HITOMI YUKI 人見祐基

… Alternative Names

HITOMI Yuki 人見祐基

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Researcher Number	10525819
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立国際医療研究所, 室長
Affiliation (based on the past Project Information) *help	2022 – 2023: 国立研究開発法人国立国際医療研究センター, 研究所, 疾患ゲノム研究室長 2019 – 2021: 星薬科大学, 薬学部, 特任講師 2015 – 2018: 東京大学, 大学院医学系研究科(医学部), 助教 2014 – 2016: 東京大学, 医学(系)研究科(研究院), 助教 2014: 東京大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related / Medium-sized Section 53:Organ-based internal medicine and related fields / Biological Sciences
Keywords	Principal Investigator 原発性胆汁性胆管炎（PBC） / ゲノムワイド関連解析（GWAS） / ゲノム編集 / 疾患感受性遺伝子領域 / 疾患感受性遺伝子 / 遺伝子多型 / 原発性胆汁性胆管炎 / ゲノムワイド関連解析 / post-GWAS / PTPN2 … More / CD58 / Post-GWAS研究 / PBC / PBC感受性遺伝子領域 / 免疫学 / 内科 / ゲノム / 遺伝子 / 遺伝学 / 日本人PBC感受性遺伝子領域 / 原発性胆汁性肝硬変 … More Except Principal Investigator 疾患感受性遺伝子 / ゲノムワイド関連解析 / 原発性胆汁性胆管炎 / 統合解析 / トランスクリプトーム / 分子標的 / 疾患発症経路 / 治療標的 / 臨床ゲノム解析 / 疾患関連遺伝子 / ネガティブフィードバック機構 / IFNG / PTPN2 / 器官システム内科学 / 腎臓学 / フィンランド型先天性ネフローゼ症候群 / ネフリン / ステロイド感受性ネフローゼ症候群 / 網羅的遺伝子発現解析 / GWAS / 原発性胆汁性肝硬変 / 肝臓学 / 病型分類 / 予後予測 / 免疫遺伝 / 自己免疫 / MHC / HLA / 主要組織適合性抗原(MHC) / ヒト白血球抗原(HLA) Less

原発性胆汁性胆管炎の新たな病態解明と治療標的の同定を目指した臨床ゲノム解析
- Principal Investigator
  
  中村稔
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
新たなpost-GWAS方法論による原発性胆汁性胆管炎の発症機序の全貌解明Principal Investigator
- Principal Investigator
  
  人見祐基
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Center for Global Health and Medicine
Molecular genetic analysis to elucidate the pathogenesis of primary biliary cholangitis and develop personalized medicine.Principal Investigator
- Principal Investigator
  
  Hitomi Yuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Hoshi University
Joint International Research for identification of disease-susceptible genes and drug-sensitive genes in childhood nephrotic syndrome
- Principal Investigator
  
  IIJIMA KAZUMOTO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Kobe University
Clarification of the molecular mechanisms of pathogenesis caused by PBC susceptibility genes and their application to personalized medicinePrincipal Investigator
- Principal Investigator
  
  Hitomi Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Hoshi University
  The University of Tokyo
GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitis
- Principal Investigator
  
  Nakamura Minoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
Clarification of the molecular mechanisms of pathogenesis caused by PBC susceptibility polymorphismsPrincipal Investigator
- Principal Investigator
  
  Hitomi Yuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Analysis of disease-pathways and molecular targets by disease-susceptibility genes in primary biliary cholangitis
- Principal Investigator
  
  Nakamura Minoru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
Diversity in HLA heterodimers
- Principal Investigator
  
  MIYADERA Hiroko
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Research Institute, International Medical Center of Japan
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation

[Journal Article] A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis2024
- Author(s)
  Hitomi Yuki、Ueno Kazuko、Aiba Yoshihiro、et al.
- Journal Title
  
  Hepatology
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08065
[Journal Article] A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis.2024
- Author(s)
  Hitomi Y, Ueno K, Aiba Y, et al.
- Journal Title
  
  Hepatology
  
  Volume: in press Issue: 4 Pages: 776-790
- DOI
  10.1097/hep.0000000000000894
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07366
[Journal Article] The Genetics of Primary Biliary Cholangitis: A GWAS and Post-GWAS Update.2023
- Author(s)
  Hitomi Y, Nakamura M.
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 2 Pages: 405-405
- DOI
  10.3390/genes14020405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08065, KAKENHI-PROJECT-23K07366
[Journal Article] rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases2023
- Author(s)
  Hitomi Yuki、Ueno Kazuko、Aiba Yoshihiro、Nishida Nao、Kawai Yosuke、Kawashima Minae、Khor Seik-Soon、Takada Sanami、Iwabuchi Chisato、Nagasaki Masao、Tokunaga Katsushi、Nakamura Minoru
- Journal Title
  
  Human Genetics
  
  Volume: 143 Issue: 1 Pages: 19-33
- DOI
  10.1007/s00439-023-02617-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08065, KAKENHI-PROJECT-23K07366, KAKENHI-PROJECT-23K07471
[Journal Article] Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population2023
- Author(s)
  Khor Seik-Soon、Ueno Kazuko、Nishida Nao、Kawashima Minae、Kawai Yosuke、Aiba Yoshihiro、Hitomi Yuki、Nagasaki Masao、Nakamura Minoru、Tokunaga Katsushi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1151502-1151502
- DOI
  10.3389/fimmu.2023.1151502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08065, KAKENHI-PROJECT-23K07366, KAKENHI-PROJECT-23K07471
[Journal Article] rs9459874 and rs1012656 in CCR6/FGFR1OP confer susceptibility to primary biliary cholangitis2022
- Author(s)
  Hitomi Yuki、Aiba Yoshihiro、Ueno Kazuko、Nishida Nao、Kawai Yosuke、Kawashima Minae、Yasunami Michio、Gervais Olivier、Ito Masahiro、Cordell Heather J.、Mells George F.、Nagasaki Masao、Tokunaga Katsushi、Tsuiji Makoto、Nakamura Minoru
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 126 Pages: 102775-102775
- DOI
  10.1016/j.jaut.2021.102775
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K07471, KAKENHI-PROJECT-19K08413, KAKENHI-PROJECT-20K08370
[Journal Article] rs2013278 in the multiple immunological-trait susceptibility locus CD28 regulates the production of non-functional splicing isoforms.2022
- Author(s)
  Yuki Hitomi, Yoshihiro Aiba, Kazuko Ueno, Nao Nishida, Yosuke Kawai, Minae Kawashima, Makoto Tsuiji, Chisato Iwabuchi, Sanami Takada, Noriko Miyake, Masao Nagasaki, Katsushi Tokunaga, Minoru Nakamura
- Journal Title
  
  Human genomics
  
  Volume: 16(1) Issue: 1 Pages: 46-46
- DOI
  10.1186/s40246-022-00419-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06603, KAKENHI-PROJECT-22K08065
[Journal Article] Regional heritability mapping identifies several novel loci (STAT4, 3 ULK4, and KCNH5) for primary biliary cholangitis in the Japanese 4 population2021
- Author(s)
  Olivier Gervais, Kazuko Ueno, Yosuke Kawai, Yuki Hitomi, Yoshihiro Aiba, Mayumi Ueta, Minoru Nakamura, Katsushi Tokunaga & Masao Nagasaki
- Journal Title
  
  European Journal of Human Genetics
  
  Volume: － Issue: 8 Pages: 1282-1291
- DOI
  10.1038/s41431-021-00854-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08370, KAKENHI-PROJECT-19K08413
[Journal Article] rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis2021
- Author(s)
  Hitomi Yuki、Aiba Yoshihiro、Kawai Yosuke、Kojima Kaname、Ueno Kazuko、Nishida Nao、Kawashima Minae、Gervais Olivier、Khor Seik-Soon、Nagasaki Masao、Tokunaga Katsushi、Nakamura Minoru、Tsuiji Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 4557-4557
- DOI
  10.1038/s41598-021-84042-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07334, KAKENHI-PROJECT-19K08413
[Journal Article] An international genome-wide meta-analysis of primary biliary cholangitis: novel risk loci and a hierarchy of candidate drugs.2021
- Author(s)
  Heather J. Cordell, James J. Fryett, Kazuko Ueno, Rebecca Darlay, Yoshihiro Aiba, Yuki Hitomi, Minae Kawashima, Nao Nishida, Seik-Soon Khor, Olivier Gervais, et al.
- Journal Title
  
  Journal of Hepatology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08413
[Journal Article] Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome2020
- Author(s)
  Jia Xiaoyuan、Yamamura Tomohiko、et al.
- Journal Title
  
  Kidney International
  
  Volume: 98 Issue: 5 Pages: 1308-1322
- DOI
  10.1016/j.kint.2020.05.029
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-19K08726, KAKENHI-PROJECT-20K08370, KAKENHI-PROJECT-20K16892, KAKENHI-PROJECT-18KK0244, KAKENHI-PROJECT-20H03698
[Journal Article] Genomic heritabilities and correlations of 17 traits related to obesity and associated conditions in the Japanese population2020
- Author(s)
  Olivier Gervais, Kazuko Ueno, Yosuke Kawai, Yuki Hitomi, Kazuharu Misawa, Shunsuke Teraguchi, Yen-Yen Wang, Katsushi Tokunaga, Masao Nagasaki
- Journal Title
  
  G3: Genes|Genomes|Genetics
  
  Volume: ー Issue: 7 Pages: 2221-2228
- DOI
  10.1534/g3.120.401242
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14757, KAKENHI-PROJECT-19K08413
[Journal Article] Integrated GWAS and mRNA Microarray Analysis Identified IFNG and CD40L as the Central Upstream Regulators in Primary Biliary Cholangitis2020
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, et al.
- Journal Title
  
  Hepatology Communications
  
  Volume: 4 Issue: 5 Pages: 724
- DOI
  10.1002/hep4.1497
- URL
  https://localhost/en/publications/e40c56eb-b36e-40c5-9411-8cd08a333694
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08413, KAKENHI-PROJECT-17H04168, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-17K09449, KAKENHI-PROJECT-17K15924
[Journal Article] POGLUT1, the putative effector gene driven by rs2293370 in primary biliary cholangitis susceptibility locus chromosome 3q13.332019
- Author(s)
  Hitomi, Y. Ueno, K. Kawai, Y. Nishida, N. , Umemura, T. et al
- Journal Title
  
  Sci Rep
  
  Volume: 9 Issue: 1 Pages: 102-102
- DOI
  10.1038/s41598-018-36490-1
- NAID
  120006715480
- URL
  https://localhost/en/publications/33df0dd9-d3e0-48ea-8c1e-c423549e0f32
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09416, KAKENHI-PROJECT-17K15924, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-17H04168, KAKENHI-PROJECT-17K09448, KAKENHI-PROJECT-17K09449
[Journal Article] NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants.2018
- Author(s)
  Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol
  
  Volume: 7 Issue: 3 Pages: 515-532
- DOI
  10.1016/j.jcmgh.2018.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15924, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-17H04168, KAKENHI-PROJECT-17K09449
[Journal Article] Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis2018
- Author(s)
  Aiba Yoshihiro、Harada Kenichi、Ito Masahiro、Suematsu Takashi、Aishima Shinichi、Hitomi Yuki、Nishida Nao、Kawashima Minae、Takatsuki Mitsuhisa、Eguchi Susumu、Shimoda Shinji、Nakamura Hitomi、Komori Atsumasa、Abiru Seigo、Nagaoka Shinya、Migita Kiyoshi、Yatsuhashi Hiroshi、Tokunaga Katsushi、Nakamura Minoru
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 11808-11808
- DOI
  10.1038/s41598-018-30146-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09449, KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-17H04169
[Journal Article] Strong Association of the HLA-DR/DQ Locus with Childhood Steroid-Sensitive Nephrotic Syndrome in the Japanese Population.2018
- Author(s)
  Jia X, Horinouchi T, Hitomi Y, Shono A, Khor SS, Omae Y, Kojima K, Kawai Y, Nagasaki M, Kaku Y, Okamoto T, Ohwada Y, Ohta K, Okuda Y, Fujimaru R, Hatae K, Kumagai N, Sawanobori E, Nakazato H, Ohtsuka Y, Nakanishi K, Shima Y, Tanaka R, Ashida A, Kamei K, Ishikura K, Nozu K, Tokunaga K, Iijima K
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 29 Issue: 8 Pages: 2189-2199
- DOI
  10.1681/asn.2017080859
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07799, KAKENHI-PROJECT-18KK0244, KAKENHI-PLANNED-18H05511, KAKENHI-PROJECT-15K09694, KAKENHI-PROJECT-16K10066
[Journal Article] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population2018
- Author(s)
  Nishida Nao、Aiba Yoshihiro、Hitomi Yuki、Nagasaki Masao、Tokunaga Katsushi、Nakamura Minoru et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8071-8071
- DOI
  10.1038/s41598-018-26369-6
- NAID
  120006551764
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09449, KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-17H04169
[Journal Article] Cathepsin Z variants are associated with progression to end-stage hepatic failure in Japanese patients with primary biliary cholangitis.2017
- Author(s)
  Nishida N, Aiba Y, Kawashima M, Hitomi Y, Kojima K, Komori A, Nagasaki M,Tokunaga K, Nakamura M
- Journal Title
  
  J Hepatol
  
  Volume: 66(1, Suppl)
- Data Source
  KAKENHI-PROJECT-17H04169
[Journal Article] Genome-wide association studies identify PRKCB as a novel genetic susceptibility locus for primary biliary cholangitis in the Japanese population.2017
- Author(s)
  Kawashima M, Honda M, Nakamura M. et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: - Pages: 650-659
- DOI
  10.1093/hmg/ddw406
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04809, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26460416, KAKENHI-PROJECT-26460996, KAKENHI-PROJECT-16K15426, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-16K21069, KAKENHI-PROJECT-17H04058, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-16H05283, KAKENHI-PROJECT-15K19357
[Journal Article] Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population2017
- Author(s)
  Yasunami Michio、Nakamura Hitomi、Tokunaga Katsushi、Kawashima Minae、Nishida Nao、Hitomi Yuki、Nakamura Minoru
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 11093-11093
- DOI
  10.1038/s41598-017-11148-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15924, KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314
[Journal Article] Identification of the functional variant driving ORMDL3 and GSDMB expression in human chromosome 17q12-21 in primary biliary cholangitis2017
- Author(s)
  Hitomi Yuki、Kojima Kaname、Kawashima Minae、Kawai Yosuke、Nishida Nao、Aiba Yoshihiro、Yasunami Michio、Nagasaki Masao、Nakamura Minoru、Tokunaga Katsushi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 2904-2904
- DOI
  10.1038/s41598-017-03067-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293076, KAKENHI-PROJECT-17H04169, KAKENHI-PROJECT-15K06908
[Journal Article] Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.2016
- Author(s)
  Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(6) Issue: 1 Pages: 31429-31429
- DOI
  10.1038/srep31429
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314
[Journal Article] Disease susceptibility genes shared by primary biliary cirrhosis and Crohn’s disease in the Japanese population2015
- Author(s)
  Yoshihiro Aiba, Keiko Yamazaki, Nao Nishida, Minae Kawashima, Yuki Hitomi, Hitomi Nakamura, Atsumasa Komori, Yuta Fuyuno, Atsushi Takahashi, Takaaki Kawaguchi, Masakazu Takazoe, Yasuo Suzuki, Satoshi Motoya Toshiyuki Matsui Motohiro Esaki, Takayuki Matsumoto, Michiaki Kubo, Katsushi Tokunaga, Minoru Nakamura
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 印刷中 Issue: 9 Pages: 525-531
- DOI
  10.1038/jhg.2015.59
- NAID
  40020589506
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-15K19357, KAKENHI-PROJECT-26293180, KAKENHI-PROJECT-26293181
[Journal Article] Human primary biliary cirrhosis-susceptible allele of rs4979462 enhances TNFSF15 expression by binding NF-1.2015
- Author(s)
  Hitomi Y, Kawashima M, Aiba Y, Nishida N, Matsuhashi M, Okazaki H, Nakamura M, Tokunaga K
- Journal Title
  
  Human Genetics
  
  Volume: 印刷中 Issue: 7 Pages: 737-747
- DOI
  10.1007/s00439-015-1556-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-15K06908, KAKENHI-PROJECT-15K19314, KAKENHI-PROJECT-15K19357, KAKENHI-PROJECT-26293181
[Presentation] A gene expression regulatory variant in CD58 confers susceptibility to human autoimmune diseases2024
- Author(s)
  人見祐基、相葉佳洋、中村稔
- Organizer
  第52回日本免疫学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] Identification of a gene expression regulatory variant in autoimmune diseases-susceptibility locus CD58.2023
- Author(s)
  Hitomi Y, Ueno K, Aiba Y, Nishida N, Kawai Y, Kawashima M, Khor SS, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  Human Genetics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 抗原提示補助シグナル分子の遺伝的バリアントに起因する自己免疫疾患感受性の分子機序の解明2023
- Author(s)
  人見祐基、植野和子、相葉佳洋、西田奈央、河合洋介、川嶋実苗、Knor SS、長﨑正朗、徳永勝士、中村稔
- Organizer
  第31回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 原発性胆汁性胆管炎のトランスクリプトームデータを用いた治療標的遺伝子の探索2023
- Author(s)
  相葉佳洋、植野和子、人見祐基、伊東正博、小森敦正、中村稔
- Organizer
  第60回日本消化器免疫学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] シンポジウム2; 消化器診療へのゲノムワイド研究のインパクト, 国際メタ GWAS によって同定された東アジア人特異的な原発性胆汁性胆管炎（PBC）感受性遺伝子領域に起因する発症機序の解明.2023
- Author(s)
  人見祐基、中村　稔
- Organizer
  第109回日本消化器病学会総会.　長崎 2023.4.7
- Data Source
  KAKENHI-PROJECT-23K07366
[Presentation] 自己免疫疾患感受性遺伝子に起因する発症機序の解明におけるCRISPR/Cas9の活用2023
- Author(s)
  人見祐基、植野和子、相葉佳洋、西田奈央、川嶋実苗、Khor SS、長崎正朗、徳永勝士、中村稔
- Organizer
  第8回日本ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 国際メタGWASによって同定された原発性胆汁性胆管炎（PBC）感受性遺伝子領域CD28に由来する発症機序の解明2023
- Author(s)
  人見祐基、相葉佳洋、西田奈央、中村稔
- Organizer
  第59回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population.2023
- Author(s)
  Knor SS、植野和子、西田奈央、川嶋実苗、河合洋介、相葉佳洋、人見祐基、長﨑正朗、中村稔、徳永勝士
- Organizer
  第6回関東HLA研究会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 国際メタGWASによって同定された東アジア人特異的な原発性胆汁性胆管炎（PBC）感受性遺伝子領域に起因する発症機序の解明2023
- Author(s)
  人見祐基、中村稔
- Organizer
  第109回日本消化器病学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 原発性胆汁性胆管炎の疾患感受性遺伝子POU2AF1が制御する遺伝子の検討2022
- Author(s)
  相葉佳洋、植野和子、人見祐基、西田奈央、小森敦正、阿比留正剛、長岡進矢、八橋弘、中村稔
- Organizer
  第58回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 国際メタGWASによって同定された原発性胆汁性胆管炎（PBC）感受性遺伝子領域CCR6/FGFR1OPに由来する発症機序の解明2022
- Author(s)
  人見祐基、相葉佳洋、中村稔
- Organizer
  第58回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] 様々な免疫形質と関連するCD28領域におけるスプライシング制御バリアントの同定2022
- Author(s)
  人見祐基、相葉佳洋、植野和子、西田奈央、河合洋介、川嶋実苗、築地信、岩渕千里、高田紗奈美、三宅紀子、長﨑正朗、徳永勝士、中村稔
- Organizer
  第67回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-22K08065
[Presentation] Identification of seven primary functional variants in primary biliary cholangitis susceptibility loci in the Japanese population.2021
- Author(s)
  Hitomi Y, Aiba Y, Ueno K, Kawai Y, Nishida N, Kawashima M, Gervais O, Nagasaki M, Tokunaga K, Tsuiji M, Nakamura M.
- Organizer
  American Society of Histocompatibility and Immunogenetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] COLCA1 and COLCA2, the effector genes driven by rs1944919 in primary biliary cholangitis (PBC) susceptibility locus chromosome 11q23.1 in the Japanese population.2021
- Author(s)
  Hitomi Y, Aiba Y, Kawai Y, Kojima K, Ueno K, Nishida N, Kawashima M, Gervais O, Khor SS, Nagasaki M, Tokunaga K, Tsuiji M, Nakamura M.
- Organizer
  APASL single topic conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] Applying the regional heritability mapping method to primary biliary cholangitis in the Japanese population.2021
- Author(s)
  Gervais O, Ueno K, Kawai Y, Hitomi Y, Aiba Y, Ueta M, Nakamura M, Tokunaga K, Nagasaki M
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] Transcriptome and GWAS identified rs2238678 as a critical SNP for eosinophilia in primary biliary cholangitis.2021
- Author(s)
  Ueno K, Hitomi Y, Aiba Y, Gervais O, Kawai Y, Khor SS, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 原発性胆汁性胆管炎における疾患感受性遺伝子POU2AF1とその関連遺伝子の解析2021
- Author(s)
  相葉佳洋, 植野和子, 人見祐基, 西田奈央, 下田慎司, 小森敦正, 橋元悟, 戸次鎮宗, 阿比留正剛, 長岡進矢, 八橋弘, 中村稔
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 原発性胆汁性胆管炎（PBC）感受性遺伝子CCR6/FGFR1OPにおけるprimary functional variantsの同定2021
- Author(s)
  人見祐基、相葉佳洋、植野和子、西田奈央、河合洋介、川嶋実苗、安波道朗、Gervais O、長﨑正朗、徳永勝士、築地信、中村稔
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene CCR6/FGFR1OP.2021
- Author(s)
  人見祐基、相葉佳洋、築地信、中村稔
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] rs1944919 on human chromosome 11q23.1 and its effector genes COLCA1 and COLCA2 confer susceptibility to primary biliary cholangitis.2021
- Author(s)
  Hitomi Y, Aiba Y, Kawai Y, Kojima K, Ueno K, Nishida N, Kawashima M, Gervais O, Khor SS, Nagasaki M, Tokunaga K, Tsuiji M, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] COLCA1/COLCA2, the effector genes in primary biliary cholangitis susceptibility locus chromosome 11q23.1.2020
- Author(s)
  人見祐基、相葉佳洋、河合洋介、小島要、植野和子、西田奈央、川嶋実苗、Garveis O、Khor SS、長﨑正朗、徳永勝士、中村稔、築地信
- Organizer
  第65回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] The analysis of POU2AF1 and its related molecules in the pathogenesis of primary biliary cholangitis by using GWAS and transcriptome datasets.2020
- Author(s)
  Aiba Y, Ueno K, Hitomi Y, Gervais O, Kawai Y, Kawashima M, Nishida N, Komori A, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域11番染色体長腕23.1に位置するcausal variantおよびエフェクター遺伝子の同定2020
- Author(s)
  人見祐基、中村稔
- Organizer
  第56回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 原発性胆汁性胆管炎に関与する遺伝子の共発現ネットワーク解析2020
- Author(s)
  相葉佳洋、植野和子、人見祐基、小森敦正、橋元悟、戸次鎮宗、阿比留正剛、長岡進矢、八橋弘、中村稔
- Organizer
  第56回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] Transcriptome and GWAS identified androgen receptor as a central regulator for eosinophilia in primary biliary cholangitis.2020
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, Kawai Y, Khor SS, Gervais O, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] POGLUT1, The Effector Gene Driven by rs2293370 in Primary Biliary Cholangitis (PBC) Susceptibility Locus Chromosome 3q13.33 in The Japanese Population2019
- Author(s)
  Hitomi Y, Ueno K, Kayai Y, et al.
- Organizer
  APASL STC Tokyo 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Integrated analysis of GWAS and mRNA expression array identified IFNG and CD40L as the most significant upstream-regulators in primary biliary cholangitis.2019
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, Shimoda S, Gervais O, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 遺伝性腎疾患に対するプレシジョンメデイスン　小児ステロイド感受性ネフローゼ症候群の疾患感受性遺伝子2019
- Author(s)
  飯島一誠、 Jia Xiaoyuan,、山村智彦、人見祐基、長野智那、堀之内智子、野津寛大、徳永勝士
- Organizer
  第54回日本小児腎臓病学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0244
[Presentation] POGLUT1, the effector gene driven by rs2293370 in primary biliary cholangitis (PBC) susceptibility locus chromosome 3q13.33 in the Japanese population.2019
- Author(s)
  Hitomi Y, Ueno K, Kawai Y, Nishida N, Kojima K, Kawashima M, Aiba Y, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, nakamura M, PBC-GWAS consortium in Japan.
- Organizer
  APASL single topic conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Pathway-Analysis Using Datasets of GWAS and mRNA Expression Array Identified IFNG as the Most Significant Upstream-Regulator in Primary Biliary Cholangitis.2019
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, Shimoda S, Tanaka A, Gervais O, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, nakamura M, PBC-GWAS consortium in Japan.
- Organizer
  APASL single topic conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 原発性胆汁性胆管炎（PBC）感受性遺伝子領域に起因する発症機序の解明におけるゲノム編集技術の応用2019
- Author(s)
  人見祐基、河合洋介、植野和子、西田奈央、川嶋実苗、相葉佳洋、Olivier Gervais、Seik-Soon Khor、築地信、長﨑正朗、中村稔、徳永勝士
- Organizer
  第64回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域3番染色体長腕13.33に位置するcausal variantおよびエフェクター遺伝子 POGLUT1 の同定2019
- Author(s)
  人見祐基、中村稔
- Organizer
  第55回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域3番染色体長腕13.33に位置するcausal variantおよびエフェクター遺伝子 POGLUT1 の同定2019
- Author(s)
  人見祐基、中村稔
- Organizer
  第55回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Pathway-Analysis Using Datasets of GWAS and mRNA Expression Array Identified IFNG as the Most Significant Upstream-Regulator in Primary Biliary Cholangitis.2019
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, et al
- Organizer
  APASL STC Tokyo 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Role of PRKCB in the development of primary biliary cholangitis.2019
- Author(s)
  Aiba Y, Hitomi Y, Ueno K, et al.
- Organizer
  The 48th Annual Meeting of the Japanese Society of Immunology（第48回日本免疫学会学術集会）.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 原発性胆汁性胆管炎（PBC）感受性遺伝子領域に起因する発症機序の解明におけるゲノム編集技術の応用2019
- Author(s)
  人見祐基、河合洋介、植野和子、西田奈央、川嶋実苗、相葉佳洋、Olivier Gervais、Seik-Soon Khor、築地信、長﨑正朗、中村稔、徳永勝士
- Organizer
  第64回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 原発性胆汁性胆管炎（PBC）感受性遺伝子領域を対象とした機能的遺伝子多型（causal variant）の同定2019
- Author(s)
  人見祐基、河合洋介、植野和子、西田奈央、川嶋実苗、相葉佳洋、築地信、長﨑正朗、中村稔、徳永勝士
- Organizer
  第28回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 原発性胆汁性胆管炎の肝組織網羅的遺伝子発現データを用いた疾患感受性遺伝子ならびに疾患関連pathwayの解析2019
- Author(s)
  相葉佳洋、西田奈央, 人見祐基, 小森敦正, 八橋弘, 中村稔.
- Organizer
  第55回日本肝臓学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] expression array identified IFNG and CD40L as the most significant upstream-regulators in primary biliary cholangitis.2019
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, Shimoda S, Gervais O, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] 原発性胆汁性胆管炎（PBC）感受性遺伝子領域を対象とした機能的遺伝子多型（causal variant）の同定2019
- Author(s)
  人見祐基、河合洋介、植野和子、西田奈央、川嶋実苗、相葉佳洋、築地信、長﨑正朗、中村稔、徳永勝士
- Organizer
  第28回日本組織適合性学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] Role of PRKCB in the development of primary biliarycholangitis.2019
- Author(s)
  相葉佳洋、人見祐基、植野和子、中村稔
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-19K08413
[Presentation] Role of PRKCB in the development of primary biliarycholangitis2019
- Author(s)
  相葉佳洋、人見祐基、植野和子、中村稔
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Integrated analysis of GWAS and mRNA expression array identified IFNG and CD40L as the most significant upstream-regulators in primary biliary cholangitis.2019
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, et al
- Organizer
  The 69th Annual Meeting of The American Society of Human Genetics (ASHG 2019).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] The role of PRKCB in the development of primary biliary cholangitis.2019
- Author(s)
  Aiba Y, Ueno K, Hitomi Y, Kawashima M, Nishida N, Kawai Y, Komori A, Yatsuhashi H, Nagasaki M, Tokunaga K, Nakamura M and PBC-GWAS consortium in Japan.
- Organizer
  American Association for the study of liver diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Pathway-Analysis Using Datasets of GWAS and mRNA Expression Array Identified IFNG as the Most Significant Upstream-Regulator in Primary Biliary Cholangitis2019
- Author(s)
  Ueno K, Aiba Y, Hitomi Y, Shimoda S, Tanaka A, Gervais O, Kawai Y, Kawashima M, Nishida N, Kojima K, Nagasaki M, Tokunaga K, nakamura M, PBC-GWAS consortium in Japan.
- Organizer
  APASL single topic conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域3番染色体長腕13.33に位置するcausal variantおよびエフェクター遺伝子POGLUT1の同定.2019
- Author(s)
  人見祐基, 中村　稔
- Organizer
  第55回日本肝臓学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] The role of PRKCB in the development of primary biliary cholangitis2019
- Author(s)
  Aiba Y, Ueno K, Hitomi Y, et al
- Organizer
  AASLD THE LIVER MEETING 2019.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 原発性胆汁性胆管炎（PBC）の疾患感受性遺伝子領域3q13.33におけるeffector遺伝子POGLUT1の同定2018
- Author(s)
  人見祐基
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Genotype imputation of structural polymorphism with whole genome sequencing based haplotypes reference panel.2018
- Author(s)
  Kawai Y, Mimori T, Ueno K, Hitomi Y, Gervais O, Khor SS, Kawashima M, Nishida N, Nakamura M, Nagasaki M, Tokunaga K
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Identification of POGLUT1 as the effector gene in primary biliary cholangitis susceptibility locus chromosome 3q13.332018
- Author(s)
  人見祐基、植野和子、河合洋介、西田奈央、小島要、川嶋実苗、相葉佳洋、長崎正朗、徳永勝士、中村稔
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] ゲノムワイド関連解析による小児特発性ネフローゼ症候群のrisk haplotype同定2018
- Author(s)
  堀之内　智子、Xiaoyuan Jia、人見　祐基、石倉　健司、亀井　宏一、濱田　陸、郭　義胤、藤丸　季可、岡本　孝之、大和田　葉子、田中　亮二郎、後藤　芳充、貝籐　裕史、野津　寛大、徳永　勝士、飯島　一誠
- Organizer
  第53回小児腎臓病学会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0244
[Presentation] Short tandem repeat (STR) profile of pentanucleotide repeats and high-resolution STR typing solution for the Japanese population2018
- Author(s)
  Saito M, Hirata S, Kojima K, Misawa K, Mimori T, Gervais O, Kawai Y, Hitomi Y, Tokunaga K, Nakamura M, Nagasaki M
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Genome-wide meta-analysis and functional analysis identified POGLUT1 as the effector gene driven by rs2293370 in primary biliary cholangitis (PBC) susceptibility locus chromosome 3q13.33 in the Japanese population.2018
- Author(s)
  Hitomi Y, Ueno K, Kawai Y, Nishida N, Kojima K, Kawashima M, Aiba Y, Nagasaki M, Tokunaga K, Nakamura M
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 日本人の5塩基短鎖重複反復配列のプロファイルと高解像度の反復配列タイピングの検証2018
- Author(s)
  齋藤真梨恵、平田智士、小島要、三沢計治、三森隆広、Gervais O、河合洋介、人見祐基、徳永勝士、中村稔、長﨑正朗
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Identification of POGLUT1 as the effector gene in human primary biliary cholangitis(PBC),susceptibility locus chromosome 3q13.33.2018
- Author(s)
  Yuki Hitomi
- Organizer
  日本免疫学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域NFKB1/MANBAにおける機能的遺伝子多型（causal variant）の同定2018
- Author(s)
  人見祐基、中村稔
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 日本人原発性胆汁性胆管炎の疾患感受性遺伝子POU2AF1、PRKCBの役割の検討2018
- Author(s)
  相葉佳洋、原田憲一、伊東正博、人見祐基、植野和子、小森敦正、八橋弘、長崎正朗、徳永勝士、中村稔
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Identification of POGLUT1 as the effector gene in human primary biliary cholangitis (PBC) susceptibility locus chromosome 3q13.332018
- Author(s)
  人見祐基、相葉佳洋、中村稔
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Pathway-analysis using datasets of GWAS and mRNA expression array identified IFNG as the most significant upstream-regulator in primary biliary cholangitis in the Japanese population.2018
- Author(s)
  Ueno K, Aiba Y, Gervais O, Kawai Y, Hitomi Y, Kojima K, Kawashima M, Nishida N, Shimoda S, Nagasaki M, Tokunaga K, Nakamura M
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 日本人原発性胆汁性胆管炎(PBC)感受性遺伝子領域NFKB1/MANBAにおける機能的遺伝子多型(causal variant)の同定.2018
- Author(s)
  人見祐基
- Organizer
  第54回日本肝臓学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Genome-wide meta-analysis and functional analysis identified POGLUT1 as the effector gene driven by rs2293370 in primary biliary cholangitis (PBC) susceptibility locus chromosome 3q13.33 in the Japanese population.2018
- Author(s)
  Yuki Hitomi
- Organizer
  American Society of Human Genetics.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] 集団ゲノム配列解析による構造多型の探索2018
- Author(s)
  河合洋介、三森隆広、植野和子、人見祐基、Garvais O、Seik SS、川嶋実苗、西田奈央、中村稔、長﨑正朗、徳永勝士
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.2017
- Author(s)
  Kawashima M, Nishida N, Hitomi Y, Kojima K, Kawai Y, Aiba Y, Nakamura H, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  ASHG 2017（The 67th Annual Meeting of the American Society of Human Genetics）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese population.2017
- Author(s)
  Kawashima M, Nishida N, Hitomi Y, Kojima K, Kawai Y, Aiba Y, Nakamura H, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population.2017
- Author(s)
  安波道朗、中村仁美、徳永勝士、川嶋実苗、西田奈央、人見祐基、中村稔
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] GWAS polygenic model approach applied to primary biliary cholangitis (PBC) in a Japanese population.2017
- Author(s)
  Gervais O, Ueno K, Kojima K, Aiba Y, Kawashima M, Kawai Y, Hitomi Y, Tokunaga K, Nakamura M, Nagasaki M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary cholangitis in a Japanese population.2017
- Author(s)
  Yasunami M, Nakamura H, Tokunaga K, Kawashima M, Nishida N, Hitomi Y, Nakamura M.
- Organizer
  The 46th Annual Meeting of The Japanese Society for Immunology.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] GWAS polygenic model approach applied to primary biliary cholangitis (PBC) in a Japanese population.2017
- Author(s)
  Gervais O, Ueno K, Kojima K, Aiba Y, Kawashima M, Kawai Y, Hitomi Y, Tokunaga K, Nakamura M, Nagasaki M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域Chr.17q12-21における機能的遺伝子多型（causal variant）の同定2017
- Author(s)
  人見祐基、西田奈央、相葉佳洋、安波道郎、中村稔
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 原発性胆汁性胆管炎の重症化にカテプシンの果たす役割の検討.2017
- Author(s)
  相葉佳洋, 原田憲一, 相島慎一, 伊東正博, 人見祐基, 西田奈央, 小森敦正, 八橋弘, 中村稔.
- Organizer
  第53回日本肝臓学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Increased expression and altered localization of cathepsin Z is associated with progression to jaundice-stage in primary biliary cholangitis.2017
- Author(s)
  Aiba Y, Harada K, Ito M, Aishima S, Hitomi Y, Nishida N, Kawashima M, Uemoto S, Kokudo N, Takatsuki M, Eguchi S, Shimoda S, Nakamura H, Komori A, Abiru S, Nagaoka S, Yatsuhashi H, Tokunaga K, Nakamura M.
- Organizer
  AASLD The Liver Meeting 2017.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
- Organizer
  ASHG 2017（The 67th Annual Meeting of the American Society of Human Genetics）.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  人見祐基、仲谷健、小島要、西田奈央、河合洋介、川嶋実苗、相葉佳洋、長崎正朗、中村稔、徳永勝士
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] 日本人原発性胆汁性胆管炎（PBC）感受性遺伝子領域Chr.17q12-21における機能的遺伝子多型（causal variant）の同定2017
- Author(s)
  人見祐基、西田奈央、相葉佳洋、安波道郎、中村稔
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  Hitomi Y, Aiba Y, Nakamura M, Tokunaga K.
- Organizer
  The 46th Annual Meeting of The Japanese Society for Immunology.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017
- Author(s)
  Nakamura M, Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
- Organizer
  The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Genome-wide Association Studies Identify PRKCB as A Novel Genetic Susceptibility Locus for Primary Biliary Cholangitis in the Japanese Population.2017
- Author(s)
  Nakamura M,　Kawashima M, Hitomi Y, Aiba Y, Nishida N, Kojima K, Kawai Y, Komori A, Shimoda S, Tanaka A, Nagasaki M, Tokunaga K, PBC consortium in Japan.
- Organizer
  The 26th Conference of the Asian Pacific Association for the Study of the Liver (APASL 2017)
- Place of Presentation
  Shanghai(China)
- Year and Date
  2017-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 日本人原発性胆汁性胆管炎における黄疸型進行関連遺伝子の同定と発現・機能解析.2017
- Author(s)
  相葉佳洋, 西田奈央, 人見祐基, 川嶋実苗, 徳永勝士, 中村稔
- Organizer
  第45回日本臨床免疫学会総会.
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  人見祐基、仲谷健、小島要、西田奈央、河合洋介、川嶋実苗、相葉佳洋、長崎正朗、中村稔、徳永勝士
- Organizer
  日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility gene loci2017
- Author(s)
  人見祐基、相葉佳洋、中村稔、徳永勝士
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Identification of the primary functional variants in primary biliary cholangitis susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  Hitomi Y, Nakatani K, Kojima K, Nishida N, Kawai Y, Kawashima M, Aiba Y, Nagasaki M, Nakamura M, Tokunaga K.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] GWAS polygenic model approach applied to primary biliary cholangitis (PBC) in a Japanese population.2017
- Author(s)
  O. Gervais, Ueno K, Kojima K, Aiba Y, Kawashima M, Kawai Y, Hitomi Y, Tokunaga K, Nakamura M, Nagasaki M.
- Organizer
  ASHG 2017（The 67th Annual Meeting of the American Society of Human Genetics）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04169
[Presentation] NELFCD and CTSZ loci are associated with jaundice-stage progression in primary biliary cholangitis in the Japanese2017
- Author(s)
  Kawashima M, Nishida N, Hitomi Y, Kojima K, Kawai Y, Aiba Y, Nakamura H, Nagasaki M, Tokunaga K, Nakamura M.
- Organizer
  American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Identification of the disease causal variants in human primary biliary cholangitis (PBC) susceptibility gene loci NFKB1/MANBA.2017
- Author(s)
  人見祐基、相葉佳洋、中村稔、徳永勝士
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Principal contribution of HLA-DQ alleles, DQB1*06:04 and DQB1*03:01, to disease resistance against primary biliary2017
- Author(s)
  安波道朗、中村仁美、徳永勝士、川嶋実苗、西田奈央、人見祐基、中村稔
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K15924
[Presentation] Imputation analysis using reference panel of 1,070 Japanese individuals (1KJPN) and in silico / in vitro functional analyses identified functional variants for primary biliary cirrhosis (PBC) susceptibility.2016
- Author(s)
  Hitomi Y, Kojima K, Kawashima M, Kawai Y, Nishida N, Aiba Y, Yasunami M, Nagasaki M, Nakamura M, Tokunaga K.
- Organizer
  International Congress of Human Genetics
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Identification of the primary functional variants for primary biliary cirrhosis (PBC) susceptibility loci by high-density association mapping and in silico/ in vitro functional analyses.2016
- Author(s)
  Hitomi Y, Kojima K, Kawashima M, Kawai Y, Nishida N, Aiba Y, Yasunami M, Nagasaki M, Nakamura M, Tokunaga K.
- Organizer
  American Society of Human Genetics
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2016-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Identification of the causal variants in human primary biliary cirrhosis (PBC) by the combination of a genome-wide association study, whole-genome sequencing, and in silico/ in vitro functional analyses.2016
- Author(s)
  人見祐基、相葉佳洋、中村稔、徳永勝士
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県那覇市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Genome-wide association study identifies PRKCB as a novel genetic factor for primary biliary cirrhosis in the Japanese population.2016
- Author(s)
  Kawashima M, Hitomi Y, Nishida N, Kojima K, Kawai Y, Nakamura H, Yasunami M, Chayama K, Aiba Y, Nagasaki M, Tokunaga K, Nakamura M, PBC Consortium in Japan (PBCCSJ).
- Organizer
  American Society of Human Genetics
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2016-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Genome-wide association study identifies PRKCB as a novel genetic factor for primary biliary cirrhosis in the Japanese population.2016
- Author(s)
  M. Kawashima, Y. Hitomi, N. Nishida, K. Kojima, Y. Kawai, H. Nakamura, M. Yasunami, K. Chayama, Y. Aiba, M. Nagasaki, K. Tokunaga, M. Nakamura, PBC Consortium in Japan (PBCCSJ)
- Organizer
  The 66th American Society of Human Genetics Annual Meeting
- Place of Presentation
  Vancouver(Canada)
- Year and Date
  2016-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 日本人原発性胆汁性肝硬変(PBC)の発症と関連する機能的遺伝子多型(casual variant)の同定2016
- Author(s)
  人見祐基,中村　稔
- Organizer
  第52回　日本肝臓学会総会
- Place of Presentation
  ホテルニューオオタニ幕張　東京ベイ幕張ホール（千葉県千葉市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] Imputation analysis using reference panel of 1,070 Japanese individuals (1KJPN) and in silico / in vitro functional analyses identified functional variants for primary biliary cirrhosis (PBC) susceptibility.2016
- Author(s)
  Yuki Hitomi, Kaname Kojima, Minae Kawashima, Yosuke Kawai, Nao Nishida, Yoshihiro Aiba, Michio Yasunami, Masao Nagasaki, Minoru Nakamura, Katsushi Tokunaga.
- Organizer
  第13回　国際人類遺伝学会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] Fine-mapping analysis of TNFSF15 across leprosy, Crohn’s disease and primary biliary cirrhosis.2016
- Author(s)
  Irwanto A, Sun Y, Hitomi Y, Toyo-oka L, Choi H, Zhang F, Song K, Tokunaga K, Liu JJ, Andiappan AK, Rotzschke O.
- Organizer
  International Congress of Human Genetics
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Identification of the primary functional variants for primary biliary cirrhosis (PBC) susceptibility loci by high-density association mapping and in silico/in vitro functional analyses.2016
- Author(s)
  Y. Hitomi, K. Kojima, M. Kawashima, Y. Kawai, N. Nishida, Y. Aiba, M. Yasunami, M. Nagasaki, M. Nakamura, K. Tokunaga
- Organizer
  The 66th American Society of Human Genetics Annual Meeting
- Place of Presentation
  Vancouver(Canada)
- Year and Date
  2016-10-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 日本人原発性胆汁性肝硬変（PBC）の発症と関連する機能的遺伝子多型（causal variant）の同定2016
- Author(s)
  人見祐基、中村稔
- Organizer
  日本肝臓学会
- Place of Presentation
  東京ベイ幕張ホール（千葉県千葉市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Fine-mapping analysis of TNFSF15 across leprosy, Crohn’s disease and primary biliary cirrhosis2016
- Author(s)
  Irwanto A, Sun Y, Hitomi Y, Toyo-oka L, Choi H, Zhang F, Song K, Tokunaga K, Liu JJ, Andiappan AK, Rotzschke O.
- Organizer
  International Congress of Human Genetics
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] Identification of the casual variants in human primary biliary cirrhosis　(PBC) by the combination of a genome-wide association study, Whole-genome sequencing, and in silico/ in vitro functional analyses.2016
- Author(s)
  HITOMI Yuki, AIBA Yoshihiro, YASUNAMI Michio, NAKAMURA Minoru, TOKUNAGA Katsushi.
- Organizer
  第45回　日本免疫学会総会
- Place of Presentation
  沖縄コンベンションセンター　ラグナガーデンホテル（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 日本人原発性胆汁性肝硬変の疾患感受性遺伝子による病態の解明　シンポジウム1; PBC(原発性胆汁性肝硬変)-臨床、病理と免疫学との接点を求めて2015
- Author(s)
  中村稔, 川嶋実苗, 相葉佳洋, 西田奈央, 人見祐基, 小森敦正, 下田慎治, 田中　篤, 茶山一彰, 太平弘正, 山本和秀, 銭谷幹男, 小島　要, 長崎正朗, 徳永勝士
- Organizer
  第52回日本消化器免疫学会総会
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] ゲノムワイド関連解析から同定された日本人原発性胆汁性肝硬変症発症に抑制的なHLAハプロタイプの効果2015
- Author(s)
  安波道郎, 中村仁美, 徳永勝士, 川嶋実苗, 西田奈央, 人見祐基, 中村稔
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  東京　京王プラザホテル
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] Dissection of HLA class II in Japanese primary biliary cirrhosis: epistasis of protective HLA-DQ allele and additional contribution of HLA-DP allele.2015
- Author(s)
  Yasunami M, Nakamura H, Tokunaga K, Kawashima M, Nishida N, Hitomi Y, Nakamura M.
- Organizer
  American Society for Human Genetics
- Place of Presentation
  Boltimore（USA）
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] 原発性胆汁性肝硬変（PBC）感受性遺伝子TNFSF15に存在するrs4979462は、NF-1結合を介したTNFSF15発現量の亢進に寄与する2015
- Author(s)
  人見祐基、相葉佳洋、中村稔
- Organizer
  日本肝臓学会
- Place of Presentation
  熊本ホテルキャッスル（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] ゲノムワイド関連解析から同定された日本人原発性胆汁性肝硬変発症に抑制的なHLAハプロタイプの効果2015
- Author(s)
  安波道郎、中村仁美、徳永勝士、川嶋実苗、西田奈央、人見祐基、中村稔
- Organizer
  日本人類遺伝学会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] 日本人原発性胆汁性肝硬変の新規疾患感受性遺伝子PRKCB, ETS1の同定2015
- Author(s)
  相葉佳洋, 川嶋美苗, 西田奈央, 人見祐基, 小森敦正, 茶山一彰, 安波道郎, 徳永勝士, 中村　稔
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本　ホテルキャッスル
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] 日本人原発性胆汁性肝硬変の新規疾患感受性遺伝子PRKCB, ETS1の同定2015
- Author(s)
  相葉佳洋、川嶋実苗、西田奈央、人見祐基、小森敦正、茶山一彰、安波道郎、徳永勝士、中村稔
- Organizer
  日本肝臓学会
- Place of Presentation
  熊本ホテルキャッスル（熊本県熊本市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K19314
[Presentation] 原発性胆汁性肝硬変（PBC）感受性遺伝子 TNFSF15 に存在する rs4979462 は, NF1結合を介したTNFSF15 発現量の亢進に寄与する2015
- Author(s)
  人見祐基, 相葉佳洋, 西田奈央, 中村稔
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本　ホテルキャッスル
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293181
[Presentation] Identification of primary cirrhosis-susceptible variant in human TNFSF15 locus and its functional analysis.
- Author(s)
  Hitomi Yuki
- Organizer
  第43回日本免疫学会学術集会.
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26293181

1. Nakamura Minoru (40217906)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
2. 川嶋実苗 (00396706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. 下田慎治 (30279319)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 西田奈央 (50456109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. 安波道郎 (80244127)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. MIYADERA Hiroko (40361464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IIJIMA KAZUMOTO (00240854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 小島要 (10646988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 堀之内智子 (30754593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 長野智那 (60814316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 野津寛大 (70362796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 植野和子 (00794512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 相葉佳洋 (70450955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
14. 長崎正朗 (90396862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKANISHI Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SHIMA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 伊東正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
18. 築地信

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 高槻光寿

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. ジェルベオリビエ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 川合覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HITOMI YUKI 人見 祐基

HITOMI Yuki 人見 祐基

Research Projects

Research Products

Co-Researchers

原発性胆汁性胆管炎の新たな病態解明と治療標的の同定を目指した臨床ゲノム解析

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新たなpost-GWAS方法論による原発性胆汁性胆管炎の発症機序の全貌解明Principal Investigator

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Molecular genetic analysis to elucidate the pathogenesis of primary biliary cholangitis and develop personalized medicine.Principal Investigator

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Joint International Research for identification of disease-susceptible genes and drug-sensitive genes in childhood nephrotic syndrome

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Clarification of the molecular mechanisms of pathogenesis caused by PBC susceptibility genes and their application to personalized medicinePrincipal Investigator

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GWAS-based integrated analysis of PBC to dissect the mechanism of development and progression of primary biliary cholangitis

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Clarification of the molecular mechanisms of pathogenesis caused by PBC susceptibility polymorphismsPrincipal Investigator

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Analysis of disease-pathways and molecular targets by disease-susceptibility genes in primary biliary cholangitis

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Diversity in HLA heterodimers

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[Journal Article] A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis2024

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[Journal Article] A genome-wide association study identified PTPN2 as a population-specific susceptibility gene locus for primary biliary cholangitis.2024

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[Journal Article] The Genetics of Primary Biliary Cholangitis: A GWAS and Post-GWAS Update.2023

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[Journal Article] rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases2023

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[Journal Article] Novel HLA allele associations with susceptibility, staging, symptomatic state, autoimmune hepatitis and hepatocellular carcinoma events for primary biliary cholangitis in the Japanese population2023

Author(s)

HITOMI YUKI 人見祐基

HITOMI Yuki 人見祐基