Morita Masanobu 守田匡伸

… Alternative Names

MORITA Masanobu 守田匡伸

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Researcher Number	10519094
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2019 – 2024: 東北大学, 医学系研究科, 講師 2017 – 2018: 東北大学, 医学系研究科, 助教 2015: 東北大学, 医学系研究科, 助教 2014: 東北大学, 大学院医学系研究科・医化学分野, 助教 2012 – 2014: 東北大学, 医学(系)研究科(研究院), 助教 2010 – 2011: 東北大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 48040:Medical biochemistry-related / Regenerative medicine / Tumor biology Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 49070:Immunology-related / Basic Section 48040:Medical biochemistry-related / Basic Section 56020:Orthopedics-related / Risk sciences of radiation and chemicals / General medical chemistry / Experimental pathology
Keywords	Principal Investigator 超硫黄分子 / ミトコンドリア / ゲノム編集 / エネルギー代謝 / イオウ呼吸 / 硫黄呼吸 / 硫黄代謝 / 再生医療 / iPS / リプログラミング / 幹細胞 / がん微小環境 … More Except Principal Investigator … More 超硫黄分子 / 超硫黄 / 炎症 / 環境性肺疾患 / マクロファージ / 環境微粒子 / 肺炎 / 免疫応答 / 炎症性腸疾患 / T細胞 / パースルフィド合成酵素 / アミノアシルtRNA合成酵素 / システインパースルフィド / 受容体 / 炭素微粒子 / Tim4 / マイクロプラスチック / 環境炭素微粒子 / 炎症毒性 / 免疫受容体 / カーボンナノチューブ / 貪食 / スカベンジャー受容体ファミリー / 粒子状化学物質 / マウス / 肺疾患 / 炎症応答 / 肺胞マクロファージ / 粉塵 / シリカ / スカベンジャー受容体 / 異所性脂肪浸潤 / 筋内異所性骨化 / 異所性骨化 / 筋内脂肪浸潤 / 細胞･組織 / 環境 / Mrf2 / 細胞・組織 / 環境応答 / 活性酸素 / Nrf2 / 遺伝子組換えマウス / DNA損傷 / 突然変異 / アポトーシス / MIS応答 / 皮膚 / 紫外線 / コンディショナルノックダウン / DNAメチル化 / ヒストンメチル化 / SAM合成酵素 / エピジェネティクス / 肺上皮細胞分化 / Nrf2－Keap1 / Nrf2-Keap1 / 肺再生 Less

超硫黄分子の代謝制御メカニズムの解明Principal Investigator
- Principal Investigator
  
  守田匡伸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tohoku University
Discovery of a novel persulfide synthase and analysis of its physiological function.
- Principal Investigator
  
  井田智章
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Osaka Metropolitan University
Regulation of T cell immune responses by supersulfide
- Principal Investigator
  
  石井直人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tohoku University
Pathological role of Carbon Particle Receptors in environmental lung diseases
- Principal Investigator
  
  中山勝文
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Ritsumeikan University
Functional analysis of sulfur metabolism and respiratory system: genome editing and energy metabolism analysisPrincipal Investigator
- Principal Investigator
  
  Morita Masanobu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Tohoku University
Pathological role of scavenger receptor family molecules in lung diseases associated with environmental particles
- Principal Investigator
  
  Masafumi Nakayama
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Ritsumeikan University
Mechanism analysis of fatty infiltration and ectopic ossification in muscles
- Principal Investigator
  
  Taniguchi Noboru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kagoshima University
Mecahistic analysis of a protective response of skin tissue to UV genotoxicity
- Principal Investigator
  
  IKEHATA Hironobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tohoku University
Lung regeneration from iPS by using Nrf2 activator
- Principal Investigator
  
  SATOH Hironori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  National Cancer Center Japan
  Tohoku University
Methods rewriting epigenome as the target of methyonine adenosyltransferase II
- Principal Investigator
  
  KATOH Yasutake
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
differentiation and reprogramming regulated by oxidative stressPrincipal Investigator
- Principal Investigator
  
  MORITA Masanobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Tohoku University
Oxidative stress signal function in stem cells via keap1-Nrf2 systemPrincipal Investigator
- Principal Investigator
  
  MORITA Masanobu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2016 2011

All Journal Article Presentation Book

[Book] 光と生命の事典2016
- Author(s)
  池畑広伸，真嶋哲朗、飯野盛利、七田芳則、藤堂剛、秋山（張）秋梅、伊吹裕子、森俊雄、日出間純、錦織千佳子、守田明理、竹内聖二、大平明弘、上出良一、田中淳、船坂陽子、渡辺正勝、森脇真一、菅澤薰、寺西美佳，松永司、安倍学、蟻川謙太郎、安東宏徳、飯郷雅之、池内昌彦、池田憲昭、池田啓、井澤毅、石川大太郎、石川満　他（共著）
- Total Pages
  422
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-15H02815
[Book] Survival strategy and disease pathogenesis according to the Nrf2-small Maf heterodimer2011
- Author(s)
  Masanobu Morita, Hozumi Motohashi
- Publisher
  Wiley-Blackwell
- Data Source
  KAKENHI-PROJECT-22700870
[Journal Article] Supersulfides support bone growth by promoting chondrocyte proliferation in the growth plates2024
- Author(s)
  Sasama Yuji、Yoshimura Kentaro、Hoshino Marie、Sasa Kiyohito、Akaike Takaaki、Morita Masanobu、Baba Kazuyoshi、Shirota Tatsuo、Miyamoto Yoichi
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 66 Issue: 1 Pages: 76-81
- DOI
  10.1016/j.job.2023.11.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-21K09835, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K10877, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277
[Journal Article] Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality2024
- Author(s)
  Nishimura Akira、Yoon Sunghyeon、Matsunaga Tetsuro、Ida Tomoaki、Jung Minkyung、Ogata Seiryo、Morita Masanobu、Yoshitake Jun、Unno Yuka、Barayeu Uladzimir、Takata Tsuyoshi、Takagi Hiroshi、Motohashi Hozumi、van der Vliet Albert、Akaike Takaaki
- Journal Title
  
  Redox Biology
  
  Volume: 69 Pages: 103018-103018
- DOI
  10.1016/j.redox.2023.103018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-22K11796, KAKENHI-PROJECT-23K06094, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K06386, KAKENHI-PROJECT-21K05504, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PROJECT-21H04799
[Journal Article] 2H-Thiopyran-2-thione sulfine, a compound for converting H2S to HSOH/H2S2 and increasing intracellular sulfane sulfur levels2024
- Author(s)
  Cui Qi、Shieh Meg、Pan Tony W.、Nishimura Akiyuki、Matsunaga Tetsuro、Kelly Shane S.、Xu Shi、Jung Minkyung、Ogata Seiryo、Morita Masanobu、Yoshitake Jun、Chen Xiaoyan、Robinson Jerome R.、Qian Wei-Jun、Nishida Motohiro、Akaike Takaaki、Xian Ming
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2453-2453
- DOI
  10.1038/s41467-024-46652-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-23K24035
[Journal Article] Supersulfide catalysis for nitric oxide and aldehyde metabolism2023
- Author(s)
  Kasamatsu Shingo、Nishimura Akira、Alam Md. Morshedul、Morita Masanobu、Shimoda Kakeru、Matsunaga Tetsuro、Jung Minkyung、Ogata Seiryo、Barayeu Uladzimir、Ida Tomoaki、Nishida Motohiro、Nishimura Akiyuki、Motohashi Hozumi、Akaike Takaaki
- Journal Title
  
  Science Advances
  
  Volume: 9 Issue: 33 Pages: 1-11
- DOI
  10.1126/sciadv.adg8631
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06148, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K06386, KAKENHI-PROJECT-21K05504, KAKENHI-PROJECT-22K19395, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-23K24035
[Journal Article] Supersulphides provide airway protection in viral and chronic lung diseases2023
- Author(s)
  Matsunaga Tetsuro、Sano Hirohito、Takita Katsuya、Morita Masanobu、Yamanaka Shun、Ichikawa Tomohiro、Numakura Tadahisa、Ida Tomoaki、Jung Minkyung、Ogata Seiryo、Yoon Sunghyeon、Fujino Naoya、Kyogoku Yorihiko、Akaike Takaaki、et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 4476-4476
- DOI
  10.1038/s41467-023-40182-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K06386, KAKENHI-PROJECT-21K08148, KAKENHI-PROJECT-21K16104, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PLANNED-21H05253, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PLANNED-21H05267, KAKENHI-PROJECT-21H04758, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-23K21370, KAKENHI-PROJECT-23K27640
[Journal Article] Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?2023
- Author(s)
  Griffiths Kayleigh、Ida Tomoaki、Morita Masanobu、Lamb Reece J.、Lee Jordan J.、Frenneaux Michael P.、Fukuto Jon M.、Akaike Takaaki、Feelisch Martin、Madhani Melanie
- Journal Title
  
  Redox Biology
  
  Volume: 60 Pages: 102605-102605
- DOI
  10.1016/j.redox.2023.102605
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K06386, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277
[Journal Article] Synthesis of sulfides and persulfides is not impeded by disruption of three canonical enzymes in sulfur metabolism2023
- Author(s)
  Zainol Abidin Qamarul Hafiz、Ida Tomoaki、Morita Masanobu、Matsunaga Tetsuro、Nishimura Akira、Jung Minkyung、Hassan Naim、Takata Tsuyoshi、Ishii Isao、Kruger Warren、Wang Rui、Motohashi Hozumi、Tsutsui Masato、Akaike Takaaki
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 4 Pages: 868-868
- DOI
  10.3390/antiox12040868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07554, KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-20K15983, KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-22K08261, KAKENHI-PROJECT-23K06094, KAKENHI-PROJECT-23K06145, KAKENHI-PROJECT-23K06386, KAKENHI-PROJECT-21K05504, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05264, KAKENHI-PUBLICLY-22H05577, KAKENHI-PROJECT-21H04799
[Journal Article] Persulfide biosynthesis conserved evolutionarily in all organisms2023
- Author(s)
  Ogata Seiryo、Matsunaga Tetsuro、Jung Minkyung、Barayeu Uladzimir、Morita Masanobu、Akaike Takaaki
- Journal Title
  
  Antioxidants Redox Signaling
  
  Volume: 39 Issue: 13-15 Pages: 983-999
- DOI
  10.1089/ars.2023.0405
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K14333, KAKENHI-PROJECT-23K14341, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K06893, KAKENHI-PROJECT-23K06145, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277
[Journal Article] Heterozygous variants in GATA2 contribute to DCML deficiency in mice by disrupting tandem protein binding.2022
- Author(s)
  Hasegawa A, Hayasaka Y, Morita M, Takenaka Y, Hosaka Y, Hirano I, Yamamoto M, Shimizu R.
- Journal Title
  
  Commun Biol.
  
  Volume: - Issue: 1 Pages: 376-376
- DOI
  10.1038/s42003-022-03316-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03555, KAKENHI-PROJECT-21K08364, KAKENHI-PROJECT-19K07341
[Journal Article] 8-Nitro-cGMP suppresses mineralization by mouse osteoblasts2022
- Author(s)
  Kaneko K, Miyamoto Y, Ida T, Morita M, Yoshimura K, Nagasaki K, Toba K, Sugisaki R, Motohashi H, Akaike T, Chikazu D, Kamijo R
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 71 Issue: 3 Pages: 191-197
- DOI
  10.3164/jcbn.21-129
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09835, KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-22K19635, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-22H03256
[Journal Article] Glenoid bone resorption after Bankart repair: finite element analysis of postoperative stress distribution of the glenoid2021
- Author(s)
  Inoue K, Suenaga N, Oizumi N, Yamaguchi H, Miyoshi N, Taniguchi N, Morita S, Munemoto M, Kurata S, Tanaka Y.
- Journal Title
  
  J Shoulder Elbow Surg
  
  Volume: 30 Issue: 1 Pages: 188-193
- DOI
  10.1016/j.jse.2020.04.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09036
[Journal Article] Methods in sulfide and persulfide research.2021
- Author(s)
  Takata Tsuyoshi, Jung Minkyung, Matsunaga Tetsuro, Ida Tomoaki, Morita Masanobu, Motohashi Hozumi, Shen Xinggui, Kevil Christopher G., Fukuto Jon M., Akaike Takaaki.
- Journal Title
  
  Nitric Oxide
  
  Volume: 116 Pages: 47-64
- DOI
  10.1016/j.niox.2021.09.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21496, KAKENHI-PUBLICLY-20H04832, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05263, KAKENHI-PLANNED-21H05264, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-19K07554, KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-20K15983, KAKENHI-PROJECT-17H06170
[Journal Article] Virucidal effect of monogalactosyl diacylglyceride from a green microalga, Coccomyxa sp. KJ, against clinical isolates of SARS-CoV-2 as assessed by a plaque assay.2021
- Author(s)
  Hayashi Kyoko, Asai Satomi, Umezawa Kazuo, Kakizoe Hidehumi, Miyachi Hayato, Morita Masanobu, Akaike Takaaki, Kuno Hitoshi, Komatsu Satoko, Watanabe Takumi, Kawahara Toshio.
- Journal Title
  
  Journal of Clinical Laboratory Analysis
  
  Volume: 36 Issue: 1
- DOI
  10.1002/jcla.24146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21496, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-17H06170
[Journal Article] Sulfide catabolism ameliorates hypoxic brain injury.2021
- Author(s)
  Marutani E, Morita M, Hirai S, Kai S, Grange RMH, Miyazaki Y, Nagashima F, Traeger L, Magliocca A, Ida T, Matsunaga T, Batten A, Li R, Tanaka T, Ikeda T, Nakagawa A, Atochin DN, Ihara H, Olenchock BA, Shen X, Nishida M, Hanaoka K, Kevil CG, Xian M, Bloch DB, Akaike T, Hindle AG, Motohashi H, Ichinose F, et al.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 3108-3108
- DOI
  10.1038/s41467-021-23363-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21496, KAKENHI-PUBLICLY-20H04767, KAKENHI-PUBLICLY-20H04832, KAKENHI-PUBLICLY-20H05512, KAKENHI-PLANNED-21H05263, KAKENHI-PLANNED-21H05269, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-21H04799, KAKENHI-PROJECT-19H03383, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-19K07554, KAKENHI-PROJECT-20K07306, KAKENHI-PROJECT-17H06170
[Journal Article] Heparan sulfate promotes differentiation of white adipocytes to maintain insulin sensitivity and glucose homeostasis2021
- Author(s)
  Matsuzawa Takuro、Morita Masanobu、Shimane Ai、Otsuka Rina、Mei Yu、Irie Fumitoshi、Yamaguchi Yu、Yanai Kazuhiko、Yoshikawa Takeo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 297 Issue: 3 Pages: 101006-101006
- DOI
  10.1016/j.jbc.2021.101006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20J11179, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-21K06795
[Journal Article] Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation2021
- Author(s)
  Omori S, Tsugita M, Hoshikawa Y, Morita M, Ito F, Yamaguchi SI, Xie Q, Noyori O, Yamaguchi T, Takada A, Saitoh T, Toyokuni S, Akiba H, Nagata S, Kinoshita K, Nakayama M
- Journal Title
  
  Cell reports
  
  Volume: 34 Issue: 6 Pages: 108734-108734
- DOI
  10.1016/j.celrep.2021.108734
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-15H05785, KAKENHI-PLANNED-17H06415, KAKENHI-PROJECT-19H03371, KAKENHI-PROJECT-19H03880, KAKENHI-PROJECT-19K22808, KAKENHI-PROJECT-18KK0229, KAKENHI-PROJECT-20H03472, KAKENHI-ORGANIZER-17H06413
[Journal Article] Humeral bone resorption after reverse shoulder arthroplasty using uncemented stem.2020
- Author(s)
  Inoue K, Suenaga N, Oizumi N, Yamaguchi H, Miyoshi N, Taniguchi N, Morita S, Munemoto M, Kurata S, Tanaka Y.
- Journal Title
  
  JSES Int
  
  Volume: 4 Issue: 1 Pages: 138-143
- DOI
  10.1016/j.jses.2019.11.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09036
[Journal Article] Production of IL-17A at innate immune phase leads to decreased Th1 immune response and attenuated host defense against infection with Cryptococcus deneoformans2020
- Author(s)
  Sato K, Yamamoto H, Nomura T, Kasamatsu J, Miyasaka T, Tanno D, Matsumoto I, Kagesawa T, Miyahara A, Zong T, Oniyama A, Kawamura K, Yokoyama R, Kitai Y, Ishizuka S, Kanno E, Tanno H, Suda H, Morita M, Yamamoto M, Iwakura Y, Ishii K, Kawakami K
- Journal Title
  
  The Journal of Immunology
  
  Volume: 205 Issue: 3 Pages: 686-698
- DOI
  10.4049/jimmunol.1901238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07341, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02851, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K17920
[Journal Article] The establishment of a novel high-throughput screening system using RNA-guided genome editing to identify chemicals that suppress aldosterone synthase expression2020
- Author(s)
  Ito R, Morita M, Nakano T, Sato I, Yokoyama A, Sugawara A
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 534 Pages: 672-679
- DOI
  10.1016/j.bbrc.2020.11.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-20H04099, KAKENHI-PROJECT-19K22793, KAKENHI-PROJECT-19K17952
[Journal Article] Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap12019
- Author(s)
  Suzuki Takafumi、Muramatsu Aki、Saito Ryota、Iso Tatsuro、Shibata Takahiro、Kuwata Keiko、Kawaguchi Shin-ichi、Iwawaki Takao、Adachi Saki、Suda Hiromi、Morita Masanobu、Uchida Koji、Baird Liam、Yamamoto Masayuki
- Journal Title
  
  Cell Reports
  
  Volume: 28 Issue: 3 Pages: 746-758
- DOI
  10.1016/j.celrep.2019.06.047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H00990, KAKENHI-PROJECT-19H01019, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17H06170, KAKENHI-ORGANIZER-15H05935
[Journal Article] Mitochondrial cysteinyl-tRNA synthetase is expressed via alternative transcriptional initiation regulated by energy metabolism in yeast cells2019
- Author(s)
  Nishimura Akira、Nasuno Ryo、Yoshikawa Yuki、Jung Minkyung、Ida Tomoaki、Matsunaga Tetsuro、Morita Masanobu、Takagi Hiroshi、Motohashi Hozumi、Akaike Takaaki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 294 Issue: 37 Pages: 13781-13788
- DOI
  10.1074/jbc.ra119.009203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-19K07554, KAKENHI-PROJECT-19K15803, KAKENHI-PROJECT-19K16129, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-18K07099, KAKENHI-PROJECT-19H05639
[Journal Article] Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.2018
- Author(s)
  Yoshida E, Suzuki T, Morita M, Taguchi K, Tsuchida K, Motohashi H, Doita M, and Yamamoto M
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 5 Pages: 386-392
- DOI
  10.1111/gtc.12579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15590, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508
[Journal Article] Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response2016
- Author(s)
  Saito R, Suzuki T, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L, Furusawa Y, Negishi T, Ichinose M, Yamamoto M.
- Journal Title
  
  Molecular and Cellular Biology.
  
  Volume: 36 Issue: 2 Pages: 271-284
- DOI
  10.1128/mcb.00868-15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815
[Presentation] 超硫黄触媒酵素: アルコールデヒドロゲナーゼ 5（ADH5）による NO シグナル機能の制御メカニズム2024
- Author(s)
  守田匡伸
- Organizer
  第22回分子予防環境医学研究会大会
- Data Source
  KAKENHI-PROJECT-23K06145
[Presentation] Discovery of new persulfide synthases that are expressed among all organisms during their evolution2023
- Author(s)
  Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Tetsuro Matsunaga, Yuka Unno, Ayumu Kobayashi, Yasuhiro Ishimaru, Nobuyuki Uozumi, Hozumi Motohashi, Shingo Kasamatsu, Hideshi Ihara, Takaaki Akaike
- Organizer
  新興硫黄生物学が拓く生命原理変革（硫黄生物学）第３回領域会議
- Data Source
  KAKENHI-PROJECT-23K06386
[Presentation] 超硫黄触媒によるホルムアルデヒド代謝とNOシグナル制御2023
- Author(s)
  守田匡伸, 松永哲郎, 笠松真吾, Alam Md. Morshedul, Jung Minkyung, 緒方星陵, Barayeu Uladzimir , 井田智章, 西田基宏, 本橋ほづみ, 赤池孝章
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K06145
[Presentation] 超硫黄触媒酵素としてのアルコールデヒドロゲナーゼ5(ADH5)のNOシグナル制御メカニズム2023
- Author(s)
  守田匡伸、松永哲郎、笠松真吾、西村明、Md. Morshedul Alam、下田翔、井田智章、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第76回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06145
[Presentation] 超硫黄触媒酵素: アルコールデヒドロゲナーゼ5（ADH5）による NOシグナル機能の制御メカニズム2022
- Author(s)
  守田匡伸、松永哲郎、笠松真吾、西村明、Md. Morshedul Alam、下田翔、西村明幸、緒方星陵、Jung Minkyung、井田智章、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第22回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] CD3鎖を標的とした超硫黄分子によるTCRシグナルを介した免疫応答制御2022
- Author(s)
  守田匡伸、山田充啓、佐々木優作、井田智章、松永哲郎、高田剛、渡部聡、稲葉謙次、石井直人、杉浦久敏、本橋ほづみ、赤池孝章
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] T細胞受容体シグナル(TCR)伝達を介した超硫黄分子による免疫応答制御2022
- Author(s)
  守田匡伸、山田充啓、佐々木優作、井田智章、松永哲郎、高田剛、渡部聡、稲葉謙次、石井直人、杉浦久敏、本橋ほづみ、赤池孝章
- Organizer
  第32回生体防御学会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] Supersulfides Catalyze Nitric Oxide Metabolism via Glutathione-coupled Electron Transfer from Formaldehyde2022
- Author(s)
  Masanobu Morita, Tetsuro Matsunaga, Shingo Kasamatsu, Akira Nishimura, Md. Morshedul Alam, Kakeru Shimoda, Akiyuki Nishimura, Seiryo Ogata, Minkyung Jung, Tomoaki Ida, Motohiro Nishida, Hozumi Motohashi, Takaaki Akaike
- Organizer
  Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] 超硫黄触媒酵素としてのアルコールデヒドロゲナーゼ5（ADH5）の NOシグナル制御メカニズム2022
- Author(s)
  守田匡伸、松永哲郎、笠松真吾、西村明、Md. Morshedul Alam、下田翔、井田智章、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第75回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] Sulfide:quinone oxidoreductase is essential for sulfur respiration in mitochondria2022
- Author(s)
  Masanobu Morita, Tetsuro Matsunaga, Tomoaki Ida, Tomohiro Tanaka, Motohiro Nishida, Hozumi Motohashi, Takaaki Akaike
- Organizer
  6th World Congress on Hydrogen Sulfide in Biology & Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] T細胞受容体 (TCR)/CD3複合体を標的とした超硫黄分子による免疫応答制御2021
- Author(s)
  守田匡伸、山田充啓、佐々木優作、井田智章、松永哲郎、高田剛、渡部聡、稲葉謙次、石井直人、杉浦久敏、本橋ほづみ、赤池孝章
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] カーボンナノチューブによる毒性発現機構2021
- Author(s)
  山口慎一朗，守田匡伸，伊藤文哉，謝祺琳，豊國伸哉，中山勝文
- Organizer
  第48回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03880
[Presentation] カーボンナノチューブ受容体の同定2021
- Author(s)
  山口慎一朗，守田匡伸，伊藤文哉，謝祺琳，豊國伸哉，中山勝文
- Organizer
  第28回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-19H03880
[Presentation] T細胞受容体シグナル(TCR)伝達を介した超硫黄分子による免疫応答制御2021
- Author(s)
  守田匡伸、山田充啓、佐々木優作、井田智章、松永哲郎、高田剛、渡部聡、稲葉謙次、石井直人、杉浦久敏、本橋ほづみ、赤池孝章
- Organizer
  第32回生体防御学会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] Longevity is dependent on sulfide:quinone oxidoreductase mediated energy metabolism in fission yeast2021
- Author(s)
  Masanobu Morita, Akira Nishimura, Tomoaki Ida, Minkyung Jung, Tetsuro Matsunaga, Tsuyoshi Takata, Hozumi Motohashi, Takaaki Akaike
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] 酵母におけるsulfide:quinone oxidoreductase を介したエネルギー代謝による寿命制御2021
- Author(s)
  守田匡伸、西村明、井田智章、ジョンミンギョン、松永哲郎、高田剛、本橋ほづみ、赤池孝章
- Organizer
  第94回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] 硫化水素キノン酸化還元酵素（SQR）を介した超硫黄分子による種横断的なミトコンドリア硫黄呼吸2021
- Author(s)
  守田匡伸、西村明、井田智章、松永哲郎、高田剛、ジョンミンキョン、田中智弘、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第74回日本酸化ストレス学会/第21回日本NO学会　合同学術集会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] 活性硫黄分子によるインフルエンザウイルス肺炎の予防・治療法の開発2020
- Author(s)
  守田匡伸、滝田克也、佐野寛仁、杉浦久敏、市川朋宏、沼倉忠久、井田智章、山田充啓、京極自彦、松永哲郎、本橋ほづみ、赤池孝章
- Organizer
  第31回生体防御学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] 硫化水素キノン酸化還元酵素 (SQR)を介した超硫黄分子による種横断的なミトコンドリア硫黄呼吸2020
- Author(s)
  守田匡伸、西村明、井田智章、松永哲郎、高田剛、ジョンミンギョン、田中智弘、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第73回日本酸化ストレス学会／第20回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] ゲノム編集によるミトコンドリア/イオウ呼吸選択的硫化水素キノン酸化還元酵素 (SQR)欠損マウスの開発2019
- Author(s)
  守田匡伸、井田智章、田中智弘、松永哲郎、西村明、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] ミトコンドリア選択的硫化水素キノン還元酵素(SQR)欠損マウスは致死性のイオウ呼吸不全を示す2019
- Author(s)
  守田匡伸、井田智章、田中智弘、松永哲郎、西村明、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第92回生化学学会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] 活性イオウ分子によるエネルギー代謝制御2019
- Author(s)
  守田匡伸、井田智章、西村明、田中智弘、松永哲郎、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第7回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] ミトコンドリア・イオウ呼吸選択的硫化水素キノン酸化還元酵素 (SQR)欠損マウスの開発と機能解析2019
- Author(s)
  守田匡伸、井田智章、田中智弘、松永哲郎、西村明、西田基宏、本橋ほづみ、赤池孝章
- Organizer
  第72回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] ゲノム編集で明らかになった活性イオウ分子によるエネルギー代謝制御2019
- Author(s)
  守田匡伸
- Organizer
  実験動物セミナー第３０回研究成果発表会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] Cysteinyl-tRNA synthetase (CARS) contributes to sulfur respiration and protection against chronic obstructive pulmonary disease (COPD)2019
- Author(s)
  M. Morita, T. Akaike, T. Matsunaga, T. Ida, A. Nishimura, H. Sano, T. Ichikawa, H. Sugiura, M. Ichinose , M. Motohashi
- Organizer
  Oxygen Radicals Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] Mitochondria-specific SQR knock-out mice cause lethal impairment of sulfur respiration2019
- Author(s)
  Masanobu Morita, Tomoaki Ida, Tomohiro Tanaka, Tetsuro Matsunaga, Akira Nishimura, Motohiro Nishida, Hozumi Motohashi, Takaaki Akaike
- Organizer
  第１回硫黄代謝の医学生物学に関する国際会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07341
[Presentation] Characterization of three major cysteine sensors of Keap1 in stress response.2016
- Author(s)
  T. Suzuki, R. Saito, K. Hiramoto, S. Asami, E. Naganuma, H. Suda, T. Iso, H. Yamamoto, M. Morita, L. Baird, Y. Furusawa, T. Negishi, M. Ichinose, M. Yamamoto
- Organizer
  The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-05-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02815

1. Masafumi Nakayama (20453582)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 井田智章 (70570406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. SATOH Hironori (90407479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MORIGUCHI Takashi (10447253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KATOH Yasutake (40397914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAGASHIMA Takeshi (80443000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAIGUSA Daisuke (90545237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUMOTO Mitsuyo (80400448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IKEHATA Hironobu (90250737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. Taniguchi Noboru (20626866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 鈴木隆史 (70508308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 森永秀孝 (70444792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中島利博 (90260752)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森本展行 (00313263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 松永哲郎 (00723206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. 石井直人 (60291267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 河部剛史 (50834652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 宗孝紀 (60294964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. HIRAMOTO Keiichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. NAGANUMA Eriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
24. 平野育生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 清水律子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 長谷川敦史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morita Masanobu 守田 匡伸

MORITA Masanobu 守田 匡伸

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超硫黄分子の代謝制御メカニズムの解明Principal Investigator

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Functional analysis of sulfur metabolism and respiratory system: genome editing and energy metabolism analysisPrincipal Investigator

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differentiation and reprogramming regulated by oxidative stressPrincipal Investigator

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Oxidative stress signal function in stem cells via keap1-Nrf2 systemPrincipal Investigator

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[Book] 光と生命の事典2016

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[Book] Survival strategy and disease pathogenesis according to the Nrf2-small Maf heterodimer2011

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[Journal Article] Supersulfides support bone growth by promoting chondrocyte proliferation in the growth plates2024

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Morita Masanobu 守田匡伸

MORITA Masanobu 守田匡伸