TAJIMA Orie 田島織絵

Researcher Number	10362237
External Links
Affiliation (Current)	2025: 中部大学, 生命健康科学部, 准教授
Affiliation (based on the past Project Information) *help	2012 – 2014: 中部大学, 生命健康科学部, 准教授 2009: Chubu University, 生命健康科学部, 准教授 2006 – 2008: Chubu University, College of life and health sciences, Assistant Professor, 生命健康科学部, 講師 2005: 名古屋大学, 大学院医学系研究科, 助手 2004 – 2005: 名古屋大学, 大学院・医学系研究科, 助手
Review Section/Research Field	Principal Investigator General medical chemistry / Neurochemistry/Neuropharmacology / Nerve anatomy/Neuropathology / Dermatology Except Principal Investigator General medical chemistry
Keywords	Principal Investigator ガングリオシド / スフィンゴ糖脂質 / 神経変性 / ノックアウト / 中枢神経 / 遺伝子発現 / 末梢神経 / 腸管上皮細胞 / 脂肪酸輸送体 / 脂質ラフト … More / 脂肪酸吸収 / Ninjurin2 / 神経再生分子 / ラフト / 神経機能障害 / 知覚神経 / 皮膚損傷 … More Except Principal Investigator inflammation / raft / ganglioside / degeneration / neuron / nerve / glycolipid / knockout / セロトニン / アセチルコリン / 遺伝子発現 / GD3 / 補体 / グリア / 神経変性 / スフィンゴ糖脂質 / 炎症 / ラフト / ガングリオシド / 変性 / ニューロン / 神経 / 糖脂質 / ノックアウト Less

Roles of glycosphingolipids in enterocytes for lipid absorptionPrincipal Investigator
- Principal Investigator
  
  TAJIMA Orie
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Chubu University
Mechanisms of lipid raft disturbance and role of raft-related neurogenerational molecules in the GM3 only micePrincipal Investigator
- Principal Investigator
  
  TAJIMA Orie
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Chubu University
糖鎖変異マウスに見られた神経変性の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  田島織絵
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Chubu University
糖鎖変異マウスに見られた難治性皮膚損傷の分子メカニズムPrincipal Investigator
- Principal Investigator
  
  田島織絵
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Nagoya University
Mechanisms for the biosignal regulation with glycosphingolipids and their redundancy
- Principal Investigator
  
  FURUKAWA Kouichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Nagoya University

All 2014 2013 2012 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Ganglioside deficiellcy causes inflammation and neurodegeneration via the activation of complement system in the spinal cord.2014
- Author(s)
  Yuhsuke Ohmi, Yuki Ohkawa, et al.
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 61(印刷中) Issue: 1 Pages: 61-61
- DOI
  10.1186/1742-2094-11-61
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J08954, KAKENHI-PROJECT-23590371, KAKENHI-PUBLICLY-24111519, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24790298, KAKENHI-PROJECT-25670141, KAKENHI-PROJECT-26860321
[Journal Article] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6.2014
- Author(s)
  Miyata M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 445 Issue: 2 Pages: 504-10
- DOI
  10.1016/j.bbrc.2014.02.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-24390078, KAKENHI-PROJECT-24590768, KAKENHI-PROJECT-24790298, KAKENHI-PROJECT-24791182, KAKENHI-PROJECT-26870682
[Journal Article] Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues.2012
- Author(s)
  Ohmi Y, Ohkawa Y, Yamauchi Y, Tajima O, Furukawa K, Furukawa K
- Journal Title
  
  Neurochem Res
  
  Volume: 36(9) Pages: 578-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790298
[Journal Article] Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice2010
- Author(s)
  Tajima O
- Journal Title
  
  Behav.Brain Res 206
  
  Pages: 101-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice.2010
- Author(s)
  Tajima O, Egashira N, Ohmi Y, Fukue Y, Mishima K, Iwasaki K, Fujiwara M, Sugiura Y, Furukawa K, Furukawa K.
- Journal Title
  
  Behav Brain Res 206
  
  Pages: 101-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues.2009
- Author(s)
  Ohmi Y, Tajima O, Ohkawa Y, Mori A, Sugiura Y, Furukawa K, Furukawa K.
- Journal Title
  
  Proc Natl Acad Sci U S A 106
  
  Pages: 722405-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: Sensitivity analysis with glycosylation-defective mutant mice.2009
- Author(s)
  Kondo Y, Tokuda N, Fan X, Yamashita T, Honke K, Takematsu H, Togayachi A, Ohta M, Kotzusumi Y, Narimatsu H, Tajima O, Furukaw K, Furukawa K.
- Journal Title
  
  Biochem Biophys Res Commun 378
  
  Pages: 179-81
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] 神経の分化と糖脂質.2009
- Author(s)
  古川鋼一、大海雄介、徳田典代、古川圭子、田島織絵
- Journal Title
  
  生体の科学 60
  
  Pages: 187-193
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] Reduced motor and sensory functions and emotional response in GM3-only mice: emergence from early stage of life and exacerbation with aging.2009
- Author(s)
  Tajima O, Egashira N, Ohmi Y, Fukue Y, Mishima K, Iwasaki K, Fujiwara M, Inokuchi J, Sugiura Y, Furukawa K, Furukawa K.
- Journal Title
  
  Behav Brain Res 198
  
  Pages: 74-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] Impaired hypoglossal nerve regeneration in the mutant mice lacking complex gangliosides: down-regulation of neurotrophic factors and receptors as possible mechanisms.2008
- Author(s)
  Kittaka D, Itoh MI, Ohmi Y, Kondo Y, Fukumoto S, Urano T, Tajima O, Furukawa K, Furukawa K.
- Journal Title
  
  Glycobiology 18
  
  Pages: 509-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20700342
[Journal Article] Knockout mice and glycolipids.2007
- Author(s)
  Furukawa K, Tajima O, Okuda T, Tokuda N, Furukawa K.
- Journal Title
  
  In Comprehensive glycoscience. (Elsevier, Oxford, UK) Article No: 00086 (in press)
- Data Source
  KAKENHI-PROJECT-18700350
[Journal Article] Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.2006
- Author(s)
  Okuda T, Tokuda N, Numata SI, Ito M, Ohta M, Kawamura K, Wiels J, Urano T, Tajima O, Furukawa K, Furukawa K
- Journal Title
  
  J.Biol.Chem. (in press)
- Data Source
  KAKENHI-PROJECT-16790636
[Journal Article] Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins.2006
- Author(s)
  Okuda T, Tokuda N, Numata S, Ito M, Ohta M, Kawamura K, Wiels J, Urano T, Tajima O, Furukawa K, Furukawa K.
- Journal Title
  
  J.Biol.Chem. 281・15
  
  Pages: 10230-10235
- Data Source
  KAKENHI-PROJECT-18700350
[Journal Article] Sensory nerve-dominant nerve degeneration and remodeling in the mutant mice lacking complex gangliosides.2005
- Author(s)
  Sugiura Y, Furukawa K, Tajima O, Mii S, Honda T, Furukawa K.
- Journal Title
  
  Neuroscience 135・4
  
  Pages: 1167-1186
- Data Source
  KAKENHI-PROJECT-16790636
[Journal Article] ガングリオシド合成酵素ノックアウトマウスにおける神経機能解析2004
- Author(s)
  古川鋼一, 杉浦康夫, 田島織絵, 本多たかし, 古川圭子
- Journal Title
  
  蛋白質核酸酵素 49・15
  
  Pages: 2411-2416
- Data Source
  KAKENHI-PROJECT-16790636
[Presentation] アストロサイトにおけるガングリオシド糖鎖の機能2013
- Author(s)
  大海雄介、大川祐樹、姫シュウテイ、大平拡、田島織絵、古川圭子、古川鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] TNFα及び紫外線によるメラノサイトとメラノーマのGD3合成酵素遺伝子の発現誘導2013
- Author(s)
  古川圭子、宮田麻衣子、田島織絵、神戸真理子、祖父江沙矢加、市原正智、杉浦一充、古川鋼一
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] 糖鎖変異による脂質吸収障害の分子メカニズム2013
- Author(s)
  田島織絵、藤田雄輝、桐谷美咲、雨宮慶、宮田麻衣子、徳田典代、田口良、古川鋼一、古川圭子
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] 糖鎖変異による小腸機能障害の分子メカニズム2012
- Author(s)
  田島織絵、藤田雄輝、宮田麻衣子、徳田典代、田口良、大海雄介、大川祐樹、古川圭子、古川鋼一
- Organizer
  第32回日本糖質学会大会
- Place of Presentation
  鹿児島、日本
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] 腸管上皮細胞におけるスフィンゴ糖脂質の役割2012
- Author(s)
  田島織絵、藤田雄輝、宮田麻衣子、徳田典代、田口良、大海雄介、大川祐樹、古川鋼一、古川圭子
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡、日本
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] GM3-onlyマウスの中枢神経系で高発現するPerilipin4はミクログリアに発現しリソソーム機能を亢進させる2012
- Author(s)
  大川祐樹、大海雄介、田島織絵、百田洋之、加藤彰、夏目敦至、若林俊彦、古川圭子、古川鋼一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡、日本
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] 糖鎖欠損マウスにおける進行性神経機能障害の基盤としてのアセチルコリン受容体異常.2009
- Author(s)
  田島織絵
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-20700342
[Presentation] 糖鎖欠損マウスにおける進行性神経機能障害の基盤としてのアセチルコリン受容体異常2009
- Author(s)
  田島織絵
- Organizer
  第82回日本生化学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-20700342
[Presentation] 糖鎖欠損マウスにおける神経再生関連分子の探索 : Ninjurin2の神経機能制御メカニズム2008
- Author(s)
  田島織絵
- Organizer
  第81回日本生化学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-20700342
[Presentation] 糖鎖欠損マウスにおける神経再生関連分子の探索:Ninjurin2の神経機能制御メカニズム.2008
- Author(s)
  田島織絵
- Organizer
  第81回日本生化学会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PROJECT-20700342
[Presentation] Identification of neuronal degeneration- and regeneration-related molecules using GM3 only mice.2007
- Author(s)
  Tajima O
- Organizer
  XIX International Symposium on Glycoconjugates
- Place of Presentation
  ケアンズ,オーストラリア
- Year and Date
  2007-07-19
- Data Source
  KAKENHI-PROJECT-18700350
[Presentation] Identification of neuronal degeneration-and regeneration-related molecules using GM3 only mice: roles of an adhesion molecule Ninjurin2 in nervous systems.2007
- Author(s)
  Tajima O
- Organizer
  第80回日本生化学会
- Place of Presentation
  横浜,日本
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18700350
[Presentation] 糖鎖変異に伴う脂質代謝障害の検討
- Author(s)
  田島織絵、桐谷美咲、古川鋼一、古川圭子
- Organizer
  第33回日本糖質学会大会
- Place of Presentation
  愛知県・名古屋
- Year and Date
  2014-08-10 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-24790298
[Presentation] 糖脂質糖鎖改変マウスにおける脂質代謝障害の分子メカニズム
- Author(s)
  田島織絵、桐谷美咲、古川鋼一、古川圭子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都府・京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24790298

1. FURUKAWA Kouichi (80211530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. URANO Takeshi (70293701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. FURUKAWA Keiko (50260732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAJIMA Orie 田島 織絵

Research Projects

Research Products

Co-Researchers

Roles of glycosphingolipids in enterocytes for lipid absorptionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of lipid raft disturbance and role of raft-related neurogenerational molecules in the GM3 only micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糖鎖変異マウスに見られた神経変性の分子メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

糖鎖変異マウスに見られた難治性皮膚損傷の分子メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms for the biosignal regulation with glycosphingolipids and their redundancy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ganglioside deficiellcy causes inflammation and neurodegeneration via the activation of complement system in the spinal cord.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] UVB-irradiated keratinocytes induce melanoma-associated ganglioside GD3 synthase gene in melanocytes via secretion of tumor necrosis factor α and interleukin 6.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Essential roles of gangliosides in the formation and maintenance of membrane microdomains in brain tissues.2012

Author(s)

Journal Title

Data Source

[Journal Article] Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice2010

Author(s)

Journal Title

Data Source

[Journal Article] Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice.2010

Author(s)

Journal Title

Data Source

[Journal Article] Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues.2009

Author(s)

Journal Title

Data Source

[Journal Article] Glycosphingolipids are not pivotal receptors for Subtilase cytotoxin in vivo: Sensitivity analysis with glycosylation-defective mutant mice.2009

Author(s)

Journal Title

Data Source

[Journal Article] 神経の分化と糖脂質.2009

Author(s)

Journal Title

Data Source

[Journal Article] Reduced motor and sensory functions and emotional response in GM3-only mice: emergence from early stage of life and exacerbation with aging.2009

Author(s)

Journal Title

Data Source

[Journal Article] Impaired hypoglossal nerve regeneration in the mutant mice lacking complex gangliosides: down-regulation of neurotrophic factors and receptors as possible mechanisms.2008

Author(s)

Journal Title

Data Source

[Journal Article] Knockout mice and glycolipids.2007

Author(s)

Journal Title

Data Source

TAJIMA Orie 田島織絵