
  
  澤崎達也
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Ehime University
Structural and functional regulation of intracellular membrane-less organelles by post-translational modifications.
- Principal Investigator
  
  吉村成弘
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University
先端プロテオミクス技術の開発による自然免疫シグナルの新規制御機構の解明Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokushima
Comprehensive disease-associated interactome and model mice elucidate diversity and periodicity of the autoinflammatory disease
- Principal Investigator
  
  増本純也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Ehime University
Regulation of immunological synapse by co-receptors
- Principal Investigator
  
  岡崎拓
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  The University of Tokyo
肉腫におけるトラベクテジンの奏効性と融合遺伝子の相関の分子背景を調べる研究
- Principal Investigator
  
  近藤格
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  National Cancer Center Japan
Development of a new treatment for pseudomyxoma peritoneum using proteogenomic analysis and patient-derived models
- Principal Investigator
  
  Noguchi Rei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  National Cancer Center Japan
The Pathogenesis of pulmonary arterial hypertension via aryl hydrocarbon receptor
- Principal Investigator
  
  Nakaoka Yoshikazu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  National Cardiovascular Center Research Institute
Global proteomic analysis of the PINK1-Parkin pathway and elucidation of mitochondrial regulationPrincipal Investigator
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  The University of Tokushima
Functional analysis of fibrosis-promoting molecules specifically expressed in myofibroblasts and laying the foundations for their drug discovery applications.
- Principal Investigator
  
  Michio Nakaya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kyushu University
自然免疫分子STINGを介したシグナル伝達経路の重層的プロテオーム解析Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokushima
Understanding of innate immune system-mediated inflammatory response regulated by bioactive lipids
- Principal Investigator
  
  saitoh tatsuya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Osaka University
Advanced proteomic analysis of signaling pathays mediated by Parkinson's disease-associated kinase PINK1Principal Investigator
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokushima
Elucidation of molecular mechanisms of the selection and maturation of thymocytes
- Principal Investigator
  
  Oh-hora Masatsugu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Kyushu University
Identification and functional analysis of substrates of disease-associated protein kinases using multiple phosphoproteomic technologiesPrincipal Investigator
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokushima
プロテオミクスを用いたＦＧヌクレオポリンのリン酸化による核膜孔制御の解明Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Proteomics and immunohistochemical analyses of phosphorylation signaling in the tumor microenvironments for breast cancer progression
- Principal Investigator
  
  YOSHIDA Tosimitchi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Mie University
Analysis of regulatory mechanisms of newly identified ERK substratesPrincipal Investigator
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokushima
シグナル伝達キナーゼによるリン酸化を介したFGヌクレオポリンの機能制御機構の解明Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Global analysis of post-translational modifications in super-molecular protein complexes by targeted proteomics
- Principal Investigator
  
  TANIGUCHI Hisaaki
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokushima
Global identification and functional analysis of protein kinase substrates by a phosphoproteomic approachPrincipal Investigator
- Principal Investigator
  
  KOSAKO Hidetaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokushima
Proteomic analysis of EGF receptor-mediated signaling
- Principal Investigator
  
  TANIGUCHI Hisaaki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokushima
イレッサ感受性診断プロテインチップの創製
- Principal Investigator
  
  谷口寿章
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokushima
リン酸化プロテオーム解析による腫瘍特異的転写制御機構の解明
- Principal Investigator
  
  服部成介
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
新たなリン酸化プロテオミクスによるMAPキナーゼ経路の標的因子の網羅的解析Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokushima
  The University of Tokyo
リン酸化プロテオーム解析による腫瘍特異的転写制御機構の解明
- Principal Investigator
  
  服部成介
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
リン酸化プロテオームによるインスリン/Akt経路の標的因子の網羅的解析法の開発Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
リン酸化プロテオーム解析によるERK及びROCKの基質の網羅的同定と機能解析Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
Molecular control mechanisms of multipotential neural stem cells
- Principal Investigator
  
  NAKAFUKU Masato
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
Rho/Rho-キナーゼ経路による中間径フィラメント構築の制御機構の解明Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
  Aichi Cancer Center Research Institute
抗リン酸化抗体の利用による、細胞質分裂期に分裂溝近傍で活性化するキナーゼの同定Principal Investigator
- Principal Investigator
  
  小迫英尊
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Aichi Cancer Center Research Institute

[Book] タンパク質の事典(分担執筆、猪飼篤ら編)2008
- Author(s)
  小迫英尊、後藤由季子
- Total Pages
  863
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20570177
[Book] タンパク質の事典(分担執筆、猪飼篤ら, 編)2008
- Author(s)
  小迫英尊, 他
- Total Pages
  863
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20570177
[Book] タンパク質のリン酸化(タンパク質の事典)(猪飼篤、伏見譲編)2007
- Author(s)
  小迫英尊, 後藤由希子
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-18770166
[Journal Article] CANE, a component of the NLRP3 inflammasome, promotes inflammasome activation2024
- Author(s)
  Kaneko Naoe、Kurata Mie、Yamamoto Toshihiro、Sakamoto Akimasa、Takada Yasutsugu、Kosako Hidetaka、Takeda Hiroyuki、Sawasaki Tatsuya、Masumoto Junya
- Journal Title
  
  Journal of Immunology
  
  Volume: 213 Issue: 1 Pages: 1-10
- DOI
  10.4049/jimmunol.2300175
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19438, KAKENHI-PROJECT-23K27635, KAKENHI-PROJECT-23H05323
[Journal Article] Host ZCCHC3 blocks HIV-1 infection and production through a dual mechanism2024
- Author(s)
  Yi Binbin、Tanaka Yuri L.、Cornish Daphne、Kosako Hidetaka、Butlertanaka Erika P.、Sengupta Prabuddha、Lippincott-Schwartz Jennifer、Hultquist Judd F.、Saito Akatsuki、Yoshimura Shige H.
- Journal Title
  
  iScience
  
  Volume: 27 Issue: 3 Pages: 109107-109107
- DOI
  10.1016/j.isci.2024.109107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00369
[Journal Article] ALLO-1- and IKKE-1-dependent positive feedback mechanism promotes the initiation of paternal mitochondrial autophagy2024
- Author(s)
  Sasaki Taeko、Kushida Yasuharu、Norizuki Takuya、Kosako Hidetaka、Sato Ken、Sato Miyuki
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 1460-1460
- DOI
  10.1038/s41467-024-45863-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15097, KAKENHI-PROJECT-22KJ0444, KAKENHI-PROJECT-20K06628, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K21307, KAKENHI-PROJECT-23K27171
[Journal Article] In vivo CRISPR screening directly targeting testicular cells2024
- Author(s)
  Noguchi Yuki、Onodera Yasuhito、Miyamoto Tatsuo、Maruoka Masahiro、Kosako Hidetaka、Suzuki Jun
- Journal Title
  
  Cell Genomics
  
  Volume: 4 Issue: 3 Pages: 100510-100510
- DOI
  10.1016/j.xgen.2024.100510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-22K20972, KAKENHI-PROJECT-21H02718, KAKENHI-PROJECT-23K27171
[Journal Article] HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence2024
- Author(s)
  1.Cui, M., Yamano, K., Yamamoto, K., Yamamoto-Imoto, H., Minami, S., Yamamoto, T., Matsui, S., Kaminishi, T., Shima, T., Ogura, M., Tsuchiya, M., Nishino, K., Layden B., Kato, H., Ogawa, H., Oki, S., Okada, Y., Isaka, Y., Kosako, H., Matsuda, N., *Yoshimori, T., *Nakamura, S.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 2
- DOI
  10.1073/pnas.2306454120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18140, KAKENHI-PROJECT-22KJ2105, KAKENHI-PROJECT-22K06082, KAKENHI-PROJECT-20K06628, KAKENHI-PLANNED-19H05712, KAKENHI-PLANNED-23H04923, KAKENHI-ORGANIZER-21H05144, KAKENHI-PLANNED-21H05145, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21H02428, KAKENHI-PROJECT-21H02935, KAKENHI-PROJECT-23K23841
[Journal Article] TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria2023
- Author(s)
  Shiori Akabane, Kiyona Watanabe, Hidetaka Kosako, Shun-ichi Yamashita, Kohei Nishino, Masahiro Kato, Shiori Sekine, Tomotake Kanki, Noriyuki Matsuda, Toshiya Endo, Toshihiko Oka
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 5 Pages: 112454-112454
- DOI
  10.1016/j.celrep.2023.112454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03257, KAKENHI-PROJECT-22K15107, KAKENHI-PROJECT-20K06628, KAKENHI-PLANNED-20H05929, KAKENHI-PROJECT-20H05689, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23878, KAKENHI-PROJECT-23K27171
[Journal Article] Extracellular calcium functions as a molecular glue for transmembrane helices to activate the scramblase Xkr42023
- Author(s)
  Zhang Panpan、Maruoka Masahiro、Suzuki Ryo、Katani Hikaru、Dou Yu、Packwood Daniel M.、Kosako Hidetaka、Tanaka Motomu、Suzuki Jun
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 5592-5592
- DOI
  10.1038/s41467-023-40934-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-23K27171
[Journal Article] VGLL3 is a mechanosensitive protein that promotes cardiac fibrosis through liquid-liquid phase separation2023
- Author(s)
  Horii Yuma、Matsuda Shoichi、Toyota Chikashi、Morinaga Takumi、Nakaya Takeo、Tsuchiya Soken、Ohmuraya Masaki、Hironaka Takanori、Yoshiki Ryo、Kasai Kotaro、Yamauchi Yuto、Takizawa Noburo、Nagasaka Akiomi、Tanaka Akira、Kosako Hidetaka、Nakaya Michio
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-19
- DOI
  10.1038/s41467-023-36189-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-22K06629, KAKENHI-PROJECT-22K07997, KAKENHI-PROJECT-20H03383, KAKENHI-PROJECT-21J11273, KAKENHI-PROJECT-22KJ2466, KAKENHI-PROJECT-22KJ2468
[Journal Article] Proximity extracellular protein-protein interaction analysis of EGFR using AirID-conjugated fragment of antigen binding2023
- Author(s)
  Yamada Kohdai、Shioya Ryouhei、Nishino Kohei、Furihata Hirotake、Hijikata Atsushi、Kaneko Mika K.、Kato Yukinari、Shirai Tsuyoshi、Kosako Hidetaka、Sawasaki Tatsuya
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 8301-8301
- DOI
  10.1038/s41467-023-43931-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-23K21721, KAKENHI-PROJECT-23K27171
[Journal Article] Integrating analysis of proteome profile and drug screening identifies therapeutic potential of MET pathway for the treatment of malignant peripheral nerve sheath tumor2023
- Author(s)
  Tsuchiya Ryuto、Yoshimatsu Yuki、Noguchi Rei、Sin Yooksil、Ono Takuya、Akiyama Taro、Kosako Hidetaka、Yoshida Akihiko、Ohtori Seiji、Kawai Akira、Kondo Tadashi
- Journal Title
  
  Expert Review of Proteomics
  
  Volume: 20 Issue: 4-6 Pages: 109-119
- DOI
  10.1080/14789450.2023.2218035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07036, KAKENHI-PROJECT-21H03062
[Journal Article] Proteomic analysis of spheroids of rhabdomyosarcoma cells cultured with decellularized muscle extracts2022
- Author(s)
  Sin Yooksil、Ono Takuya、Tsuchiya Ryuto、Noguchi Rei、Yoshimatsu Yuki、Kosako Hidetaka、Kondo Tadashi
- Journal Title
  
  J. Electrophor
  
  Volume: 66 Issue: 1 Pages: 1-4
- DOI
  10.2198/jelectroph.66.1
- ISSN
  1349-9394, 1349-9408
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07036, KAKENHI-PROJECT-21K16669
[Journal Article] Optimized Workflow for Enrichment and Identification of Biotinylated Peptides Using Tamavidin 2-REV for BioID and Cell Surface Proteomics2022
- Author(s)
  Nishino Kohei、Yoshikawa Harunori、Motani Kou、Kosako Hidetaka
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 21 Issue: 9 Pages: 2094-2103
- DOI
  10.1021/acs.jproteome.2c00130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-20K07340, KAKENHI-PROJECT-21K06138
[Journal Article] Identification and validation of new ERK substrates by phosphoproteomic technologies including Phos-tag SDS-PAGE2022
- Author(s)
  Yoshikawa Harunori、Nishino Kohei、Kosako Hidetaka
- Journal Title
  
  Journal of Proteomics
  
  Volume: 258 Pages: 104543-104543
- DOI
  10.1016/j.jprot.2022.104543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-21K06138
[Journal Article] Cell cycle-specific phase separation regulated by protein charge blockiness2022
- Author(s)
  Yamazaki H、Takagi M、Kosako H、Hirano T、Yoshimura SH.
- Journal Title
  
  Nature Cell Biology
  
  Volume: - Issue: 5 Pages: 625-632
- DOI
  10.1038/s41556-022-00903-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15039, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-20K06649, KAKENHI-PLANNED-20H05938, KAKENHI-PROJECT-18H05276
[Journal Article] The Golgi-resident protein ACBD3 concentrates STING at ER-Golgi contact sites to drive export from the ER2022
- Author(s)
  Motani Kou、Saito-Tarashima Noriko、Nishino Kohei、Yamauchi Shunya、Minakawa Noriaki、Kosako Hidetaka
- Journal Title
  
  Cell Reports
  
  Volume: 41 Issue: 12 Pages: 111868-111868
- DOI
  10.1016/j.celrep.2022.111868
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-20K07340, KAKENHI-PROJECT-21H02606, KAKENHI-PROJECT-21K19052
[Journal Article] Binding of LAG-3 to stable peptide-MHC class II limits T?cell function and suppresses autoimmunity and anti-cancer immunity2022
- Author(s)
  Maruhashi Takumi、Sugiura Daisuke、Okazaki Il-mi、Shimizu Kenji、Maeda Takeo K.、Ikubo Jun、Yoshikawa Harunori、Maenaka Katsumi、Ishimaru Naozumi、Kosako Hidetaka、Takemoto Tatsuya、Okazaki Taku
- Journal Title
  
  Immunity
  
  Volume: - Issue: 5 Pages: 912-924
- DOI
  10.1016/j.immuni.2022.03.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05417, KAKENHI-PROJECT-19H01029, KAKENHI-PROJECT-19H03423, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-21K07076, KAKENHI-PROJECT-19H01070, KAKENHI-PROJECT-21K19270, KAKENHI-PROJECT-21K19605, KAKENHI-PLANNED-18H05415, KAKENHI-PROJECT-21K06526
[Journal Article] A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues2022
- Author(s)
  Yamanaka Satoshi、Horiuchi Yuto、Matsuoka Saya、Kido Kohki、Nishino Kohei、Maeno Mayaka、Shibata Norio、Kosako Hidetaka、Sawasaki Tatsuya
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 183-183
- DOI
  10.1038/s41467-021-27818-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00285, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H02951, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-21K19230, KAKENHI-PROJECT-21K15076
[Journal Article] Identification of an endoplasmic reticulum proteostasis modulator that enhances insulin production in pancreatic β cells2022
- Author(s)
  Miyake Masato、Sobajima Mitsuaki、Kurahashi Kiyoe、Shigenaga Akira、Denda Masaya、Otaka Akira、Saio Tomohide、Sakane Naoki、Kosako Hidetaka、Oyadomari Seiichi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 7 Issue: 6 Pages: 996-1009
- DOI
  10.1016/j.chembiol.2022.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02853, KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-22K15253, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20K08909
[Journal Article] The ubiquitination-deubiquitination cycle on the ribosomal protein eS7A is crucial for efficient translation2021
- Author(s)
  Takehara Yuka、Yashiroda Hideki、Matsuo Yoshitaka、Zhao Xian、Kamigaki Akane、Matsuzaki Tetsuo、Kosako Hidetaka、Inada Toshifumi、Murata Shigeo
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 3 Pages: 102145-102145
- DOI
  10.1016/j.isci.2021.102145
- NAID
  120007182109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06481, KAKENHI-PROJECT-20K06628, KAKENHI-PUBLICLY-19H04966, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022
[Journal Article] Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy2021
- Author(s)
  Kojima W, Yamano K, Kosako H, Imai K, Kikuchi R, Tanaka K, Matsuda N
- Journal Title
  
  Autophagy
  
  Volume: - Issue: 8 Pages: 1-26
- DOI
  10.1080/15548627.2021.1874133
- NAID
  120007174412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-20K06628, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18H02443, KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712
[Journal Article] Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane2021
- Author(s)
  Masahiro Maruoka, Panpan Zhang, Hiromi Mori, Eiichi Imanishi, Daniel M Packwood, Hiroshi Harada, Hidetaka Kosako, Jun Suzuki
- Journal Title
  
  Mol Cell
  
  Volume: 81 (7) Issue: 7 Pages: 1397-1410
- DOI
  10.1016/j.molcel.2021.02.025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06486, KAKENHI-PROJECT-20K06628
[Journal Article] BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)2020
- Author(s)
  Motani Kou、Kosako Hidetaka
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 32 Pages: 11174-11183
- DOI
  10.1074/jbc.ra120.014323
- NAID
  120007132263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06628, KAKENHI-PROJECT-20K07340, KAKENHI-PUBLICLY-19H04966
[Journal Article] AirID, a novel proximity biotinylation enzyme, for analysis of protein-protein interactions2020
- Author(s)
  Kido K, Yamanaka S, Nakano S, Motani K, Shinohara S, Nozawa A, Kosako H, Ito S and Sawasaki T
- Journal Title
  
  Elife
  
  Volume: 9
- DOI
  10.7554/elife.54983
- NAID
  120007125057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07340, KAKENHI-PLANNED-16H06579, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H02951
[Journal Article] Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure2019
- Author(s)
  Sakuragi T, Kosako H, Nagata S
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 116 Issue: 8 Pages: 2907-2912
- DOI
  10.1073/pnas.1820499116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18KK0229, KAKENHI-PROJECT-15H05785
[Journal Article] Phosphoproteomic identification and functional characterization of protein kinase substrates by 2D-DIGE and Phos-tag PAGE2019
- Author(s)
  Motani K, Kosako H
- Journal Title
  
  Biochim Biophys Acta Proteins Proteomics
  
  Volume: 1867 Issue: 1 Pages: 57-61
- DOI
  10.1016/j.bbapap.2018.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-17K08661, KAKENHI-PROJECT-18KK0229
[Journal Article] Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region2019
- Author(s)
  Yoshinaka Takahiro、Kosako Hidetaka、Yoshizumi Takuma、Furukawa Ryo、Hirano Yu、Kuge Osamu、Tamada Taro、Koshiba Takumi
- Journal Title
  
  iScience
  
  Volume: 19 Pages: 1065-1078
- DOI
  10.1016/j.isci.2019.08.056
- NAID
  120006959760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04863, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-17H03667
[Journal Article] Mass spectrometry-based methods for analysing the mitochondrial interactome in mammalian cells2019
- Author(s)
  Koshiba Takumi、Kosako Hidetaka
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 167 Issue: 3 Pages: 225-231
- DOI
  10.1093/jb/mvz090
- NAID
  120006959753
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PUBLICLY-18H04863, KAKENHI-PUBLICLY-19H04966, KAKENHI-PROJECT-17H03667
[Journal Article] Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes2019
- Author(s)
  Koyano Fumika、Yamano Koji、Kosako Hidetaka、Kimura Yoko、Kimura Mayumi、Fujiki Yukio、Tanaka Keiji、Matsuda Noriyuki
- Journal Title
  
  EMBO reports
  
  Volume: 20 Issue: 12
- DOI
  10.15252/embr.201947728
- NAID
  120006942558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-17H03675, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18H02443
[Journal Article] Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL2019
- Author(s)
  Koyano Fumika、Yamano Koji、Kosako Hidetaka、Tanaka Keiji、Matsuda Noriyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 26 Pages: 10300-10314
- DOI
  10.1074/jbc.ra118.006302
- NAID
  120006959752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-18H02443
[Journal Article] The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans.2018
- Author(s)
  M. Sato, K. Sato, K. Tomura, H. Kosako and K. Sato
- Journal Title
  
  Nature Cell Biology
  
  Volume: 20 Issue: 1 Pages: 81-91
- DOI
  10.1038/s41556-017-0008-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PUBLICLY-16H01191, KAKENHI-PROJECT-17H03669
[Journal Article] Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumour microenvironment.2018
- Author(s)
  Terabayashi T., Hanada K., Motani K., Kosako H., Yamaoka M., Kimura T. and Ishizaki T.
- Journal Title
  
  Genes to Cells
  
  Volume: 印刷中 Issue: 6 Pages: 466-479
- DOI
  10.1111/gtc.12584
- NAID
  130007811814
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07119, KAKENHI-PROJECT-17K08339, KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-17K09838, KAKENHI-PROJECT-18K16239
[Journal Article] Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.2018
- Author(s)
  Motani, K.*, and Kosako, H.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 印刷中 Issue: 20 Pages: 7717-7726
- DOI
  10.1074/jbc.ra118.002175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08661, KAKENHI-PROJECT-15K19024, KAKENHI-PROJECT-17K08635
[Journal Article] Global Identification of ERK Substrates by Phosphoproteomics Based on IMAC and 2D-DIGE.2017
- Author(s)
  H. Kosako, K. Motani.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1487 Pages: 137-149
- DOI
  10.1007/978-1-4939-6424-6_10
- ISBN
  9781493964222, 9781493964246
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15K19024
[Journal Article] Functional analysis of disease-associated protein kinases using phosphoproteomic technologies including Phos-tag2017
- Author(s)
  小迫英尊, 茂谷康
- Journal Title
  
  Electrophoresis Letters
  
  Volume: 61 Issue: 2 Pages: 53-57
- DOI
  10.2198/electroph.61.53
- NAID
  130006207358
- ISSN
  2189-2628, 2189-2636
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08635
[Journal Article] PKA regulates PINK1 stability and Parkin recruitment to damaged mitochondria through phosphorylation of MIC60.2016
- Author(s)
  S. Akabane, M. Uno, N. Tani, S. Shimazaki, N. Ebara, H. Kato, H. Kosako, and T. Oka.
- Journal Title
  
  Molecular Cell
  
  Volume: 62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26440101
[Journal Article] Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-12016
- Author(s)
  Ishikawa E, Kosako H, Yasuda T, Ohmuraya M, Araki K, Kurosaki T, Saito T, Yamasaki S
- Journal Title
  
  Nat Commun
  
  Volume: 7 Issue: 1 Pages: 12756-12756
- DOI
  10.1038/ncomms12756
- NAID
  120006535062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K08841, KAKENHI-PROJECT-16K09398, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16H06276
[Journal Article] Analog-to-digital Conversion in the Cellular Signaling System2016
- Author(s)
  新土優樹，小迫英尊，佐甲靖志，高橋恒一
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 56 Issue: 6 Pages: 334-336
- DOI
  10.2142/biophys.56.334
- NAID
  130005170660
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J03140, KAKENHI-PROJECT-26440101
[Journal Article] Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.2016
- Author(s)
  Y. Shindo, K. Iwamoto, K. Mouri, K. Hibino, M. Tomita, H. Kosako, Y. Sako and K. Takahashi.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 10485-10485
- DOI
  10.1038/ncomms10485
- NAID
  120006535049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15H02394, KAKENHI-PROJECT-14J03140
[Journal Article] Phosphorylated ubiquitin chain is the genuine Parkin receptor.2015
- Author(s)
  K. Okatsu, F. Koyano, M. Kimura, H. Kosako, Y. Saeki, K. Tanaka and N. Matsuda
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 209 Issue: 1 Pages: 111-128
- DOI
  10.1083/jcb.201410050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
[Journal Article] プロテオミクスで明らかになった核膜孔複合体の翻訳後修飾による機能制御2015
- Author(s)
  小迫英尊
- Journal Title
  
  生化学
  
  Volume: 87 Pages: 49-55
- Data Source
  KAKENHI-PUBLICLY-24113717
[Journal Article] Ubiquitin is phosphorylated by PINK1 to activate parkin.2014
- Author(s)
  Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., Kimura, Y., Tsuchiya, H., Yoshihara, H., Hirokawa, T., Endo, T., Fon. E. A., Trempe, J. F., Saeki, Y., Tanaka, K., and Matsuda, N.
- Journal Title
  
  Nature
  
  Volume: 510(in press) Issue: 7503 Pages: 162-166
- DOI
  10.1038/nature13392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570231, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657072, KAKENHI-PUBLICLY-25112522, KAKENHI-PROJECT-25870311, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26440070, KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-22227003
[Journal Article] Epithelial protein lost in neoplasm modulates platelet-derived growth factor-mediated adhesion and motility of mesangial cells2014
- Author(s)
  Haruko Tsurumi, et. al
- Journal Title
  
  Kidney International
  
  Volume: Epub Issue: 3 Pages: 548-557
- DOI
  10.1038/ki.2014.85
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J11068, KAKENHI-PROJECT-13J06109, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23591586, KAKENHI-PROJECT-24390259, KAKENHI-PROJECT-24591214, KAKENHI-PROJECT-24591569, KAKENHI-PROJECT-25461617, KAKENHI-PROJECT-25870536, KAKENHI-PROJECT-26440101
[Journal Article] Parkin catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation2013
- Author(s)
  Masahiro Iguchi, Yuki Kujuro, Kei Okatsu, Fumika Koyano, Hidetaka Kosako, Mayumi Kimura, Norihiro Suzuki, Shinichiro Uchiyama, Keiji Tanaka, Noriyuki Matsuda
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288 Issue: 30 Pages: 22019-32
- DOI
  10.1074/jbc.m113.467530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23687018, KAKENHI-PUBLICLY-24111557, KAKENHI-PUBLICLY-25112522, KAKENHI-PROJECT-25860721
[Journal Article] GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance2013
- Author(s)
  Nakaya M, Kosako H, Taniguchi H, Sato Kurose H
- Journal Title
  
  Nat Commun.
  
  Pages: 153-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370042
[Journal Article] PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria2012
- Author(s)
  尾勝圭
- Journal Title
  
  Nature Communications
  
  Volume: 3 Issue: 1 Pages: 1016-1016
- DOI
  10.1038/ncomms2016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06061, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-22370042, KAKENHI-PROJECT-22370071, KAKENHI-PROJECT-23570231, KAKENHI-PROJECT-23570232, KAKENHI-PROJECT-23687018, KAKENHI-PROJECT-24657138, KAKENHI-PROJECT-24790896, KAKENHI-PLANNED-23111003, KAKENHI-PUBLICLY-23129506, KAKENHI-PUBLICLY-24111557, KAKENHI-PUBLICLY-24113717
[Journal Article] リン酸化プロテオミクスによるキナーゼ基質の大規模解析2011
- Author(s)
  小迫英尊
- Journal Title
  
  生化学
  
  Volume: 83 Pages: 1122-1127
- NAID
  10030345967
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113514
[Journal Article] Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways2011
- Author(s)
  H.Kosako, et al.
- Journal Title
  
  Expert Review of Proteomics
  
  Volume: 8 Pages: 81-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways.2011
- Author(s)
  H.Kosako, et al.
- Journal Title
  
  Expert Review of Proteomics
  
  Volume: 8 Pages: 81-94
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113514
[Journal Article] Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways.2011
- Author(s)
  Kosako, H., Nagano, K.
- Journal Title
  
  Expert Rev. Proteomics 8
  
  Pages: 81-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] リン酸化プロテオミクスによるキナーゼ基質の大規模解析2011
- Author(s)
  小迫　英尊
- Journal Title
  
  生化学
  
  Volume: 83 Pages: 1122-1127
- NAID
  10030345967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570231
[Journal Article] リン酸化プロテオミクスで明らかとなったERKによる核膜孔複合体の機能制御2010
- Author(s)
  小迫英尊
- Journal Title
  
  実験医学 28
  
  Pages: 69-73
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phosphorylation of nucleoporins : signal transduction-mediated regulation of their interaction with nuclear transport receptors.2010
- Author(s)
  H.Kosako, et al.
- Journal Title
  
  Nucleus
  
  Volume: 1 Pages: 309-313
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113514
[Journal Article] Phosphorylation of nucleoporins : signal transduction-mediated regulation of their interaction with nuclear transport receptors2010
- Author(s)
  H.Kosako, et al.
- Journal Title
  
  Nucleus
  
  Volume: 1 Pages: 309-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phosphorylation of nucleoporins : signal transduction-mediated regulation of their interaction with nuclear transport receptors.2010
- Author(s)
  Kosako, H., Imamoto, N.
- Journal Title
  
  Nucleus 1
  
  Pages: 309-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phos-tag Western blotting for detecting stoichiometric protein Phosphorylation in cells.2009
- Author(s)
  H.Kosako
- Journal Title
  
  Nature Protocols
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phosphorylation of Nephrin triggers Ca^<2+> signaling by recruitment and activation of phospholipase C-γ1.2009
- Author(s)
  Harita, Y., Kurihara, H., Kosako, H., Tezuka, T., Sekine, T., Igarashi, T., Ohsawa, I., Ohta, S., Hattori, S.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 8951-8962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.2009
- Author(s)
  Kosako, H
- Journal Title
  
  Nature Struct.Mol.Biol. 16
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370041
[Journal Article] (2009)Phos-tag Western blotting for detecting stoichiometric protein phosphorylation in cells.2009
- Author(s)
  Kosako, H.
- Journal Title
  
  Nature Protoc.(Protocol Exchange) 170
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.2009
- Author(s)
  H.Kosako, et al.
- Journal Title
  
  Nature Struct.Mol.Biol. 16
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.2009
- Author(s)
  Kosako, H., Yamaguchi, N., Aranami, C., Ushiyama, M., Kose, S., Imamoto, N., Taniguchi, H., Nishida, E., Hattori, S.
- Journal Title
  
  Nature Struct. Mol. Biol. 16
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19370041
[Journal Article] Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.2009
- Author(s)
  Kosako, H., Yamaguchi, N., Aranami, C., Ushiyama, M., Kose, S., Imamoto, N., Taniguchi, H., Nishida, E., Hattori, S.
- Journal Title
  
  Nature Struct.Mol.Biol. 16
  
  Pages: 1026-1035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Identification of protein kinase substrates by proteomic approaches.2008
- Author(s)
  Hattori, S., Iida, N., Kosako, H.
- Journal Title
  
  Expert Rev.Proteomics 5
  
  Pages: 497-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Nephl, a component of the kidney slit diaphragm, is tyrosine phosphorylated bySrc-family tyrosine kinase and modulates intracellular signaling by binding toGrb2.2008
- Author(s)
  Harita Y, Kurihara H, Kosako H, Tezuka T, Sekine T, Igarashi T, HattoriS.
- Journal Title
  
  J. Biol. Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013013
[Journal Article] Neph1, acomponent of the kidney slit diaphragm,is tyrosine phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.2008
- Author(s)
  Harita, Y., Kurihara, H., Kosako, H., Tezuka, T., Sekine, T., Igarashi, T., Hattori, S.
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 9177-9186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570177
[Journal Article] Purification of phosphoproteins by immobilized metal affinity chromatography and its application to phosphoproteome analysis2007
- Author(s)
  M.Machida, H.Kosako et al.
- Journal Title
  
  FEBS Journal 274(6)
  
  Pages: 1576-1587
- Data Source
  KAKENHI-PROJECT-18770166
[Journal Article] Global analysis of dynamic changes in lipid raft proteins during T-cell activation2007
- Author(s)
  M.Kobayashi, T.Katagiri, H.Kosako et al.
- Journal Title
  
  Electrophoresis 28(in press)
- Data Source
  KAKENHI-PROJECT-18770166
[Journal Article] Extracellular signal-regulated kinase/mitogen-activated protein kinase regulates actin organization and cell motility by phosphorylating the actin cross-linking protein EPLIN2007
- Author(s)
  Han MY, Kosako H, Watanabe T, Hattori S.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 8190-8204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013013
[Journal Article] Global analysis of dynamic changes in lipid raft proteins during T-cell activation.Electrophoresis.2007
- Author(s)
  Kobayashi M, Katagiri T, Kosako H, lida N, Hattori S
- Journal Title
  
  Electrophoresis 28
  
  Pages: 2035-2043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013013
[Journal Article] 2D DIGE技術を用いたリン酸化プロテオーム解析によるシグナル伝達経路構成因子の網羅的同定法2004
- Author(s)
  小迫英尊, 牛山正人, 服部成介
- Journal Title
  
  実験医学 22(9)
  
  Pages: 1299-1304
- Data Source
  KAKENHI-PROJECT-16012211
[Journal Article] 2D DIGE技術を用いたリン酸化プロテオーム解析によるシグナル伝達経路構成因子の網羅的同定法2004
- Author(s)
  小迫英尊, 牛山正人, 服部成介
- Journal Title
  
  実験医学 22(9)
  
  Pages: 1299-1304
- Data Source
  KAKENHI-PROJECT-16770141
[Presentation] 細胞分裂期におけるタンパク質リン酸化の電荷ブロック制御による液-液相分離メカニズムの解明2023
- Author(s)
  山﨑啓也, 高木昌俊, 小迫英尊, 平野達也, 吉村成弘
- Organizer
  第69回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00369
[Presentation] 細胞分裂期におけるタンパク質リン酸化の電荷ブロック制御による液-液相分離メカニズムの解明2023
- Author(s)
  山﨑啓也, 高木昌俊, 小迫英尊, 平野達也, 吉村成弘
- Organizer
  日本放射線影響学会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00369
[Presentation] 先端プロテオーム解析技術を用いた生体内蛋白質間相互作用の大規模解析2022
- Author(s)
  小迫　英尊
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06628
[Presentation] 刺激性微粒子による炎症応答を阻害する生薬由来化合物の解析2021
- Author(s)
  生駒健太，武村直紀，田浦学，小迫英尊，齊藤達哉
- Organizer
  日本薬学会第141年会，一般学術発表（口頭），オンライン開催
- Data Source
  KAKENHI-PROJECT-18KK0229
[Presentation] Global interactome analysis in living cells using advanced proteomic technologies2021
- Author(s)
  Kosako Hidetaka
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06628
[Presentation] 最先端プロテオミクス技術を用いた疾患に関与するシグナル伝達機構の解明2020
- Author(s)
  小迫　英尊
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04966
[Presentation] 刺激性微粒子による炎症応答を抑制する生薬由来化合物の解析2020
- Author(s)
  生駒健太，武村直紀，田浦学，小迫英尊，齊藤達哉
- Organizer
  第70回日本薬学会関西支部大会，ポスター発表，オンライン開催
- Data Source
  KAKENHI-PROJECT-18KK0229
[Presentation] 最先端プロテオミクス技術を用いた疾患に関与するシグナル伝達機構の解明2020
- Author(s)
  小迫　英尊
- Organizer
  第93回日本生化学会大会（招待講演）
- Invited
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] 最先端プロテオミクス技術を用いた疾患に関与するシグナル伝達機構の解明2020
- Author(s)
  小迫　英尊
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06628
[Presentation] Phos-tagと質量分析によるリン酸化シグナル伝達機構の解明2019
- Author(s)
  小迫　英尊
- Organizer
  日本プロテオーム学会2019年大会/第70回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H04966
[Presentation] 線虫遺伝学Xプロテオミクスのコラボ：父性オルガネラオートファジー制御機構の解明を目指して2019
- Author(s)
  佐藤美由紀、佐藤健、小迫英尊
- Organizer
  第19回日本蛋白質科学会年会第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] BioID-based screening of biotinylation sites using Tamavidin 2-REV globally identifies interactors of stimulator of interferon genes (STING)2019
- Author(s)
  Kou Motani and Hidetaka Kosako
- Organizer
  ASCB / EMBO 2019 meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04966
[Presentation] BioID-Based Screening of Biotinylation Sites Globally Identifies STING Interactors2019
- Author(s)
  Kou Motani and Hidetaka Kosako
- Organizer
  Keystone Symposia "Proteomics and its Application to Translational and Precision Medicine"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] BioID-Based Screening of Biotinylation Sites Globally Identifies STING Interactors2019
- Author(s)
  Kou Motani and Hidetaka Kosako
- Organizer
  Keystone Symposia "Proteomics and its Application to Translational and Precision Medicine"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-19H04966
[Presentation] Global identification and functional characterization of protein kinase substrates using various phosphoproteomic technologies2018
- Author(s)
  Hidetaka Kosako
- Organizer
  MSP2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] 疾患に関与する細胞内情報伝達機構を解明するためのリン酸化プロテオミクス技術2018
- Author(s)
  小迫英尊
- Organizer
  日本質量分析学会・日本プロテオーム学会2018年合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] Quantitative interactome and phosphoproteome analysis identifies novel signaling components of Parkinson's disease-associated kinase PINK1.2017
- Author(s)
  H. Kosako, M. Kawano, K. Tanaka and N. Matsuda
- Organizer
  HUPO 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] Phos-tag などのリン酸化プロテオミクス技術による疾患原因キナーゼの機能解析2017
- Author(s)
  小迫英尊
- Organizer
  第68回日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08635
[Presentation] Dissection of protein kinase D signaling during thymocyte development using various phosphoproteomic strategies.2016
- Author(s)
  H. Kosako, E. Ishikawa, S. Yamasaki
- Organizer
  HUPO 2016
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440101
[Presentation] Phos-tagなどのリン酸化プロテオミクス技術の結集によるキナーゼ基質の同定と機能解析2015
- Author(s)
  小迫　英尊
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-02
- Invited
- Data Source
  KAKENHI-PROJECT-26440101
[Presentation] Identification and Functional Analysis of Protein Kinase Substrates using Various Proteomic Technologies,2015
- Author(s)
  小迫　英尊
- Organizer
  Keystone Symposia
- Place of Presentation
  Colorado, USA
- Year and Date
  2015-01-13
- Data Source
  KAKENHI-PROJECT-23570231
[Presentation] 先端プロテオミクス技術によるタンパク質キナーゼ基質の同定と機能解析2015
- Author(s)
  小迫　英尊
- Organizer
  第15回日本蛋白質科学会年会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-26440101
[Presentation] Identification and Functional Analysis of Protein Kinase Substrates using Various Proteomic Technologies,2015
- Author(s)
  小迫英尊
- Organizer
  Keystone Symposia
- Place of Presentation
  Colorado, USA
- Year and Date
  2015-01-13
- Data Source
  KAKENHI-PROJECT-26440101
[Presentation] リン酸化プロテオミクスによるキナーゼ基質の同定と機能解析2014
- Author(s)
  小迫英尊
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-26440101
[Presentation] リン酸化プロテオミクスによるキナーゼ基質の同定と機能解析2014
- Author(s)
  小迫　英尊
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PROJECT-23570231
[Presentation] リン酸化プロテオミクスによるキナーゼ基質の同定と機能解析2014
- Author(s)
  小迫英尊
- Organizer
  日本プロテオーム学会2014年会
- Place of Presentation
  つくば国際会議場(茨城県つくば市）
- Year and Date
  2014-07-17
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113717
[Presentation] MAPキナーゼによるFGヌクレオポリンの多重リン酸化は核─細胞質間輸送を制御する2013
- Author(s)
  小迫英尊
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸コンベンションセンター（兵庫県神戸市）
- Year and Date
  2013-12-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113717
[Presentation] multisite phosphorylation of nucleoporins by ERK and p38 MAP kinases is implicated in the regulation of nuclear transport.2012
- Author(s)
  H. Kosako et al.
- Organizer
  Gordon Research Conference "Phosphorylation G-Protein Mediated Signaling Networks"
- Place of Presentation
  University of New England（米国メイン州）
- Year and Date
  2012-06-11
- Data Source
  KAKENHI-PUBLICLY-24113717
[Presentation] Phosphorylation of FG-repeat nucleoporins by MAP kinases is implicated in the control of nuclear transport.2012
- Author(s)
  H. Kosako et al.
- Organizer
  EMBO Conference "Cellular Signaling Molecular Medicine"
- Place of Presentation
  Hotel Croatia (クロアチア)
- Year and Date
  2012-05-28
- Data Source
  KAKENHI-PUBLICLY-24113717
[Presentation] 蛍光標識二次元ディファレンスゲル電気泳動2D-DIGEから得られた知見と展望.2012
- Author(s)
  小迫英尊
- Organizer
  第63回日本電気泳動学会総会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県）
- Year and Date
  2012-08-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-24113717
[Presentation] Phosphorylation of multiple FG nucleoporins by MAP kinases is involved in the regulation of nucleocytoplasraic transport2011
- Author(s)
  H.Kosako
- Organizer
  Keystone Symposia "Omics Meets Cell Biology"
- Place of Presentation
  Alpbach Congress Centrum(オーストリア国アルプバッハ)
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] プロテオミクスで明らかになったMAPキナーゼによる核膜孔タンパク質群のリン酸化制御2011
- Author(s)
  小迫英尊
- Organizer
  平成23年度日本生化学会関東支部例会
- Place of Presentation
  東京理科大森戸記念館(東京都)(招待講演)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] プロテオミクスで明らかになったMAPキナーゼによるFGヌクレオポリンのリン酸化制御2011
- Author(s)
  小迫英尊
- Organizer
  核ダイナミクス研究会
- Place of Presentation
  北広島クラッセホテル(北海道)
- Year and Date
  2011-10-26
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] Phosphorylation of FG nucleoporins by ERK and p38 MAP kinases is involved in the regulation of nucleocytoplasmic transport2011
- Author(s)
  H.Kosako
- Organizer
  ASCB2011
- Place of Presentation
  Colorado Convention Center(米国コロラド州デンバー)
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] Phosphorylation of FG nucleoporins by MAP kinases is involved in the regulation of nuclear transport2011
- Author(s)
  小迫英尊
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] ERK/MAPキナーゼなどによるFGヌクレオポリンのリン酸化は核輸送因子との相互作用を制御する2010
- Author(s)
  小迫英尊, 他
- Organizer
  BMB2010
- Place of Presentation
  神戸市
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] Phosphoproteomics reveals ERK MAP kinase-mediated regulation of nuclear pore complex proteins.2010
- Author(s)
  Kosako, H.
- Organizer
  BIT's 3^<rd> World Cancer Congress-2010
- Place of Presentation
  シンガポール
- Year and Date
  2010-06-23
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] Phosphoproteomics reveals ERK MAP kinase-mediated regulation of nuclear pore complex proteins.2010
- Author(s)
  H.Kosako
- Organizer
  BIT's 3^<rd> World Cancer Congress-2010
- Place of Presentation
  シンガポール
- Year and Date
  2010-06-23
- Data Source
  KAKENHI-PUBLICLY-22113514
[Presentation] ERK/MAPキナーゼなどによるFGヌクレオポリンのリン酸化は核輸送因子との相互作用を制御する2010
- Author(s)
  小迫英尊, ら
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] Phosphorylation of nuclear pore complex proteins by ERK MAP kinase regulates interaction with transport receptors.2010
- Author(s)
  小迫英尊
- Organizer
  ASCB 49th Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-19370041
[Presentation] リン酸化プロテオミクスによって明らかとなったERK/MAPキナーゼによる核膜孔複合体の機能制御2009
- Author(s)
  小迫英尊, 他
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] リン酸化プロテオミクスによって明らかとなったERK/MAPキナーゼによる核膜孔複合体の機能制御2009
- Author(s)
  小迫英尊, ら
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] Phosphorylation of nuclear pore complex proteins by ERK MAP kinase regulates interaction with transport receptors2009
- Author(s)
  H.Kosako, et al.
- Organizer
  ASCB2009
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] Phosphorylation of nuclear pore complex proteins by ERK MAP kinase regulates interaction with transport receptors.2009
- Author(s)
  Kosako, H., et al.
- Organizer
  ASCB2009
- Place of Presentation
  San Diego, USA
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] Phosphorylation of nuclear pore complex proteins by ERK MAP kinase regulates interaction with transport receotors.2009
- Author(s)
  小迫英尊
- Organizer
  2009 ASCB Annual Meeting
- Place of Presentation
  コンベンションセンター(サンディェゴ)
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-19370041
[Presentation] Phosphoproteomic profiling of ERK MAP kinase signaling reveals a role of phosphorylation in the interaction of nucleoporins with transport factors.2008
- Author(s)
  Kosako, H., et al.
- Organizer
  ASCB2008
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-12-15
- Data Source
  KAKENHI-PROJECT-20570177
[Presentation] 新たなリン酸化プロテオミクスによる細胞内キナーゼ基質の網羅的同定:ERK/MAPキナーゼによるアクチン架橋タンパク質EPLINのリン酸化を介した細胞運動制御2007
- Author(s)
  小迫英尊, ら
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18013013
[Presentation] 新たなリン酸化プロテオミクスによる細胞内キナーゼ基質の網羅的同定:ERK/MAPキナーゼによるアクチン架橋タンパク質EPLINのリン酸イヒを介した細胞運動制御2007
- Author(s)
  小迫英尊他
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-18770166
[Presentation] リン酸化プロテオミクスを用いたキナーゼターゲットの同定と機能解析
- Author(s)
  小迫英尊
- Organizer
  愛媛大学JHUPO第２回サテライトジョイントシンポジウム
- Place of Presentation
  愛媛大学総合情報メディアセンター（愛媛県松山市）
- Invited
- Data Source
  KAKENHI-PROJECT-23570231
[Presentation] 蛍光標識二次元ディファレンスゲル電気泳動2D-DIGEから得られた知見と展望.
- Author(s)
  小迫英尊
- Organizer
  第63回日本電気泳動学会総会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県）
- Invited
- Data Source
  KAKENHI-PROJECT-23570231
[Presentation] Multisite phosphorylation of FG nucleoporins by MAP kinases is involved in the regulation of nucleocytoplasmic transport.
- Author(s)
  H. Kosako et al.
- Organizer
  Cold Spring Harbor Laboratory Meeting "Dynamic Organization of Nuclear Function"
- Place of Presentation
  Cold Spring Harbor Laboratory (米国ニューヨーク州)
- Data Source
  KAKENHI-PROJECT-23570231
[Presentation] リン酸化プロテオミクスを用いたキナーゼターゲットの同定と機能解析
- Author(s)
  小迫英尊
- Organizer
  第2回JHUPOサテライトジョイントシンポジウム
- Place of Presentation
  愛媛大学総合情報メディアセンター（愛媛県）
- Invited
- Data Source
  KAKENHI-PROJECT-23570231

1. TANIGUCHI Hisaaki (10257636)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. NAKAYA Michio (80464387)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. KONISHI Hiroaki (40252811)

# of Collaborated Projects: 2 results

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4. FUJIWARA Kazuko (20108880)

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5. IKEDA Kazuko (10108863)

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6. Noguchi Rei (30779682)

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# of Collaborated Products: 1 results
7. 小林道元 (00345034)

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8. 服部成介 (50143508)

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9. 近藤格 (30284061)

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10. MAITA Nobuo (00404046)

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16. KOZUKA Yuji (50378311)

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17. SHIMOJO Naoshi (70410751)

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18. Oh-hora Masatsugu (40351506)

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21. NAKAFUKU Masato (80202216)

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22. saitoh tatsuya (60456936)

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23. Nakaoka Yoshikazu (90393214)

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24. 飯田直幸 (10376618)

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26. 岡崎拓 (00362468)

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27. 亀山昭彦 (80415661)

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28. 吉松有紀 (60808632)

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29. 川井章 (90252965)

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33. 澤崎達也 (50314969)

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34. 土方敦司 (80415273)

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35. 増本純也 (20334914)

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36. 吉浦孝一郎 (00304931)

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37. 竹田浩之 (40609393)

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38. 岸田大 (50467180)

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39. 山中聡士 (50853884)

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40. 右田清志 (60264214)

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43. 古賀智裕 (90537284)

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44. OHMURAYA Masaki

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45. TERABAYASHI Takeshi

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46. MOTANI Kou

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47. KOSHIBA Takumi

# of Collaborated Projects: 0 results

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48. IMAI Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. OYADOMARI Seiichi

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50. 田中啓二

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51. 松尾芳隆

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# of Collaborated Products: 1 results
52. 佐々木妙子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 岡敏彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
54. 尾勝圭

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
55. 山崎啓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
56. 圓岡真宏

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# of Collaborated Products: 1 results
57. 親泊美帆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
58. 中村修平

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# of Collaborated Products: 1 results

Kosako Hidetaka 小迫 英尊

KOSAKO Hidetaka 小迫 英尊

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先端プロテオミクス技術の開発による自然免疫シグナルの新規制御機構の解明Principal Investigator

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Global proteomic analysis of the PINK1-Parkin pathway and elucidation of mitochondrial regulationPrincipal Investigator

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自然免疫分子STINGを介したシグナル伝達経路の重層的プロテオーム解析Principal Investigator

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Advanced proteomic analysis of signaling pathays mediated by Parkinson's disease-associated kinase PINK1Principal Investigator

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Kosako Hidetaka 小迫英尊

KOSAKO Hidetaka 小迫英尊